A cosmetic composition with soothing effect and its preparation method and application
By adopting a specific proportional and combination of multiple components in cosmetics, a cosmetic composition is formed, which solves the problem of soothing effects in the existing technology single or improper composition. Essence
Patent Information
- Application Number
- CN202211510556.6
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- Filing Date
- 2022-11-29
- Publication Date
- 2025-01-28
- Estimated Expiration
- 2042-11-29
AI Technical Summary
The existing soothing cosmetics have single ingredients or improper ingredient matching, which leads to aggravated skin sensitivity and cannot quickly and effectively soothe sensitive skin.
A cosmetic composition, including emulsifier, moisturizer, thickener, chelating agent, moisturizing agent, emulsifier, neutralizer, antibacterial agent, skin conditioning agent and other ingredients. Cosmetics with soothing effects.
It significantly improves the soothing effect of cosmetics composition on sensitive skin, reduces the probability of skin erythema and red blood, forms a protection barrier, and improves the effect of stability.
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Abstract
Description
Technical Field
[0001] The present invention relates to the technical field of cosmetics, and in particular to a cosmetic composition with soothing effect, a preparation method and application thereof. Background Art
[0002] The human skin is the largest organ in the human body and is the first line of defense for the human body. The human skin contains abundant sensory nerve fibers, which allow the central nervous system to detect the condition of the skin at any time and respond to various stimuli, such as physical factors such as climate change, air pollution, ultraviolet radiation, chemical factors such as the use of bad cosmetics, excessive "acid washing", and internal factors such as stress, emotions, and endocrine disorders, thus serving as the "first barrier" to protect the human body. Therefore, protecting the skin is extremely important to the human body.
[0003] With the intensification of environmental pollution, the abuse of cosmetics, and high stress in life, sensitive skin is becoming more and more common. Sensitive skin is a sub-healthy state. The natural barrier of the skin is damaged and the self-defense ability is reduced, which makes it easy for external irritants to penetrate, enhance the transmission of skin sensory nerve signals, reduce the tolerance threshold, and overreact to weak external stimuli, activating the skin's immune response, leading to vascular expansion and the release of inflammatory factors. The skin is prone to subjective symptoms such as burning, stinging, itching and tightness, with or without objective signs such as erythema, scaling, and capillary dilation. Therefore, anti-allergic and soothing cosmetics are increasingly needed by people with allergic skin.
[0004] Existing soothing cosmetics either have a single ingredient, which has a relatively simple soothing effect on the skin; or have many ingredients, which are easy to be improperly mixed, which will cause irritation to the skin and aggravate skin sensitivity, and cannot soothe the skin quickly and effectively. Summary of the invention
[0005] In order to obtain cosmetics that can safely and effectively soothe sensitive skin, the present application provides a cosmetic composition with soothing effect, a preparation method and application thereof.
[0006] In a first aspect, the present application provides a cosmetic composition, which adopts the following technical solution:
[0007] A cosmetic composition, comprising the following raw materials in parts by weight: 1-1.4 parts of an emulsifier, 5-6.5 parts of an emollient, 0.24-0.28 parts of a thickener, 0.01-0.03 parts of a chelating agent, 7-9 parts of a moisturizer, 0.04-0.06 parts of an emulsion stabilizer, 0.25-0.29 parts of a neutralizer, 0.9-1.3 parts of an antibacterial agent, 2.2-2.4 parts of a skin conditioner, and 75-85 parts of deionized water;
[0008] Taking the skin conditioner as a benchmark, the skin conditioner includes the following raw materials in parts by weight: 0.0008-0.0012 parts of inonotus birch extract, 1.2-1.8 parts of peony root extract, 0.15-0.25 parts of saffron 360° soothing factor, 0.15-0.25 parts of kava extract, and 0.15-0.25 parts of oat kernel extract.
[0009] By adopting the above technical solution, the peony root extract can inhibit elastase, eliminate free radicals, inhibit the generation of nitrogen oxides, and increase the activity of tissue proteases, and work together with the birch inonotus extract to activate epidermal cells and increase the generation of collagen, thereby improving the barrier function of the skin and the ability of the skin to resist external environmental stimuli, thereby reducing the occurrence of skin allergies and irritations;
[0010] Kava extract can not only inhibit nerve receptors, but also inhibit nerve transmission after nerve receptors are activated. Taking tumor necrosis factor-α as an example, TNF-α is a major inflammatory cell signaling molecule. Standard drugs for some autoimmune diseases include controlling TNF-α. Several kava piperolactones contained in kava extract can control TNF-α to a certain extent, thereby improving the anti-inflammatory properties of the cosmetic composition. In addition, it can work together with the rich polyphenol components in birch fungus extract and peony root extract to block the occurrence of cell inflammation, reduce the occurrence of inflammatory immune reactions and the reaction of skin neurodermatitis, improve the redness and itching symptoms of allergic skin, and thus improve the soothing effect of the cosmetic composition on the skin; at the same time, kava extract, oat kernel extract and saffron 360° soothing factor work together to eliminate NFKB, the headquarters of sensitive redness stimuli. NFKB is the master switch responsible for leading IL-1, TNF-α and other stimuli, which reduces the transmission of skin sensory nerve signals and increases the tolerance threshold, reduces the allergic reactions such as erythema and bloodshot caused by external environmental stimuli, and further enhances the soothing effect of the cosmetic composition.
[0011] At the same time, through the combined action of saffron 360° soothing factor and oat kernel extract, a long-lasting moisturizing effect on the skin can be achieved, thereby forming a long-lasting protective barrier on the skin surface, reducing the skin's excessive reaction to external environmental stimuli, promoting the skin's absorption of various functional ingredients in the cosmetic composition, brightening the skin tone, thereby forming a cosmetic composition repair system that has a positive cycle effect on the skin, and comprehensively and multi-angle enhancing the soothing effect of the cosmetic composition on sensitive skin.
[0012] Optionally, based on the skin conditioner, the skin conditioner also includes 0.15-0.25 parts of allantoin and 0.15-0.25 parts of Deminshu.
[0013] By adopting the above technical scheme, on the one hand, allantoin has the effects of moisturizing, repairing, and promoting cell regeneration, which can increase the water absorption capacity of the outermost layer of the skin and promote cell regeneration, and can make the skin smooth and plump; and, allantoin has a unique keratin-dissolving property, so it has the effect of softening keratin, thereby restoring moisture to the skin and increasing skin elasticity; enhancing skin immunity, improving the barrier function of the skin's natural acid film, and preventing and improving skin problems; on the other hand, Deminshu contains natural oat derivatives, which can reduce skin damage induced by free radicals and has a calming and soothing effect on the skin; at the same time, allantoin and Deminshu work together to further enhance the skin's natural barrier function while enhancing skin immunity, so that soothing cosmetics can achieve the effect of both repairing and strengthening, and then work together with other ingredients in skin conditioners to promote the skin to form a healthy state of positive circulation, and improve the soothing effect and stabilizing effect of the cosmetic composition on the skin.
[0014] Optionally, the weight proportions of the skin conditioner, emollient and moisturizer are 1:(2.4-2.6):(3.4-3.6).
[0015] By adopting the above technical scheme, the selection of the above ingredients and proportions has set the tone for the efficacy of the cosmetic composition. In the absence of new ingredients, the soothing effect of the cosmetic composition is generally difficult to break through the limitations of the formula and further improve. In the process of continuous exploration, the applicant found that when the mass ratio of skin conditioners, emollients and moisturizers is 1: (2.4-2.6): (3.4-3.6), the facial barrier, allergic symptoms and skin condition are further balanced, thereby reducing skin allergies and maintaining a good skin condition, further improving the soothing effect of the cosmetic composition on the skin.
[0016] Optionally, based on the emollient, the emollient includes 1.2-1.8 parts of 5# viscous silicone oil, 1.6-2.4 parts of CETIOL CC, 1.6-2.4 parts of synthetic squalane, and 0.1-0.12 parts of prickle fruit oil.
[0017] By adopting the above technical scheme, 5# sticky silicone oil has low surface tension, which can make other components in the cosmetic composition easily spread into a thin film on the skin without stickiness; it works together with CETIOL CC to moisturize the skin while further reducing the greasy burden of cosmetics on the skin; the addition of synthetic squalane can promote the opening of skin pores, and the addition of Yunnan green thorn fruit has a significant penetration-promoting effect on the skin. The use of the two together can accelerate the skin's absorption of skin conditioning ingredients in cosmetics, improve skin ability, and achieve an efficient soothing effect on the skin; at the same time, CETIOL CC and synthetic squalane work together to integrate with the human body's own sebum membrane to form a natural barrier on the skin surface, thereby protecting the skin from external environmental stimulation after using soothing cosmetics, thereby enhancing the stabilizing effect of soothing cosmetics.
[0018] Optionally, based on the moisturizer, the moisturizer includes 4.5-5.5 parts of glycerin, 0.008-0.12 parts of HA macromolecules, and 2.5-3.5 parts of DPG.
[0019] By adopting the above technical solutions, glycerin, HA macromolecules and DPG can increase the softness of the skin and form an invisible protective film on the skin surface to isolate the outside air from the skin and reduce the negative impact of irritants in the external environment on the skin; moreover, HA macromolecules can bind to receptors on the cell surface to produce defensins, regulate the activity of immune cells, form cell coats, and protect cells, thereby further achieving the soothing effect of skin conditioners on the skin; finally, the addition of moisturizers can also delay the drying and cracking of cosmetics due to water evaporation, thereby extending the life of the product.
[0020] Optionally, based on the emulsifier, the emulsifier is compounded by MONTANOV 68MB and Top-care GMS165 in a weight ratio of 1:(0.8-1.2).
[0021] By adopting the above technical scheme, on the one hand, MONTANOV 68MB, as a water-in-oil type nonionic sugar-based emulsifier, uses polysaccharides to replace the active ethoxylated groups of traditional nonionic surfactants, so that the emulsifier has mild properties and reduces the probability of allergic reactions in people with sensitive skin; on the other hand, Top-care GMS 165 is a high-quality and efficient nonionic water-in-oil emulsifier, which has good electrolyte resistance, wide compatibility and excellent emulsification stability, and can promote the skin's absorption of effective ingredients in cosmetics; in the oil-water system, it utilizes its both hydrophilic and lipophilic characteristics to enable the product to form a uniform emulsified system at low concentrations, and is used in conjunction with MONTANOV 68MB to significantly improve the uniformity and mildness of the cosmetic composition.
[0022] Optionally, based on the antibacterial agent, the antibacterial agent is compounded by cinnamaldehyde and hexylene glycol in a weight ratio of 1: (0.8-1.2).
[0023] By adopting the above technical solution, the addition of antibacterial agents can effectively extend the shelf life of cosmetics and avoid contamination during use. Xinxian ketone is a natural plant extract with antioxidant and soothing effects, and has excellent stability in high and low pH and temperature ranges. It can also be used in cosmetics as a substitute for traditional preservatives and has a preservative and synergistic effect; Xinxian ketone and hexanediol are compounded to achieve a synergistic preservative effect; in addition, the antibacterial system obtained by compounding Xinxian ketone and hexanediol has a significantly reduced instability coefficient, which can effectively avoid the irritation and damage of traditional preservatives to the skin. Compared with traditional preservative ingredients, it is safer and milder, and has antioxidant effects while reducing allergenic irritation, making it more suitable for sensitive and fragile skin.
[0024] Optionally, the neutralizing agent is arginine.
[0025] By adopting the above technical solution, arginine has low hazard and high safety, and can replace neutralizers such as triethanolamine, aminomethyl propanol and sodium hydroxide. After being added to the cosmetic composition, it can reduce its irritation to sensitive skin and improve the soothing effect of the cosmetic.
[0026] In a second aspect, the present application provides a method for preparing a cosmetic composition, using the following technical solution:
[0027] A method for preparing a cosmetic composition comprises the following steps:
[0028] Step 1, mixing an emulsifier and an emollient, heating, and stirring to obtain an oil phase mixture;
[0029] Step 2, mixing the thickener with deionized water, adding the chelating agent, stirring, and then adding the moisturizer and the emulsion stabilizer, heating, and stirring to obtain an aqueous phase mixture;
[0030] Step 3, stirring and homogenizing the oil phase mixture obtained in step 1, adding the water phase mixture, heating, and continuing to homogenize to obtain a homogenous emulsified mixture;
[0031] Step 4: Cool the homogenized emulsified mixture, add a neutralizer, then add an antibacterial agent and a skin conditioner, stir, and cool to obtain a cosmetic composition.
[0032] By adopting the above technical scheme, the raw materials are mixed in batches and fully mixed, so that the raw materials can be fully coordinated and used to play a role, thereby preparing a cosmetic composition. The above preparation method is simple, efficient and convenient for industrial production.
[0033] Optionally, in step one, the heating temperature is 75-85°C, and the stirring time is 5-10min; in step two, the temperature of deionized water is 25-45°C, the stirring time after adding the chelating agent is 2-4min, and the heating temperature after adding the moisturizer and emulsifier stabilizer is 75-85°C, and the stirring time is 15-20min; in step three, the stirring speed during the stirring process of the oil phase mixture is 30-80r / min, and the stirring time is 3-5min, the speed during the homogenization process is 3000-4000r / min, and the homogenization time is 2-3min, and the temperature is maintained at 75-85°C after adding the aqueous phase mixture, and the homogenization time is continued for 2-4min; in step four, before adding the neutralizer, the homogenized mixture is cooled to 40-50°C, and the stirring time is 5-10min after adding the antibacterial agent and skin conditioner.
[0034] By adopting the above technical solution, various raw materials for preparing the cosmetic composition can fully react with each other, thereby obtaining a cosmetic composition with high efficiency in soothing sensitive skin.
[0035] In a third aspect, the present application provides an application of a cosmetic composition in lotions, emulsions, essences, ointments, and creams, using the following technical solution:
[0036] The invention discloses an application of a cosmetic composition in lotion, emulsion, essence, ointment and facial cream.
[0037] In summary, this application has the following beneficial effects:
[0038] 1. Since the present application adopts Inonotus birchii extract, peony root extract, saffron 360° soothing factor, kava extract, and oat kernel extract, the system formed by the mixture of these five ingredients can significantly improve the soothing effect of the cosmetic composition on sensitive skin, reduce the probability of erythema and red blood streaks on the skin, and form a protective barrier on the skin surface, thereby enhancing the stabilizing effect of the cosmetic composition.
[0039] 2. Since the present application adopts 5# sticky silicone oil, CETIOL CC, synthetic squalane and prickle fruit oil to prepare the emollient, it can promote the absorption of skin conditioning agents and moisturizing ingredients, and work together with skin conditioning to form a protective barrier on the skin surface, thereby improving the soothing effect of the cosmetic composition on the skin.
[0040] 3. Since the present application uses skin conditioners, emollients and moisturizers to work together, it promotes the skin's absorption of skin conditioners and improves the cosmetic composition to achieve a highly effective soothing effect. DETAILED DESCRIPTION
[0041] The present application is further described in detail below with reference to the embodiments.
[0042] Example
[0043] In this embodiment, the chelating agent is EDTA disodium; the thickening agent is a mixture of carbomer and CARBOPOL 940 in equal weights; and the emulsifying stabilizer is xanthan gum.
[0044] A cosmetic composition, wherein the components and amounts of the emulsifier, emollient, thickener, chelating agent, moisturizer, emulsion stabilizer, neutralizer, antibacterial agent, and skin conditioner used in Examples 1-4 are shown in Table 1, unit: g.
[0045] Table 1
[0046]
[0047]
[0048] Example 1
[0049] A cosmetic composition comprising the following raw materials by weight: 1 g of an emulsifier, 5 g of an emollient, 0.24 g of a thickener, 0.01 g of a chelating agent, 7 g of a moisturizer, 0.04 g of an emulsion stabilizer, 0.25 g of a neutralizer, 0.9 g of an antibacterial agent, 2.2 g of a skin conditioner, and 75 g of deionized water;
[0050] A cosmetic composition is prepared by the following method:
[0051] Step 1, mixing an emulsifier and an emollient, heating at 75° C., and stirring for 10 minutes to obtain an oil phase mixture;
[0052] Step 2: Mix the thickener with deionized water at a temperature of 25°C, add the chelating agent, stir for 4 minutes, then add the moisturizer and the emulsion stabilizer, heat at 75°C, stir for 20 minutes, and obtain an aqueous phase mixture;
[0053] Step 3, stirring the oil phase mixture obtained in step 1 at 30 r / min for 5 min, homogenizing at 3000 r / min for 3 min, adding the water phase mixture, maintaining the temperature at 75° C., and continuing homogenizing for 4 min to obtain a homogenous emulsified mixture;
[0054] Step 4: Cool the homogeneous emulsified mixture to 40° C., add a neutralizer, and then add an antibacterial agent and a skin conditioner, stir for 10 minutes, and cool to obtain a cosmetic composition.
[0055] Example 2
[0056] A cosmetic composition comprising the following raw materials by weight:
[0057] 1.4 g emulsifier, 6.5 g emollient, 0.28 g thickener, 0.03 g chelating agent, 9 g moisturizer, 0.06 g emulsion stabilizer, 0.29 g neutralizer, 1.3 g antibacterial agent, 2.4 g skin conditioner, 85 g deionized water.
[0058] A cosmetic composition is prepared by the following method:
[0059] Step 1, mixing an emulsifier and an emollient, heating at 85° C., and stirring for 5 minutes to obtain an oil phase mixture;
[0060] Step 2: Mix the thickener with deionized water at a temperature of 45°C, add the chelating agent, stir for 2 minutes, then add the moisturizer and the emulsion stabilizer, heat at 85°C, stir for 15 minutes, and obtain an aqueous phase mixture;
[0061] Step 3, stirring the oil phase mixture obtained in step 1 at 80 r / min for 3 min, homogenizing at 4000 r / min for 2 min, adding the water phase mixture, maintaining the temperature at 85° C., and continuing homogenizing for 2 min to obtain a homogenous emulsified mixture;
[0062] Step 4: Cool the homogenized emulsified mixture to 50° C., add a neutralizer, and then add an antibacterial agent and a skin conditioner, stir for 5 minutes, and cool to obtain a cosmetic composition.
[0063] Example 3
[0064] A cosmetic composition comprising the following raw materials by weight:
[0065] 1.2g emulsifier, 5.6g emollient, 0.26g thickener, 0.05g chelating agent, 8g moisturizer, 0.05g emulsion stabilizer, 0.27g neutralizer, 1.1g antibacterial agent, 2.3g skin conditioner, 80g deionized water;
[0066] A cosmetic composition is prepared by the following method:
[0067] Step 1, mixing an emulsifier and an emollient, heating at 80° C., and stirring for 7 minutes to obtain an oil phase mixture;
[0068] Step 2: Mix the thickener with deionized water at a temperature of 35° C., add the chelating agent, stir for 3 minutes, then add the moisturizer and the emulsion stabilizer, heat at 80° C., stir for 17 minutes, and obtain an aqueous phase mixture;
[0069] Step 3, stirring the oil phase mixture obtained in step 1 at 55 r / min for 4 min, homogenizing at 3500 r / min for 2.5 min, adding the water phase mixture, maintaining the temperature at 80° C., and continuing homogenizing for 3 min to obtain a homogenous emulsified mixture;
[0070] Step 4: Cool the homogenized emulsified mixture to 45° C., add a neutralizer, and then add an antibacterial agent and a skin conditioner, stir for 7 minutes, and cool to obtain a cosmetic composition.
[0071] Example 4
[0072] A cosmetic composition comprising the following raw materials by weight:
[0073] 1.1 g emulsifier, 6 g emollient, 0.25 g thickener, 0.02 g chelating agent, 7.8 g moisturizer, 0.05 g emulsion stabilizer, 0.28 g neutralizer, 1.2 g antibacterial agent, 2.3 g skin conditioner, 82 g deionized water;
[0074] A cosmetic composition is prepared by the following method:
[0075] Step 1, mixing an emulsifier and an emollient, heating at 75° C., and stirring for 8 minutes to obtain an oil phase mixture;
[0076] Step 2: Mix the thickener with deionized water at 40°C, add the chelating agent, stir for 3 minutes, then add the moisturizer and emulsion stabilizer, heat at 85°C, stir for 20 minutes, and obtain an aqueous phase mixture;
[0077] Step 3, stirring the oil phase mixture obtained in step 1 at 60 r / min for 3 min, homogenizing at 3000 r / min for 2 min, adding the water phase mixture, maintaining the temperature at 82° C., and continuing homogenizing for 2 min to obtain a homogenous emulsified mixture;
[0078] Step 4: Cool the homogenized emulsified mixture to 43° C., add a neutralizer, and then add an antibacterial agent and a skin conditioner, stir for 9 minutes, and cool to obtain a cosmetic composition.
[0079] Embodiment 5-7
[0080] A cosmetic composition, which is different from Example 3 in that the ingredients and amounts of the skin conditioners used in Examples 5-7 are as shown in Table 2, unit: g.
[0081] Table 2
[0082]
[0083] Examples 8-12
[0084] A cosmetic composition, which is different from Example 3 in that the weight ratios of the skin conditioner, emollient and moisturizer used in Examples 8-12 are as shown in Table 3.
[0085] Table 3
[0086]
[0087]
[0088] Comparative Example
[0089] Comparative Example 1
[0090] A cosmetic composition, which is different from Example 3 in that no Inonotus obliquus extract is used during the preparation process.
[0091] Comparative Example 2
[0092] A cosmetic composition, which is different from Example 3 in that oat kernel extract is not used in the preparation process.
[0093] Comparative Example 3
[0094] A cosmetic composition, which is different from Example 3 in that saffron 360° soothing factor is not used during the preparation process.
[0095] Comparative Example 4
[0096] A cosmetic composition, which is different from Example 3 in that no peony root extract is used in the preparation process.
[0097] Comparative Example 5
[0098] A cosmetic composition, which is different from Example 3 in that kava extract is not used during the preparation process.
[0099] Detection Methods
[0100] 1. Evaluation of anti-allergic efficacy
[0101] The emulsions containing the cosmetic compositions of Examples 1-12 and Comparative Examples 1-5 were subjected to an anti-allergic test. The test method used the Elson-Morgan method, and the specific steps were as follows: 0.1 mL of 2.5 mmol / L CaCl2 was added to 0.5 mL of hyaluronidase (600 U / mL), and the mixture was kept at 37°C for 20 min; 0.5 mL of the emulsion was added, and the mixture was kept at 37°C for 20 min; 2 mL of 0.4 mg / mL sodium hyaluronate was added, and the mixture was kept at 37°C for 40 min; 1 mL of acetylacetone solution was added, and the mixture was heated in a boiling water bath for 15 min, and immediately cooled with ice water for 5 min; finally, 1.0 mL of Ehrlich reagent was added, and the mixture was placed at room temperature for 60 min to develop color, and the absorbance was measured at 530 nm. The calculation formula for the inhibition rate of the sample on hyaluronidase is:
[0102] Hyaluronidase inhibition rate (%) = [(AB) - (CD)] / (AB) × 100%
[0103] Wherein A represents: the absorbance of the control solution (using acetate buffer instead of sample solution), B represents: the absorbance of the control blank solution (using acetate buffer instead of sample solution and enzyme solution), C represents: the absorbance of the sample solution, and D represents: the absorbance of the sample blank solution (using acetate buffer instead of enzyme solution).
[0104] The number of parallel samples for each group of samples was five, and the average hyaluronidase inhibition rate of each group was calculated and recorded in Table 4.
[0105] 2. Test for Transdermal Water Loss (TEWL)
[0106] The emulsions comprising the cosmetic compositions of Examples 1-12 and Comparative Examples 1-5 were tested for skin water loss (TEWL), and the testing method was as follows: 510 subjects aged between 21 and 42 were invited, and the subjects were randomly divided into 17 groups, each with 30 people. Each group used the same test sample, and the first group of subjects used the emulsion comprising the cosmetic composition of Example 1, the second group of subjects used the emulsion comprising the cosmetic composition of Example 2, and so on. The subjects applied the emulsion to the entire face at a dosage of 0.50±0.05g, once in the morning and once in the evening every day, for 4 consecutive weeks. They were required to sit quietly and relax in the test environment before each collection, and the TEWL value was tested with a Vapometer transepidermal water loss meter at 30 minutes; the △TEWL calculation formula is:
[0107] △TEWL=(TEWL1-TEWL2) / TEWL1×100%
[0108] In the formula, TEWL1: the value before using the product; TEWL2: the value after using the product for 4 weeks;
[0109] The larger the △TEWL, the greater the reduction in transepidermal water loss, and the better the repair effect. The average △TEWL value of each group was calculated and recorded in Table 4.
[0110] 3. Capsaicin stimulation test
[0111] The emulsions containing the cosmetic compositions of Examples 1-12 and Comparative Examples 1-5 were subjected to a capsaicin irritation test, and the test method was as follows: 170 subjects aged 21 to 42 were invited, and the subjects were randomly divided into 17 groups, 10 in each group, and each group used the same test sample. The first group of subjects used an emulsion containing the cosmetic composition of Example 1, and the second group of subjects used an emulsion containing the cosmetic composition of Example 2, and so on. The test area was the nasolabial groove on the right side of the volunteer. A 0.01% capsaicin solution was applied to the nasolabial groove on the right side of the volunteer. When the tingling sensation reached moderate or above, the emulsion was applied to the test area. By observing the redness of the test site and evaluating the change in the degree of tingling, the tingling score of the test area 60 minutes after applying the emulsion was recorded. The score range was 0-3 points, 0 for no feeling, 1 for mild tingling, 2 for moderate tingling, and 3 for severe tingling. The average tingling value of each group was calculated and recorded in Table 4.
[0112] 4. Anti-inflammatory effect and red blood removal effect test
[0113] The emulsions containing the cosmetic compositions of Examples 1-12 and Comparative Examples 1-5 were tested for the scores of the red area on the face; the testing method was as follows: 170 women with sensitive skin (accumulated tingling sensation ≥ 3 points), aged 25-40 years old, were selected. They were randomly divided into 17 groups, each with 10 people. Each group used the same test sample. The first group of subjects used the emulsion containing the cosmetic composition of Example 1, the second group of subjects used the emulsion containing the cosmetic composition of Example 2, and so on. According to the requirements, the subjects were required to use the product continuously, applying it twice a day in the morning and evening, for 28 consecutive days, and a return visit was required on the 28th day of the test (D28). The test of the same subject was completed by the same measurement personnel. No product can be used on the test area for the first 15 days. After thoroughly cleaning the face with a uniform cleansing product, gently wipe it dry with a paper towel, wait for 15 minutes in a room with a room temperature of 22°C ± 2°C and a relative humidity of 40 ± 2%, then take a facial photo of the test subject with a VISIA facial image analyzer, perform statistical analysis on the absolute scores obtained, record the detection data of the red area of the subject's face, calculate the average red area value of each group and record it in Table 4.
[0114] Table 4
[0115]
[0116] In combination with Examples 1-7 and Table 4, it can be seen that the addition of allantoin and Deminshu can significantly improve the hyaluronidase inhibition rate, △TEWL, and red zone value of the cosmetic composition, and reduce the skin tingling sensation; this is because allantoin can enhance the skin's immunity and improve the barrier function of the skin's natural acid film, and Deminshu contains natural oat derivatives, which can reduce free radical-induced skin damage and have a calming and soothing effect on the skin. The two work together to enhance the skin's immunity while improving the skin's natural barrier function, so that the cosmetic composition can achieve the effect of both repairing and strengthening, and then work together with other ingredients in the skin conditioner to promote the skin to form a healthy state of positive circulation, and improve the soothing and stabilizing effects of the cosmetic composition on the skin.
[0117] In combination with Examples 3, 8-12 and Table 4, it can be seen that when the dosage ratio of skin conditioners, emollients and moisturizers is appropriate, the hyaluronidase inhibition rate, △TEWL, and red zone value of the cosmetic composition can be improved, and the skin stinging sensation can be reduced, that is, by improving the anti-allergic effect and barrier protection effect of the cosmetic skin, thereby improving the soothing effect of the cosmetic composition on the skin. When the dosage ratio of skin conditioners, emollients and moisturizers is too small or too large, the hyaluronidase inhibition rate, △TEWL, and red zone value of the cosmetic composition will be reduced, and the skin stinging sensation will be increased. This may be because the mixed system formed by skin conditioners, emollients and moisturizers can promote the skin's absorption of the effective ingredients in the cosmetic composition, thereby forming a positive cycle of skin health, so that the skin can be stabilized in a healthy state for a long time, reducing external environmental stimulation, thereby achieving the soothing effect and long-term stabilization effect of the cosmetic composition.
[0118] In combination with Examples 3, 1-5 and Table 4, it can be seen that when any one of the components in the skin conditioner formed by Inonotus birchii extract, peony root extract, saffron 360° soothing factor, kava extract, and oat kernel extract is missing, the hyaluronidase inhibition rate, △TEWL, and red zone value of the cosmetic composition will be reduced, and the skin stinging sensation will be increased.
[0119] This specific embodiment is merely an explanation of the present application and is not a limitation of the present application. After reading this specification, those skilled in the art may make modifications to the present embodiment without any creative contribution as needed, but such modifications are protected by the patent law as long as they are within the scope of the claims of the present application.
Claims
1. A cosmetic composition, characterized in that: The invention comprises the following raw materials in parts by weight: 1-1.4 parts of emulsifier, 5-6.5 parts of emollient, 0.24-0.28 parts of thickener, 0.01-0.03 parts of chelating agent, 7-9 parts of moisturizing agent, 0.04-0.06 parts of emulsion stabilizer, 0.25-0.29 parts of neutralizing agent, 0.9-1.3 parts of antibacterial agent, 2.2-2.4 parts of skin conditioning agent, and 75-85 parts of deionized water; Taking the skin conditioner as a reference, the skin conditioner comprises the following raw materials in parts by weight: 0.0008-0.0012 parts of inonotus birchii extract, 1.2-1.8 parts of peony root extract, 0.15-0.25 parts of saffron 360° soothing factor, 0.15-0.25 parts of kava extract, and 0.15-0.25 parts of oat kernel extract; The weight ratio of the skin conditioner, emollient, and moisturizer is 1:(2.4-2.6):(3.4-3.6); Based on the emollient, the emollient includes 1.2-1.8 parts of 5# sticky silicone oil, 1.6-2.4 parts of CETIOL CC, 1.6-2.4 parts of synthetic squalane, and 0.1-0.12 parts of prickle fruit oil; Based on the moisturizer, the moisturizer includes 4.5-5.5 parts of glycerin, 0.008-0.012 parts of HA macromolecules, and 2.5-3.5 parts of DPG; Taking the emulsifier as a benchmark, the emulsifier is compounded by MONTANOV 68 MB and Top-care GMS165 in a weight ratio of 1: (0.8-1.2).
2. A cosmetic composition according to claim 1, characterized in that: Based on the skin conditioner, the skin conditioner also includes 0.15-0.25 parts of allantoin and 0.15-0.25 parts of Deminshu.
3. A cosmetic composition according to claim 1, characterized in that: Taking the antibacterial agent as a benchmark, the antibacterial agent is compounded by cinnamaldehyde and hexanediol in a weight ratio of 1: (0.8-1.2).
4. A cosmetic composition according to claim 1, characterized in that: The neutralizing agent is arginine.
5. The method for preparing the cosmetic composition according to any one of claims 1 to 4, characterized in that: The following steps are involved: Step 1, mixing an emulsifier and an emollient, heating, and stirring to obtain an oil phase mixture; Step 2, mixing the thickener with deionized water, adding the chelating agent, stirring, and then adding the moisturizer and the emulsion stabilizer, heating, and stirring to obtain an aqueous phase mixture; Step 3, stirring and homogenizing the oil phase mixture obtained in step 1, adding the water phase mixture, heating, and continuing to homogenize to obtain a homogenous emulsified mixture; Step 4: Cool the homogenized emulsified mixture, add a neutralizer, then add an antibacterial agent and a skin conditioner, stir, and cool to obtain a cosmetic composition.
6. Use of the cosmetic composition according to any one of claims 1 to 4 in the preparation of lotions, emulsions, essences, ointments and creams.
Citation Information
Patent Citations
Soothing and repairing composition and application thereof
CN114099409A
Cosmetic composition with immediate soothing effect, cosmetic and preparation method of cosmetic composition
CN115350130A