A radiofrequency ablation handle and radiofrequency ablation device for reducing intraocular pressure or treating glaucoma

Abstract

The present invention discloses a radiofrequency ablation handle, comprising a shell and a radiofrequency ablation electrode installed in the shell, the front end of the radiofrequency ablation electrode extending out of the shell; the radiofrequency ablation electrode is cylindrical as a whole, comprising an electrode positive pole located in the center, an insulating sleeve arranged on the periphery of the electrode positive pole, and an electrode negative pole arranged on the periphery of the insulating sleeve; the electrode positive pole, the insulating sleeve, and the electrode negative pole are coaxial, and the electrode positive pole and the electrode negative pole can slide relative to each other. After the radiofrequency ablation electrode is energized, an ablation zone is generated between the electrode positive pole and the electrode negative pole, and the ablation zone is used to act on the ciliary body to reduce the production of aqueous humor; the shell is also connected to a pushing mechanism, and the pushing mechanism is used to adjust the distance between the front end of the electrode positive pole and the front end of the electrode negative pole. In the present invention, the pushing mechanism accurately adjusts the depth of the radiofrequency ablation electrode inserted into the eye to adapt to the eyeballs of different patients and achieve the purpose of precise ablation. The present invention also provides a radiofrequency ablation device that is easy to operate and use.

Description

Technical Field

[0001] The present invention relates to the technical field of medical equipment, and in particular to a radiofrequency ablation handle and a radiofrequency ablation device for reducing intraocular pressure or treating glaucoma. Background Art

[0002] Glaucoma is a group of diseases characterized by optic disc atrophy and depression, visual field defects and decreased vision. Pathologically increased intraocular pressure and insufficient blood supply to the optic nerve are the primary risk factors for its onset. The optic nerve's tolerance to pressure damage is also related to the occurrence and development of glaucoma.

[0003] Aqueous humor is secreted by the ciliary epithelium on the inner surface of the ciliary body and enters the posterior chamber. It then flows through the lens and returns to the anterior chamber through the fenestration. Aqueous humor passively exits the anterior chamber angle via two main pathways: the first is through the trabecular meshwork, passing through the inner wall of Schlemms' canal to reach the lumen, then flowing into the collecting ducts, aqueous veins, and episcleral venous circulation. The second pathway is through the iris root, the uveal plexus, and the anterior surface of the ciliary muscle, through the interfascicular connective tissue and the suprachoroidal space, and out through the sclera. Obstruction of any link in the aqueous humor circulation pathway can lead to pathological changes caused by elevated intraocular pressure, but some patients also present with normal-tension glaucoma.

[0004] Intraocular pressure (IOP), also known as intraocular pressure, is the pressure of the eye's contents against the inner wall of the eye. IOP is an independent risk factor for glaucoma, leading to further damage to the optic nerve. Controlling IOP is an economical approach.

[0005] Simply put, the most important means of treating glaucoma is to lower intraocular pressure. There are two main ways to lower intraocular pressure: one is to increase the drainage of aqueous humor in the eye; the other is to reduce the production of aqueous humor in the eye.

[0006] There are many types of surgical treatments for glaucoma, such as laser therapy, trabeculectomy, drainage devices, and MIGS.

[0007] The above-mentioned surgical procedures or equipment all have certain limitations. Common laser treatments include trabeculectomy and laser cyclophotocoagulation. Trabeculectomy means that when the laser acts on the trabecular meshwork, the trabecular meshwork contracts locally, causing the adjacent trabecular meshwork to stretch, increasing the cavities and making the aqueous humor drainage circuit smoother. However, this surgery may only be effective for a limited period of time (a few years).

[0008] Laser cyclophotocoagulation involves applying a laser to the ciliary body, killing some of the tissue and reducing aqueous humor production. However, lasers can be irritating to the eye, and controlling the area of ​​effect can be difficult. In most cases, this procedure is reserved for patients with advanced glaucoma whose intraocular pressure remains elevated despite conventional medical and / or multiple surgical treatments.

[0009] When using a drainage device to treat glaucoma, a large incision needs to be made in the eye during the implantation process.

[0010] MIGS (Minimally Invasive Glaucoma Surgery) is a minimally invasive glaucoma surgery (MIGS). Common MIGS methods include anterior chamber-trabecular MIGS drainage and filtering bleb MIGS drainage. Anterior chamber-trabecular MIGS drainage involves using a drainage tube or drainage pin to penetrate the trabecular meshwork, connecting the anterior chamber and the Schlemms' canal. Under the influence of anterior chamber pressure, aqueous humor is directed through the drainage device into the Schlemms' canal. Aqueous humor in the Schlemms' canal then circulates through the collecting duct and episcleral veins. This process reduces aqueous humor in the anterior chamber and lowers intraocular pressure. However, this drainage method has limited antihypertensive effects and is suitable for treating patients with early-stage or intermediate-stage glaucoma. Furthermore, some patients experience blockage or adhesion of the Schlemms' canal. In these cases, connecting the anterior chamber and the trabecular meshwork may not effectively lower intraocular pressure.

[0011] MIGS drainage involves surgically or by other means separating the conjunctiva or sclera to create a bleb space. A drainage tube is then passed through the sclera to penetrate the trabecular meshwork, connecting the anterior chamber and the bleb. Under the influence of anterior chamber pressure, aqueous humor is directed through the tube into the bleb space, where it is absorbed by the sclera, completing the aqueous humor circulation. This process reduces the amount of aqueous humor in the anterior chamber and lowers intraocular pressure. The effectiveness of this drainage method is directly related to the morphology of the bleb. The sclera and conjunctiva have strong regenerative abilities, and surgical creation of a bleb carries the risk of scarring, which reduces drainage effectiveness. Furthermore, the bleb's location on the ocular surface can affect the patient's appearance, leading some patients to resist this procedure.

[0012] Prior art ablation can also treat glaucoma. One approach involves using ablation electrodes to destroy the aqueous humor within the ciliary body, thereby reducing aqueous humor production and lowering intraocular pressure, ultimately treating glaucoma. However, due to varying physiological conditions, the depth of the ciliary body, sclera, and conjunctiva varies from patient to patient, making it difficult to precisely control and adjust the depth of penetration of ablation electrodes into the patient's eye.

[0013] Furthermore, in the present invention, the structures inside the eyeball are explained as follows:

[0014] Ciliary body: Located in the middle part of the uveal tract, about 6mm thick, it is the main organ for secreting aqueous humor in the eye.

[0015] Conjunctiva: The part of the eye that lies inside the eyelid and covers the sclera (the white of the eye).

[0016] Sclera: commonly known as the white of the eye, it is a milky white, opaque fibrous membrane inside the eyeball, which belongs to the fibrous membrane of the eyeball.

[0017] Aqueous humor: The anterior chamber is filled with a colorless fluid called aqueous humor. Summary of the Invention

[0018] The present invention provides a radiofrequency ablation handle and a radiofrequency ablation device for reducing intraocular pressure or treating glaucoma, which solve the problem that the depth of radiofrequency ablation electrodes penetrating into the eye cannot be adjusted.

[0019] In order to solve the above technical problems, a technical solution adopted by the present invention is to provide a radiofrequency ablation handle for reducing intraocular pressure or treating glaucoma, comprising a shell and a radiofrequency ablation electrode installed in the shell, and the front end of the radiofrequency ablation electrode extends out of the shell; the radiofrequency ablation electrode is columnar as a whole, including an electrode positive pole located in the center, an insulating sleeve arranged around the periphery of the electrode positive pole, and an electrode negative pole arranged around the periphery of the insulating sleeve; the electrode positive pole, the insulating sleeve, and the electrode negative pole are coaxial, and the distance between the front end of the electrode positive pole and the front end of the electrode negative pole is the depth of the radiofrequency ablation electrode penetrating into the eye, and the front end of the electrode negative pole stays outside the eyeball; the electrode positive pole and the electrode negative pole can slide relative to each other, and after the radiofrequency ablation electrode is energized, an ablation zone is generated between the electrode positive pole and the electrode negative pole, and the ablation zone is used to act on the ciliary body to reduce the production of aqueous humor; the shell is also connected to a pushing mechanism, and the pushing mechanism is used to adjust the distance between the front end of the electrode positive pole and the front end of the electrode negative pole.

[0020] Preferably, the pushing mechanism includes a pushing component, a pushing bracket, an elastic component and a pushing adjusting body; the pushing knob is at least partially exposed outside the shell, connected to the pushing bracket inside the shell, and can push the pushing bracket to move forward and backward; the elastic component is arranged between the pushing bracket and the inner wall of the shell, and has an elastic force to push the pushing bracket to move backward; the pushing adjusting body is connected to the rear end of the pushing bracket, and is used to adjust the pushing distance of the pushing bracket; the tail of the positive electrode is fixedly connected to the inner wall of the shell, and the tail of the negative electrode is fixedly connected to the pushing bracket.

[0021] Preferably, the pushing bracket is provided with a first fixing portion for fixing the negative electrode.

[0022] Preferably, the elastic component is a reset spring, which is sleeved on the periphery of the negative electrode, one end of the reset spring abuts against the first fixing portion, and the other end abuts against the inner wall of the shell.

[0023] Preferably, a sliding portion is provided at the rear end of the pushing bracket, and a sliding groove is correspondingly provided on the pushing adjustment body, and the sliding portion can move back and forth along the sliding groove; an adjusting ball is placed in the sliding groove, and the end of the sliding portion is in contact with the adjusting ball.

[0024] Preferably, the pushing component includes a pushing knob and a pushing screw located on one side of the pushing knob, a limiting nut is embedded in the middle portion of the pushing bracket, and the pushing screw is threadedly connected to the limiting nut.

[0025] Preferably, a second fixing portion for fixing the positive electrode is provided on the inner wall of the shell.

[0026] Preferably, the second fixing portion passes through the pushing bracket, and a strip-shaped through hole for the second fixing portion to pass through is provided on the pushing bracket.

[0027] Preferably, an adjusting ball mounting hole for placing the adjusting ball is provided on the side wall of the shell.

[0028] The present invention also provides a radiofrequency ablation device for reducing intraocular pressure or treating glaucoma, comprising the radiofrequency ablation handle for reducing intraocular pressure or treating glaucoma described above, wherein the radiofrequency ablation handle is electrically connected to an ablation host.

[0029] The beneficial effects of the present invention are as follows: the present invention discloses a radiofrequency ablation handle for reducing intraocular pressure or treating glaucoma, comprising a shell and a radiofrequency ablation electrode installed in the shell, the front end of the radiofrequency ablation electrode extending out of the shell; the radiofrequency ablation electrode is generally columnar, comprising an electrode positive electrode located in the center, an insulating sleeve arranged around the outer periphery of the electrode positive electrode, and an electrode negative electrode arranged around the outer periphery of the insulating sleeve; the electrode positive electrode, the insulating sleeve, and the electrode negative electrode are coaxial, and the electrode positive electrode and the electrode negative electrode can slide relative to each other. After the radiofrequency ablation electrode is energized, an ablation zone is generated between the electrode positive electrode and the electrode negative electrode, and the ablation zone is used to act on the ciliary body to reduce the production of aqueous humor; the shell is also connected to a pushing mechanism, which is used to adjust the distance between the front end of the electrode positive electrode and the front end of the electrode negative electrode. In the present invention, the pushing mechanism accurately adjusts the depth of the radiofrequency ablation electrode inserted into the eye to adapt to the eyeballs of different patients and achieve the purpose of precise ablation. The present invention also provides a radiofrequency ablation device for reducing intraocular pressure or treating glaucoma, which is easy to operate and use. BRIEF DESCRIPTION OF THE DRAWINGS

[0030] Figure 1is an overall schematic diagram of an embodiment of a radiofrequency ablation electrode in a radiofrequency ablation handle for reducing intraocular pressure or treating glaucoma according to the present invention;

[0031] Figure 2 is an exploded schematic diagram of an embodiment of a radiofrequency ablation electrode in a radiofrequency ablation handle for reducing intraocular pressure or treating glaucoma according to the present invention;

[0032] Figure 3 is an overall schematic diagram of another embodiment of a radiofrequency ablation electrode in a radiofrequency ablation handle for reducing intraocular pressure or treating glaucoma according to the present invention;

[0033] Figure 4 is an exploded schematic diagram of another embodiment of a radiofrequency ablation electrode in a radiofrequency ablation handle for reducing intraocular pressure or treating glaucoma according to the present invention;

[0034] Figure 5 is an overall schematic diagram of a radiofrequency ablation handle for reducing intraocular pressure or treating glaucoma according to the present invention;

[0035] Figure 6 is an exploded schematic diagram of a radiofrequency ablation handle for reducing intraocular pressure or treating glaucoma according to the present invention;

[0036] Figure 7 It is a partially enlarged schematic diagram of a radiofrequency ablation handle for reducing intraocular pressure or treating glaucoma according to the present invention;

[0037] Figure 8 is another partially enlarged schematic diagram of a radiofrequency ablation handle for reducing intraocular pressure or treating glaucoma according to the present invention;

[0038] Figure 9 is a schematic diagram of a second shell in a radiofrequency ablation handle for reducing intraocular pressure or treating glaucoma according to the present invention;

[0039] Figure 10 is a schematic diagram of a first shell in a radiofrequency ablation handle for reducing intraocular pressure or treating glaucoma according to the present invention;

[0040] Figure 11 It is a partial cross-sectional view of a radiofrequency ablation handle for reducing intraocular pressure or treating glaucoma according to the present invention. DETAILED DESCRIPTION

[0041] To facilitate understanding of the present invention, the present invention will be described in more detail below with reference to the accompanying drawings and specific embodiments. Preferred embodiments of the present invention are shown in the accompanying drawings. However, the present invention can be implemented in many different forms and is not limited to the embodiments described in this specification. Rather, these embodiments are provided to provide a more thorough and comprehensive understanding of the disclosure of the present invention.

[0042] It should be noted that, unless otherwise defined, all technical and scientific terms used in this specification have the same meanings as those commonly understood by those skilled in the art to which this invention pertains. The terms used in this specification are intended solely for the purpose of describing specific embodiments and are not intended to limit the invention. The term "and / or" as used in this specification includes any and all combinations of one or more of the associated listed items.

[0043] like Figures 1 to 11 As shown, the radiofrequency ablation handle for reducing intraocular pressure or treating glaucoma includes a shell 1 and a radiofrequency ablation electrode 2 installed in the shell 1. The front end of the radiofrequency ablation electrode 2 extends out of the shell 1 to facilitate insertion into the eye.

[0044] Combine Figure 1 and Figure 2 , as the first embodiment of the radiofrequency ablation electrode 2 in the present invention.

[0045] The RF ablation electrode 2 is generally cylindrical and includes a centrally located positive electrode 201, an insulating sleeve 202 surrounding the positive electrode 201, and a negative electrode 203 surrounding the insulating sleeve 202. The positive electrode 201, insulating sleeve 202, and negative electrode 203 are coaxial. When the RF ablation electrode 2 is energized, an ablation zone is generated between the positive electrode 201 and the negative electrode 203. This ablation zone acts on the ciliary body to reduce aqueous humor production. For eyes with shallow anterior chambers, ablation with the RF ablation electrode 2 can cause the ciliary body to contract, increasing the gap between the lens and the ciliary RF ablation electrode 2, reducing ciliary block, lowering the trans-lens pressure gradient, and deepening the anterior chamber.

[0046] The radiofrequency ablation electrode 2 in the present invention can easily enter the narrow space of the eye to ablate the ciliary body, producing a controllable small ablation area; the ablation zone is concentrated between the electrode positive pole 201 and the electrode negative pole 203. The insertion position of the radiofrequency ablation electrode 2 determines the ablation position, which can be the tissue surface or a specific position inside the tissue.

[0047] Furthermore, the positive electrode 201 has excellent biocompatibility and good electrical conductivity. The positive electrode 201 can be made of stainless steel, such as 2Cr13, 1Cr13, 1Cr18Ni9, SUS304(L), SUS316(L), or SUS430; titanium alloys, such as TC4; or conductive metal materials, such as pure titanium, tungsten steel, pure tungsten, tungsten carbide, platinum, or platinum-iridium alloys.

[0048] Preferably, the positive electrode 201 is cylindrical as a whole, and the length of the positive electrode 201 is 3 mm to 50 mm, and the diameter is 0.1 mm to 1 mm.

[0049] Preferably, in order to facilitate the insertion of the tissue, the front end of the electrode positive electrode 201 is processed into a first conical tip 2011. The first conical tip 2011 can be a cone, a triangular pyramid, a quadrangular pyramid or other conical shapes. Figure 1 In the embodiment, the first conical tip 2011 is conical. The first conical tip 2011 can be made into a sharp cone by grinding or heating, melting and drawing, so that the positive electrode 201 can easily pierce the eye and reach the target tissue during puncture.

[0050] Furthermore, the insulating sleeve 202 is a cylindrical sleeve as a whole, and has good biocompatibility and insulation. The material of the insulating sleeve can be Parylene / silicone / PTFE / ABS / PI / PET, or the insulating coating can be made by vapor deposition method, and the material of the insulating coating is Parylene.

[0051] Furthermore, the negative electrode 203 has excellent biocompatibility and good electrical conductivity. The negative electrode 203 can be made of stainless steel, such as 2Cr13, 1Cr13, 1Cr18Ni9, SUS304(L), SUS316(L), or SUS430; titanium alloys, such as TC4; or conductive metal materials, such as pure titanium, tungsten steel, pure tungsten, platinum, or platinum-iridium alloys.

[0052] The length of the negative electrode 203 is 3 mm to 50 mm, the inner diameter is 0.1 mm to 1.1 mm, and the outer diameter is 0.2 mm to 1.5 mm.

[0053] Furthermore, in the present invention, the length of the positive electrode 201 is greater than the length of the insulating sleeve 202 , and the length of the insulating sleeve 202 is greater than the length of the negative electrode 203 .

[0054] The insulating sleeve 202 extends from the tail of the first conical tip 2011 toward the tail of the electrode positive pole 201, and the tail of the insulating sleeve 202 does not overlap with the tail of the electrode positive pole 201, that is, the tail of the electrode positive pole 201 is to be exposed; the tail of the electrode positive pole 201 must remain conductive and be used to be electrically connected to the RF positive signal cable 10; the tail of the electrode negative pole 203 is electrically connected to the RF negative signal cable 9.

[0055] Preferably, the insulating sleeve 202 is fixedly connected to the positive electrode 201. The insulating sleeve 202 can be directly sleeved onto the positive electrode 201 by interference fit; can also be sleeved onto the positive electrode 201 by gluing; or can be sleeved onto the positive electrode 201 and fixed to the positive electrode 201 by heat shrinking or other methods; or a parylene coating can be deposited on the positive electrode 201 by vapor deposition, and a shielding layer can be formed at the tip and tail of the positive electrode 201 before the coating is deposited, and the shielding layer can be removed after the coating is deposited; or, after the coating is deposited, the coating at the tip and tail of the positive electrode 201 can be stripped by grinding, scraping, or laser stripping to achieve the purpose of insulating the middle of the positive electrode 201 and conducting at both ends.

[0056] Furthermore, in the present invention, the first conical tip 2011 at the front end of the positive electrode 201 pierces the conjunctiva and sclera and enters the ciliary body; at the same time, due to the thin wall thickness of the insulating sleeve 202, the insulating sleeve 202 also enters the ciliary body; the wall thickness of the negative electrode 203 is relatively large, and it stays outside the eyeball and does not enter the eyeball; therefore, the process of the radiofrequency ablation electrode 2 piercing the human eye is smooth and labor-saving, without steps, and there is no jamming during the insertion process.

[0057] In addition, the first conical tip 2011 of the positive electrode 201 is a sharp point for discharge. The current density released by the first conical tip 2011 is extremely large, and the ablation site is concentrated at the position of the first conical tip 2011. Since the area of ​​the negative electrode 203 is also large, the current can be stably transmitted through the human eye tissue to the negative electrode 203 to form a loop. Therefore, the ablation effect of the radiofrequency ablation electrode 2 is also excellent.

[0058] In the present invention, the length between the tip of the first conical tip 2011 on the RF ablation electrode 2 and the front end of the electrode cathode 203 represents the penetration depth of the RF ablation electrode 2 into the eye. Due to varying physiological conditions, the thickness of the sclera, conjunctiva, and ciliary body varies across patients. From the perspective of ocular anatomy, the precise penetration depth of the RF ablation electrode 2 directly impacts the ablation location, significantly affecting the ultimate treatment outcome.

[0059] Preferably, the positive electrode 201 and the negative electrode 203 can slide relative to each other to adjust the depth of penetration into the eye to adapt to the eyeballs of different patients and achieve the purpose of precise ablation.

[0060] Furthermore, the positive electrode 201 and the negative electrode 203 can slide relative to each other, and because the positive electrode 201 and the insulating sleeve 202 are fixedly connected, the insulating sleeve 202 and the negative electrode 203 can slide relative to each other.

[0061] In the present invention, the distance between the front end of the electrode positive pole 201 and the front end of the electrode negative pole 203 is adjusted by the pushing mechanism 3 in the radiofrequency ablation handle, that is, the depth of the electrode positive pole 201 penetrating into the eye can be adjusted by the pushing mechanism 3. The adjustment principle is described below.

[0062] Further, combined Figures 3 and 4 In the present invention, the second embodiment of the radiofrequency ablation electrode 2 is provided. Based on the first radiofrequency ablation electrode 2, the front end of the negative electrode 203 is further provided with a negative electrode disk 2031, and the shape of the negative electrode disk 2031 can be circular, triangular, square, etc.

[0063] Preferably, the negative electrode disk 2031 is in the shape of a flat disc. Of course, it can also be a patterned disc, a hollow disc, or a special-shaped disc. The negative electrode disk 2031 can increase the return area of ​​the current, so that the ablation location is concentrated at the tip of the positive electrode 201. Secondly, the negative electrode disk 2031 has a large cross-section and can also serve as a limiter to ensure that the negative electrode 203 does not penetrate the eyeball during the operation, preventing the radiofrequency ablation electrode 2 from piercing the eyeball.

[0064] Further, combined Figures 5 to 11 In the present invention, the radiofrequency ablation handle includes a housing 1, which is in the shape of a straight rod, or can be large in the middle and small at both ends, or large at both ends and small in the middle, suitable for single-handed operation.

[0065] The material of the housing 1 can be ABS, POM, PEEK, PVC, PET, nylon, polymer materials, modified engineering plastics, zinc alloy, aluminum alloy, magnesium-aluminum alloy, stainless steel, copper, iron, etc.

[0066] Furthermore, the housing 1 includes a first housing 101 and a second housing 102 . A tapered portion 1014 is provided at the front end of the first housing 101 , and the front end of the radiofrequency ablation electrode 2 extends out of the tapered portion 1014 .

[0067] The first shell 101 and the second shell 102 are detachably connected, and the detachable connection can be achieved by means of a snap connection, a threaded connection, or the like.

[0068] In the present invention, a plurality of receiving portions 1015 are provided on the edge of the first shell 101 , and a plurality of snap-fit ​​portions 1021 are correspondingly provided on the edge of the second shell 102 . The snap-fit ​​portions 1021 can be snapped into the receiving portions 1015 to fix the first shell 101 and the second shell 102 .

[0069] Preferably, the first shell 101 and the second shell 102 may also be fixedly connected, for example, by gluing, ultrasonic welding, laser welding or other fixing methods.

[0070] Preferably, a first positioning post 1016 is provided on the inner wall of the first housing 101, and a second positioning post 1022 is correspondingly provided on the inner wall of the second housing 102. The second positioning post 1022 is further provided with a positioning hole 1023, so that the first positioning post 1016 can be inserted into the positioning hole 1023. In this way, the first housing 101 and the second housing 102 can be pre-positioned when connected.

[0071] Preferably, the housing 1 is further connected to a stress relief tube 11, the front end of which is snap-fitted into the interior of the housing 1. A clamping block 14 is provided on either side of the front end of the stress relief tube 11. The rear ends of both the first housing 101 and the second housing 102 are provided with mounting slots 12, each of which contains a clamping slot 13 corresponding to the clamping block 14. The front end of the stress relief tube 11 can be installed in one of the mounting slots 12, with the clamping block 14 snapping into the clamping slot 13. Once the first housing 101 and the second housing 102 are connected, the stress relief tube 11 is simultaneously secured.

[0072] The stress release tube 11 plays a role in protecting the RF positive signal cable 9 and the RF negative signal cable 10, and will not cause the RF positive signal cable 9 and the RF negative signal cable 10 to break due to bending the stress release tube 11; the RF positive signal cable 9 and the RF negative signal cable 10 are used to electrically connect the electrode positive electrode 201 and the electrode negative electrode 203 respectively.

[0073] In the present invention, the pushing mechanism 3 includes a pushing component 4 , a pushing bracket 5 , an elastic component 6 and a pushing adjusting body 7 .

[0074] Pushing component 4: The pushing component 4 is at least partially exposed outside the housing 1 and is connected to the pushing bracket 5 inside the housing 1, pushing the pushing bracket 5 back and forth. Specifically, the pushing component 4 includes a pushing knob 41 and a pushing screw 42 located on one side of the pushing knob 41. The pushing knob 41 is located on the side near the first housing 101 and is completely exposed outside the first housing 101. The pushing knob 41 is circular in shape. A pushing groove 1012 is provided in the side wall of the first housing 101 along the front-to-back direction. The pushing screw 42 passes through the pushing groove 1012 and connects to the pushing bracket 5.

[0075] Pushing bracket 5: The pushing bracket 5 is a flat, plate-like structure. A stop nut 8 is embedded in the middle of the pushing bracket 5, and a pushing screw 42 is threadedly connected to the stop nut 8. When the pushing knob 41 is turned, the pushing screw 42 rotates coaxially, continuously screwing into the stop nut 8. When the pushing knob 41 contacts the outer surface of the first housing 101, the pushing knob 41 cannot move forward or backward, thus securing the pushing knob 41.

[0076] The tail of the negative electrode 203 is fixedly connected to the pushing bracket 5, and a first fixing portion 51 for fixing the negative electrode 203 is provided on the pushing bracket 5. The first fixing portion 51 is located on the side of the pushing bracket 5 away from the pushing knob 41 and is provided at the front end of the pushing bracket 5; the tail of the negative electrode 203 can be fixed in the electrode fixing hole on the first fixing portion 51 by embedding, welding, etc., so that when the pushing bracket 5 moves forward and backward, it also drives the negative electrode 203 to move forward and backward.

[0077] The material of the pushing bracket 5 can be ABS, POM, PEEK, PVC, PET, nylon, polymer materials, modified engineering plastics, zinc alloy, aluminum alloy, magnesium aluminum alloy, stainless steel, copper, iron, etc.

[0078] Elastic component 6: The elastic component 6 is disposed between the push bracket 5 and the inner wall of the housing 1 and exerts a force to push the push bracket 5 backward. Preferably, the elastic component 6 is a return spring, which is sleeved around the outer periphery of the negative electrode 203. One end of the return spring abuts against the first fixing portion 51, and the other end abuts against the inner wall of the housing 1. Specifically, the other end of the return spring abuts against the inner wall of the tapered portion 1014.

[0079] The tail of the positive electrode 201 is fixedly connected to the inner wall of the housing 1. The inner wall of the housing 1 is provided with a second fixing portion 1011 for fixing the positive electrode 201. The second fixing portion 1011 is specifically provided on the inner wall of the first housing 101. The tail of the positive electrode 201 can be fixed in the electrode fixing hole of the second fixing portion 1011 by embedding, welding, etc., that is, the positive electrode 201 is fixed relative to the negative electrode 203.

[0080] Preferably, the second fixing portion 1011 passes through the pushing bracket 5 , and a strip-shaped through hole 52 is provided on the pushing bracket 5 for the second fixing portion 1011 to pass through, so that the pushing bracket 5 will not interfere with the second fixing portion 1011 when moving forward and backward.

[0081] Pushing adjustment body 7: The pushing adjustment body 7 is connected to the rear end of the pushing bracket 5 and is used to adjust the pushing distance of the pushing bracket 5. Specifically, the rear end of the pushing bracket 5 is provided with a sliding portion 53 with a T-shaped cross-section. The pushing adjustment body 7 is correspondingly provided with a sliding groove 71. The shape of the sliding groove 71 is adapted to the shape of the sliding portion 53, and the sliding portion 53 can move back and forth along the sliding groove 71.

[0082] An adjusting ball 72 is accommodated in the slide groove 71 , and an end portion of the sliding portion 53 contacts the adjusting ball 72 . A touch panel 54 for contacting the adjusting ball 72 is also provided at the end portion of the sliding portion 53 .

[0083] Preferably, an adjusting ball mounting hole 1013 for placing the adjusting ball 72 is provided on the side wall of the housing 1 ; specifically, the adjusting ball mounting hole 1013 is provided on the side wall of the first housing 101 .

[0084] exist Figure 11 When the adjusting ball 72 is not placed in the slide groove 71, the push bracket 5, under the action of the return spring, the touch panel 54 on the sliding part 53 contacts the rear end inner wall of the slide groove 71. At this time, the adjusting ball mounting hole 1013 is also blocked by the sliding part 53, and the adjusting ball 72 cannot be placed; when the pushing knob 41 is pushed to drive the pushing bracket 5 to move forward and the adjusting ball mounting hole 1013 is not blocked, the adjusting ball 72 can be placed in the slide groove 71, so that the touch panel 54 contacts the adjusting ball 72.

[0085] Preferably, the adjustment sphere 72 may have different diameters, and the depth at which the positive electrode 201 penetrates into the eye can be adjusted by replacing the adjustment sphere 72 with different diameters.

[0086] Combine Figure 11 ,exist Figure 11 In the figure, L4 = L1 + L2 + L3, where L1 is the distance from the front end of the positive electrode 201 to the front end of the negative electrode 203, and L1 is the depth of the positive electrode 201 penetrating the eyeball; L2 is the distance from the front end of the negative electrode 203 to the touch panel 54, and the value of L2 is fixed; L3 is the diameter of the adjustment sphere 72; and L4 is the distance from the front end of the positive electrode 201 to the inner wall of the rear end of the chute 71, and the value of L4 is fixed. Because the values ​​of L4 and L2 are fixed, changing the value of L3 will also change L1. This means that changing the diameter of the adjustment sphere 72 can adjust the depth of the positive electrode 201 penetrating the eyeball. Adjusting the depth of the positive electrode 201 penetrating the eyeball by replacing the adjustment sphere 72 is convenient, fast, and highly accurate, and can accurately adjust the depth of the positive electrode 201 penetrating the eyeball within a very small range.

[0087] For example, when the thickness of the sclera + conjunctiva is 1.5 mm (i.e., L1=1.5 mm), the adjusting sphere 72 with a diameter of 3.0 mm is selected, i.e., L3=L4-L2-1.5=3.0 mm; when the thickness of the sclera + conjunctiva is 1.4 mm, the adjusting sphere 72 with a diameter of 3.1 mm is selected, i.e., L3=L4-L2-1.4=3.1 mm; when the thickness of the sclera + conjunctiva is 1.6 mm, the adjusting sphere 72 with a diameter of 2.9 mm is selected, i.e., L3=L4-L2-1.6=2.9 mm.

[0088] The present invention also provides a radiofrequency ablation device for reducing intraocular pressure or treating glaucoma, comprising the radiofrequency ablation handle described above, which is electrically connected to an ablation host. The ablation host is electrically connected to the radiofrequency ablation handle via a radiofrequency signal cable, which includes a positive radiofrequency signal cable 10 and a negative radiofrequency signal cable 9.

[0089] The RF ablation device is used as follows: Sterilize the RF ablation handle using a variety of methods, including gas sterilization (ethylene oxide, formaldehyde, ozone), radiation sterilization (microwave, ultraviolet (UV), X-rays, and gamma rays). Connect the RF ablation handle to the ablation host, which transmits current to the RF ablation electrode 2 on the RF ablation handle via the RF signal cable.

[0090] Before the start of the radiofrequency ablation surgery, the patient's eyes are filmed, the thickness of the sclera and conjunctiva outside the ciliary body is measured, the insertion depth S of the positive electrode 201 is determined, and the adjustment ball 72 of the corresponding size is selected according to the insertion depth S.

[0091] Loosen the push knob 41 to allow it to move forward; since the push knob 41 is connected to the push bracket 5, the push bracket 5 also moves forward with the push knob 41; in the process of the push bracket 5 moving forward, the adjustment ball mounting hole 1013 on the first shell 101 is exposed; put the adjustment ball 72 into the adjustment ball mounting hole 1013, stop pushing the push knob 41, and the push bracket 5 slides backward under the action of the elastic component 6 (reset spring), and the touch panel 54 on the sliding part 53 is against the adjustment ball 72. At this time, tighten the push knob 41 and the push knob 41 is fixed; the operator can insert the radiofrequency ablation electrode 2 into the patient's eye and drive the ablation host to work. The ablation host outputs current to the electrode positive pole 201, and the current returns to the electrode negative pole 203 through the ciliary body tissue. The ablation effect is mainly concentrated on the first conical tip 2011. In the ciliary body, the ablation zone produced by the radiofrequency ablation electrode 2 destroys the aqueous humor tissue of the ciliary body, thereby reducing the production of aqueous humor in the ciliary body, thereby achieving the purpose of lowering intraocular pressure and treating glaucoma. This method has the same effect on open-angle glaucoma and angle-closure glaucoma.

[0092] It can be seen that the present invention discloses a radiofrequency ablation handle for reducing intraocular pressure or treating glaucoma, including a shell and a radiofrequency ablation electrode installed in the shell, the front end of the radiofrequency ablation electrode extends out of the shell; the radiofrequency ablation electrode is cylindrical as a whole, including an electrode positive pole located in the center, an insulating sleeve arranged around the outer periphery of the electrode positive pole, and an electrode negative pole arranged around the outer periphery of the insulating sleeve; the electrode positive pole, the insulating sleeve, and the electrode negative pole are coaxial, and the electrode positive pole and the electrode negative pole can slide relative to each other. After the radiofrequency ablation electrode is energized, an ablation zone is generated between the electrode positive pole and the electrode negative pole, and the ablation zone is used to act on the ciliary body to reduce the production of aqueous humor; the shell is also connected to a pushing mechanism, which is used to adjust the distance between the front end of the electrode positive pole and the front end of the electrode negative pole. In the present invention, the pushing mechanism accurately adjusts the depth of the radiofrequency ablation electrode inserted into the eye to adapt to the eyeballs of different patients and achieve the purpose of precise ablation. The present invention also provides a radiofrequency ablation device for reducing intraocular pressure or treating glaucoma, which is easy to operate and use.

[0093] The above descriptions are merely embodiments of the present invention and are not intended to limit the patent scope of the present invention. Any equivalent structural transformations made using the contents of the present invention's description and drawings, or directly or indirectly applied to other related technical fields, are also included in the patent protection scope of the present invention.

Claims

1. A radiofrequency ablation handle for reducing intraocular pressure or treating glaucoma, characterized by: The invention comprises a shell and a radiofrequency ablation electrode installed in the shell, wherein the front end of the radiofrequency ablation electrode extends out of the shell; the radiofrequency ablation electrode is generally columnar, comprising a positive electrode located in the center, an insulating sleeve arranged around the positive electrode, and a negative electrode arranged around the insulating sleeve; the positive electrode, the insulating sleeve, and the negative electrode are coaxial, the distance between the front end of the positive electrode and the front end of the negative electrode is the depth of the radiofrequency ablation electrode inserted into the eye, and the front end of the negative electrode stays outside the eyeball; the positive electrode and the negative electrode are relatively slidable, and when the radiofrequency ablation electrode is energized, an ablation zone is generated between the positive electrode and the negative electrode, and the ablation zone is used to act on the ciliary body to reduce the production of aqueous humor; The housing is also connected to a pushing mechanism, the pushing mechanism for adjusting the distance between the front end of the positive electrode to the front end of the negative electrode; The pushing mechanism includes a pushing component, a pushing bracket, an elastic component and a pushing adjustment body; the pushing component includes a pushing knob, which is at least partially exposed outside the shell and is connected to the pushing bracket inside the shell, and can push the pushing bracket to move forward and backward; the elastic component is arranged between the pushing bracket and the inner wall of the shell, and has an elastic force that pushes the pushing bracket to move backward; the pushing adjustment body is connected to the rear end of the pushing bracket, and is used to adjust the pushing distance of the pushing bracket; the tail of the positive electrode is fixedly connected to the inner wall of the shell, and the tail of the negative electrode is fixedly connected to the pushing bracket; A sliding portion is provided at the rear end of the pushing bracket, and a sliding groove is correspondingly provided on the pushing adjustment body, and the sliding portion can move back and forth along the sliding groove; an adjusting ball is placed in the sliding groove, and the end of the sliding portion is in contact with the adjusting ball; the adjusting balls have different diameters, and the depth of the electrode positive pole inserted into the eye can be adjusted by replacing the adjusting balls with different diameters.

2. The radiofrequency ablation handle for reducing intraocular pressure or treating glaucoma according to claim 1, characterized in that: The pushing bracket is provided with a first fixing portion for fixing the negative electrode.

3. The radiofrequency ablation handle for reducing intraocular pressure or treating glaucoma according to claim 2, characterized in that: The elastic component is a reset spring, which is sleeved on the periphery of the negative electrode. One end of the reset spring abuts against the first fixing portion, and the other end abuts against the inner wall of the shell.

4. The radiofrequency ablation handle for reducing intraocular pressure or treating glaucoma according to claim 1, characterized in that: The pushing component further includes a pushing screw located on one side of the pushing knob, a limiting nut is embedded in the middle portion of the pushing bracket, and the pushing screw is threadedly connected to the limiting nut.

5. The radiofrequency ablation handle for reducing intraocular pressure or treating glaucoma according to claim 1, characterized in that: A second fixing portion for fixing the positive electrode is provided on the inner wall of the shell.

6. The radiofrequency ablation handle for reducing intraocular pressure or treating glaucoma according to claim 5, characterized in that: The second fixing portion passes through the pushing bracket, and the pushing bracket is provided with a strip-shaped through hole for the second fixing portion to pass through.

7. The radiofrequency ablation handle for reducing intraocular pressure or treating glaucoma according to claim 1, characterized in that: An adjusting ball mounting hole for placing the adjusting ball is provided on the side wall of the shell.

8. A radiofrequency ablation device for reducing intraocular pressure or treating glaucoma, characterized by: The invention comprises a radiofrequency ablation handle for reducing intraocular pressure or treating glaucoma according to any one of claims 1 to 7, wherein the radiofrequency ablation handle for reducing intraocular pressure or treating glaucoma is electrically connected to an ablation host.

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