A multi-modal composite detection system for brain edema and brain oxygen
Through the multimodal composite detection system of cerebral edema and brain oxygen and electrical impedance detection, the problem of early diagnosis of ischemic stroke is solved, and the rapid and accurate identification of ischemic and hemorrhagic stroke is achieved to ensure that The patient is treated promptly during prime time, reducing the disability rate.
Patent Information
- Application Number
- CN202110349674.2
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- Filing Date
- 2021-03-31
- Publication Date
- 2024-12-20
- Estimated Expiration
- 2041-03-31
AI Technical Summary
The prior art is difficult to accurately diagnose ischemic stroke in the early stage, which often misses the golden time window during treatment. The bioelectrical impedance of ischemic stroke and hemorrhagic stroke is difficult to distinguish between low, medium and high frequency bands, and the detection accuracy is possible. Insufficient reliability.
Adopt brain edema and brain oxygen multimodal composite detection system, combined with cerebral blood oxygen content detection module and brain impedance detection module, through timing drive circuit, probe adapter, sending probe, receiving probe, signal generation circuit, frequency conversion circuit, differential signal The processing circuit and the sending and receiving electrode sets detect the bioelectrical impedance and cerebral blood oxygen saturation of the cranial brain, and obtain the initial state parameters through the control equipment, drive the probe adapter to run, calculate the cerebral blood oxygen saturation and cerebral blood oxygen saturation and cerebral blood oxygen saturation and cerebral blood oxygen saturation and cerebral blood oxygen saturation. Comprehensive identification of stroke categories.
It has achieved rapid and accurate distinction between ischemic and hemorrhagic stroke, improved the accuracy and credibility of diagnosis, ensured that patients were treated in a timely manner during the golden treatment time, and reduced the disability rate.
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Figure CN112932439B_ABST
Abstract
Description
Technical Field
[0001] The invention belongs to the technical field of medical detection, and in particular relates to a multi-modal composite detection system for cerebral edema and cerebral oxygen. Background Art
[0002] Stroke, also known as "stroke", is an acute cerebrovascular disease with a very high incidence, disability rate and mortality rate. It ranks first among all causes of death in my country, higher than cancer patients. Stroke is divided into ischemic stroke (cerebral infarction) and hemorrhagic stroke, with the former accounting for about 60-70%. The treatment plans for different types of stroke patients are completely different, so early identification of stroke types is of particular importance in saving patients' lives and reducing disability rates. For patients with ischemic stroke, if thrombolytic therapy can be performed within the time window (4-5 hours) after onset, it will play a decisive role in saving lives and reducing disability rates. It is very regrettable that due to the current diagnostic means of only CT and MRI, the proportion of ischemic stroke patients who can receive thrombolytic therapy in hospitals during this time window is only 8% in Western developed countries, and only 2.4% in my country. Ischemic stroke and hemorrhagic stroke patients are extremely similar in early symptoms, so it is difficult to distinguish them by observation alone. Usually, the patient has missed the golden treatment period after being sent to the hospital for diagnosis by imaging methods such as CT. Therefore, non-invasive, portable, real-time, early stroke diagnosis circuits and methods are eagerly awaited by the neurological medical community worldwide.
[0003] Electrical Impedance Tomography (EIT) is a non-invasive technology that reconstructs tissue images in vivo by targeting the distribution of electrical impedance inside the human body. The human body is a large bioelectric conductor, and each tissue and organ has a certain bioelectrical impedance. When a local organ of the human body is diseased, the impedance of the local part will inevitably change, which will interfere with the normal distribution of the external electric field in the body. Therefore, the pathological conditions of human tissues and organs can be detected, diagnosed and monitored by impedance measurement. In the part of the human body to be detected, a safe current (or voltage) is injected from the surface of the human body through electrodes, and then other electrodes (or the same electrodes) are used to measure the response voltage (or current) at different locations on the body surface, and the impedance distribution of different parts of the body can be calculated. Through simulation experiments, animal experiments, normal human testing and patient testing, as well as big data analysis, mathematical models and identification algorithms for corresponding different lesions such as tumors, hematomas, edema, and effusion in specific bioelectromagnetic field environments (such as the brain and chest) are constructed, which can assist in the identification and monitoring of the patient's condition.
[0004] The research of EIT technology has been going on for about 40 years both at home and abroad, and a lot of substantial progress has been made. Products such as "breast cancer diagnostic instrument", "pulmonary function tester" and "body composition analyzer" have been launched internationally. The research and application of EIT technology in the identification and differentiation of stroke types has a history of more than 20 years at home and abroad. However, because the bioimpedance of ischemic stroke patients is very close to that of normal human brain in the low, medium and high frequency bands, and there is only a difference in the ultra-low frequency band, the accuracy and credibility of the detection results of the existing EIT technology for the identification and differentiation of ischemic stroke patients are limited to a certain extent. Summary of the invention
[0005] The purpose of the present invention is to overcome the shortcomings of the prior art that it is difficult to conduct timely on-site detection of ischemic stroke patients and the detection results cannot be fully trusted, and a multi-modal composite detection system for cerebral edema and cerebral oxygen is proposed.
[0006] The present invention adopts the following technical solution:
[0007] A brain edema brain oxygen multi-modal composite detection system, the key of which is: comprising a brain blood oxygen content detection module and a brain electrical impedance detection module, the brain blood oxygen content detection module and the brain electrical impedance detection module are electrically connected to a control device respectively;
[0008] The cerebral blood oxygen content detection module includes a timing drive circuit, a detection head adapter, a transmitting probe and a receiving probe, wherein the timing drive circuit is electrically connected to the detection head adapter; the detection head adapter is electrically connected to the transmitting probe and the receiving probe respectively;
[0009] The brain electrical impedance detection module includes a signal generating circuit, a frequency conversion circuit, a differential signal processing circuit, a transmitting electrode group and a receiving electrode group, wherein the signal generating circuit, the frequency conversion circuit and the transmitting electrode group are electrically connected in sequence, and the receiving electrode group is electrically connected to the differential signal processing circuit;
[0010] The control device is electrically connected to the signal generating circuit, the frequency conversion circuit, the differential signal processing circuit, and the timing driving circuit respectively;
[0011] During detection, the transmitting electrode group and the receiving electrode group are respectively installed on both sides of the brain to be detected, and the transmitting probe and the receiving probe are both installed at the forehead of the brain to be detected;
[0012] The control device is used to control the brain electrical impedance detection module and the brain blood oxygen content detection module to perform bioelectrical impedance detection and brain blood oxygen saturation detection of the brain to be detected;
[0013] The control device is also used to obtain a pre-set initial state parameter in a brain edema and brain oxygen multi-modal composite detection system; and to send a driving instruction to the timing driving circuit according to the initial state parameter;
[0014] The timing drive circuit is used to drive and control the operation and data acquisition of the probe adapter according to the drive instruction issued by the control device; and obtain the data acquisition result of the probe adapter; and calculate the cerebral blood oxygen saturation according to the data acquisition result;
[0015] The detection head adapter is used to output a transmission electrical signal and convert the transmission electrical signal into a transmission optical signal, and control the transmission probe to transmit near-infrared light according to the transmission optical signal; and to control the receiving probe to receive the near-infrared light scattered back to the receiving probe; and to receive the recovery optical signal generated by the receiving probe and convert the recovery optical signal into a recovery electrical signal; and to form the data acquisition result according to the transmission electrical signal and the recovery electrical signal;
[0016] The transmitting probe is used to emit non-destructive low-density near-infrared light according to the transmitting light signal, and enter the skull and cerebral cortex through the probe on the patient's forehead;
[0017] The receiving probe is used to receive the near-infrared light scattered back to the receiving probe and form the recovered optical signal;
[0018] The signal generating circuit is used to generate an electromagnetic wave signal;
[0019] The frequency conversion circuit is used to adjust the frequency of the electromagnetic wave signal and output frequency conversion electromagnetic wave signals of different frequencies;
[0020] The transmitting electrode group inputs the variable frequency electromagnetic wave signal into the brain to be detected;
[0021] The receiving electrode group is used to receive the electromagnetic wave signal to be processed output by the brain to be detected;
[0022] The differential signal processing circuit is used to receive the electromagnetic wave signal to be processed and output a differential electromagnetic wave signal. The control device determines the bioelectrical impedance of the brain to be detected based on the differential electromagnetic wave signal. The control device is also used to comprehensively identify the stroke category of the brain to be detected through the bioelectrical impedance and cerebral blood oxygen saturation.
[0023] As a preferred solution, the detection head adapter includes an image detector and a photoelectric conversion circuit, the image detector is electrically connected to the timing drive circuit and the photoelectric conversion circuit respectively, and the photoelectric conversion circuit is also electrically connected to the transmitting probe and the receiving probe respectively;
[0024] The image detector is used to output the emission electrical signal according to the driving instruction; and to form the data acquisition result according to the recovery electrical signal transmitted by the photoelectric conversion circuit;
[0025] The photoelectric conversion circuit is used to convert the emission electrical signal into an emission light signal after gain adjustment; and to convert the recovery light signal into the recovery electrical signal and transmit it to the image detector.
[0026] As a preferred solution, the detector head adapter is used to control the emission and reception of near-infrared light of two different wavelengths, 850 nm and 730 nm.
[0027] As a preferred embodiment, the control device includes a data processing component, which is provided with preset brain data, and the preset data includes preset bioelectrical impedance and preset cerebral blood oxygen saturation. The control device identifies the stroke category of the brain to be detected by comparing the bioelectrical impedance detection and the cerebral blood oxygen saturation obtained with the preset brain data.
[0028] As a preferred solution, during detection, the transmitting probe is located at the center of the brain to be detected, and receiving probes are installed on both sides of the transmitting probe.
[0029] As a preferred solution, the signal generating circuit generates a plurality of the electromagnetic wave signals simultaneously, and the frequency conversion circuit adjusts the plurality of the electromagnetic wave signals into a plurality of the variable-frequency electromagnetic wave signals with different frequencies.
[0030] Beneficial effects: The brain edema and brain oxygen multimodal composite detection system of the present invention can simultaneously detect the bioimpedance and cerebral oxygen saturation of the patient's brain; detecting the patient's brain oxygen saturation can quickly distinguish between the normal brain and ischemic stroke; detecting the patient's brain bioimpedance can quickly identify whether it is a hemorrhagic stroke; effectively overcome the technical difficulty that the bioimpedance of ischemic stroke patients and the normal human brain impedance cannot be distinguished in the low, medium and high frequency bands, and the stroke type is comprehensively identified according to the bioimpedance and cerebral oxygen saturation detection results, which can achieve rapid and accurate identification, avoid misdiagnosis, and effectively grasp the patient's golden treatment time; ensure the patient's life safety and reduce the disability rate; and the sticking position of the brain oxygen detection in this scheme is the forehead, and the sticking position of the brain impedance detection is the skull wing point, the two signals do not overlap and do not interfere with each other, effectively ensuring the accuracy of stroke type identification. BRIEF DESCRIPTION OF THE DRAWINGS
[0031] Figure 1 It is a schematic diagram of the structure of a multi-modal composite detection system for cerebral edema and cerebral oxygen;
[0032] Figure 2The graphs are the changes of the conductivity of normal human brain tissue, ischemic stroke patient brain tissue and blood with frequency;
[0033] Figure 3 This is a comparison chart of the electrical conductivity and dielectric constant of common important brain tissues. DETAILED DESCRIPTION
[0034] The present invention is further described in detail below in conjunction with the accompanying drawings and embodiments:
[0035] Example: As shown in the attached Figure 1 As shown, a brain edema brain oxygen multi-modal composite detection system includes a brain blood oxygen content detection module and a brain electrical impedance detection module, and the brain blood oxygen content detection module and the brain electrical impedance detection module are electrically connected to the control device 100 respectively;
[0036] The cerebral blood oxygen content detection module includes a timing drive circuit 900, a detection head adapter 1000, a transmitting probe 1100 and a receiving probe 1200, wherein the timing drive circuit 900 is electrically connected to the detection head adapter 1000; the detection head adapter 1000 is electrically connected to the transmitting probe 1100 and the receiving probe 1200 respectively;
[0037] The brain electrical impedance detection module includes a signal generating circuit 200, a frequency conversion circuit 300, a differential signal processing circuit 500, a transmitting electrode group 600 and a receiving electrode group 700. The signal generating circuit 200, the frequency conversion circuit 300 and the transmitting electrode group 600 are electrically connected in sequence, and the receiving electrode group 700 is electrically connected to the differential signal processing circuit 500.
[0038] The control device 100 is electrically connected to the signal generating circuit 200, the frequency conversion circuit 300, the differential signal processing circuit 500, and the timing driving circuit 900 respectively;
[0039] During detection, the transmitting electrode group 600 and the receiving electrode group 700 are respectively installed on both sides of the brain 400 to be detected, the transmitting probe 1100 and the receiving probe 1200 are both installed on the forehead of the brain 400 to be detected, and the receiving probes 1200 are respectively installed on both sides of the transmitting probe 1100.
[0040] The control device 100 is used to control the brain electrical impedance detection module and the brain blood oxygen content detection module to perform bioelectrical impedance detection and brain blood oxygen saturation detection of the brain 400 to be detected;
[0041] The control device 100 is also used to obtain a pre-set initial state parameter in a brain edema and brain oxygen multi-modal composite detection system; and, according to the initial state parameter, issue a driving instruction to the timing drive circuit 900; the timing drive circuit 900 is used to drive and control the operation and data acquisition of the probe adapter 1000 according to the driving instruction issued by the control device 100; and, obtain the data acquisition result of the probe adapter 1000; and, calculate the cerebral blood oxygen saturation according to the data acquisition result;
[0042] The detection head adapter 1000 is used to output a transmission electrical signal and convert the transmission electrical signal into a transmission optical signal, and control the transmitting probe 1100 to transmit near-infrared light according to the transmission optical signal; and to control the receiving probe 1200 to receive the near-infrared light scattered back to the receiving probe 1200; and to receive the recovered optical signal generated by the receiving probe 1200 and convert the recovered optical signal into a recovered electrical signal; and to form the data acquisition result according to the transmission electrical signal and the recovered electrical signal;
[0043] The transmitting probe 1100 is used to emit non-destructive low-density near-infrared light according to the transmitting light signal, and enter the skull and cerebral cortex through the probe on the patient's forehead;
[0044] The receiving probe 1200 is used to receive the near-infrared light scattered back to the receiving probe 1200 and form the recovered optical signal;
[0045] The control device 100 includes a data processing component, which is provided with preset brain data, wherein the preset data includes preset bioelectrical impedance and preset cerebral blood oxygen saturation. The control device 100 identifies the stroke category of the brain 400 to be detected by comparing the bioelectrical impedance detection and the cerebral blood oxygen saturation obtained with the preset brain data.
[0046] During detection, the signal generating circuit 200 generates a plurality of electromagnetic wave signals simultaneously, and the frequency conversion circuit 300 adjusts the plurality of electromagnetic wave signals into a plurality of variable-frequency electromagnetic wave signals with different frequencies; the transmitting electrode group 600 inputs the plurality of variable-frequency electromagnetic wave signals into the brain to be detected 400;
[0047] The receiving electrode group 700 is used to receive the electromagnetic wave signal to be processed output by the brain to be detected 400; the differential signal processing circuit 500 is used to receive the electromagnetic wave signal to be processed and output a differential electromagnetic wave signal, and the control device 100 determines the bioelectrical impedance of the brain to be detected 400 according to the differential electromagnetic wave signal;
[0048] The detection head adapter 1000 includes an image detector 1010 and a photoelectric conversion circuit 1020. The image detector 1010 is electrically connected to the timing drive circuit 900 and the photoelectric conversion circuit 1020 respectively. The photoelectric conversion circuit 1020 is also electrically connected to the transmitting probe 1100 and the receiving probe 1200 respectively.
[0049] The image detector 1010 is used to output the emission electrical signal according to the driving instruction; and to form the data acquisition result according to the recovery electrical signal transmitted by the photoelectric conversion circuit 1020;
[0050] The photoelectric conversion circuit 1020 is used to convert the emission electrical signal into an emission light signal after gain adjustment; and to convert the recovery light signal into the recovery electrical signal and transmit it to the image detector 1010 .
[0051] Typically, the detector head adapter 1000 is used to control the emission and reception of near-infrared light of two different wavelengths, 850 nm and 730 nm.
[0052] In addition, in a specific implementation, in order to prevent damage to the patient's brain, a safety control device 800 electrically connected to the frequency conversion circuit 300 and the transmitting electrode group 600 may be provided between the two. The safety control device 800 is electrically connected to the control device 100. The preset brain data contains preset protection parameters. The safety control device 800 performs gain adjustment and filtering processing on the frequency conversion electromagnetic wave signal according to the protection parameters.
[0053] The safety control device 800 includes a filter adjustment circuit 810 and a transient suppression circuit 820, wherein the transient suppression circuit 820 is electrically connected to the filter adjustment circuit 810, the filter adjustment circuit 810 is electrically connected to the frequency conversion circuit 300, and the transient suppression circuit 820 is electrically connected to the transmitting electrode group 600 respectively;
[0054] The filter adjustment circuit 810 is used to perform gain adjustment and filter processing on the variable frequency electromagnetic wave signal according to the protection parameters, and the transient suppression circuit 820 is used to limit and suppress the variable frequency electromagnetic wave signal after gain adjustment and filtering processing to ensure that the patient is not harmed by the detected electromagnetic wave. The detection principle of this system:
[0055] (1) Detection principle of brain electrical impedance detection module:
[0056] Brain tissue is mainly composed of white matter, gray matter, blood and cerebrospinal fluid. Different tissue components have different electrical conductivity and dielectric constant (such as Figure 3As shown in Figure 2). Under the action of an applied AC electric field, the conductivity of white matter and gray matter does not change much, but the dielectric constant decreases sharply with increasing frequency; in addition, the conductivity and dielectric constant of cerebrospinal fluid and blood are relatively stable over a wide frequency range.
[0057] The brain impedance detection module uses a pair of electrodes to apply ultra-low AC electric fields of different frequencies to the brain tissue to stimulate it, polarize its dielectric, and measure its conduction current and displacement current, and then calculate the overall brain impedance (including phase) value. The brain impedance value of normal people is different from that of hemorrhagic stroke patients. Stroke patients usually have either hematoma (pathological feature of hemorrhagic stroke) or edema (pathological feature of ischemic stroke) in the skull. Hematoma and edema change the distribution of the external electric field in the skull, or change the performance of the electric field energy conduction pathway in the skull, that is, change the size of the conduction current and displacement current, thereby changing the brain impedance value. By detecting the brain impedance value, it can be quickly determined whether it is a hemorrhagic stroke. But from the attached Figure 2 It can be seen that the bioimpedance of ischemic stroke patients is very close to that of normal human brain impedance in the low, medium and high frequency bands, and only differs in the ultra-low frequency band. Therefore, it is not accurate enough to detect ischemic stroke patients only by the brain impedance detection module;
[0058] (2) Detection principle of cerebral blood oxygen content detection module:
[0059] Blood oxygen saturation (SaO 2 ) is the concentration of blood oxygen in the blood. Stroke patients either have pathological characteristics of edema or hematoma. Once the pathological characteristics occur, the patient's cerebral blood oxygen saturation will change. Detecting cerebral blood oxygen saturation can quickly distinguish whether the patient has a stroke. The cerebral blood oxygen content detection module emits non-destructive low-density near-infrared light, which enters the skull and cerebral cortex through the probe on the patient's forehead. The light source on the probe emits two near-infrared lights of different wavelengths. Part of the near-infrared light is scattered back to the forehead in a banana shape due to the refraction and scattering characteristics. There is a receiving point at 3 cm and 4 cm away from the light source to receive the near-infrared light scattered back to the probe. Because oxygenated hemoglobin and reduced hemoglobin have different absorption abilities for near-infrared lights of different wavelengths, the ratio of the absorption of two different wavelengths of near-infrared light can be calculated to obtain the ratio between oxygenated hemoglobin and reduced hemoglobin, and the blood oxygen saturation of the left and right brains can be measured in a very short time.
[0060] This solution places the cerebral blood oxygen detection on the forehead, and the brain electrical impedance detection on the skull wing. The two signals do not overlap and do not interfere with each other. The stroke category is comprehensively identified through bioelectrical impedance and cerebral blood oxygen saturation, which improves the accuracy of detection. Medical experiments have found that the identification accuracy of the present invention for hemorrhagic stroke patients can reach 94%, and the recall rate is increased by 94%; the identification accuracy of ischemic stroke patients can reach 95%, and the recall rate is increased by 96%. It undoubtedly provides great medical protection for the life safety of stroke patients.
[0061] Finally, it should be noted that the above description is only a preferred embodiment of the present invention. Under the guidance of the present invention, ordinary technicians in this field can make various similar expressions without violating the purpose and claims of the present invention, and such changes all fall within the scope of protection of the present invention.
Claims
1. A multi-modal composite detection system for cerebral edema and brain oxygen, characterized by: It comprises a brain blood oxygen content detection module and a brain electrical impedance detection module, wherein the brain blood oxygen content detection module and the brain electrical impedance detection module are electrically connected to the control device (100) respectively; The cerebral blood oxygen content detection module comprises a timing drive circuit (900), a detection head adapter (1000), a transmitting probe (1100) and a receiving probe (1200); the timing drive circuit (900) is electrically connected to the detection head adapter (1000); the detection head adapter (1000) is electrically connected to the transmitting probe (1100) and the receiving probe (1200) respectively; The brain electrical impedance detection module comprises a signal generating circuit (200), a frequency conversion circuit (300), a differential signal processing circuit (500), a transmitting electrode group (600) and a receiving electrode group (700); the signal generating circuit (200), the frequency conversion circuit (300) and the transmitting electrode group (600) are electrically connected in sequence, and the receiving electrode group (700) is electrically connected to the differential signal processing circuit (500); The control device (100) is electrically connected to the signal generating circuit (200), the frequency conversion circuit (300), the differential signal processing circuit (500), and the timing driving circuit (900) respectively; During detection, the transmitting electrode group (600) and the receiving electrode group (700) are respectively installed on both sides of the brain to be detected (400), and the transmitting probe (1100) and the receiving probe (1200) are both installed at the forehead of the brain to be detected (400); The control device (100) is used to control the brain electrical impedance detection module and the brain blood oxygen content detection module to perform bioelectrical impedance detection and brain blood oxygen saturation detection on the brain (400) to be detected; The control device (100) is also used to obtain an initial state parameter preset in a brain edema and brain oxygen multi-modal composite detection system; and to issue a driving instruction to the timing driving circuit (900) according to the initial state parameter; The timing drive circuit (900) is used to drive and control the operation and data collection of the detection head adapter (1000) according to the drive instruction issued by the control device (100); and to obtain the data collection result of the detection head adapter (1000); and to calculate the cerebral blood oxygen saturation according to the data collection result; The detection head adapter (1000) is used to output a transmission electrical signal and convert the transmission electrical signal into a transmission optical signal, and control the transmission probe (1100) to emit near-infrared light according to the transmission optical signal; and to control the receiving probe (1200) to receive the near-infrared light scattered back to the receiving probe (1200); and to receive a recovery optical signal generated by the receiving probe (1200) and convert the recovery optical signal into a recovery electrical signal; and to form the data acquisition result according to the transmission electrical signal and the recovery electrical signal; The transmitting probe (1100) is used to emit non-destructive low-density near-infrared light according to the emission light signal, and enter the skull and cerebral cortex through the probe on the patient's forehead; The receiving probe (1200) is used to receive the near-infrared light scattered back to the receiving probe (1200) and form the recovered optical signal; The signal generating circuit (200) is used to generate an electromagnetic wave signal; The frequency conversion circuit (300) is used to adjust the frequency of the electromagnetic wave signal and output frequency conversion electromagnetic wave signals of different frequencies; The transmitting electrode group (600) inputs the variable frequency electromagnetic wave signal into the brain to be detected (400); The receiving electrode group (700) is used to receive the electromagnetic wave signal to be processed output by the brain to be detected (400); The differential signal processing circuit (500) is used to receive the electromagnetic wave signal to be processed and output a differential electromagnetic wave signal, and the control device (100) determines the bioelectrical impedance of the brain (400) to be detected according to the differential electromagnetic wave signal; The control device (100) is also used to comprehensively identify the stroke category of the brain (400) to be detected through the bioelectrical impedance and cerebral blood oxygen saturation.
2. A multi-modal composite detection system for cerebral edema and brain oxygen according to claim 1, characterized in that: The detection head adapter (1000) comprises an image detector (1010) and a photoelectric conversion circuit (1020), wherein the image detector (1010) is electrically connected to the timing drive circuit (900) and the photoelectric conversion circuit (1020), respectively, and the photoelectric conversion circuit (1020) is also electrically connected to the transmitting probe (1100) and the receiving probe (1200), respectively; The image detector (1010) is used to output the emission electrical signal according to the driving instruction; and to form the data acquisition result according to the recovery electrical signal transmitted by the photoelectric conversion circuit (1020); The photoelectric conversion circuit (1020) is used to convert the emission electrical signal into an emission light signal after gain adjustment; and to convert the recovery light signal into the recovery electrical signal and transmit it to the image detector (1010).
3. A brain edema and brain oxygen multimodal composite detection system according to claim 1 or 2, characterized in that: The detection head adapter (1000) is used to control the emission and reception of near-infrared light of two different wavelengths, 850 nm and 730 nm.
4. A brain edema and brain oxygen multi-modal composite detection system according to claim 3, characterized in that: The control device (100) includes a data processing component, the data processing component is provided with preset brain data, the preset data includes preset bioelectrical impedance and preset cerebral blood oxygen saturation, and the control device (100) identifies the stroke category of the brain (400) to be detected by comparing the bioelectrical impedance detection and the cerebral blood oxygen saturation obtained by detection with the preset brain data.
5. The multi-modal composite detection system for cerebral edema and cerebral oxygen according to claim 1, characterized in that: During detection, the transmitting probe (1100) is positioned at the center of the skull (400) to be detected, and receiving probes (1200) are respectively installed on both sides of the transmitting probe (1100).
6. The multi-modal composite detection system for cerebral edema and cerebral oxygen according to claim 1, characterized in that: The signal generating circuit (200) generates a plurality of electromagnetic wave signals simultaneously, and the frequency conversion circuit (300) adjusts the plurality of electromagnetic wave signals into a plurality of frequency-converted electromagnetic wave signals having different frequencies.
