A heavy ion Bragg peak online detection method and detection system

Abstract

The present invention discloses an online detection method for a heavy ion Bragg peak and a detection system thereof, wherein the detection system includes a treatment machine head to be detected, an acoustic detector, a heavy ion dose detection device, a thin-walled water tank, a three-dimensional moving device and a signal processing device. The detection treatment machine head is arranged on the front side of the thin-walled water tank, and water is arranged in the thin-walled water tank. By detecting the low-intensity heavy ion beam drawn out from the synchrotron accelerator of the treatment machine head, the characteristic law of the acoustic pulse signal of a specific energy beam at different positions behind the Bragg peak is found. At the same time, based on the amplitude data of the acoustic pulse signal detected at the same position, a function law is obtained. In clinical applications, the function law found by this detection method can be used to quickly locate the specific position of the Bragg peak, thereby ensuring that the Bragg peak position is consistent with the planned position.

Description

Technical Field

[0001] The present invention relates to the field of carbon ion acoustic positioning, in particular to a heavy ion Bragg peak online positioning method and a detection system thereof. Background Art

[0002] Heavy ion radiotherapy concentrates the Bragg peak in the tumor region, using its high linear energy density to kill tumor tissue, while simultaneously utilizing the low linear energy density in the plateau region and at the end to minimize the dose to normal tissue. However, due to the objective uncertainty of ion range, when the Bragg peak position deviates from the planned value, the actual dose received by tumor and normal tissue may change accordingly. Therefore, locating the actual position of the Bragg peak in the body is of great significance for heavy ion precision radiotherapy.

[0003] Currently, online Bragg peak localization is not possible in clinical practice. Most existing methods rely on indirect Bragg peak localization via secondary particle decay, which is inefficient and time-consuming. Since the linear energy density increases significantly when heavy ions reach the Bragg peak, this causes the temperature of the medium surrounding the peak to rise rapidly in a short period of time, thereby generating a thermoacoustic effect. Studies have shown that even for low-intensity clinical heavy ion beams (protons and carbon ions) emitted by synchrotrons, their intensity is still correlated with the amplitude of their Bragg peak acoustic pulse signals. Therefore, based on the above theory, the actual location of the heavy ion Bragg peak in clinical practice and the regularity of its dose distribution have become issues that technicians in this field need to explore and solve. Summary of the Invention

[0004] The purpose of the present invention is to overcome the above-mentioned deficiencies in the prior art, realize online detection of low-intensity clinical heavy ion Bragg peaks induced by synchrotron accelerators, and provide a heavy ion Bragg peak online detection method and detection system.

[0005] The technical solution adopted by the present invention to solve the above problems is: a heavy ion Bragg peak online detection method,

[0006] (1) Pre-install the acoustic detector in the liquid medium;

[0007] (2) A low-intensity heavy ion beam from the synchrotron of the treatment head is drawn from the front side of the liquid medium and enters the liquid medium;

[0008] (3) Calculate the theoretical position of the Bragg peak of the synchrotron beam, and adjust the acoustic pulse detector according to the position so that it is located a certain distance behind the Bragg peak. The Bragg peak generates an acoustic pulse signal, which is detected by the acoustic pulse signal detector;

[0009] (4) Move the acoustic detector to detect the acoustic pulse signals at different positions behind the Bragg Peak;

[0010] (5) Using an acoustic wave recording device, characteristic data of the acoustic pulse signals detected by the acoustic detector at different positions behind the Bragg peak in step (3) are collected.

[0011] (6) The acoustic signal function variation law of the same energy beam at different positions after the Bragg peak is obtained from the collected acoustic pulse signal characteristic data.

[0012] As a preference, the liquid medium in step (2) is water and is placed in a transparent water tank.

[0013] As a preferred embodiment, after collecting the acoustic pulse signal in step (4), a heavy ion dose detection device is used to detect the Bragg peak release dose.

[0014] As an example, the characteristic data of the acoustic pulse signal is the amplitude collected by the acoustic wave recording device at the beginning and end of the beam flow.

[0015] As a preferred embodiment, the data collected by the sound wave recording device is uploaded to a network server after being processed to realize online network data synchronous storage.

[0016] The detection system for the above-mentioned heavy ion Bragg peak online detection method includes a treatment head to be detected, an acoustic detector, a heavy ion dose detection device, a thin-walled water tank, a three-dimensional moving device and a signal processing device. The detection treatment head is arranged on the front side of the thin-walled water tank, water is arranged in the thin-walled water tank, the acoustic detector and the heavy ion dose detection device are arranged in the water of the thin-walled water tank, the three-dimensional moving device is arranged on the upper side of the thin-walled water tank and the moving part is connected to the acoustic detector, and the acoustic detector and the heavy ion dose detection device are communicatively connected to the data processing host.

[0017] As a preferred embodiment: the three-dimensional moving device includes an X-axis frame, a Y-axis frame, a Z-axis frame and a fixed seat, the X-axis frame includes two sets of fixed rods and an X-axis rod, the two sets of fixed rods are fixed to the edge of the opening of the thin-walled water tank by fixed claw arms, and adjustment rods are inserted into the two ends of the X-axis rod and fastened by bolts. The adjustment rods at both ends are respectively slidably set in the corresponding sliding grooves of the fixed rods, and a first screw rod is provided in the sliding groove to cooperate with the adjustment rod thread. The first screw rod is connected to the first drive motor to drive the X-axis rod to move along the X-axis direction, and the Y-axis frame slides It is sleeved on the X-axis rod, and a second screw rod is provided on the X-axis rod. The second screw rod is threaded through the Y-axis frame. The second screw rod is connected to the second drive motor to drive the Y-axis frame to move along the Y-axis direction. The Z-axis frame is slidably arranged in the slide groove of the Y-axis frame along the Z-axis direction. The Y-axis frame is provided with an electric telescopic rod, and the telescopic rod end of the electric telescopic rod is fixed to the Z-axis frame. A mounting frame is provided at the bottom of the Z-axis frame. The fixed rod, X-axis frame and Z-axis frame are all provided with scale lines for calibrated positions.

[0018] Preferably: the mounting frame includes a U-shaped frame and a limiting rod, and connecting rods are provided at both ends of the limiting rod, which are slidably set on the sliding groove of the U-shaped frame and fastened by bolts. The U-shaped frame and the limiting rod are respectively rotatably provided with a first positioning seat and a second positioning seat, and the first positioning seat and the second positioning seat are respectively provided with mounting grooves for inserting acoustic detectors and heavy ion dose detection equipment. A rotating shaft is rotatably provided in the Z-axis frame and is fixed to the first positioning seat, and a slot hole is provided on the top of the rotating shaft for adapting to the rotation of a screwdriver.

[0019] As a preferred embodiment, the fixed claw arms are composed of several groups of U-shaped groove blocks.

[0020] Preferably, the acoustic detector adopts a broad-spectrum low-frequency acoustic detector, and the heavy ion dose detection device adopts a finger-shaped ionization chamber detector or a parallel plate detector.

[0021] Compared with the prior art, the present invention has the following advantages and effects:

[0022] (1) This method effectively detects the relationship between the Bragg peak position and the amplitude of the acoustic pulse signal it generates, the relationship between the heavy ion beam intensity and the acoustic pulse signal it generates, and the half-width of the heavy ion Bragg peak. By detecting multiple sets of data to obtain a functional relationship, it can achieve rapid and accurate positioning of the equivalent water depth of the Bragg peak in the patient's clinical heavy ion treatment plan, thereby efficiently ensuring that the actual clinical Bragg peak position is consistent with the planned value, and accurately controlling the dose to the tumor area.

[0023] (2) This method uses only the acoustic signal amplitudes generated at the beginning and end of the beam to represent the acoustic signal amplitude, thereby overcoming the low intensity of the heavy ion beam and the longer time required to produce the same dose, thereby overcoming the characteristic of its insignificant pulse signal, making the data accurate and consistent.

[0024] (3) In this method, a three-dimensional moving device is used to establish a three-dimensional coordinate reference for the detection device. The three-dimensional moving device uses a screw mechanism to enable the detection device fixed thereon to move precisely, thereby meeting its sub-millimeter precision displacement requirements. At the same time, in this three-dimensional moving device, a pulse signal detection device and a dose detection device are respectively installed on the front and rear end faces of the fixed seat, and flipping is achieved by a rotating axis. The structure is easy to adjust, so that while detecting the relationship between the Bragg peak signal position and the acoustic pulse signal, the relationship between the Bragg peak position and the dose distribution can be obtained at the same time. BRIEF DESCRIPTION OF THE DRAWINGS

[0025] Figure 1 It is a schematic structural diagram of a detection system according to an embodiment of the present invention.

[0026] Figure 2 It is a structural diagram of a three-dimensional mobile device according to an embodiment of the present invention.

[0027] Figure 3 It is a structural schematic diagram of a mounting frame according to an embodiment of the present invention.

[0028] Figure 4 This is a graph showing the relationship between the Bragg peak acoustic signal intensity and the distance from the detector to the Bragg peak in Example 2 of the present invention.

[0029] Figure 5 3 is a graph showing the relationship between the Bragg peak acoustic signal intensity and the beam current intensity according to Example 3 of the present invention.

[0030] Figure 6 This is a diagram showing the relationship between the half-width at half maximum of the heavy ion Bragg peak detected by the detection system in Example 4 of the present invention.

[0031] Figure numbers: treatment head 1, acoustic detector 2, thin-walled water tank 3, three-dimensional moving device 4, signal processing equipment 5, Bragg peak 6, fixed rod 41, X-axis rod 42, fixed claw arm 43, adjusting rod 44, first screw rod 45, first drive motor 46, Y-axis axis frame 47, second screw rod 48, second drive motor 49, Z-axis axis frame 410, scale line 411, fixed seat 412, U-shaped frame 413, limit rod 414, connecting rod 415, first positioning seat 416, second positioning seat 417, rotating shaft 418, mounting groove 419, slot hole 420. DETAILED DESCRIPTION

[0032] The present invention will be further described in detail below with reference to the accompanying drawings and through examples. The following examples are intended to explain the present invention but the present invention is not limited to the following examples.

[0033] Example 1:

[0034] A method for online detection of heavy ion Bragg peak 6,

[0035] (1) The acoustic detector 2 is moved in advance and placed in the liquid medium;

[0036] (2) A low-intensity heavy ion beam is drawn from the front side of the liquid medium from the synchrotron of the treatment head 1 and enters the liquid medium;

[0037] (3) Calculating the theoretical position of the Bragg peak 6 of the synchrotron beam, adjusting the acoustic detector 2 according to the theoretical position so that it is located a certain distance behind the Bragg peak 6, and the Bragg peak 6 generates an acoustic pulse signal, which is detected by the acoustic pulse signal detector 2;

[0038] (4) moving the acoustic detector 2 to detect acoustic pulse signals at different positions behind the Bragg peak 6;

[0039] (5) Using an acoustic wave recording device, characteristic data of the acoustic pulse signal detected by the acoustic detector 2 at different positions of the Bragg peak 6 in step (3) are collected.

[0040] (6) The function variation law of the same energy beam at different positions after the Bragg peak 6 is obtained from the collected acoustic pulse signal characteristic data.

[0041] The liquid medium in step (2) is water and is placed in a transparent water tank.

[0042] After collecting the acoustic pulse signal in step (4), a heavy ion dose detection device is used to detect the dose released by the Bragg peak 6.

[0043] The characteristic data of the acoustic pulse signal is the amplitude collected by the acoustic wave recording device at the beginning and end of the beam flow.

[0044] The data collected by the acoustic wave recording device is processed and uploaded to the network server to realize online network data synchronous storage.

[0045] The present invention adopts the above method, adopts water as the liquid medium, and the liquid medium is arranged in a thin-walled water tank 3. The difference between heavy ions of different energies is that the ranges of the heavy ions of different energies in water are different, that is, the distances they can propagate in water are different, high-energy ones have long ranges, and low-energy ones have short ranges. The equivalent water ranges corresponding to different energies of the accelerator are specific, so the theoretical position of the Bragg peak 6 generated by the beam drawn out by the accelerator can be determined. The present invention utilizes detection of the low-intensity heavy ion beam drawn out from the synchrotron accelerator of the treatment machine head 1 to find the characteristic laws of the acoustic pulse signals of the specific energy beam at different positions behind the Bragg peak 6. At the same time, based on the amplitude data of the acoustic pulse signals detected at the same position, a function law is obtained;

[0046] In clinical applications, the position of Bragg peak 6 cannot be directly detected by existing equipment. Therefore, it is necessary to use an acoustic pulse signal detection device to detect it behind the synchrotron. By comparing the acoustic pulse signal amplitude data at the start and end states of the beam detected by the acoustic pulse signal detector with the function law obtained by the above method, the specific position of Bragg peak 6 obtained by the synchrotron beam generated in actual clinical applications can be realized, thereby efficiently ensuring that the actual clinical Bragg peak position is consistent with the planned value, and the dose to the tumor area can be accurately controlled.

[0047] In this embodiment, in order to overcome the low frequency characteristic of the acoustic pulse signal generated by the Bragg peak 6 of the clinical heavy ions (protons and carbon ions) induced by the synchrotron, we use a wide-spectrum low-frequency acoustic detector 2 that can detect sound frequencies between 10 Hz and 2 kHz. In order to overcome the weak clinical heavy ion flow induced by the synchrotron and the resulting weak acoustic pulse signal, the sound waves generated by the heavy ion Bragg peak 6 will continue to propagate and diverge around along the beam direction. The signal intensity is proportional to the flow intensity and inversely proportional to the beam duration. The clinical radiotherapy heavy ion flux generated by the synchrotron is low and lasts for a long time, so its Bragg peak 6 acoustic wave signal is significantly weak. The acoustic pulse signal can only be detected within a certain distance directly behind the Bragg peak 6, and no signal can be detected in other directions. Therefore, we place the acoustic detector 2 behind the heavy ion Bragg peak 6. The clinical proton Bragg peak 6 acoustic pulse signal induced by the synchrotron is significantly weaker than the carbon ion Bragg peak 6 acoustic pulse signal. Therefore, when used for proton Bragg peak 6 acoustic pulse signal detection, the distance between the detector and Bragg peak 6 should be less than 5 mm. In order to collect Bragg peak 6 acoustic pulse signals of sufficient sound intensity, we use the relatively large acoustic pulse signals generated at the beginning and end of the beam as the detection target signal, and obtain the relationship between the acoustic pulse signal amplitude and the flux intensity. This research device can also carry commonly used devices for heavy ion dosimetry research, such as finger-shaped ionization chamber detectors and parallel plate detectors, to accurately detect the dose released by the heavy ion Bragg peak 6.

[0048] The data collected by the acoustic wave recording device described in this embodiment is uploaded to the network server after processing to realize online network data synchronization storage, realize network synchronization of measurement data, facilitate network call query and network storage of data, and also facilitate data aggregation of various laboratories, so that the database is continuously improved.

[0049] Example 2:

[0050] For example, this embodiment is based on the above detection method and aims to study the relationship between the intensity of the heavy ion Bragg acoustic pulse signal and the distance from the detector to the Bragg peak 6. Specifically, this embodiment takes 126.04MeV protons as an example, and defines the distance from the Bragg peak 6 to the detector in the theoretical data as Dpd. First, the acoustic pulse signal detector is placed 4.7 mm behind the proton Bragg peak 6; the beam is emitted and the amplitude of the acoustic pulse start signal and end signal generated by the proton Bragg peak 6 is recorded; after the beam is emitted, the detector is moved 1 mm horizontally to the back, and the above detection and recording are repeated; until the detector can no longer detect the acoustic pulse signal, the detection ends. See the example of the results. Figure 4 As can be seen from the figure, as the distance from Bragg peak 6 continues, the amplitude of the acoustic pulse signal detected at the beginning and end of the beam continues to decrease. According to the detection data, the functional relationship between the distance from Bragg peak 6 and the corresponding acoustic pulse signal amplitude is simulated, that is,

[0051] Function of the acoustic pulse signal at the beginning of the beam and the position of Bragg peak 6: y = 0.7519*Exp(-0.725x);

[0052] The function of the acoustic pulse signal at the end of the beam and the position of Bragg peak 6 is: y = 6.651*Exp(-0.986x);

[0053] In clinical applications, an acoustic pulse signal detection device is used to detect the 124.82 MeV proton beam emitted by the synchrotron accelerator, acting at a water depth equivalent to the patient's affected area, and to detect the amplitude of the acoustic pulse signal behind the synchrotron accelerator. The specific position of Bragg Peak 6 can be inferred from the acoustic pulse signal amplitude value using the above-mentioned functional relationship, thereby ensuring that the position of Bragg Peak 6 is consistent with the planned position.

[0054] The detection method of this embodiment can be used to detect the function of the acoustic pulse signal of different proton beam currents and the position of the Bragg peak 6, so that the specific position relationship of the Bragg peak 6 can be specifically deduced according to the actual selection of the corresponding functional relationship in clinical practice.

[0055] Example 3:

[0056] The purpose of this example is to study the relationship between the intensity of the heavy ion Bragg acoustic pulse signal and the beam current. Taking 125.43 MeV protons as an example, referring to the definition of Dpd in Example 1, the detector is moved to the position just behind the proton Bragg peak 6 using a three-dimensional water tank, and Dpd is fixed at 5.7 mm. Beams with different currents but the same total number of protons are used to emit beams respectively. The amplitudes of the beam start signal and the beam end signal are recorded for each beam emission. Figure 5 It can be seen that as the proton flux increases, the amplitude of the acoustic pulse signal detected at the beginning and end of the beam increases. Based on the detection data, the functional relationship between the proton flux and the corresponding acoustic pulse signal amplitude is simulated, that is,

[0057] The function of the acoustic pulse signal at the beginning of the beam and the proton flux intensity is: y = (2E-11) * x + 0.0078;

[0058] The function of the acoustic pulse signal at the end of the beam and the proton flux intensity is: y = (4E-12) * x + 0.0085;

[0059] In clinical applications, an acoustic pulse signal detection device is used to detect the 125.43 MeV proton beam emitted by the synchrotron accelerator, acting at a water depth equivalent to that of the patient, and to detect the amplitude of the acoustic pulse signal behind the synchrotron accelerator. The corresponding proton beam intensity can be deduced from the acoustic pulse signal amplitude value using the above functional relationship, thereby ensuring that the proton flux intensity acting on the synchrotron accelerator is consistent with the plan.

[0060] The detection method of this embodiment can be used to detect the function of the acoustic pulse signal and the current intensity generated by different proton beam currents, so that the specific current intensity relationship of the Bragg peak 6 can be specifically deduced according to the actual selection of the corresponding functional relationship in clinical practice.

[0061] Example 4:

[0062] This embodiment uses heavy ion Bragg acoustic pulse signals to detect the half-width at half maximum of heavy ion Bragg peak 6. Taking 125.43MeV protons as an example, refer to the Dpd setting in Example 1; fix the Z direction and do not move, only move in the X direction, set the beam center position to zero and start moving toward the Y square at intervals of 1 mm, no beam is emitted during movement, start emitting beams when it moves to the specified position, and record the signal according to the method in Example 1 or 2. After the beam is emitted, move the X axis to the next position, repeat the beam emission and recording; until the detector can no longer detect the signal. Then return to the zero position and repeat the previous measurement in the opposite direction of the X axis. In this way, the full proton Bragg peak 6 in the X-axis direction can be measured and the half-width. See the example of the results. Figure 6 Using the above detection method, the amplitude of the acoustic pulse signal at a fixed distance from the center position of the Bragg peak 6 can be detected. As can be seen from the figure, the amplitude of the acoustic pulse signal gradually decreases and tends to zero as it moves away from the center. Therefore, in this embodiment, the half-height width of the Bragg peak 6 at this position is 17.6 mm (calculated based on the beam start signal). This embodiment can be used to detect the half-height width of the Bragg peak 6 of a specific proton beam, and to detect the lateral dose distribution of the proton beam.

[0063] Example 5:

[0064] The present embodiment specifically relates to a detection system for the above-mentioned online detection method of the heavy ion Bragg peak 6, comprising a treatment machine head 1 to be detected, an acoustic detector 2, a heavy ion dose detection device, a thin-walled water tank 3, a three-dimensional moving device 4, and a signal processing device 5. The detection treatment machine head 1 is arranged on the front side of the thin-walled water tank 3, water is arranged in the thin-walled water tank 3, the acoustic detector 2 and the heavy ion dose detection device are arranged in the water of the thin-walled water tank 3, the three-dimensional moving device 4 is arranged on the upper side of the thin-walled water tank 3 and the moving part is connected to the acoustic detector 2, the acoustic detector 2 and the heavy ion dose detection device are communicatively connected to a data processing host, and the detection of the position regularity and dose distribution regularity of the above-mentioned heavy ion Bragg peak 6 is achieved through this system;

[0065] The specific three-dimensional moving device 4 includes an X-axis frame, a Y-axis frame 47, a Z-axis frame 410 and a fixed seat 412. The X-axis frame includes two groups of fixed rods 41 and an X-axis rod 42. The two groups of fixed rods 41 are fixed to the opening edge of the thin-walled water tank 3 through fixed claw arms 43. Adjustment rods 44 are slidably inserted at both ends of the X-axis rod 42 and fastened by bolts. The adjustment rods 44 at both ends are slidably set in the corresponding slide grooves of the fixed rods 41. A first screw rod 45 is provided in the slide groove to cooperate with the adjustment rod 44 through a thread. The first screw rod 45 is connected to the first drive motor 46 to drive the X-axis rod 42 to move along the X-axis direction. The Y-axis frame 47 is slidably sleeved on the X-axis rod 42. A second screw rod 48 is provided on the X-axis rod 42. The second screw rod 48 is penetrated by a thread. It is arranged on the Y-axis frame 47, and the second screw rod 48 is connected to the second drive motor 49 to drive the Y-axis frame 47 to move along the Y-axis direction. The Z-axis frame 410 is arranged in the slide groove of the Y-axis frame 47 to slide along the Z-axis direction. The Y-axis frame 47 is provided with an electric telescopic rod, and the telescopic rod end of the electric telescopic rod is fixed to the Z-axis frame 410. The bottom of the Z-axis frame 410 is provided with a mounting frame, which is used to install and fix the acoustic detector 2 and the heavy ion dose detection equipment. The fixed rod 41, the X-axis frame and the Z-axis frame 410 are all provided with scale lines 411 for calibrating the position. The position movement of the acoustic detector 2 and the heavy ion dose detection equipment can be realized through this three-dimensional moving device 4, and the detection of the position regularity of the above-mentioned Bragg peak 6 can be realized.

[0066] The mounting frame includes a U-shaped frame 413 and a limiting rod 414, and the two ends of the limiting rod 414 are provided with connecting rods 415 which are slidably set on the sliding groove of the U-shaped frame 413 and fastened by bolts. The U-shaped frame 413 and the limiting rod 414 are respectively rotatably provided with a first positioning seat 416 and a second positioning seat 417, and the first positioning seat 416 and the second positioning seat 417 are respectively provided with mounting grooves 419 adapted to insert the acoustic detector 2 and the heavy ion dose detection equipment. The Z-axis axis frame 410 is rotatably provided with a rotating shaft 418 and fixed with the first positioning seat 416. The top of the rotating shaft 418 is provided with a slot 420 for adapting the rotation of a screwdriver. This structure can be used for Bragg in a fixed position. While the position of peak 6 is regular, the dose data released by the heavy ion Bragg peak 6 at this position is detected, which can provide data support for studying the release dose of Bragg peak 6 at different positions. Specifically, after detecting the acoustic pulse signal at a specific position behind the Bragg peak 6, the rotating shaft is rotated 180° by a screwdriver to change the direction of the acoustic detector 2 and the heavy ion dose detection equipment, while ensuring that the corresponding reference position in the three-dimensional coordinate system remains unchanged, so that the release dose of the Bragg peak 6 at this position can be detected, which is easy to operate. The fixed claw arm 43 is a plurality of groups of U-shaped groove blocks. The acoustic detector 2 described in this embodiment adopts a broad-spectrum low-frequency acoustic detector 2, and the heavy ion dose detection equipment adopts a finger-shaped ionization chamber detector or a parallel plate detector.

[0067] The above contents described in this specification are merely examples of the present invention. Those skilled in the art may make various modifications, additions, or substitutions to the described embodiments, without departing from the contents of this specification or exceeding the scope defined by the claims, and such modifications, additions, or substitutions may be made to the described embodiments. Such modifications, additions, or substitutions may be made by persons skilled in the art. Such modifications, additions, or substitutions may be made to the described embodiments without departing from the contents of this specification or exceeding the scope defined by the claims, and such modifications shall fall within the scope of protection of the present invention.

Claims

1. A method for online detection of heavy ion Bragg peaks, characterized by: (1) Pre-install the acoustic detector in the liquid medium; (2) A low-intensity heavy ion beam from the synchrotron of the treatment head enters the liquid medium from the front side of the liquid medium; (3) Calculate the theoretical position of the Bragg peak of the synchrotron beam, adjust the acoustic pulse detector based on this position so that it is located a certain distance behind the Bragg peak, and detect the acoustic pulse signal generated by the Bragg peak by the acoustic pulse signal detector; (4) Use a mobile acoustic detector to detect acoustic pulse signals at different locations behind the Bragg Peak; (5) using an acoustic wave recording device to collect characteristic data of the acoustic pulse signal detected by the acoustic detector at different positions behind the Bragg peak in step (3); (6) The acoustic signal function variation law of the same energy beam at different positions after the Bragg peak is obtained from the collected acoustic pulse signal characteristic data.

2. The method for online detection of heavy ion Bragg peaks according to claim 1, wherein: The liquid medium in step (2) is water and is placed in a transparent water tank.

3. The method for online detection of heavy ion Bragg peaks according to claim 1, wherein: After collecting the acoustic pulse signal in step (4), a heavy ion dose detection device is used to detect the Bragg peak release dose.

4. The method for online detection of heavy ion Bragg peaks according to claim 1, wherein: The characteristic data of the acoustic pulse signal is the amplitude collected by the acoustic wave recording device at the beginning and end of the beam flow.

5. The method for online detection of heavy ion Bragg peaks according to claim 1, wherein: The data collected by the sound wave recording device is processed and uploaded to the network server to realize online network data synchronous storage.

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