Blood purification equipment blood return control method, blood purification equipment and computer-readable storage medium

Abstract

This invention provides a blood return control method for a blood purification device, the blood purification device itself, and a computer-readable storage medium. The blood return control method includes: controlling the blood purification device to enter the blood return phase; detecting the cumulative decrease Q of the backflushing fluid in the reservoir bag; determining whether the cumulative decrease Q is greater than a preset safety amount ΔQ1; if so, detecting the color of the fluid in the venous tubing; and determining whether the color of the fluid in the venous tubing is red; if not, controlling the blood purification device to stop connecting the reservoir bag to complete the blood return phase. This invention's blood return control method can dually determine whether the blood purification device has achieved sufficient blood return during the blood return phase based on both the cumulative decrease of the backflushing fluid in the reservoir bag and the color of the fluid in the venous tubing. It can precisely control the blood purification device to perform the blood return phase operation, improving the blood purification treatment effect and making blood purification treatment safer and more reliable.

Description

Technical Field

[0001] This invention relates to the field of control technology for blood purification equipment, and in particular to a blood return control method for blood purification equipment, a blood purification equipment for implementing the blood return control method, and a computer-readable storage medium. Background Technology

[0002] Blood purification equipment is a type of medical device. When used clinically, it involves drawing blood from the patient and placing it in an extracorporeal circulation loop. The blood is then transferred to a blood purifier for further purification, removing specific substances. The purified blood is then returned to the patient, completing the purification process and achieving the goal of treating the disease. Different blood purification treatment modes are possible, such as hemodialysis, hemofiltration, hemodiafiltration, hemoperfusion, plasma exchange, and immunoadsorption. Each mode has specific clinical treatment symptoms, and long-term clinical practice has proven that blood purification treatments using these devices achieve good clinical outcomes.

[0003] When blood purification equipment is used clinically, the control process can be divided into the following steps: power-on, self-test, pre-priming, purification treatment, blood return, and power-off. After the blood purification equipment has purified the patient's blood, a blood return procedure is required. Specifically, the blood return procedure involves returning all residual blood from the extracorporeal circulation tubing and the blood purifier to the patient's body to prevent blood waste during the purification treatment.

[0004] However, current methods for controlling blood return in blood purification equipment rely on medical staff manually setting the return time and volume based on their experience. This can easily lead to operational errors during the return phase. For example, if the return volume is too large, too much residual fluid will be injected into the body, affecting the patient's blood purification treatment outcome; if the return volume is too small, insufficient return will result in blood waste and endanger the patient's safety. Therefore, relying on medical staff to manually set the return time and volume based on experience makes it difficult to accurately set the appropriate return volume, resulting in poor return effects from the blood purification equipment. Summary of the Invention

[0005] The primary objective of this invention is to provide a blood return control method for a blood purification device that can make dual judgments based on the cumulative reduction of the backflushing fluid and the color of the fluid in the venous tubing to ensure sufficient blood return during the blood return phase. This method overcomes the problems of excessive or insufficient blood return caused by existing methods that rely on medical staff to manually set the blood return time and amount based on their experience. As a result, the method can precisely control the blood purification device to perform the blood return phase operation, thereby improving the therapeutic effect of blood purification and making blood purification treatment safer and more reliable.

[0006] A second objective of this invention is to provide a blood purification device that implements the above-described blood return control method.

[0007] A third objective of this invention is to provide a computer-readable storage medium for implementing the above-described blood return control method.

[0008] To achieve the first objective of this invention, the present invention provides a blood return control method for a blood purification device. The extracorporeal circulation circuit of the blood purification device includes a reservoir bag, an arterial line, a blood purifier, and a venous line. The input end of the arterial line is connected to an artery in the human body, the output end of the arterial line is connected to the input end of the blood purifier, the output end of the blood purifier is connected to the input end of the venous line, and the output end of the venous line is connected to a vein in the human body. The venous line is equipped with a blood detector for detecting the color of the liquid. The reservoir bag can be connected to one of the input ends of the arterial line, the blood purifier, and the venous line. The reservoir bag contains... The blood purification device, which stores backfill fluid, employs a blood return control method comprising: when the continuous purification time of the blood purifier is greater than or equal to a preset purification time, controlling the connection between the fluid reservoir and one of the following: the input end of the arterial line, the input end of the blood purifier, or the input end of the venous line, so that the blood purification device enters the blood return phase operation; detecting the cumulative decrease Q of the backfill fluid in the fluid reservoir; determining whether the cumulative decrease Q is greater than a preset safety amount ΔQ1; if so, detecting the color of the fluid in the venous line; and determining whether the color of the fluid in the venous line is red; if not, controlling the blood purification device to stop connecting the fluid reservoir to complete the blood return phase operation.

[0009] As can be seen from the above scheme, the blood return control method of the blood purification device of the present invention can make a dual judgment based on the cumulative reduction Q of the backflow fluid in the reservoir bag and the color of the fluid in the venous tubing to ensure that the blood purification device has achieved sufficient blood return during the blood return stage. This overcomes the problem of excessive or insufficient blood return caused by relying on medical staff to manually set the blood return time and amount based on experience. Thus, it can accurately control the blood purification device to perform the blood return stage operation, thereby improving the blood purification treatment effect and making the blood purification treatment safer and more reliable.

[0010] A preferred embodiment is that when the reservoir bag is connected to the input end of the arterial tubing for the blood return phase operation, the blood return control method of the blood purification device further includes: detecting the first detection flow rate Q1 of the return fluid entering the arterial tubing, and obtaining a preset safety amount ΔQ1 based on the first detection flow rate Q1, wherein the preset safety amount ΔQ1 is positively correlated with the first detection flow rate Q1; or, detecting the first detection flow rate Q1 of the return fluid entering the arterial tubing, and controlling the first detection flow rate Q1 to decrease according to a preset decreasing rule.

[0011] A further proposed solution is that the blood return control method for the blood purification device also includes: when the continuous purification time of the blood purifier is less than a preset purification time, detecting the blood flow in the artery connected to the human body through the arterial tubing to obtain a second detection flow rate Q2; and calculating and obtaining a preset constant flow rate. When the continuous purification time of the blood purifier is greater than or equal to the preset purification time, and when the reservoir bag is connected to the input end of the arterial line for the blood return stage operation, the arterial line is controlled to receive the return fluid at a preset constant flow rate ΔQ2.

[0012] A further proposed solution involves the following steps for controlling the blood return in the blood purification device: when the color of the fluid in the venous tubing is determined to be red, the blood purification device is controlled to issue a blood return fault alarm signal and the fluid flow rate in the venous tubing is detected to obtain a third detection flow rate Q3; it is then determined whether the third detection flow rate Q3 is less than a preset minimum flow rate; if so, the blood purification device is controlled to issue a venous tubing blockage fault signal; if not, the blood return calibration amount ΔQ3 of the blood purification device is obtained based on the RGB value of the color of the fluid in the venous tubing, and then it is determined whether Q>ΔQ1+ΔQ3 is satisfied; if so, the blood purification device is controlled to stop connecting the reservoir bag to complete the blood return stage operation; wherein, the blood return calibration amount ΔQ3 is positively correlated with the RGB value of the color of the fluid in the venous tubing.

[0013] A further proposed solution is to have the inner diameter of the arterial tubing equal to that of the venous tubing. The blood return control method of the blood purification device also includes: detecting the length L1 of the arterial tubing and the length L2 of the venous tubing; when L1>L2, determining whether the cumulative reduction Q is less than the blood volume q1 of the arterial tubing; if so, controlling the connection between the reservoir bag and the input end of the arterial tubing; if not, controlling the connection between the reservoir bag and the input end of the blood purifier.

[0014] A further solution is that the blood return control method of the blood purification device further includes: when Q≤q1, controlling the connection between the liquid storage bag and the input end of the arterial pipeline, and controlling the arterial pipeline to access the backflush liquid at a first preset liquid flow rate, where q1 is the blood volume of the arterial pipeline; when q1<Q≤q1+q2, controlling the connection between the liquid storage bag and the input end of the blood purifier, and controlling the blood purifier to access the backflush liquid at a second preset liquid flow rate, and controlling the multifunctional hammer to strike the input end or the output end of the blood purifier at a preset striking frequency, where q2 is the blood volume of the blood purifier; when q1+q2<Q≤ΔQ1, controlling the connection between the liquid storage bag and the input end of the venous pipeline, and controlling the venous pipeline to access the backflush liquid at a third preset liquid flow rate; wherein, the first preset liquid flow rate is greater than the second preset liquid flow rate, and the second preset liquid flow rate is greater than the third preset liquid flow rate.

[0015] A further solution is that when the liquid storage bag is connected to the input end of the arterial pipeline for the blood return stage operation, the blood return control method of the blood purification device further includes: detecting the temperature of the backflush liquid in the liquid storage bag to obtain the first detected temperature T1, and detecting the liquid temperature in the venous pipeline to obtain the second detected temperature T2; judging whether T2-T?ΔT is satisfied, if so, controlling the blood purification device to send out a backflush liquid temperature fault signal; wherein, ΔT is a preset temperature difference.

[0016] A further solution is that the blood purifier is a plasma separator. An intravenous drip chamber is provided at the input end of the venous line. The blood cell output end of the plasma separator is connected to the first inlet end of the intravenous drip chamber through a first branch. The plasma output end of the plasma separator is connected to the second inlet end of the intravenous drip chamber through a second branch. An adsorption column and a filtration pump are provided on the second branch. A first on-off clamp is provided at a position close to the blood cell output end of the plasma separator on the first branch, and a second on-off clamp is provided at a position close to the plasma output end of the plasma separator on the second branch. The blood purification equipment's blood return control method further includes: calculating and obtaining a first safety volume Δq1 = q1 + q2 + q4 and a second safety volume Δq2 = q5 + q6 + q3, where q1 is the blood volume of the arterial line, q2 is the blood volume of the blood purifier, q3 is the blood volume of the venous line, q4 is the blood volume of the first branch, q5 is the blood volume of the second branch, and q6 is the blood volume of the intravenous drip chamber; when it is determined that Q ≤ Δq1, then control the liquid storage bag to be connected to the input end of the arterial line, control the arterial line to access the backflush liquid at a first preset flow rate, and control the first on-off clamp to open and the second on-off clamp to close; when it is determined that Δq1 < q ≤ Δq1 + Δq2, then control the liquid storage bag to be connected to the input end of the arterial line, control the arterial line to access the backflush liquid at a second preset flow rate, and control the second on-off clamp to open and the first on-off clamp to close, and detect the liquid temperature of the venous line to obtain a second detection temperature T2. When it is determined that the second detection temperature T2 is less than the preset safety temperature, then control the blood purification equipment to send out a temperature prompt message, where the first preset flow rate is greater than the second preset flow rate; when it is determined that q > Δq1 + Δq2, then determine whether the color of the liquid in the venous line is red.

[0017] To achieve the second object of the present invention, the present invention provides a blood purification equipment, including a main body and a display screen. A circuit board capable of realizing interactive communication with the display screen is provided inside the main body. A processor and a memory are provided on the circuit board. The memory stores a computer program. When the computer program is executed by the processor, each step of the above-mentioned blood return control method of the blood purification equipment is realized.

[0018] To achieve the third object of the present invention, the present invention provides a computer-readable storage medium, on which a computer program is stored. When the computer program is executed by the processor, each step of the above-mentioned blood return control method of the blood purification equipment is realized. BRIEF DESCRIPTION OF THE DRAWINGS

[0019] Figure 1 It is a structural diagram of an embodiment of the blood purification equipment of the present invention.

[0020] Figure 2 It is a working principle diagram of an embodiment of the blood purification equipment of the present invention.

[0021] Figure 3This is a flowchart of an embodiment of the blood return control method of the blood purification device of the present invention.

[0022] Figure 4 This is a graph showing the relationship between the preset safety amount and the flow rate of the backflush fluid connected to the arterial pipeline in an embodiment of the blood purification device backflush control method of the present invention.

[0023] Figure 5 This is a schematic diagram of a multi-functional hammer striking a blood purifier in an embodiment of the blood purification device's blood return control method of the present invention.

[0024] Figure 6 This is a schematic diagram illustrating the working principle of a plasma separator as the blood purifier in an embodiment of the blood purification equipment of the present invention.

[0025] The present invention will be further described below with reference to the accompanying drawings and embodiments. Detailed Implementation

[0026] Example of blood return control method for blood purification equipment:

[0027] The blood return control method of the blood purification device in this embodiment is applied to the blood purification device. See [link to relevant documentation]. Figure 1 The blood purification device includes a main unit 1 and a display screen 2, which is a human-computer interactive touch screen. The main unit 1 is equipped with a circuit board that can interact and communicate with the display screen 2. The circuit board is equipped with a processor and a memory. The memory stores a computer program. When the computer program is executed by the processor, it implements the various steps of the blood return control method of the blood purification device in this embodiment. Thus, the display screen 2 and the main unit 1 can interact and communicate. Medical staff can input instructions on the display screen 2 so that the blood purification device can execute the various steps of the blood return control method of the blood purification device in this embodiment according to the operation requirements of the medical staff, so as to ensure the safety of the patient's blood purification treatment.

[0028] See Figure 2The extracorporeal circulation circuit of the blood purification device includes a reservoir bag, arterial clamp 31, blood pump 32, heparin pump 33 (i.e., anticoagulant pump), blood purifier 34, venous reservoir 36, liquid level detector 35, air bubble detector 37, blood detector 38, venous clamp 39, arterial line 310, and venous line 311. The input end of arterial line 310 is used to connect to the artery of the human body, and the output end of arterial line 310 is connected to the input end of blood purifier 34. The output end of blood purifier 34 is connected to the input end of venous line 311 through venous reservoir 36. The output end of venous line 311 is used to connect to the vein of the human body. Blood detector 38 is used to detect the color of the liquid in venous line 311. Arterial line 310 delivers blood from the body to blood purifier 34, driven by blood pump 32, causing blood to circulate between arterial line 310 and venous line 311. As blood passes through blood purifier 34, it filters out specific molecules in the blood, purifying it before returning the purified blood to the body via venous line 311, thus purifying the blood and treating diseases. Specifically, in this embodiment, a reservoir bag can be connected to one of the input ends of arterial line 310, blood purifier 34, or venous line 311. The reservoir bag stores backfill fluid. It should be noted that the input end of arterial line 310 is connected to the body's artery only when the blood purification device is in the blood purification stage. During the backfill stage, the input end of arterial line 310 is not connected to the body's artery, but can be connected to the reservoir bag.

[0029] In this embodiment, the blood purification device can realize multiple blood purification treatment modes, such as hemodialysis, hemofiltration, hemodiafiltration, hemoperfusion, plasma exchange, and immunoadsorption. When the blood purification device is in different blood purification treatment modes, the type of blood purifier 34 will be different. For example, in the hemoperfusion treatment mode, the blood purifier 34 is a hemoperfusion device; in the hemodialysis treatment mode, the blood purifier 34 is a dialyzer. When the blood purification device is in different blood purification treatment modes, the components of the extracorporeal circulation circuit of the blood purification device will also change. Figure 2 This diagram illustrates the most basic structure of the extracorporeal circulation circuit of a blood purification device. When the blood purification device is in different blood purification treatment modes, the extracorporeal circulation circuit will... Figure 2 Improvements or modifications are made based on this.

[0030] See Figure 3 , Figure 3 This is a flowchart of the blood return control method of the blood purification device in this embodiment. The specific execution steps of the blood return control method of the blood purification device in this embodiment are as follows.

[0031] Step S1: Determine if the blood purification device is in the blood purification stage before proceeding to step S2.

[0032] Specifically, the working process of the blood purification equipment includes at least the following stages: pre-flushing, blood intake, blood purification, and blood return. In the pre-flushing stage, the arterial line 310, blood purifier 34, and venous line 311 are sequentially flushed with pre-flushing fluid to remove impurities and gases from these components. In the blood intake stage, the patient's blood is drawn into the arterial line 310. In the blood purification stage, the blood purifier 34 performs normal blood purification on the patient's blood. In the blood return stage, when the patient's blood purification treatment is about to end, the residual blood in the arterial line 310, blood purifier 34, and venous line 311 is returned to the patient.

[0033] Step S2: Determine whether the continuous purification time of the blood purifier 34 is less than the preset purification time. If yes, proceed to step S3; otherwise, proceed to step S5.

[0034] Step S3: When step S2 determines that the continuous purification time of the blood purifier 34 is less than the preset purification time, step S3 determines whether the continuous purification time of the blood purifier 34 is less than the preset safe time. If yes, then step S1 is executed, and the blood purification device continues to perform blood purification operation; if no, then step S4 is executed.

[0035] Step S4: When step S3 determines that the continuous purification time of the blood purifier 34 is greater than or equal to the preset safe time, step S4 controls the blood purification device to emit an indicator light to indicate that the blood purification device is about to enter the blood return stage. The preset safe time is less than the preset purification time.

[0036] Specifically, the continuous purification time of the blood purifier 34 represents the continuous time the blood purification device is in the blood purification stage. This continuous purification time is obtained by detecting the time the blood is continuously connected to the input end of the arterial line 310. The preset purification time represents the total blood purification treatment time set by the user, typically based on clinical treatment needs. Usually, the continuous purification time is 12 to 24 hours. Only when the continuous purification time of the blood purifier 34 is less than the preset purification time will a blood return control signal not be issued, allowing the blood purification device to operate safely in the blood purification stage. When the continuous purification time of the blood purifier 34 is greater than or equal to the preset purification time, a blood return control signal is issued. This signal connects the reservoir bag to one of the input ends of the arterial line 310, the blood purifier 34, or the venous line 311, allowing the blood purification device to enter the blood return stage operation, i.e., proceeding to step S5, to ensure the normal operation of the blood purification device.

[0037] A preset safety time can identify whether the blood purification device is about to enter the blood return phase. The preset safety time is less than the preset purification time, for example, a preset safety time of 1195 minutes and a preset purification time of 1200 minutes. When the continuous purification time of the blood purifier 34 is greater than or equal to 1195 minutes and less than 1200 minutes, the blood purification device emits an indicator light. This indicator light alerts the user that the blood purification device is about to enter the blood return phase. Upon seeing the indicator light, the user can prepare in advance for the blood return phase, facilitating the switch from the blood purification phase to the blood return phase and ensuring the safety of the blood purification device's control. This embodiment's blood return control method controls the blood purification device to emit an indicator light to indicate that it is about to enter the blood return phase, making the blood purification device more easy to control.

[0038] It should be noted that a preset safety time is set in advance based on clinical treatment experience. Usually, the preset safety time is 5 minutes less than the preset purification time. For example, if the preset purification time is 1000 minutes, the preset safety time is 995 minutes.

[0039] Step S5: When step S2 determines that the continuous purification time of the blood purifier 34 is greater than or equal to the preset purification time, step S5 controls the connection between the reservoir bag and one of the input ends of the arterial line 310, the blood purifier 34, and the venous line 311, so that the blood purification device enters the blood return phase operation, that is, step S5 controls the blood purification device to enter the blood return phase.

[0040] When the reservoir bag is connected to the input end of the arterial line 310, the backflushing fluid in the reservoir bag sequentially flushes the arterial line 310, the blood purifier 34, and the venous line 311, flushing away all residual blood in the arterial line 310, the blood purifier 34, and the venous line 311, thus achieving blood return. When the reservoir bag is connected to the input end of the blood purifier 34, the backflushing fluid in the reservoir bag sequentially flushes the blood purifier 34 and the venous line 311, flushing away all residual blood in the blood purifier 34 and the venous line 311, thus achieving blood return. When the reservoir bag is connected to the input end of the venous line 311, the backflushing fluid in the reservoir bag directly flushes the venous line 311, flushing away all residual blood in the venous line 311, thus achieving blood return.

[0041] The reservoir bag pre-stores a certain volume of flushing fluid, such as 2L of flushing fluid, which can be water for injection.

[0042] Step S6, detect the cumulative reduction amount Q of the backflush fluid in the liquid storage bag. Specifically, when the liquid storage bag is connected to one of the input ends of the arterial pipeline 310, the input end of the blood purifier 34, and the input end of the venous pipeline 311, the volume of the backflush fluid in the liquid storage bag will gradually decrease. Then, the cumulative reduction amount Q of the backflush fluid in the liquid storage bag represents the volume of the backflush fluid connected to the blood purification device. For example, if the cumulative reduction amount Q of the backflush fluid in the liquid storage bag is 300 ml, this means that the blood purification device has connected 300 ml of backflush fluid.

[0043] Step S7, determine whether the cumulative reduction amount Q is greater than the preset safety amount ΔQ1. If so, execute step S14; if not, execute step S8.

[0044] Step S8, when it is determined in step S7 that the cumulative reduction amount Q is less than or equal to the preset safety amount ΔQ1, step S8 determines whether Q≤q1 is satisfied. If so, execute step S9; if not, execute step S10. Here, q1 is the blood volume of the arterial pipeline 310.

[0045] Specifically, the preset safety amount ΔQ1 represents the safe amount of backflush fluid used by the blood purification device during the blood return stage. The preset safety amount ΔQ1 is determined by the pipeline structure of the blood purification device. When the blood purification device realizes different blood purification treatment modes, the pipeline structure of the blood purification device is different. Generally, the more complex the pipeline structure of the blood purification device, the larger the preset safety amount ΔQ1. For example, for the pipeline structure in the hemoperfusion treatment mode, the preset safety amount ΔQ1 is usually 600 ml. When the cumulative reduction amount Q of the backflush fluid in the liquid storage bag is greater than 600 ml, it means that the volume of the backflush fluid connected to the blood purification device has exceeded the safe amount during the blood return stage. At this time, it is also necessary to detect the color of the liquid in the venous pipeline 311 to determine whether the blood purification device has fully returned blood.

[0046] Step S9, when it is determined in step S8 that Q≤q1 is satisfied, step S9 controls the liquid storage bag to be connected to the input end of the arterial pipeline 310, and controls the arterial pipeline 310 to access the backflush fluid at the first preset liquid flow rate. Then, execute step S6 to detect the cumulative reduction amount Q of the backflush fluid in the liquid storage bag in real time.

[0047] Step S10, when it is determined in step S8 that Q≤q1 is not satisfied, step S10 determines whether q1<Q≤q1 + q2 is satisfied. If so, execute step S11; if not, execute step S12. Here, q2 is the blood volume of the blood purifier 34. [[ID=十八]]

[0048] Step S11, when it is judged in step S10 that q1 < Q ≤ q1 + q2, then step S11 controls the liquid storage bag to be connected to the input end of the blood purifier 34, and controls the blood purifier 34 to access the backflush liquid at the second preset liquid flow rate, and then executes step S6 to detect the cumulative reduction amount Q of the backflush liquid in the liquid storage bag in real time.

[0049] Step S12, when it is judged in step S10 that q1 < Q ≤ q1 + q2 is not satisfied, then step S12 judges whether q1 + q2 < Q ≤ ΔQ1 is satisfied. If so, step S13 is executed; if not, step S6 is executed to detect the cumulative reduction amount Q of the backflush liquid in the liquid storage bag in real time.

[0050] Step S13, when it is judged in step S12 that q1 + q2 < Q ≤ ΔQ1 is satisfied, then step S13 controls the liquid storage bag to be connected to the input end of the venous line 311, and controls the venous line 311 to access the backflush liquid at the third preset liquid flow rate, and then executes step S6 to detect the cumulative reduction amount Q of the backflush liquid in the liquid storage bag in real time.

[0051] Among them, the first preset liquid flow rate is greater than the second preset liquid flow rate, and the second preset liquid flow rate is greater than the third preset liquid flow rate.

[0052] Specifically, before entering the blood return stage, the blood volume q1 of the arterial line 310, the blood volume q2 of the blood purifier 34, and the blood volume q3 of the venous line 311 are detected, and the total volume q of the blood purification device is calculated as q = q1 + q2 + q3. The blood volume q1 of the arterial line 310 represents the maximum volume of liquid that the arterial line 310 can hold. The blood volume q3 of the venous line 311 represents the maximum volume of liquid that the venous line 311 can hold. The blood volume q2 of the blood purifier 34 represents the maximum volume of liquid that the blood purifier 34 can hold. It should be noted that there are biochemical materials such as adsorbents and hollow fiber membranes inside the blood purifier 34. Therefore, the maximum volume of liquid that the blood purifier 34 can hold refers to the maximum volume of liquid that the blood purifier 34 can hold after storing biochemical materials inside. For example, the volume of the biochemical materials stored inside the blood purifier 34 is 500 ml (the biochemical materials are stored in the form of a solution), and the maximum volume of liquid that the blood purifier 34 can hold is 300 ml. Therefore, the blood volume q2 of the blood purifier 34 is 300 ml. The total volume q of the blood purification device represents the maximum volume of liquid that the blood purification device can store. In the blood purification stage, the total volume q represents the maximum volume of blood that the blood purification device can store. For example, the total volume q is 1000 ml.

[0053] This embodiment divides the blood return stage of the blood purification device into the first process, the second process, and the third process in sequence, which are as follows:

[0054] In the first process, when Q ≤ q1 is satisfied, the liquid storage bag is controlled to be connected to the input end of the arterial pipeline 310, and the arterial pipeline 310 is controlled to access the backflush liquid at a first preset liquid flow rate. At this time, the backflush liquid enters the arterial pipeline 310 at the first preset liquid flow rate for flushing, and all the residual blood in the arterial pipeline 310, the residual blood in the blood purifier 34, and the residual blood in the venous pipeline 311 are flushed into the human vein by the backflush liquid, so as to realize the blood return operation in the first process, and the arterial pipeline 310 is mainly flushed;

[0055] In the second process, when q1 < Q ≤ q1 + q2 is satisfied, the liquid storage bag is controlled to be connected to the input end of the blood purifier 34, and the blood purifier 34 is controlled to access the backflush liquid at a second preset liquid flow rate. At this time, the backflush liquid enters the blood purifier 34 at the second preset liquid flow rate for flushing, and all the residual blood in the blood purifier 34 and the residual blood in the venous pipeline 311 are flushed into the human vein by the backflush liquid, so as to realize the blood return operation in the second process, and the blood purifier 34 is mainly flushed;

[0056] In the third process, when q1 + q2 < Q ≤ ΔQ1 is satisfied, the liquid storage bag is controlled to be connected to the input end of the venous pipeline 311, and the venous pipeline 311 is controlled to access the backflush liquid at a third preset liquid flow rate. At this time, the backflush liquid enters the venous pipeline 311 at the third preset liquid flow rate for flushing, and all the residual blood in the venous pipeline 311 is flushed into the human vein by the backflush liquid, so as to realize the blood return operation in the third process, and only the venous pipeline 311 is flushed.

[0057] In each of the above processes of the blood return control method of the blood purification device in this embodiment, the blood return operation is separately performed on each component of the extracorporeal circulation loop of the blood purification device. In this way, not only the problem of insufficient blood return is avoided, but also the components can be efficiently backflushed by the backflush liquid, and the blood purification device can achieve efficient and sufficient blood return.

[0058] It should be noted that in the blood return control method of the blood purification device in this embodiment, the first preset liquid flow rate is greater than the second preset liquid flow rate, and the second preset liquid flow rate is greater than the third preset liquid flow rate, which can ensure that as the flow rate of the backflush liquid gradually decreases during the blood return stage, the backflush liquid can achieve the best blood return effect on the components in the later stage. Generally, the flushing difficulty of the venous pipeline 311 is the greatest, and the flushing difficulty of the arterial pipeline 310 is the smallest. Therefore, the third preset liquid flow rate is the smallest, and the backflush liquid can achieve the best blood return effect on the venous pipeline 311 at the third preset liquid flow rate.

[0059] Step S14, when it is judged in step S7 that the cumulative reduction amount Q of the backflush liquid in the liquid storage bag is greater than the preset safety amount ΔQ1, then step S14 detects the color of the liquid in the venous pipeline 311.

[0060] Step S15: Determine if the color of the liquid in the intravenous tubing 311 is red. If yes, proceed to step S16; otherwise, proceed to step S21: Control the blood purification device to stop connecting the storage bag to complete the blood return stage operation.

[0061] In step S16, when step S15 determines that the color of the liquid in the venous tubing 311 is red, step S16 controls the blood purification device to issue a blood return fault alarm signal and detects the liquid flow rate of the venous tubing 311 to obtain the third detection flow rate Q3.

[0062] Step S17: Determine whether the third detection flow Q3 is less than the preset minimum flow. If yes, proceed to step S18; otherwise, proceed to step S19.

[0063] Step S18: When step S17 determines that the third detection flow rate Q3 is less than the preset minimum flow rate, step S18 controls the blood purification device to send a blockage fault signal for the venous line 311.

[0064] Specifically, when the color of the liquid in the venous line 311 is detected to be red, it indicates that the blood purification device has not fully returned blood and there is still some blood remaining in the venous line 311. The blood purification device can send an audible and visual alarm to the user through the blood return fault alarm signal. Once the user receives the blood return fault alarm signal, he / she will know that the blood purification device has a blood return fault.

[0065] The blood return control method of the blood purification device in this embodiment determines whether the venous line 311 is blocked based on the flow rate of the fluid in the venous line 311. Specifically, it compares the third detected flow rate Q3 of the fluid in the venous line 311 with a preset minimum flow rate (typically, the preset minimum flow rate is 1 ml / min) to determine whether the venous line 311 is blocked. A blockage is only determined when the third detected flow rate Q3 of the fluid in the venous line 311 is less than the preset minimum flow rate.

[0066] It should be noted that when the cumulative decrease in backflushing fluid Q exceeds the preset safety amount ΔQ1, the venous line 311 may not be properly flushed, and this malfunction is usually caused by a blockage in the venous line 311. Therefore, in step S17, by determining whether the third detection flow rate Q3 of the fluid in the venous line 311 is less than the preset minimum flow rate, it is possible to determine whether the venous line 311 is blocked, thereby identifying the specific reason why the blood purification equipment has not returned sufficient blood.

[0067] Step S19: When step S17 determines that the third detection flow rate Q3 is greater than or equal to the preset minimum flow rate, step S19 obtains the blood return calibration amount ΔQ3 of the blood purification device based on the RGB value of the liquid color in the venous tubing 311.

[0068] Step S20: Determine whether Q > ΔQ1 + ΔQ3 is satisfied. If yes, proceed to step S21; otherwise, proceed to step S19, obtaining the blood return calibration amount ΔQ3 of the blood purification device in real time based on the RGB color value of the liquid in the intravenous line 311. The blood return calibration amount ΔQ3 is positively correlated with the RGB color value of the liquid in the intravenous line 311.

[0069] Step S21: Control the blood purification equipment to stop connecting the storage bag to complete the blood return stage operation.

[0070] Specifically, the backflushing fluid in the reservoir bag is usually colorless or white, while human blood is red. When blood is returned to the arterial line 310, blood purifier 34, and venous line 311 through the backflushing fluid, if the fluid in the venous line 311 is red, it indicates that there is still blood remaining in the venous line 311, and the blood purification device has not fully returned blood. If the fluid in the venous line 311 is not red, it indicates that only backflushing fluid exists in the venous line 311, and all the residual blood in the venous line 311 has been returned to the human body, and the blood purification device has fully returned blood. Therefore, when the blood purification device's blood return control method in this embodiment detects that the fluid in the venous line 311 is not red, it indicates that the blood purification device has fully returned blood, and the device is controlled to stop connecting the reservoir bag to complete the blood return phase operation.

[0071] The blood detector 38 installed on the intravenous line 311 uses the principle of light sensing to determine whether the color of the fluid in the intravenous line 311 is red. The blood detector 38 can detect the color of the fluid in the intravenous line 311 and convert it into RGB values. Based on the RGB values, it quantitatively determines whether the color of the fluid in the intravenous line 311 is red. The RGB values ​​include three color channels: R represents red, G represents green, and B represents blue. Based on the RGB values, the intensity of the color can be quantitatively determined. For example, if the RGB values ​​are (200, 10, 30), then the intravenous line 311 is not blocked. If it is determined that the intravenous line 311 is not sufficiently flushed, it means that the reason for insufficient blood return is that the preset safety volume ΔQ1 is not set properly, or the flow rate of the flushing fluid is not set properly. In this case, it is necessary to continue flushing the intravenous line 311 with flushing fluid to ensure sufficient blood return. Therefore, when the cumulative decrease of the backflushing fluid Q is greater than the preset safety amount ΔQ1, the blood purification equipment will continue to be flushed with the backflushing fluid until Q>ΔQ1+ΔQ3 is met, at which point the blood purification equipment will be controlled to stop connecting the storage bag to complete the blood return stage operation.

[0072] It should be noted that there is a one-to-one correspondence between the RGB values ​​of the liquid color in the venous line 311 and the blood return calibration amount ΔQ3. When the RGB values ​​of the liquid color in the venous line 311 indicate that the darker the liquid color, the higher the degree of blood residue in the venous line 311, the larger the blood return calibration amount ΔQ3, and the longer the blood return time of the venous line 311.

[0073] Therefore, the blood return control method of the blood purification device in this embodiment can make a dual judgment based on the cumulative reduction Q of the backflushing fluid in the reservoir bag and the color of the liquid in the intravenous line 311 to ensure that the blood purification device has achieved sufficient blood return during the blood return stage. This overcomes the problem of excessive or insufficient blood return caused by relying on medical staff to manually set the blood return time and amount based on experience. As a result, it can accurately control the blood purification device to perform the blood return stage operation, thereby improving the blood purification treatment effect and making the blood purification treatment safer and more reliable.

[0074] During the blood return phase, the flow rate of the backflushing fluid has a certain impact on the blood return effect of the arterial line 310, the blood purifier 34, and the venous line 311. Clinical practice shows that the lower the flow rate of the backflushing fluid, the slower the flow rate of the backflushing fluid in the arterial line 310, the venous line 311, and the blood purifier 34, and the longer the time the backflushing fluid remains in the lines. This results in a better flushing effect on residual blood in the arterial line 310, the venous line 311, and the blood purifier 34. In this embodiment, the blood return control method of the blood purification device can calibrate the total capacity q of the blood purification device based on the flow rate of the backflushing fluid connected to the input end of the arterial line 310. The calibrated total capacity q is the preset safety amount ΔQ1. Furthermore, in this embodiment, the blood return control method of the blood purification device can obtain the preset safety amount ΔQ1 based on the first detected flow rate Q1, i.e., execute step S22.

[0075] Step S22: Detect the first flow rate Q1 of the backflushing fluid connected to the arterial tubing 310, and obtain a preset safety level ΔQ1 based on the first flow rate Q1. For example, if the total capacity q of the blood purification device is 300ml, the relationship curve between the preset safety level ΔQ1 and the first flow rate Q1 of the backflushing fluid connected to the arterial tubing 310, obtained after multiple clinical trials by technicians, is shown below. Figure 4 As shown, the smaller the flow rate of the backflushing fluid connected to the arterial line 310, the smaller the preset safety amount ΔQ1 will be. A smaller flow rate of backflushing fluid allows for sufficient blood return to the arterial line 310, venous line 311, and blood purifier 34. Therefore, the blood return control method of the blood purification device in this embodiment is based on the first detected flow rate Q1 of the backflushing fluid connected to the arterial line 310. Figure 4The curve shown provides the corresponding preset safety level ΔQ1. Based on this preset safety level ΔQ1, it is possible to accurately determine whether the blood purification equipment has been adequately recirculated. For example... Figure 4 As shown, the preset safety amount ΔQ1 is usually less than the total capacity q of the blood purification equipment. This is because during the blood purification stage, neither the blood purifier 34 nor the intravenous line 311 is filled with blood. The intravenous line 311 has an intravenous reservoir 36 at its input end. The intravenous reservoir 36 is usually not completely filled with blood. There will be half air and half blood inside the intravenous reservoir 36. Therefore, the preset safety amount ΔQ1 is less than the total capacity q of the blood purification equipment.

[0076] When the inlet of the arterial line 310 is connected to the backflushing fluid, the flow rate of the backflushing fluid connected to the arterial line 310 can be fixed or variable.

[0077] Step S23: When the continuous purification time of the blood purifier 34 is less than the preset purification time, step S23 detects the blood flow of the artery connected to the human body by the arterial tube 310 to obtain the second detection flow rate Q2.

[0078] Step S24: Calculate and obtain the preset constant flow rate.

[0079] Step S25: When the continuous purification time of the blood purifier 34 is greater than or equal to the preset purification time, and when the reservoir bag is connected to the input end of the arterial line 310 for the blood return stage operation, step S25 controls the arterial line 310 to connect to the return fluid at a preset constant flow rate ΔQ2.

[0080] Specifically, the second detection flow rate Q2 refers to the average flow rate of blood in the arterial line 310. During the blood return phase, the flow rate of the backflushing fluid in the arterial line 310 is less than the flow rate of blood in the arterial line 310 during the blood purification phase. This ensures that the backflushing fluid fully pre-flushes the blood purification equipment. Furthermore, during the blood return phase, the flow rate of the backflushing fluid in the arterial line 310 remains constant, i.e., it is always a preset constant flow rate ΔQ2, thereby simplifying the blood return rate control steps of the blood purification equipment.

[0081] In step S26, when the reservoir bag is connected to the input end of the arterial line 310 for the blood return stage operation, step S26 detects the first detection flow rate Q1 of the return fluid connected to the arterial line 310 and controls the first detection flow rate Q1 to decrease according to a preset decreasing rule.

[0082] Specifically, when the reservoir bag is connected to the input end of the arterial line 310 for the blood return phase operation, the first detection flow rate Q1 of the backflushing fluid entering the arterial line 310 will decrease according to the preset decreasing pattern. This is beneficial to exert the blood return effect of the backflushing fluid. Especially in the latter half of the blood return phase, the slowly flowing backflushing fluid can achieve a better blood return effect on the blood purification equipment and fully flush the arterial line 310, the blood purifier 34, and the venous line 311. For example, the preset decreasing pattern can be to decrease the first detection flow rate Q1 of the arterial line 310 into the flushing fluid in the form of a geometric sequence. For example, with a cycle of 30 seconds, the first detection flow rate Q1 of the arterial line 310 into the flushing fluid in the next cycle is 3 / 4 of the first detection flow rate Q1 of the arterial line 310 into the flushing fluid in the previous cycle. The first detection flow rate Q1 of the arterial line 310 into the flushing fluid is gradually decreased according to the preset decreasing pattern to improve the blood return efficiency of the blood purification equipment and to flush the arterial line 310, blood purifier 34, and venous line 311 more thoroughly.

[0083] In one embodiment, the inner diameter of the arterial conduit 310 is equal to the inner diameter of the venous conduit 311. During step S6, when detecting the cumulative decrease Q of the backflushing fluid in the reservoir bag, the following steps are performed.

[0084] Step S27: Detect the length L1 of the arterial conduit 310 and the length L2 of the venous conduit 311.

[0085] In step S28, if L1>L2, then step S28 determines whether the cumulative reduction Q is less than the blood volume q1 of the arterial tube 310. If yes, then step S29 is executed; otherwise, step S30 is executed.

[0086] Step S29: Connect the reservoir bag to the input end of the arterial tubing 310.

[0087] Step S30: Connect the liquid storage bag to the input terminal of the blood purifier 34.

[0088] Specifically, the inner diameter of the arterial conduit 310 is equal to the inner diameter of the venous conduit 311, and the length L1 of the arterial conduit 310 is greater than the length L2 of the venous conduit 311. This indicates that the blood volume q1 of the arterial conduit 310 is greater than the blood volume q3 of the venous conduit 311. When the inlet end of the arterial conduit 310 is connected to the backflushing fluid, the backflushing fluid will flow within the arterial conduit 310 for a relatively long time, and will encounter relatively large resistance forces while flowing within the arterial conduit 310. When the cumulative reduction Q is greater than or equal to the blood volume q1 of the arterial line 310, it indicates that the arterial line 310 has been adequately returned to blood. The reservoir bag is then directly connected to the input end of the blood purifier 34, and the reservoir bag directly outputs the backflushing fluid to the input end of the blood purifier 34. The backflushing fluid continues to return blood to the blood purifier 34 and the venous line 311. The backflushing fluid does not need to flow through the arterial line 310, which is beneficial for flushing the blood purifier 34 and the venous line 311. The flow of the backflushing fluid in the blood purifier 34 and the venous line 311 is smoother, improving the flushing performance of the backflushing fluid.

[0089] It should be noted that the cumulative reduction Q of the backflushing fluid refers to the cumulative amount of backflushing fluid reduction. For example, when the inlet of the arterial line 310 is connected to the reservoir bag, the reduction of backflushing fluid in the reservoir bag is 100ml. When the inlet of the blood purifier 34 is connected to the reservoir bag, the reduction of backflushing fluid in the reservoir bag is 200ml. Therefore, the cumulative reduction Q of backflushing fluid in the reservoir bag is 300ml.

[0090] Therefore, the blood return control method of the blood purification device in this embodiment improves the flushing efficiency of the backflushing fluid on the blood purifier 34 and the venous line 311 by comparing the length L1 of the arterial line 310 and the length L2 of the venous line 311.

[0091] When the reservoir bag is connected to the inlet of the arterial line 310 for the blood return phase operation, the following steps can also be performed.

[0092] Step S31: Detect the temperature of the backfill fluid in the storage bag to obtain a first detection temperature T1, and detect the temperature of the liquid in the intravenous line 311 to obtain a second detection temperature T2.

[0093] Step S32: Determine whether T2-T1>ΔT is satisfied. If yes, proceed to step S33; otherwise, proceed to step S31. Wherein, ΔT is a preset temperature difference value.

[0094] Step S33: Control the blood purification equipment to send a fault signal for the backflushing fluid temperature.

[0095] Specifically, the temperature of the backflushing fluid in the reservoir bag represents the temperature of the backflushing fluid connected to the input end of the arterial line 310, and the fluid temperature in the venous line 311 represents the temperature of the fluid returned to the body through the vein. The temperature of the backflushing fluid during the blood return phase is determined based on the first detection temperature T1 and the second detection temperature T2. For example, if T2-T1>3℃, it indicates that the temperature of the backflushing fluid in the reservoir bag is too low, indicating a temperature malfunction. The low-temperature backflushing fluid mixing with the blood in the tubing results in an excessively low blood temperature during the blood return phase, causing discomfort for the patient.

[0096] The blood return control method of the blood purification device in this embodiment accurately identifies whether the return fluid in the storage bag is in a temperature fault state based on the difference between the first detection temperature T1 and the second detection temperature T2, thereby preventing the temperature of the return fluid from being in a fault state during the blood return stage.

[0097] After the blood purifier 34 is connected to the return fluid at the second preset liquid flow rate, the following steps can also be performed.

[0098] Step S34: Control the multi-functional hammer 4 to strike the input end or the output end of the blood purifier 34 at a preset striking frequency.

[0099] Specifically, see Figure 5 During the blood return phase, the backflushing fluid flows directly into the blood purifier 34. That is, when the blood purification device is in the second stage of the blood return phase, the input end of the blood purifier 34 is directly connected to the backflushing fluid. By tapping the input end or the output end of the blood purifier 34, the impact force generated by the tapping can make the backflushing fluid fill every part of the blood purifier 34, so that the blood hidden in the corners of the blood purifier 34 can also be flushed to the output end of the blood purifier 34, so as to fully return blood to the inside of the blood purifier 34.

[0100] It should be noted that in step S34, the multi-functional hammer 4 strikes the input or output end of the blood purifier 34 at a preset striking frequency. The preset striking frequency can be set according to the specific type and structure of the blood purifier 34. For example, when the blood purifier 34 is a plasma separator, the preset striking frequency is 5 times / minute. Since the amount of residual blood inside the plasma separator is not much, the striking frequency of the multi-functional hammer 4 can be slower. Or, for example, when the blood purifier 34 is a hemoperfusion device, the preset striking frequency is 10 times / minute. Since blood residue is more likely to occur inside the hemoperfusion device, the striking frequency of the multi-functional hammer 4 can be faster so that the backflushing fluid can fill every corner inside the hemoperfusion device, improving the blood return efficiency of the hemoperfusion device.

[0101] See Figure 6 In this embodiment, the blood purifier 34 is a plasma separator 341. A venous reservoir 36 is provided at the input end of the venous line 311. The blood cell output end of the plasma separator 341 is connected to the first inlet end of the venous reservoir 36 through the first branch 312. The plasma output end of the plasma separator 341 is connected to the second inlet end of the venous reservoir 36 through the second branch 313. The second branch 313 is provided with an adsorption column 315, a filtration pump 314, and a heater 316. A first on / off clamp is provided on the first branch 312 near the blood cell output end of the plasma separator 341, and a second on / off clamp is provided on the second branch 313 near the plasma output end of the plasma separator 341. The plasma separator 341 has a plasma separation function. When the arterial line 310 outputs human blood to the plasma separator 341, the plasma separator 341 separates the human blood into blood cells and plasma. The first branch 312 outputs the blood cells to the first inlet of the venous reservoir 36, and the second branch 313 outputs the plasma purified by the adsorption column 315 to the second inlet of the venous reservoir 36. The purified plasma and blood cells are mixed in the venous reservoir 36 to obtain purified blood. The venous line 311 returns the purified blood to the human vein to complete the blood purification treatment. In this embodiment, the blood purifier 34 performs the following steps as the plasma separator 341.

[0102] Step S34: Calculate and obtain the first safety quantity Δq1 = q1 + q2 + q4 and the second safety quantity Δq2 = q5 + q6 + q3, where q1 is the blood volume of the arterial line 310, q2 is the blood volume of the blood purifier 34, q3 is the blood volume of the venous line 311, q4 is the blood volume of the first branch 312, q5 is the blood volume of the second branch 313, and q6 is the blood volume of the venous chamber 36.

[0103] In step S35, when it is determined that Q≤Δq1 is satisfied, step S35 controls the reservoir bag to connect to the input end of the arterial line 310, controls the arterial line 310 to receive the backflushing fluid at the first preset flow rate, and controls the first on / off clamp to open and the second on / off clamp to close.

[0104] Specifically, when the cumulative decrease Q of the backflushing fluid in the reservoir bag is less than or equal to the first safety amount Δq1, the arterial line 310 is controlled to receive the backflushing fluid at the first preset flow rate, and the first on / off clamp is opened and the second on / off clamp is closed. The backflushing fluid will then flow through the arterial line 310, the blood purifier 34, and the first branch 312 to perform the blood return operation. The backflushing fluid will not flow through the second branch 313.

[0105] Step S36: When it is determined that Δq1 < q ≤ Δq1 + Δq2 is satisfied, step S36 controls the liquid storage bag to be connected to the input end of the arterial pipeline 310, controls the arterial pipeline 310 to access the backflush liquid at a second preset flow rate, and controls the second on-off clamp to open and the first on-off clamp to close. Among them, the first preset flow rate is greater than the second preset flow rate.

[0106] Step S37: When it is determined that q > Δq1 + Δq2 is satisfied, step S37 determines whether the color of the liquid in the venous pipeline 311 is red. If so, step S14 is executed to detect the color of the liquid in the venous pipeline 311 in real time; if not, step S21 is executed to control the blood purification device to stop connecting the liquid storage bag to complete the blood return stage operation.

[0107] Specifically, when it is determined that Δq1 < q ≤ Δq1 + Δq2 is satisfied, the arterial pipeline 310 is controlled to access the backflush liquid at a second preset flow rate, and the second on-off clamp is controlled to open and the first on-off clamp to close. Among them, the first preset flow rate is greater than the second preset flow rate, and the backflush liquid will flow through the second branch 313, the venous chamber 36, and the venous pipeline 311 in sequence, so that the second branch 313, the venous chamber 36, and the venous pipeline 311 are filled with the backflush liquid for blood return operation.

[0108] First, blood return operations are performed on the arterial pipeline 310, the blood purifier 34, and the first branch 312, and then blood return control is performed on the plasma in the second branch 313. This sequence can ensure that the blood in the arterial pipeline 310, the venous pipeline 311, the first branch 312, and the second branch 313 can all be fully returned, and can avoid coagulation failures of the blood cells separated by the plasma separator 341 due to untimely blood return, greatly ensuring the blood return safety of the patient.

[0109] When it is determined that Q ≤ Δq1, the arterial pipeline 310 accesses the backflush liquid at a larger first preset flow rate, which can accelerate the blood return rate, and the blood cells in the first branch 312 are not easily attached to the inner wall of the pipeline. Using the backflush liquid with a larger first preset flow rate can flush the first branch 312 clean. The plasma in the second branch 313 is easily attached to the inner wall of the pipeline. Therefore, the flow rate of the backflush liquid in the second branch 313 needs to be as small as possible, and the plasma in the second branch 313 can be completely flushed clean by the backflush liquid with a smaller second preset flow rate. Therefore, the blood return control method of the blood purification device in this embodiment sets the first preset flow rate to be greater than the second preset flow rate, which is beneficial to improving the blood return efficiency of the blood purification device and greatly reducing the blood return control time of the blood purification device.

[0110] Among them, the preset safety volume ΔQ1 = Δq1 + Δq2 in the above steps.

[0111] Step S38: After controlling the arterial pipeline 310 to access the backflush liquid at the second preset flow rate, controlling the second on-off clamp to open and the first on-off clamp to close, step S38 then detects the liquid temperature of the venous pipeline 311 to obtain the second detected temperature T2.

[0112] Step S39: When it is determined that the second detected temperature T2 is lower than the preset safe temperature, step S39 controls the blood purification device to send out a temperature prompt message.

[0113] Specifically, when performing blood return on the second branch 313 through the backflush liquid, only when it is determined that Δq1 < q ≤ Δq1 + Δq2 is satisfied will blood return be performed on the second branch 313, which will cause the second branch 313 to wait for a relatively long time to start the blood return operation, resulting in a decrease in the plasma temperature within the second branch 313. If the plasma temperature within the second branch 313 is too low, this will cause discomfort symptoms in the patient. The preset safe temperature refers to the lowest liquid temperature when the venous pipeline 311 is transfused back into the human body. The preset safe temperature is pre-set by technical personnel. For example, the preset safe temperature is 30°C. Only when the liquid temperature of the venous pipeline 311 is greater than or equal to the preset safe temperature will the liquid transfused back into the human body through the venous pipeline 311 be in a safe state; on the contrary, when the liquid temperature (the second detected temperature T2) of the venous pipeline 311 is lower than the preset safe temperature, it indicates that the liquid temperature within the second branch 313 is too low, which makes the liquid transfused back into the human body through the venous pipeline 311 cause discomfort symptoms in the human body and even endanger the patient's life safety.

[0114] When it is determined that the second detected temperature T2 is lower than the preset safe temperature, a prompt is sent to the user through the temperature prompt message: The temperature of the liquid within the second branch 313 is too low. Therefore, as soon as the user receives the temperature prompt message, they will handle the temperature failure of the second branch 313 during the blood return stage.

[0115] Embodiment of the blood purification device:

[0116] The blood purification device in this embodiment includes components such as a main unit 1 and a display screen 2. The display screen 2 is a human-computer interactive touch screen. A circuit board capable of realizing interactive communication with the display screen 2 is provided inside the main unit 1. A processor and a memory are provided on the circuit board. The memory stores a computer program. When the computer program is executed by the processor, each step of the blood return control method of the above-mentioned blood purification device is realized.

[0117] For example, the computer program can be divided into one or more modules. One or more modules are stored in the memory and executed by the processor to complete each module of the present invention. One or more modules can be a series of computer program instruction segments capable of completing specific functions, and these instruction segments are used to describe the execution process of the computer program in the terminal device.

[0118] The processor referred to in this invention can be a Central Processing Unit (CPU), or other general-purpose processors, digital signal processors (DSPs), application-specific integrated circuits (ASICs), field-programmable gate arrays (FPGAs), or other programmable logic devices, discrete gate or transistor logic devices, discrete hardware components, etc. A general-purpose processor can be a microprocessor or any conventional processor. The processor is the control center of an electrical appliance, connecting all parts of the appliance through various interfaces and lines.

[0119] Memory can be used to store computer programs and / or modules. The processor implements various functions of an electrical appliance by running or executing the computer programs and / or modules stored in the memory, and by accessing data stored in the memory. Memory can mainly include a program storage area and a data storage area. The program storage area can store the operating system, at least one application program required for a function, etc.; the data storage area can store data created based on the use of the electrical appliance, etc. Furthermore, memory can include high-speed random access memory, and can also include non-volatile memory, such as hard disks, RAM, plug-in hard disks, smart media cards (SMC), secure digital cards (SD cards), flash cards, at least one disk storage device, flash memory device, or other volatile solid-state storage devices.

[0120] Examples of computer-readable storage media:

[0121] If the computer program stored in the memory of the blood purification device is implemented as a software functional unit and sold or used as an independent product, it can be stored in a computer-readable storage medium. Based on this understanding, all or part of the processes in the methods of the above embodiments of the present invention can also be implemented by a computer program instructing related hardware. This computer program can be stored in a computer-readable storage medium, and when executed by a processor, it can implement the various steps of the blood return control method of the above-described blood purification device.

[0122] Computer programs include computer program code, which can be in the form of source code, object code, executable files, or certain intermediate forms. Computer-readable media can include: any entity or device capable of carrying computer program code, recording media, USB flash drives, portable hard drives, magnetic disks, optical disks, computer memory, read-only memory (ROM), random access memory (RAM), electrical carrier signals, telecommunication signals, and software distribution media, etc. It should be noted that the content included in computer-readable media can be appropriately added to or subtracted according to the requirements of legislation and patent practice in a jurisdiction. For example, in some jurisdictions, according to legislation and patent practice, computer-readable media do not include electrical carrier signals and telecommunication signals.

[0123] The above embodiments are merely preferred examples of the present invention and are not intended to limit the scope of the present invention. Therefore, all equivalent changes or modifications made to the structure, features and principles of the present invention in accordance with the claims of the present invention should be included in the scope of the present invention patent application.

Claims

1. A blood purification device, characterized in that, The device includes a host and a display screen. The host has a circuit board that can communicate with the display screen. The circuit board has a processor and a memory. The memory stores a computer program. When the computer program is executed by the processor, it implements the blood return control method of the blood purification device as described below. The extracorporeal circulation circuit of the blood purification device includes a reservoir bag, an arterial line, a blood purifier, and a venous line. The input end of the arterial line is connected to an artery in the human body, the output end of the arterial line is connected to the input end of the blood purifier, the output end of the blood purifier is connected to the input end of the venous line, and the output end of the venous line is connected to a vein in the human body. The venous line is equipped with a blood detector for detecting the color of the liquid. The reservoir bag can be connected to one of the input ends of the arterial line, the blood purifier, and the venous line. The reservoir bag stores backflushing fluid. The blood return control method of the blood purification device includes: When the continuous purification time of the blood purifier is greater than or equal to the preset purification time, the system controls the connection between the reservoir bag and one of the input ends of the arterial line, the blood purifier, and the venous line, so that the blood purification device enters the blood return phase operation. Detect the cumulative decrease in the backfill fluid within the storage bag. ; Determine the cumulative reduction amount Is it greater than the preset safety limit? If so, then detect the color of the fluid within the venous tubing; It also determines whether the color of the fluid in the intravenous tubing is red. If not, it controls the blood purification device to stop connecting to the storage bag to complete the blood return stage operation.

2. The blood purification device according to claim 1, characterized in that: When the reservoir bag is connected to the input end of the arterial tubing for the blood return phase operation, the blood return control method of the blood purification device further includes: The first detection flow rate of the backflushing fluid connected to the arterial tubing is detected. And based on the first detected flow rate Obtain the preset security amount And the preset safety amount With the first detection flow There is a positive correlation between them; Alternatively, detect the first flow rate of the backflushing fluid connected to the arterial tubing. and control the first detection flow. Decrease according to the preset decreasing pattern.

3. The blood purification device according to claim 1, characterized in that: The blood return control method of the blood purification device also includes: When the continuous purification time of the blood purifier is less than the preset purification time, the blood flow in the artery into which the arterial tubing is connected is detected to obtain a second detection flow rate. ; Calculate and obtain the preset constant flow rate ; When the continuous purification time of the blood purifier is greater than or equal to the preset purification time, and when the reservoir bag is connected to the input end of the arterial tubing for the blood return phase, the arterial tubing is controlled to operate at the preset constant flow rate. Connect the backflush fluid.

4. The blood purification device according to claim 1, characterized in that: The blood return control method of the blood purification device also includes: When the color of the fluid in the intravenous tubing is determined to be red, the blood purification device is controlled to issue a backflow fault alarm signal, and the fluid flow rate in the intravenous tubing is detected to obtain a third detection flow rate. ; Determine the third detection flow rate Is the flow rate less than the preset minimum? If so, the blood purification device will be controlled to send a signal indicating a blockage in the venous tubing. If not, then the blood return calibration volume of the blood purification device is obtained based on the RGB value of the color of the fluid in the intravenous tubing. Next, determine whether it satisfies the condition. If so, the blood purification device is controlled to stop connecting to the storage bag to complete the blood return stage operation; Among them, the blood return calibration amount There is a positive correlation between the color RGB value of the fluid in the vein and the venous line.

5. The blood purification device according to claim 1, characterized in that: The inner diameter of the arterial conduit is equal to the inner diameter of the venous conduit, and the blood return control method of the blood purification device further includes: Detecting the length of the arterial conduit And detect the length of the vein. ; When satisfied At that time, determine the cumulative reduction amount. Is it less than the blood volume of the arterial conduit? If so, the system connects the reservoir bag to the input end of the arterial tubing; otherwise, the system connects the reservoir bag to the input end of the blood purifier.

6. The blood purification device according to claim 1, characterized in that: The blood return control method of the blood purification device also includes: When satisfied When the time is right, the reservoir bag is connected to the input end of the arterial tubing, and the arterial tubing is connected to the return fluid at a first preset flow rate. The blood volume of the arterial tubing; When satisfied When the time is right, the system connects the storage bag to the input of the blood purifier, controls the blood purifier to receive the return fluid at a second preset liquid flow rate, and controls the multi-functional hammer to strike the input or output of the blood purifier at a preset striking frequency. The blood volume of the blood purifier; When satisfied When the time is right, the system controls the connection between the storage bag and the input end of the intravenous line, and controls the intravenous line to connect to the flushing fluid at a third preset fluid flow rate; Wherein, the first preset liquid flow rate is greater than the second preset liquid flow rate, and the second preset liquid flow rate is greater than the third preset liquid flow rate.

7. The blood purification device according to claim 1, characterized in that: When the reservoir bag is connected to the input end of the arterial tubing for the blood return phase operation, the blood return control method of the blood purification device further includes: The temperature of the backfill fluid inside the storage bag is detected to obtain a first detection temperature. And detect the temperature of the fluid in the intravenous line to obtain a second detection temperature. ; Determine if it satisfies If so, the blood purification device is controlled to issue a fault signal for the backflushing fluid temperature. in, This is the preset temperature difference value.

8. The blood purification device according to claim 1, characterized in that: The blood purifier is a plasma separator. The inlet end of the venous line is equipped with a venous reservoir. The blood cell outlet end of the plasma separator is connected to the first inlet end of the venous reservoir via a first branch. The plasma outlet end of the plasma separator is connected to the second inlet end of the venous reservoir via a second branch. The second branch is equipped with an adsorption column and a filtration pump. A first on / off clamp is provided on the first branch near the blood cell outlet end of the plasma separator, and a second on / off clamp is provided on the second branch near the plasma outlet end of the plasma separator. The blood return control method of the blood purification device also includes: Calculate and obtain the first safety quantity Second safety quantity ,in The blood volume of the arterial conduit. The blood volume of the blood purifier. The blood volume of the venous tubing. The blood volume of the first branch. The blood volume of the second branch, The blood volume of the venous chamber; When the judgment is satisfied When the time is right, the reservoir bag is connected to the input end of the arterial line, and the arterial line is connected to the backflushing fluid at a first preset flow rate. The first on / off clamp is opened and the second on / off clamp is closed. When the judgment is satisfied When the flow is complete, the system connects the reservoir bag to the input end of the arterial tubing, controls the arterial tubing to receive the backflushing fluid at a second preset flow rate, controls the second on / off clamp to open and the first on / off clamp to close, and detects the fluid temperature in the venous tubing to obtain a second detection temperature. When determining the second detection temperature When the temperature is lower than the preset safe temperature, the blood purification device is controlled to issue a temperature warning message, wherein the first preset flow rate is greater than the second preset flow rate; When the judgment is satisfied If so, determine whether the color of the fluid in the venous tubing is red.

9. A computer-readable storage medium having a computer program stored thereon, characterized in that: When the computer program is executed by the processor, it implements each step of the blood return control method of the blood purification device according to any one of claims 1 to 8.

Images