A radiofrequency ablation handle and radiofrequency ablation device for reducing intraocular pressure or treating glaucoma

Abstract

The present invention discloses a radiofrequency ablation handle, comprising a shell and a radiofrequency ablation electrode installed in the shell, wherein the front end of the radiofrequency ablation electrode extends out of the shell; the radiofrequency ablation electrode is cylindrical as a whole, comprising an electrode positive pole, an insulating sleeve and an electrode negative pole; after the radiofrequency ablation electrode is energized, an ablation band is generated between the electrode positive pole and the electrode negative pole, and the ablation band is used to act on the ciliary body to reduce the production of aqueous humor; the shell is also connected to a pushing mechanism, which is fixedly connected to the electrode positive pole, and the electrode negative pole is fixedly connected to the shell, and the pushing mechanism can drive the electrode positive pole to move back and forth, and adjust the distance between the front end of the electrode positive pole and the front end of the electrode negative pole. In the present invention, the pushing mechanism accurately adjusts the depth of the radiofrequency ablation electrode inserted into the eye to adapt to the eyeballs of different patients and achieve the purpose of precise ablation. The present invention also provides a radiofrequency ablation device, which is easy to operate and use.

Description

Technical Field

[0001] The present invention relates to the technical field of medical equipment, and in particular to a radiofrequency ablation handle and a radiofrequency ablation device for reducing intraocular pressure or treating glaucoma. Background Art

[0002] Glaucoma is a group of diseases characterized by optic disc atrophy and depression, visual field defects and decreased vision. Pathologically increased intraocular pressure and insufficient blood supply to the optic nerve are the primary risk factors for its onset. The optic nerve's tolerance to pressure damage is also related to the occurrence and development of glaucoma.

[0003] Aqueous humor is secreted by the ciliary epithelium on the inner surface of the ciliary body and enters the posterior chamber. It then flows through the lens and returns to the anterior chamber through the fenestration. Aqueous humor passively exits the anterior chamber angle via two main pathways: the first is through the trabecular meshwork, passing through the inner wall of Schlemms' canal to reach the lumen, then flowing into the collecting ducts, aqueous veins, and episcleral venous circulation. The second pathway is through the iris root, the uveal plexus, and the anterior surface of the ciliary muscle, through the interfascicular connective tissue and the suprachoroidal space, and out through the sclera. Obstruction of any link in the aqueous humor circulation pathway can lead to pathological changes caused by elevated intraocular pressure, but some patients also present with normal-tension glaucoma.

[0004] Intraocular pressure (IOP), also known as intraocular pressure, is the pressure exerted by the eye's contents on the inner wall of the eye. High IOP is an independent risk factor for glaucoma, leading to further damage to the optic nerve. Controlling IOP is an economical approach. In developing countries, surgical treatment is a preferred treatment option for glaucoma.

[0005] Simply put, the most important means of treating glaucoma is to lower intraocular pressure. There are two main ways to lower intraocular pressure: one is to increase the drainage of aqueous humor in the eye; the other is to reduce the production of aqueous humor in the eye.

[0006] There are many types of surgical treatments for glaucoma, such as laser therapy, trabeculectomy, drainage devices, and MIGS.

[0007] The above-mentioned surgical procedures or equipment all have certain limitations. Common laser treatments include trabeculectomy and laser cyclophotocoagulation. Trabeculectomy means that when the laser acts on the trabecular meshwork, the trabecular meshwork contracts locally, causing the adjacent trabecular meshwork to stretch, increasing the cavities and making the aqueous humor drainage circuit smoother. However, this surgery may only be effective for a limited period of time (a few years).

[0008] Laser cyclophotocoagulation involves applying a laser to the ciliary body, killing some of the tissue and reducing aqueous humor production. However, lasers can be irritating to the eye, and controlling the area of ​​effect can be difficult. In most cases, this procedure is reserved for patients with advanced glaucoma whose intraocular pressure remains elevated despite conventional medical and / or multiple surgical treatments.

[0009] When using a drainage device to treat glaucoma, a large incision needs to be made in the eye during the implantation process.

[0010] MIGS (Minimally Invasive Glaucoma Surgery) is a minimally invasive glaucoma surgery (MIGS). Common MIGS methods include anterior chamber-trabecular MIGS drainage and filtering bleb MIGS drainage. Anterior chamber-trabecular MIGS drainage involves using a drainage tube or drainage pin to penetrate the trabecular meshwork, connecting the anterior chamber and the Schlemms' canal. Under the influence of anterior chamber pressure, aqueous humor is directed through the drainage device into the Schlemms' canal. Aqueous humor in the Schlemms' canal then circulates through the collecting duct and episcleral veins. This process reduces aqueous humor in the anterior chamber and lowers intraocular pressure. However, this drainage method has limited antihypertensive effects and is suitable for treating patients with early-stage or intermediate-stage glaucoma. Furthermore, some patients experience blockage or adhesion of the Schlemms' canal. In these cases, connecting the anterior chamber and the trabecular meshwork may not effectively lower intraocular pressure.

[0011] MIGS drainage involves surgically or by other means separating the conjunctiva or sclera to create a bleb space. A drainage tube is then passed through the sclera to penetrate the trabecular meshwork, connecting the anterior chamber and the bleb. Under the influence of anterior chamber pressure, aqueous humor is directed through the tube into the bleb space, where it is absorbed by the sclera, completing the aqueous humor circulation. This process reduces the amount of aqueous humor in the anterior chamber and lowers intraocular pressure. The effectiveness of this drainage method is directly related to the morphology of the bleb. The sclera and conjunctiva have strong regenerative abilities, and surgical creation of a bleb carries the risk of scarring, which reduces drainage effectiveness. Furthermore, the bleb's location on the ocular surface can affect the patient's appearance, leading some patients to resist this procedure.

[0012] Prior art ablation can also treat glaucoma. One approach involves using ablation electrodes to destroy the aqueous humor within the ciliary body, thereby reducing aqueous humor production and lowering intraocular pressure, ultimately treating glaucoma. However, due to varying physiological conditions, the depth of the ciliary body, sclera, and conjunctiva varies from patient to patient, making it difficult to precisely control and adjust the depth of penetration of ablation electrodes into the patient's eye.

[0013] Furthermore, in the present invention, the structures inside the eyeball are explained as follows:

[0014] Ciliary body: Located in the middle part of the uveal tract, about 6mm thick, it is the main organ for secreting aqueous humor in the eye.

[0015] Conjunctiva: The part of the eye that lies inside the eyelid and covers the sclera (the white of the eye).

[0016] Sclera: commonly known as the white of the eye, it is a milky white, opaque fibrous membrane inside the eyeball, which belongs to the fibrous membrane of the eyeball.

[0017] Aqueous humor: The anterior chamber is filled with a colorless fluid called aqueous humor. Summary of the Invention

[0018] The present invention provides a radiofrequency ablation handle and a radiofrequency ablation device for reducing intraocular pressure or treating glaucoma, which solve the problem that the depth of radiofrequency ablation electrodes penetrating into the eye cannot be adjusted.

[0019] In order to solve the above technical problems, a technical solution adopted by the present invention is to provide a radiofrequency ablation handle, comprising a shell and a radiofrequency ablation electrode installed in the shell, the front end of the radiofrequency ablation electrode extending out of the shell; the radiofrequency ablation electrode is columnar as a whole, comprising an electrode positive pole located in the center, an insulating sleeve arranged around the outer periphery of the electrode positive pole, and an electrode negative pole arranged around the outer periphery of the insulating sleeve; the electrode positive pole, the insulating sleeve, and the electrode negative pole are coaxial, and the distance between the front end of the electrode positive pole and the front end of the electrode negative pole is the depth of the radiofrequency ablation electrode penetrating into the eye, and the front end of the electrode negative pole stays outside the eyeball; after the radiofrequency ablation electrode is energized, an ablation zone is generated between the electrode positive pole and the electrode negative pole, and the ablation zone is used to act on the ciliary body to reduce the production of aqueous humor; the shell is also connected to a pushing mechanism, the pushing mechanism is fixedly connected to the electrode positive pole, and the electrode negative pole is fixedly connected to the shell, and the pushing mechanism can drive the electrode positive pole to move back and forth to adjust the distance between the front end of the electrode positive pole and the front end of the electrode negative pole.

[0020] Preferably, the pushing mechanism includes a rotating component, a pushing slider and an elastic component; the rotating component is at least partially exposed outside the shell, and is connected to the pushing slider inside the shell through a pushing adjusting body; the pushing adjusting body rotates coaxially with the rotating component, and a plurality of pushing adjusting surfaces are provided along the circumferential ring of the pushing adjusting body, and each virtual line between the pushing adjusting surface and the central axis of the pushing adjusting body corresponds to an adjustment value; the pushing slider is slidably arranged inside the shell, the front end of the pushing slider is fixedly connected to the tail of the positive electrode, and the rear end of the pushing slider contacts the pushing adjusting surface; the elastic component is arranged between the front end of the pushing slider and the inner wall of the shell, and has an elastic force that pushes the pushing slider to slide backward.

[0021] Preferably, the elastic component is a reset spring, which is sleeved on the periphery of the negative electrode, with one end abutting against the front end of the pushing slider and the other end abutting against the inner wall of the shell.

[0022] Preferably, the push adjustment body is columnar, and a mounting hole for the push adjustment body to pass through is provided on the side wall of the shell; a plurality of protruding push adjustment parts are provided along the circumferential ring of the push adjustment body, each of the push adjustment surfaces corresponds to one push adjustment part, and the push adjustment surface is provided on the outer surface of the push adjustment part.

[0023] Preferably, the push regulating body is a hollow structure, and the push regulating body has a hollow rotating hole. A positioning shaft adapted to the rotating hole is further provided in the shell, and the positioning shaft is inserted into the rotating hole.

[0024] Preferably, a positioning slot is formed between two adjacent push adjustment parts, and the edge of the mounting hole is also provided with a protruding positioning block that is adapted to the positioning slot, so that during the rotation of the push adjustment body, the positioning block can be engaged in different positioning slots.

[0025] Preferably, a rotation adjustment hole is provided on the side wall of the shell, and a plurality of adjustment deformation holes are provided along the circumference of the rotation adjustment hole, and the portion between the mounting hole and the adjustment deformation holes constitutes a deformation portion.

[0026] Preferably, the push adjustment portion is further provided with a blocking portion for preventing the push adjustment body from separating from the housing.

[0027] Preferably, the rotating component is an adjusting knob, and the plurality of adjustment values ​​are arranged on a side wall of the adjusting knob along the circumference of the adjusting knob.

[0028] The present invention also provides a radiofrequency ablation device for reducing intraocular pressure or treating glaucoma, comprising the radiofrequency ablation handle described above, wherein the radiofrequency ablation handle is electrically connected to an ablation host.

[0029] The beneficial effects of the present invention are as follows: the present invention discloses a radiofrequency ablation handle for reducing intraocular pressure or treating glaucoma, comprising a shell and a radiofrequency ablation electrode installed in the shell, the front end of the radiofrequency ablation electrode extending out of the shell; the radiofrequency ablation electrode is cylindrical as a whole, comprising an electrode positive pole, an insulating sleeve and an electrode negative pole; after the radiofrequency ablation electrode is energized, an ablation band is generated between the electrode positive pole and the electrode negative pole, and the ablation band is used to act on the ciliary body to reduce the production of aqueous humor; the shell is also connected to a pushing mechanism, the pushing mechanism is fixedly connected to the electrode positive pole, and the electrode negative pole is fixedly connected to the shell, and the pushing mechanism can drive the electrode positive pole to move back and forth, and adjust the distance between the front end of the electrode positive pole and the front end of the electrode negative pole. In the present invention, the pushing mechanism accurately adjusts the depth of the radiofrequency ablation electrode inserted into the eye to adapt to the eyeballs of different patients and achieve the purpose of precise ablation. The present invention also provides a radiofrequency ablation device for reducing intraocular pressure or treating glaucoma, which is easy to operate and use. BRIEF DESCRIPTION OF THE DRAWINGS

[0030] Figure 1 is an overall schematic diagram of an embodiment of a radiofrequency ablation electrode in a radiofrequency ablation handle for reducing intraocular pressure or treating glaucoma according to the present invention;

[0031] Figure 2 is an exploded schematic diagram of an embodiment of a radiofrequency ablation electrode in a radiofrequency ablation handle for reducing intraocular pressure or treating glaucoma according to the present invention;

[0032] Figure 3 is an overall schematic diagram of another embodiment of a radiofrequency ablation electrode in a radiofrequency ablation handle for reducing intraocular pressure or treating glaucoma according to the present invention;

[0033] Figure 4 is an exploded schematic diagram of another embodiment of a radiofrequency ablation electrode in a radiofrequency ablation handle for reducing intraocular pressure or treating glaucoma according to the present invention;

[0034] Figure 5 is an overall schematic diagram of a radiofrequency ablation handle for reducing intraocular pressure or treating glaucoma according to the present invention;

[0035] Figure 6 is an exploded schematic diagram of a radiofrequency ablation handle for reducing intraocular pressure or treating glaucoma according to the present invention;

[0036] Figure 7 is a schematic diagram of a first shell in a radiofrequency ablation handle for reducing intraocular pressure or treating glaucoma according to the present invention;

[0037] Figure 8 is a schematic diagram of a second shell in a radiofrequency ablation handle for reducing intraocular pressure or treating glaucoma according to the present invention;

[0038] Figure 9 It is a three-dimensional schematic diagram of a push adjustment body in a radiofrequency ablation handle for reducing intraocular pressure or treating glaucoma according to the present invention;

[0039] Figure 10 It is a front view schematic diagram of a push adjustment body in a radiofrequency ablation handle for reducing intraocular pressure or treating glaucoma according to the present invention;

[0040] Figure 11 This is a schematic diagram of a push adjustment portion in a radiofrequency ablation handle for reducing intraocular pressure or treating glaucoma according to the present invention;

[0041] Figure 12 It is a side view of a push adjustment body in a radiofrequency ablation handle for reducing intraocular pressure or treating glaucoma according to the present invention;

[0042] Figure 13 is a schematic diagram of a rotating component in a radiofrequency ablation handle for reducing intraocular pressure or treating glaucoma according to the present invention;

[0043] Figure 14 This is a schematic diagram of a push adjustment body installed in a housing in a radiofrequency ablation handle for reducing intraocular pressure or treating glaucoma according to the present invention;

[0044] Figure 15 is a schematic diagram of a push slider in a radiofrequency ablation handle for reducing intraocular pressure or treating glaucoma according to the present invention;

[0045] Figure 16 This is a schematic diagram of a push tube in a radiofrequency ablation handle for reducing intraocular pressure or treating glaucoma according to the present invention;

[0046] Figure 17 It is a partial cross-sectional view of a radiofrequency ablation handle for reducing intraocular pressure or treating glaucoma according to the present invention. DETAILED DESCRIPTION

[0047] To facilitate understanding of the present invention, the present invention will be described in more detail below with reference to the accompanying drawings and specific embodiments. Preferred embodiments of the present invention are shown in the accompanying drawings. However, the present invention can be implemented in many different forms and is not limited to the embodiments described in this specification. Rather, these embodiments are provided to provide a more thorough and comprehensive understanding of the disclosure of the present invention.

[0048] It should be noted that, unless otherwise defined, all technical and scientific terms used in this specification have the same meanings as those commonly understood by those skilled in the art to which this invention pertains. The terms used in this specification are intended solely for the purpose of describing specific embodiments and are not intended to limit the invention. The term "and / or" as used in this specification includes any and all combinations of one or more of the associated listed items.

[0049] like Figures 1 to 17 As shown, the radiofrequency ablation handle for reducing intraocular pressure or treating glaucoma includes a shell 1 and a radiofrequency ablation electrode 2 installed in the shell 1. The front end of the radiofrequency ablation electrode 2 extends out of the shell 1 to facilitate insertion into the eye.

[0050] Combine Figure 1 and Figure 2 , as the first embodiment of the radiofrequency ablation electrode 2 in the present invention.

[0051] The RF ablation electrode 2 is generally cylindrical and includes a centrally located positive electrode 201, an insulating sleeve 202 surrounding the positive electrode 201, and a negative electrode 203 surrounding the insulating sleeve 202. The positive electrode 201, insulating sleeve 202, and negative electrode 203 are coaxial. When the RF ablation electrode 2 is energized, an ablation zone is generated between the positive electrode 201 and the negative electrode 203. This ablation zone acts on the ciliary body to reduce aqueous humor production. For eyes with shallow anterior chambers, ablation with the RF ablation electrode 2 can cause the ciliary body to contract, increasing the gap between the lens and the ciliary RF ablation electrode 2, reducing ciliary block, lowering the trans-lens pressure gradient, and deepening the anterior chamber.

[0052] The radiofrequency ablation electrode 2 in the present invention can easily enter the narrow space of the eye to ablate the ciliary body, producing a controllable small ablation area; the ablation zone is concentrated between the electrode positive pole 201 and the electrode negative pole 203. The insertion position of the radiofrequency ablation electrode 2 determines the ablation position, which can be the tissue surface or a specific position inside the tissue.

[0053] Furthermore, the positive electrode 201 has excellent biocompatibility and good electrical conductivity. The positive electrode 201 can be made of stainless steel, such as 2Cr13, 1Cr13, 1Cr18Ni9, SUS304(L), SUS316(L), or SUS430; titanium alloys, such as TC4; or conductive metal materials, such as pure titanium, tungsten steel, pure tungsten, tungsten carbide, platinum, or platinum-iridium alloys.

[0054] Preferably, the positive electrode 201 is cylindrical as a whole, and the length of the positive electrode 201 is 3 mm to 50 mm, and the diameter is 0.1 mm to 1 mm.

[0055] Preferably, in order to facilitate the insertion of the tissue, the front end of the electrode positive electrode 201 is processed into a first conical tip 2011. The first conical tip 2011 can be a cone, a triangular pyramid, a quadrangular pyramid or other conical shapes. Figure 1 In the embodiment, the first conical tip 2011 is conical. The first conical tip 2011 can be made into a sharp cone by grinding or heating, melting and drawing, so that the positive electrode 201 can easily pierce the eye and reach the target tissue during puncture.

[0056] Furthermore, the insulating sleeve 202 is a cylindrical sleeve as a whole, and has good biocompatibility and insulation. The material of the insulating sleeve can be Parylene / silicone / PTFE / ABS / PI / PET, or the insulating coating can be made by vapor deposition method, and the material of the insulating coating is Parylene.

[0057] Furthermore, the negative electrode 203 has excellent biocompatibility and good electrical conductivity. The negative electrode 203 can be made of stainless steel, such as 2Cr13, 1Cr13, 1Cr18Ni9, SUS304(L), SUS316(L), or SUS430; titanium alloys, such as TC4; or conductive metal materials, such as pure titanium, tungsten steel, pure tungsten, platinum, or platinum-iridium alloys.

[0058] The length of the negative electrode 203 is 3 mm to 50 mm, the inner diameter is 0.1 mm to 1.1 mm, and the outer diameter is 0.2 mm to 1.5 mm.

[0059] Furthermore, in the present invention, the length of the positive electrode 201 is greater than the length of the insulating sleeve 202 , and the length of the insulating sleeve 202 is greater than the length of the negative electrode 203 .

[0060] The insulating sleeve 202 extends from the tail of the first conical tip 2011 toward the tail of the electrode positive pole 201, and the tail of the insulating sleeve 202 does not overlap with the tail of the electrode positive pole 201, that is, the tail of the electrode positive pole 201 must be exposed; the tail of the electrode positive pole 201 must remain conductive and be used to be electrically connected to the RF positive pole signal cable; the tail of the electrode negative pole 203 is electrically connected to the RF negative pole signal cable.

[0061] Preferably, the insulating sleeve 202 is fixedly connected to the positive electrode 201. The insulating sleeve 202 can be directly sleeved onto the positive electrode 201 by interference fit; can also be sleeved onto the positive electrode 201 by gluing; or can be sleeved onto the positive electrode 201 and fixed to the positive electrode 201 by heat shrinking or other methods; or a parylene coating can be deposited on the positive electrode 201 by vapor deposition, and a shielding layer can be formed at the tip and tail of the positive electrode 201 before the coating is deposited, and the shielding layer can be removed after the coating is deposited; or, after the coating is deposited, the coating at the tip and tail of the positive electrode 201 can be stripped by grinding, scraping, or laser stripping to achieve the purpose of insulating the middle of the positive electrode 201 and conducting at both ends.

[0062] Furthermore, in the present invention, the first conical tip 2011 at the front end of the positive electrode 201 pierces the conjunctiva and sclera and enters the ciliary body; at the same time, due to the thin wall thickness of the insulating sleeve 202, the insulating sleeve 202 also enters the ciliary body; the wall thickness of the negative electrode 203 is relatively large, and it stays outside the eyeball and does not enter the eyeball; therefore, the process of the radiofrequency ablation electrode 2 piercing the human eye is smooth and labor-saving, without steps, and there is no jamming during the insertion process.

[0063] In addition, the first conical tip 2011 of the positive electrode 201 is a sharp point for discharge. The current density released by the first conical tip 2011 is extremely large, and the ablation site is concentrated at the position of the first conical tip 2011. Since the area of ​​the negative electrode 203 is also large, the current can be stably transmitted through the human eye tissue to the negative electrode 203 to form a loop. Therefore, the ablation effect of the radiofrequency ablation electrode 2 is also excellent.

[0064] In the present invention, the length between the tip of the first conical tip 2011 on the RF ablation electrode 2 and the front end of the electrode cathode 203 represents the penetration depth of the RF ablation electrode 2 into the eye. Due to varying physiological conditions, the thickness of the sclera, conjunctiva, and ciliary body varies across patients. From the perspective of ocular anatomy, the precise penetration depth of the RF ablation electrode 2 directly impacts the ablation location, significantly affecting the ultimate treatment outcome.

[0065] Preferably, the positive electrode 201 and the negative electrode 203 can slide relative to each other to adjust the depth of penetration into the eye to adapt to the eyeballs of different patients and achieve the purpose of precise ablation.

[0066] Furthermore, the positive electrode 201 and the negative electrode 203 can slide relative to each other, and because the positive electrode 201 and the insulating sleeve 202 are fixedly connected, the insulating sleeve 202 and the negative electrode 203 can slide relative to each other.

[0067] In the present invention, the distance between the front end of the electrode positive pole 201 and the front end of the electrode negative pole 203 is adjusted by the pushing mechanism 3 in the radiofrequency ablation handle, that is, the depth of the electrode positive pole 201 penetrating into the eye can be adjusted by the pushing mechanism 3. The adjustment principle is described below.

[0068] Further, combined Figures 3 and 4 In the present invention, the second embodiment of the radiofrequency ablation electrode 2 is provided. Based on the first radiofrequency ablation electrode 2, the front end of the negative electrode 203 is further provided with a negative electrode disk 2031, and the shape of the negative electrode disk 2031 can be circular, triangular, square, etc.

[0069] Preferably, the negative electrode disk 2031 is in the shape of a flat disc. Of course, it can also be a patterned disc, a hollow disc, or a special-shaped disc. The negative electrode disk 2031 can increase the return area of ​​the current, so that the ablation location is concentrated at the tip of the positive electrode 201. Secondly, the negative electrode disk 2031 has a large cross-section and can also serve as a limiter to ensure that the negative electrode 203 does not penetrate the eyeball during the operation, preventing the radiofrequency ablation electrode 2 from piercing the eyeball.

[0070] Further, combined Figures 5 to 17 In the present invention, the radiofrequency ablation handle includes a housing 1, which is in the shape of a straight rod, or can be large in the middle and small at both ends, or large at both ends and small in the middle, suitable for single-handed operation.

[0071] The material of the housing 1 can be ABS, POM, PEEK, PVC, PET, nylon, polymer materials, modified engineering plastics, zinc alloy, aluminum alloy, magnesium-aluminum alloy, stainless steel, copper, iron, etc.

[0072] Further, such as Figures 6 to 8 The housing 1 includes a first housing 101 and a second housing 102 . A tapered portion 1017 is provided at the front end of the first housing 101 , and the front end of the radiofrequency ablation electrode 2 passes through the tapered portion 1017 .

[0073] The first shell 101 and the second shell 102 are detachably connected, and the detachable connection can be achieved by means of a snap connection, a threaded connection, or the like.

[0074] Preferably, the first shell 101 and the second shell 102 may also be fixedly connected, for example, by gluing, ultrasonic welding, laser welding or other fixing methods.

[0075] Preferably, a first positioning post 1015 is provided on the inner wall of the first housing 101, and a second positioning post 1023 is correspondingly provided on the inner wall of the second housing 102. The second positioning post 1023 is further provided with a positioning hole 1024, so that the first positioning post 1015 can be inserted into the positioning hole 1023. In this way, the first housing 101 and the second housing 102 can be pre-positioned when connected.

[0076] Preferably, the housing 1 is further connected to a stress relief tube 11, the front end of which is snap-fitted into the interior of the housing 1. A limit block 14 is provided on either side of the front end of the stress relief tube 11. The rear ends of both the first housing 101 and the second housing 102 are provided with mounting slots 12, each of which contains a slot 13 corresponding to the limit block 14. The front end of the stress relief tube 11 can be installed in one of the mounting slots 12, with the limit block 14 snapping into the slot 13. Once the first housing 101 and the second housing 102 are connected, the stress relief tube 11 is simultaneously secured.

[0077] The stress release tube 11 plays a role in protecting the RF positive signal cable and the RF negative signal cable, and will not cause the RF positive signal cable and the RF negative signal cable to break due to bending the stress release tube 11; the RF positive signal cable and the RF negative signal cable are used to electrically connect the electrode positive electrode 201 and the electrode negative electrode 203 respectively.

[0078] Preferably, a tightening clamp 1016 is further provided in the first shell 101 . There are multiple tightening clamps 1016 , which are provided in the middle part of the inner wall of the first shell 101 and are used to bind the RF positive signal cable and the RF negative signal cable.

[0079] Furthermore, the shell 1 is also connected to a pushing mechanism 3, which is fixedly connected to the electrode positive pole 201, and the electrode negative pole 203 is fixedly connected to the shell 1. The pushing mechanism 3 can drive the electrode positive pole 201 to move forward and backward, and adjust the distance between the front end of the electrode positive pole 201 and the front end of the electrode negative pole 203.

[0080] In the present invention, the distance between the front end of the positive electrode 201 and the front end of the negative electrode 203 is the depth of penetration of the positive electrode 201 into the eyeball. Since the negative electrode 203 is fixedly connected to the housing 1, specifically, the negative electrode 203 is fixedly connected to the first housing 101, the negative electrode 203 of the motor remains stationary relative to the positive electrode 201. Therefore, the depth of penetration of the positive electrode 201 into the eyeball can be adjusted by moving the positive electrode 201 back and forth via the pushing mechanism 3.

[0081] In the present invention, the pushing mechanism 3 includes a rotating component 4 , a pushing slider 5 and an elastic component 6 .

[0082] Rotating part 4: Combination Figures 9 to 14The rotating component 4 is at least partially exposed outside the housing 1 and is connected to the pushing slider 5 inside the housing 1 through the pushing regulating body 7. The pushing regulating body 7 is integrally connected to the rotating component 4 and can rotate coaxially with the rotating component 4.

[0083] Pushing slider 5: The pushing slider 5 is slidably arranged inside the shell 1 and can move along the front and rear directions of the shell 1; the front end of the pushing slider 5 is fixedly connected to the tail of the positive electrode 201, and the rear end of the pushing slider 5 is used to contact the pushing adjustment surface 71 on the pushing adjustment body 7; by rotating the pushing adjustment body 7 so that different pushing adjustment surfaces 71 contact the rear end of the pushing slider 5, the front and rear movement distance of the pushing slider 5 can be adjusted.

[0084] Specifically, a plurality of push adjustment surfaces 71 are provided along the circumferential ring of the push adjustment body 7, and the push adjustment surface 71 is used to contact the rear end of the push slider 5, and the virtual line between each push adjustment surface 71 and the central axis Z of the push adjustment body 7 corresponds to an adjustment value, respectively. The adjustment value reflects the penetration depth of the electrode positive electrode 201, that is, when the push adjustment surface 71 is used to contact the rear end of the push slider 5, the penetration depth of the electrode positive electrode 201 is the adjustment value.

[0085] Furthermore, the push regulating body 7 is columnar, and a plurality of protruding push regulating portions 72 are provided along the circumference of the push regulating body 7 . Each push regulating surface 71 corresponds to one push regulating portion 72 , and the push regulating surface 71 is provided on the outer surface of the push regulating portion 72 .

[0086] Preferably, the present invention has six push adjustment parts 72, but this is not limited to six and may also have three, four, or five. The six push adjustment parts 72 are respectively a first push adjustment part 721, a second push adjustment part 722, a third push adjustment part 723, a fourth push adjustment part 724, a fifth push adjustment part 725, and a sixth push adjustment part 726. The push adjustment surface 71 is correspondingly a first push adjustment surface 711, a second push adjustment surface 712, a third push adjustment surface 713, a fourth push adjustment surface 714, a fifth push adjustment surface 715, and a sixth push adjustment surface 716.

[0087] Among them, the virtual line between the first pushing adjustment surface 711 and the central axis Z of the pushing adjustment body 7 is the first virtual line S1, and the adjustment value corresponding to the first virtual line S1 is 1.3 mm, that is, when the first pushing adjustment surface 711 contacts the rear end of the pushing slider 5, the depth of the electrode positive pole 201 penetrating the eyeball is 1.3 mm.

[0088] The virtual line between the second pushing adjustment surface 712 and the central axis Z of the pushing adjustment body 7 is the second virtual line S2. The adjustment value corresponding to the second virtual line S2 is 1.4 mm, that is, when the second pushing adjustment surface 712 contacts the rear end of the pushing slider 5, the depth of the electrode positive pole 201 penetrating the eyeball is 1.4 mm.

[0089] The virtual line between the third pushing adjustment surface 713 and the central axis Z of the pushing adjustment body 7 is the third virtual line S3. The adjustment value corresponding to the third virtual line S3 is 1.5 mm, that is, when the third pushing adjustment surface 713 contacts the rear end of the pushing slider 5, the depth of the electrode positive pole 201 penetrating the eyeball is 1.5 mm.

[0090] The virtual line between the fourth pushing adjustment surface 714 and the central axis Z of the pushing adjustment body 7 is the fourth virtual line S4. The adjustment value corresponding to the fourth virtual line S4 is 1.6 mm, that is, when the fourth pushing adjustment surface 714 contacts the rear end of the pushing slider 5, the depth of the electrode positive pole 201 penetrating the eyeball is 1.6 mm.

[0091] The virtual line between the fifth pushing adjustment surface 715 and the central axis Z of the pushing adjustment body 7 is the fifth virtual line S5. The adjustment value corresponding to the fifth virtual line S5 is 1.7 mm, that is, when the fifth pushing adjustment surface 715 contacts the rear end of the pushing slider 5, the depth of the electrode positive pole 201 penetrating the eyeball is 1.6 mm.

[0092] The virtual line between the sixth pushing adjustment surface 716 and the central axis Z of the pushing adjustment body 7 is the sixth virtual line S6. The adjustment value corresponding to the sixth virtual line S6 is 1.8 mm, that is, when the sixth pushing adjustment surface 716 contacts the rear end of the pushing slider 5, the depth of the electrode positive pole 201 penetrating the eyeball is 1.8 mm.

[0093] Preferably, Figure 13 In the embodiment, rotating component 4 is an adjustment knob located on the side closest to the first housing 101 and completely exposed outside the first housing 101. The adjustment knob is circular in shape. Multiple adjustment values ​​(1.3mm, 1.4mm, 1.5mm, 1.6mm, 1.7mm, and 1.8mm) are arranged around the sidewall of the adjustment knob to facilitate the operator's observation of the penetration depth of the positive electrode 201 into the eyeball during adjustment.

[0094] Furthermore, a mounting hole 1011 for the push adjustment body 7 to pass through is provided on the side wall of the housing 1 , and the mounting hole 1011 is specifically provided on the first housing 101 .

[0095] Preferably, the push adjustment body 7 is also a hollow structure, that is, a hollow column; the push adjustment body 7 has a hollow rotating hole 74, and a positioning shaft 1021 adapted to the rotating hole 74 is also provided in the shell 1. The positioning shaft 1021 is provided on the second shell 102, and the positioning shaft 1021 is inserted into the rotating hole 74, so that the push adjustment body 7 can rotate around the positioning shaft 1021.

[0096] Furthermore, a positioning slot 73 is formed between two adjacent push-adjustment sections 72. The shape of the positioning slot 73 depends on the shape of the push-adjustment section 72. In the present invention, the push-adjustment section 72 has an isosceles trapezoidal cross-section, while the positioning slot 73 has a V-shape. The edge of the mounting hole 1011 is also provided with a protruding positioning block 1012 that matches the positioning slot 73. During the rotation of the push-adjustment body 7, the positioning block 1012 can be engaged with different positioning slots 73. This method requires the operator to use a certain amount of force to twist the rotating part 4, thereby causing the positioning block 1012 to engage from the current positioning slot 73 to the next positioning slot 73; that is, the damping of the push adjustment body 7 during the rotation process is increased to prevent the push adjustment body 7 from being easily twisted; correspondingly, precisely because the push adjustment body 7 will not be easily twisted, the push adjustment surface 71 on the push adjustment body 7 can be in close contact with the rear end of the push slider 5, and the push adjustment surface 71 will not change easily, which also ensures the accuracy and stability of the insertion depth of the electrode positive pole 201.

[0097] Further, in Figure 7 In the embodiment, a rotation adjustment hole 1011 is provided on the side wall of the housing 1. A plurality of adjustment deformation holes 1013 are also provided along the circumference of the rotation adjustment hole 1011. The plurality of adjustment deformation holes 1013 are specifically provided on the first housing 101. The portion between the mounting hole 1011 and the adjustment deformation hole 1013 constitutes a deformation portion 1014. When the positioning block 1012 engages from the current positioning slot 73 to the next positioning slot 73, it contacts the push adjustment portion 72 on the push adjustment body 7. The push adjustment portion 72 presses the positioning block 1012, causing the positioning block 1012 and the deformation portion 1014 to deform toward the adjustment deformation hole 1013, reducing the size of the adjustment deformation hole 101. Once the positioning block 1012 successfully engages the next positioning slot 73, the adjustment deformation hole 101 returns to its original shape.

[0098] Furthermore, a blocking portion 75 is provided on the push regulating portion 72 to prevent the push regulating body 7 from separating from the housing 1. In the present invention, a blocking portion 75 is provided every other push regulating portion 72, and there are three blocking portions 75 in total. The blocking portions 75 are located close to the inner wall of the housing 1.

[0099] In this Figure 12In the figure, the blocking portion 75 includes a first vertical surface 751 perpendicular to the corresponding push adjustment surface 71, a parallel surface 753 parallel to the corresponding push adjustment surface 71, a transition slope 752 connecting the first vertical surface 751 and the parallel surface 753, and a second vertical surface 754 connecting the parallel surface 753 and perpendicular to the corresponding push adjustment surface 71. During the installation of the push adjustment body 7, the transition slope 752 will contact the mounting hole 1011, squeezing the mounting hole 1011 to cause deformation. When the blocking portion 75 enters the interior of the housing 1, the second vertical surface 754 of the blocking portion 75 close to the first housing 101 will be blocked by the mounting hole 1011, thereby preventing the push adjustment body 7 from separating from the housing 1.

[0100] Further, in Figure 12 In the figure, the first push adjustment portion 721 is stepped, including a first push adjustment portion distal end 7211 and a first push adjustment portion proximal end 7212. The virtual line between the first push adjustment portion distal end 7211 and the central axis Z of the push adjustment body 7 is the seventh virtual line S7, and the virtual line between the first push adjustment portion proximal end 7212 and the central axis Z is the eighth virtual line S8. The length of the seventh virtual line S7 is greater than the length of the eighth virtual line S8. Similarly, the second push adjustment portion 721 to the sixth push adjustment portion 726 respectively include the second push adjustment portion distal end and the second push adjustment portion proximal end, and the sixth push adjustment portion distal end and the sixth push adjustment portion proximal end.

[0101] Preferably, the first to sixth push adjustment surfaces 711 to 716 are respectively provided on the distal ends of the first to sixth push adjustment parts; and the blocking parts 75 are provided at intervals on the distal ends of the first to sixth push adjustment parts.

[0102] Preferably, the distances between the proximal ends of the second and sixth push adjustment parts and the central axis Z of the push adjustment body 7 are the same. The positioning block 1012 is engaged in the positioning slot 73 between the proximal ends of two adjacent push adjustment parts.

[0103] Furthermore, the elastic component 6 is arranged between the front end of the pushing slider 5 and the inner wall of the housing 1, and has an elastic force to push the pushing slider 5 to slide backward.

[0104] Preferably, the elastic component 6 is a reset spring, which is sleeved on the periphery of the negative electrode 203, and one end of the reset spring abuts against the front end of the pushing slider 5, so that the rear end of the pushing slider 5 is in close contact with the pushing adjustment surface 71; the other end of the reset spring abuts against the inner wall of the shell 1, specifically, the other end of the reset spring abuts against the inner wall of the conical portion 1017.

[0105] Furthermore, a push tube 8 is sleeved on the tail of the positive electrode 201, and the push tube 8 is fixedly connected to the push slider 5. A fixing hole 51 for fixing the push tube 8 is provided on the side wall of the push slider 5, and the push tube 8 can be fixed in the fixing hole 51 by embedding, welding, etc.

[0106] Preferably, combined Figure 16 The tail of the insulating sleeve 202 does not wrap the tail of the electrode positive pole 201; the tail of the electrode positive pole 201 is in contact with the push tube 8, and the push tube 8 is made of conductive material and is electrically connected to the RF positive signal cable, thereby transmitting current to the electrode positive pole 201.

[0107] Preferably, Figure 8 In the embodiment, the top and bottom of the pushing slider 5 can slide along the inner wall of the shell 1; and a pushing groove 52 is also provided on the side wall of the pushing slider 5, and a pushing slide 1022 adapted to the pushing groove 52 is correspondingly provided on the inner wall of the second shell 102.

[0108] Preferably, the material of the pushing slider 5 can be ABS, POM, PEEK, PVC, PET, nylon, polymer materials, modified engineering plastics, etc.

[0109] Combine Figure 17 ,exist Figure 17 In the equation, L1=L3-L2, L3=L4+L5, it can be concluded that: L1=L4+L5-L2; wherein L1 is the distance from the front end of the positive electrode 201 to the front end of the negative electrode 203, and L1 is the depth of the positive electrode 201 penetrating the eyeball; L2 is the distance from the front end of the negative electrode 203 to the central axis Z of the push regulating body 7, and the value of L2 is fixed; L3 is the distance from the front end of the positive electrode 201 to the central axis Z of the push regulating body 7, and the value of L3 is adjustable L4 is the distance between the front end of the positive electrode 201 and the rear end of the push slider 5; the value of L4 is fixed. L5 is the distance between the push adjustment surface 71 and the central axis Z of the push adjustment body 7; the value of L5 is adjustable. In the formula L1=L4+L5-L2, since the values ​​of L2 and L4 are fixed, changing the value of L5 will also change L1. This means that by changing the push adjustment surface 71 in contact with the rear end of the push slider 5, the depth of penetration of the positive electrode 201 into the eyeball can be adjusted. Adjusting the penetration depth of the positive electrode 201 into the eyeball in this way is convenient, fast, and highly accurate, and can accurately adjust the penetration depth of the positive electrode 201 within a very small range.

[0110] For example, when the thickness of the sclera + conjunctiva is 1.5 mm (i.e., L1=1.5 mm), the third push adjustment surface 713 with an adjustment value of 1.5 mm is selected; when the thickness of the sclera + conjunctiva is 1.4 mm, the second push adjustment surface 712 with an adjustment value of 1.4 mm is selected; when the thickness of the sclera + conjunctiva is 1.6 mm, the fourth push adjustment surface 714 with an adjustment value of 1.6 mm is selected.

[0111] The present invention also provides a radiofrequency ablation device for reducing intraocular pressure or treating glaucoma, comprising the aforementioned radiofrequency ablation handle, which is electrically connected to an ablation host. The ablation host is electrically connected to the radiofrequency ablation handle via a radiofrequency signal cable, which includes a positive radiofrequency signal cable and a negative radiofrequency signal cable.

[0112] The RF ablation device is used as follows: Sterilize the RF ablation handle using a variety of methods, including gas sterilization (ethylene oxide, formaldehyde, ozone), radiation sterilization (microwave, ultraviolet (UV), X-rays, and gamma rays). Connect the RF ablation handle to the ablation host, which transmits current to the RF ablation electrode 2 on the RF ablation handle via the RF signal cable.

[0113] Before the start of the radiofrequency ablation procedure, an X-ray of the patient's eyes is taken to measure the thickness of the sclera and conjunctiva outside the ciliary body, determine the insertion depth of the electrode positive pole 201, and select the corresponding push adjustment surface 71 based on the insertion depth. The operator can insert the radiofrequency ablation electrode 2 into the patient's eye and drive the ablation host to work. The ablation host outputs current to the electrode positive pole 201, and the current returns to the electrode negative pole 203 through the ciliary body tissue. The ablation effect is mainly concentrated at the first conical tip 2011. In the ciliary body, the ablation band produced by the radiofrequency ablation electrode 2 destroys the aqueous humor tissue of the ciliary body, thereby reducing the production of aqueous humor in the ciliary body, achieving the purpose of lowering intraocular pressure and treating glaucoma. This method has the same effect on open-angle glaucoma and angle-closure glaucoma.

[0114] It can be seen that the present invention discloses a radiofrequency ablation handle for reducing intraocular pressure or treating glaucoma, including a shell and a radiofrequency ablation electrode installed in the shell, the front end of the radiofrequency ablation electrode extends out of the shell; the radiofrequency ablation electrode is cylindrical as a whole, including an electrode positive pole located in the center, an insulating sleeve arranged around the outer periphery of the electrode positive pole, and an electrode negative pole arranged around the outer periphery of the insulating sleeve; the electrode positive pole, the insulating sleeve, and the electrode negative pole are coaxial, and the electrode positive pole and the electrode negative pole can slide relative to each other. After the radiofrequency ablation electrode is energized, an ablation zone is generated between the electrode positive pole and the electrode negative pole, and the ablation zone is used to act on the ciliary body to reduce the production of aqueous humor; the shell is also connected to a pushing mechanism, which is used to adjust the distance between the front end of the electrode positive pole and the front end of the electrode negative pole. In the present invention, the pushing mechanism accurately adjusts the depth of the radiofrequency ablation electrode inserted into the eye to adapt to the eyeballs of different patients and achieve the purpose of precise ablation. The present invention also provides a radiofrequency ablation device for reducing intraocular pressure or treating glaucoma, which is easy to operate and use.

[0115] The above descriptions are merely embodiments of the present invention and are not intended to limit the patent scope of the present invention. Any equivalent structural transformations made using the contents of the present invention's description and drawings, or directly or indirectly applied to other related technical fields, are also included in the patent protection scope of the present invention.

Claims

1. A radiofrequency ablation handle for reducing intraocular pressure or treating glaucoma, characterized by: The invention comprises a shell and a radiofrequency ablation electrode installed in the shell, wherein the front end of the radiofrequency ablation electrode extends out of the shell; the radiofrequency ablation electrode is generally columnar, comprising a positive electrode located in the center, an insulating sleeve arranged around the positive electrode, and a negative electrode arranged around the insulating sleeve; the positive electrode, the insulating sleeve, and the negative electrode are coaxial, the distance between the front end of the positive electrode and the front end of the negative electrode is the depth of the radiofrequency ablation electrode inserted into the eye, and the front end of the negative electrode stays outside the eyeball; when the radiofrequency ablation electrode is energized, an ablation zone is generated between the positive electrode and the negative electrode, and the ablation zone is used to act on the ciliary body to reduce the production of aqueous humor; The housing is further connected to a pushing mechanism, the pushing mechanism is fixedly connected to the positive electrode, the negative electrode is fixedly connected to the housing, the pushing mechanism can drive the positive electrode to move back and forth, adjusting the distance between the front end of the positive electrode and the front end of the negative electrode; The pushing mechanism includes a rotating component, a pushing slider and an elastic component; the rotating component is at least partially exposed outside the shell and is connected to the pushing slider inside the shell through a pushing adjustment body; the pushing adjustment body rotates coaxially with the rotating component, and a plurality of pushing adjustment surfaces are provided along the circumferential ring of the pushing adjustment body, and each virtual line between the pushing adjustment surface and the central axis of the pushing adjustment body corresponds to an adjustment value; the pushing slider is slidably arranged inside the shell, the front end of the pushing slider is fixedly connected to the tail of the positive electrode of the electrode, and the rear end of the pushing slider contacts the pushing adjustment surface; the elastic component is arranged between the front end of the pushing slider and the inner wall of the shell, and has an elastic force that pushes the pushing slider to slide backward.

2. The radiofrequency ablation handle for reducing intraocular pressure or treating glaucoma according to claim 1, characterized in that: The elastic component is a reset spring, which is sleeved on the periphery of the negative electrode, with one end of the reset spring abutting against the front end of the pushing slider and the other end abutting against the inner wall of the shell.

3. The radiofrequency ablation handle for reducing intraocular pressure or treating glaucoma according to claim 1, characterized in that: The push adjustment body is columnar, and a mounting hole for the push adjustment body to pass through is provided on the side wall of the shell; a plurality of protruding push adjustment parts are provided along the circumferential ring of the push adjustment body, each of the push adjustment surfaces corresponds to one push adjustment part, and the push adjustment surface is provided on the outer surface of the push adjustment part.

4. The radiofrequency ablation handle for reducing intraocular pressure or treating glaucoma according to claim 3, characterized in that: The push regulating body is a hollow structure and has a hollow rotating hole. A positioning shaft adapted to the rotating hole is further provided in the shell, and the positioning shaft is inserted into the rotating hole.

5. The radiofrequency ablation handle for reducing intraocular pressure or treating glaucoma according to claim 3, characterized in that: A positioning slot is formed between two adjacent push adjustment parts, and a protruding positioning block that is adapted to the positioning slot is provided on the edge of the mounting hole, so that the positioning block can be engaged in different positioning slots during the rotation of the push adjustment body.

6. The radiofrequency ablation handle for reducing intraocular pressure or treating glaucoma according to claim 5, characterized in that: A rotation adjustment hole is provided on the side wall of the shell, and a plurality of adjustment deformation holes are provided along the circumference of the rotation adjustment hole. The portion between the mounting hole and the adjustment deformation holes constitutes a deformation portion.

7. The radiofrequency ablation handle for reducing intraocular pressure or treating glaucoma according to claim 6, characterized in that: The push regulating portion is further provided with a blocking portion for preventing the push regulating body from separating from the housing.

8. The radiofrequency ablation handle for reducing intraocular pressure or treating glaucoma according to claim 1, characterized in that: The rotating component is an adjusting knob, and the plurality of adjusting values ​​are arranged on a side wall of the adjusting knob along the circumference of the adjusting knob.

9. A radiofrequency ablation device for reducing intraocular pressure or treating glaucoma, characterized by: It comprises the radiofrequency ablation handle according to any one of claims 1 to 8, wherein the radiofrequency ablation handle is electrically connected to an ablation host.

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