A hollow structural plug spring coil assembly and push system

Abstract

The present application provides a hollow structure embolism spring ring assembly and pushing system, comprising a spring ring and a core member, the spring ring is coiled into a lumen along an axis, the core member is arranged in the lumen, the spring ring is a hollow structure made of a metal wire, a filter assembly is arranged on the spring ring to reduce the thrombus in an aneurysm from entering a blood vessel through the filter assembly. The spring ring is a hollow structure, so that the spring ring is lighter in mass, the softness is improved, the hardness is reduced and the compliance is enhanced, the ability of the implanted spring ring to conform to the shape of the aneurysm is improved, the spring ring is beneficial to enter the aneurysm, the risk of the implanted spring ring top breaking the aneurysm is reduced, and the implanted spring ring embolism artery is more dense.

Description

TECHNICAL FIELD

[0001] The present application belongs to the technical field of medical devices, and particularly relates to a hollow structure embolization coil assembly and a pushing system. BACKGROUND

[0002] The coil is an effective embolization device for treating various aneurysms, and is a mature and most widely used interventional treatment method for treating aneurysms. The existing coil structure includes a three-dimensional structure and a two-dimensional structure. In most cases, a specific three-dimensional structure needs to be matched with a specific two-dimensional structure to form a complete coil. The design purpose of the three-dimensional structure is to build a stable framework in the aneurysm cavity and provide support function at the aneurysm neck, and the design purpose of the two-dimensional structure is to uniformly fill the open space in the aneurysm, so as to obtain the effect of dense filling. The existing coil has high hardness, which is not conducive to conforming to the aneurysm wall, reduces the ability of the implanted coil to conform to the shape of the aneurysm, and on the other hand, the hard coil is difficult to embolize the aneurysm and reduces the filling rate of the aneurysm cavity.

[0003] Therefore, it is necessary to provide an improved technical solution for the above-mentioned deficiencies of the prior art. SUMMARY

[0004] The purpose of the present application is to overcome the deficiencies in the prior art, and to provide a hollow structure embolization coil assembly and a pushing system.

[0005] In order to achieve the above-mentioned purpose, the present application provides the following technical solutions:

[0006] A hollow structure embolization coil assembly for embolizing an aneurysm, comprising a coil and a core member, the coil is composed of a wire, the coil is wound into a lumen along an axis, the core member is arranged in the lumen, and the coil is a hollow structure.

[0007] Preferably, a filter assembly is arranged on the coil to separate the inner cavity of the coil from the outside through the filter assembly.

[0008] Preferably, the filter assembly comprises a first filter part arranged on the side wall of the coil.

[0009] The first filter part is a strip-shaped filter screen, the first filter part is located between any two turns of the wire of the coil, and is connected with the wire in correspondence to form the coil, and a plurality of first filter parts are uniformly distributed on the coil.

[0010] Preferably, the length of each first filter part is not less than the length of each turn of the wire of the coil.

[0011] Preferably, a first filter part is arranged between every three metal wires, and the first filter part is fixed to the corresponding metal wire by welding.

[0012] Preferably, the first filter part is a tapered port, and a plurality of the tapered ports are arranged between the metal wires forming the spring coil.

[0013] Preferably, the tapered ports are uniformly distributed along the spring coil, or spirally distributed along the metal wires forming the spring coil.

[0014] Preferably, the filter assembly further comprises a second filter part arranged at the end of the spring coil.

[0015] Preferably, the second filter part is a circular filter screen, and two circular filter screens are arranged at the proximal end and the distal end of the spring coil.

[0016] A hollow structure embolism spring coil pushing system, comprising any of the above-mentioned embolism spring coils, further comprising a positioning tube and an adjuster, the distal end of the positioning tube extends into an aneurysm, the adjuster is arranged at the proximal end of the positioning tube, and the spring coil is driven by the adjuster to extend into the aneurysm along the positioning tube.

[0017] Beneficial effects: The spring coil is of a hollow structure, so that the spring coil is lighter in mass, softer, lower in hardness, and higher in compliance, thereby improving the ability of the implanted spring coil to conform to the shape of the aneurysm, facilitating the spring coil to enter the aneurysm, reducing the risk of the implanted spring coil breaking the aneurysm, making the spring coil embolize the aneurysm more densely, and improving the filling rate of the aneurysm cavity.

[0018] The filter assembly is arranged on the spring coil, blood can enter the inside of the spring coil through the filter assembly, and a thrombus is formed in the spring coil, so that the thrombus does not flow out of the spring coil, the thrombus is fixed in the spring coil, the risk of the thrombus entering the blood vessel is reduced, and the healing of the aneurysm is accelerated. BRIEF DESCRIPTION OF DRAWINGS

[0019] The drawings accompanying the specification of the present application form a part thereof, serve to provide further understanding of the application, and together with the description of the application, explain the application. The detailed description of the application and its examples serve to explain the application, but do not constitute an improper limitation of the application. Among them:

[0020] Figure 1 A structure diagram of a pushing system in a specific embodiment provided by the present application;

[0021] Figure 2 For Figure 1 A zoomed-in schematic view;

[0022] Figure 3 A structure diagram of a spring coil when the first filter part is a strip-shaped filter screen in a specific embodiment provided by the present application;

[0023] Figure 4 Structure diagram of the spring ring when the first filter part is a conical filter tip in the specific embodiment provided by the present application;

[0024] Figure 5 Use diagram of the spring ring in the specific embodiment provided by the present application.

[0025] In the figure: 1, arterial blood vessels; 2, aneurysm; 3, spring ring; 4, microcatheter; 5, regulator; 31, first filter part; 32, metal wire; 33, second filter part; 34, lumen; 35, core member. DETAILED DESCRIPTION

[0026] The technical solutions in the embodiments of the present application will be described clearly and completely below. Obviously, the described embodiments are only a part of the embodiments of the present application, rather than all the embodiments of the present application. All other embodiments obtained by those of ordinary skill in the art based on the embodiments in the present application belong to the scope of protection of the present application.

[0027] In the description of the present application, the terms "longitudinal", "transverse", "upper", "lower", "front", "back", "left", "right", "vertical", "horizontal", "top", "bottom", and the like indicate the orientation or positional relationship shown in the drawings, and are only used to facilitate the description of the present application and do not require the present application to be constructed and operated in a particular orientation, and therefore cannot be understood as a limitation on the present application. The terms "connected", "connected" used in the present application should be understood broadly, for example, can be fixedly connected, can also be detachably connected; can be directly connected, can also be indirectly connected through an intermediate part. For those of ordinary skill in the art, the specific meaning of the above terms can be understood according to the specific circumstances.

[0028] The present application will be described in detail below with reference to the accompanying drawings and in combination with the embodiments. It should be noted that the embodiments in the present application and the features in the embodiments can be combined with each other without conflict.

[0029] In cardiovascular and cerebrovascular diseases, intracranial aneurysm is a high morbidity and mortality of cerebrovascular disease, and is the main cause of subarachnoid hemorrhage. The mortality of ruptured intracranial aneurysm is as high as 51%, and the disability rate of survivors is close to 50%. At present, there are two ways to treat intracranial aneurysm in clinical practice: one is craniotomy surgery, which clamps or ligates the aneurysm. The disadvantage is that the operation time is long, the patient is severely injured, and it is very difficult to use surgical treatment for aneurysms in special parts such as the internal carotid artery and the vertebral artery trunk. The second is endovascular treatment, which is minimally invasive, safe and effective, and has become the preferred clinical treatment plan for many medical experts. At present, the most commonly used method is to insert a coil into the aneurysm cavity under the guidance of X-ray, as shown in Figures 1-5 The hollow structure embolization coil provided by the present application is used for embolizing an aneurysm, and includes a coil and a delivery guide wire (not shown in the figure). The coil is delivered to the arterial blood vessel by the delivery guide wire. The coil is made of a wire 32 and is shaped by winding. Specifically, the coil assembly includes a coil and a core member 35. The coil is wound along the axis to form a lumen 34. The core member 35 is arranged in the lumen 34. The coil is a hollow structure made of a wire. A filter assembly is arranged on the coil. The filter assembly separates the inner cavity of the coil from the outside. The filter assembly reduces the risk of thrombus in the aneurysm entering the blood vessel. Blood can enter the inner part of the coil through the filter assembly during blood flow. If blood forms thrombus in the inner part of the coil and is filtered by the filter assembly, the thrombus cannot leave the coil, so the thrombus is firmly fixed in the inner part of the coil, reducing the risk of thrombus entering the blood vessel. Moreover, the embolization effect can even reduce the length of the coil used, which reduces the cost of the patient and accelerates the healing of the aneurysm.

[0030] In the present embodiment, the coil can only consist of a primary shape, such as a simple single helix. After the coil is inserted into the aneurysm, it naturally bends to form a heterogeneous three-dimensional structure under the force in the space inside the aneurysm. Of course, more preferably, the coil has a primary shape and a secondary shape. The primary shape is a conventional linear structure, such as a helical coil. The secondary shape is formed by the wire 32 extending from the distal end of the catheter or guide wire and then being released to deviate. The secondary shape can include complex three-dimensional shapes, such as spherical, cubic, and other space-filling shapes, such as irregular heterogeneous three-dimensional structures produced by winding the wire in a series of mobius loops.

[0031] In another embodiment, the filtering assembly can only include the first filter 31 arranged on the side wall of the spring coil 3, the first filter being arranged between any two adjacent metal wires 32 of the side wall of the spring coil 3 to form a filter on the side wall, so that the blood passes through the first filter and enters the spring coil 3 and the thrombus is blocked in the spring coil 3; the filtering assembly can also only include the second filter 33 arranged on the end of the spring coil 3 to form a filter on the end, so that the blood passes through the second filter and enters the spring coil 3 and the thrombus is blocked in the spring coil 3; preferably, the first filter 31 arranged on the side wall of the spring coil 3 and the second filter 33 arranged on the end of the spring coil 3 are both provided, in which case the blood flow is stronger and the possibility of thrombus formation is reduced.

[0032] In an optional embodiment, when the filtering assembly is the first filter, the first filter 31 is a strip-shaped filter screen, the first filter 31 is located between any two adjacent metal wires 32 of the side wall of the spring coil 3 and is connected with the metal wires 32 to form the spring coil 3, a plurality of first filters 31 are uniformly distributed on the spring coil 3, the first filter 31 is fixedly connected between the two adjacent metal wires 32, the shape of the first filter 31 is adapted to the gap between the two adjacent metal wires 32 formed by accommodating the first filter 31, and the first filter 31 is connected with the metal wires 32 to form the spring coil 3, so that the spring coil 3 has a complete outer wall, thereby avoiding escaping from the gap. More preferably, the length of each first filter 31 is not less than the length of each metal wire 32 of the spring coil 3, so that a complete filter is formed in the circumferential direction of the spring coil 3, so as to ensure 360° no dead angle filtering of the blood, improve the filtering effect and the blood passing property, and the plurality of first filters 31 are uniformly distributed in the extension direction of the spring coil 3, so as to ensure good blood passing property in the extension direction of the spring coil 3, and further, one first filter 31 is arranged between every three metal wires 32, and the first filter 31 is fixedly connected with the corresponding metal wires 32 by welding, which does not damage the flexibility of the spring coil 3 and can well guarantee the filtering requirement.

[0033] In another optional embodiment, the first filter 31 can also be a tapered port, a plurality of tapered ports being arranged at intervals between a plurality of groups of adjacent two metal wires 32 forming the side wall of the spring coil 3. Specifically, the tapered port is an independent tapered shell, the tapered port is fixedly connected between the adjacent two metal wires 32 by welding, the tapered port is arranged at a middle position of the spring coil 3, the outer diameter of the tapered port is greater than the inner diameter, the ratio of the outer diameter to the inner diameter is 3:1, and the tapered port is also arranged according to the number of turns of the spring coil 3, one tapered port being arranged every three turns, the tapered port being directly arranged on the spring coil 3 without the need for connection mode and material selection. Preferably, the end face of the larger end of the tapered port is adapted to the outer wall of the spring coil 3 and does not protrude from the outer wall of the spring coil 3 after connection, thereby sequentially ensuring smoothness in the penetration process and not damaging the blood vessel.

[0034] In the embodiment, the tapered openings are evenly distributed along the length of the spring coil 3, so that blood can pass through the entire length of the spring coil 3, or the tapered openings are helically distributed along the wire 32 forming the spring coil 3, so that blood can pass through the entire circumference of the spring coil 3. The wire 32 between any two adjacent filters has three turns, which does not damage the flexibility of the spring coil 3 and can well guarantee the filtering requirement.

[0035] In the embodiment, the tapered openings and the strip-shaped filter screen can be provided simultaneously or only one of them is provided. When both are provided, they are arranged alternately.

[0036] In an alternative embodiment, the filtering assembly is a second filter part, and the second filter part 33 is a circular filter screen. The second filter part 33 is provided at the proximal end and / or the distal end of the spring coil 3. Preferably, two second filter parts 33 are provided at the two ends of the spring coil 3 respectively. The two circular filter screens are located at the distal end and the proximal end of the spring coil 3 respectively. The connection between the circular filter screen and the spring coil 3 is in the form of a clamp, adhesion, welding, screw knob connection or jack connection, and the welding is preferred.

[0037] In the embodiment, whether the filter screen is a circular filter screen or a strip-shaped filter screen, the filter screen is preferably made of a biocompatible metal or metal alloy wire which does not adversely react with tissues and fluids in the human body. The wire 32 can be circular, square, oval, triangular or another shape. In some embodiments, the wire 32 generally has a diameter of about 0.025 to about 0.09 mm, about 0.03 to about 0.08 mm, about 0.04 to about 0.06 mm. In some particular embodiments, the diameter of the wire 32 is 0.05 mm.

[0038] In the embodiment, the filtering assembly is made of a metal or alloy material, and the specific material is made of a material which can be heat-cured at a temperature of about 650°C. The metal or alloy should be radiopaque, so that the positioning and location of the implant in the body can be monitored by radioactivity technology. Preferably, suitable metals include but are not limited to noble metals such as platinum group metals, which include platinum, palladium, rhodium and rhenium, as well as iridium, gold, silver, tungsten and tantalum, and alloys of these metals with each other. Other metals include super-elastic metals such as “Nitinol” and the like.

[0039] The present application also provides a hollow structure embolism spring coil pushing system, referring to Figure 1 , which comprises any of the above spring coils 3, and further comprises a positioning tube and an adjuster 5. The positioning tube is a microcatheter 4, which is used to extend into a blood vessel. The adjuster 5 is provided at the proximal end of the positioning tube. The distal end of the positioning tube extends into an aneurysm. The adjuster is provided at the proximal end of the positioning tube. The spring coil is driven along the positioning tube into the aneurysm through the adjuster. The spring coil 3 can also be used with the positioning device for conventional spring coils 3, such as Figure 5, using the spring coil 3 wire guide through the guide tube under the guidance of the micro guide wire through the arterial blood vessels 1, and then the head end of the guide tube is placed into the aneurysm 2 cavity, and the spring coil 3 is extended through the guide tube distal end and placed into the aneurysm 2 cavity. When the spring coil 3 is successively extended from the guide tube into the aneurysm 2 cavity, the soft spring coil 3 fills the aneurysm 2 cavity, and forms an adaptive shape according to the shape of the aneurysm cavity. The spring coil 3 provided by the present application has better adaptability and better fills the aneurysm 2 cavity, and the filling is stopped until the spring coil 3 fills the aneurysm 2 cavity. In this embodiment, the implant can be placed into the body by many methods, including but not limited to chemical separation, thermal separation, and other types of mechanical separation. In the case of using a chemical separation mechanism, a dissolvable separation section is included between the locator and the spring coil 3 or at the distal end of the locator. The dissolvable separation section is dissolved, softened, swelled, degraded, or otherwise changed by injecting a biocompatible chemical through the micro catheter 4. Some embodiments of the chemical separation system include a dissolvable separation section, such as a polymer section dissolved with dimethyl sulfoxide, a nylon section dissolved with a fluorinated hydrocarbon, or a section dissolved with a saline solution or any of the other biocompatible solvents discussed above. The spring coil 3 of the present application can also be configured to be thermally separated from the locator, heat is applied to allow the engagement portion to be separated from the positioning device and to move distally into the catheter lumen 34.

[0040] The above description is only the preferred embodiment of the present application, and is not intended to limit the present application. Any modification, equivalent replacement, improvement, etc. made within the spirit and principle of the present application is within the scope of the claims of the present application.

Claims

1. A hollow structural embolization coil assembly for embolizing an aneurysm, comprising a coil and a core member, the coil being constructed of wire, the coil being coiled along an axis into a lumen, the core member being disposed within the lumen, characterized in that, The spring ring is a hollow structure; a filter assembly is arranged on the spring ring to separate the spring ring cavity from the outside through the filter assembly; the filter assembly comprises a first filter part arranged on the side wall of the spring ring; The first filter part is a strip-shaped filter screen, the first filter part is located between any two turns of the metal wires of the spring ring and is connected with the metal wires correspondingly to form the spring ring, and a plurality of the first filter parts are uniformly distributed on the spring ring.

2. The hollow structural plug spring coil assembly of claim 1, wherein, The length of each first filter part is not less than the length of each turn of the metal wires of the spring ring.

3. The hollow structural plug spring coil assembly of claim 2, wherein, One turn of the first filter part is arranged between every three turns of the metal wires, and the first filter part is fixed with the corresponding metal wire by welding.

4. The hollow structural plug spring coil assembly of claim 2, wherein, The first filter part is a conical port, and a plurality of the conical ports are arranged between the metal wires forming the spring ring.

5. The hollow structural plug spring coil assembly of claim 4, wherein, The conical ports are uniformly distributed along the direction of the spring ring, or are spirally distributed along the metal wires forming the spring ring.

6. The hollow structural plug spring coil assembly of claim 2, wherein, The filter assembly further comprises a second filter part arranged at the end of the spring ring.

7. The hollow structural plug spring coil assembly of claim 6, wherein, The second filter part is a circular filter screen, and two circular filter screens are arranged correspondingly at the second filter part and at the proximal end and the distal end of the spring ring.

8. A hollow structural plug spring coil assembly push system comprising the plug spring coil of any one of claims 1-7, wherein, Further comprising a positioning tube and an adjuster, the distal end of the positioning tube extends into the aneurysm, the adjuster is arranged at the proximal end of the positioning tube, and the spring ring is driven along the positioning tube into the aneurysm through the adjuster.

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