Method for producing a stent

Abstract

The present application provides a stent preparation method, which can avoid the free end of the braided wire being located at the proximal end or distal end of the stent to easily prick the blood vessel and auxiliary instrument.

Description

Technical Field

[0001] This invention belongs to the field of medical device technology, and specifically relates to a method for preparing a stent. Background Technology

[0002] With the aging of society, the incidence of cardiovascular diseases is constantly rising, among which aortic system diseases, including aortic aneurysm and aortic dissection, are highly prevalent and critical. Currently, the most common treatment for aortic diseases is endovascular interventional therapy. Endovascular interventional therapy uses radiation equipment to insert a covered stent into the aortic lesion, thereby restoring blood flow to the vessel.

[0003] The covered stent consists of two parts: a metal skeleton and a covering. There are usually two technical approaches to the metal skeleton: one is to cut metal tubes, and the other is to weave metal wires.

[0004] After the metal wires are braided and then heat-treated for shaping, it is inevitable that metal wire ends will be formed at both ends of the stent. If this is not treated, after the covered stent is implanted into the human body, the metal wire ends may puncture the covered stent and then injure the blood vessels as the blood vessels pulsate. Summary of the Invention

[0005] The objective of this invention is to at least prevent the free ends of the braided filaments from being located near the proximal or distal end of the stent, thus avoiding potential vascular punctures. This objective is achieved through the following means:

[0006] A method for fabricating a stent, the stent comprising a mid-wavelength coil and a proximal-wavelength coil, or the mid-wavelength coil and a distal-wavelength coil, comprising the following steps:

[0007] The first end of the first filament is fixed, and the second end of the first filament is woven around the axis of the bracket. The second end of the first filament completes at least one loop of weaving to form the middle wave loop of the first section. The second end of the first filament wraps around and fixes the first end of the first filament to the middle wave loop of the first section to form a first fixing knot.

[0008] The second end of the first filament is extended to the distal or proximal end and woven around the axis of the support at a position adjacent to the axial direction of the middle wave loop of the first section. The second end of the first filament completes at least one lap of weaving to form the middle wave loop of the second section, wherein the middle wave loop of the second section is axially adjacent to the middle wave loop of the first section.

[0009] Continue to extend the second end of the first filament towards the far end or near end, and weave it sequentially according to the weaving method of the middle wave loop of the second section until the last middle wave loop is formed;

[0010] After the last section of the middle wave loop is completed, the second end of the first filament is wound around any one of the middle wave loops to form a second fixed knot.

[0011] The first end of the second filament is wound and fixed on any of the middle bevels to form a third fixing knot. The second end of the second filament is extended to the proximal or distal end and then woven around the axis of the support. The second end of the second filament completes at least one loop of weaving to form the proximal bevel or the distal bevel. The proximal bevel or the distal bevel is adjacent to the middle bevel of the first section and located at the proximal or distal end of the middle bevel of the first section. The second end of the second filament is then wound and fixed on any of the middle bevels to form a fourth fixing knot.

[0012] In one embodiment, the preparation method further includes:

[0013] The first end of the third filament is wound and fixed around any one of the middle bevels to form a fifth fixing knot. The second end of the third filament is extended distally or proximally and then woven around the axis of the support. The second end of the third filament completes at least one loop of weaving to form the distal or proximal bevel, wherein the distal or proximal bevel is adjacent to the middle bevel of the last section and located at the distal or proximal end of the middle of the last section. The second end of the third filament is then wound and fixed around any one of the middle bevels to form a sixth fixing knot.

[0014] The middle wave loop is located between the proximal wave loop and the distal wave loop. When the second filament forms the proximal wave loop, the third filament forms the distal wave loop; when the second filament forms the distal wave loop, the third filament forms the proximal wave loop.

[0015] In one embodiment, the central waveband has multiple first filaments with different diameters, and the first end and the second end of each first filament are fixed to any one of the central wavebands.

[0016] In one embodiment, at least one of the first fixing knot, the second fixing knot, the third fixing knot, the fourth fixing knot, the fifth fixing knot, and the sixth fixing knot is at least partially wrapped with a thread or film or partially covered with a connector.

[0017] In one embodiment, the line or the film is reproducible.

[0018] In one embodiment, the connector includes a first component and a second component, the first component and the second component are fixedly connected, and a first end of the first filament, a second end of the first filament, a first end of the second filament, a second end of the second filament, a first end of the third filament, or a second end of the third filament is disposed between the first component and the second component.

[0019] In one embodiment, the maximum width of the connector in the axial direction is 1.5 to 3 times the diameter of the first wire, the second wire, or the third wire.

[0020] In one embodiment, the first component includes a first protrusion and a first groove, and the second component further includes a second protrusion and a second groove, wherein the first protrusion and the second groove are connected to each other in a cooperative manner, and the second protrusion and the first groove are connected to each other in a cooperative manner; or, the first component and the second component are connected by welding.

[0021] In one embodiment, the material of the connector includes a reproducible metallic material.

[0022] In one embodiment, the connector has a smooth outer surface.

[0023] According to the above-mentioned stent preparation method, by placing the first, second, third, and fourth fixation knots on the middle wavelet, and the proximal or distal wavelet adjacent to the middle wavelet of the first segment and located at the proximal or distal end of the middle wavelet of the first segment, the aforementioned fixation knots are not placed on the proximal or distal wavelet. That is, the first and second ends of the corresponding wire are not placed on the proximal or distal wavelet, thereby preventing the proximal or distal end of the stent from being exposed by the free end of the wire, thus avoiding puncture of blood vessels. Attached Figure Description

[0024] Various other advantages and benefits will become apparent to those skilled in the art upon reading the following detailed description of preferred embodiments. The accompanying drawings are for illustrative purposes only and are not intended to limit the invention. Furthermore, the same reference numerals denote the same parts throughout the drawings. Wherein:

[0025] Figure 1 This is a partial schematic diagram of the completed braiding of a support structure according to one embodiment.

[0026] Figure 2 A partial schematic diagram of the completed braiding of a support provided in another embodiment.

[0027] Figure 3 This is a schematic diagram of a connector being attached to a waveguide according to one embodiment.

[0028] Figure 4 This is a schematic diagram of a connector provided in one embodiment and a schematic diagram of the cross section B of the connector 30 with the maximum axial dimension.

[0029] Figure 5 This is a schematic diagram of the first component in a connector provided in one embodiment at different angles.

[0030] Figure 6 A schematic diagram of a connector provided for another embodiment.

[0031] Figure 7 Schematic diagrams of different angles of the second component in a connector provided for another embodiment. Detailed Implementation

[0032] Exemplary embodiments of the invention will now be described in more detail with reference to the accompanying drawings. While exemplary embodiments of the invention are shown in the drawings, it should be understood that the invention can be implemented in various forms and should not be limited to the embodiments set forth herein. Rather, these embodiments are provided to enable a more thorough understanding of the invention and to fully convey the scope of the invention to those skilled in the art.

[0033] It should be understood that the terminology used herein is for the purpose of describing particular exemplary embodiments only and is not intended to be limiting. Unless the context clearly indicates otherwise, the singular forms “a,” “an,” and “described” as used herein may also include the plural forms. The terms “comprising,” “including,” “containing,” and “having” are inclusive and therefore indicate the presence of the stated features, steps, operations, elements, and / or components, but do not exclude the presence or addition of one or more other features, steps, operations, elements, components, and / or combinations thereof. The method steps, processes, and operations described herein are not construed as requiring them to be performed in a particular order described or illustrated unless the order of performance is explicitly indicated. It should also be understood that additional or alternative steps may be used.

[0034] Although terms such as first, second, third, etc., may be used in this document to describe multiple elements, components, regions, layers, and / or segments, these elements, components, regions, layers, and / or segments should not be limited by these terms. These terms may be used only to distinguish one element, component, region, layer, or segment from another. Unless the context clearly indicates otherwise, terms such as "first," "second," and other numerical terms used herein do not imply order or sequence. Therefore, the first element, component, region, layer, or segment discussed below may be referred to as the second element, component, region, layer, or segment without departing from the teachings of the exemplary embodiments.

[0035] For ease of description, spatial relative terms may be used in the text to describe the relationship of one element or feature relative to another element or feature, as shown in the figure. These relative terms include, for example, "inside," "outside," "middle," "outer," "below," "below," "above," "over," etc. Such spatial relative terms are intended to include different orientations of the device in use or operation, other than those depicted in the figure. For example, if the device in the figure is flipped, an element described as "below other elements or features" or "below other elements or features" would subsequently be oriented as "above other elements or features" or "above other elements or features." Therefore, the example term "below" can include both upper and lower orientations. The device may be otherwise oriented (rotated 90 degrees or in other directions), and the spatial relative descriptors used in the text will be interpreted accordingly.

[0036] It should be noted that the terms "distal" and "proximal" are used as directional terms in the field of interventional medical devices. "Proximal" refers to the end closer to the heart, while "distal" refers to the end farther from the heart. Blood flows from the heart, first through the proximal end and then to the distal end.

[0037] This embodiment provides a method for preparing a stent 100, including the following steps:

[0038] S101: Fix the first end of the first filament, weave the second end of the first filament around the axis of the bracket, and complete at least one loop of weaving to form a first section of the middle wave loop. The second end of the first filament is wrapped around the first section of the middle wave loop, and the first end of the first filament is fixed to form a first fixed knot.

[0039] See Figure 1 In this embodiment, the mold 1 is a pre-processed fixed structure. The mold 1 is cylindrical in shape and has several protruding structures 80. These protruding structures 80 are located at the crests and troughs of the support to facilitate the hooking and weaving of the wire, thereby forming the structure of the support 100. It should be noted that the space between adjacent crests and troughs is a wave rod.

[0040] In step S101, the first filament 700 has a first end 701 and a second end 702. Starting from the protruding structure 80a, the first end 701 is fixed at the starting point. The second end 702 is hooked onto the protruding structure 80 in sequence along the horizontal direction around the axis of the support. The first filament 700 completes at least one loop of weaving, forming a first section of the middle wave loop 70A. In this embodiment, after completing one loop of weaving, the second end 702 returns to the starting point protruding structure 80a, and then continues in the weaving direction, winding around the already formed first section of the middle wave loop 70A to form a first fixing knot 703. The winding of the first fixing knot 703 can fix the first end 701 of the first filament 700. Figure 1 In order to facilitate weaving, the first end 701 of the first filament 700 has a long protruding thread. By simply cutting the part of the first filament 700 near the first end 701 at the protruding structure 80a, the first end 701 of the new first filament 700 can be fixed in the first fixing knot 703.

[0041] In this embodiment, the first fixing knot 703 is V-shaped, with its two ends located on protruding structures 80a and 80b at two adjacent troughs, and its tip located at a crest between the two adjacent troughs. In other embodiments, the two ends of the V-shape are located at two adjacent crests, and the tip of the V-shape is located at a trough between the two adjacent crests; or the V-shape may be an asymmetrical structure. The shape of the first fixing knot 703 may also be linear, dotted, or W-shaped, etc.

[0042] S102: Extend the second end of the first filament toward the distal or proximal end, and weave it around the axis of the bracket at a position adjacent to the axial direction of the middle wave loop of the first section. The second end of the first filament completes at least one loop of weaving to form the middle wave loop of the second section, wherein the middle wave loop of the second section is axially adjacent to the middle wave loop of the first section.

[0043] In step S102, in this embodiment, the second end 702 of the first filament 700 extends downward along the wave bar 81 at the protruding structure 80b, wherein the downward direction can be towards the distal end or towards the proximal end. At the axially adjacent position of the middle wave loop 70A of the first section (that is, the position of the middle wave loop 70B of the second section), the second end 702 of the first filament 700 hooks onto the protruding structure 80 sequentially along the horizontal direction around the axis of the support, completing at least one loop of weaving to form the middle wave loop 70B of the second section. In this embodiment, exactly one loop of weaving is completed. It can be understood that the starting point of the middle wave loop 70B of the second section is the protruding structure 80b, and after the second end 702 of the first filament 700 completes one loop of weaving, it returns to the starting point.

[0044] In order to connect the first section of the middle wave loop 70A and the second section of the middle wave loop 70B, when weaving the second section of the middle wave loop 70B, when the first filament 700 hooks onto the protruding structure 80, the second section of the middle wave loop 70B and the first section of the middle wave loop 70A intersect at the point of overlap of the first section of the middle wave loop 70A and the second section of the middle wave loop 70B (that is, at the corresponding protruding structure 80).

[0045] S103: Continue to extend the second end of the first filament towards the far end or near end, and weave it sequentially according to the weaving method of the middle wave loop of the second section until the last middle wave loop is formed.

[0046] In step S103, the second end 702 of the first filament 700 continues to extend downwards, and following the weaving pattern of the second section's middle wave loop 70B, the third section's middle wave loop 70C, and so on, are woven sequentially until the last section's middle wave loop is formed. The number of middle wave loops (sections) can be set according to requirements.

[0047] S104: After the last section of the middle wave loop is completed, the second end of the first filament is wound around any one of the middle wave loops to form a second fixed knot.

[0048] In step S104, the second fixing knot (not shown in the figure) has the same shape as the first fixing knot 703. Steps S101 to S104 are mainly used for weaving to form the central wave loop.

[0049] S105: The first end of the second filament is wound and fixed on any of the middle bevels to form a third fixing knot. The second end of the second filament is extended to the proximal or distal end and then woven around the axis of the support. The second end of the second filament completes at least one loop of weaving to form a proximal or distal bevel, wherein the proximal or distal bevel is adjacent to the middle bevel of the first section and located at the proximal or distal end of the middle bevel of the first section. The second end of the second filament is then wound and fixed on any of the middle bevels to form a fourth fixing knot.

[0050] In step S105, at Figure 1 In this embodiment, the second filament 600 includes a first end 601 and a second end 602. The first end 601 of the second filament 600 is wound and fixed on any middle bevel. In this embodiment, the first end 601 of the second filament is wound and fixed on the middle bevel 70A of the first section to form a third fixed knot 603.

[0051] The third fixing knot 603 begins at a protruding structure 80c and ends at a protruding structure 80d. The second end 602 of the second filament 600 extends upward from the protruding structure 80d, and the upward direction can be towards the proximal end or towards the distal end.

[0052] Then, the second end 602 of the second filament 600 is hooked onto the protruding structure 80 sequentially along the horizontal direction around the axis of the support, completing at least one loop of weaving to form a proximal or distal wave loop. In this embodiment, exactly one loop of weaving is completed, forming a proximal wave loop 60A, and the second end 602 of the second filament 600 returns to the protruding structure 80d. This proximal wave loop 60A is adjacent to and located near the proximal end of the first section's middle wave loop 70A. It is understood that... Figure 1 The 60A in the text can also be a far-end waveband.

[0053] After forming the near-end wave loop 60A, the second end 602 of the second filament 600 can be wound and fixed onto any one of the middle wave loops to form a fourth fixing knot. In this embodiment, the second end 602 of the second filament 600 extends downward from the protruding structure 80d and is wound and fixed onto the middle wave loop 70A of the first section to form a fourth fixing knot 604. The fourth fixing knot 604 begins at the protruding structure 80d and ends at the protruding structure 80e.

[0054] It should be noted that the various shape variations of the third fixing knot 603 and the fourth fixing knot 604 can be found in the first fixing knot 703. Figure 1 In order to facilitate weaving, the two ends of the second filament 600 have long protruding threads. By simply cutting the part of the second filament 600 near the first end 601 at the protruding structure 80c, the first end 601 of the new second filament 600 can be fixed in the third fixing knot 603. Similarly, by simply cutting the part of the second filament 600 near the second end 602 at the protruding structure 80e, the second end 602 of the new second filament 600 can be fixed in the fourth fixing knot 604.

[0055] According to steps S101-S105, a stent 100 with a mid-wavelength coil 70 and a proximal wavelength coil 60A, or a stent 100 with a mid-wavelength coil 70 and a distal wavelength coil (not shown), can be prepared. In the stent 100 with a mid-wavelength coil 70 and a proximal wavelength coil 60A, the free ends of the filaments (first end and second end) on the proximal side are not located at the proximal end of the stent 100, thereby preventing the free ends of the filaments from protruding from the proximal end of the stent 100 and thus avoiding puncture of blood vessels. Similarly, in the stent 100 with a mid-wavelength coil and a distal wavelength coil, the free ends of the filaments (first end and second end) on the distal side are not located at the distal end of the stent 100, thereby preventing the free ends of the filaments from protruding from the distal end of the stent 100 and thus avoiding puncture of blood vessels. Because the first and last segments of the stent have the highest degree of freedom, if there are free ends of wires on them, the risk of puncturing blood vessels or interfering with the device (chimney technique) would be very high. Moving the free ends of the wires to the middle wavelet position greatly reduces the risk.

[0056] In one embodiment, the method for preparing the stent further includes step S106: First end of the third filament is wound and fixed on any one of the central wave loops to form a fifth fixing knot; second end of the third filament is extended distally or proximally and then woven around the axis of the stent, with the second end of the third filament completing at least one loop to form the distal wave loop or the proximal wave loop, wherein the distal wave loop or the proximal wave loop is adjacent to the last central wave loop and located at the distal or proximal end of the last section; then, the second end of the third filament is wound and fixed on any one of the central wave loops to form a sixth fixing knot. The central wave loop is located between the proximal wave loop and the distal wave loop; when the second filament forms the proximal wave loop, the third filament forms the distal wave loop; when the second filament forms the distal wave loop, the third filament forms the proximal wave loop.

[0057] Step S106 involves further weaving a distal or proximal wavering loop based on steps S101-S105. (See attached image) Figure 2 At this time, the stent 100 includes a proximal wavering coil 60A, a middle wavering coil 70, and a distal wavering coil 60B. When the proximal wavering coil is prepared in step S105, the distal wavering coil is prepared in step S106; when the distal wavering coil is prepared in step S105, the proximal wavering coil is prepared in step S106.

[0058] The third filament 800 includes a first end 801 and a second end 802. The first end 801 of the third filament 800 is wound and fixed on any one of the middle bevels 70. In this embodiment, the first end 801 of the third filament 800 is wound and fixed on the last middle bevel 70N and the penultimate middle bevel 70M to form a fifth fixing knot 803, wherein the fifth fixing knot 803 is a straight structure wound around two bevels. The starting point of the fifth fixing knot 803 is a protruding structure 80f, and the ending point of the fifth fixing knot 803 is a protruding structure 80g. The second end 802 of the third filament 800 extends downward from the protruding structure 80g, wherein the downward direction can be towards the proximal end or towards the distal end.

[0059] Then, the second end 802 of the third filament 800 is hooked onto the protruding structure 80 in sequence along the horizontal direction around the axis of the support, completing at least one loop of weaving to form a proximal or distal wave loop. In this embodiment, exactly one loop of weaving is completed, forming a distal wave loop 60B, and the second end 802 of the third filament 800 returns to the protruding structure 80g. This distal wave loop 60B is adjacent to and located at the distal end of the last section's middle wave loop 70N. It is understood that... Figure 1 The 70N in the text can also be a near-end wave loop.

[0060] After forming the distal wave loop 60B, the second end 802 of the third filament 800 can be wound and fixed onto any one of the middle wave loops to form a sixth fixing knot. In this embodiment, the second end 802 of the third filament 800 extends upward from the protruding structure 80g and is wound and fixed onto the last middle wave loop 70N and the penultimate middle wave loop 70M to form a sixth fixing knot 804. The sixth fixing knot 804 begins at the protruding structure 80g and ends at the protruding structure 80h.

[0061] It should be noted that the various shape variations of the fifth fixing knot 803 and the sixth fixing knot 804 can be found in the first fixing knot 703. Figure 1 In order to facilitate weaving, the two ends of the third wire 800 have long protruding wires. By simply cutting the part of the third wire 800 near the first end 801 at the protruding structure 80f, the first end 801 of the new third wire 800 can be fixed in the fifth fixing knot 803. Similarly, by simply cutting the part of the third wire 800 near the second end 802 at the protruding structure 80h, the second end 802 of the new third wire 800 can be fixed in the sixth fixing knot 804.

[0062] In this embodiment, the diameters of the first wire 700, the second wire 600, and the third wire 800 can be the same or different. To further satisfy the requirement of different radial forces in the axial direction of the support, the central corrugated coil 70 has multiple first wires 700, each with a different diameter. See also... Figure 2 At the point where the wire diameter varies in the middle of the support 100, it can be seen that... Figure 2 Two first wires 700 are used. The first end and the second end of each first wire are fixed to any one of the middle beaded loops 70. The fixing method can refer to the fixing method of each wire mentioned above.

[0063] In one embodiment, the method for fabricating the stent further includes heat setting. During this heat setting process, the free ends (first end and second end) of each wire can be shaped to face the inner surface of the stent body to avoid puncturing the blood vessel wall.

[0064] In one embodiment, the method for preparing the scaffold further includes coating the surface of the woven scaffold with a film.

[0065] In one embodiment, to further reduce the risk of the wire tip piercing the blood vessel wall, at least one of the first, second, third, fourth, fifth, and sixth fixing knots is at least partially wrapped with thread or membrane, or uses a connector 30 (see...) Figure 3 Partial coating is performed. Specifically, the thread can be selected from PTFE thread, polyester suture thread, polypropylene suture thread, or nylon suture thread, etc. The membrane can be selected from PTFE membrane or PET membrane. The thread or membrane is reproducible, specifically, barium sulfate is added to the material of the thread or membrane.

[0066] Furthermore, in one embodiment, when one or more of the first, second, third, fourth, fifth, and sixth fixing knots are disposed on the middle wave loop of the first section or the middle wave loop of the last section, they can be wrapped with a photoreflective thread or film to form a V-shaped knot, making the V-shaped knot photoreflective. This V-shaped knot can also be used to indicate the proximal and distal ends of the support. In other embodiments, regardless of whether one or more of the first, second, third, fourth, fifth, and sixth fixing knots are disposed on any middle wave loop, they can all be wrapped with a photoreflective thread or film to form a V-shaped knot.

[0067] The specific operations are as follows: the first fixing knot is formed by wrapping it with thread or film to form a V-shaped knot; or / and, when the second fixing knot is located on the middle wave loop of the last section, the second fixing knot is formed by wrapping it with thread or film to form a V-shaped knot; or / and, when the third fixing knot is located on the middle wave loop of the first section, the third fixing knot is formed by wrapping it with thread or film to form a V-shaped knot; or / and, when the fourth fixing knot is located on the middle wave loop of the first section, the fourth fixing knot is formed by wrapping it with thread or film to form a V-shaped knot; or / and, when the fifth fixing knot is located on the middle wave loop of the last section, the fifth fixing knot is formed by wrapping it with thread or film to form a V-shaped knot; or / and, when the sixth fixing knot is located on the middle wave loop of the last section, the sixth fixing knot is formed by wrapping it with thread or film to form a V-shaped knot.

[0068] In this embodiment, Figure 3 In the middle, the connector 30 has a smooth outer surface, which can be ellipsoidal, spherical or other smooth-surfaced shapes, which can also avoid damage to the membrane and blood vessels.

[0069] In this embodiment, the maximum axial width of the connector 30 is 1.5 to 3 times the diameter of the wire. This design avoids the connector 30 being too large, which would increase the overall compression diameter of the support; and avoids the connector being too small, which would not be able to properly fix the free end of the wire. It should be noted that, for example, when the connector 30 is ellipsoidal, the axial direction of the connector is the major axis direction of the ellipsoid, and the maximum axial width is the maximum width in the major axis direction of the ellipsoid; when the connector 30 is spherical, the maximum axial width of the connector is the same as its diameter.

[0070] See Figure 4 The connector 30 includes a first component 301 and a second component 302, which are fixedly connected. The first end 701 of the first wire 700, the second end 702 of the first wire 700, the first end 601 of the second wire 600, the second end 602 of the second wire 600, and the first end 801 or the second end 802 of the third wire 800 are disposed between the first component 301 and the second component 302.

[0071] See Figure 5 The first component 301 includes a first groove 301A and a second groove 301B. It is understood that the second component 302 includes a third groove and a fourth groove, combined with... Figure 4When the first component 301 and the second component 302 are brought close together and connected, the first groove 301A and the third groove form the first channel 4, and the second groove 301B and the fourth groove form the second channel 5. In this embodiment, the free ends (first end and second end) of the filament are both fixed by being wound around the corresponding corrugated coils. The first channel 4 can hold the free ends of the filament, and the second channel 5 can hold the corresponding corrugated coils, so that the free ends of the filament are covered and fixed within the connector 30.

[0072] In this embodiment, the first groove 301A, the second groove 301B, the third groove, and the fourth groove are all arranged along the axial direction of the connector. In other embodiments, the first groove 301A, the second groove 301B, the third groove, and the fourth groove can be arranged in any direction, as long as they can fix the free end of the wire. The first channel 4 and / or the second channel 5 penetrates the connector 30. In other embodiments, one end of the first channel 4 penetrates the connector 30, and the other end is located inside the connector 30.

[0073] In this embodiment, the first component 301 and the second component 302 are connected by welding.

[0074] In other embodiments, see Figure 6 and Figure 7 The first component 301 further includes a first protrusion 301C and a first groove 301D, and the second component 302 further includes a second protrusion 302C and a second groove 302D. The first protrusion 301C and the second groove 302D are connected to each other, and the second protrusion 302C and the first groove 301D are also connected to each other. In this embodiment, welding is not required. The first protrusion 301C and the second groove 302D are both interference fits, so the specific method used is riveting. Compared to welding, riveting can reduce the overall size of the connector.

[0075] In embodiments of the present invention, the connector 30 is made of a reproducible metallic material, such as tantalum, gold, or a platinum-iridium alloy. By using a reproducible material for the connector, positioning can be achieved without the need for additional reproducible points.

[0076] The above description is merely a preferred embodiment of the present invention, but the scope of protection of the present invention is not limited thereto. Any variations or substitutions that can be easily conceived by those skilled in the art within the technical scope disclosed in the present invention should be included within the scope of protection of the present invention. Therefore, the scope of protection of the present invention should be determined by the scope of the claims.

Claims

1. A method for fabricating a stent, the stent comprising a middle waveguide, a distal waveguide, and a proximal waveguide, characterized in that, Includes the following steps: The first end of the first filament is fixed, and the second end of the first filament is woven around the axis of the bracket. The second end of the first filament completes at least one loop of weaving to form the first section of the middle wave loop. The second end of the first filament returns to the starting point and is wound around the first section of the middle wave loop to form a V-shaped first fixing knot. The winding of the first fixing knot can fix the first end of the first filament. The second end of the first filament is extended to the distal or proximal end and woven around the axis of the support at a position adjacent to the axial direction of the middle wave loop of the first section. The second end of the first filament completes at least one lap of weaving to form the middle wave loop of the second section, wherein the middle wave loop of the second section is axially adjacent to the middle wave loop of the first section. Continue to extend the second end of the first filament towards the far end or near end, and weave it sequentially according to the weaving method of the middle wave loop of the second section until the last middle wave loop is formed; After the last section of the middle wave loop is completed, the second end of the first filament is wound around any one of the middle wave loops to form a V-shaped second fixed knot. The first end of the second filament is wound and fixed on any one of the middle wave loops to form a V-shaped third fixing knot. The second end of the second filament is extended proximally and then woven around the axis of the support. The second end of the second filament completes at least one weave to form the proximal wave loop, which is adjacent to and located proximal to the first middle wave loop. The second end of the second filament is then wound and fixed on any one of the middle wave loops to form a V-shaped fourth fixing knot. At least one of the first fixing knot, the second fixing knot, the third fixing knot, and the fourth fixing knot is wrapped with PTFE thread or PTFE film.

2. The method for preparing the stent as described in claim 1, characterized in that, The preparation method further includes: The first end of the third filament is wound and fixed on any one of the middle wave loops to form a fifth fixing knot. The second end of the third filament is extended distally and then woven around the axis of the support. The second end of the third filament completes at least one weave to form the distal wave loop, which is adjacent to and located distal to the last middle wave loop. The second end of the third filament is then wound and fixed on any one of the middle wave loops to form a sixth fixing knot. The middle waveband is located between the near-end waveband and the far-end waveband.

3. The method for preparing the stent as described in claim 1, characterized in that, The central waveband has multiple first filaments with different diameters, and the first end and the second end of each first filament are fixed to any one of the central wavebands.

4. The method for preparing the stent as described in claim 2, characterized in that, At least one of the fifth and sixth fixing knots is wrapped with thread or film or covered with a connector.

5. The method for preparing the stent as described in claim 4, characterized in that, The line or the film is reproducible.

6. The method for preparing the stent as described in claim 4, characterized in that, The connector includes a first component and a second component, which are fixedly connected. A first end of the first filament, a second end of the first filament, a first end of the second filament, a second end of the second filament, a first end of the third filament, or a second end of the third filament are disposed between the first component and the second component.

7. The method for preparing the stent as described in claim 4, characterized in that, The maximum width of the connector in the axial direction is 1.5 to 3 times the diameter of the first wire, the second wire, or the third wire.

8. The method for preparing the stent as described in claim 6, characterized in that, The first component includes a first protrusion and a first groove, and the second component further includes a second protrusion and a second groove. The first protrusion and the second groove are connected to each other, and the second protrusion and the first groove are connected to each other; or, the first component and the second component are connected by welding.

9. The method for preparing the stent as described in claim 4, characterized in that, The material of the connector includes a radiopaque metallic material.

10. The method for preparing the stent as described in claim 4, characterized in that, The connector has a smooth outer surface.

11. A method for fabricating a stent, the stent comprising a middle waveguide, a distal waveguide, and a proximal waveguide, characterized in that, Includes the following steps: The first end of the first filament is fixed, and the second end of the first filament is woven around the axis of the bracket. The second end of the first filament completes at least one loop of weaving to form the first section of the middle wave loop. The second end of the first filament returns to the starting point and is wound around the first section of the middle wave loop to form a V-shaped first fixing knot. The winding of the first fixing knot can fix the first end of the first filament. The second end of the first filament is extended to the distal or proximal end and woven around the axis of the support at a position adjacent to the axial direction of the middle wave loop of the first section. The second end of the first filament completes at least one lap of weaving to form the middle wave loop of the second section, wherein the middle wave loop of the second section is axially adjacent to the middle wave loop of the first section. Continue to extend the second end of the first filament towards the far end or near end, and weave it sequentially according to the weaving method of the middle wave loop of the second section until the last middle wave loop is formed; After the last section of the middle wave loop is completed, the second end of the first filament is wound around any one of the middle wave loops to form a V-shaped second fixed knot. The first end of the second filament is wound and fixed on any one of the middle wave loops to form a V-shaped third fixing knot. The second end of the second filament is extended distally and then woven around the axis of the support. The second end of the second filament completes at least one loop of weaving to form the distal wave loop, wherein the distal wave loop is adjacent to and located distal to the middle wave loop of the first section. The second end of the second filament is then wound and fixed on any one of the middle wave loops to form a V-shaped fourth fixing knot. At least one of the first fixing knot, the second fixing knot, the third fixing knot, and the fourth fixing knot is wrapped with PTFE thread or PTFE film.

12. The method for preparing the stent as described in claim 11, characterized in that, The preparation method further includes: The first end of the third filament is wound and fixed on any one of the middle wave loops to form a fifth fixing knot. The second end of the third filament is extended proximally and then woven around the axis of the support. The second end of the third filament completes at least one weave to form the proximal wave loop, which is adjacent to and located proximal to the last middle wave loop. The second end of the third filament is then wound and fixed on any one of the middle wave loops to form a sixth fixing knot. The middle waveband is located between the near-end waveband and the far-end waveband.

13. The method for preparing the stent as described in claim 11, characterized in that, The central waveband has multiple first filaments with different diameters, and the first end and the second end of each first filament are fixed to any one of the central wavebands.

14. The method for preparing the stent as described in claim 12, characterized in that, At least one of the fifth and sixth fixing knots is wrapped with thread or film or covered with a connector.

15. The method for preparing the stent as described in claim 14, characterized in that, The line or the film is reproducible.

16. The method for preparing a stent as described in claim 14, characterized in that, The connector includes a first component and a second component, which are fixedly connected. A first end of the first filament, a second end of the first filament, a first end of the second filament, a second end of the second filament, a first end of the third filament, or a second end of the third filament are disposed between the first component and the second component.

17. The method for preparing a stent as described in claim 14, characterized in that, The maximum width of the connector in the axial direction is 1.5 to 3 times the diameter of the first wire, the second wire, or the third wire.

18. The method for preparing a stent as described in claim 16, characterized in that, The first component includes a first protrusion and a first groove, and the second component further includes a second protrusion and a second groove. The first protrusion and the second groove are connected to each other, and the second protrusion and the first groove are connected to each other; or, the first component and the second component are connected by welding.

19. The method for preparing the stent as described in claim 14, characterized in that, The material of the connector includes a radiopaque metallic material.

20. The method for preparing the stent as described in claim 14, characterized in that, The connector has a smooth outer surface.

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