A semi-automatic sampling claw structure for freeze-drying medicine

By designing the lyophilized semi-automatic sampling claw structure for pharmaceuticals, the synchronous operation of the sampling clamp claw and the plugging rod is achieved, solving the problem of inability to press the bottle while taking out the drug bottle in the prior art, reducing the risk of drug contamination and improving the protection effect of drug quality.

CN113945408BActive Publication Date: 2025-03-28SHANGHAI TOFFLON SCI & TECH CO LTD
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Patent Information

Application Number
CN202111133175.6
Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
Filing Date
2021-09-27
Publication Date
2025-03-28
Estimated Expiration
2041-09-27

AI Technical Summary

Technical Problem

The existing lyophilized drug sampling structure cannot achieve blockage while removing the drug bottle, which increases the risk of drug contamination.

Method used

A lyophilized semi-automatic sampling jaw structure for pharmaceutical use is designed, including sampling jaws and plug rods. The clamping action link and plug action links are connected to the same push rod to achieve synchronous completion of clamping and plugging.

Benefits of technology

The synchronous operation of clamping and tamping the drug bottle in the drying box is achieved, reducing the risk of drug contamination and improving the protection effect of drug quality.

✦ Generated by Eureka AI based on patent content.

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Abstract

The present application discloses a semi-automatic sampling claw structure for freeze-drying machine medicine, characterized in that it comprises a sampling claw for clamping a medicine bottle and a plugging rod for plugging the rubber plug at the mouth of the medicine bottle; the sampling claw and the plugging rod are respectively connected to the same push rod via a clamping action connecting rod and a plugging action connecting rod; the movement of the push rod drives the sampling claw and the plugging rod to synchronously complete the clamping action and the plugging action. The advantage of the present application is that it can perform plugging processing while satisfying the clamping, and realizes that the clamping and plugging are completed in one step inside the box, reducing the risk of drug contamination.
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Description

Technical Field

[0001] The present application relates to a semi-automatic sampling claw structure for freeze-drying medicines, and belongs to the technical field of freeze-drying medicine sampling structures. Background Art

[0002] The drug sampling structure of the freeze-drying machine is mostly used in the field of early process development of new drugs. As the current market demand for new drugs is increasing, it is also very important for the development of new drugs and early testing of drugs. During the whole process of freeze-drying of new drugs, it is necessary to continuously take out the drugs from the drying box at various stages for observation and research, and the quality of the drugs also needs to be strictly protected during this process. The drugs need to be plugged in the drying box before they can be taken out, so as to ensure that the drugs are not contaminated by the outside world. The process involves two actions: plugging and taking out. The current sampling claws can only realize the taking out action, resulting in the need to use different instruments for plugging and taking out, which increases the possibility of drug contamination; therefore, it is particularly important to choose a suitable sampling claw to clamp the drug bottle. Summary of the invention

[0003] The technical problem to be solved by the present application is how to achieve plugging while taking out the medicine bottle.

[0004] In order to solve the above technical problems, the technical solution of the present application is to provide a semi-automatic sampling claw structure for freeze-drying machine medicine, characterized in that:

[0005] It includes a sampling clamping claw for clamping a medicine bottle and a plugging rod for plugging a rubber plug at the mouth of the medicine bottle;

[0006] The sampling clamping claw and the plug pressing rod are connected to the same push rod via a clamping action connecting rod and a plug pressing action connecting rod respectively;

[0007] The movement of the push rod drives the sampling clamping claw and the plugging rod to synchronously complete the clamping action and the plugging action, thereby achieving synchronous completion of clamping and plugging.

[0008] Preferably, the sampling claw comprises a right sampling claw and a left sampling claw, the front ends of the right sampling claw and the left sampling claw are working ends for clamping the medicine bottle; the middle parts of the right sampling claw and the left sampling claw are hinged to form the sampling claw; the rear ends of the right sampling claw and the left sampling claw are connected to the push rod through a sampling claw connecting rod.

[0009] Preferably, a sampling claw hinge shaft is provided at the middle hinged part of the right sampling claw and the left sampling claw, and the sampling claw hinge shaft is set as the rotation axis for the right sampling claw and the left sampling claw to realize the clamping action.

[0010] Preferably, a plugging wheel is provided at the front end of the plugging rod for performing the plugging action, and during the plugging action, the plugging wheel and the rubber plug are in rolling contact to reduce friction.

[0011] Preferably, the middle portion of the plug pressing rod is hinged to the end of the hinge shaft of the sampling claw, and the rear end of the plug pressing rod is connected to the push rod via a plug pressing connecting rod.

[0012] Preferably, the push rod outer sleeve is provided with a sampling rod sealing shell, the push rod and the sampling rod sealing shell are slidably connected, a lubricating sleeve is provided between them, and a sealing O-ring is also provided between the push rod and the sampling rod sealing shell. The push rod is used as a dividing line, the sampling claw structure located at the rear end of the push rod is the non-sterile section, and the sampling claw structure located at the front end of the push rod is the sterile section, which separates the sterile section and the non-sterile section. The sterile section of the sampling claw structure can enter the interior of the box as a whole to perform clamping and plugging actions, and the non-sterile section is located outside for manipulation.

[0013] Preferably, a bracket is provided at the front of the sampling rod sealing shell for fixing and supporting the sampling claw hinge shaft; a cushion seat is provided on the bracket for isolating the right sampling claw, the left sampling claw and the bracket to avoid friction.

[0014] Preferably, the push rod sleeve is provided with a compression spring, one end of the compression spring is connected to the push rod, and the other end is connected to the sampling rod sealing shell; the compression spring continuously provides elastic force to push the push rod to maintain the clamping state of the sampling clamp.

[0015] Preferably, the rear end of the sampling rod sealing shell away from the medicine bottle is connected to the sampling outer rod, and the sampling outer rod and the sampling rod sealing shell are welded and fixed; the rear end of the push rod is connected to a wire drawing for extending the operating distance, and the wire drawing is pulled to control the movement of the push rod, and when the wire drawing is pulled backward, the push rod moves backward, driving the sampling claw to release, and the sampling claw structure can be moved to another medicine bottle. After the sampling claw is aligned with the medicine bottle, the wire drawing is released, and the sampling claw automatically clamps the medicine bottle, thereby realizing semi-automatic clamping.

[0016] The advantage of the present application is that it can perform plugging while satisfying the clamping function, so that the clamping and plugging can be completed in one step inside the box, reducing the risk of drug contamination and realizing the important attribute of semi-automatic clamping and plugging. BRIEF DESCRIPTION OF THE DRAWINGS

[0017] Figure 1 It is a schematic diagram of the structure of the sampling claw provided in the embodiment;

[0018] Figure numerals: medicine bottle 1, right sampling claw 2, left sampling claw 3, plug pressing wheel 4, sampling claw hinge shaft 5, plug pressing rod 6, plug pressing connecting rod 7, push rod 8, sampling rod sealing shell 9, lubricating sleeve 10, cushion seat 11, pin 12, O-ring 13, compression spring 14, sampling outer rod 15, drawing 16, rubber plug 17, sampling claw connecting rod 18. DETAILED DESCRIPTION

[0019] In order to make the present application more clear and understandable, a preferred embodiment is described in detail as follows with reference to the accompanying drawings.

[0020] Example

[0021] This embodiment provides a semi-automatic sampling claw structure for freeze-drying machine medicine, which can realize the pressing of the rubber stopper while taking out the medicine bottle. The sampling claw is made into a structure that integrates clamping and plugging, and can also perform plugging work while clamping. The whole process is completed in the drying box, ensuring the structure and quality properties of the medicine;

[0022] Structure Figure 1 As shown, the medicine bottle 1 is used to hold medicines; the right sampling claw 2 and the left sampling claw 3 are hinged in the middle to form a sampling claw for clamping the medicine bottle 1; the front ends of the right sampling claw 2 and the left sampling claw 3 are working ends for clamping the medicine bottle 1, and the shapes are both set to be arc-shaped to match the outer contour of the medicine bottle 1;

[0023] The plugging wheel 4 is arranged on the sampling clamping claw, and is located just above the medicine bottle 1. It is used to plug the rubber plug 17 while clamping the medicine. The roller can roll on the rubber plug to reduce the friction and lateral thrust on the rubber plug; the sampling claw hinge shaft 5 is a rotating shaft used to connect the right sampling claw 2 and the left sampling claw 3; the plugging wheel 4 is installed on the front end of the plugging rod 6 close to the medicine bottle 1, and the middle part of the plugging rod 6 is hinged to the end of the sampling claw hinge shaft 5, so that the front end of the plugging rod 6 swings up and down to drive the plugging wheel 4 to move up and down for plugging the rubber plug 17. The plugging rod 6 is hinged to the front end of the plugging connecting rod 7 at the rear end away from the medicine bottle. The plugging connecting rod 7 serves as a power input and is used to push the plugging rod 6 to realize the up and down swing of the front end of the plugging rod 6;

[0024] The rear ends of the right sampling claw 2 and the left sampling claw 3 away from the working end are hinged to the sampling claw connecting rod 18, and the rear ends of the plugging connecting rod 7 and the sampling claw connecting rod 18 are hinged to the push rod 8. The push rod 8, the sampling claw connecting rod 18, and the sampling clamping claw form a clamping action component, and the push rod 8, the plugging connecting rod 7, the plugging rod 6, and the compression wheel 4 form a plugging action component. The push rod 8 realizes unified action input, and the clamping action and the plugging action are synchronously integrated.

[0025] Taking the push rod 8 as the dividing line, the rear end of the push rod 8 is the non-sterile area and the front end is the sterile area. The sterile and non-sterile areas need to be separated. The sampling rod sealing shell 9 is used to seal the push rod 8. The sealing push rod 8 slides back and forth in the sampling rod sealing shell 9. A lubricating sleeve 10 is installed between the push rod 8 and the sampling rod sealing shell 9 to facilitate lubrication and support of the push rod 8. The O-ring 13 is used to seal the push rod 8; the sampling rod sealing shell 9 extends forward with a bracket to fix and support the sampling claw hinge shaft 5, which plays the role of supporting the clamping action component and the plugging action component. The forward bracket of the sampling rod sealing shell 9 is provided with a cushion seat 11, which is used to isolate the right sampling claw 2, the left sampling claw 3 and the forward bracket of the sampling rod sealing shell 9 to avoid friction; one end of the compression spring 14 is connected to the push rod 8 and the other end is connected to the sampling rod sealing shell 9. Under the thrust of the compression spring 14, the sampling claw is closed, the plugging rod will be pressed down, and the rubber plug will be pressed on;

[0026] The rear end of the sampling rod sealing shell 9 is connected to the sampling outer rod 15, and the sampling outer rod 15 and the sampling rod sealing shell 9 are welded together to move and fix the entire sampling claw structure; the rear end of the push rod 8 is connected to the drawing wire 16, and the drawing wire 16 is pulled to control the movement of the push rod 8. The drawing wire 16 is set in the inner cavity of the sampling outer rod 15. The drawing wire 16 can extend the operating distance. The drawing wire 16 pulls the push rod 8, drives the sampling claw to open, and takes out the plugged bottle from a specific sampling port.

[0027] The working process of the semi-automatic sampling claw structure provided by the present application is that the compression spring 14 provides rebound force and maintains the thrust of the push rod 8, the sampling claw remains clamped, the compression wheel 4 remains in a low position, the wire drawing 16 is pulled backward, and the push rod 8 is driven to move backward, the sampling claws are separated, and the compression wheel 4 is raised under the drive of the plug pressing rod 6, and the semi-automatic sampling claw structure is moved to the medicine bottle 1 to be clamped, the sampling claw is aligned with the medicine bottle 1, and the compression wheel 4 is aligned with the bottle mouth plug 17, the wire drawing 16 is released, and the push rod 8 is pushed forward under the push of the compression spring 14, and the sampling claw clamps the medicine bottle 1 through the transmission of the clamping action component and the plug pressing action component to realize semi-automatic sampling, and the compression wheel 4 presses the plug 17 to realize the synchronous completion of clamping and plugging.

[0028] The above structure is used as a semi-automatic sampling claw structure for freeze-drying medicines, which can complete the clamping and plugging work inside the drying box, ensuring zero external contamination of the medicines.

Claims

1. A semi-automatic sampling claw structure for freeze-drying machine medicine, characterized in that: It includes a sampling clamping claw for clamping a medicine bottle and a plugging rod for plugging a rubber plug at the mouth of the medicine bottle; The sampling clamping claw and the plug pressing rod are connected to the same push rod via the sampling claw connecting rod and the plug pressing connecting rod respectively; It also includes a sampling claw hinge shaft for the sampling claw to realize its clamping action, the middle part of the plug pressing rod is hinged with the end of the sampling claw hinge shaft, the rear end of the plug pressing rod is connected to the push rod through the plug pressing connecting rod, and the push rod sleeve is provided with a compression spring; The movement of the push rod drives the sampling clamping claw and the plugging rod to synchronously complete the clamping action and the plugging action; the sampling clamping claw comprises a right sampling claw and a left sampling claw, the front ends of the right sampling claw and the left sampling claw are working ends for clamping the medicine bottle; the middle parts of the right sampling claw and the left sampling claw are hinged to form the sampling clamping claw; the rear ends of the right sampling claw and the left sampling claw are connected to the push rod through the sampling claw connecting rod; A sampling claw hinge shaft is provided at the hinged middle part of the right sampling claw and the left sampling claw, and the sampling claw hinge shaft is set as a rotating shaft for the right sampling claw and the left sampling claw to realize the clamping action; A plugging wheel is arranged at the front end of the plugging rod for performing the plugging action. During the plugging action, the plugging wheel and the rubber plug are in rolling contact to reduce friction.

2. The semi-automatic sampling claw structure for freeze-drying machine medicine according to claim 1, characterized in that: The push rod outer sleeve is provided with a sampling rod sealing shell, the push rod and the sampling rod sealing shell are slidably connected, a lubricating sleeve is provided between the push rod and the sampling rod sealing shell, and a sealing O-ring is also provided between the push rod and the sampling rod sealing shell.

3. The semi-automatic sampling claw structure for freeze-drying medicine according to claim 2, characterized in that: The sampling rod sealing shell is provided with a bracket extending forward to fix and support the sampling claw hinge shaft; a cushion seat is provided on the bracket to isolate the right sampling claw, the left sampling claw and the bracket to avoid friction.

4. The semi-automatic sampling claw structure for freeze-drying medicine according to claim 3, characterized in that: The push rod sleeve is provided with a compression spring, one end of the compression spring is connected to the push rod, and the other end is connected to the sampling rod sealing shell.

5. The semi-automatic sampling claw structure for freeze-drying medicine according to claim 4, characterized in that: The rear end of the sampling rod sealing shell away from the medicine bottle is connected to the sampling outer rod, and the sampling outer rod and the sampling rod sealing shell are welded and fixed; the rear end of the push rod is connected to a wire drawing for extending the operating distance, and the wire drawing is pulled to control the movement of the push rod.

Citation Information

Patent Citations

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