Biological tissue dehydration apparatus
By combining a multi-channel switching valve system and a rotary drive assembly, the problems of processing efficiency and liquid mixing in existing biological tissue dehydration equipment are solved, realizing a fast and efficient dehydration and wax impregnation process and improving the equipment's processing capacity.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- Filing Date
- 2022-02-10
- Publication Date
- 2026-04-07
AI Technical Summary
Existing biological tissue dehydration equipment has shortcomings in processing efficiency and liquid mixing, which affect the processing effect of tissue specimens.
A multi-channel switching valve system, combined with a rotary drive assembly and an encoder, enables rapid switching between the dehydration solvent chamber and the paraffin chamber and the working cylinder. The solvent and paraffin are transported through a liquid extraction assembly, ensuring rapid process switching and accurate liquid delivery.
It enables rapid and efficient switching between biological tissue dehydration and paraffin infiltration processes, improving equipment processing efficiency, avoiding liquid mixing, and ensuring the processing effect of tissue specimens.
Smart Images

Figure CN114397164B_ABST
Abstract
Description
Technical Field
[0001] This invention relates to the field of tissue dehydration technology, and in particular to a biological tissue dehydration device. Background Technology
[0002] Currently, biological tissue dehydration equipment is used as the primary instrument in medical and laboratory departments for the analysis of biological tissue pathological sections. Biological tissue dehydration equipment requires heating in a closed environment during the dehydration and paraffin infiltration of biological tissues. For example, the dehydration process involves heating dehydration reagents in a closed dehydration tank to dehydrate the biological tissue.
[0003] Existing tissue dehydrators are classified into two types based on their operating methods. One type arranges several reagent cylinders containing different solutions, such as alcohol, xylene, and liquid paraffin, in a circular or linear pattern, and then uses a robotic arm to sequentially immerse tissue specimens into these cylinders for processing. The other type uses a pump to sequentially draw liquids from each reagent cylinder into a fixed reaction cylinder containing the tissue specimen. Dehydrators using the first type are gradually being phased out due to their small capacity and low efficiency. Dehydrators using the second type have a large capacity and higher efficiency; however, this type requires multiple valves to coordinate and prevent mixing of the various liquids during sequential extraction, which could affect the processing results of the tissue specimens. Summary of the Invention
[0004] The purpose of this invention is to provide a biological tissue dehydration device to solve one or more technical problems existing in the prior art, and at least provide a beneficial option or create conditions.
[0005] This invention provides a biological tissue dehydration device, including a device body and a working cylinder, multiple dehydration solvent chambers, a paraffin chamber and a multi-channel switching valve assembled in the device body;
[0006] The multi-channel switching valve includes a rotary drive assembly and a switching valve body. The switching valve body is provided with a first output channel and multiple sets of first input channels. The dehydration solvent chamber and the paraffin chamber are respectively connected to the first input channels. The first output channel is connected to the liquid inlet end of the working cylinder. A liquid extraction assembly is provided between the first output channel and the liquid inlet end of the working cylinder.
[0007] When the switching valve body and the rotary drive assembly are in transmission cooperation, a first output channel can be connected to a first input channel, so that the working cylinder can be connected to the corresponding dehydration solvent chamber or paraffin chamber. The pumping and discharging assembly can draw the contents of the dehydration solvent chamber or paraffin chamber into the working cylinder, or discharge the contents of the working cylinder into the dehydration solvent chamber or paraffin chamber.
[0008] Furthermore, the multi-channel switching valve also includes an encoder and a sensor detection unit;
[0009] The encoder disk is fixedly connected to the rotating end of the rotary drive assembly. The encoder disk is engraved with absolute codes for representing absolute positions and relative codes for representing relative positions. The number of relative codes is an integer multiple of the number of the first input channels. The number of absolute codes is the same as the number of relative codes, and the absolute codes and relative codes correspond one-to-one.
[0010] The sensing unit and the encoder disk are arranged to be relatively movable, and the sensing unit detects the absolute and relative codes passing through its detection area;
[0011] When the switching valve body and the rotary drive assembly are in transmission cooperation, the first output channel indicated by the absolute position and the first input channel can be connected accordingly.
[0012] Furthermore, the number of absolute codes is twice the number of the first input channels, and the number of absolute code detection points in the sensing detection unit satisfies the following relationship with the number of the first input channels:
[0013] 2 n ≥2P;
[0014] Where n represents the number of absolute coding detection sites, and P represents the number of first input channels.
[0015] Furthermore, the biological tissue dehydration device also includes a controller, which is connected to the rotary drive assembly and the sensing and detection unit respectively. The encoder disk is also engraved with zero-position detection points to indicate the zero position. The controller verifies whether the detected relative position reaches the cumulative threshold and whether the detected zero position matches each other based on the relative position obtained by detecting the relative encoding and the position of the zero-position detection point.
[0016] Furthermore, the switching valve body includes a valve body housing and a moving valve plate and a fixed valve plate assembled inside the valve body housing. The moving valve plate and the fixed valve plate are stacked and configured, and the rotary drive assembly is drivenly connected to the moving valve plate.
[0017] The moving valve plate has a first output common hole at its center and a first input common hole around its periphery. The fixed valve plate has several first input holes, which are spaced apart from each other with the first output common hole as the center. The first output common hole is connected to the first output channel, and the first input common hole is connected to the first output common hole. Each first input hole is connected to each first input channel. When the rotary drive assembly drives the moving valve plate to rotate, the first output common hole is connected to one of the first input holes through the first input common hole, so that the first output channel is connected to one of the first input channels.
[0018] Furthermore, the switching valve body is also provided with a second output channel and several sets of second input channels. The first input channel and the second input channel correspond one-to-one. When the switching valve body is in transmission cooperation with the rotary drive assembly, the first output channel indicated by the absolute position and the relative position can be connected to the first input channel and the second output channel can be connected to the second input channel.
[0019] Furthermore, the working cylinder is equipped with a stirring component and a drive assembly;
[0020] The agitator is located at the bottom of the inner cavity of the working cylinder. The top of the agitator has an upwardly protruding top pressure part. The rotating end of the drive component enters the inner cavity of the working cylinder from the bottom of the cylinder and connects with the agitator so that the agitator rotates as the rotating end of the drive component rotates.
[0021] Furthermore, the inner cavity of the working cylinder is equipped with a dehydration basket;
[0022] The dehydration basket is located at the top of the stirring component, and the bottom of the dehydration basket is provided with a limiting member for cooperating with the top pressure part. The limiting member is rotatably connected to the dehydration basket.
[0023] When the pressing part abuts against the limiting member in the first rotation direction, the pressing part presses against the limiting member, causing the limiting member to rotate and leaving space for the pressing part to pass through; when the pressing part abuts against the limiting member in the second rotation direction, the pressing part lifts up the limiting member, thereby raising the horizontal height of the limiting member and the dehydration basket.
[0024] The first rotation direction is clockwise, and the second rotation direction is counterclockwise, or the first rotation direction is counterclockwise, and the second rotation direction is clockwise.
[0025] Furthermore, the opening of the working cylinder is provided with a chamber cover and a drive component, a transmission rod, and at least two locking components for locking the chamber cover;
[0026] The rear side of the chamber cover is rotatably connected to the working cylinder body. The chamber cover, which rotates along the working cylinder body, can completely cover the opening of the working cylinder body. The drive component is rotatably connected to the transmission rod. The transmission rod has a forward thread and a reverse thread. One locking component is located in the forward thread section of the transmission rod, and the other locking component is located in the reverse thread section of the transmission rod. When the drive component drives the transmission rod to rotate, the two locking components are threadedly engaged with the transmission rod and approach the chamber cover from the left and right sides respectively to lock the chamber cover.
[0027] Furthermore, insertion holes are provided on the left and right sides of the chamber cover; the locking component includes a transmission block and an insertion block, which are fixedly connected. The transmission block is threadedly engaged with the transmission rod, and the insertion block is recessed inward to form a limiting cavity. The wedge angle formed by the limiting cavity is less than or equal to the friction angle between the insertion block and the insertion hole.
[0028] The beneficial effects of this invention are as follows: by setting up a multi-channel switching valve, the channels connecting to the working cylinder are switched in turn, so that the dehydration solvent chamber and the paraffin chamber are connected to the working cylinder in turn, realizing the rapid switching between the dehydration process and the wax impregnation process. Combined with the liquid pumping structure, the dehydration reagent and paraffin are transported, and the dehydration reagent and paraffin are quickly recovered when the process is switched. Attached Figure Description
[0029] Figure 1 This is a perspective structural schematic diagram of a biological tissue dehydration device according to an embodiment.
[0030] Figure 2 This is a schematic diagram of the structure of a multi-channel switching valve according to one embodiment.
[0031] Figure 3 This is a cross-sectional structural schematic diagram of a multi-channel switching valve according to one embodiment.
[0032] Figure 4 This is a schematic diagram of the structure of an encoding disk according to one embodiment.
[0033] Figure 5 This is a schematic diagram of the structure of a moving valve plate according to one embodiment.
[0034] Figure 6 This is a schematic diagram of the moving valve plate from another angle in one embodiment.
[0035] Figure 7 This is a schematic diagram of the structure of a fixed valve plate according to one embodiment.
[0036] Figure 8 This is a schematic diagram of the internal structure of the working cylinder in one embodiment.
[0037] Figure 9 yes Figure 8 A magnified structural diagram of point A in the middle.
[0038] Figure 10 This is a schematic diagram of the structure of a stirring component according to one embodiment.
[0039] Figure 11 This is a schematic diagram of the surface platform of a biological tissue dehydration device according to an embodiment.
[0040] Figure 12 This is a schematic diagram of the mating structure of the chamber cover and the plug block in one embodiment.
[0041] Figure 13 This is a schematic diagram of the structure of a plug-in block according to one embodiment. Detailed Implementation
[0042] To make the objectives, technical solutions, and advantages of the embodiments of the present invention clearer, the present invention will be further described below in conjunction with the embodiments and accompanying drawings.
[0043] In the description of this invention, it should be understood that the orientation descriptions, such as up, down, front, back, left, right, etc., are based on the orientation or positional relationship shown in the accompanying drawings. They are only for the convenience of describing this invention and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation. Therefore, they should not be construed as limiting this invention.
[0044] In the description of this invention, "several" means an indefinite quantity, "multiple" means two or more, "greater than," "less than," and "exceeding" are understood to exclude the stated number, while "above," "below," and "within" are understood to include the stated number. The use of "first" and "second" in the description is merely for distinguishing technical features and should not be construed as indicating or implying relative importance, or implicitly indicating the number of indicated technical features, or implicitly indicating the order of the indicated technical features. Furthermore, the use of "and / or" throughout the text indicates three parallel solutions; for example, A and / or B indicates a solution satisfied by A, a solution satisfied by B, or a solution satisfied by both A and B.
[0045] In the description of this invention, the terms “comprising,” “including,” or any other variations thereof are intended to cover non-exclusive inclusion, which includes not only the elements listed but also other elements not expressly listed.
[0046] This invention provides a biological tissue dehydration device. For example... Figures 1 to 3 As shown, in one embodiment, the biological tissue dehydration device includes a device body 100 and a working cylinder 200, multiple dehydration solvent chambers 300, multiple paraffin chambers 400, and a multi-channel switching valve 500 assembled in the device body 100.
[0047] The multi-channel switching valve 500 includes a rotary drive assembly 510 and a switching valve body 520. The switching valve body 520 is provided with a first output channel 531 and multiple sets of first input channels 532. The dehydration solvent chamber 300 and the paraffin chamber 400 are respectively connected to the first input channels 532 one by one. The first output channel 531 is connected to the liquid inlet end of the working cylinder 200. A liquid extraction assembly 600 is provided between the first output channel 531 and the liquid inlet end of the working cylinder 200. When the switching valve body 520 and the rotary drive assembly 510 are in drive cooperation, one first output channel 531 can be connected to the corresponding first input channel 532, so that the working cylinder 200 is connected to the corresponding dehydration solvent chamber 300 or paraffin chamber 400. The liquid extraction assembly 600 extracts the contents of the dehydration solvent chamber 300 or paraffin chamber 400 into the working cylinder 200, or discharges the contents of the working cylinder 200 into the dehydration solvent chamber 300 or paraffin chamber 400.
[0048] In actual use, the tissue to be dehydrated is placed in the working cylinder 200 for either dehydration or paraffin impregnation. The operator issues control commands through the human-machine interface of the biological tissue dehydration equipment, specifying whether to proceed with the dehydration or paraffin impregnation process. When dehydration is selected, the multi-channel switching valve 500 connects the working cylinder 200 to the corresponding dehydration solvent chamber 300 via a switching connection. The extraction and discharge assembly 600 then extracts dehydration solvent from the currently connected dehydration solvent chamber 300 into the working cylinder 200, initiating the dehydration process. After the dehydration process is completed, the multi-channel switching valve 500 reconnects the working cylinder 200 and the dehydration solvent chamber 300, and the extraction and discharge assembly 600 discharges the dehydration reagent from the working cylinder 200 into the currently connected dehydration solvent chamber 300, ending the dehydration process. Similarly, during the paraffin impregnation process, the multi-channel switching valve 500 connects the working cylinder 200 to the corresponding paraffin chamber 400, thereby completing the paraffin extraction and discharge steps. After the dehydration and wax impregnation processes are completed, the multi-channel switching valve 500 can connect the working cylinder 200 to the original dehydration solvent chamber 300 (or paraffin chamber 400), or it can connect the working cylinder 200 to another dehydration solvent chamber 300 (or paraffin chamber 400).
[0049] like Figures 2 to 7 As shown, in one embodiment, the multi-channel switching valve 500 further includes an encoder disk 540 and a sensing unit 550. The encoder disk 540 is fixedly connected to the rotating end of the rotary drive assembly 510. The encoder disk 540 is engraved with absolute codes 541 for absolute position and relative codes 542 for relative position. The number of relative codes 542 is an integer multiple of the number of first input channels 532. The number of absolute codes 541 is the same as the number of relative codes 542, and each absolute code 541 and relative code 542 corresponds one-to-one. The sensing unit 550 and the encoder disk 540 are arranged to be relatively movable. The sensing unit 550 detects the absolute codes 541 and relative codes 542 passing through its detection area. When the switching valve body 520 is in transmission cooperation with the rotary drive assembly 510, the first output channel 531 indicated by the absolute and relative positions can be connected to the first input channel 532.
[0050] In this embodiment, the switching valve body 520 is internally provided with a first output channel 531 and multiple sets of first input channels 532. The first output channel 531 can be connected to one of the first input channels 532. Under the rotation of the rotary drive assembly 510, the connection relationship of the rotary drive assembly 510 can be reversed, thereby connecting the first output channel 531 to another first input channel 532. The encoder disk 540 is fixedly connected to the rotating end of the rotary drive assembly 510 and rotates with the rotary drive assembly 510. The absolute code 541 and relative code 542 on the encoder disk 540 are detected by the acquisition sensing detection unit 550, and the rotation angle of the rotary drive assembly 510 is recorded.
[0051] The absolute code 541 and relative code 542 engraved on the encoding disk 540 are distributed in a circle with the center of the encoding disk 540 as the center. There is one absolute code 541 and one relative code 542 on the same diameter. When the sensing detection unit 550 detects each absolute code 541 and relative code 542, it will obtain different detection signals. A first input channel 532 corresponds to one absolute code 541 and one relative code 542. When the sensing detection unit 550 detects the absolute code 541 and relative code 542 corresponding to a first input channel 532, that is, the first input channel 532 is connected to the first output channel 531.
[0052] When the rotary drive assembly 510 drives the switching valve body 520 to rotate, thereby controlling the opening or closing of the first input channel 532 and the first output channel 531, the rotary drive assembly 510 stops when the sensing unit 550 detects the absolute code 541 and relative code 542 on the same diameter. Specifically, when it is necessary to open a first input channel 532 and a first output channel 531, the rotary drive assembly 510 receives a control signal, rotates forward or backward by a certain angle according to the control signal, and then stops, so that the sensing unit 550 detects the absolute code 541 and relative code 542 corresponding to the first input channel 532. When it is necessary to cut off all first input channels 532 and first output channels 531, the rotary drive assembly 510 stops at a position between the two absolute codes 541 (or relative codes 542) corresponding to the first input channels 532. If the number of absolute codes 541 (or relative codes 542) is greater than the number of first input channels 532, an absolute code 541 (or relative code 542) for indicating the cutting off of all first input channels 532 may be set between two absolute codes 541 (or relative codes 542) corresponding to the first input channels 532. When the sensing detection unit 550 identifies the absolute code 541 (or relative code 542) for indicating the cutting off of all first input channels 532, the switching valve body 520 cuts off all first input channels 532.
[0053] In one embodiment, the number of absolute codes 541 is twice the number of first input channels 532, and the number of detection points of absolute codes 541 in the sensing detection unit 550 and the number of first input channels 532 satisfy the following relationship:
[0054] 2 n ≥2P;
[0055] Where n represents the number of detection sites in the absolute code 541, P represents the number of first input channels 532, and P represents the number of binary bits formed by the number of detection sites in the sensing detection unit 550 that are greater than or equal to the number of absolute codes 541.
[0056] Each absolute code 541 is distributed at intervals. Between two absolute codes 541 corresponding to the first input channel 532, an absolute code 541 is set to cut off all first input channels 532. For example, the first absolute code 541 corresponds to the first first input channel 532, the second absolute code 541 corresponds to cutting off all first input channels 532, and the third absolute code 541 corresponds to the second first input channel 532. When the first input channel needs to be turned on, the rotary drive assembly 510 rotates until the first absolute code reaches the detection area of the sensor detection unit 550 and then stops. When all first input channels 532 need to be cut off, the rotary drive assembly 510 rotates until the first absolute code reaches the detection area of the sensor detection unit 550 and then stops. In this embodiment, binary counting is used to identify the absolute code 541. When the detection site of the sensing detection unit 550 detects the absolute code 541, the absolute code 541 blocks the detection light source generated by some detection sites. Only the detection light source emitted by the unblocked detection sites can be received. The number and position of the detection sites blocked by each absolute code 541 are different, thereby generating a corresponding absolute code 541 detection signal, which is converted into a binary virtual signal for recording. For example, if all four detection sites except the first detection site are blocked by the absolute code 541, it can be converted into "1000" to represent the eighth absolute code 541.
[0057] In one embodiment, the biological tissue dehydration device further includes a controller, which is connected to the rotation drive assembly 510 and the sensing unit 550. The encoder disk 540 is also engraved with a zero-position detection point 543 to indicate the zero position. The controller verifies whether the detected relative position reaches a cumulative threshold and whether the detected zero position matches the relative position obtained by detecting the relative code 542 and the position of the zero-position detection point 543. The controller receives detection information from the sensing unit 550 and detects the rotation state of the rotation drive assembly 510. When the zero-position detection point 543 passes through the sensing unit 550, it indicates that the rotation drive assembly 510 has rotated one revolution, and the relative code 542 is cleared and corrected. The controller counts the rotation angle of the rotation drive assembly 510 based on the detection information from the sensing unit 550, determines the absolute position corresponding to the current rotation angle by identifying the absolute code 541, and forms a verification signal by the number of times the zero-position detection point 543 passes through the sensing unit 550 and the detected relative code 542 to determine whether the currently determined absolute position is correct.
[0058] Based on the above embodiments, the controller receives the relative position obtained from the relative code 542 and the zero position obtained from the zero-position detection point 543 detected by the sensing unit 550, and verifies whether the detected relative position reaches the cumulative threshold and whether the detected zero position matches each other. The controller obtains from the sensing unit 550 the number of times the relative code 542 passes through the sensing unit 550 and the number of times the zero-position detection point 543 passes through the sensing unit 550. When the sensing unit 550 detects the zero-position detection point 543, it clears the accumulation of the relative code 542, or when the relative code 542 accumulates to the threshold and is cleared, it controls the sensing unit 550 to detect the zero-position detection point 543 again, ensuring that the accumulation of the relative code 542 and the detection timing of the zero-position detection point match each other.
[0059] In some embodiments, the controller also uses a fault-tolerant mechanism when verifying the absolute code 541 and the relative code 542. The fault-tolerant mechanism is used to determine whether the detection point of the sensing detection unit 550 is damaged and to continue identification and judgment based on the determination that the detection point is damaged.
[0060] After the controller continuously counts and accumulates the relative code 542 to the threshold, when the zero-position detection point 543 is detected passing through the sensing detection unit 550, it is determined that the zero-position detection point 543 is damaged. The controller uses unilateral acquisition of the detection signal of the relative code 542 and counts and accumulates it to determine the relative position, and maintains mutual verification between the absolute code 541 and the relative code 542.
[0061] The sensing unit 550 simultaneously detects two adjacent absolute codes 541 and relative codes 542. When the detection point of any relative code 542 is damaged, the controller can only obtain the detection signal of one of the detection points from the sensing unit 550. The controller determines that the detection point that failed to receive the detection signal is damaged, and identifies the relative code 542 through the remaining detection points of the relative code 542 to maintain the detection of the relative code 542.
[0062] If any detection point of the absolute code 541 is damaged, the binary detection information obtained by the controller based on the detection point is incorrect compared with the information represented by the absolute code 541. The currently obtained binary detection information is the same as the binary detection information obtained on the previous side. The controller infers the absolute code 541 currently entering the sensing detection unit 550 based on the information reflected by the relative code 542, and determines that there is a damaged detection point after the code disk 540 rotates once.
[0063] In one embodiment, the switching valve body 520 includes a valve body housing and a moving valve plate 560 and a fixed valve plate 570 assembled in the valve body housing. The moving valve plate 560 and the fixed valve plate 570 are stacked. The rotary drive assembly 510 is drively connected to the moving valve plate 560. The moving valve plate 560 has a first output common hole 561 at its center and a first input common hole 562 around its periphery. The fixed valve plate 570 has several first input holes 571, which are spaced apart from each other with the first output common hole 561 as the center. The first output common hole 561 is connected to the first output channel 531, and the first input common hole 562 is connected to the first output common hole 561. Each first input hole 571 is connected to each first input channel 532. When the rotary drive assembly 510 drives the moving valve plate 560 to rotate, the first output common hole 561 is connected to one of the first input holes 571 through the first input common hole 562, so that the first output channel 531 is connected to one of the first input channels 532.
[0064] In one embodiment, the switching valve body 520 is further provided with a second output channel 581 and several sets of second input channels 582. The first input channel 532 and the second input channel 582 correspond one-to-one. When the switching valve body 520 is in transmission cooperation with the rotary drive assembly 510, the first output channel 531 indicated by the absolute position and the relative position can be connected to the first input channel 532, and the second output channel 581 can be connected to the second input channel 582.
[0065] The fixed valve plate 570 has a second input hole 572 and a second output common hole 573. An input annular groove 574 is located at the center of the side of the fixed valve plate 570 near the moving valve plate 560. A gas passage groove 563 is located on the side of the moving valve plate 560 near the fixed valve plate 570. The number of second input holes 572 is the same as the number of first input holes 571. Each second input hole 572 is spaced apart from the first output common hole 561, with each second input hole 572 and each first input hole 571 located on the same diameter. One end of the gas passage groove 563 communicates with the input annular groove 574, and the input annular groove 574 communicates with the second output common hole 573. The second output common hole 573 is connected to a second output channel 581. When the rotary drive assembly 510 drives the moving valve plate 560 to rotate, the other end of the gas passage groove 563 communicates with one of the second input holes 572, thus connecting the second output channel 581 with one of the second input channels 582.
[0066] The switching valve body 520 simultaneously connects the first output channel 531 to a first input channel 532 and the second output channel 581 to a second input channel 582. The first input channel 532 can be connected to the contents of the dehydration solvent chamber 300 or the paraffin chamber 400, and the second input channel 582 connects the air pressure between the dehydration solvent chamber 300 or the paraffin chamber 400 and the working cylinder 200, so that the air pressure between the dehydration solvent chamber 300 or the paraffin chamber 400 and the working cylinder 200 is balanced during the transport of the contents.
[0067] like Figures 8 to 10 As shown, in one embodiment, the working cylinder 200 is provided with a stirring element 210 and a drive assembly 220. The stirring element 210 is disposed at the bottom of the inner cavity of the working cylinder 200, and the top of the stirring element 210 is provided with an upwardly protruding pressing part 211. The rotating end of the drive assembly 220 passes through the bottom of the cylinder into the inner cavity of the working cylinder 200 and is connected to the stirring element 210, so that the stirring element 210 rotates as the rotating end of the drive assembly 220 rotates.
[0068] The inner cavity of the working cylinder 200 is equipped with a dehydration basket 230. The dehydration basket 230 is located at the top of the stirring member 210, and the bottom of the dehydration basket 230 is provided with a limiting member 231 for cooperating with the top pressure member 211. The limiting member 231 is rotatably connected to the dehydration basket 230. When the top pressure member 211 abuts against the limiting member 231 in a first rotation direction, the top pressure member 211 presses against the limiting member 231, causing the limiting member 231 to rotate and leaving space for the top pressure member 211 to pass through. When the top pressure member 211 abuts against the limiting member 231 in a second rotation direction, the top pressure member 211 lifts the limiting member 231, thereby raising the horizontal height of the limiting member 231 and the dehydration basket 230. The first rotation direction is clockwise and the second rotation direction is counterclockwise, or the first rotation direction is counterclockwise and the second rotation direction is clockwise.
[0069] In this embodiment, when only stirring of the liquid in the working cylinder 200 is required, the controller drives the stirring element 210 to rotate in the first rotation direction via the drive assembly 220. When the pressing part 211 abuts against the limiting member 231 in the first rotation direction, the limiting member 231 is pressed and rotates. The rotation angle of the limiting member 231 changes with the contact position with the pressing part 211. When the top side of the pressing part 211 contacts the limiting member 231, the limiting member 231 rotates to its maximum angle. At this time, the limiting member 231 completely avoids the pressing part 211, leaving space for the pressing part 211 to pass through, and the pressing part 211 will not push up the dehydration basket 230. When it is necessary to stir the dehydration reagent and shake off the water on the tissue to be dehydrated, The control drive assembly 220 drives the stirring component 210 to rotate in the second rotation direction. When the pressing part 211 abuts against the limiting part 231 in the second rotation direction, the limiting part 231 does not rotate or the rotation amplitude is less than the rotation amplitude of the pressing part 211 when it passes in the first rotation direction, so that the pressing part 211 cannot pass directly. The pressing part 211 lifts the limiting part 231, thereby raising the horizontal height of the limiting part 231 and the dehydration basket 230. After the pressing part 211 passes, the dehydration basket 230 and the pressing part 211 fall back to the original horizontal height. In the repeated lifting and falling process, the dehydration basket 230 is in a state of periodic shaking, and the water on the dehydrated tissue is quickly shaken off, thus achieving the effect of shaking off water and stirring the dehydration reagent.
[0070] like Figures 11 to 13 As shown, in one embodiment, the opening of the working cylinder 200 is provided with a chamber cover 710, a drive member 720, a transmission rod 730, and at least two locking members 740 for locking the chamber cover 710. The rear side of the chamber cover 710 is rotatably connected to the working cylinder 200, and the chamber cover 710, which rotates along the working cylinder 200, can completely cover the opening of the working cylinder 200; the drive member 720 is rotatably connected to the transmission rod 730, which has a forward thread and a reverse thread; one locking member 740 is located on the forward thread section of the transmission rod 730, and the other locking member 740 is located on the reverse thread section of the transmission rod 730. When the drive member 720 drives the transmission rod 730 to rotate, the two locking members 740 are threadedly engaged with the transmission rod 730, and approach the chamber cover 710 from the left and right sides respectively and lock the chamber cover 710.
[0071] In this embodiment, the chamber cover 710 has insertion holes 711 on both the left and right sides; the locking member 740 includes a transmission block 741 and an insertion block 742, which are fixedly connected. The transmission block 741 is threadedly engaged with the transmission rod 730. The insertion block 742 is recessed inward to form a limiting cavity 743. The wedge angle formed by the limiting cavity 743 is less than or equal to the friction angle between the insertion block 742 and the insertion hole 711.
[0072] In this embodiment, the transmission rod 730 is located on the front side of the chamber cover 710. The locking member 740 installed on the transmission rod 730 can contact the left or right side of the chamber cover 710 when it is close to the chamber cover 710. Specifically, when it is necessary to lock the chamber cover 710, the chamber cover 710 is closed so that it covers the opening of the working cylinder 200. The drive member 720 is activated, causing the drive member 720 to drive the transmission rod 730 to rotate clockwise or counterclockwise. The two locking members 740 are threadedly engaged with the rotating transmission rod 730 and gradually move towards the chamber cover 710, thereby locking the chamber cover 710 by contacting it. Conversely, when it is necessary to unlock the chamber cover 710, the drive member 720 is activated, causing the drive member 720 to drive the transmission rod 730 to rotate in the opposite direction to when locking the chamber cover 710. The two locking members 740 are threadedly engaged with the rotating transmission rod 730 and gradually move away from the chamber cover 710, thereby unlocking the chamber cover 710.
[0073] The above description is merely a specific embodiment of the present invention, but the scope of protection of the present invention is not limited thereto. Any variations or substitutions that can be easily conceived by those skilled in the art within the technical scope disclosed in the present invention should be included within the scope of protection of the present invention. Therefore, the scope of protection of the present invention should be determined by the scope of the claims.
Claims
1. A biological tissue dehydration device, comprising a device body and a working cylinder, multiple dehydration solvent chambers, and a paraffin chamber assembled within the device body, characterized in that, It also includes multi-channel switching valves; The multi-channel switching valve includes a rotary drive assembly and a switching valve body. The switching valve body is provided with a first output channel and multiple sets of first input channels. The dehydration solvent chamber and the paraffin chamber are respectively connected to the first input channels. The first output channel is connected to the liquid inlet end of the working cylinder. A liquid extraction assembly is provided between the first output channel and the liquid inlet end of the working cylinder. When the switching valve body is in transmission cooperation with the rotary drive assembly, the first output channel can be connected to the first input channel, so that the working cylinder is connected to the corresponding dehydration solvent chamber or paraffin chamber. The pumping liquid assembly pumps the contents of the dehydration solvent chamber or paraffin chamber into the working cylinder, or discharges the contents of the working cylinder into the dehydration solvent chamber or paraffin chamber. The switching valve body includes a valve body shell and a moving valve plate and a fixed valve plate assembled inside the valve body shell. The moving valve plate and the fixed valve plate are stacked. The rotary drive assembly is drivenly connected to the moving valve plate. The moving valve plate has a first output common hole at its center, and a first input common hole is provided around the first output common hole. The fixed valve plate has a plurality of first input holes, and each first input hole is distributed at intervals around the first output common hole. The first output common hole is connected to the first output channel, the first input common hole is connected to the first output common hole, and each first input hole is connected to each first input channel. When the rotary drive component drives the moving valve plate to rotate, the first output common hole is connected to one of the first input holes through the first input common hole, so that the first output channel is connected to one of the first input channels. The switching valve body is also provided with a second output channel and several sets of second input channels. The first input channel and the second input channel correspond one-to-one. When the switching valve body is in transmission cooperation with the rotary drive assembly, the first output channel indicated by the absolute position and the relative position can be connected to the first input channel and the second output channel can be connected to the second input channel. The fixed valve plate has a second input hole and a second common output hole. The fixed valve plate has an input ring groove at its center on the side near the moving valve plate, and the moving valve plate has a gas passage groove on the side near the fixed valve plate. The number of second input holes is the same as the number of first input holes. The second input holes are distributed at intervals with the first common output hole as the center. A second input hole and a first input hole are located on the same diameter. One end of the gas passage groove is connected to the input ring groove, and the input ring groove is connected to the second common output hole. The second common output hole is connected to a second output channel. When the rotary drive assembly drives the moving valve plate to rotate, the other end of the gas passage groove is connected to one of the second input holes, so that the second output channel is connected to one of the second input channels.
2. The biological tissue dehydration device according to claim 1, characterized in that, The multi-channel switching valve also includes an encoder and a sensor detection unit; The encoder disk is fixedly connected to the rotating end of the rotary drive assembly. The encoder disk is engraved with absolute codes for representing absolute positions and relative codes for representing relative positions. The number of relative codes is an integer multiple of the number of the first input channels. The number of absolute codes is the same as the number of relative codes, and the absolute codes and relative codes correspond one-to-one. The sensing unit and the encoding disk are arranged to be relatively movable, and the sensing unit detects the absolute and relative codes passing through its detection area; When the switching valve body is in transmission cooperation with the rotary drive assembly, the first output channel indicated by the absolute position and the first input channel can be connected accordingly.
3. The biological tissue dehydration device according to claim 2, characterized in that, The number of absolute codes is twice the number of the first input channels, and the number of absolute code detection points of the sensing detection unit and the number of the first input channels satisfy the following relationship: ; Where n represents the number of absolute coding detection sites, and P represents the number of first input channels.
4. The biological tissue dehydration device according to claim 2, characterized in that, The biological tissue dehydration device also includes a controller, which is connected to the rotation drive assembly and the sensing and detection unit. The encoder disk is also engraved with zero-position detection points to indicate the zero position. The controller verifies whether the detected relative position reaches the cumulative threshold and whether the detected zero position matches each other based on the relative position obtained by detecting the relative encoding and the position of the zero-position detection point.
5. The biological tissue dehydration device according to claim 1, characterized in that, The working cylinder is equipped with a stirring component and a drive assembly; The stirring element is disposed at the bottom of the inner cavity of the working cylinder. The top of the stirring element is provided with an upwardly protruding pressing part. The rotating end of the driving component passes through the bottom of the cylinder into the inner cavity of the working cylinder and is connected to the stirring element so that the stirring element rotates with the rotating end of the driving component.
6. The biological tissue dehydration device according to claim 5, characterized in that, The inner cavity of the working cylinder is equipped with a dehydration basket; The dehydration basket is located at the top of the stirring component, and the bottom of the dehydration basket is provided with a limiting member for cooperating with the top pressing part. The limiting member is rotatably connected to the dehydration basket. When the pressing part abuts against the limiting member in the first rotation direction, the pressing part presses against the limiting member, causing the limiting member to rotate and leaving space for the pressing part to pass through; when the pressing part abuts against the limiting member in the second rotation direction, the pressing part lifts the limiting member, thereby raising the horizontal height of the limiting member and the dehydration basket. The first rotation direction is clockwise and the second rotation direction is counterclockwise, or the first rotation direction is counterclockwise and the second rotation direction is clockwise.
7. The biological tissue dehydration device according to claim 1, characterized in that, The opening of the working cylinder is provided with a chamber cover, a drive component, a transmission rod, and at least two locking components for locking the chamber cover; The rear side of the chamber cover is rotatably connected to the working cylinder body, and the chamber cover, which rotates along the working cylinder body, can completely cover the opening of the working cylinder body; the driving member is rotatably connected to the transmission rod, and the transmission rod has a forward thread and a reverse thread. One of the locking members is located in the forward thread section of the transmission rod, and the other locking member is located in the reverse thread section of the transmission rod. When the driving member drives the transmission rod to rotate, the two locking members are threadedly engaged with the transmission rod, and approach the chamber cover from the left and right sides respectively and lock the chamber cover.
8. The biological tissue dehydration device according to claim 7, characterized in that, The chamber cover has insertion holes on both the left and right sides; the locking component includes a transmission block and an insertion block, the transmission block and the insertion block are fixedly connected, the transmission block is threadedly engaged with the transmission rod, the insertion block is recessed inward to form a limiting cavity, and the wedge angle formed by the limiting cavity is less than or equal to the friction angle between the insertion block and the insertion hole.
Citation Information
Patent Citations
Dewatering equipment for biology organization
CN201247176Y
Multichannel valve position coding device
CN205066784U
Biological tissue dehydration equipment
CN217006591U