Device for observing radiation characteristics of high-energy ions interacting with matter in a bragg peak region

By designing a device that includes a transparent enclosure, beam shaping, collimation, and online adjustment mechanisms, the interaction between high-energy ions and matter in the Bragg peak region can be monitored in real time. This solves the problem of lack of real-time monitoring during heavy ion beam therapy and promotes the application of ion beam technology in the biomedical field.

CN121208048BActive Publication Date: 2026-04-24NORTHWEST NORMAL UNIVERSITY
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
NORTHWEST NORMAL UNIVERSITY
Filing Date
2025-11-27
Publication Date
2026-04-24

AI Technical Summary

Technical Problem

Current technologies lack methods for real-time monitoring of the interaction between high-energy ions and matter in the Bragg peak region during heavy ion beam therapy, which limits in-depth research on the interaction mechanism between ion beams and biological tissues and the optimization and widespread application of heavy ion beam therapy technology.

Method used

Design a device comprising a transparent enclosure, a beam shaping mechanism, a beam collimation mechanism, an online adjustment mechanism, and an X-ray detector, to measure the X-ray spectrum of the interaction between high-energy ions and the analyte in real time by adjusting the penetration path of the high-energy ion beam.

Benefits of technology

It enables real-time and precise monitoring of the interaction between high-energy ions and matter in the Bragg peak region, providing data support for basic physics research and heavy ion therapy, and promoting the application of ion beam technology in the biomedical field.

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Abstract

The application relates to the technical field of high-energy ion irradiation, and provides a device for observing radiation characteristics of high-energy ions and substances in a Bragg peak area, which comprises a transparent box body, a beam shaping mechanism, a beam collimating mechanism, an online adjusting mechanism and an X-ray detector; the beam shaping mechanism and the beam collimating mechanism are oppositely arranged on the outer wall of the transparent box body; the online adjusting mechanism is provided with a sample stage and is used for adjusting the position of the sample stage; and the X-ray detector is used for collecting X-ray spectrum information generated by the interaction between high-energy ions and substances in real time. The device for observing radiation characteristics of high-energy ions and substances in a Bragg peak area can place the measured substances at different positions on the ion beam transmission path, obtain the radiation characteristics of the interaction between the ion beam and the target substances under different energies, and provide help for the accurate positioning of the Bragg peak area and heavy ion treatment.
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Description

Technical Field

[0001] This invention relates to the field of high-energy ion irradiation technology, and in particular to a device for observing the radiation characteristics of high-energy ions interacting with matter in the Bragg peak region. Background Technology

[0002] Ion beam irradiation, as a cutting-edge physics technique, has shown broad application prospects in many fields such as ion beam analysis, materials modification, biomedicine, and environmental remediation. During the interaction between the ion beam and matter, high-energy ions trigger a series of complex physical phenomena, including various radiation effects. The radiation characteristics are particularly crucial in the Bragg peak region, the area where high-energy ion deposition reaches its peak. These radiation characteristics not only reveal the microscopic mechanisms of ion beam-matter interaction but also provide important information on ion beam energy deposition and charge state distribution, which has profound significance for both fundamental physics research and practical applications.

[0003] In the medical field, heavy ion beam therapy, as an advanced cancer treatment method, can precisely kill tumor cells while minimizing damage to surrounding healthy tissues due to its high-precision energy deposition characteristics. However, a mature technology is currently lacking to achieve in-situ online monitoring during heavy ion beam therapy. This technological bottleneck severely limits in-depth research into the interaction mechanism between ion beams and biological tissues, thus affecting the further optimization of heavy ion beam therapy technology and its widespread clinical application. Therefore, inventing a technology that can reflect the microscopic mechanism and comprehensively monitor the interaction process between high-energy ions and matter in the Bragg peak region during ion beam therapy in real time is of paramount importance for promoting the application of ion beam technology in the biomedical field. Summary of the Invention

[0004] This invention provides a device for observing the radiation characteristics of high-energy ions interacting with matter in the Bragg peak region. It enables real-time and accurate measurement of the X-ray spectrum of high-energy ions interacting with the analyte at any location along the penetration path, providing a foundation for basic physics research and heavy ion therapy monitoring.

[0005] This invention provides a device for observing the radiation characteristics of high-energy ion-matter interactions in the Bragg peak region, comprising: a transparent enclosure; a beam shaping mechanism disposed on the outer wall of the transparent enclosure and communicating with the interior of the transparent enclosure, the beam shaping mechanism being used to control the propagation path of the high-energy ion beam; a beam collimation mechanism disposed on the outer wall of the transparent enclosure, the beam collimation mechanism including a collimation support and a fluorescent sheet, the fluorescent sheet being disposed on the collimation support and disposed opposite to the beam shaping mechanism, the fluorescent sheet being used to collimate the high-energy ion beam; an online adjustment mechanism, part of the online adjustment mechanism being located inside the transparent enclosure, the online adjustment mechanism having a stage for placing a sample dish containing a analyte, the online adjustment mechanism being used to adjust the position of the stage; and an X-ray detector disposed on the online adjustment mechanism, the X-ray detector being used to collect X-ray spectral information generated by the interaction between the high-energy ion beam and the analyte.

[0006] According to the present invention, an apparatus for observing the radiation characteristics of high-energy ion-matter interactions in the Bragg peak region further includes a support assembly; the online adjustment mechanism includes: a first adjustment assembly disposed on the top surface of the transparent housing, the first adjustment assembly being partially connected to the support assembly, and the first adjustment assembly being used to move the stage along a first direction; a second adjustment assembly partially connected to the support assembly, the second adjustment assembly being used to move the stage along a second direction; and a third adjustment assembly connected to the second adjustment assembly, the stage being disposed on the third adjustment assembly, and the third adjustment assembly being used to move the stage along a third direction; wherein the first direction, the second direction, and the third direction are arranged perpendicularly to each other.

[0007] According to the present invention, an apparatus for observing the radiation characteristics of high-energy ion-matter interaction in the Bragg peak region is provided. The first adjustment component includes: a pair of slide modules, the pair of slide modules being arranged parallel to each other on the top surface of the transparent box; at least one pair of first sliders, each slide module having at least one first slider, the first sliders being partially connected to the support assembly, and the slide modules being capable of driving the first sliders to move along the first direction.

[0008] According to the present invention, an apparatus for observing the radiation characteristics of high-energy ion-matter interaction in the Bragg peak region is provided. The support assembly includes: a pair of first supports, the pair of first supports being arranged in parallel, and the same side of the pair of first supports being connected to at least one first slider on a slide module; a second support, the two ends of the second support being respectively connected to the pair of first supports; and a third support, the third support being arranged perpendicularly to and connected to the second support, and the third support being connected to the second adjustment component.

[0009] According to the present invention, an apparatus for observing the radiation characteristics of high-energy ion-matter interaction in the Bragg peak region is provided. The second bracket is provided with a first fixing hole, the first fixing hole having an inclined angle. The X-ray detector includes a first X-ray detector, and the first fixing hole is used to fix the first X-ray detector. The third bracket is provided with a second fixing hole, and the X-ray detector further includes a second X-ray detector, the second fixing hole being used to fix the second X-ray detector.

[0010] According to the present invention, an apparatus for observing the radiation characteristics of high-energy ion-matter interaction in the Bragg peak region is provided. The second adjustment component includes: a first base plate, wherein the stage is disposed on the first base plate; and a first driver, wherein the two ends of the first driver are respectively connected to the third support and the first base plate, and the first driver is used to drive the first base plate to move along a second direction.

[0011] According to the present invention, an apparatus for observing the radiation characteristics of high-energy ion-matter interaction in the Bragg peak region is provided. The third adjustment component includes: a second driver; a transmission structure connected to the second driver; a base disposed on a first base plate, the base being rotatably connected to the transmission structure; a second slider connected to the transmission structure; a stage disposed on the second slider; and the second driver being used to drive the second slider to move along the third direction via the transmission structure.

[0012] According to the present invention, a device for observing the radiation characteristics of high-energy ion-matter interaction in the Bragg peak region is provided. The transmission structure includes: a lead screw, which passes through the base and the second slider and is rotatable relative to the base, and the rotation of the lead screw can drive the second slider to move; a rotating wheel connected to the lead screw; and a belt sleeved on the rotating wheel and the output shaft of the second driver to make the two rotate synchronously.

[0013] According to the present invention, an apparatus for observing the radiation characteristics of high-energy ion-matter interactions in the Bragg peak region is provided. The beam shaping mechanism includes: an adapter connected to the transparent housing, the adapter having a first through hole communicating with the interior of the transparent housing; a beam limiting block connected to the adapter, the beam limiting block having a second through hole communicating with the first through hole; and a beam de-energizer connected to the beam limiting block, the interior of the beam de-energizer communicating with the second through hole.

[0014] According to the present invention, an apparatus for observing the radiation characteristics of high-energy ion-matter interaction in the Bragg peak region further includes: a second base plate, wherein the transparent box is disposed on the second base plate; and a plurality of adjusting members disposed along the circumference of the second base plate, wherein the adjusting members are used to level the second base plate.

[0015] The device provided by this invention for observing the radiation characteristics of high-energy ion-matter interactions in the Bragg peak region, by setting up a transparent box, a beam shaping mechanism, a beam collimation mechanism, an online adjustment mechanism, and an X-ray detector, adjusts the penetration path of the high-energy ion beam, so that the high-energy ion beam interacts with the target material at different positions on the penetration path, and obtains the X-ray spectra generated by the interaction between the ion beam and the target material at different energies. This allows for the study of the microscopic evolution process of high-energy ion-matter interactions, and provides assistance for the precise localization of the Bragg peak region and heavy ion therapy. Attached Figure Description

[0016] To more clearly illustrate the technical solutions in this invention or the prior art, the drawings used in the description of the embodiments or the prior art will be briefly introduced below. Obviously, the drawings described below are some embodiments of this invention. For those skilled in the art, other drawings can be obtained from these drawings without creative effort.

[0017] Figure 1 This is a schematic diagram of the device provided by the present invention for observing the radiation characteristics of high-energy ions interacting with matter in the Bragg peak region.

[0018] Figure 2 This is a schematic diagram of the structure of the first adjustment component.

[0019] Figure 3 This is a schematic diagram of the second adjustment component.

[0020] Figure 4 This is a schematic diagram of the third adjustment component.

[0021] Figure 5 This is a schematic diagram of the collimation support structure.

[0022] Figure 6This is a schematic diagram of the second support structure.

[0023] Figure 7 This is a schematic diagram of the third support structure.

[0024] Figure 8 This is a structural diagram of the adapter.

[0025] Figure 9 This is a schematic diagram of the beam de-energizer.

[0026] Figure 10 This is the spectrum of X-rays directly acting on the iodine analyte.

[0027] Figure 11 It is a spectrum of X-rays acting on the iodine analyte after passing through the water.

[0028] Figure label:

[0029] 1. Transparent enclosure; 2. Online adjustment mechanism; 31. First X-ray detector; 32. Visible light spectrometer; 33. Lens tube; 41. Adapter; 42. Beam confinement block; 43. Beam de-energizer; 11. Top plate; 51. Second bottom plate; 52. Adjustment component; 71. First support; 72. Second support; 73. Third support; 74. Fourth support; 81. Collimation support; 9. Stage; 10. Sample dish;

[0030] 201. Slide module; 202. First slider; 211. First driver; 212. First base plate; 221. Second driver; 222. Rotating wheel; 223. Belt; 224. Lead screw; 225. Base; 226. Second slider; 231. Controller; 411. First through hole; 412. First ring; 413. Second ring; 4121. First threaded hole; 4131. Second threaded hole; 721. First fixing hole; 722. Third fixing hole; 731. Second fixing hole. Detailed Implementation

[0031] To make the objectives, technical solutions, and advantages of this invention clearer, the technical solutions of this invention will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only some, not all, of the embodiments of this invention. All other embodiments obtained by those skilled in the art based on the embodiments of this invention without creative effort are within the scope of protection of this invention.

[0032] The following is combined Figures 1-11 The present invention describes an apparatus for observing the radiation characteristics of high-energy ion-matter interactions in the Bragg peak region.

[0033] like Figure 1As shown in the embodiments of the present invention, the device for observing the radiation characteristics of high-energy ion-matter interactions in the Bragg peak region includes: a transparent box 1, a beam shaping mechanism, a beam collimation mechanism, an online adjustment mechanism 2, and an X-ray detector. The transparent box 1 can be an empty box, or it can be filled with liquid or solid. Liquid and solid can not only serve as moderators for studying the Bragg peak region, but also provide test conditions that are closer to actual application scenarios.

[0034] Both the beam shaping mechanism and the beam collimation mechanism are located on the outer wall of the transparent housing 1. The beam shaping mechanism is connected to the interior of the transparent housing 1. The high-energy ion beam enters the transparent housing 1 through the beam shaping mechanism. The beam shaping mechanism is used to control the propagation path of the high-energy ion beam, ensuring the accuracy of the radiation measurement area, avoiding unnecessary interference, and improving the clarity of the measurement area. The beam collimation mechanism includes a collimation bracket 81 and a fluorescent sheet. The collimation bracket 81 is located on the outer wall of the transparent housing 1, and the fluorescent sheet is located on the collimation bracket 81. The fluorescent sheet is opposite to the beam shaping mechanism and is used to collimate the high-energy ion beam. When the high-energy ion beam passes through the transparent housing 1 and hits the fluorescent sheet, it will cause the fluorescent sheet to change color.

[0035] Part of the online adjustment mechanism 2 is housed within the transparent enclosure 1. The online adjustment mechanism 2 includes a stage 9 for holding a sample dish 10, which in turn holds the analyte. The online adjustment mechanism 2 is used to adjust the position of the stage 9 online, ensuring that the center lines of the beam shaping mechanism, the sample dish 10, and the fluorescent sheet are aligned, thus allowing the high-energy ion beam to strike the sample dish 10. The online adjustment mechanism 2 also adjusts the distance between the sample dish 10 and the beam shaping mechanism. An X-ray detector is located within the online adjustment mechanism 2 and is used to collect X-ray spectral information generated by the interaction between the high-energy ion beam and the analyte.

[0036] Specifically, such as Figure 5As shown, the collimator 81 has multiple concentric circles, and a circular or square groove is located at the center of the collimator 81, within which the fluorescent sheet is placed. When a high-energy ion beam strikes the surface of the fluorescent sheet, the fluorescent sheet emits light and its color deepens, indicating that the high-energy ion beam has struck the fluorescent sheet. When the online adjustment mechanism 2 operates, it moves the stage 9, causing the centerline of the sample dish 10, the centerline of the fluorescent sheet, and the centerline of the beam shaping mechanism to be collinear. At this time, the high-energy ion beam passes through the wall of the transparent box 1 and strikes the sample dish 10. When the transparent box 1 contains liquid or solid, the high-energy ion beam, after passing through the liquid or solid, collides with the analyte in the sample dish 10, resulting in radiation behavior. The X-ray detector collects the X-ray spectral information during the radiation process. In this embodiment, when the online adjustment mechanism 2 moves, the distance from the high-energy ion beam to the sample dish 10 can be adjusted. By recording the changes in X-ray spectral information along the transmission path of the high-energy ion beam with the penetration distance, the ionization and excitation information of related atoms in the Bragg peak region can be analyzed through spectral information. At the same time, the accurate position of the Bragg peak region can be accurately measured by utilizing the characteristics of the spectrum and the distribution of ionized states.

[0037] In an embodiment of the present invention, the top plate 11 of the transparent box 1 has a through groove so that a portion of the online adjustment mechanism 2 is located inside the transparent box 1 through the through groove.

[0038] Optionally, in an embodiment of the present invention, the transparent box 1 can be made of acrylic material, with dimensions of 40cm×20cm×20cm, and the diameter or side length of the groove for setting the fluorescent sheet is 2.5cm.

[0039] The device provided in this invention for observing the radiation characteristics of high-energy ion-matter interactions in the Bragg peak region, by setting up a transparent box, a beam shaping mechanism, a beam collimation mechanism, an online adjustment mechanism, and an X-ray detector, adjusts the penetration path of the high-energy ion beam, so that the high-energy ion beam interacts with the target material at different positions along the propagation path, and collects X-ray spectra generated by the interaction between the ion beam and the target material at different energies. This allows for the study of the microscopic evolution process of high-energy ion-matter interactions, providing assistance for the precise localization of the Bragg peak region and heavy ion therapy.

[0040] In an embodiment of the present invention, the device for observing the radiation characteristics of high-energy ion-matter interactions in the Bragg peak region further includes a support assembly. The online adjustment mechanism includes a first adjustment assembly, a second adjustment assembly, and a third adjustment assembly. The first adjustment assembly is disposed on the top surface of the transparent housing 1 and is partially connected to the support assembly. The first adjustment assembly is used to move the stage 9 along a first direction. The second adjustment assembly is partially connected to the support assembly and is used to move the stage 9 along a second direction. The third adjustment assembly is connected to the second adjustment assembly, and the stage 9 is disposed on the third adjustment assembly. The third adjustment assembly is used to move the stage 9 along a third direction, wherein the first direction, the second direction, and the third direction are perpendicular to each other.

[0041] Specifically, in this embodiment, a support assembly is provided to connect the first adjustment assembly, the second adjustment assembly, and the third adjustment assembly into a whole. When the first adjustment assembly moves along the first direction, i.e., the length direction of the transparent box 1, it can drive the stage 9 to move along the first direction. When the second adjustment assembly moves along the second direction, i.e., the height direction of the transparent box, it can drive the stage 9 to move along the second direction. When the third adjustment assembly moves along the third direction, it can drive the stage 9 to move along the third direction, thereby making the center line of the beam shaping mechanism, the center line of the sample dish 10, and the center line of the fluorescent sheet collinear. At the same time, the distance between the sample dish 10 and the beam shaping mechanism can be adjusted to collect X-ray spectra generated by the interaction between ion beams and target materials at different energies.

[0042] like Figure 2 As shown, the first adjustment assembly includes a pair of slide modules 201 and at least a pair of first sliders 202. The pair of slide modules 201 are arranged in parallel on the top plate 11, and each slide module 201 is provided with at least one first slider 202. The first slider 202 is partially connected to the support assembly, and the slide module 201 can drive the first slider 202 to move along the length direction of the transparent box 1.

[0043] Optionally, in this embodiment, the slide module 201 may include a motor and a lead screw. The first slider 202 is sleeved on the lead screw. When the motor rotates, it drives the lead screw to rotate, thereby driving the first slider 202 to move. When the first slider 202 moves, it can drive the support assembly to move, thereby driving the stage 9 to move along the length direction of the transparent box 1 to adjust the penetration distance of the high-energy ion beam.

[0044] like Figure 3As shown, in an embodiment of the present invention, the support assembly includes: a pair of first supports 71, a second support 72, and a third support 73. The pair of first supports 71 are arranged in parallel, and the same side of the pair of first supports 71 is connected to at least one first slider 202 on a slide module 201. Optionally, in this embodiment, each slide module 201 may be provided with one or two first sliders 202. When the number of first sliders 202 is one, the first slider 202 is connected to the same side of the pair of first supports 71; when the number of first sliders 202 is two, each first slider 202 is connected to one end of a first support 71. The two ends of the second support 72 are respectively connected to the pair of first supports 71, and the third support 73 is arranged perpendicularly to and connected to the second support 72. The third support 73 is connected to a second adjustment component.

[0045] Furthermore, such as Figure 6 As shown, the second bracket 72 is provided with at least one first fixing hole 721, and the first fixing hole 721 has an inclined angle. The X-ray detector includes at least one first X-ray detector 31, and the first fixing hole 721 is used to fix the first X-ray detector 31. Optionally, the number of first fixing holes 721 can also be two, and when the number of first fixing holes 721 is two, the two first fixing holes 721 are symmetrically arranged. Optionally, in this embodiment, the inclined angle of the first fixing hole 721 is 45°. Figure 6 As shown, at least one third fixing hole 722 may also be provided on the second bracket 72. The tilt angle of the third fixing hole 722 is 60°. The third fixing hole 722 is also used to fix the first X-ray detector 31, so that the first X-ray detector 31 has different tilt angles. Optionally, when there are two third fixing holes 722, the two third fixing holes 722 are symmetrically arranged.

[0046] like Figure 7 As shown, the third bracket 73 is provided with at least one second fixing hole 731, and the X-ray detector also includes at least one second X-ray detector. The second fixing hole 731 is used to fix the second X-ray detector. Optionally, the number of second fixing holes 731 can also be two. When the number of second fixing holes 731 is two, the two second fixing holes 731 are symmetrically arranged.

[0047] When there are two first X-ray detectors 31 and two second X-ray detectors, the two first X-ray detectors 31 are respectively set in the two first fixing holes 721, and the four X-ray detectors are located around the sample dish 10. The receiving end of each X-ray detector faces the sample dish 10 so as to effectively collect the spectral information of X-rays.

[0048] Furthermore, the position of each X-ray detector within the fixed hole is adjustable to adjust the distance between the receiving end of the X-ray detector and the sample dish 10.

[0049] like Figure 4 As shown, in an embodiment of the present invention, the second adjustment component includes a first driver 211 and a first base plate 212. The two ends of the first driver 211 are respectively connected to the third bracket 73 and the first base plate 212. The first driver 211 is used to drive the first base plate 212 to move along the height direction of the transparent box 1, thereby adjusting the height of the platform 9. Optionally, in this embodiment, the first driver 211 can be a cylinder, a hydraulic cylinder, etc. The first base plate 212 can be made of high-purity aluminum.

[0050] like Figure 4 As shown, in an embodiment of the present invention, the third adjustment component includes: a second driver 221, a transmission structure, a base 225, and a second slider 226. The second driver 221 is connected to the transmission structure. The base 225 is disposed on the first base plate 212 and rotatably connected to the transmission structure. The second slider 226 is connected to the transmission structure, and the stage 9 is disposed on the second slider 226. The second driver 221 can drive the second slider 226 to move along a third direction through the transmission structure, thereby driving the stage 9 to move along a third direction. Simultaneously, the first driver 211 can drive the stage 9 to move along a second direction through the first base plate 212 and the base 225.

[0051] Furthermore, the transmission structure includes a rotating wheel 222, a belt 223, and a lead screw 224. The lead screw 224 passes through the second slider 226 and the base 225 and is rotatable relative to the base 225. A slide rail is provided on the surface of the base 225 opposite to the second slider 226, allowing the second slider 226 to slide along the slide rail. The rotating wheel 222 is connected to the lead screw 224, and the belt 223 is sleeved around the output shaft of the rotating wheel 222 and the second driver 221 to ensure synchronous rotation. When the second driver 221 rotates, it drives the rotating wheel 222 to rotate, which in turn drives the lead screw 224 to rotate, causing the second slider 226 to move along the lead screw 224, thereby moving the stage 9 along the width direction of the transparent housing 1. Optionally, the second driver 221 can be a servo motor.

[0052] like Figure 1 As shown, in an embodiment of the present invention, the online adjustment mechanism 2 further includes a controller 231. The controller 231 is electrically connected to the slide module 201, the first driver 211 and the second driver 221. The controller 231 is used to control the movement of the slide module 201, the first driver 211 and the second driver 221 to drive the stage 9 to move, thereby adjusting the position of the sample dish 10.

[0053] like Figure 1, Figure 8 and Figure 9 As shown, the beam shaping mechanism includes an adapter 41, a beam confinement block 42, and a beam de-energizer 43 connected in sequence. The adapter 41 is connected to the transparent housing 1 and has a first through hole 411. The beam confinement block 42 has a second through hole. The first through hole, the second through hole, and the beam de-energizer 43 are connected, and the center line of the first through hole is collinear with the center line of the sample dish 10. The beam de-energizer 43 is used to control the propagation path of the high-energy ion beam, ensuring the accuracy of the radiation measurement area, avoiding unnecessary interference, and improving the clarity of the measurement area. Optionally, in this embodiment, the beam confinement block 42 can be a hollow cylinder made of copper.

[0054] Optionally, in this embodiment, the adapter 41 includes a first ring 412 and a second ring 413. The first ring 412 has a first through hole 411, and the second ring 413 is disposed at the first through hole 411. The first ring 412 has a plurality of first threaded holes 4121 along its circumference, and bolts are inserted into the first threaded holes 4121 to connect the first ring 412 to the transparent housing 1. The wall surface of the second ring 413 has a plurality of second threaded holes 4131, and bolts pass through the second threaded holes 4131 to connect the second ring 413 to the restraint block 42.

[0055] Optionally, in an embodiment of the present invention, the outer diameter of the first ring 412 is 120 mm, the inner diameter of the second ring 413 is 50 mm, the diameter of the first threaded hole 4121 is 3.6 mm, and the diameter of the second threaded hole 4131 is 2.5 mm.

[0056] like Figure 1 As shown in the embodiment of the present invention, the device for observing the radiation characteristics of high-energy ion-matter interaction in the Bragg peak region further includes: a second base plate 51 and multiple adjusting members 52. A transparent box 1 is disposed on the second base plate 51, and adjusting members 52 are provided at each of the four corners of the second base plate 51. The adjusting members 52 pass through the second base plate 51. By rotating the adjusting members 52, the length of the adjusting members 52 below the second base plate 51 can be adjusted, thereby adjusting the height of each corner of the second base plate 51, so that the transparent box 1 is in a horizontal state. In this embodiment, the adjusting members 52 are bolts.

[0057] like Figure 4As shown in the embodiment of the present invention, the device for observing the radiation characteristics of high-energy ions interacting with matter in the Bragg peak region further includes a microscope tube 33, an optical fiber, a fourth support 74, and a visible light spectrometer 32. The microscope tube 33 is mounted on the fixed end of the first driver 211 via a mounting base. Optical components are housed within the microscope tube 33. The microscope tube 33 is positioned adjacent to the sample dish 10 and is connected to the optical fiber. The fourth support 74 is connected to the third support 73 and is used to fix the visible light spectrometer 32. The optical fiber is connected to the visible light spectrometer 32. The visible light spectrometer 32 is used to collect the visible light spectral information of the high-energy ion beam. When the high-energy ion beam strikes the sample dish 10, visible light can be transmitted through the microscope tube 33 and the optical fiber to the visible light spectrometer 32 to collect the visible light spectral information generated by the interaction between the high-energy ion beam and the analyte. In this embodiment, the maximum displacement of the first base plate 212 moved upward by the first driver 211 is 5 mm, and the fourth support 74 will not interfere with the upward movement of the first base plate 212.

[0058] The following details how to use the apparatus provided in this embodiment of the invention for observing the radiation characteristics of high-energy ion-matter interactions in the Bragg peak region to conduct radiation observation and testing:

[0059] The X-ray radiation signal was obtained by using an XR-100SDD silicon drift tube X-ray detector combined with an Amptek PX5 digital pulse processor. Subsequent data acquisition was performed using a computer running Windows 11 64-bit operating system.

[0060] This invention embodiment is based on the 260MeV / u high-energy C2O3 provided by the heavy ion center point scanning therapy terminal in Wuwei. 6+ Ion beam, beam current intensity approximately 10 8 Experimental tests were conducted using the fluorescent sheet collimation method of this invention. 4g of iodine powder was dissolved in 100mL of anhydrous ethanol, resulting in approximately 9.5 × 10⁻⁶ iodine atoms per milliliter. 19 The prepared iodine solution is added to a cubic glass sample dish 10 with an inner diameter and thickness of about 1 mm and placed on the stage 9. Pure water is added to the transparent box 1 as a decelerator. The stage 9 is moved step by step along the direction of the beam to measure the X-ray spectral information of the target material at different positions. Figure 10 and Figure 11 They respectively demonstrated C with an energy of 260 MeV / u 6+ Experimental observations of X-ray spectra were conducted by directly applying an ion beam to an iodine analyte and by applying the beam to the iodine analyte after passing through a 12 mm body of water. Information such as ionization and excitation of atoms at the Bragg peak can be analyzed from the spectra. Furthermore, the precise location of the Bragg peak can be accurately measured using the spectral structure and ionization state distribution.

[0061] Finally, it should be noted that the above embodiments are only used to illustrate the technical solutions of the present invention, and not to limit them; although the present invention has been described in detail with reference to the foregoing embodiments, those skilled in the art should understand that modifications can still be made to the technical solutions described in the foregoing embodiments, or equivalent substitutions can be made to some of the technical features; and these modifications or substitutions do not cause the essence of the corresponding technical solutions to deviate from the spirit and scope of the technical solutions of the embodiments of the present invention.

Claims

1. A device for observing the radiation characteristics of high-energy ion-matter interactions in the Bragg peak region, characterized in that, include: A transparent box, which can be an empty box or a liquid or solid can be placed inside the transparent box, and the liquid or solid can be used as a decelerator; A beam shaping mechanism is located on the outer wall of the transparent box and communicates with the interior of the transparent box. The beam shaping mechanism is used to control the propagation path of the high-energy ion beam. A beam collimation mechanism is disposed on the outer wall of the transparent box. The beam collimation mechanism includes a collimation support and a fluorescent sheet. The fluorescent sheet is disposed on the collimation support and is disposed opposite to the beam shaping mechanism. The fluorescent sheet is used to collimate the high-energy ion beam. An online adjustment mechanism is partially located within the transparent enclosure. The online adjustment mechanism includes a stage for placing a sample dish containing iodine. The online adjustment mechanism is used to adjust the position of the stage so that the centerline of the beam shaping mechanism, the centerline of the sample dish, and the centerline of the fluorescent sheet are aligned. The online adjustment mechanism also adjusts the distance between the sample dish and the beam shaping mechanism. An X-ray detector is installed in the online adjustment mechanism. The X-ray detector is used to collect X-ray spectral information generated by the interaction of ion beams of different energies with the analyte. The X-ray spectral information can be used to study the microscopic evolution process of the interaction between high-energy ions and matter, and to help with the precise localization of the Bragg peak region and heavy ion therapy.

2. The apparatus for observing the radiation characteristics of high-energy ion-matter interactions in the Bragg peak region according to claim 1, characterized in that, It also includes support components; The online adjustment mechanism includes: A first adjustment component is disposed on the top surface of the transparent box, and the first adjustment component is partially connected to the support assembly. The first adjustment component is used to drive the platform to move along a first direction. The second adjustment component is partially connected to the support assembly, and the second adjustment component is used to drive the platform to move along the second direction; A third adjustment component is connected to the second adjustment component, and the stage is disposed on the third adjustment component. The third adjustment component is used to drive the stage to move in a third direction. The first direction, the second direction, and the third direction are arranged perpendicularly to each other.

3. The apparatus for observing the radiation characteristics of high-energy ion-matter interactions in the Bragg peak region according to claim 2, characterized in that, The first adjustment component includes: A pair of sliding table modules are arranged in parallel on the top surface of the transparent box. At least one pair of first sliders, each of the slide modules is provided with at least one first slider, the first sliders are partially connected to the support assembly, and the slide module is capable of driving the first sliders to move along the first direction.

4. The apparatus for observing the radiation characteristics of high-energy ion-matter interactions in the Bragg peak region according to claim 3, characterized in that, The support assembly includes: A pair of first supports are arranged in parallel, and the same side of the pair of first supports is connected to at least one of the first sliders on a slide module. The second bracket has two ends connected to a pair of the first brackets respectively; The third support is perpendicularly arranged and connected to the second support, and the third support is connected to the second adjustment component.

5. The apparatus for observing the radiation characteristics of high-energy ion-matter interactions in the Bragg peak region according to claim 4, characterized in that, The second bracket is provided with a first fixing hole, the first fixing hole having an inclined angle, the X-ray detector includes a first X-ray detector, and the first fixing hole is used to fix the first X-ray detector; The third bracket is provided with a second fixing hole, and the X-ray detector also includes a second X-ray detector. The second fixing hole is used to fix the second X-ray detector.

6. The apparatus for observing the radiation characteristics of high-energy ion-matter interactions in the Bragg peak region according to claim 4, characterized in that, The second adjustment component includes: A first base plate, wherein the platform is disposed on the first base plate; The first driver has two ends connected to the third bracket and the first base plate, respectively, and is used to drive the first base plate to move in the second direction.

7. The apparatus for observing the radiation characteristics of high-energy ion-matter interactions in the Bragg peak region according to claim 6, characterized in that, The third adjustment component includes: Second drive; The transmission structure is connected to the second driver; A base is disposed on the first base plate, and the base is rotatably connected to the transmission structure; The second slider is connected to the transmission structure, the stage is disposed on the second slider, and the second driver is used to drive the second slider to move along the third direction through the transmission structure.

8. The apparatus for observing the radiation characteristics of high-energy ion-matter interactions in the Bragg peak region according to claim 7, characterized in that, The transmission structure includes: A lead screw passes through the base and the second slider, and is rotatable relative to the base. When the lead screw rotates, it can drive the second slider to move. The rotating wheel is connected to the lead screw; A belt is fitted around the rotating wheel and the output shaft of the second driver to make them rotate synchronously.

9. The apparatus for observing the radiation characteristics of high-energy ion-matter interactions in the Bragg peak region according to claim 1, characterized in that, The beam shaping mechanism includes: An adapter is provided, which is connected to the transparent housing. The adapter is provided with a first through hole, which communicates with the interior of the transparent housing. A beam limiting block is connected to the adapter, and the beam limiting block is provided with a second through hole, which communicates with the first through hole; A beam de-energizer is connected to the beam limiting block, and the interior of the beam de-energizer communicates with the second through hole.

10. The apparatus for observing the radiation characteristics of high-energy ion-matter interactions in the Bragg peak region according to claim 1, characterized in that, Also includes: The second base plate, wherein the transparent box is disposed on the second base plate; Multiple adjusting members are arranged circumferentially along the second base plate, and the adjusting members are used to level the second base plate.

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