An indwelling blood sampling system

Abstract

The present application relates to a kind of indwelling blood sampling systems, the indwelling blood sampling system includes the puncture component for the blood extraction of blood vessel site puncture, the collection component for the temporary storage of extracted blood sample, puncture component and collection component are communicated by connector, the end of connector close to puncture component is connected at the end of puncture component away from blood vessel puncture site, and the end of flow guide tube close to collection component is connected at the end of collection component with opening part.The hollow needle for puncturing into skin and blood vessel in puncture component can be moved along the cannula body of the internal hollow of puncture component, and the central axis in the length direction of hollow needle is arranged in parallel with cannula body.The present application can extract hollow needle and fix cannula body in blood vessel for a long time, facilitate long-term, regular blood extraction work;The design of hemostatic seat can seal pipe to main pipe body when not needing blood extraction, avoid blood outflow, and blood storage cavity can also adjust blood extraction speed and blood extraction amount.

Description

Technical Field

[0001] This invention relates to the field of medical device technology, and in particular to an indwelling blood collection system. Background Technology

[0002] A complete blood count (CBC) is an examination that assesses blood condition and disease by observing changes in the number and morphological distribution of blood cells. With the modernization and automation of laboratory testing, CBCs are now performed by machines. A CBC includes red blood cell count (RBC), hemoglobin (Hb), white blood cell count (WBC), white blood cell differential count, and platelet count (PLT), and is generally divided into three systems: the red blood cell system, the white blood cell system, and the platelet system. Many specific indicators in a CBC are commonly used and sensitive indicators that reflect many pathological changes in the body. Among these, white blood cell count, red blood cell count, hemoglobin, and platelet count are the most valuable for diagnosis. Many patients with unclear causes can benefit from a CBC for auxiliary diagnosis. Furthermore, a CBC is a commonly used indicator for monitoring treatment effectiveness, medication use or discontinuation, treatment continuation or cessation, and disease recurrence or cure. Blood samples for routine blood tests typically require medical staff to draw blood from patients. These tests are often performed for routine checkups, liver function tests, kidney function tests, and infectious diseases. In some diseases requiring long-term treatment, regular blood draws are necessary. Current blood drawing equipment commonly uses straight needles or devices with small lancets, requiring a new needle for each draw. In treatment plans that require long-term, regular blood draws, each puncture causes discomfort for the patient and increases the burden on medical staff.

[0003] A prior art blood collection indwelling needle, as disclosed in patent document CN106334236A, includes a steel needle and a cannula. The steel needle is fixed to the top of the cannula, and a three-way connector is connected to the side wall of the cannula. A switching valve is rotatably connected to the inner wall of the three-way connector. Rotating the switching valve connects the cannula to different channels of the three-way connector. The three-way connector replaces the existing branch pipe structure, forming a blood collection connector and an infusion connector on the side wall of the cannula. When the switching valve connects the blood collection connector to the cannula, the infusion connector closes, and the blood collection connector connects to the blood collection device, allowing blood to be collected through the cannula and blood collection connector. When the switching valve connects the infusion connector to the cannula, the blood collection connector closes, and the infusion connector connects to the infusion device, enabling medication administration.

[0004] The present invention, as disclosed in patent document CN107405119B, discloses a safety blood collection needle structure, including a housing, a needle rod fixing rod located within the housing, and a blood collection needle fixed to the top of the needle rod fixing rod. The top of the housing has a needle outlet, and a positioning block or a connection point with a fracturing edge is provided between the needle rod fixing rod and the housing to fix the needle rod fixing rod. This safety blood collection needle structure fixes the blood collection needle within the housing, preventing unreasonable exposure of the blood collection needle when not in use. When the blood collection needle is in use, external force triggers the tail of the needle rod fixing rod, causing it to slide out from the positioning block, thereby pushing the blood collection needle, or causing the fracturing edge to break, allowing the blood collection needle to pass through the needle outlet for blood collection. This safety blood collection needle has a simple structure and low manufacturing cost. With different configurations, it can achieve single-handed operation and / or be used with a matching blood collection pen, effectively ensuring safe blood collection operations. This invention is applicable to the field of medical devices.

[0005] There are still aspects in the aforementioned prior art that need improvement. For example, the indwelling blood collection needle disclosed in prior art CN106334236A can replace the existing branch tube with a three-way tube and use a switching valve to switch between blood drawing and infusion states. However, it does not consider controlling the blood flow, and for blood drawing, it cannot adjust the blood drawing speed, and blood may leak out during the switching process. Another example is the safety blood collection needle structure disclosed in prior art CN107405119B. Although it ensures the safety of the needle structure when not in use, this structure is not convenient for situations requiring long-term, regular blood drawing. This blood collection needle structure still requires re-puncture each time blood is drawn, increasing workload and patient discomfort.

[0006] Furthermore, on the one hand, there are differences in understanding among those skilled in the art; on the other hand, the inventors studied a large number of documents and patents when making this invention, but due to space limitations, not all details and contents were listed in detail. However, this does not mean that the present invention does not possess the features of these prior art. On the contrary, the present invention already possesses all the features of the prior art, and the applicant reserves the right to add relevant prior art to the background art. Summary of the Invention

[0007] To address the shortcomings of existing technical solutions, this application proposes a blood collection system. The system includes a puncture assembly for extracting blood by piercing a blood vessel and a collection assembly for temporarily storing the extracted blood sample. The puncture assembly and the collection assembly are connected via a connector. One end of the connector near the puncture assembly is connected to the end of the puncture assembly away from the blood vessel puncture site. The other end of the guide tube near the collection assembly is connected to the end of the collection assembly with an opening.

[0008] Preferably, the hollow needle body within the puncture assembly for puncturing into the skin and blood vessels is movable along the hollow cannula body inside the puncture assembly, and the cannula body is arranged parallel to the central axis in the length direction of the hollow needle body.

[0009] The puncture component of the indwelling blood collection device of this application adopts a design in which a hollow needle body is inserted through the inside of the cannula component. During puncture, the cannula body of the cannula component and the hollow needle body are punctured into the blood vessel together. Then the hollow needle body is withdrawn, and the cannula body is fixed inside the blood vessel for a long time through the cannula seat of the cannula component, which facilitates long-term and regular blood collection.

[0010] Preferably, when the connector is not connected, the hollow needle body of the puncture assembly is fitted inside a cannula assembly containing the cannula body, the cannula assembly including the cannula body for inserting into a blood vessel and a main body and cannula seat for holding the puncture assembly.

[0011] Preferably, the hollow needle body extends through the entire puncture assembly. The hollow needle body has a pointed tip at one end near the puncture site, and a cap is connected to the other end of the hollow needle body. The pointed tip and the cap are distributed at both ends of the puncture assembly. The hollow needle body has a needle seat fixedly connected to the cannula seat inside the cannula seat. The hollow needle body can move translatably in the axial direction of the cannula assembly by means of the needle seat. The flexible tube for delivering blood vessels, which is connected to the cannula body, is sleeved on the hollow needle body.

[0012] Preferably, the sleeve assembly is further provided with a hemostatic seat that penetrates the interior of the main tube. The hemostatic seat is fixedly connected to the top end of the main tube, thereby preventing blood inside the main tube from seeping out from the through hole of the hemostatic seat that communicates with the main tube under the action of gravity. The hemostatic seat is provided with a hemostatic plug that matches the through hole. The hemostatic plug can enter the interior of the main tube through the through hole to block the blood flow through the hose, thereby achieving the effect of hemostasis.

[0013] Preferably, the end of the hemostatic plug of the hemostatic seat that does not enter the main body is connected to a limiting cap with a diameter larger than that of the through hole. The limiting cap is fixedly connected to the hemostatic plug to facilitate the control of the position of the hemostatic plug in the through hole and the main body. The hemostatic plug is provided with a retaining post that extends a certain distance from the side wall of the hemostatic plug.

[0014] Preferably, the sidewall of the through hole is provided with a first groove and a second groove for positioning the hemostatic plug. The direction of the first groove is consistent with the axial direction of the through hole, and the direction of the second groove is consistent with the radial direction of the through hole. The first groove and the second groove are connected to form an exchange area. The locking post of the hemostatic plug can slide in the first groove and the second groove. The locking post slides in the first groove due to the axial movement of the hemostatic plug in the through hole. The locking post slides in the second groove due to the rotation of the hemostatic plug in the through hole about the central axis of the through hole. The ends of the first groove and the second groove away from the exchange area are respectively provided with a first locking position and a second locking position to hold the locking post.

[0015] The cannula assembly of this application is provided with the hemostatic seat, which controls the patency of the main tube of the cannula assembly, thereby controlling whether blood flows through the main tube. When blood is needed, the hemostatic plug of the hemostatic seat is removed from the main tube to allow blood flow; when blood is not needed, the hemostatic plug of the hemostatic seat is inserted into the main tube to block the tube and prevent blood from flowing out, thus achieving hemostasis.

[0016] Preferably, the main body has a plurality of cavities disposed outside the flexible tubes along the axis of the main body, and each cavity has at least a flexible tube communicating with the axis of the main body.

[0017] According to another configuration, the main body has at least two cavities, which are disposed outside the hose on the axis of the main body, and each cavity has at least one branch connecting to the hose on the axis of the main body, and further, the branch forms at least one opening on the side wall of the hose.

[0018] Preferably, the main body is equipped with the aforementioned self-locking valve, without a hemostatic seat or plug. Furthermore, the self-locking valve has a piston-like structure, capable of blocking the hose and moving within it to a certain extent. The self-locking valve has a spring-loaded structure along the hose's axial direction, allowing it to move a certain distance along the hose before being held in a specific position within the hose by a spring structure without additional external force.

[0019] Preferably, the specific position is set such that the bottom of the self-locking valve in the thickness direction is at least in a position that allows a portion of the blood to enter a cavity through only one opening of the tubing via a branch, but not through another opening into another cavity.

[0020] This specific positioning ensures that the bottom of the self-locking valve is below the opening; at least, the bottom of the self-locking valve is flush with the bottom of the opening. This minimizes the deposition of blood other than that entering the cavity in the indwelling structure. The bottom of the self-locking valve has a side-opening groove. When this groove aligns with one of the openings, it connects the vascular channel to the branch, allowing blood to flow through the groove into the branch and then into the cavity. To ensure that blood in the tubing can only enter one cavity through one opening at a time, the self-locking valve is further configured to switch the alignment of the side-opening groove with one of the openings during each blood draw connection, moving the previously aligned opening to the next. Blood draw connection refers to the operation of external force aligning the connector with the main tube when blood is needed.

[0021] Based on the above configuration, cavities can be arranged radially around the axial direction of the main tube. The aforementioned press-and-rotate structure ensures that each blood draw allows the deposited blood to enter the corresponding, non-communicating cavity. Furthermore, each cavity can be numbered according to the rotation sequence of the self-locking valve, indicating which blood draw it contained during which session. Each cavity has a membrane-sealed opening on the outside of the main tube, similar to the disposable, puncture-resistant rubber opening of a vaccine vial. When needed, the deposited blood can be extracted using a disposable syringe, ensuring that each drawn blood sample is free of impurities. This prevents contamination parameters from entering the drawn blood, resulting in more accurate test data and better assessment of the patient's condition.

[0022] Preferably, the collection assembly has a blood storage chamber for storing blood and a protective chamber for protecting the blood storage chamber. The protective chamber encloses the blood storage chamber inside. The bottom of the protective chamber is provided with a pressure regulating part for controlling the gas pressure inside the blood storage chamber, and the top of the protective chamber is provided with a blood connection port for communicating with the unidirectional fluid inside the blood storage chamber.

[0023] Preferably, the protective cavity is provided with a first baffle that divides the protective cavity into a bearing area for the blood storage cavity and a control area for regulating the pressure in the blood storage cavity. A pressure regulating unit for regulating the pressure in the blood storage cavity is provided in the control area. The pressure regulating unit, in conjunction with the first baffle and a second baffle located between the first baffle and the bottom of the protective cavity, is equipped with a driving assembly. The driving assembly includes a first transmission wheel located inside the first baffle, which can restrict its vertical movement via the upper and lower surfaces of the first baffle. The inner surface of the first transmission wheel has threads. A second transmission wheel, also located inside the first baffle, is located on the side of the first transmission wheel and can drive the first transmission wheel to rotate. The second transmission wheel is fixedly connected to a vertically placed transmission rod. The other end of the transmission rod is fixedly connected to a third transmission wheel. The transmission rod is fitted onto a transmission support column that can support the rotation of the transmission rod. The transmission support column is fixedly welded to the bottom of the protective cavity. A control wheel on the protective cavity shell can drive the third transmission wheel to rotate, thereby driving the first transmission wheel to rotate via the transmission rod and the second transmission wheel.

[0024] Preferably, the drive assembly further includes a piston capable of axial movement inside the blood storage chamber. The piston is connected to a threaded rod that passes through the first drive wheel and matches the thread of the first drive wheel. The rotation of the first drive wheel enables the piston connected to the threaded rod to move inside the blood storage chamber. A limit block is connected to one end of the threaded rod away from the piston. The threaded rod is fitted onto a lifting support column that is fixedly connected to the bottom of the protective cavity.

[0025] A second baffle is provided between the first baffle and the bottom of the protective cavity. The second baffle is provided with a first ball pulley fitted outside the threaded rod and a second ball pulley fitted on the transmission rod, which further defines the position of the threaded rod and the transmission rod.

[0026] The collection component of this application can also adjust the pressure in the blood storage chamber connected to the puncture component via a connector, thereby controlling the speed and volume of blood collection.

[0027] This application also provides a method for using an indwelling blood collection system, wherein a puncture component for puncturing a blood vessel to extract blood is inserted into a suitable blood vessel site, and after the hollow needle inside the puncture component is extracted, a connector is used to connect the tail end of the puncture component to a collection component for temporarily storing the extracted blood sample.

[0028] Preferably, the hollow needle body of the puncture assembly is connected to a cap at the end away from the puncture site. The hollow needle body is pulled out from the main body and cannula seat of the puncture assembly through the cap, leaving only the cannula body that entered the blood vessel along with the hollow needle body in the blood vessel. The cannula seat of the puncture assembly is then fixed with medical tape to prevent the cannula body from falling off or shifting from the blood vessel.

[0029] Preferably, the hemostatic plug on the puncture assembly can be adjusted by a limiting cap on the hemostatic plug to move within the through hole of the hemostatic seat and block the main tube. When blood is needed, the limiting cap places the locking pin on the hemostatic plug at the first locking position of the first locking groove, at which time the main tube is unobstructed. When blood is not needed, the limiting cap moves the locking pin on the hemostatic plug from the first locking position along the first locking groove to the exchange area formed by the first locking groove and the second locking groove connecting the first locking groove. Then, the limiting cap is rotated to move the locking pin to the second locking position of the second locking groove, at which time the main tube is blocked.

[0030] Preferably, when the puncture assembly and the collection assembly are connected through the connector, the pressure inside the blood storage chamber in the protective chamber is adjusted by adjusting the control wheel on the protective chamber of the collection assembly, thereby controlling the blood collection volume and blood collection speed. Attached Figure Description

[0031] Figure 1 This is a simplified overall structural diagram of the indwelling blood collection system of the present invention;

[0032] Figure 2 This is a simplified structural diagram of the puncture component of the indwelling blood collection system of the present invention;

[0033] Figure 3 This is a simplified structural diagram of the collection component of the indwelling blood collection system of the present invention;

[0034] Figure 4 This is a cross-sectional structural diagram of the puncture component of the indwelling blood collection system of the present invention;

[0035] Figure 5 This is a cross-sectional structural diagram of the collection component of the indwelling blood collection system of the present invention;

[0036] Figure 6 This is a cross-sectional structural diagram of the hemostatic seat of the indwelling blood collection system of the present invention;

[0037] Figure 7 This is a simplified structural diagram of another embodiment of the puncture component of the indwelling blood collection system of the present invention.

[0038] List of reference numerals

[0039] 100: Puncture assembly; 200: Collection assembly; 120: Connector; 101: Hollow needle body; 102: Cannula body; 103: Cannula seat; 104: Main tube body; 105: Hemostatic seat; 106: Hemostatic plug; 107: Limiting cap; 108: First slot; 109: Second slot; 110: Locking post; 111: First locking position; 112: Second locking position; 113: Plug; 114: Holding wing; 115: Connecting cavity; 116: Needle seat; 117: Connecting post; 118: Cap; 119: Through Hole; 121: Tube; 122: Puncture needle; 123: Holder; 201: Blood storage chamber; 202: Protective chamber; 203: First baffle; 204: Piston; 205: Threaded rod; 206: First drive wheel; 207: Second drive wheel; 208: Third drive wheel; 209: Drive rod; 210: Second baffle; 211: Lifting support column; 212: Drive support column; 213: First ball pulley; 214: Second ball pulley; 215: Limiting block; 216: Control wheel; 217: Connection port. Detailed Implementation

[0040] The present invention will now be described in detail with reference to the accompanying drawings.

[0041] Example 1

[0042] like Figure 1 The illustrated blood collection system includes a puncture assembly 100 for drawing blood from a blood vessel and a collection assembly 200 for temporarily storing the drawn blood sample. The puncture assembly 100 and the collection assembly 200 are connected by a connector 120. One end of the connector 120 near the puncture assembly 100 is connected to the end of the puncture assembly 100 away from the blood vessel puncture site, and one end of the guide tube near the collection assembly 200 is connected to the end of the collection assembly 200 with an opening.

[0043] Preferably, the hollow needle 101 inside the puncture assembly 100 for puncturing into the skin and blood vessels is movable along the hollow cannula 102 inside the puncture assembly 100, and the cannula 102 is arranged parallel to the central axis in the length direction of the hollow needle 101.

[0044] The puncture component 100 of the indwelling blood collection device of this application adopts a design in which a hollow needle body 101 penetrates inside the cannula component. During puncture, the cannula body 102 of the cannula component and the hollow needle body 101 are punctured into the blood vessel together. Then the hollow needle body 101 is withdrawn, and the cannula body 102 is fixed inside the blood vessel for a long time through the cannula seat 103 of the cannula component, which facilitates long-term and regular blood collection.

[0045] Preferably, when the connector 120 is not connected, the hollow needle body 101 of the puncture assembly 100 is assembled inside a cannula assembly including a cannula body 102 for inserting into a blood vessel and a main body 104 and a cannula seat 103 for holding the puncture assembly 100.

[0046] according to Figure 2 As shown, the hollow needle body 101 runs through the entire puncture assembly 100. The hollow needle body 101 has a tip at one end near the puncture site, and a cap 118 is connected to the other end of the hollow needle body 101. The tip and the cap 118 are distributed at both ends of the puncture assembly 100. The hollow needle body 101 has a needle seat 116 fixedly connected to the cannula seat 103 inside the cannula seat 103. The hollow needle body 101 can move in the axial direction of the cannula assembly by means of the needle seat 116. The flexible tube 121 for delivering blood vessels, which is connected to the cannula body 102, is sleeved on the hollow needle body 101.

[0047] according to Figure 4 As shown, the cannula seat 103 is provided with holding wings 114 at both ends, which makes it easier for medical staff to hold it. After the puncture is completed and the hollow needle body 101 is removed, the holding wings 114 also make it easier to fix the puncture component 100 at the puncture site.

[0048] Preferably, the tail end of the sleeve seat 103 is provided with a connecting cavity 115, and a needle seat 116 is provided in the connecting cavity 115. The needle seat 116 is designed as a multi-spoke structure connected to the side wall of the connecting cavity 115. There is a fine hole in the center of the multi-spoke structure that allows the hollow needle 101 to pass through, so that the hollow needle 101 can be pulled out.

[0049] Preferably, the tail end of the hollow needle body 101 is connected to a connecting post 117 that can be detachably connected to the connecting cavity 115. The hollow needle body 101 is fixedly connected to the connecting post 117, and the cap 118 is fixedly connected to the end of the connecting post 117 away from the hollow needle body 101. When the needle body is withdrawn, the connecting post 117 is detached from the connecting cavity 115 and smoothly withdrawn from the needle body seat 116.

[0050] Preferably, the connection between connector 120 and puncture assembly 100 is detachable. One end of connector 120 is connected to a retainer 123 within connection cavity 115 that communicates with tubing 121. The connection method can be threaded, insert, or nested. Specifically, a removable heparin cap can be provided within retainer 123 for further sealing of tubing 121.

[0051] Preferably, the puncture needle 122 of the syringe can also be inserted into the seat 123 of the connecting cavity 115. A certain amount of saline is injected into the seat 123 and the inside of the tubing 121 through the syringe. After the injection is completed, the seat 123 is sealed with a heparin cap to further seal and protect the inside of the tubing 121, preventing the blood inside the puncture structure 100 left in the blood vessel from clotting when blood is not drawn.

[0052] Example 2

[0053] Example 2 is a further improvement on Example 1, and the repeated content will not be described again.

[0054] Reference Figure 1 and Figure 2 The cannula assembly is also provided with a hemostatic seat 105 that penetrates the interior of the main tube 104. The hemostatic seat 105 is fixedly connected to the top of the main tube 104, thereby preventing blood in the main tube 104 from seeping out from the through hole 119 of the hemostatic seat 105 that communicates with the main tube 104 under the action of gravity. The hemostatic seat 105 is provided with a hemostatic plug 106 that matches the through hole 119. The hemostatic plug 106 can enter the interior of the main tube 104 through the through hole 119 to block the blood flow through the hose 121, thereby achieving the hemostasis effect.

[0055] The cannula assembly of this application is further provided with a hemostatic seat 105, which controls the patency of the main body 104 of the cannula assembly, thereby controlling whether blood flows within the main body 104. When blood draw is required, the hemostatic plug 106 of the hemostatic seat 105 is removed from the main body 104 to allow blood flow. When blood draw is not required, the hemostatic plug 106 of the hemostatic seat 105 is inserted into the main body 104 to block the main body 104, preventing blood from flowing out and achieving hemostasis.

[0056] according to Figure 6 As shown, the end of the hemostatic plug 106 of the hemostatic seat 105 that does not enter the main body 104 is connected to a limiting cap 107 with a diameter larger than that of the through hole 119. The limiting cap 107 is fixedly connected to the hemostatic plug 106, so as to facilitate the control of the position of the hemostatic plug 106 in the through hole 119 and the main body 104. The hemostatic plug 106 is provided with a retaining post 110 that extends a distance from the side wall of the hemostatic plug 106.

[0057] Preferably, the sidewall of the through hole 119 is provided with a first groove 108 and a second groove 109 for positioning the hemostatic plug 106. The direction of the first groove 108 is consistent with the axial direction of the through hole 119, and the direction of the second groove 109 is consistent with the radial direction of the through hole 119. The first groove 108 and the second groove 109 are connected to form an exchange area. The locking post 110 of the hemostatic plug 106 can slide in the first groove 108 and the second groove 109. The locking post 110 slides in the first groove 108 due to the axial movement of the hemostatic plug 106 in the through hole 119. The locking post 110 slides in the second groove 109 due to the rotation of the hemostatic plug 106 in the through hole 119 about the central axis of the through hole 119. The ends of the first groove 108 and the second groove 109 away from the exchange area are respectively provided with a first locking position 111 and a second locking position 112 to hold the locking post 110.

[0058] Preferably, the first slot 108 and the second slot 109 are perpendicular to each other, and the first slot 111 and the second slot 112 are provided with protrusions on both sides. By applying a slight external force, the locking pin 110 of the hemostatic plug 106 can be moved to the inside or outside of the slot, thereby adjusting the locking pin 110 of the hemostatic plug 106.

[0059] Preferably, the end of the hemostatic plug 106 near the main tube 104 is connected to a plug head 113 capable of blocking the main tube 104. The plug head 113 is designed as a disc-shaped structure with the same inner diameter as the main tube 104. The plane of the disc-shaped structure is perpendicular to the axial direction of the main tube 104, so that when the plug head 113 enters the main tube 104, it can fully block the main tube 104.

[0060] Preferably, the plug 113 is made of the same material as the heparin cap (PC / isoprene). The heparin cap has a good sealing effect on the indwelling tube. The plug 113 of the present invention is made of this material and also needs to be able to seal the main tube 104 when blocking the main tube 104.

[0061] Preferably, the end of the connector 120 furthest from the puncture component 100 can be configured as a puncture needle 122, which is directly connected to the interior of the connector 120. When blood collection is not required, the needle tip of the puncture needle 122 is capped to prevent environmental contaminants from entering the puncture needle 122 or the connector 120. When blood collection is needed, the cap of the puncture needle 122 is removed, and the puncture needle 122 is inserted into the collection component 200. Under this configuration, the blood connection port 217 of the collection component 200 is configured as a piston that can be punctured by the puncture needle 122. The shape of the collection component 200 can be any shape capable of collecting blood; commonly, it can be a closed test tube. This configuration allows for the pre-preparation of collection components 200 capable of holding the target blood volume. After one collection component 200 is full, the puncture needle 122 is removed and inserted into another pre-prepared collection component 200, enabling quantitative blood collection while avoiding the inconvenience of changing other collection components 200.

[0062] Example 3

[0063] Example 3 is a further improvement based on Example 1 and Example 2, and the repeated content will not be repeated.

[0064] according to Figure 3 and 5 As shown, the collection component 200 has a blood storage chamber 201 for storing blood and a protective chamber 202 for protecting the blood storage chamber 201. The protective chamber 202 encloses the blood storage chamber 201 inside. The bottom of the protective chamber 202 is provided with a pressure regulating part for controlling the gas pressure inside the blood storage chamber 201. The top of the protective chamber 202 is provided with a blood connection port 217 for communicating with the unidirectional fluid inside the blood storage chamber 201.

[0065] Preferably, the protective cavity 202 is provided with a first baffle 203 that divides the protective cavity 202 into a bearing area for a blood storage cavity 201 and a control area for regulating the pressure in the blood storage cavity 201. A pressure regulating unit for regulating the pressure in the blood storage cavity 201 is provided in the control area. The pressure regulating unit is combined with the first baffle 203 and a second baffle 210 provided between the first baffle 203 and the bottom of the protective cavity 202 and is provided with a driving component. The drive assembly includes a first transmission wheel 206 disposed inside the first baffle 203, which restricts the vertical movement of the first transmission wheel 206 by means of the upper and lower surfaces of the first baffle 203. The inner surface of the first transmission wheel 206 has threads. A second transmission wheel 207 disposed inside the first baffle 203 is disposed on the side of the first transmission wheel 206, which can drive the first transmission wheel 206 to rotate. The second transmission wheel 207 is fixedly connected to a vertically placed transmission rod 209. The other end of the transmission rod 209 is fixedly connected to a third transmission wheel 208. The transmission rod 209 is fitted onto a transmission support column 212 that can support the rotation of the transmission rod 209. The transmission support column 212 is fixedly welded to the bottom of the protective cavity 202. A control wheel 216 disposed on the housing of the protective cavity 202 can drive the third transmission wheel 208 to rotate, thereby driving the first transmission wheel 206 to rotate through the transmission rod 209 and the second transmission wheel 207.

[0066] Preferably, the drive assembly further includes a piston 204 capable of axial movement within the blood storage chamber 201. The piston 204 is connected to a threaded rod 205 that passes through the first transmission wheel 206 and matches the thread of the first transmission wheel 206. The rotation of the first transmission wheel 206 enables the piston 204 connected to the threaded rod 205 to move within the blood storage chamber 201. A limit block 215 is connected to the end of the threaded rod 205 away from the piston 204. The threaded rod 205 is fitted onto a lifting support column 211 that is fixedly connected to the bottom of the protective chamber 202.

[0067] A second baffle 210 is provided between the bottom of the first baffle 203 and the protective cavity 202. The second baffle 210 is provided with a first ball pulley 213 fitted outside the threaded rod 205 and a second ball pulley 214 fitted on the transmission rod 209, which further defines the position of the threaded rod 205 and the transmission rod 209.

[0068] The collection component 200 of this application can also adjust the pressure in the blood storage chamber 201, which is connected to the puncture component 100 via the connector 120, thereby controlling the speed and volume of blood collection.

[0069] This application also provides a method for using an indwelling blood collection system, wherein a puncture component 100 for drawing blood from a blood vessel is inserted into a suitable blood vessel, and after the hollow needle body 101 inside the puncture component 100 is removed, a connector 120 is used to connect the tail end of the puncture component 100 to a collection component 200 for temporarily storing the drawn blood sample.

[0070] Preferably, the hollow needle body 101 of the puncture assembly 100 is connected to a cap 118 at the end away from the puncture site. The hollow needle body 101 is pulled out from the main body 104 and the cannula seat 103 of the puncture assembly 100 through the cap 118, leaving only the cannula body 102, which enters the blood vessel together with the hollow needle body 101, in the blood vessel. The cannula seat 103 of the puncture assembly 100 is then fixed with medical tape to prevent the cannula body 102 from falling off or shifting from the blood vessel.

[0071] Preferably, the hemostatic plug 106 on the puncture assembly 100 can be adjusted by the limiting cap 107 on the hemostatic plug 106 to move within the through hole 119 of the hemostatic seat 105 and block the main body 104. When blood is needed, the retaining post 110 on the hemostatic plug 106 is placed at the first retaining position 111 of the first retaining groove 108 through the limiting cap 107, at which time the main body 104 is unobstructed. When blood is not needed, the retaining post 110 on the hemostatic plug 106 is moved from the first retaining position 111 along the first retaining groove 108 through the limiting cap 107 to the exchange area formed by the first retaining groove 108 and the second retaining groove 109 connecting the first retaining groove 108. Then, the limiting cap 107 is rotated to move the retaining post 110 to the second retaining position 112 of the second retaining groove 109, at which time the main body 104 is blocked.

[0072] Preferably, when the puncture assembly 100 and the collection assembly 200 are connected by the connector 120, the pressure inside the blood storage chamber 201 in the protective chamber 202 is adjusted by adjusting the control wheel 216 on the protective chamber 202 of the collection assembly 200, thereby controlling the blood collection volume and blood collection speed.

[0073] Preferably, a bleeding port penetrating the blood storage chamber 201 and the protective chamber 202 is also provided at the top of the blood storage chamber 201 of the collecting component 200. This bleeding port is only opened when the collected blood is drawn out of the blood storage chamber 201, and is closed at other times. More specifically, the opening and closing state of the bleeding port can be manually adjusted by setting a piston or the like, or it can be configured to open automatically under high pressure. When it is necessary to remove blood from the blood storage chamber 201, the sliding control wheel 216 adjusts the volume of the blood storage chamber 201 to change the internal pressure and further control the outflow of blood. Alternatively, the bleeding port can be closed by fixing a piston. When it is necessary to draw blood, a syringe is used to puncture the needle 122 of the syringe through the bleeding port into the blood storage chamber 201 to draw out the blood.

[0074] Example 4

[0075] Example 4 is a further improvement based on the foregoing examples, and the repeated content will not be described again.

[0076] This embodiment addresses situations requiring multiple or prolonged blood draws in certain medical procedures. It incorporates the concept of indwelling needles used in another puncture mode—indwelling infusion puncture—into its blood draw puncture mode. However, blood draws and infusions are different medical procedures. The most significant difference is that infusion involves introducing external medications or other substances into the patient's body, while blood draws involve removing blood from the patient's body. The flow of substances in these two procedures is different, even opposite. Due to the pressure (blood pressure) within the blood vessels, a portion of the blood at the puncture site is pumped into the puncture assembly 100. To prevent unintended blood leakage from the puncture assembly 100, this solution incorporates a controllable blocking structure, such as the hemostatic seat 105 and hemostatic plug 106 described above. Additionally, a self-locking valve structure, such as a valve-like structure or a duckbill valve, can be configured. The connector 120 connection portion can be configured with a trigger structure. This trigger structure opens the self-locking valve when the connector 120 is connected to the main tube 104, allowing blood to flow within the tube under controlled conditions, i.e., when blood is to be drawn. The trigger structure can be, for example, a rod or a thin rod. During connection, the rod makes perpendicular contact with the self-locking valve, and the thrust causes the valve to open, thereby opening the blood passage for blood drawing.

[0077] The purpose of blood draws is generally to test various parameters in the blood and analyze certain aspects of the patient's condition, such as their illness and physiological state. The changes in these parameters are crucial and require precision. For example, the postprandial glycemic index of diabetic patients needs precise measurement to predict their insulin intervention. However, unlike disposable blood-drawing needles, while indwelling catheters avoid the pain and discomfort of repeated punctures, their inherent design inevitably results in some backflow of blood, also known as deposited blood. This deposited blood is pumped into the cavity of the indwelling catheter by the body's blood pressure pump and remains there between blood draws. To prevent clotting of this relatively "non-circulating" blood, current technology coats or applies anticoagulants, such as heparin or EDTA, to the cavity wall and even the aforementioned self-locking valve or hemostatic plug 106 to prevent coagulation and blockage of the indwelling needle. However, what current technology fails to recognize is that, firstly, anticoagulants gradually diminish and become ineffective during the binding process with blood, especially in blood-drawing settings. Unlike infusion settings, there is no continuous infusion of medication to prevent backflow. Instead, when blood is not being drawn, backflowing blood accumulates in the indwelling catheter for an extended period. Compared to infusion time, the proportion of blood-drawing time in the total indwelling time is negligible. Therefore, in blood-drawing settings, the probability of anticoagulant inactivation increases significantly, making blood coagulation in the indwelling catheter more likely. Secondly, given the above discussion on the role of blood drawing, the quality of the drawn blood... The amount of blood drawn is one of the important parameters to consider. Furthermore, the freshness of the blood is an important parameter to ensure the accuracy of subsequent laboratory analysis. Since the deposited blood is the blood left in the indwelling structure after the previous blood draw, the levels of various substances in the blood can only be close to the levels of various substances in the blood drawn at the previous time. In fact, some substances may even change due to long-term deposition. However, the deposited blood cannot represent the levels of various substances in the next blood collection, and it will enter the next blood collection along with the previous blood draw, thus causing "parameter contamination" to a certain extent in the next blood test analysis.

[0078] For example, taking a blood test for a diabetic patient as an example, the patient has blood drawn half an hour after a meal, and the blood test shows a blood glucose level of A. Half an hour later, the same blood is drawn again through an indwelling device, and the blood glucose level is B. If the patient had blood drawn directly through a puncture at this time, the blood glucose level would be C. Ideally, based on the normal physiological activity of insulin in lowering blood glucose, A > B = C. However, in reality, A > B > C. The reason for the mismatch between the actual and ideal state is that the deposited blood is mixed into the blood drawn half an hour later. As a result, the relatively high blood glucose level in the deposited blood is mixed into the blood drawn half an hour later, causing the test value B to be greater than C. This is detrimental to the accurate medical diagnosis of the patient's insulin intervention ability. The doctor may conclude that the patient's insulin intervention level is low based on the test result B, which may be significantly different from the actual situation.

[0079] Based on the aforementioned problems, in this embodiment, the main body 104 has at least two cavities. The cavities are disposed outside the hose 121 along the axis of the main body 104, and each cavity has at least one branch connecting to the hose 121 along the axis of the main body 104. Furthermore, the branch forms at least one opening on the side wall of the hose 121.

[0080] Preferably, the self-locking valve described above is disposed within the main body 104, without the hemostatic seat 105 and hemostatic plug 106. Further, the self-locking valve has an overall piston-like structure, capable of blocking the hose 121 and moving to a certain extent within the hose 121. The self-locking valve is provided with a spring-loaded structure along the axial direction of the hose 121, allowing it to move a certain distance along the hose 121 before being held in a specific position within the hose 121 by a spring structure without additional external force.

[0081] Preferably, the specific position is set such that the bottom of the self-locking valve in the thickness direction is at least in a position that allows a portion of the blood to enter a cavity through only one of the openings in the tubing 121 via a branch, but not through the other openings into another cavity.

[0082] Preferably, this specific position places the bottom of the self-locking valve below the opening; at least, the bottom of the self-locking valve is flush with the bottom of the opening. This minimizes the deposition of blood other than that entering the cavity in the indwelling structure. The bottom of the self-locking valve has a side-opening groove. When the side-opening groove aligns with one of the openings, it connects the vascular channel and the branch, allowing blood to enter the branch and then the cavity through the side-opening groove. To ensure that blood in the tubing 121 can only enter one cavity through one opening at a time, the self-locking valve is further configured to switch the alignment state of the side-opening groove with one of the openings during each blood draw connection, switching the previously aligned opening to the next. Blood draw connection refers to the operation of external force connecting the connector 120 to the main body 104 when blood is needed.

[0083] For example, the docking of connector 120 with main body 104 is an insertion operation. The interface of connector 120 exerts downward pressure on the self-locking valve along the axial direction of main body 104, causing the self-locking valve to move downward. When it moves to a predetermined position, connector 120 further applies force to open the valve's valve-like structure, connecting the tubing 121 to connector 120, thereby allowing blood to be drawn. The self-locking valve can also be further configured as a press-and-rotate structure similar to a ballpoint pen, so that when blood drawing is complete and connector 120 is pulled out, the self-locking valve can rotate during springback, allowing its side opening groove to be rotated to connect with another opening. The thickness of the self-locking valve is configured such that when it is docked during blood drawing and moved to the predetermined position, it can still block the opening based on the portion of its sidewall without the side opening groove.

[0084] Based on the above configuration, cavities can be arranged radially around the axial direction of the main tube 104. Through the aforementioned press-and-rotate structure, each blood draw allows the deposited blood to enter the corresponding, non-communicating cavity. Furthermore, each cavity can be numbered according to the rotation sequence of the self-locking valve, indicating which blood draw it represents. Each cavity has a membrane-sealed opening on the outer side of the main tube 104, similar to the disposable, puncture-resistant opening made of rubber in a vaccine vial, allowing the deposited blood to be extracted using a disposable syringe when needed. In effect, this solution implements a blood draw buffer backup, accurately storing backup blood with the same or similar levels of substance content as each drawn blood sample. In cases where the drawn blood is damaged, contaminated, or produces unexpected data during testing, these backup blood samples can be used for data calibration, secondary testing, remedial testing, and other remedial measures. Furthermore, each cavity can be individually configured with an anticoagulant, which prevents the anticoagulant from becoming ineffective due to prolonged use of the product and thus avoids blood clotting. It also prevents deposited blood from entering the sample tube during blood collection, thereby making the test data more accurate and avoiding "parameter contamination".

[0085] It should be noted that the specific embodiments described above are exemplary, and those skilled in the art can devise various solutions inspired by the disclosure of this invention. These solutions all fall within the scope of this invention and its protection. Those skilled in the art should understand that this specification and its accompanying drawings are illustrative and not intended to limit the scope of the claims. The scope of protection of this invention is defined by the claims and their equivalents.

Claims

1. A system for blood sampling, comprising: a puncture assembly for extracting blood from a blood vessel site; a collection assembly for temporarily storing the extracted blood sample; characterized in that, the puncture assembly and the collection assembly are connected through a connector, and the collection assembly adjusts the pressure in a blood storage cavity connected with the puncture assembly through the connector to control the speed and amount of blood extraction, the puncture assembly comprises a hollow needle body and a cannula body, the hollow needle body brings the cannula body into the blood vessel when puncturing the skin and blood vessel, the hollow needle body is withdrawn along the central axis of the puncture assembly, after withdrawal, the cannula body is connected with a hose inside the puncture assembly and used for conveying the extracted blood, the hose is provided with a plurality of openings on the side wall, each opening is connected to a plurality of cavities arranged inside the main pipe body through a branch, an anticoagulant is arranged in each cavity, the hose is connected to the branch containing the anticoagulant in a rotating manner, and a self-locking valve is further arranged on the hose, the self-locking valve ensures that the blood in the hose only enters one of the cavities through one of the openings, the collection assembly has a blood storage cavity for storing blood and a protection cavity for protecting the blood storage cavity, the protection cavity wraps the blood storage cavity inside, the bottom of the protection cavity is provided with a gas pressure adjusting part for controlling the gas pressure in the blood storage cavity, and the top end of the protection cavity is provided with a connecting port for connecting the blood flowing in one-way manner in the blood storage cavity, a first baffle is arranged in the protection cavity for dividing the protection cavity into a bearing area of the blood storage cavity and a control area for adjusting the pressure in the blood storage cavity, a gas pressure adjusting part for adjusting the pressure in the blood storage cavity is arranged in the control area, the gas pressure adjusting part comprises a driving assembly arranged in combination with the first baffle and a second baffle arranged between the first baffle and the bottom of the protection cavity, the driving assembly comprises a first transmission wheel arranged inside the first baffle and limiting the vertical movement of the first baffle through the upper and lower surfaces of the first baffle, the inner surface of the first transmission wheel is provided with threads, the side surface of the first transmission wheel is provided with a second transmission wheel arranged inside the first baffle and driving the first transmission wheel to rotate, the second transmission wheel is fixedly connected with a vertically arranged transmission rod, the other end of the transmission rod is fixedly connected with a third transmission wheel, the transmission rod is sleeved on a transmission support column supporting the rotation of the transmission rod, the transmission support column is fixedly welded on the bottom of the protection cavity, and a control wheel arranged on the shell of the protection cavity drives the third transmission wheel to rotate, so as to drive the first transmission wheel to rotate through the transmission rod and the second transmission wheel.

2. The indwelling blood sampling system of claim 1, wherein The hollow needle body (101) of the puncture assembly (100) is arranged inside a cannula assembly comprising the cannula body (102) and a main pipe body (104) and a cannula seat (103) for holding the puncture assembly (100).

3. The indwelling blood sampling system of claim 2, wherein The hollow needle body (101) penetrates through the entire puncture assembly (100), and the hollow needle body (101) is provided with a needle body seat (116) fixedly connected with the cannula seat (103) in the inside of the cannula seat (103).

4. The indwelling blood sampling system of claim 2, wherein The sleeve assembly is further provided with a hemostatic seat (105) penetrating the inside of the main pipe body (104), the hemostatic seat (105) is provided with a hemostatic plug (106) matching the through hole (119), the hemostatic plug (106) can enter the inside of the main pipe body (104) from the through hole (119) to block the blood flow through the hose (121).

5. The indwelling blood sampling system of claim 4, wherein The end of the hemostatic seat (105) where the hemostatic plug (106) does not enter the main pipe body (104) is connected with a limiting cover (107) with a diameter larger than the hole diameter of the through hole (119), the limiting cover (107) is fixedly connected with the hemostatic plug (106), thereby facilitating the control of the position of the hemostatic plug (106) in the through hole (119) and the main pipe body (104), the hemostatic plug (106) is provided with a clamping column (110) extending from the side wall part of the hemostatic plug (106) by a distance.

6. The indwelling blood sampling system of claim 5, wherein, The side wall of the through hole (119) is provided with a first clamping groove (108) and a second clamping groove (109) for limiting the position of the hemostatic plug (106), the clamping column (110) can be respectively retained in a first clamping position (111) of the first clamping groove (108) and a second clamping position (112) of the second clamping groove (109), the clamping column (110) changes the hemostatic state of the hemostatic seat (105) by changing between different clamping positions.

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