Tissue glue application device

By designing a tissue glue application device with a dual injection assembly and a mixer, instant mixing and rapid application of powder and liquid is achieved, solving the problems of inconvenient configuration and contamination of tissue glue in the prior art, and meeting the needs of immediate use in surgery.

CN114177510BActive Publication Date: 2025-08-12BEIJING BIOSIS HEALING BIOLOGICAL TECH CO LTD
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Patent Information

Application Number
CN202111674659.1
Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
Filing Date
2021-12-31
Publication Date
2025-08-12
Estimated Expiration
2041-12-31

AI Technical Summary

Technical Problem

In the prior art, tissue glue is difficult to use immediately after configuration, and the configuration process is easily contaminated, resulting in the inability to apply in time during surgery.

Method used

A tissue glue application device is designed, using a dual injection assembly and a mixer. Through the cooperation of the slide column and the push rod, instant mixing and injection of powder and liquid is achieved, ensuring that the liquid levels are fully mixed and reacted with each other and quickly applied.

Benefits of technology

Realize the instant generation and rapid application of tissue glue, avoid the risk of contamination during the configuration process, and meet the needs of immediate use during surgery.

✦ Generated by Eureka AI based on patent content.

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Abstract

The present disclosure provides a tissue glue application device, which includes: two injection assemblies and a mixer; the two injection assemblies are connected to the mixer through an injection port; each injection assembly includes: an injection shell, a slide column and a push rod; the slide column is inserted into the injection shell from the opening and can slide along the injection shell; the two ends of the slide column are respectively an insertion end and a push-pull end; the insertion end is located in the injection shell, and the push rod is installed on the push-pull end; a liquid inlet hole is provided on the insertion end; a plug for sealing the liquid inlet hole is provided on the push rod; the push rod slides relative to the cavity so that the plug opens the liquid inlet hole and the injection shell and the cavity are connected through the liquid inlet hole. The present disclosure uses two injection assemblies to respectively store a variety of tissue glue raw materials, and can use the sliding action of the push rod to open the liquid inlet hole to mix the powder with the liquid to generate tissue glue, thereby facilitating the immediate production and use of tissue glue, and achieving the advantages of sufficient mixing and reaction of the liquid levels and rapid application.
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Description

Technical Field

[0001] The present disclosure relates to medical device manufacturing technology, and in particular to a tissue glue applying device, belonging to the technical field of medical product manufacturing. Background Art

[0002] Medical glue is an emerging medical product that replaces sutures. Its main ingredient is a-cyanoacrylate, which polymerizes rapidly in biological tissue. Under the influence of anions in the blood and tissue fluid at the wound surface, the glue rapidly polymerizes and solidifies into a film that adheres tightly to the wound surface, firmly maintaining the wound in place. The film also blocks the passage of blood cells and platelets. With the combined action of thrombin and fibrinogen, it seals broken small blood vessels in the wound, effectively stopping bleeding. The film also isolates tissue from bacteria, providing resistance to infection and wound protection. The ether chains in the polymer also have analgesic properties, resulting in medical glue possessing comprehensive benefits including adhesion, hemostasis, analgesia, anti-inflammatory, wound care, and healing promotion.

[0003] Medical tissue glue is a tissue adhesive used to bond human tissues. It can be directly applied or sprayed on wounds or wound surfaces for wound healing. Medical hydrogel, as a type of tissue glue, is a new type of functional polymer material. It has hydrophilic groups and is a polymer with a three-dimensional network structure that can be swollen by water but is insoluble in water. It has the characteristics of biosafety, modifiability, modifiability, and good mechanical properties. It has a wide range of applications in biomedicine, agriculture, industry, environmental protection and other fields. In the biomedical field, hydrogel can be used as a medical dressing to cover wounds and achieve rapid healing. In addition, hydrogel can also be used as a drug sustained-release carrier, tissue engineering material, oral application material, etc. Due to its porosity, softness, high water content, and high tissue compatibility, it has very broad application prospects in the biomedical field. At present, there are many hydrogel materials on the market that are used in clinical hemostasis and sealing.

[0004] Medical hydrogels have a wide range of applications, including application to various wounds, both on the surface and inside the body. Existing techniques primarily utilize dual syringes for hydrogel application, but for wounds inside the body, particularly those used in laparoscopic surgery, application of hydrogels is difficult.

[0005] Tissue glues, such as medical hydrogels, require liquid-level mixing after the solid and liquid components are mixed to ensure complete and uniform gelation. This thorough mixing results in a rapid reaction rate, requiring the hydrogel to be applied promptly to the tissue being treated. This places high demands on existing applicators. Therefore, when applying tissue glue, such as for wound coating, a ready-to-use approach is required.

[0006] Tissue glue in the existing technology is generally prepared in advance before surgery and then used; however, due to the large number of preparation components, the preparation time is very long, and there is often no time to prepare it when it is needed; if prepared in advance, the prepared gel is easily contaminated if left for a long time, which creates risks when used. Summary of the Invention

[0007] The present disclosure provides a new tissue glue application device, which can immediately prepare and inject tissue glue by arranging a sliding cavity in the injection component that can mix solid and liquid to generate gel, thereby solving the technical problem in the prior art that tissue glue cannot be used immediately after being prepared.

[0008] The tissue glue application device of the embodiment of the present disclosure comprises: two injection assemblies and a mixer; the two injection assemblies are fixedly connected to each other and each has an injection port; the two injection ports are both connected to the mixer;

[0009] Each of the injection assemblies comprises an injection housing, a slide column and a push rod; the injection housing is a cylindrical structure with an opening at one end and an injection port at the other end; the slide column is inserted into the injection housing through the opening and can slide along the injection housing;

[0010] The slide column has a tubular cavity, and the two ends of the slide column are respectively an insertion end and a push-pull end; the insertion end is located in the injection housing, and the push rod is installed on the push-pull end; one end of the push rod is located in the cavity and can slide along the length direction of the cavity;

[0011] A liquid inlet hole is provided on the insertion end; a plug for sealing the liquid inlet hole is provided on the push rod; the push rod slides relative to the cavity so that the plug opens the liquid inlet hole and the interior of the injection shell and the cavity are connected through the liquid inlet hole.

[0012] In some embodiments, the push rods on the two injection assemblies are parallel to each other.

[0013] In some embodiments, the device further comprises: a connecting fixing frame and a pull ring; the two injection assemblies are fixed on the connecting fixing frame in parallel with each other;

[0014] Pressing handles are symmetrically provided on both sides of the connecting fixing frame, and the push rods on the two injection assemblies are fixed on the pull ring.

[0015] In some embodiments, a limiting rod is further provided on the connecting and fixing frame; one end of the limiting rod is fixed to the connecting and fixing frame, and the other end abuts against the pull ring.

[0016] In some embodiments, a liquid inlet groove is provided on the push rod; when the plug opens the liquid inlet hole, the liquid inlet groove establishes a liquid flow channel at the liquid inlet hole.

[0017] In some embodiments, the slide column slides on the inner wall of the injection housing through the sealing plug.

[0018] In some embodiments, a sliding hole is provided on the push-pull end, and the push rod slides in the cavity through the sliding hole; an air inlet groove is provided on the push rod, and when the plug opens the liquid inlet hole, the air inlet groove establishes a gas flow channel at the sliding hole.

[0019] In some embodiments, each of the injection ports is provided with a switch valve, and each of the injection ports is connected to the mixer via the switch valve.

[0020] In some embodiments, the mixer is a Y-shaped mixer having an output port and two input ports that are interconnected; the mixer is connected to the two injection ports respectively through the two input ports;

[0021] The output port is provided with a nozzle, and the nozzle is preferably an atomizer.

[0022] In some embodiments, the switch valve is a one-way valve.

[0023] In the disclosed embodiment, two injection assemblies are used to store a variety of tissue glue raw materials respectively. The sliding action of the push rod can be used to open the liquid inlet hole to mix the powder and liquid to generate tissue glue, thereby facilitating the immediate production and use of tissue glue, achieving the advantages of sufficient mixing and reaction of liquid levels and rapid application.

[0024] The tissue glue application device disclosed in the present invention adopts a sliding column of a double injection assembly to accommodate two tubes of different liquids, and correspondingly adopts multiple injection shells to store different types of solutes. All raw materials are separated from each other, which is conducive to the preservation of the materials that form the tissue glue. The mixing effect of the liquid and the container is achieved by switching the liquid inlet hole at the end of the sliding column and the injection shell. The present invention distinguishes the process of mixing liquids with liquids separately from the process of mixing the liquids in the double injection assembly into hydrogels, and further directly applies the mixed liquid after it passes through the mixer. The tissue glue is used as soon as it is formed, which realizes the advantages of sufficient reaction of the liquid-level mixing and rapid application. BRIEF DESCRIPTION OF THE DRAWINGS

[0025] In order to more clearly illustrate the embodiments of the present disclosure or the technical solutions in the prior art, a brief introduction will be given below to the drawings required for use in the embodiments or the description of the prior art. Obviously, the drawings described below are some embodiments of the present disclosure. For ordinary technicians in this field, other drawings can be obtained based on these drawings without any creative work.

[0026] Figure 1 is a structural diagram of a tissue glue applying device according to an embodiment of the present disclosure;

[0027] Figure 2 is a cross-sectional structural diagram of a tissue glue applying device according to an embodiment of the present disclosure;

[0028] Figure 3 This is a cross-sectional structural diagram from another angle of the tissue glue applying device according to an embodiment of the present disclosure. DETAILED DESCRIPTION

[0029] To make the objectives, technical solutions, and advantages of the present disclosure more clear, the present disclosure will be further described in detail below with reference to the accompanying drawings. It is apparent that the embodiments described are only a portion of the embodiments of the present disclosure, rather than all of them. All other embodiments derived by persons of ordinary skill in the art based on the embodiments of the present disclosure without creative effort are intended to fall within the scope of protection of the present disclosure.

[0030] The terms used in the embodiments of the present disclosure are for the purpose of describing specific embodiments only and are not intended to limit the present disclosure. The singular forms "a," "an," "the," and "the" used in the embodiments of the present disclosure and the appended claims are also intended to include plural forms, and unless the context clearly indicates otherwise, "a plurality" generally includes at least two.

[0031] It should be understood that the term "and / or" as used herein is merely a description of the relationship between associated objects, indicating that three possible relationships exist. For example, "A and / or B" can represent: A exists alone, A and B exist simultaneously, or B exists alone. Furthermore, the character " / " in this document generally indicates that the associated objects are in an "or" relationship.

[0032] It should also be noted that the terms "include," "comprises," or any other variations thereof are intended to encompass non-exclusive inclusion, such that a product or device comprising a series of elements includes not only those elements but also other elements not explicitly listed, or elements inherent to such product or device. In the absence of further limitations, an element defined by the phrase "comprising a" does not exclude the presence of other identical elements in the product or device comprising the element.

[0033] In the art, tissue glues, such as medical hydrogels, require liquid-level mixing after mixing the solid and liquid components to ensure complete and uniform gelation. This thorough mixing process results in a rapid reaction rate, necessitating prompt application of the hydrogel to the tissue being treated, placing high demands on the applicator. Consequently, tissue glue applications, such as wound coating, require a ready-to-use approach.

[0034] The present disclosure provides a tissue glue applying device, comprising: two injection assemblies and a mixer; the two injection assemblies are fixedly connected to each other and each have an injection port; the two injection ports are connected to the mixer; each injection assembly comprises: an injection shell, a slide column and a push rod; the injection shell is a cylindrical structure with an opening at one end and the injection port at the other end; the slide column is inserted into the injection shell from the opening and can slide along the injection shell; the slide column has a tubular structure, and the two ends of the slide column are respectively an insertion end and a push-pull end; the insertion end is located in the injection shell, and the push rod is installed on the push-pull end; one end of the push rod is located in the cavity and can slide along the length direction of the cavity; a liquid inlet hole is provided on the insertion end; a plug for sealing the liquid inlet hole is provided on the push rod; the push rod slides relative to the cavity so that the plug opens the liquid inlet hole and the interior of the injection shell and the cavity are connected through the liquid inlet hole.

[0035] The working principle of the tissue glue application device disclosed in the present invention is as follows: the sliding column of the double injection assembly is used to respectively accommodate two tubes of liquid, and two injection shells are correspondingly used to store different types of solutes, and two independent sets of structures are used to form the liquid to be mixed to form the tissue glue. All raw materials are separated from each other, which is conducive to the preservation of the materials that form the tissue glue. The mixing effect of the liquid and the solute is achieved by switching the liquid inlet hole at the end of the sliding column and the injection shell. The present invention distinguishes the process of mixing liquids separately from the process of mixing the liquids in the double injection assembly into hydrogels, and further directly applies the mixed liquid after it passes through the mixer. The tissue glue is used as soon as it is formed, which realizes the advantages of sufficient reaction of the liquid-level mixing and rapid application.

[0036] The tissue glue application device disclosed herein can be made of, but not limited to, the following materials and components, such as: rubber stoppers, silicone, plastic, nylon, polytetrafluoroethylene, one-way valves, atomizing nozzles, lead-free glass, plastic brackets, limit devices, etc.

[0037] like Figure 1 The structure diagram of the tissue glue applying device of the embodiment of the present disclosure is shown; Figure 2 and Figure 3 .

[0038] The tissue glue application device of the embodiment of the present disclosure includes: two injection components and a mixer 6; the two injection components are fixedly connected to each other and both have injection ports; the two injection ports are connected to the mixer 6; each injection component is used to mix and produce a mixed liquid, and the two mixed liquids are mixed again through the mixer 6 to form the required tissue glue.

[0039] Further, such as Figure 2 As shown, each injection port is provided with a switch valve 10 , and each injection port is connected to the mixer 6 via the switch valve 10 .

[0040] Typically, in order to prevent the generated mixed liquid from flowing back, the switch valve 10 is a one-way valve.

[0041] Preferably, the mixer 6 is a Y-shaped mixer having an output port and two input ports that are interconnected; the mixer 6 is connected to the two injection ports respectively through the two input ports; a nozzle 60 is provided on the output port, which can be a liquid nozzle or an atomizer. The nozzle 60 allows the tissue glue output by the tissue glue application device to be sprayed out, thereby improving the utilization efficiency of the tissue glue. The atomizer is generally a Venturi tube atomizer. When the gas or liquid flows inside the Venturi tube, the dynamic pressure reaches a maximum value and the static pressure reaches a minimum value at the narrowest point of the pipe, and the speed of the gas (liquid) increases due to the reduction in the cross-sectional area of the flow. The entire flow must undergo the process of pipe shrinkage at the same time, so the pressure also decreases at the same time. This generates a pressure difference, which is used to provide an external suction force for the fluid, thereby forming an atomization effect. The Venturi tube atomizer has a simple structure and good use effect.

[0042] like Figure 1 Each of the injection components includes: an injection shell 1, a slide column 2 and a push rod 3; the injection shell 1 is used to hold and seal the solute, and can also hold the mixed liquid during the injection process of the mixed liquid; the slide column 2 is also a closed structure, used to seal and store the liquid that generates the mixed liquid.

[0043] Because two sets of injection components are used, two different solutes and different liquids can be included, and the four components can be stored independently.

[0044] Figure 2 This is a cross-sectional structural diagram of the tissue glue application device according to an embodiment of the present disclosure. The injection housing 1 is a cylindrical structure with an opening at one end and an injection port at the other end. The slide 2 is inserted into the injection housing 1 through the opening and can slide along the injection housing 1. The slide 2 squeezes the space within the injection housing, thereby enabling the injection housing 1 to achieve the injection effect. The two slides 2 are fixedly connected to each other by a connecting bracket 8 and move synchronously.

[0045] One end of the slide 2 is used to slide in the injection housing 1 to compress the material in the injection housing 1 and move it toward the injection port to achieve the injection effect. In other words, the slide is equivalent to the piston of the injection housing, mainly used to compress the volume in the injection housing 1 to achieve the injection effect.

[0046] The slide column 2 is a tubular cavity, the two ends of which are an insertion end and a push-pull end respectively; the insertion end is located in the injection housing 1, and the push rod 3 is installed on the push-pull end; one end of the push rod 3 is located in the cavity and can slide along the length direction of the cavity; the slide column 2 is also a closed cavity, and the push rod 3 is used to open the closed cavity.

[0047] Figure 3 The push rod 3 is only used to open or close the liquid inlet 22 at the insertion end through axial movement, thereby achieving communication between the injection housing 1 and the interior of the slide column 2.

[0048] A liquid inlet hole 22 is provided on the insertion end of the slide column 2; a plug 30 for sealing the liquid inlet hole 22 is provided on the push rod 3; the push rod 3 slides relative to the cavity so that the plug 30 opens the liquid inlet hole 22 and the injection housing 1 and the cavity are connected through the liquid inlet hole 22.

[0049] The mixing process of the tissue glue application device of the present disclosure embodiment is as follows:

[0050] Take out the tissue glue application device disclosed in the present invention; in the two injection components, the injection shell 1 is filled with a solute as the injection shell, and the slide column 2 is sealed with liquid. At this time, the end of the push rod 3 is located at the liquid inlet hole 22 to seal the liquid inlet hole 22; a radial sealing or axial abutment sealing structure can be adopted between the push rod 3 and the liquid inlet hole 22. For example, a plug 30 for sealing can be provided at the front end of the push rod 3 to facilitate axial opening of the liquid inlet hole 22. At the same time, a liquid inlet groove 31 is provided on the cylindrical radial surface of the push rod 3. When the plug 30 opens the liquid inlet hole 22, the liquid inlet groove 31 corresponds to the liquid inlet hole 22, thereby establishing a connection between the cavity of the slide column and the internal cavity of the injection shell 1; at this time, the push rod passes through the liquid inlet hole 22, and has a radial gap with the liquid inlet hole 22, which is formed by the liquid inlet groove 31. In addition, an air inlet groove 32 can be provided on the side of the push rod 3 at the push-pull end. When the air inlet groove 32 is located at the slide hole 21 at the push-pull end, the slide hole 21 can be opened, establishing a channel for external air to enter the slide column. At this time, the push rod 3 and the pull ring are kept stationary to keep the liquid inlet hole open, and the two slide columns 2 are pulled to the right. As the air pressure in the slide columns 2 decreases, air is sucked into the slide columns 2 from the slide hole 21 at the push-pull end. At the same time, the volume in the injection housing 1 increases. Due to the action of the one-way valve 10, a negative pressure is formed in the injection housing 1, and the liquid in the slide column 2 quickly flows into the injection housing 1 through the liquid inlet hole 22. At this time, the slide column 2 is filled with air, and the injection housing 1 is filled with a mixture of solute and liquid. The liquid inlet hole is then closed by the push rod, and the mixed liquid in the injection housing 1 can be injected using the slide column.

[0051] In addition, after all the liquid is injected into the injection housing, the injection housing 1 can be shaken to accelerate the mixing of the mixed liquid.

[0052] In the disclosed embodiment, two injection assemblies are used to store a variety of tissue glue raw materials respectively. The sliding action of the push rod can be used to open the liquid inlet hole to mix the powder and liquid to generate a mixed liquid. The two mixed liquids are then regenerated into tissue glue, thereby facilitating the immediate production and use of tissue glue, achieving the advantages of sufficient mixing and reaction of liquids and rapid application.

[0053] During actual use, the slide column 2 of each injection component is filled with independent liquids, and the injection shell 1 of each injection component is provided with independent solutes; each injection component can open the liquid inlet hole through the push rod, so that the liquid and solute are mixed to form a mixed liquid, and then pass through the mixer to form tissue glue.

[0054] The tissue glue in this embodiment needs to form two spatially independent solutions, which are respectively formed by spatially independent powders and solvents. Since the powder is sealed in the injection shell 1 and the liquid is sealed in the slide column 2, it can preserve the spatially separated liquid and solute for a long time, and the tissue glue can be generated and applied simply and quickly when performing the operation.

[0055] In the tissue glue application device of this embodiment, the push rods 3 on the two injection assemblies are parallel to each other. Thus, during operation, the push rods can simultaneously open the two liquid inlet holes and push the slide column in a force direction to facilitate injection during the glue application process.

[0056] At this time, the same action can be used to open or close the liquid inlet holes in the two injection components, which facilitates the operation to the greatest extent.

[0057] Preferably, Figure 1 As shown, the tissue glue application device of this embodiment also includes: a connecting fixing frame 4 and a pull ring 5; the two injection components are fixed on the connecting fixing frame 4 in parallel with each other; the connecting fixing frame 4 can ensure that the two injection components are flush with each other, and the injection ports are both connected to the mixer 6 towards one end.

[0058] Pressing handles 40 are symmetrically provided on both sides of the connecting fixing frame 4 , and the push rods 3 on the two injection assemblies are both fixed on the pull ring 5 .

[0059] During the production process, since the two injection assemblies have the same structure, the injection assemblies can be produced in batches; the injection assemblies are then installed side by side on the connecting bracket 4, and then the pull ring is installed on the push rod to complete the production assembly process, which is simple and quick.

[0060] In this way, during the actual use of the mixed liquid, the pull ring 5 is first pushed to the left to open the liquid inlet hole, so that the solute and the liquid are mixed to form a mixed liquid; during the injection process, the fingers are pressed against the handle 40, and the thumb pushes the pull ring 5, so that the push rod drives the slide column 2 to be squeezed into the injection shell 1 to complete the injection action.

[0061] The tissue glue applying device of this embodiment is as follows Figure 1 This is a structural diagram of the tissue glue applying device according to an embodiment of the present disclosure. A limiting rod 7 is further provided on the connecting and fixing frame 4 . One end of the limiting rod 7 is fixed to the connecting and fixing frame 4 , and the other end abuts against the pull ring 5 .

[0062] Specifically, one end of the limiting rod 7 has a socket 70, which is fixed to the connecting fixing frame 4 through the socket 70; the other end of the limiting rod 7 rests on the pull ring 5, thereby avoiding pushing the sliding column 2 through the pull ring 5 during the process of generating the mixed liquid, thereby preventing the incompletely reacted mixed liquid from being injected in advance.

[0063] During the process of generating the mixed liquid, since only the push rod needs to be pulled to the right to open the liquid inlet and the slide hole, no additional operation of the slide column is required. Although the liquid inlet is open at this time, mixing can only be performed locally in the liquid inlet; the liquid cannot actively flow from the slide column 2 into the injection shell 1; the limit rod 7 can also ensure that the slide column does not squeeze the injection shell 1 to the left; at this time, the push rod 3 and the pull ring are kept stationary so that the liquid inlet remains open, and the two slide columns 2 are pulled to the right. Since the air pressure in the slide column 2 decreases, air is sucked into the slide column 2 from the push-pull end; at the same time, the volume in the injection shell 1 increases, and the liquid quickly flows into the injection shell 1 from the liquid inlet; at this time, the slide column 2 is full of air, and the injection shell 1 is a mixed liquid formed by solute and liquid. Then, the liquid inlet is closed by the push rod, and the mixed liquid in the injection shell 1 can be injected using the slide column.

[0064] During the injection process, it is only necessary to remove the limiting rod 7 so that the slide column can slide to the right relative to the injection housing 1 to perform the injection operation.

[0065] In this embodiment, Figure 2 and Figure 3 As shown, a sealing plug 20 is provided on the insertion end of the slide column 2, and the liquid inlet hole is opened on the sealing plug 20; the sealing plug 20 is generally a cylindrical rubber sealing plug, which is used to push the mixed liquid in the injection housing 1 during the injection process.

[0066] The plug 30 cooperates with the sealing plug 20 to open or close the liquid inlet hole.

[0067] Generally, the slide column 2 slides on the inner wall of the injection housing 1 through the sealing plug 20 .

[0068] During use, the sealing plug 20 not only seals the slide column 2 and the injection housing 1, but also effectively wraps and blocks the liquid inlet hole to prevent the liquid inlet hole from being opened prematurely, thereby further avoiding misoperation.

[0069] The entire working process of the tissue glue application device of the disclosed embodiment is as follows:

[0070] 1. In both injection assemblies of the present disclosure, the injection housing 1 is filled with solute, and the slide 2 is sealed with liquid. The liquid and solute in both injection assemblies are separated from each other. At this time, the plug 30 of the push rod 3 is located in the sealing plug 20 to seal the liquid inlet, thereby ensuring that the solute does not come into contact with the liquid prematurely.

[0071] 2. Push the push rod 3 to the left to remove the plug 30 from the sealing plug 20 to open the liquid inlet. Although the liquid inlet is open at this time, the pressure at both ends of the liquid inlet is balanced and liquid cannot enter the injection housing 1.

[0072] 3. Keep the push rod 3 and the pull ring relatively still with the slide column, and pull the two slide columns 2 to the right. As the air pressure in the slide column 2 decreases, air is sucked into the slide column 2 from the slide hole 21 through the air inlet groove 32. At the same time, the volume in the injection housing 1 increases, the air pressure decreases, and the liquid quickly flows into the injection housing 1 from the liquid inlet hole through the liquid inlet groove 31. At this time, the entire slide column 2 is filled with air.

[0073] 4. Pull the push rod to close the liquid inlet hole and shake it to accelerate the mixing of the mixed liquid in the injection housing 1;

[0074] 5. Turn the entire device upside down, and then gently push the slide column 2 to gently expel the excess air in the injection housing 1; remove the limit rod 7;

[0075] 6. Push the slide column 2, so that the mixed liquid in the injection shell enters the mixer 6 through the one-way valve, and after mixing, enters the nozzle 60 for spraying.

[0076] In addition, the tissue glue application device disclosed herein has low production costs, is small and exquisite, has a compact structural design, stable finished product quality, is easy and quick to use, and is suitable for the instant storage and configuration of various modified tissue glues and medical gels.

[0077] The serial numbers of the embodiments of the present disclosure are for description only and do not represent the advantages and disadvantages of the embodiments. Through the description of the above implementation methods, those skilled in the art can clearly understand that the above embodiment methods can be implemented by means of some deformations plus the necessary general technology superposition; of course, it can also be implemented by simplifying some important technical features. Based on this understanding, the technical solution of the present disclosure is essentially or the part that contributes to the prior art is: the overall structure and connection method, and the structure described in each embodiment of the present disclosure.

[0078] Finally, it should be noted that the above embodiments are only used to illustrate the technical solutions of the present disclosure, rather than to limit them. Although the present disclosure has been described in detail with reference to the aforementioned embodiments, those skilled in the art should understand that they can still modify the technical solutions described in the aforementioned embodiments, or replace some or all of the technical features therein with equivalents. However, these modifications or replacements do not cause the essence of the corresponding technical solutions to deviate from the scope of the technical solutions of the embodiments of the present disclosure.

Claims

1. A tissue glue application device, characterized in that: include: two injection assemblies and a mixer; The two injection assemblies are fixedly connected to each other and both have an injection port; The two injection ports are both connected to the mixer; Each of the injection assemblies comprises an injection housing, a slide column and a push rod; the injection housing is a cylindrical structure with an opening at one end and an injection port at the other end; the slide column is inserted into the injection housing through the opening and can slide along the injection housing; The slide column has a tubular cavity, and the two ends of the slide column are respectively an insertion end and a push-pull end; the insertion end is located in the injection housing, and the push rod is installed on the push-pull end; one end of the push rod is located in the cavity and can slide along the length direction of the cavity; The insertion end is provided with a liquid inlet hole; the push rod is provided with a plug for sealing the liquid inlet hole; the push rod slides relative to the cavity so that the plug opens the liquid inlet hole and the interior of the injection housing and the cavity are connected through the liquid inlet hole. The push-pull end is provided with a sliding hole, and the push rod slides in the cavity through the sliding hole; the push rod is provided with an air inlet groove, and when the plug opens the liquid inlet hole, the air inlet groove establishes a gas flow channel at the sliding hole; The push rod is provided with a liquid inlet groove; when the plug opens the liquid inlet hole, the liquid inlet groove establishes a liquid flow channel at the liquid inlet hole.

2. The tissue glue applying device according to claim 1, characterized in that: The push rods on the two injection assemblies are parallel to each other.

3. The tissue glue applying device according to claim 2, characterized in that: The device further comprises: a connecting fixing frame and a pull ring; the two injection assemblies are fixed on the connecting fixing frame in parallel with each other; Pressing handles are symmetrically provided on both sides of the connecting fixing frame, and the push rods on the two injection assemblies are fixed on the pull ring.

4. The tissue glue applying device according to claim 3, characterized in that: A limiting rod is also provided on the connecting and fixing frame; one end of the limiting rod is fixed on the connecting and fixing frame, and the other end abuts against the pull ring.

5. The tissue glue applying device according to claim 4, characterized in that: The slide column slides on the inner wall of the injection housing through a sealing plug.

6. The tissue glue applying device according to any one of claims 1 to 3, characterized in that: Each of the injection ports is provided with a switch valve, and each of the injection ports is connected to the mixer via the switch valve.

7. The tissue glue applying device according to any one of claims 1 to 3, characterized in that: The mixer is a Y-shaped mixer having an output port and two input ports that are interconnected; the mixer is connected to the two injection ports respectively through the two input ports; The output port is provided with a nozzle, which is an atomizer.

8. The tissue glue applying device according to claim 6, characterized in that: The switch valve is a one-way valve.

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