Nursing eyewash capable of relieving eye fatigue and preparation method thereof

Abstract

The invention discloses a nursing eyewash liquid capable of relieving eye fatigue and a preparation method thereof. 6 The product comprises the following raw materials by weight: 2 to 30 parts of vitamins, 30 to 100 parts of taurine, 9000 to 9500 parts of sodium salt, 10 to 60 parts of zinc gluconate, 4.5 to 6 parts of borneol, 0.005 to 0.01 parts of Chinese medicine extract, 0.001 to 0.003 parts of growth factor, 0.01 to 0.03 parts of pearl powder and pH regulator, and the balance is water; the pH value of the nursing eyewash liquid that can relieve eye fatigue is 6.2 to 7.8. The nursing eyewash liquid that can relieve eye fatigue disclosed by the present invention has good sterilization biological activity, has less irritation to the eyes, and the Chinese medicine extract and other natural materials used have no side effects, can enhance the moisture of the eyes, effectively relieve eye fatigue and prevent the occurrence of dry eyes.

Description

Technical Field

[0001] The invention belongs to the technical field of eyewash preparations, and in particular relates to a nursing eyewash capable of relieving eye fatigue and a preparation method thereof. Background Art

[0002] Eyewash is a popular product with a much wider range of applications than general equipment and medicines. Eyewash is added with pure natural active substances, and is mixed with purified water or distilled water and inorganic salts to form a solution suitable for the human body. It cleans and maintains the eyes, relieves eye fatigue, maintains eye cleanliness, alleviates some eye diseases, and repairs some minor physical damage in the eyes. It can also stimulate the microvascular circulation of the eyes, meet the nutrient needs of the eye skin, and improve the dark circles caused by fatigue, staying up late and poor sleep. It is deeply loved by consumers.

[0003] The main ingredients of eyewashes currently on the market include ampheniramine maleate, sodium chondroitin sulfate, dipotassium glycyrrhizinate, vitamin B6, taurine, vitamin B12, etc. Among them, dipotassium glycyrrhizinate, ampheniramine maleate and other ingredients have anti-inflammatory and antihistamine effects, but long-term use may lead to dysbiosis of the ocular surface flora. In addition, in order to extend the shelf life, preservatives are often added to eyewashes. Preservatives can destroy the mucin on the surface of the cornea, damage the cornea, and in severe cases can cause blindness. Long-term and frequent use of eyewashes can easily increase the risk of ocular surface diseases.

[0004] Therefore, there is an urgent need for a nutrient eye wash that can relieve eye fatigue, relieve eye itching, and keep both eyes moist. Summary of the invention

[0005] The purpose of the present invention is to provide a nursing eyewash liquid capable of relieving eye fatigue and a preparation method thereof, which can solve the problems of the eyewash liquid in the background technology.

[0006] To achieve the above purpose, the present invention provides a nursing eyewash liquid that can relieve eye fatigue, with 1*10 6 The product comprises the following raw materials in parts by weight: 2 to 30 parts of vitamins, 30 to 100 parts of taurine, 9000 to 9500 parts of sodium salt, 10 to 60 parts of zinc gluconate, 4.5 to 6 parts of borneol, 0.005 to 0.01 parts of Chinese medicine extract, 0.001 to 0.003 parts of growth factor, 0.01 to 0.03 parts of pearl powder and pH regulator, and the balance is water;

[0007] The pH value of eye wash solution that can relieve eye fatigue is 6.2 to 7.8.

[0008] Furthermore, with 1*10 6The product comprises the following raw materials in parts by weight: 15-25 parts of vitamins, 45-60 parts of taurine, 9000-9010 parts of sodium salt, 15-30 parts of zinc gluconate, 4.5-5.0 parts of borneol, 0.005-0.008 parts of traditional Chinese medicine extract, 0.002-0.003 parts of growth factor, 0.01-0.02 parts of pearl powder, and the balance is water. The pH value of the nursing eyewash for relieving eye fatigue is 6.5-7.5.

[0009] Furthermore, with 1*10 6 The product includes the following raw materials in parts by weight: 21 parts of vitamins, 50 parts of taurine, 9000 parts of sodium salt, 20 parts of zinc gluconate, 4.5 parts of borneol, 0.005 parts of traditional Chinese medicine extract, 0.002 parts of growth factor, 0.01 parts of pearl powder, and the balance is water. The pH value of the nursing eyewash that can relieve eye fatigue is 7.2.

[0010] Furthermore, the vitamins include vitamin B12, vitamin B6 and vitamin A in a mass ratio of 1 to 3:10:10 to 20.

[0011] In the present invention, vitamin B12 can protect the optic nerve, eliminate fatigue, avoid congestion, and prevent eye diseases. It also has a good alleviating effect on dry eyes, astringent eyes, itchy eyes, swollen eyes, and other problems, and can achieve the effect of protecting and nourishing the eyes; vitamin B6 can promote metabolism, promote eye nutrition, avoid conjunctival congestion, maintain the health of the eye nervous system, and have an antioxidant effect; vitamin A can moisturize the eyes, protect the lacrimal glands, keep the inside of the eyes moist, and maintain the normal function of the lacrimal glands, so that the tears in the eyes can be effectively supplemented, and the symptoms of dryness and itching in the eyes due to insufficient tear secretion can be prevented. The three are used together, and on the basis of preventing dry and itchy eyes, the eyes can be moisturized, the eyes can be kept bright and clear, and the cornea can be protected.

[0012] Furthermore, the Chinese medicine extract includes blue chamomile extract, coptis chinensis extract, honeysuckle extract and atractylodes extract in a mass ratio of 1 to 2:1 to 2:2:2.

[0013] In the present invention, the blue chamomile extract (which may also be a commercially available hydrosol) can relieve eye fatigue, repair damaged corneal cells, and improve the anti-allergic and hypoallergenic properties; the coptis extract contains rich berberine hydrochloride, which can improve the anti-inflammatory effect of the eyes, clear away heat and promote blood circulation in the eyes; coptis is used together with honeysuckle and atractylodes to effectively regulate the tear function, and has obvious antibacterial and bactericidal effects, which can keep the inside of the eyes clean and moisturized.

[0014] Further, the growth factors include fibroblast growth factor and epidermal growth factor.

[0015] In the present invention, the addition of growth factors can accelerate the rate of cell mitosis and promote cell proliferation, which is used to repair corneal and conjunctival epithelial cells. After inhibiting and killing bacteria, it plays a role in protecting cells around the eyes and avoiding eye irritation.

[0016] Furthermore, the pH adjuster is hydrochloric acid and / or sodium hydroxide with a concentration of 0.5 to 1.0 mol / L.

[0017] In the present invention, the pH value of the nursing eyewash solution that can relieve eye fatigue should be close to the pH value of tears. Therefore, during the preparation process, due to the different contents of raw materials, the pH value of the solution after specific preparation should be adjusted. Therefore, hydrochloric acid or sodium hydroxide is used for acid-base adjustment in the present invention to make the pH value of the nursing eyewash solution that can relieve eye fatigue 6.2-7.8, which is gentle and non-irritating when washing eyes.

[0018] Further, the sodium salt includes sodium hyaluronate and / or sodium chloride.

[0019] In the present invention, the sodium hyaluronate solution has the effect of replenishing water and moisturizing the eyeball, and can also treat corneal epithelial damage, and can promote the connection and extension of corneal epithelial cells, promote corneal wound healing and retain water. The sodium chloride solution can lubricate the cornea and conjunctiva, and relieve dry eyes and fatigue. The combination of the two can reduce the irritation of the drug, promote metabolism on the basis of maintaining the moisture of the eye tissue, so that the eyes can reach a comfortable state.

[0020] Furthermore, the present invention also discloses a method for preparing the above-mentioned nursing eyewash liquid capable of relieving eye fatigue, comprising the following steps:

[0021] (1) Extraction of Chinese herbal medicine extract

[0022] Weigh atractylodes, coptis root, honeysuckle and blue chamomile, mix and grind, sieve to obtain Chinese medicine powder, add distilled water and boil repeatedly, filter the boiled solution to obtain Chinese medicine extract;

[0023] (2) Preparation of solution

[0024] According to the weight of the raw materials, add sodium salt to 500 parts of purified water under stirring, continue stirring for 15 to 30 minutes, and then add the other raw materials except the pH adjuster one by one under stirring, and each raw material needs to be added after the previous raw material is dissolved;

[0025] Use pH regulator to adjust the solution pH to 6.2-7.8, add water to 1*10 6 share;

[0026] (3) Assembly

[0027] The solution obtained in step (2) can be obtained after filtering, sterilizing and replacing.

[0028] Furthermore, in step (2), the water temperature during the dissolution of the raw materials is 10-30° C., and the stirring and dissolving time of each raw material is not less than 30 min.

[0029] Furthermore, filtration sterilization is performed using a 2nd-grade 0.2 μm polyethersulfone microporous filter element.

[0030] In summary, the present invention has the following advantages:

[0031] 1. The nursing eyewash liquid for relieving eye fatigue prepared by the present invention first regulates eye cells through sodium salt, moisturizes the cornea and conjunctiva, and relieves dry eyes; then promotes metabolism through vitamins, improves eye function, further moisturizes the eyes, and protects the cornea; further, the tear function can be regulated by the Chinese medicine extract, so that it can continuously enhance the stability of the tear film and enhance the moistness of the eyes. At the same time, the 18 kinds of amino acids such as leucine, methionine, and alanine contained in the pearl powder after hydrolysis can improve symptoms such as eye swelling, eye itching, eye pain, dry eyes, and eye astringency; further, the growth factor begins to accelerate cell mitosis in a well-moistened eye environment, repairs corneal and conjunctival epithelial cells, and avoids the stimulation caused by excess sodium hyaluronate solution. Under the action of the growth factor, zinc gluconate can provide zinc, which participates in the conduction and metabolism of multiple structures in the retina and the eye with the synthesis of multiple enzymes and proteins in the body, thereby better improving eye function and promoting eye tissue metabolism, and preventing and treating the occurrence of various eye diseases.

[0032] 2. The nursing eyewash solution for relieving eye fatigue prepared by the present invention has good sterilization biological activity, can relieve dry eyes symptoms and eye fatigue without destroying the lipid layer, aqueous layer and mucin layer on the surface of the eye.

[0033] 3. The eye wash liquid for relieving eye fatigue prepared by the present invention is a mild eye wash liquid with minimal irritation to the eyes and no side effects. It can activate eye cells, improve microvascular circulation, discharge toxins, eliminate eye fatigue, dry eyes, improve myopia, blurred vision, and make eyes bright. DETAILED DESCRIPTION

[0034] The principles and features of the present invention are described below in conjunction with the examples, which are only used to explain the present invention and are not intended to limit the scope of the present invention. If no specific conditions are specified in the examples, the conditions are carried out according to conventional conditions or the conditions recommended by the manufacturer. If the manufacturer of the reagents or instruments is not specified, they are all conventional products that can be purchased commercially.

[0035] Example 1

[0036] This embodiment provides an eye wash solution for care that can relieve eye fatigue, comprising the following components:

[0037] Vitamin 21g, taurine 50g, sodium salt 9005g, zinc gluconate 20g, borneol 4.5g, Chinese medicine extract 0.005g, growth factor 0.002g, pearl powder 0.01g, mix and dissolve all materials with purified water and make the volume to 1000L.

[0038] The pH value of the eye wash solution for relieving eye fatigue is adjusted to 7.2 with 1 mol / L NaOH solution.

[0039] In this embodiment, the vitamins include 10 g of vitamin B12, 10 g of vitamin B6 and 1 g of vitamin A. The sodium salt includes 9000 g of sodium chloride and 5 g of sodium hyaluronate. The Chinese medicine extract includes 0.001 g of blue chamomile extract, 0.001 g of coptis extract, 0.002 g of honeysuckle extract and 0.001 g of atractylodes extract. The growth factor includes 0.001 g of fibroblast growth factor and 0.001 g of epidermal growth factor.

[0040] This embodiment also provides a method for preparing the above-mentioned nursing eyewash liquid that can relieve eye fatigue, comprising the following steps:

[0041] (1) Extraction of Chinese herbal medicine extract

[0042] Weigh atractylodes, coptis root, honeysuckle and blue chamomile, crush and sieve to obtain a Chinese medicine powder, add distilled water and repeatedly decoct for 5 times, mix the solutions after 5 decoctions, and then filter to obtain a Chinese medicine extract (if necessary, further impurities can be removed or alcohol extraction can be performed);

[0043] (2) Dissolve sodium hyaluronate

[0044] Take a 1000mL glass beaker, add 500mL purified water, heat to 60°C, and add a magnetic stirrer; weigh another 5g of sodium hyaluronate, add an appropriate amount of purified water to moisten it, and add it to the above beaker, stir at 450rpm for 2h until the sodium hyaluronate is completely dissolved, and set aside.

[0045] (3) Preparation of solution

[0046] Add about 800L of purified water at a temperature of 15°C to the liquid preparation tank, add the sodium hyaluronate solution of step (2) under stirring, continue stirring for 30 minutes, and then add the other raw materials except the sodium hydroxide solution. Each raw material needs to be added after the previous raw material is dissolved;

[0047] After all the raw materials except the sodium hydroxide solution are dissolved, stir for another 30 minutes, then add the sodium hydroxide solution to adjust the pH of the solution to 7.2, and add water to make the volume to 1000L;

[0048] (3) Assembly

[0049] The solution obtained in step (2) is filtered, sterilized and replaced by a second-level 0.2 μm polyethersulfone microporous filter element to obtain the product.

[0050] Example 2

[0051] This embodiment provides an eye wash solution for care that can relieve eye fatigue, comprising the following components:

[0052] Vitamin 25g, taurine 30g, sodium salt 9005g, zinc gluconate 10g, borneol 6g, Chinese medicine extract 0.009g, growth factor 0.002g, pearl powder 0.03g, mix and dissolve all materials in purified water and adjust the volume to 1000L.

[0053] The pH value of the eye wash solution for relieving eye fatigue is adjusted to 7.0 with 1 mol / L NaOH solution.

[0054] In this embodiment, the vitamins include 10g of vitamin B12, 12g of vitamin B6 and 3g of vitamin A. The sodium salt includes 9000g of sodium chloride and 5g of sodium hyaluronate. The Chinese medicine extract includes 0.0015g of blue chamomile extract, 0.0015g of coptis extract, 0.003g of honeysuckle extract and 0.003g of atractylodes extract. The growth factor includes 0.001g of fibroblast growth factor and 0.001g of epidermal growth factor.

[0055] This embodiment also provides a method for preparing the above-mentioned nursing eyewash liquid that can relieve eye fatigue, comprising the following steps:

[0056] (1) Extraction of Chinese herbal medicine extract

[0057] Weigh atractylodes, coptis root, honeysuckle and blue chamomile, crush and sieve to obtain a Chinese medicine powder, add distilled water and repeatedly decoct for 4 times, mix the solutions after 4 decoctions, and then filter to obtain a Chinese medicine extract (if necessary, further impurities can be removed or alcohol extraction can be performed);

[0058] (2) Dissolve sodium hyaluronate

[0059] Take a 1000mL glass beaker, add 500mL purified water, heat to 50°C, and add a magnetic stirrer; weigh another 5g of sodium hyaluronate, add an appropriate amount of purified water to moisten it, and add it to the above beaker, stir at 450rpm for 2h until the sodium hyaluronate is completely dissolved, and set aside.

[0060] (3) Preparation of solution

[0061] Add about 800L of purified water at a temperature of 20°C to the liquid preparation tank, add the sodium hyaluronate solution of step (2) under stirring, continue stirring for 30 minutes, and then add the other raw materials except the sodium hydroxide solution. Each raw material needs to be added after the previous raw material is dissolved;

[0062] After all the raw materials except the sodium hydroxide solution are dissolved, stir for another 30 minutes, then add the sodium hydroxide solution to adjust the pH of the solution to 7.0, and add water to make the volume to 1000L;

[0063] (3) Assembly

[0064] The solution obtained in step (2) is filtered, sterilized and replaced by a second-level 0.2 μm polyethersulfone microporous filter element to obtain the product.

[0065] Example 3

[0066] This embodiment provides an eye wash solution for care that can relieve eye fatigue, comprising the following components:

[0067] Vitamin 30g, taurine 100g, sodium salt 9005g, zinc gluconate 60g, borneol 4.5g, Chinese medicine extract 0.005g, growth factor 0.002g, pearl powder 0.03g, mix and dissolve all materials with purified water, and adjust the volume to 1000L.

[0068] The pH value of the eye wash solution for relieving eye fatigue is adjusted to 6.2 with 1 mol / L NaOH solution.

[0069] In this embodiment, the vitamins include 10 g of vitamin B12, 17 g of vitamin B6 and 3 g of vitamin A. The sodium salt includes 9000 g of sodium chloride and 5 g of sodium hyaluronate. The Chinese medicine extract includes 0.001 g of blue chamomile extract, 0.001 g of coptis extract, 0.002 g of honeysuckle extract and 0.001 g of atractylodes extract. The growth factors include 0.001 g of fibroblast growth factor and 0.001 g of epidermal growth factor.

[0070] This embodiment also provides a method for preparing the above-mentioned nursing eyewash liquid that can relieve eye fatigue, comprising the following steps:

[0071] (1) Extraction of Chinese herbal medicine extract

[0072] Weigh atractylodes, coptis root, honeysuckle and blue chamomile, crush and sieve to obtain a Chinese medicine powder, add distilled water and repeatedly decoct for 3 times, mix the solutions after 3 decoctions, and then filter to obtain a Chinese medicine extract (if necessary, further impurities can be removed or alcohol extraction can be performed);

[0073] (2) Dissolve sodium hyaluronate

[0074] Take a 1000mL glass beaker, add 500mL purified water, heat to 55°C, and add a magnetic stirrer; weigh another 5g of sodium hyaluronate, add an appropriate amount of purified water to moisten it, and add it to the above beaker, stir at 450rpm for 2h until the sodium hyaluronate is completely dissolved, and set aside.

[0075] (3) Preparation of solution

[0076] Add about 800L of purified water at a temperature of 30°C to the liquid preparation tank, add the sodium hyaluronate solution of step (2) under stirring, continue stirring for 30 minutes, and then add the other raw materials except the sodium hydroxide solution. Each raw material needs to be added after the previous raw material is dissolved;

[0077] After all the raw materials except the sodium hydroxide solution are dissolved, stir for another 30 minutes, then add sodium hydroxide solution to adjust the solution pH to 7.5, and add water to make the volume to 1000L;

[0078] (3) Assembly

[0079] The solution obtained in step (2) is filtered, sterilized and replaced by a second-level 0.2 μm polyethersulfone microporous filter element to obtain the product.

[0080] Comparative Example 1

[0081] The difference between this comparative example and Example 1 is that the vitamin is 21 g of vitamin B12, and vitamin B6 and vitamin A are not included.

[0082] Comparative Example 2

[0083] The difference between this comparative example and Example 1 is that the vitamin is 21 g of vitamin A, and vitamin B6 and vitamin B12 are not included.

[0084] Comparative Example 3

[0085] This comparative example differs from Example 1 in that it does not contain vitamins.

[0086] Comparative Example 4

[0087] The difference between this comparative example and Example 1 is that the Chinese medicine extracts include 0.001 g of blue chamomile extract, 0.002 g of coptis chinensis extract and 0.002 g of honeysuckle extract, but do not include atractylodes lancea extract.

[0088] Comparative Example 5

[0089] The difference between this comparative example and Example 1 is that the Chinese medicine extract is 0.001g of blue chamomile extract, 0.002g of coptis chinensis extract and 0.002g of atractylodes lancea extract, but does not include honeysuckle extract.

[0090] Comparative Example 6

[0091] The difference between this comparative example and Example 1 is that no blue chamomile extract is added.

[0092] Comparative Example 7

[0093] The difference between this comparative example and Example 1 is that no Chinese medicine extract is added.

[0094] Comparative Example 8

[0095] The difference between this comparative example and Example 1 is that no growth factor is added.

[0096] Comparative Example 9

[0097] The difference between this comparative example and Example 1 is that zinc gluconate and pearl powder are not added.

[0098] Test Example 1

[0099] The preparations of comparative examples 1-9 were compared with the nursing eyewash for relieving eye fatigue prepared in Example 1 and the commercially available Zhenshiming little yellow duck eyewash. A comparative experiment was conducted. 110 office workers who used computers excessively at work were selected and randomly divided into 11 groups, with 10 people in each group. The preparations of comparative examples 1-9, the nursing eyewash for relieving eye fatigue prepared in Example 1 and the commercially available Zhenshiming little yellow duck eyewash were used respectively for washing three times a day, and the relief conditions after washing were compared, as shown in Table 1.

[0100] Table 1 Short-term relief

[0101]

[0102] As can be seen from Table 1, the nursing eyewash liquid that can relieve eye fatigue in the present invention is composed of a variety of functional components, each of which has a certain impact on the final effect of the eyewash liquid. Only when all the components in the present invention are present can the best effect of relieving fatigue and relieving dryness be achieved. In the present invention, vitamins can protect the optic nerve, eliminate fatigue, and relieve symptoms such as dry eyes and astringent eyes; Chinese medicine extracts can keep the inside of the eyes clean and improve the ability of the eyes to moisturize and retain moisture; growth factors can quickly repair corneal and conjunctival epithelial cells to avoid eye irritation; pearl powder can further improve symptoms such as eye swelling, itchy eyes, eye pain, dry eyes, and astringent eyes. The components work synergistically to relieve symptoms of dry eyes, relieve eye fatigue, and improve vision.

[0103] Test Example 2

[0104] 1. Patient screening

[0105] 100 customers of an eyewash store were selected, all of whom suffered from dry eye syndrome. They were divided into two groups using a random number table method, with 50 cases in each group. One group was the experimental group, with 32 males and 18 females, aged 33.5±7.9 years old, with a course of disease of more than one year but less than two years. The other group was the control group, with 40 males and 10 females, aged 34.6±8.2 years old, with a course of disease of more than one year but less than two years.

[0106] There was no significant difference in the general information of the two groups (P<0.05), indicating that the two groups were comparable.

[0107] The diagnosis refers to the diagnostic criteria of "white and astringent syndrome" in "Traditional Chinese Ophthalmology": ① Subjective symptoms such as dry eyes, foreign body sensation, fatigue, photophobia, and red eyes; ② Tear breakup time (BUT) ≤ 5s; ③ Tear secretion test (SIT) ≤ 5mm / 5min.

[0108] 2. Experimental methods

[0109] Control group: patients were given Zhenshiming Little Yellow Duck Eyewash, 2 times a day, 5-10 mL per eye each time. Continuous treatment for 4 weeks constituted a course of treatment.

[0110] Experimental group: patients were given the nursing eyewash solution for relieving eye fatigue prepared in Example 1, 2 times / day, 5-10 mL per eye each time. Continuous treatment for 4 weeks constituted a course of treatment.

[0111] 3. Efficacy standards

[0112] Observation indicators: ① clinical efficacy of the two groups; ② basal tear secretion (SIT) and tear breakup time (BUT) of the two groups before and after treatment.

[0113] standard:

[0114] Markedly effective: After treatment, the patient's clinical symptoms basically disappeared, BUT>10s and SIT>10mm / 5min;

[0115] Improvement: After treatment, the patient's clinical symptoms were alleviated, BUT was significantly prolonged, and SIT was significantly increased;

[0116] Ineffective: After treatment, the patient's clinical symptoms did not improve, and BUT and SIT did not improve significantly.

[0117] 4. Experimental results

[0118] Table 2 Comparison of efficacy between the two groups

[0119] Group Number of cases Significant effect Improvement invalid Total Effectiveness Experimental Group 50 15 27 8 84％ Control group 50 10 17 23 54％

[0120] Table 3 Comparison of BUT and SIT between the two groups before and after treatment

[0121]

[0122] It can be seen from Table 2 and Table 3 that the nursing eyewash liquid for relieving eye fatigue prepared by the present invention has high efficacy, and compared with commercially available products, it can more effectively relieve and prevent the occurrence of dry eyes and enhance the moisture content of the eyes.

[0123] Although the specific implementation of the present invention has been described in detail, it should not be understood as limiting the scope of protection of this patent. Within the scope described in the claims, various modifications and variations that can be made by those skilled in the art without creative work still fall within the scope of protection of this patent.

Claims

1. A nursing eyewash liquid that can relieve eye fatigue, characterized in that: Includes the following components: Vitamin 21g, taurine 50g, sodium salt 9005g, zinc gluconate 20g, borneol 4.5g, Chinese medicine extract 0.005g, growth factor 0.002g, pearl powder 0.01g, all materials are mixed and dissolved in purified water, and the volume is fixed to 1000L; The pH value of the eye wash solution for relieving eye fatigue is 7.2; The vitamins include 10g of vitamin B12, 10g of vitamin B6 and 1g of vitamin A; the sodium salt includes 9000g of sodium chloride and 5g of sodium hyaluronate; the Chinese medicine extract includes 0.001g of blue chamomile extract, 0.001g of coptis extract, 0.002g of honeysuckle extract and 0.001g of atractylodes extract; the growth factors include 0.001g of fibroblast growth factor and 0.001g of epidermal growth factor; The method for preparing the nursing eyewash liquid capable of relieving eye fatigue comprises the following steps: (1) Preparation of Chinese medicine extracts Weigh atractylodes, coptis root, honeysuckle and blue chamomile, crush and sieve them, mix them to obtain Chinese medicine powder, add distilled water and boil them repeatedly, and filter the boiled solution to obtain Chinese medicine extract; (2) Preparation of solution According to the weight of the raw materials, add sodium salt to 500 parts of purified water under stirring, continue stirring for 15 to 30 minutes, and then add the other raw materials except the pH adjuster one by one under stirring. Each raw material needs to be added after the previous raw material is dissolved; Use pH regulator to adjust the solution pH to 7.2, add water to 1*10 6 share; (3) Assembly The solution obtained in step (2) is filtered, sterilized and replaced to obtain the product.

2. The eyewash solution for relieving eye fatigue according to claim 1, characterized in that: The water temperature for dissolving the raw materials in step (2) of the preparation method is 10-30° C., and the stirring and dissolving time of each raw material is not less than 30 min.

3. The eyewash solution for relieving eye fatigue according to claim 1, characterized in that: The preparation method uses a second-level 0.2 μm polyethersulfone microporous filter element for filtration sterilization.

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