Anti-collision detection method, control method of sample analyzer and related equipment

By installing a signal change detection device in the sample analyzer to detect the signal change value during the downward movement of the liquid transfer mechanism, it can determine whether an obstacle has been encountered and control the second liquid transfer mechanism, thus solving the problem of sample needle bending and deformation when the test tube is capped, improving liquid transfer efficiency and equipment protection.

CN115684616BActive Publication Date: 2025-12-16SHENZHEN DYMIND BIOTECH
View PDF 2 Cites 0 Cited by

Patent Information

Application Number
CN202110875791.2
Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
Filing Date
2021-07-30
Publication Date
2025-12-16
Estimated Expiration
2041-07-30

AI Technical Summary

Technical Problem

When the test tubes in the sample analyzer are capped, the sample needle may bend and deform, which will prolong the sample acquisition time and reduce efficiency.

Method used

A signal change detection device is installed in the sample analyzer. By detecting the signal change value during the downward movement of the liquid transfer mechanism, it is determined whether an obstacle is encountered. Based on the detection result, the second liquid transfer mechanism is controlled to avoid collision with the obstacle.

Benefits of technology

It improves liquid transfer efficiency, protects the liquid transfer mechanism, avoids deformation or damage, and ensures the normal operation of the sample analyzer.

✦ Generated by Eureka AI based on patent content.

Smart Images

  • Figure CN115684616B_ABST
    Figure CN115684616B_ABST
Patent Text Reader

Abstract

Embodiments of the present application disclose a sample analyzer control method and related equipment. The sample analyzer includes a first liquid transfer mechanism and a second liquid transfer mechanism, the first liquid transfer mechanism is fixed by a fixed block, and a signal change detection device is arranged between the first liquid transfer mechanism and the fixed block, so that the detection signal value can be determined according to the change value of the signal change detection device in the process of the first liquid transfer mechanism moving downward from the current detection position; according to the detection signal value and a preset standard signal value, whether the first liquid transfer mechanism encounters an obstacle in the moving downward process is judged, and a detection result is obtained; the second liquid transfer mechanism is controlled according to the detection result of the current detection position, so that the first liquid transfer mechanism can be used for obstacle detection, and the control of the second liquid transfer mechanism is realized based on the detection result, without the need for the second liquid transfer mechanism to detect the obstacle, thereby improving the efficiency.
Need to check novelty before this filing date? Find Prior Art

Description

TECHNICAL FIELD

[0001] The present application relates to the technical field of computer, and in particular, to a collision detection method, a control method of a sample analyzer and related equipment. BACKGROUND

[0002] The sample analyzer usually uses a test tube to contain a sample. In order to avoid pollution, some test tubes are covered. The test tube is directly sampled in a covered state, which may cause the sample needle to be bent and deformed, and needs to be replaced, resulting in the time for obtaining the sample from the test tube being prolonged and the efficiency of obtaining the sample being reduced. SUMMARY

[0003] Therefore, it is necessary to propose a control method of a sample analyzer and related equipment to effectively improve the transfer efficiency of the liquid.

[0004] In a first aspect, an embodiment of the present application provides a control method of a sample analyzer, the sample analyzer comprising a first liquid transfer mechanism and a second liquid transfer mechanism, the first liquid transfer mechanism being fixed through a fixed block, and a signal change detection device being arranged between the first liquid transfer mechanism and the fixed block; the control method comprising:

[0005] determining a detection signal value according to a change value of the signal change detection device in a process of the first liquid transfer mechanism moving downward from a current detection position;

[0006] judging whether the first liquid transfer mechanism encounters an obstacle in the process of moving downward according to the detection signal value and a preset standard signal value, to obtain a detection result; the standard signal value being determined in advance based on a signal change value of the first liquid transfer mechanism in a normal moving downward process;

[0007] controlling the second liquid transfer mechanism according to the detection result of the current detection position.

[0008] In a second aspect, an embodiment of the present application provides a control device of a sample analyzer, the sample analyzer comprising a first liquid transfer mechanism and a second liquid transfer mechanism, the first liquid transfer mechanism being fixed through a fixed block, and a signal change detection device being arranged between the first liquid transfer mechanism and the fixed block; the control device comprising:

[0009] a signal acquisition module, configured to determine a detection signal value according to a change value of the signal change detection device in a process of the first liquid transfer mechanism moving downward from a current detection position;

[0010] detecting a detection signal value according to the signal change value of the signal change detection device during the downward movement of the first liquid transfer mechanism from the current detection position;

[0011] controlling the second liquid transfer mechanism according to the detection result of the current detection position.

[0012] In a third aspect, an embodiment of the present application provides a computer readable storage medium storing a computer program, the computer program being executed by a processor to cause the processor to perform the following steps:

[0013] detecting a detection signal value according to the signal change value of the signal change detection device during the downward movement of the first liquid transfer mechanism from the current detection position;

[0014] detecting a detection result according to the detection signal value and a preset standard signal value, the standard signal value being determined in advance based on the signal change value of the first liquid transfer mechanism during normal downward movement;

[0015] controlling the second liquid transfer mechanism according to the detection result of the current detection position.

[0016] The control method of the sample analyzer provided by the embodiment of the present application includes a first liquid transfer mechanism and a second liquid transfer mechanism, the first liquid transfer mechanism is fixed by a fixed block, and a signal change detection device is arranged between the first liquid transfer mechanism and the fixed block, so that the change value of the signal change detection device during the downward movement of the first liquid transfer mechanism from the current detection position can be obtained as a detection signal value; a detection result is detected according to the detection signal value and a preset standard signal value, the standard signal value being determined in advance according to the signal change value of the first liquid transfer mechanism during normal downward movement; and the second liquid transfer mechanism is controlled according to the detection result of the current detection position, so that the detection of the obstacle can be performed by the first liquid transfer mechanism, and the control of the second liquid transfer mechanism is realized based on the detection result, without the need for the second liquid transfer mechanism to detect the obstacle, the liquid can be obtained by the first liquid transfer mechanism and the second liquid transfer mechanism, and the efficiency is improved. BRIEF DESCRIPTION OF DRAWINGS

[0017] To more clearly illustrate the technical solutions in the embodiments of the present invention or the prior art, the drawings used in the description of the embodiments or the prior art will be briefly introduced below. Obviously, the drawings described below are only some embodiments of the present invention. For those skilled in the art, other drawings can be obtained based on these drawings without creative effort.

[0018] in:

[0019] Figure 1 Here is a flowchart of a collision avoidance detection method in one embodiment;

[0020] Figure 2 This is a flowchart of a method for detecting whether a liquid transfer mechanism encounters an obstacle during its downward movement, as shown in one embodiment.

[0021] Figure 3 This is a flowchart of a control method for a sample analyzer in one embodiment;

[0022] Figure 4 This is a flowchart of a detection result acquisition method in one embodiment;

[0023] Figure 5 A flowchart of a control method for a sample analyzer in another embodiment;

[0024] Figure 6 This is a flowchart of the control method for the sample analyzer in yet another embodiment;

[0025] Figure 7 This is a structural block diagram of a collision avoidance detection device in one embodiment;

[0026] Figure 8 This is a structural block diagram of the control device of a sample analyzer in one embodiment;

[0027] Figure 9 This is a structural block diagram of a computer device in one embodiment. Detailed Implementation

[0028] The technical solutions of the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only some embodiments of the present invention, and not all embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of the present invention.

[0029] like Figure 1 As shown, a collision avoidance detection method is proposed and applied to a liquid transfer mechanism. The liquid transfer mechanism is fixed by a fixing block, and a signal change detection device is provided between the liquid transfer mechanism and the fixing block. The method includes:

[0030] In step 102, a detection signal value is determined according to the change value of the signal change detection device during the lowering of the liquid transfer mechanism.

[0031] The liquid transfer mechanism refers to a mechanism for transferring liquid, such as a sample needle, a reagent needle, etc. in a sample analyzer. The sample needle can be used to transfer a sample, and the reagent needle can be used to transfer a reagent.

[0032] To achieve the anti-collision detection, the liquid transfer mechanism can be fixed by a fixed block, and a signal change detection device is arranged between the liquid transfer mechanism and the fixed block, so that the change value of the signal change detection device during the lowering of the liquid transfer mechanism can be obtained, and the change value is used to determine whether the liquid transfer mechanism encounters an obstacle during the lowering.

[0033] It can be understood that the liquid transfer mechanism provided with the signal change detection device can be referred to as a liquid transfer mechanism with anti-collision detection function, and the signal change detection device can be arranged to improve the accuracy of the detection signal value for subsequent further processing based on the detection signal value.

[0034] In step 104, it is determined whether the liquid transfer mechanism encounters an obstacle during the lowering according to the detection signal value and a preset standard signal value. The standard signal value is a critical value of the detection signal value that is determined in advance according to the signal change value of the signal change detection device during the normal lowering of the liquid transfer mechanism.

[0035] The preset standard signal value refers to a critical value of the detection signal value that is used to determine whether the liquid transfer mechanism encounters an obstacle during the normal lowering. The normal lowering refers to the lowering without an obstacle. In one possible implementation, the standard signal value can be determined according to the puncture pressure range when the liquid transfer mechanism punctures the rubber plug of a test tube. For example, the minimum value of the puncture pressure range when the liquid transfer mechanism punctures the rubber plug of a test tube can be used as the standard signal value, so that no matter what object the liquid transfer mechanism encounters during the lowering, it is considered as an obstacle. Further, in the case where it is determined that there is an obstacle, it can be determined again whether the encountered obstacle is a puncturable obstacle based on the detection signal value and the puncture pressure range. It can be understood that in actual applications, the size of the standard signal value can be set according to specific needs, which is not limited herein.

[0036] In step 106, if the liquid transfer mechanism encounters an obstacle, the liquid transfer mechanism is controlled according to a preset strategy.

[0037] The preset strategy refers to a manner preset for controlling the liquid transfer mechanism when an obstacle is encountered. In one possible implementation, if the liquid transfer mechanism encounters an obstacle and the obstacle is not an object requiring puncture, the preset strategy can be to control the liquid transfer mechanism to move upward or stop moving downward to avoid deformation and damage of the liquid transfer mechanism caused by continuous downward movement, and the like. In another possible implementation, if the liquid transfer mechanism encounters an obstacle and the obstacle is a rubber plug, the preset strategy can be to control the liquid transfer mechanism to puncture at a constant pressure. Specifically, based on the change value of the signal change detection device obtained, the motor power of the sample analyzer can be adjusted in real time, so that the liquid transfer mechanism can puncture the rubber plug at a constant pressure, preventing excessive instantaneous pressure during puncture and causing damage to the liquid transfer mechanism, thereby protecting the liquid transfer mechanism. In the embodiments of the present application, when the liquid transfer mechanism encounters an obstacle, the liquid transfer mechanism is controlled, thereby effectively preventing the liquid transfer mechanism from colliding with the obstacle, achieving good anti-collision effect, and avoiding damage to the liquid transfer mechanism, thereby protecting the liquid transfer mechanism.

[0038] The anti-collision detection method determines a detection signal value according to a change value of the signal change detection device of the liquid transfer mechanism during downward movement, determines whether the liquid transfer mechanism encounters an obstacle during downward movement according to the detection signal value and a preset standard signal value, and controls the liquid transfer mechanism according to a preset strategy if the liquid transfer mechanism encounters an obstacle. The standard signal value is determined in advance according to a signal change value of the signal change detection device of the liquid transfer mechanism during normal downward movement. The method can effectively determine whether an obstacle is encountered and control the liquid transfer mechanism when an obstacle is encountered, thereby avoiding damage to the liquid transfer mechanism caused by collision with the obstacle and protecting the liquid transfer mechanism.

[0039] In one embodiment, the detection signal value is determined according to a change value of the signal change detection device of the liquid transfer mechanism within a preset time length, including: collecting an electrical signal change value of the signal change detection device of the liquid transfer mechanism during downward movement by using a sensor, and determining the detection signal value according to the electrical signal change value; or collecting an electrical signal change value of the signal change detection device of the liquid transfer mechanism during downward movement by using a sensor, calculating a pressure value according to the electrical signal change value of the signal change detection device, and taking the pressure value as the detection signal value.

[0040] The signal change detection device can be a pressure detection device, for example, specifically a pressure-sensitive resistor. Specifically, the electrical signal change value of the signal change detection device refers to a resistance change value or a current change value of the pressure-sensitive resistor. The resistance value and the current value can be determined according to the resistance change value or the current change value, and the resistance value or the current value is taken as the detection signal value. Alternatively, after the signal change value of the pressure-sensitive resistor is collected by the sensor, the electrical signal change value can be converted into a pressure value by using a conversion formula between the resistance change value and the pressure value or a conversion formula between the current change value and the pressure value, so as to obtain the detection signal value. The electrical signal change value of the pressure-sensitive resistor is collected by the sensor, so that the electrical signal change value can be accurately obtained, the detection signal value is obtained according to the electrical signal change value, and the accuracy of the detection signal value is improved.

[0041] As shown in FIG. 1, Figure 2 According to the detection signal value and the preset standard signal value, it is determined whether the liquid transfer mechanism encounters an obstacle during the downward movement, including:

[0042] If the detection signal value is greater than the standard signal value, it is determined that the liquid transfer mechanism encounters an obstacle.

[0043] If the detection signal value is less than or equal to the standard signal value, it is determined that the liquid transfer mechanism does not encounter an obstacle.

[0044] In the embodiment of the present application, the detection signal value is taken as the pressure value. When the detection signal value is greater than the standard signal value, it indicates that the pressure value of the liquid transfer mechanism during the downward movement is relatively large, and it is determined that the liquid transfer mechanism encounters an obstacle. When the detection signal value is less than or equal to the standard signal value, it indicates that the pressure value of the liquid transfer mechanism during the downward movement is relatively small, and it is determined that the liquid transfer mechanism does not encounter an obstacle. In the embodiment, the detection signal value is compared with the preset standard signal value, so that the efficient detection of whether the liquid transfer mechanism encounters an obstacle during the downward movement is realized.

[0045] It can be understood that, in a feasible implementation, it can be further determined whether the encountered obstacle is a puncturable obstacle, such as a rubber plug. Specifically, in the case of determining that an obstacle is encountered based on the detection signal value and the standard signal value, the detection signal value can be compared with a puncture pressure range value. If the detection signal value is within the preset puncture pressure range in which the liquid transfer mechanism normally punctures, it can be determined that the obstacle is a puncturable obstacle, and the liquid transfer mechanism can be further controlled to puncture the obstacle at a constant pressure. If the detection signal value is not within the puncture pressure range, it can be determined that the obstacle is not a puncturable obstacle, and the liquid transfer mechanism is controlled to move upward or stop moving downward, so as to avoid deformation or damage of the liquid transfer mechanism.

[0046] It should be noted that the liquid transfer mechanism with the anti-collision detection function in the above embodiment can be a sample needle or a reagent needle. In a feasible implementation, the sample analyzer can be configured to have the sample needle with the anti-collision detection function, the reagent needle with the anti-collision detection function, or both the sample needle and the reagent needle with the anti-collision detection function. It can be understood that, if the sample analyzer is configured to have both the sample needle and the reagent needle with the anti-collision detection function, the sample analyzer can control the sample needle to perform anti-collision detection on the test tube containing the sample, and control the reagent needle to perform anti-collision detection on the test tube containing the reagent. The anti-collision detection of the sample needle and the anti-collision detection of the reagent needle can be independent of each other.

[0047] In another feasible implementation, one of the sample needle and the reagent needle in the sample analyzer can be configured to have the anti-collision detection function. For example, the sample needle can be configured to have the anti-collision detection function, and the reagent needle can not be configured to have the anti-collision detection function. In this case, when the reagent is transferred, the anti-collision detection function of the sample needle can be used to perform anti-collision detection on the reagent site, and the reagent needle can be controlled to perform reagent transfer when it is determined that there is no obstacle. For another example, the reagent needle can be configured to have the anti-collision detection function, and the sample needle can not be configured to have the anti-collision detection function. In this case, when the sample is transferred, the anti-collision detection function of the reagent needle can be used to perform anti-collision detection on the sample site, and the sample needle can be controlled to perform sample transfer when it is determined that there is no obstacle.

[0048] In order to better understand the above technical solutions, as shown in Figure 3 A control method of a sample analyzer is provided. The sample analyzer includes a first liquid transfer mechanism and a second liquid transfer mechanism. The first liquid transfer mechanism is fixed by a fixed block, and a signal change detection device is arranged between the first liquid transfer mechanism and the fixed block. That is, the first liquid transfer mechanism has an anti-collision detection function. The control method includes the following steps.

[0049] In step 202, a detection signal value is determined according to a change value of the signal change detection device during a downward movement of the first liquid transfer mechanism from a current detection site.

[0050] In step 204, a detection result is obtained by determining whether the first liquid transfer mechanism encounters an obstacle during the downward movement according to the detection signal value and a preset standard signal value. The standard signal value is determined in advance according to a signal change value of the signal change detection device during a normal downward movement of the liquid transfer mechanism.

[0051] In step 206, the second liquid transfer mechanism is controlled according to the detection result of the current detection site.

[0052] It should be noted that, in the case that the first liquid transfer mechanism has the anti-collision detection function, the second liquid transfer mechanism can have the anti-collision detection function or can not have the anti-collision detection function, and in actual application, the specific needs can be set, which is not limited here.

[0053] The second liquid transfer mechanism can have one or multiple detection positions.

[0054] In order to determine whether the detection position of the second liquid transfer mechanism has an obstacle, the change value of the signal change detection device during the downward movement of the first liquid transfer mechanism from the current detection position can be used to determine the detection signal value, and then the detection signal value and the standard signal value are compared to determine whether the first liquid transfer mechanism encounters an obstacle during the downward movement, and the detection result is obtained. It should be noted that, when the number of detection positions is one, the detection result of the one detection position can be used to control the second liquid transfer mechanism, and when the number of detection positions is multiple, the detection results of the multiple detection positions can be determined by the first liquid transfer mechanism according to the method in steps 202 and 204, and then the content in step 206 is executed. The result of one detection position can be encountering an obstacle or not encountering an obstacle.

[0055] It can be understood that, the method of using the first liquid transfer mechanism to detect obstacles and controlling the second liquid transfer mechanism according to the detection result is similar to using the first liquid transfer mechanism to "explore the road" and controlling the second liquid transfer mechanism according to the "road exploration" result, which can improve the efficiency of liquid transfer, avoid deformation or damage of the second liquid transfer mechanism, and ensure the normal operation of the sample analyzer and improve the working efficiency of the sample analyzer.

[0056] In one embodiment, the detection signal value is determined according to the change value of the signal change detection device during the downward movement of the first liquid transfer mechanism from the current detection position, which includes: using a sensor to collect the electrical signal change value of the signal change detection device during the downward movement of the liquid transfer mechanism, and determining the detection signal value according to the electrical signal change value; or using a sensor to collect the electrical signal change value of the signal change detection device during the downward movement of the liquid transfer mechanism, calculating the pressure value according to the electrical signal change value of the signal change detection device, and determining the detection signal value according to the pressure value.

[0057] The aforementioned signal change detection device can be a pressure detection device, specifically a piezoresistive resistor. Specifically, the electrical signal change value of the signal change detection device refers to the change in resistance or current of the piezoresistive resistor, acquired by a sensor. The resistance and current values ​​can be determined based on these changes and used as the detection signal value. Alternatively, after acquiring the signal change value of the piezoresistive resistor using a sensor, the electrical signal change value can be converted into a pressure value using a conversion formula between resistance and pressure, or between current and pressure, thus obtaining the detection signal value. By acquiring the electrical signal change value of the piezoresistive resistor using a sensor, accurate acquisition of the electrical signal change value is achieved, and the detection signal value is obtained based on this change, thereby improving the accuracy of the detection signal value.

[0058] like Figure 4 As shown, in one embodiment, based on the detection signal value and a preset standard signal value, it is determined whether the first liquid transfer mechanism encounters an obstacle during its downward movement, and the detection result is obtained, including:

[0059] Step 204A: If the detected signal value is greater than the standard signal value, it is determined that the first liquid transfer mechanism has encountered an obstacle;

[0060] Step 204B: If the detected signal value is less than or equal to the standard signal value, it is determined that the first liquid transfer mechanism has not encountered an obstacle.

[0061] In this embodiment, when the detected signal value is greater than the standard signal value, it indicates that the pressure value of the first liquid transfer mechanism is relatively high during the downward movement, thus determining that the first liquid transfer mechanism has encountered an obstacle. When the detected signal value is less than or equal to the standard signal value, it indicates that the pressure value of the first liquid transfer mechanism is relatively low during the downward movement, thus determining that the first liquid transfer mechanism has not encountered an obstacle. This embodiment achieves efficient detection of whether the liquid transfer mechanism has encountered an obstacle during the downward movement by simply comparing the detected signal value with a preset standard signal value.

[0062] It should be noted that after obtaining the detection result of the current detection position, the first liquid transfer mechanism will move out of the current detection position.

[0063] like Figure 5 As shown, in one embodiment, before controlling the second liquid transfer mechanism based on the detection result of the current detection position, the method further includes:

[0064] Step 208: Record the detection result of the current detection position;

[0065] If there is still an undetected detection position, any one of the undetected detection positions is taken as the current detection position, and the process of determining the detection signal value according to the change value of the signal change detection device in the process of moving down from the current detection position by the first liquid transfer mechanism is executed again.

[0066] If there is no undetected detection position, the step of controlling the second liquid transfer mechanism according to the detection result of the current detection position is executed continuously.

[0067] In the embodiment of the present application, the detection positions of the second liquid transfer mechanism can be multiple, and after the detection of each detection position is completed, the first liquid transfer mechanism records the detection result of the detection position, and further determines whether there is still an undetected detection position. If there is, it indicates that there is still a detection position that needs to be detected for anti-collision detection, and the next detection position can be taken as the current detection position, and the step 202 is executed again. If there is no undetected detection position, it indicates that the detection of the detection position has been completed, and the step of controlling the second liquid transfer mechanism according to the detection result of the current detection position can be executed continuously. In this way, the detection of multiple detection positions can be realized, and the control of the second liquid transfer mechanism according to the detection results of multiple detection positions can be realized, thereby improving the efficiency of liquid transfer.

[0068] As shown in FIG. 2, in one embodiment, the step of controlling the second liquid transfer mechanism according to the detection result of the current detection position includes: Figure 6

[0069] Step 206A, determining the number of first target detection positions with a detection result of no obstacle encountered based on the recorded detection results.

[0070] Step 206B, if the number of first target detection positions is greater than a preset first value, controlling the second liquid transfer mechanism to move down from the first target detection position and transfer liquid.

[0071] The first target detection position refers to a detection position with a detection result of no obstacle encountered. The preset first value refers to a critical value of the number of current detection positions that can perform liquid transfer operation. Specifically, the number of first target detection positions with a detection result of no obstacle encountered is determined based on the recorded detection results, and when the number of first target detection positions is greater than the preset first value, it is determined that liquid transfer operation can be performed, wherein the first value can be 1, or 2 or other values. In the case where liquid transfer operation can be performed, the second liquid transfer mechanism can be controlled to move down from the first target detection position and transfer liquid, thereby realizing safe operation of the sample analyzer and improving the control efficiency of the sample analyzer.

[0072] ​In one embodiment, the control method of the sample analyzer further comprises: if the number of the first target detection positions is greater than a preset second value, determining a second target detection position encountering an obstacle, and locking the reagent on the second target detection position.

[0073] The second target detection position refers to the current detection position encountering an obstacle. The preset second value refers to a critical value of the number of detection positions not encountering obstacles when locking the detection positions encountering obstacles. When the number of the first target detection positions is greater than the preset second value, it indicates that the number of required detection positions meets the standard, and the test process can be performed. At this time, in order to avoid the interference of the detection positions encountering obstacles on the test process, the second target detection position encountering an obstacle needs to be determined and locked. Specifically, if the second target detection position is a test tube containing a sample, the test tube containing the sample is locked. If the second target detection position is a test tube containing a reagent, the test tube containing the reagent is locked to avoid the second liquid transfer mechanism reaching the second target detection position and being damaged by impact when moving down to take liquid, thereby protecting the second liquid transfer mechanism.

[0074] Further, in a feasible implementation, if there are multiple detection positions, the detection positions may belong to different test items. In order to be able to implement the test, each item needs to have a preset number of, for example, one first target detection position not encountering an obstacle. After determining the first target detection position, the number of first target detection positions of each test item can be determined based on the type of the item corresponding to each first target detection position. If the number of first target detection positions of each test item is greater than or equal to the preset number, it indicates that even in the presence of a second target detection position encountering an obstacle, the test requirement can still be met. At this time, the second target detection position can be locked to avoid interference of the second target detection position. If the number of first target detection positions of one or more test items in each test item is less than the preset number, it indicates that the number of first target detection positions not encountering an obstacle is insufficient to complete the test process. At this time, an alarm information is output.

[0075] Therefore, in one embodiment, the control method of the sample analyzer further comprises:

[0076] The display interface displays the alarm information and a button corresponding to the alarm information. The alarm information contains the second target detection position, and the alarm information is used to prompt to clear the obstacle of the second target detection position. It should be noted that after the alarm information is output, the sample analyzer will pause the operation.

[0077] It can be understood that the second target detection position is displayed, so that the operator can clearly know which detection position has an obstacle, and the obstacle can be removed. Further, after the obstacle is removed, the test can be continued, the deformation or damage of the second liquid transfer mechanism caused by collision with the obstacle is avoided, and the test effect is improved.

[0078] In one embodiment, the control method of the sample analyzer further includes: if the click operation on the elimination button is detected, controlling the first liquid transfer mechanism to sequentially move downward again from each second target detection position to detect whether an obstacle is encountered; if no obstacle is encountered, canceling the display of the alarm information and the elimination button; and if an obstacle is encountered, updating the alarm information using the third target detection position where the obstacle is encountered, and displaying the updated alarm information.

[0079] In this embodiment, the operator can click the elimination button. When the click operation on the elimination button is detected, in order to determine whether the obstacle of the second target detection position has been removed or whether the test can continue, the first liquid transfer mechanism can be controlled to sequentially move downward again from each second target detection position to detect whether an obstacle is encountered. If no obstacle is encountered in each second target detection position, the display of the alarm information and the elimination button is canceled, and in this case, the second liquid transfer mechanism can continue to be controlled to transfer the liquid. If some of the second target detection positions do not encounter obstacles, and some of the second target detection positions still have obstacles, the first target detection position described above can be updated using the detection position where no obstacle is encountered, and the number of first target detection positions of each test item can be updated. The alarm information described above can be updated using the third target detection position where the obstacle is encountered when the second target detection position is detected, and the updated alarm information is displayed. If the number of first target detection positions of each test item after the update is greater than the preset number, the test can continue even if there is a third target detection position where an obstacle is encountered. It can be understood that if it is determined that the second target detection position does not encounter an obstacle during the re-detection, it indicates that the obstacle on the second target detection position has been removed, and the second liquid transfer mechanism can transfer the liquid at the second target detection position. Therefore, the lock on the second target detection position can be released.

[0080] It should be noted that one possible scenario of the control method of the sample analyzer described above is to perform the cover opening detection. When an obstacle is encountered, it is determined that the cover is in an unopened state. If no obstacle is encountered, it is determined that the cover is in an opened state.

[0081] In one specific embodiment, when the sample analyzer is a coagulation analyzer, the first liquid transfer mechanism is a reagent needle in the coagulation analyzer, the second liquid transfer mechanism is a sample needle in the coagulation analyzer, generally, the sample needle does not have an anti-collision detection function, the reagent needle has an anti-collision detection function, a detection table of the coagulation analyzer is provided with a sample area and a reagent area arranged in sequence, wherein, a part of the reagent area close to the sample area is provided with a dilution liquid level, a dilution liquid bottle can be placed, and the sample needle can reach a position of the dilution liquid bottle to suck the dilution liquid. In one feasible implementation, after the coagulation analyzer is started, the reagent needle with the anti-collision detection function can be controlled to perform anti-collision detection on the position of the dilution liquid bottle to realize uncapping detection of the dilution liquid bottle, determine the uncapping condition, if an obstacle is detected, it is determined that the dilution liquid bottle is in an uncapped state, if no obstacle is detected, it is determined that the dilution liquid bottle is in a capped state, after the uncapping detection of the dilution liquid bottle is completed, the sample needle can be controlled according to the uncapping detection result of the dilution liquid bottle, for example, if it is detected that all the dilution liquid bottles are in the uncapped state, it is determined that the sample needle does not suck the dilution liquid from the dilution liquid bottle, if it is detected that part or all of the dilution liquid bottles are in the capped state, the sample needle is controlled to suck the dilution liquid from the specified dilution liquid bottle in the capped state.

[0082] As shown in Figure 7 In one embodiment, an anti-collision detection device is proposed, which is applied to a liquid transfer mechanism, the liquid transfer mechanism is fixed by a fixing block, and a signal change detection device is arranged between the liquid transfer mechanism and the fixing block, and the device comprises:

[0083] The acquisition module 702 is configured to determine a detection signal value according to a change value of the signal change detection device during the downward movement of the liquid transfer mechanism.

[0084] The judgment module 704 is configured to determine whether the liquid transfer mechanism encounters an obstacle during the downward movement according to the detection signal value and a preset standard signal value, the standard signal value being determined in advance based on a signal change value of the signal change detection device during the normal downward movement of the liquid transfer mechanism.

[0085] The control module 706 is configured to control the liquid transfer mechanism according to a preset strategy if the liquid transfer mechanism encounters an obstacle.

[0086] In one embodiment, the acquisition module 702 comprises:

[0087] The first acquisition unit is configured to collect an electrical signal change value of the signal change detection device during the downward movement of the liquid transfer mechanism by using a sensor, and determine the detection signal value according to the electrical signal change value.

[0088] Or,

[0089] The second acquisition unit is configured to collect the signal change value of the signal change detection device in the lowering process of the liquid transfer mechanism by using a sensor, and calculate a pressure change value according to the signal change value of the signal change detection device, and take the pressure change value as the detection signal value.

[0090] In one embodiment, the judging module 704 comprises:

[0091] The first determining unit is configured to determine that the liquid transfer mechanism encounters an obstacle if the detection signal value is greater than the standard signal value.

[0092] The second determining unit is configured to determine that the liquid transfer mechanism does not encounter an obstacle if the detection signal value is less than or equal to the standard signal value.

[0093] In one embodiment, the control module 706 comprises:

[0094] The first control unit is configured to control the liquid transfer mechanism to move upward or stop moving downward.

[0095] Or,

[0096] The second control unit is configured to control the liquid transfer mechanism to perform constant-pressure puncture according to the signal change value of the signal change detection device if the detection signal value is less than or equal to a preset signal value, the preset signal value being greater than the standard signal value.

[0097] It should be noted that the content involved in the embodiments of the present application is similar to the content described in the foregoing method embodiments, and the specific content can be referred to the content described in the foregoing method embodiments, which will not be repeated here.

[0098] The above anti-collision detection device determines the detection signal value according to the change value of the signal change detection device in the lowering process of the liquid transfer mechanism, judges whether the liquid transfer mechanism encounters an obstacle in the lowering process according to the detection signal value and a preset standard signal value, the standard signal value being determined in advance according to the signal change value of the signal change detection device in the normal lowering process of the liquid transfer mechanism, and controls the liquid transfer mechanism according to a preset strategy if the liquid transfer mechanism encounters an obstacle, so that it can be determined whether an obstacle is encountered, and the liquid transfer mechanism encountering an obstacle is controlled, thereby avoiding the liquid transfer mechanism from being damaged by colliding with the obstacle, and protecting the liquid transfer mechanism.

[0099] For example, Figure 8As shown, in one embodiment, a control device of a sample analyzer is provided, the sample analyzer comprising a first liquid transfer mechanism and a second liquid transfer mechanism, the first liquid transfer mechanism being fixed by a fixed block, and a signal change detection device being arranged between the first liquid transfer mechanism and the fixed block; the control device comprising:

[0100] a signal acquisition module 802 configured to determine a detection signal value according to a change value of the signal change detection device during a downward movement of the first liquid transfer mechanism from a current detection position;

[0101] a detection module 804 configured to determine a detection result according to whether the first liquid transfer mechanism encounters an obstacle during the downward movement according to the detection signal value and a preset standard signal value; the standard signal value being determined in advance based on a signal change value of the first liquid transfer mechanism during a normal downward movement;

[0102] a mechanism control module 806 configured to control the second liquid transfer mechanism according to the detection result of the current detection position.

[0103] In one embodiment, the signal acquisition module 802 comprises:

[0104] a first signal acquisition unit configured to collect an electrical signal change value of the signal change detection device during the downward movement of the first liquid transfer mechanism by using a sensor, and determine the detection signal value according to the electrical signal change value;

[0105] or,

[0106] a second signal acquisition unit configured to collect an electrical signal change value of the signal change detection device during the downward movement of the first liquid transfer mechanism by using a sensor, and calculate a pressure change value according to the electrical signal change value of the signal change detection device, and take the pressure change value as the detection signal value.

[0107] In one embodiment, the detection module 804 comprises:

[0108] a first detection unit configured to determine that the first liquid transfer mechanism encounters an obstacle if the detection signal value is greater than the standard signal value;

[0109] a second detection unit configured to determine that the first liquid transfer mechanism does not encounter an obstacle if the detection signal value is less than or equal to the standard signal value.

[0110] In one embodiment, the control device of the sample analyzer further comprises:

[0111] a recording module configured to record the detection result of the current detection position;

[0112] The first control module is configured to, if there is still an undetected detection position, take any one of the undetected detection positions as the current detection position, and return to execute the step of determining the detection signal value based on the change value of the signal change detection device in the process of moving downward from the current detection position by the first liquid transfer mechanism.

[0113] The second control module is configured to, if there is no undetected detection position, continue to execute the step of controlling the second liquid transfer mechanism based on the detection result of the current detection position.

[0114] In one embodiment, the control module 806 comprises:

[0115] A determination unit is configured to determine, based on the recorded detection results, a number of first target detection positions at which no obstacle is encountered.

[0116] A control unit is configured to, if the number of the first target detection positions is greater than a preset first value, control the second liquid transfer mechanism to move downward from the first target detection position and transfer liquid.

[0117] In one embodiment, the control device of the sample analyzer further comprises a locking module configured to, if the number of the first target detection positions is greater than a preset second value, determine a second target detection position at which an obstacle is encountered, and lock the second target detection position, the second value being greater than or equal to the first value.

[0118] In one embodiment, the control device of the sample analyzer further comprises a processing module configured to display an alarm information on a display interface, and display an elimination button corresponding to the alarm information, the alarm information containing the second target detection position, and the alarm information being used to prompt to remove the obstacle of the second target detection position.

[0119] It should be noted that the content involved in the embodiments of the present application is similar to the content described in the foregoing method embodiments, and the specific content can be referred to the content described in the foregoing method embodiments, which will not be repeated here.

[0120] The sample analyzer comprises a first liquid transfer mechanism and a second liquid transfer mechanism, the first liquid transfer mechanism is fixed through a fixed block, and a signal change detection device is arranged between the first liquid transfer mechanism and the fixed block, so that the change value of the signal change detection device in the process of the first liquid transfer mechanism moving downward from the current detection position can be obtained as a detection signal value; according to the detection signal value and a preset standard signal value, whether the first liquid transfer mechanism encounters an obstacle in the process of moving downward is judged, and a detection result is obtained; wherein the standard signal value is determined in advance according to the signal change value of the first liquid transfer mechanism in the normal moving downward process; the second liquid transfer mechanism is controlled according to the detection result of the current detection position, so that the detection of the obstacle can be realized by the first liquid transfer mechanism, and the control of the second liquid transfer mechanism is realized based on the detection result, without the need for the second liquid transfer mechanism to detect the obstacle, the liquid can be obtained through the first liquid transfer mechanism and the second liquid transfer mechanism, and the efficiency is improved.

[0121] Figure 9 An internal structure diagram of a computer device in an embodiment is shown. The computer device can be a terminal or a server. As shown in the figure, Figure 9 The computer device comprises a processor, a memory and a network interface connected through a system bus. The memory comprises a non-volatile storage medium and an internal memory. The non-volatile storage medium of the computer device stores an operating system, and can also store a computer program, which, when executed by the processor, can enable the processor to implement the anti-collision detection method or the control method of the sample analyzer. The internal memory can also store a computer program, which, when executed by the processor, can enable the processor to execute the anti-collision detection method or the control method of the sample analyzer. Those skilled in the art can understand that Figure 9 The structure shown in the figure is only a block diagram of part of the structure related to the scheme of the present application, and does not constitute a limitation on the computer device to which the scheme of the present application is applied. The specific computer device can comprise more or fewer components than those shown in the figure, or some components can be combined, or have a different component arrangement.

[0122] In one embodiment, a computer readable storage medium is provided, which stores a computer program, the computer program being executed by a processor to enable the processor to perform the following steps:

[0123] The detection signal value is determined according to the change value of the signal change detection device in the process of the liquid transfer mechanism moving downward;

[0124] determining whether the liquid transfer mechanism encounters an obstacle during the downward movement according to the detection signal value and a preset standard signal value, the standard signal value being determined in advance based on the signal change value of the signal change detection device during the normal downward movement of the first liquid transfer mechanism;

[0125] controlling the liquid transfer mechanism according to a preset strategy if the liquid transfer mechanism encounters an obstacle.

[0126] Alternatively, the processor is caused to perform the following steps:

[0127] determining a detection signal value according to the change value of the signal change detection device during the downward movement of the first liquid transfer mechanism from the current detection position;

[0128] determining whether the first liquid transfer mechanism encounters an obstacle during the downward movement according to the detection signal value and a preset standard signal value, the standard signal value being determined in advance based on the signal change value of the first liquid transfer mechanism during the normal downward movement;

[0129] controlling the second liquid transfer mechanism according to the detection result of the current detection position.

[0130] Those skilled in the art can understand that all or part of the processes in the above-mentioned embodiment methods can be completed by a computer program instructing related hardware. The program can be stored in a non-volatile computer readable storage medium, and when the program is executed, the processes of the above-mentioned embodiments can be included. In the embodiments provided in the present application, any reference to memory, storage, database or other medium can include non-volatile and / or volatile memory. Non-volatile memory can include read-only memory (ROM), programmable ROM (PROM), electrically programmable ROM (EPROM), electrically erasable programmable ROM (EEPROM) or flash memory. Volatile memory can include random access memory (RAM) or external cache memory. As an illustration but not limitation, RAM is available in various forms, such as static RAM (SRAM), dynamic RAM (DRAM), synchronous DRAM (SDRAM), double data rate SDRAM (DDR SDRAM), enhanced SDRAM (ESDRAM), synchronous link (Synchlink) DRAM (SLDRAM), memory bus (Rambus) direct RAM (RDRAM), direct memory bus dynamic RAM (DRDRAM), and memory bus dynamic RAM (RDRAM).

[0131] Any combination of the technical features in the above embodiments can be made, and for the sake of brevity, not all possible combinations are described above, however, as long as the combination of the technical features does not exist in contradiction, it shall be considered within the scope of the present disclosure.

[0132] The above embodiments only express several implementation manners of the present application, and the description is relatively specific and detailed, but it shall not be understood as a limitation on the patent scope of the present application. It shall be pointed out that, for ordinary skilled persons in the art, several modifications and improvements can be made without departing from the concept of the present application, and these shall be within the protection scope of the present application. Therefore, the protection scope of the patent of the present application shall be subject to the appended claims.

Claims

1. A control method of a sample analyzer characterized by, The sample analyzer comprises a first liquid transfer mechanism and a second liquid transfer mechanism, the first liquid transfer mechanism is fixed by a fixed block, and a signal change detection device is arranged between the first liquid transfer mechanism and the fixed block; The control method comprises: determining a detection signal value according to a change value of the signal change detection device in a process in which the first liquid transfer mechanism moves downward from a current detection position; judging whether the first liquid transfer mechanism encounters an obstacle in the moving downward process according to the detection signal value and a preset standard signal value, to obtain a detection result; the standard signal value is determined in advance based on a signal change value of the signal change detection device in a normal moving downward process of the first liquid transfer mechanism; controlling the second liquid transfer mechanism according to the detection result of the current detection position; The method further comprises: recording the detection result of the current detection position; if there is still an undetected detection position, taking any one of the undetected detection positions as the current detection position, and returning to the step of determining the detection signal value according to the change value of the signal change detection device in the process in which the first liquid transfer mechanism moves downward from the current detection position; if there is no undetected detection position, continuing to execute the step of controlling the second liquid transfer mechanism according to the detection result of the current detection position; The method further comprises: determining the number of first target detection positions with no obstacle encountered based on the recorded detection results; if the number of the first target detection positions is greater than a preset first value, controlling the second liquid transfer mechanism to move downward from the first target detection position and transfer liquid.

2. The method of claim 1, wherein, The method further comprises: collecting an electrical signal change value of the signal change detection device in the moving downward process of the first liquid transfer mechanism by using a sensor, and determining the detection signal value according to the electrical signal change value; or collecting an electrical signal change value of the signal change detection device in the moving downward process of the first liquid transfer mechanism by using a sensor, calculating a pressure value from the electrical signal change value of the signal change detection device, and taking the pressure value as the detection signal value.

3. The method of claim 2, wherein, The method further comprises: if the detection signal value is greater than the standard signal value, determining that the first liquid transfer mechanism encounters an obstacle; if the detection signal value is less than or equal to the standard signal value, determining that the first liquid transfer mechanism does not encounter an obstacle.

4. The method of claim 1, wherein, The method further comprises: if the number of the first target detection positions is greater than a preset second value, determining a second target detection position that encounters an obstacle, and locking the second target detection position.

5. The method of claim 4, wherein, The method further comprises: The display interface displays alarm information and a button for eliminating the alarm information, the alarm information including the second target detection position, and the alarm information prompting to remove the obstacle in the second target detection position.

6. The method of claim 5, wherein, The method further comprises: If a click operation on the button is detected, the first liquid transfer mechanism is controlled to move down from each second target detection position in turn to detect whether an obstacle is encountered; If no obstacle is encountered, the display of the alarm information and the button is canceled; If an obstacle is encountered, the alarm information is updated using the third target detection position where the obstacle is encountered, and the updated alarm information is displayed.

7. A control device of a sample analyzer characterized by comprising: The sample analyzer comprises a first liquid transfer mechanism and a second liquid transfer mechanism, the first liquid transfer mechanism being fixed by a fixed block, and a signal change detection device being arranged between the first liquid transfer mechanism and the fixed block; The control device comprises: a signal acquisition module configured to determine a detection signal value according to a change value of the signal change detection device during movement of the first liquid transfer mechanism from a current detection position; a detection module configured to determine whether an obstacle is encountered during movement of the first liquid transfer mechanism according to the detection signal value and a preset standard signal value, and obtain a detection result, the standard signal value being determined in advance based on signal change values during normal movement of the first liquid transfer mechanism; a mechanism control module configured to control the second liquid transfer mechanism according to the detection result of the current detection position; a recording module configured to record the detection result of the current detection position; a first control module configured to, if there are still undetected detection positions, take any one of the undetected detection positions as the current detection position, and return to execute the step of determining the detection signal value according to the change value of the signal change detection device during movement of the first liquid transfer mechanism from the current detection position; a second control module configured to, if there are no undetected detection positions, continue to execute the step of controlling the second liquid transfer mechanism according to the detection result of the current detection position; the mechanism control module specifically comprises: a determination unit configured to determine the number of first target detection positions where no obstacle is encountered based on the recorded detection results; a control unit configured to, if the number of first target detection positions is greater than a preset first value, control the second liquid transfer mechanism to move down from the first target detection position and transfer liquid.

8. A computer-readable storage medium storing a computer program, the computer program being executed by a processor to cause the processor to execute the steps of the method according to any one of claims 1 to 6.

Citation Information

Patent Citations

  • Pipetting system for an analyser

    EP2793031A1

  • Sample analysis apparatus and liquid absorption control method

    WO2020232605A1