Heat-generating structure with solvent separation function and medical nebulizer

Abstract

The present application discloses a heating structure with a solvent separation function and a medical nebulizer. Among them, the heating structure with a solvent separation function includes: N + 1 liquid medicine infiltration units, which are used for infiltrating the target liquid medicine, and the liquid medicine infiltration units are in sheet form; N heating units, which are used for heating the target liquid medicine to separate the solvent of the target liquid medicine, and the shape of the heating unit is adapted to that of the liquid medicine infiltration unit, where N is a positive integer; the heating units and the liquid medicine infiltration units are arranged at intervals, and each heating unit is clamped between two liquid medicine infiltration units to form a liquid medicine absorber; a liquid medicine absorption unit, which is used for absorbing the target liquid medicine, and the liquid medicine absorption unit is arranged on the liquid medicine absorber; a first electrode, which penetrates the liquid medicine absorber, and the first electrode is used for connecting the N heating units in parallel. The heating structure with a solvent separation function removes the solvent that affects the taste, which can greatly improve the taste of the atomized liquid medicine and enable patients to have a better taste experience.

Description

Technical Field

[0001] This application belongs to the technical field of medical devices, and particularly relates to a heating structure with a solvent separation function and a medical nebulizer. Background Art

[0002] A nebulizer is an important component for atomizing solutions, and its performance has a significant impact on the precision of measurements and chemical interferences, etc. Therefore, it is required that the nebulizer has stable spraying, fine, uniform droplets, and high atomization efficiency. Nebulizers are widely used in various industries. In the medical field, nebulizers can deliver drugs to deeper lesion sites.

[0003] Current nebulizers are prone to damaging pharmacological components, and the taste of the atomized liquid medicine is not good. Summary of the Invention

[0004] The purpose of this application is to provide a heating structure with a solvent separation function and a medical nebulizer, which can improve the taste of the atomized liquid medicine without damaging the pharmacological components.

[0005] According to the first aspect of the embodiments of this application, a heating structure with a solvent separation function is provided. The heating structure with a solvent separation function may include:

[0006] N + 1 liquid medicine infiltration units, which are used for infiltrating the target liquid medicine, and the liquid medicine infiltration units are in sheet form;

[0007] N heating units, which are used for heating the target liquid medicine to separate the solvent of the target liquid medicine, and the shape of the heating unit is adapted to that of the liquid medicine infiltration unit, where N is a positive integer;

[0008] The heating units and the liquid medicine infiltration units are arranged at intervals, and each heating unit is clamped between two liquid medicine infiltration units to form a liquid medicine absorber;

[0009] A liquid medicine absorption unit, which is used for absorbing the target liquid medicine, and the liquid medicine absorption unit is arranged on the liquid medicine absorber;

[0010] A first electrode, which penetrates through the liquid medicine absorber, and the first electrode is used for connecting N heating units in parallel.

[0011] In some alternative embodiments of this application, the materials of the liquid medicine infiltration unit and the liquid medicine absorption unit are both porous ceramic materials.

[0012] In some alternative embodiments of this application, the liquid medicine infiltration unit and the adjacent heating unit are bonded by an adhesive.

[0013] In some alternative embodiments of this application, the heating unit includes:

[0014] Two protective films;

[0015] An electrothermal layer for heating the target liquid medicine. The electrothermal layer is sheet-shaped, and grooves are provided at both ends near the length direction of the electrothermal layer. The electrothermal layer is clamped between the two protective films;

[0016] A second electrode disposed inside the groove;

[0017] A fixing frame disposed on the periphery of the protective film. The fixing frame is used to fix the protective film and the electrothermal layer.

[0018] In some alternative embodiments of the present application, the material of the protective film is PET, PEN or PI.

[0019] In some alternative embodiments of the present application, the material of the electrothermal layer is graphene or carbon crystal.

[0020] In some alternative embodiments of the present application, the first electrode is a metal electrode, and the second electrode is a silver electrode or a copper electrode.

[0021] In some alternative embodiments of the present application, the material of the fixing frame is ceramic powder.

[0022] In some alternative embodiments of the present application, the upper surface of the liquid medicine absorption unit is wavy.

[0023] According to the second aspect of the embodiments of the present application, a medical nebulizer is provided. The medical nebulizer may include: a heating structure with a solvent separation function as described in any one of the embodiments of the first aspect.

[0024] The above technical solution of the present application has the following beneficial technical effects:

[0025] In the structure of the embodiment of the present application, the target liquid medicine is absorbed by the liquid medicine absorption unit, infiltrated by the liquid medicine infiltration unit, and then the absorbed target liquid medicine is heated by the heating unit. By precisely controlling the temperature gradient of the heating unit, the solvent of the target liquid medicine can be effectively separated without damaging the pharmacological components. Removing the solvent that affects the taste can greatly improve the taste of the atomized liquid medicine and give the patient a better taste experience. BRIEF DESCRIPTION OF THE DRAWINGS

[0026] Figure 1 is a schematic structural diagram of a heating structure with a solvent separation function in an exemplary embodiment of the present application;

[0027] Figure 2 is an exploded view of a heating structure with a solvent separation function in an exemplary embodiment of the present application;

[0028] Figure 3 It is an exploded view of a heating unit in an exemplary embodiment of the present application;

[0029] Figure 4 It is a schematic structural diagram of a heating unit in an exemplary embodiment of the present application;

[0030] Figure 5 It is a thermal simulation diagram of a heating structure with a solvent separation function in an exemplary embodiment of the present application. Detailed Description of the Invention

[0031] To make the objectives, technical solutions and advantages of the present application clearer, the present application will be further described in detail below in conjunction with the specific embodiments and with reference to the accompanying drawings. It should be understood that these descriptions are merely exemplary and are not intended to limit the scope of the present application. In addition, in the following description, descriptions of well-known structures and technologies are omitted to avoid unnecessarily obscuring the concepts of the present application.

[0032] The schematic diagram of the layer structure according to the embodiment of the present application is shown in the drawings. These figures are not drawn to scale, where for the purpose of clarity, some details are enlarged and some details may be omitted. The various regions, shapes of the layers shown in the figures, as well as their relative sizes and positional relationships are merely exemplary, and may actually deviate due to manufacturing tolerances or technical limitations, and those skilled in the art can design regions / layers with different shapes, sizes, and relative positions according to actual needs.

[0033] Obviously, the described embodiments are some but not all of the embodiments of the present application. All other embodiments obtained by those of ordinary skill in the art based on the embodiments in the present application without creative efforts shall fall within the scope of protection of the present application.

[0034] In the description of the present application, it should be noted that the terms "first", "second", and "third" are only used for descriptive purposes and cannot be construed as indicating or implying relative importance.

[0035] In addition, the technical features involved in different embodiments of the present application described below can be combined with each other as long as they do not conflict with each other.

[0036] The heating structure with a solvent separation function and a medical nebulizer provided by the embodiment of the present application will be described in detail below in conjunction with the accompanying drawings, through specific embodiments and their application scenarios.

[0037] As Figure 1 shown, in the first aspect of the embodiment of the present application, a heating structure with a solvent separation function is provided, and the heating structure with a solvent separation function may include:

[0038] N + 1 liquid medicine infiltration units 3016, where the liquid medicine infiltration unit 3016 is used for infiltrating the target liquid medicine, and the liquid medicine infiltration unit 3016 is in a sheet shape;

[0039] N heating units 3015, where the heating unit 3015 is used to heat the target liquid medicine to separate the solvent of the target liquid medicine, and the shape of the heating unit 3015 is adapted to that of the liquid medicine infiltration unit 3016, where N is a positive integer;

[0040] The heating unit 3015 and the liquid medicine infiltration unit 3016 are arranged at intervals, and each heating unit 3015 is clamped between two liquid medicine infiltration units 3016 to form a liquid medicine absorber;

[0041] A liquid medicine absorption unit 3017, which is used to absorb the target liquid medicine, and the liquid medicine absorption unit 3017 is arranged on the liquid medicine absorber;

[0042] A first electrode 3019, which penetrates the liquid medicine absorber, and the first electrode 3019 is used to connect N heating units 3015 in parallel.

[0043] The structure of the above embodiment absorbs the target liquid medicine through the liquid medicine absorption unit 3017, infiltrates the target liquid medicine with the liquid medicine infiltration unit 3016, and then uses the heating unit 3015 to heat the absorbed target liquid medicine. By precisely controlling the temperature gradient of the heating unit 3015, the solvent of the target liquid medicine can be effectively separated without damaging the pharmacological components. Removing the solvent that affects the taste can greatly improve the taste of the atomized liquid medicine and provide a better taste experience for patients. As Figure 2 shown, first, the liquid medicine infiltration unit 3016 and the liquid medicine absorption unit 3017 with equal thickness are fired with porous ceramic powder. The liquid medicine infiltration unit 3016 and the heating unit 3015 are arranged alternately and regularly, and the liquid medicine absorption unit 3017 is placed above the arrangement body of the two. Using the LTCC low-temperature co-firing technology, the functional components are first fired into sheet units and then co-fired into an integral whole. LTCC low-temperature co-firing technology: It is a technology that makes sheet units with precise thickness and density from low-temperature sintered ceramic powder, further processes different sheet units according to different functions, and then sinters all sheet units into a composite material.

[0044] In some alternative embodiments of the present application, the materials of the liquid medicine infiltration unit 3016 and the liquid medicine absorption unit 3017 are both porous ceramic materials. Specifically, porous sinterable ceramic powder can be selected.

[0045] In some alternative embodiments of the present application, the liquid medicine infiltration unit 3016 and the adjacent heating unit 3015 are bonded by an adhesive. Specifically, resin adhesives can be selected to improve the stability of the liquid medicine infiltration unit 3016 and the heating unit 3015.

[0046] As Figure 3 shown, in some alternative embodiments of the present application, the heating unit 3015 includes:

[0047] Two protective films 3013;

[0048] An electrothermal layer 3011 for heating the target liquid medicine. The electrothermal layer 3011 is in a sheet shape, and grooves are provided at both ends close to the length direction of the electrothermal layer 3011. The electrothermal layer 3011 is clamped between the two protective films 3013;

[0049] A second electrode 3012 disposed inside the groove;

[0050] A fixing frame 3014 disposed on the periphery of the protective film 3013. The fixing frame 3014 is used to fix the protective film 3013 and the electrothermal layer 3011.

[0051] When manufacturing the heating unit 3015, grooves are etched on the material of the electrothermal layer 3011 by laser, and silver paste electrodes are poured. After solidification, they form an integral body with the electrothermal layer 3011. Among them, laser etching: is to use a high-energy pulsed laser beam to etch grooves on the surface of parts, and is mostly applied to high-precision machining.

[0052] In the above embodiment, the first electrode 3019 can be installed by CNC machining to drill two through holes, penetrate all the second electrodes 3012, and install the first electrode 3019, one positive electrode and one negative electrode, so that all the internal heating units 3015 are connected in parallel and work with the same power. CNC machining: traditional CNC machine tool machining, and in this article, it is used to drill holes in composite materials and install electrodes. After combining the above units, they are placed in a mold, filled with ceramic powder or glass powder, and molded and sintered into a whole, as Figure 4 shown. Molding and sintering: filling the mold with a filling material, such as ceramic powder, and sintering it into a shape under a certain pressure.

[0053] In some alternative embodiments of the present application, the material of the protective film 3013 is PET, PEN or PI. Due to the good stability, insulation and corrosion resistance of this material, the heating unit and the liquid medicine infiltration unit 3016 are separated, without the risk of electric leakage and short circuit, and the resin used is harmless and corrosion-resistant, meeting the requirements of medical device EMC and safety regulations.

[0054] In some alternative embodiments of the present application, the material of the electrothermal layer 3011 is graphene or carbon crystal. Since this material generates heat in a planar manner, it ensures uniform heat distribution in the final composite material product and precisely controls the temperature gradient. The electrothermal layer 3011 is very thin and has insufficient thermal stability, and the resin protective film 3013 is required to provide support.

[0055] In some alternative embodiments of the present application, the first electrode 3019 is a metal electrode, and the second electrode 3012 is a silver electrode or a copper electrode.

[0056] In some alternative embodiments of the present application, the material of the fixing frame 3014 is ceramic powder.

[0057] In some alternative embodiments of the present application, the upper surface of the liquid medicine absorption unit 3017 is wavy. The wavy shape is to expand the contact area and increase the absorption efficiency.

[0058] As Figure 5 shown, it can be clearly seen from the cross-sectional and longitudinal-sectional screenshots of the thermal simulation that no matter from which point of the liquid medicine absorption unit 3017 the liquid medicine enters the heat-generating structure with a solvent separation function of the present application, it will experience the same temperature gradient to reach the bottom. The heat-generating structure with a solvent separation function of the present application realizes precise control of the heating gradient of the liquid medicine components. On this basis, only by adjusting the total voltage on the composite material metal electrode, the heating power of each heating unit 3015 can be controlled.

[0059] In an alternative embodiment of the present application, the target liquid medicine is as listed below. This target liquid medicine is a composition table of a herbal liquid for throat discomfort, in which the alcohol content is 16.23%. This herbal liquid is used as a representative of the liquid medicine with an alcohol solvent.

[0060]

[0061]

[0062] After retrieving the boiling points of all components, the lowest boiling point of alcohol is 78.3 °C, while the boiling points of the main pharmacological components in the herbal liquid are all above 200 °C. For other solvents, such as the boiling point of glycerol is 290 °C. For alcohol separation, the separation temperature is controlled between 80 °C and 100 °C to achieve the purpose of separating alcohol. According to experimental experience, 95 °C is preferred. For the atomization of pharmacological components, at least the boiling point of the other solvents after removing alcohol is required to atomize the liquid medicine, and too high a temperature will damage the pharmacological components. According to experimental experience, a temperature of 270 °C, which is 20 °C lower than the boiling point of glycerol, is preferred, which is sufficient to achieve a good atomization effect. The reason is that there is a large amount of air flow flowing through the application environment to generate negative pressure. Under this condition, glycerol can be fully atomized at 270 °C.

[0063] Taking this herbal liquid as an example, the heating structure with solvent separation function in the present application sets the corresponding power-on power according to the technical parameters of the alcohol separation temperature of 95°C and the atomization critical temperature of 270°C. The corresponding parameters are programmed into the MCU of the control system of the machine applied in the present application to achieve the function. For different liquid medicines or herbal liquids, the heating structure with solvent separation function of the present application can be used for power-on separation of the solvent components with low boiling points.

[0064] The heating structure with solvent separation function in the above embodiment can achieve precise control of the temperature gradient; the structural units are manufactured separately, and the overall composite material is co-fired at low temperature to maintain the optimal performance; it has an accurate solvent separation function and can separate the alcohol solvent without damaging the pharmacological components; the heating unit 3015 and the liquid medicine infiltration unit 3016 are separated, without the risk of electric leakage and short circuit, and the resin used is harmless and corrosion-resistant, meeting the requirements of medical device EMC and safety regulations.

[0065] According to the second aspect of the embodiments of the present application, a medical nebulizer is provided, which may include: the heating structure with solvent separation function according to any one of the embodiments of the first aspect.

[0066] The embodiments of the present application have been described above in conjunction with the accompanying drawings. However, the present application is not limited to the above specific embodiments. The above specific embodiments are merely illustrative and not restrictive. Under the inspiration of the present application, those of ordinary skill in the art can also make many forms without departing from the purpose of the present application and the scope protected by the claims, and all of them belong to the protection scope of the present application.

Claims

1. A heating structure with a solvent separation function, characterized in that, Including: N + 1 liquid medicine infiltration units (3016), the liquid medicine infiltration units (3016) are used for infiltrating the target liquid medicine, and the liquid medicine infiltration units (3016) are in sheet form; N heating units (3015), the heating units (3015) are used for heating the target liquid medicine to separate out the solvent of the target liquid medicine, and the shape of the heating units (3015) is adapted to that of the liquid medicine infiltration units (3016), where N is a positive integer; the heating units (3015) and the liquid medicine infiltration units (3016) are arranged at intervals, and each heating unit (3015) is clamped between two liquid medicine infiltration units (3016) to form a liquid medicine absorber; a liquid medicine absorption unit (3017) for absorbing the target liquid medicine, and the liquid medicine absorption unit (3017) is arranged on the liquid medicine absorber; a first electrode (3019) passing through the liquid medicine absorber, and the first electrode (3019) is used for connecting N heating units (3015) in parallel; The heating unit (3015) includes: two protective films (3013); a heating layer (3011) for heating the target liquid medicine, the heating layer (3011) is in sheet form, and grooves are provided at both ends close to the length direction of the heating layer (3011), and the heating layer (3011) is clamped between two protective films (3013); a second electrode (3012) arranged inside the grooves; a fixing frame (3014) arranged on the periphery of the protective film (3013), and the fixing frame (3014) is used for fixing the protective film (3013) and the heating layer (3011).

2. The heat-generating structure with a solvent separation function according to claim 1, characterized in that, The materials of the liquid medicine infiltration unit (3016) and the liquid medicine absorption unit (3017) are both porous ceramic materials.

3. The heat generating structure with a solvent separation function according to claim 1, characterized in that, The liquid medicine infiltration unit (3016) and the adjacent heating unit (3015) are bonded by an adhesive.

4. The heat generating structure with a solvent separation function according to claim 1, characterized in that, The material of the protective film (3013) is PET, PEN or PI.

5. The heat-generating structure with a solvent separation function according to claim 1, characterized in that, The material of the heating layer (3011) is graphene or carbon crystal.

6. The heat-generating structure with a solvent separation function according to claim 1, characterized in that, The first electrode (3019) is a metal electrode, and the second electrode (3012) is a silver electrode or a copper electrode.

7. The heat generating structure with a solvent separation function according to claim 1, characterized in that, The material of the fixing frame (3014) is ceramic powder.

8. The heat-generating structure with a solvent separation function according to claim 1, characterized in that, The upper surface of the liquid medicine absorption unit (3017) is wavy.

9. A medical nebulizer, characterized in that, Including: The heating structure with a solvent separation function according to any one of claims 1 - 8.

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