Methods, apparatus, and magnetic field therapy devices for customizing wearable magnetic field generating components

Abstract

The application provides a method, device and magnetic field treatment equipment for customizing a wearable magnetic field generating component. The method comprises: obtaining medical image data of an object containing a target region; determining the target region in the medical image data and determining a support position of an excitation coil on the object; determining model data of one or more excitation coils capable of focusing a magnetic field to the target region based on the target region and the support position; and customizing the wearable magnetic field generating component using the model data of the excitation coil.

Description

TECHNICAL FIELD

[0001] The present application relates to a magnetic field therapy device, and in particular to a method and device for customizing a wearable magnetic field generating component and a magnetic field therapy device. BACKGROUND

[0002] Based on the influence of magnetic field on human body or other animal body, a number of magnetic field therapy devices have been proposed, such as a transcranial magnetic stimulation instrument. It generates an alternating magnetic field by passing a short and strong pulse current in a coil placed above the head, and the alternating magnetic field can generate an induced current in the cranium through the high impedance medium (skin and skull), which will cause local depolarization of the cell membrane when the intensity of the induced current exceeds the excitation threshold of the nerve tissue, thereby stimulating the brain. In addition, some studies have found that magnetic field helps to inhibit the growth of tumor cells or destroy rapidly growing tumor cells, thus proposing a targeted therapy research based on magnetic field.

[0003] In the existing magnetic field therapy device, the magnetic field generating component can realize the focusing of the magnetic field, but its structure is fixed and cannot change the focusing for a specific area. In particular, when the magnetic field acts on the tumor, a long time is needed, so the magnetic field device needs to be worn. However, since the area where the tumor is located on the human body is not fixed relative to the supportable part of the human body surface, the use of the existing focused magnetic field in tumor focusing therapy is not convenient. SUMMARY

[0004] The technical problem to be solved by the present application is to provide a method for customizing a wearable magnetic field generating component and a magnetic field therapy device, which is convenient to wear and can realize a specific focused magnetic field for a target area.

[0005] To solve the above technical problem, the present application provides a method for customizing a wearable magnetic field generating component, comprising: obtaining medical image data of an object containing a target area; determining the target area in the medical image data and determining a support part of an excitation coil on the object; determining model data of one or more excitation coils capable of focusing a magnetic field to the target area based on the target area and the support part; and customizing the wearable magnetic field generating component using the model data of the excitation coil.

[0006] In an embodiment of the present application, the step of determining the support part of the excitation coil on the object in the medical image data comprises: determining the bone or skin surface of the object for supporting the excitation coil according to the target area in the medical image data.

[0007] In an embodiment of the present application, the step of determining the model data of one or more of the excitation coils capable of focusing the magnetic field to the target region based on the target region and the support position comprises: determining the model data of the excitation coils capable of focusing the magnetic field to the target region based on the spatial relationship between the target region and the support position, and taking the excitation coils adjustable at the support position as variables.

[0008] In an embodiment of the present application, the support position comprises a skull, and the step of manufacturing the wearable magnetic field generating component using the model data of the excitation coils comprises: generating model data of a helmet based on the model data of the excitation coils, and performing three-dimensional printing based on the model data of the excitation coils and the helmet.

[0009] In an embodiment of the present application, the support position comprises a torso, and the step of manufacturing the wearable magnetic field generating component using the model data of the excitation coils comprises: generating model data of a garment based on the model data of the excitation coils, and manufacturing the wearable magnetic field generating component based on the model data of the excitation coils and the covering structure.

[0010] In an embodiment of the present application, the target region comprises the lesion region.

[0011] In an embodiment of the present application, the method further comprises determining model data of wires connected to one or more of the excitation coils, and manufacturing the wearable magnetic field generating component using the model data of the excitation coils and the wires.

[0012] The present application further provides a device for customizing a wearable magnetic field generating component, comprising a memory for storing instructions executable by a processor, and the processor for executing the instructions to implement the following method: obtaining medical image data of an object containing a target region; determining the target region in the medical image data, and determining a support position of an excitation coil on the object; and determining model data of one or more of the excitation coils capable of focusing the magnetic field to the target region based on the target region and the support position.

[0013] The present application further provides a computer readable storage medium having stored thereon a computer program, which, when executed by a processor, implements the following method: obtaining medical image data of an object containing a target region; determining the target region in the medical image data, and determining a support position of an excitation coil on the object; and determining model data of one or more of the excitation coils capable of focusing the magnetic field to the target region based on the target region and the support position.

[0014] The application also provides a magnetic field treatment device, comprising a signal generator and a wearable magnetic field generating component for treatment. The signal generator is configured to generate an electrical signal corresponding to a magnetic signal for treatment. The wearable magnetic field generating component comprises a body customized for a treatment subject and one or more excitation coils arranged on the body and connected to the signal generator, the one or more excitation coils generating a magnetic field based on the electrical signal, wherein the position and direction of the excitation coils on the body are designed to focus the magnetic field to a target region of the subject.

[0015] In an embodiment of the application, the electrical signal is obtained from a drug sample and has a frequency ranging between 1 Hz and 22 kHz.

[0016] In an embodiment of the application, the body comprises a helmet or a piece of clothing.

[0017] Compared with the prior art, the wearable magnetic field generating component of the application is convenient for a patient to wear and can generate a specific focused magnetic field for a tumor in a specific region of the patient, so that the magnetic field energy can be better focused on the tumor while reducing the impact of the magnetic field energy on other regions of biological tissues. BRIEF DESCRIPTION OF DRAWINGS

[0018] The accompanying drawings are included to provide a further understanding of the application and are incorporated in and constitute a part of this application, illustrate embodiments of the application and together with the description serve to explain the principle of the application. In the drawings:

[0019] Figure 1 is a flow chart of a method for customizing a wearable magnetic field generating component according to an embodiment of the application.

[0020] Figures 2A-2D is a schematic diagram of a wearable magnetic field generating component according to an embodiment of the application.

[0021] Figure 3 is a schematic diagram of a wearable magnetic field generating component according to another embodiment of the application.

[0022] Figure 4 is a structural block diagram of a magnetic field treatment device according to an embodiment of the application.

[0023] Figure 5 is a hardware structure diagram of an apparatus for customizing a wearable magnetic field generating component according to an embodiment of the application. DETAILED DESCRIPTION

[0024] In order to illustrate the technical solutions of the embodiments of the present application more clearly, the drawings needed in the embodiment description will be briefly introduced. Obviously, the drawings in the following description only show some examples or embodiments of the present application, and those skilled in the art can further apply the present application to other similar situations without any creative effort, based on the drawings. The same reference signs in the drawings represent the same structure or operation, unless otherwise clear from the context or otherwise indicated.

[0025] As shown in the present application and claims, unless the context clearly indicates otherwise, the words "one", "an", "a", and / or "the" do not mean "only one", but can include a plurality or "one or more" unless the context clearly indicates otherwise. Generally, the terms "comprising" and "including" only indicate the inclusion of the steps and elements explicitly identified in the context, and these steps and elements do not constitute an exclusive list, and the method or device can also include other steps or elements.

[0026] Unless specifically stated otherwise, the relative arrangement of components and steps, numerical expressions, and numerical values set forth in the various embodiments described herein are not meant to limit the scope of the present application. It is also to be understood that the various parts shown in the drawings are not necessarily drawn to scale and that, for purposes of convenience and clarity, not all components and steps can be shown in the drawings. Techniques, methods, and devices known to those of ordinary skill can not be discussed in detail, but should be considered as if discussed in detail herein, where appropriate. In all examples shown and discussed herein, any specific values should be interpreted as merely illustrative and not as a limitation on the scope of the exemplary embodiments. Thus, other example embodiments of the present application can have different values. It is to be noted that like reference numerals and letters refer to like items in the drawings and, as such, once an item is defined in one drawing, it need not be discussed further in subsequent drawings.

[0027] In the description of the present application, it should be understood that the orientation words such as "front, back, up, down, left, right", "horizontal, vertical, perpendicular, horizontal", and "top, bottom" and the like indicate the orientation or positional relationship based on the orientation or positional relationship shown in the drawings, and are only for the convenience of describing the present application and simplifying the description, and do not indicate or imply that the indicated device or element must have a particular orientation or be constructed and operated in a particular orientation, unless otherwise stated, and therefore cannot be understood as a limitation on the scope of protection of the present application; the orientation words "inner, outer" refer to the inner and outer relative to the contour of the components themselves.

[0028] For purposes of the description hereinafter, the terms "upper", "lower", "right", "left", "vertical", "horizontal", "top", "bottom", "lateral", "medial", "superior", "inferior", "proximal", "distal" and derivatives thereof (e.g., "horizontally", "downwardly", "upwardly", etc.) relate to the apparatus as it is shown in the drawings, unless otherwise specifically noted. It is to be understood that the spatially relative terms are intended to encompass different orientations of the device in use or operation in addition to the orientation depicted in the drawings. For example, if the device described herein is inverted consistent with the use or operation of the device, then a component or feature that is described as "above" or "up" other elements is to be oriented "below" or "down" the other elements with the inverted orientation. Thus, the exemplary term "above" can encompass both an orientation of above and below. The apparatus can be otherwise oriented (rotated 90 degrees or at other orientations) and the spatially relative descriptors used herein interpreted accordingly. It is to be understood that the spatially relative terms are intended to encompass different orientations of the device in use or operation in addition to the orientation depicted in the drawings. For example, if the device described herein is inverted consistent with the use or operation of the device, then a component or feature that is described as "above" or "up" other elements is to be oriented "below" or "down" the other elements with the inverted orientation. Thus, the exemplary term "above" can encompass both an orientation of above and below. The apparatus can be otherwise oriented (rotated 90 degrees or at other orientations) and the spatially relative descriptors used herein interpreted accordingly.

[0029] In addition, it should be noted that the use of "first", "second", "third", etc. words to describe various components is only intended to differentiate one component from another, and is not intended to limit the scope of the present application. Unless otherwise stated, the above words are not intended to have special meanings. In addition, although the terms used in the present application are selected from well-known and commonly-used terms, some terms mentioned in the present application may be selected by the applicant according to his or her judgment, and the detailed meanings of the terms are described in the relevant parts of the description. In addition, the present application is required to be understood not only by the actual terms used, but also by the meaning implied by each term.

[0030] It will be understood that when a component is referred to as being "on" another component, "connected to" another component, "coupled to" another component, or "in contact with" another component, it can be directly on, connected to, coupled to, or in contact with the other component, or one or more intervening components can also be present. In contrast, when a component is referred to as being "directly on", "directly connected to", "directly coupled to", or "directly in contact with" another component, there are no intervening components present. Similarly, when a first component is referred to as being "electrically in contact with" or "electrically coupled to" a second component, there is an electrical path between the first component and the second component that allows electrical current to flow. The electrical path can include capacitors, coupled inductors, and / or other components that allow electrical current to flow, even without direct contact between conductive components.

[0031] Embodiments of the present application describe a method of customizing a wearable magnetic field generating component for a patient, and to generate a specific focused magnetic field for a tumor in a specific area of the patient, so that the magnetic field energy can be better focused on the tumor, while reducing the impact of the magnetic field energy on other areas of biological tissue. Embodiments of the present application describe a magnetic field treatment device having the aforementioned customized wearable magnetic field generating component.

[0032] Figure 1 is a flow chart of a method of customizing a wearable magnetic field generating component according to an embodiment of the present application. Referring to Figure 1 the embodiment customizes a wearable magnetic field generating component, which includes the following steps.

[0033] At step 101, medical image data of an object containing a target region is acquired.

[0034] Here, the target region is typically a lesion region, such as a tumor region. The target region can also be a normal region of the object. Here, the object can be a human body or other animal body, especially a mammal.

[0035] Here, the medical image data is, for example, CT image data, PET-CT image data, MR (magnetic resonance) image data, and the like, which can reflect the target region of the object. It can be understood that one or more types of image data can be acquired, such as CT image data and MR image data can be acquired at the same time. The medical image data can be two-dimensional image data or three-dimensional image data.

[0036] In embodiments of the present application, the aforementioned various medical image data can be acquired by various medical image devices and transmitted to a workstation, such as a personal computer, coupled to the medical image devices. In some embodiments, the acquisition step includes taking medical image data in real time. In some embodiments, the medical image data is pre-taken and saved in the workstation, a local server or a remote server, and the acquisition step includes accessing these devices to load the medical image data.

[0037] At step 102, the target region is determined in the medical image data, and a support site of the excitation coil on the object is determined.

[0038] Here, the spatial position of the target region in the medical image data is determined. For example, a coordinate system is established in the medical image data, and the coordinate value of the target region in the coordinate system is determined.

[0039] In one embodiment, the target region specified by a user in the medical image data through a mouse or a handwriting board and the like input tool in a computer can be received, and the spatial position of the target region is determined accordingly.

[0040] In another embodiment, a trained recognition model is used in a computer to recognize the target region in the medical image data, and the spatial position of the target region is further determined. For example, a neural network model can be used to recognize a tumor region for a tumor. In some embodiments, the recognized target region can be confirmed by a user.

[0041] Here, the support site is a site on the subject that can support the excitation coil. For the torso part of the subject, the typical support site is the skin surface. Preferably, the skin surface with the bone underneath, for example within a few millimeters, is chosen as the support site to reduce the influence of skin deformation on the support effect. For the head of the subject, the typical support site is the skull. Thus, in one embodiment, according to the target region determined previously, the bone or the skin surface of the subject for supporting the excitation coil is determined in the image data. Taking a brain tumor as an example, the target region is the brain tumor, and the support site is the skull of the human.

[0042] In step 103, based on the target region and the support site, the model data of one or more excitation coils capable of focusing the magnetic field to the target region is determined.

[0043] In this step, the number of excitation coils can be determined according to parameters such as the shape, position, magnetic field strength requirement of the target region. In this step, based on the spatial relationship between the target region and the support site, the model data of the excitation coil capable of focusing the magnetic field to the target region is determined with the excitation coil adjustable at the support site as the variable. The model data can include the shape, position and direction of the excitation coil in the body.

[0044] In step 104, the wearable magnetic field generating component is customized using the model data of the excitation coil.

[0045] In this step, after the model data of the excitation coil is determined, the body of the wearable magnetic field generating component can be constructed according to the support needs and the wearing needs of the subject. Further, based on the model data of the excitation coil and the body, the wearable magnetic field generating component is customized.

[0046] For a helmet-type wearable magnetic field generating component, the model data of the helmet can be generated based on the model data of the excitation coil, and the helmet is three-dimensionally printed based on the model data of the excitation coil and the helmet.

[0047] For a clothing-type wearable magnetic field generating component, the model data of the clothing can be generated based on the model data of the excitation coil, and the wearable magnetic field generating component is made based on the model data of the excitation coil and the covering structure.

[0048] In some embodiments, the model data of the wire connecting the excitation coil is also determined. In step 104, the wearable magnetic field generating component is made using the model data of the excitation coil and the wire.

[0049] In one embodiment, the various steps of generating the model data of the wearable magnetic field generating component can be completed in a computer, and the model data of the wearable magnetic field generating component is obtained for subsequent manufacturing. These steps can be instantiated as a computer program and saved in a computer readable storage medium.

[0050] Flowcharts are used in this application to illustrate the operations performed by systems according to embodiments of the application. It should be understood that the operations in the figures need not necessarily be performed in the order shown. Rather, various steps can be handled in different order or simultaneously. Also, or alternatively, other operations can be added or removed from these processes.

[0051] Figures 2A-2D is a schematic view of a wearable magnetic field generating component according to an embodiment of the application. Referring to Figures 2A-2D shown, a helmet-type wearable magnetic field generating component 20 includes a body 21, a plurality of excitation coils 22a-22c, and a cable 23. The body 21 is custom-made for a subject of treatment, such as a patient, so that its size and shape conform to the patient's skull, and thus can be worn conveniently and comfortably. The number of excitation coils is merely exemplary, and can be one, two, or more than three. The excitation coils are disposed on the body 21. For example, the excitation coil 22a is disposed at a receiving site 21a of the body 21, the excitation coil 22b is disposed at a receiving site 21b of the body 21, and the excitation coil 22c is disposed at another receiving site (not shown) of the body 21. The excitation coils are shown in the figure, but it is understood that each excitation coil is built in each receiving site. Each excitation coil 22a-22c is connected to a signal generator (not shown) through the cable 23 to receive an electric signal. Each excitation coil generates a magnetic field based on the electric signal. Here, the position and orientation of each excitation coil 22a-22c on the body 21 are designed to focus the magnetic field to a target region 10 of the subject.

[0052] The wearable magnetic field generating component of the embodiment can be custom-made according to the method shown, but is not limited thereto. Figure 1

[0053] In this embodiment, the signal generator is disposed outside the wearable magnetic field generating component to simplify its structure and reduce its weight. In another embodiment, the signal generator is disposed inside the wearable magnetic field generating component, and an external power source is connected through a power cable. In yet another embodiment, a battery can be installed in the wearable magnetic field generating component to power the signal generator.

[0054] Figure 3 is a schematic view of a wearable magnetic field generating component according to another embodiment of the application. Referring to Figure 3 ​As shown, a garment-type wearable magnetic field generating component 30 includes a body 31, a plurality of excitation coils 32a-32c. The body 31 is customized for a subject of treatment, such as a patient, to have a size and shape that conforms to the size and shape of the patient's torso, so that it can be worn conveniently and comfortably. The number of excitation coils is merely an example, and can be one, two, or more than three. The excitation coils are disposed on the body 31. For example, the excitation coils 32a-32c are disposed in respective receiving sites on the body 31. The excitation coils are shown in the figure, but it is understood that each excitation coil is built into the respective receiving site. Each excitation coil 32a-32c is connected by a cable (not shown) to a signal generator (not shown) to receive an electrical signal. Each excitation coil generates a magnetic field based on the electrical signal. Here, the position and orientation of each excitation coil 32a-32c on the body 31 are designed to focus the magnetic field to the target region 10' of the subject.

[0055] The wearable magnetic field generating component of the present embodiment can be customized according to the method shown, but is not limited thereto. Figure 1

[0056] In the present embodiment, the signal generator is disposed outside the wearable magnetic field generating component to simplify its structure and reduce its weight. In another embodiment, the signal generator is disposed inside the wearable magnetic field generating component and is connected to an external power source by a power cable. In yet another embodiment, a battery can be installed in the wearable magnetic field generating component to power the signal generator.

[0057] Figure 4 is a block diagram of the structure of a magnetic field therapy device according to an embodiment of the present invention. Referring to Figure 4 As shown, the magnetic field therapy device 400 of the present embodiment includes a signal generator 410, a power source 420, and the aforementioned wearable magnetic field generating component. The wearable magnetic field generating component has one or more excitation coils 431. The signal generator 410 is configured to generate an electrical signal corresponding to a magnetic signal used for therapy. The signal generator 410 includes a signal storage 411, a signal transmitter 412, and a signal amplifier 413. The signal storage 411 stores an electrical signal waveform, which can be extracted and loaded into the signal transmitter 412 to generate an electrical signal with a certain amplitude and delivered to the signal amplifier 413. After passing through the signal amplifier 413, the electrical signal amplitude reaches the required requirement to excite a magnetic field of a certain intensity, and is delivered to the excitation coils 431 in the wearable magnetic field generating component.

[0058] ​In some embodiments, the electrical signal waveform in signal memory 411 is acquired from a pharmaceutical sample. The principle behind this approach is that the mechanism of action of some chemical, biochemical, or biological pharmaceutical treatments is a weak electromagnetic signal that is produced. By producing a magnetic field that mimics the molecular signal of a particular chemical, biochemical, or biological pharmaceutical, an effect similar to the chemical, biochemical, or biological treatment can be provided. In some embodiments, noise at an amplitude sufficient to produce stochastic resonance can be injected into the pharmaceutical sample, the injection of noise repeated at each of a plurality of noise levels within a selected range of noise levels, and detected using a superconducting quantum interference device (SQUID) until the source radiation of the pharmaceutical sample is distinguishable over the injected noise.

[0059] In some embodiments, the aforementioned electrical signal has a frequency in the range of 1 Hz and 22 kHz.

[0060] The custom wearable magnetic field generation methods described above can be instantiated as computer program code and maintained and executed, for example, in a device as shown in Figure 5 to implement the custom wearable magnetic field generation apparatus of the present application. Referring to Figure 5 As shown, the apparatus 100 includes an internal communication bus 101, a processor 102, a hard disk 103, a read only memory (ROM) 104, a random access memory (RAM) 106, and a communication port 107. The internal communication bus 101 can enable data communication among the components of the apparatus. The processor 102 can execute programs to control the workflow of the apparatus. In some embodiments, the processor 102 can be composed of one or more processors. When implemented as a personal computer, the apparatus 100 can include the hard disk 103. The communication port 107 can enable data communication of the apparatus 100 with the outside. In some embodiments, the apparatus 100 can send and receive information and data from a network through the communication port 107. The apparatus 100 can also include different forms of program storage units and data storage units, such as the read only memory 104 and the random access memory 106, capable of storing various data files used by the computer processing and / or communication, and possible program instructions executed by the processor 102.

[0061] Having described the basic concepts, it is obvious to those skilled in the art that the above-described disclosure of the invention is merely exemplary and does not limit the present application. Although not explicitly described herein, those skilled in the art can make various modifications, improvements, and corrections to the present application. Such modifications, improvements, and corrections are suggested in the present application, so such modifications, improvements, and corrections still belong to the spirit and scope of the exemplary embodiments of the present application.

[0062] Also, certain terminology can also be used in the description for the sake of brevity. For example, the terms "some" and "one" can be read to indicate "one or more" or "one or more than one." Also, the terms "first," "second," or the like can be understood to mean only "first" and "second," or they can be understood to mean "first," "second," or "third," or the like, depending on the context. The use of these terms in the description is only to facilitate representation of one or more embodiments and is not intended to limit one or more embodiments, or a preferred or exemplary embodiment, to a given combination or sub-combination of features.

[0063] Aspects of the present application can be implemented in hardware, firmware, software, or any combination thereof. The various elements of the present application can be implemented as any one or more of a computer program product, an integrated circuit, a combinational logic circuit, a field programmable gate array (FPGA), a system on a chip (SoC), or other programmable logic device. Various aspects of the present application can be implemented in any of the following technologies: a computer implemented system, a software application, a computer using process, a computer using hardware, or any combination thereof. The computer program product can be tangibly embodied in an information carrier in a machine readable medium for execution by a programmable processor; and the machine readable medium can include non-transitory, computer readable storage media tangibly embodying computer readable instructions or computer program code. The computer readable storage media can include, without limitation, nonvolatile memory, such as flash memory, disk drive memory, data storage tapes, and the like. Additionally or alternatively, the computer readable storage media can include volatile memory, such as static random access memory (SRAM) and the like. The computer readable storage media can also include media such as quantum memory, optical quantum memory, and the like. The computer readable storage media can be tangible and non-transitory. The computer readable storage media can also be physically distributed over networks or cloud, either publicly or privately. The computer program product can also include computer program code that can be downloaded into the computer or device over a network for execution. Accordingly, the present application is not limited to a purely software or hardware implementation, but rather the present application can be implemented in any combination of software and hardware.

[0064] The computer readable medium can include a propagated data signal with computer program code embodied therein. The computer readable medium can also include computer readable storage media. The computer readable storage media can be any available media that can be accessed by a general purpose or special purpose computer. By way of example, and not limitation, such computer readable storage media can comprise RAM, ROM, EEPROM, CD-ROM or other optical disk storage, magnetic disk storage or other magnetic storage devices, or any other storage medium(s) that can be used to carry or store desired computer program code in the form of instructions or data structures and that can be accessed by a general-purpose or special-purpose computer, or a general-purpose or special-purpose processor. Also, any connection is properly termed a computer readable medium. For example, if the computer readable medium is the Internet, then any suitable connection is properly termed a computer readable medium. Combinations of the above should also be included within the scope of the computer readable media.

[0065] In this document, relational terms such as first and second, and the like can be used solely to distinguish one entity or action from another entity or action, without necessarily implying any actual such relationship or order between such entities or actions. Also, the prefix "one" or "another" can be used in this document to describe various embodiments. Such prefix is only used in the concise description thereof, but not in the claims. In the appended claims, the terms comprising and including and their derivatives can be used and are intended to be equivalent to the term including. Also, the singular forms of words such as "a", "an" and "the" are intended to mean "one or more" or "at least one", unless the context clearly indicates otherwise. Finally, terms such as "program" or "software" can be used to generally refer to any type of computer program code, including code that is executable by a processor, as well as code that is not directly executable, such as code that is compiled to create executable code or code that is interpreted at runtime. For example, in some embodiments, a program can be a high-level code that is compiled to create an executable code or an executable code that is interpreted at runtime. Also, terms such as "processor" can be used to generally refer to any processing device, including one or more central processing units (CPUs) or other processors.

[0066] Some embodiments use numerical descriptors of ingredients, amounts of ingredients, and properties. It should be understood that such numerical descriptors used in the description of embodiments are, in some examples, modified by the terms "about," "approximately," or "generally." Unless otherwise stated, "about," "approximately," or "generally" indicates that a deviation of ±20% is allowed on the stated number. Accordingly, numerical parameters in the specification and claims are approximations, and should be considered in the context of the overall description of the embodiments. In some embodiments, numerical parameters are approximations and should be considered in the context of the overall description of the embodiments. In some embodiments, numerical parameters should be considered in the context of the specification and the claims, and are approximations that vary from the numerical parameters in some examples. Although the numerical ranges and parameters setting forth the broadest scope of the embodiments herein are approximations, the numerical values set forth in the specific examples are reported as precisely as practicable. The numerical values set forth in the specific examples are provided to be as precise as reasonably possible. However, some variations may occur depending on the implementation desired.

[0067] Although the present application has been described with reference to the current embodiments, persons having ordinary skill in the art will recognize that changes may be made in form and detail without departing from the spirit and the scope of the application. Therefore, the disclosed embodiments should be considered in a descriptive sense only and not for purposes of limiting the applicability of the application, as broadly construed.

Claims

1. A magnetic field therapy device, comprising: A signal generator configured to generate an electrical signal corresponding to a magnetic signal used for treatment; A wearable magnetic field generating component for treatment includes a body customized for the treatment subject and one or more excitation coils. The body is configured to meet the support requirements of the excitation coils and the wearability requirements of the treatment subject. The one or more excitation coils are disposed on the body and connected to a signal generator. The one or more excitation coils generate a magnetic field based on an electrical signal. The position and orientation of the excitation coils on the body are designed to focus the magnetic field onto a target area of ​​the subject. The electrical signal is acquired from the drug sample and has a frequency in the range of 1 Hz to 22 kHz. Noise at an amplitude sufficient to produce random resonance is injected into the drug sample. The noise is injected repeatedly at each of a plurality of noise levels within a selected noise level range and detected using a superconducting quantum interference device until the source radiation of the drug sample is distinguishable from the injected noise.

2. The magnetic field therapy device as described in claim 1, characterized in that, The body may include a helmet or clothing.

3. The magnetic field therapy device as described in claim 1, characterized in that, The method for customizing the wearable magnetic field generating component includes: Acquire medical image data of objects containing the target region; The target region is determined from the medical imaging data, and the support location of the excitation coil on the object is determined; Based on the target area and supporting components, model data for one or more excitation coils capable of focusing the magnetic field onto the target area are determined; and The body of the wearable magnetic field generating component is constructed according to the support requirements of the excitation coil and the wearing requirements of the object, and the wearable magnetic field generating component is customized using the model data of the excitation coil and the body.

4. The magnetic field therapy device as described in claim 3, characterized in that, The step of determining the support location of the excitation coil on the object in the medical imaging data includes: determining, based on the target region, the bone or skin surface of the object that supports the excitation coil in the medical imaging data.

5. The magnetic field therapy device as described in claim 3, characterized in that, The step of determining model data for one or more excitation coils capable of focusing a magnetic field onto the target area, based on the target area and supporting components, includes: Based on the spatial relationship between the target area and the supporting parts, and taking the excitation coil that can be adjusted at the supporting parts as a variable, model data of the excitation coil that can focus the magnetic field to the target area is determined.

6. The magnetic field therapy device as described in claim 4, characterized in that, The supporting part includes the skull, and the step of making the wearable magnetic field generating component using the model data of the excitation coil includes: generating model data of the helmet based on the model data of the excitation coil, and performing 3D printing based on the model data of the excitation coil and the helmet.

7. The magnetic field therapy device as described in claim 4, characterized in that, The support portion includes the torso, and the step of creating the wearable magnetic field generating component using the model data of the excitation coil includes: generating model data of clothing based on the model data of the excitation coil, and creating the wearable magnetic field generating component based on the model data of the excitation coil and the clothing.

8. The magnetic field therapy device as described in claim 4, characterized in that, The target area includes the lesion area.

9. The magnetic field therapy device as described in claim 4, characterized in that, It also includes model data for determining the wires connecting one or more of the excitation coils, and The wearable magnetic field generating component is fabricated using model data of the excitation coil and the conductor.

10. A device for a custom-designed wearable magnetic field generating component, comprising: Memory is used to store instructions that can be executed by the processor; as well as A processor is configured to execute the instructions to implement the following method: Acquire medical image data of objects containing the target region; The target region is determined from the medical imaging data, and the support location of the excitation coil on the object is determined; as well as Based on the target area and supporting components, model data for one or more excitation coils capable of focusing the magnetic field onto the target area are determined; as well as The body of the wearable magnetic field generating component is constructed based on the support requirements of the excitation coil and the wearability requirements of the object. The wearable magnetic field generating component is customized using the model data of the excitation coil and the body. The magnetic field therapy device includes a signal generator and a wearable magnetic field generating component for treatment. The signal generator is configured to generate an electrical signal corresponding to a magnetic signal for treatment. The electrical signal is acquired from a drug sample and has a frequency in the range of 1 Hz to 22 kHz. Noise with an amplitude sufficient to produce random resonance is injected into the drug sample. The noise is repeatedly injected at each of a plurality of noise levels within a selected noise level range and detected using a superconducting quantum interference device until the source radiation of the drug sample is distinguishable from the injected noise.

11. A computer-readable storage medium having a computer program stored thereon, characterized in that, When the computer program is executed by the processor, it implements the following method: Acquire medical image data of objects containing the target region; The target region is determined from the medical imaging data, and the support location of the excitation coil on the object is determined; as well as Based on the target area and supporting components, model data for one or more excitation coils capable of focusing the magnetic field onto the target area are determined. The wearable magnetic field generating component is constructed based on the support requirements of the excitation coil and the wearability requirements of the object. The wearable magnetic field generating component is customized using model data of the excitation coil and the body. The magnetic field therapy device includes a signal generator and the wearable magnetic field generating component for treatment. The signal generator is configured to generate an electrical signal corresponding to the magnetic signal for treatment. The electrical signal is acquired from a drug sample and has a frequency in the range of 1 Hz to 22 kHz. Noise with a noise amplitude sufficient to produce random resonance is injected into the drug sample. The noise is repeatedly injected at each of multiple noise levels within a selected noise level range and detected using a superconducting quantum interference device until the source radiation of the drug sample is distinguishable from the injected noise.

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