A lung nodule localization device and system

Abstract

The present application relates to the technical field of medical devices, in particular to a lung nodule positioning device and system. The lung nodule positioning device and system provided by the present application comprises a distal end, an intermediate connecting section and a proximal end, and the intermediate connecting section is connected with the distal end and the proximal end on both sides respectively; characterized in that the intermediate connecting section has an elastic contraction function, the distal end comprises an anchor hook and a blocking part for connecting the anchor hook and the intermediate connecting section, and the blocking part is adapted to the inner diameter of the delivery tube. The technical problem of large bleeding caused by the small radial area of the mechanism formed by bending a single spring wire in the prior art is solved.

Description

Technical Field

[0001] This invention relates to the technical field of medical devices, and in particular to a lung nodule localization device and system. Background Technology

[0002] Lung cancer ranks first in both incidence and mortality among all cancers. Statistics show that lung cancer accounted for 17.9% of newly diagnosed cancers in 2020, and its mortality rate accounted for 27.3% of all cancer deaths in China. Because early-stage lung cancer is insidious and difficult to detect, and 80% of lung cancers diagnosed clinically are already in the middle or late stages, early detection and treatment are crucial for improving the survival rate of lung cancer patients. Clinical research shows that the cure rate for early-stage lung adenocarcinoma is close to 100%, and the success rate is also very high when the diameter of the pulmonary nodule is ≤10mm. Early detection of in situ lung cancer nodules is currently key. Because pulmonary nodules are difficult to see on the lung surface, the success rate of locating the lesion intraoperatively by touch or instrumental gliding is only 30%. Some patients have to be converted to open thoracotomy or even have failed surgery due to inaccurate localization. Therefore, preoperative localization of pulmonary nodules is particularly important.

[0003] Currently, the main techniques for assisted localization of pulmonary nodules include: (1) CT-guided percutaneous puncture assisted localization; (2) bronchoscopic puncture assisted localization; and (3) CT virtual 3D assisted localization.

[0004] CT-guided percutaneous puncture-assisted localization mainly includes percutaneous hookwire localization, percutaneous coil localization, methylene blue localization, and localization using iodized oil or iodine-containing contrast agents.

[0005] Percutaneous hookwire localization: First, a high-resolution CT (HRCT) scan is used to determine the location of the pulmonary nodule. Then, a puncture approach is selected, and the hookwire cannula is inserted percutaneously into the lung tissue. A repeat CT scan is performed to confirm the hookwire is in the target location, and then it is advanced 3–5 mm further. The bevel of the cannula tip is facing the lesion, the wire is released, and the cannula is retrieved. The metal hook at the tip is unfolded and fixed around the nodule. After confirming good anchorage, the wire is loosely bent and tightly wrapped against the skin for fixation. VATS surgery should be performed within 1–2 hours. However, wire displacement and even detachment are the main reasons for hookwire localization failure. Secondly, common complications such as pneumothorax, bleeding, and pain are prone to occur after localization.

[0006] Percutaneous coil placement: The procedure is basically the same as the hookwire placement method. A preoperative CT scan determines the needle insertion route, and the placement point should be <1 cm from the nodule. After a second CT scan confirms the needle placement is correct, the coil is released into the lung. Because it has no barbs, it relies on the friction between the coil and the lung tissue to ensure reliable fixation. Currently, there are two most commonly used coil placement methods: one is to position the coil inside the lung, and the other is to position the tail of the coil outside the visceral pleura.

[0007] Methylene blue localization: Methylene blue aqueous solution appears blue in an oxidizing environment and is commonly used as a chemical indicator, dye, biological stain, and in pharmaceutical applications. This dye not only rapidly identifies the area covered by the target nodule but also does not affect instrument handling and palpation. Preoperative localization is achieved through CT simulation. After anesthesia, methylene blue is injected around the lesion according to the pre-marked puncture site, angle, and depth. Once localization is successful, the patient is transferred to the operating room for surgery, which is performed under thoracoscopy based on the staining localization. However, in practice, methylene blue still has some limitations. On the one hand, methylene blue diffuses rapidly, often requiring clinicians to perform thoracoscopy within 3 hours of injection localization, which can affect surgical scheduling and coordination. On the other hand, its tendency to diffuse and be interfered with increases the localization area on the lung surface, leading to an expansion of the lung resection area.

[0008] Iodized oil and iodine-containing contrast agent localization: Iodized oil is an inexpensive and readily available contrast agent. After injection, it absorbs more X-rays than surrounding tissues, resulting in more satisfactory imaging. It is also excreted from the body faster than barium contrast agents, with a shorter residence time. Iodized oil diffuses more slowly than methylene blue, resulting in stable imaging areas and high localization accuracy. It also has a longer residence time in the lungs, allowing for a relatively ample transition time between the localization room and the operating room. Despite these advantages, iodized oil contrast imaging also has some drawbacks in clinical application. For example, there is a potential risk of pulmonary embolism, and some reports suggest that this method can easily lead to inflammatory reactions in the localized tissues, even pneumonia. Because iodized oil localization requires the surgeon to operate under X-ray fluoroscopy, its clinical use is limited. Furthermore, caution should be exercised in patients with hyperthyroidism, thyroid tumors, severe heart, liver, or lung diseases, acute bronchitis, and fever.

[0009] Bronchoscopic puncture-assisted localization: Electromagnetic navigation bronchoscopy (ENB) is a novel minimally invasive diagnostic technique that has emerged in recent years. Using ENB to guide the marking of solitary pulmonary nodules has been widely applied for preoperative localization of VATS (Vacuum-Assisted Transluminal Surgical Techniques). ENB-guided placement of helical spring reference markers has a better retention rate and a lower complication rate compared to linear reference markers.

[0010] CT Virtual 3D Assisted Positioning: The operating principle is to import the patient's CT data into the navigation computer, and the computer performs image reconstruction and puncture route simulation. Based on the patient's position, the three-dimensional spatial coordinate system of the patient's chest is superimposed with the three-dimensional coordinate system of the CT image to determine the direction and depth of needle insertion. The specific implementation process requires specialized equipment and instruments, which limits its widespread clinical application.

[0011] Chinese invention patent CN103876841B discloses a marker, its manufacturing method, and a positioning system made from the marker. The system includes a head end that provides firm anchoring within lung tissue, a tail end that provides firm anchoring on the visceral pleura of the lung surface, and a middle section between the head and tail ends, the length of which can be selected according to the distance of the space-occupying lesion from the adjacent visceral pleural surface. This patent achieves fixation in the lung by using a coiled spring coil at the head end. However, because it is bent by a single spring wire, the spring wire cannot seal the puncture tube, leading to pulmonary hemorrhage flowing out from the puncture tube. Summary of the Invention

[0012] The purpose of this invention is to overcome the shortcomings of the prior art and provide a lung nodule positioning device and system, which aims to solve the technical problem that the mechanism formed by bending a single spring wire in the prior art has a small radial area in the delivery tube, resulting in large bleeding.

[0013] To achieve the above objectives, the present invention proposes a lung nodule positioning device, comprising a distal end, an intermediate connecting section, and a proximal end, wherein the two sides of the intermediate connecting section are respectively connected to the distal end and the proximal end; characterized in that: the intermediate connecting section has an elastic contraction function, and the distal end includes an anchor hook and a sealing part for connecting the anchor hook and the intermediate connecting section, wherein the sealing part is adapted to the inner diameter of the delivery pipe.

[0014] Preferably, the distal end includes a conveying state and a releasing state; in the conveying state, the distal end is stretched into an elongated body, and the radial distance formed by the anchor hook is not greater than the radial length of the sealing portion; in the releasing state, the anchor hook has an extension extending towards the proximal end, and the radial distance formed by the anchor hook is greater than the radial length of the sealing portion.

[0015] Preferably, in the released state, the anchor hook includes a first curved segment extending distally from the sealing portion and then proximally.

[0016] Preferably, in the released state, the anchor hook includes a first straight segment extending from the sealing portion to the distal end and then to the proximal end.

[0017] Preferably, in the released state, the anchor hook includes a second straight segment extending distally from the blocking portion and a second curved segment extending proximally from the second straight segment; or the anchor hook includes a second straight segment extending distally from the blocking portion and a second curved segment extending proximally from the second curved segment.

[0018] Preferably, in the released state, the anchor hook includes a third straight segment extending distally from the sealing portion and a bent segment connected to the third straight segment, one end of the bent segment extending distally and the other end extending proximally.

[0019] Preferably, the anchor hook is made of a biocompatible metallic material, including one or more of platinum-iridium alloy, platinum-tungsten alloy, cobalt-chromium alloy, and nickel-titanium alloy; the anchor hook is manufactured by one or more of the following processes: plastic shaping, heat shaping, forging, gluing, welding, and riveting.

[0020] Preferably, the proximal end portion includes a conveying state and a releasing state; in the conveying state, the proximal end portion is stretched into an elongated body; in the releasing state, the proximal end portion self-expands into a coiled shape.

[0021] Preferably, in the released state, the proximal end expands into a spiral or clover shape; the proximal end is formed by plastic deformation and heat setting; the proximal end is made of one or more metal wires wound together; the proximal end is made of a biocompatible metallic material, including one or more of platinum-iridium alloy, platinum-tungsten alloy, cobalt-chromium alloy, and nickel-titanium alloy.

[0022] Preferably, the intermediate connecting section is a spring-shaped material made of biocompatible metal, formed by plastic deformation or heat setting; it contains one or more of the following materials: platinum-iridium alloy, platinum-tungsten alloy, cobalt-chromium alloy, and nickel-titanium alloy.

[0023] To achieve the above objectives, the present invention also proposes a lung nodule localization system, which uses a delivery component to deliver the lung nodule localization device into the lung to achieve lung nodule localization.

[0024] Preferably, the conveying component includes a conveying tube for loading the lung nodule positioning device and a push rod for pushing the lung nodule positioning device out of the conveying tube; the conveying tube is provided with multiple graduations.

[0025] Preferably, the push rod is a solid round bar, which pushes the proximal end to achieve release.

[0026] Preferably, the push rod is a hollow tube, the outer diameter of the blocking part is larger than the inner diameter of the push rod, the intermediate connecting section and the proximal end are disposed inside the push rod, and the push rod pushes the distal end to achieve release.

[0027] Compared with the prior art, the beneficial effects of the lung nodule localization device and system provided by the present invention are as follows:

[0028] 1. The positioning device of the present invention has one end fixed at the lesion and the other end not protruding from the chest, and can be fixed on the visceral pleura. The anchor hook fixation at the lesion makes it less prone to displacement of the distal end to the proximal end during respiration.

[0029] 2. The delivery tube can be a puncture needle. Although the puncture needle has a small aperture, it will still cause blood leakage when it enters the human body. The sealing part (the sealing part is solid) reduces the gap between the positioning device and the inside of the puncture needle, thus reducing blood leakage through the puncture needle.

[0030] 3. In the released state, the anchor hook has a larger outward expansion area, making it more stable when fixed at the lesion. In the transport state, it is a slender body with a small radial width, making it easier to transport.

[0031] 4. Anchor hooks come in many shapes, all of which have an extension that extends proximally and has a barbed effect, which increases the stability of the anchor hook and prevents it from falling off during breathing.

[0032] The features and advantages of the present invention will be described in detail through embodiments and in conjunction with the accompanying drawings. Attached Figure Description

[0033] Figure 1 This is a schematic diagram of the released state of a lung nodule positioning device according to an embodiment of the present invention.

[0034] Figure 2 This is a schematic diagram of the delivery state of a lung nodule positioning device according to an embodiment of the present invention.

[0035] Figures 3-14 This is a schematic diagram of the structure of a lung nodule positioning device according to an embodiment of the present invention, showing different anchor hook release states.

[0036] Figure 15 This is a schematic diagram of the transport component of a lung nodule positioning device according to an embodiment of the present invention.

[0037] Figure 16 This is a schematic diagram of the structure of a delivery component release positioning device of a lung nodule positioning device according to an embodiment of the present invention.

[0038] Figure 17 This is a schematic diagram of the release structure of the push rod of the conveying component of a lung nodule positioning device according to an embodiment of the present invention, when it is a solid round bar.

[0039] Figure 18 This is a schematic diagram of the release structure of the push rod of the conveying component of a lung nodule positioning device according to an embodiment of the present invention when it is a hollow tube.

[0040] Figure 19 This is a schematic diagram of the structure of a lung nodule positioning device released into the lungs according to an embodiment of the present invention.

[0041] Figures 20-21 This is a schematic diagram of the proximal end of a lung nodule localization device according to an embodiment of the present invention.

[0042] in:

[0043] 1-Distal end; 11-Anchor hook; 12-Blocking part; 131-First curved segment; 132-First straight segment; 133-Second straight segment; 134-Second curved segment; 135-Third straight segment; 136-Bending segment; 2-Intermediate connecting segment; 3-Proximal end; 4-Conveying pipe; 5-Push rod. Implementation

[0044] To make the objectives, technical solutions, and advantages of this invention clearer, the invention will be further described in detail below with reference to the accompanying drawings and embodiments. However, it should be understood that the specific embodiments described herein are merely illustrative and not intended to limit the scope of the invention. Furthermore, descriptions of well-known structures and technologies are omitted in the following description to avoid unnecessarily obscuring the concept of the invention.

[0045] In the description of this invention, it should be noted that when an element is referred to as being "fixed to" or "set on" another element, it can be directly on or indirectly on the other element. When an element is referred to as being "connected to" another element, it can be directly connected to or indirectly connected to the other element.

[0046] In the description of this invention, it should be noted that the terms "center," "length," "width," "thickness," "upper," "lower," "front," "rear," "left," "right," "vertical," "horizontal," "top," "bottom," "inner," and "outer," etc., indicate the orientation or positional relationship based on the orientation or positional relationship shown in the accompanying drawings, or the orientation or positional relationship commonly used when the product of this invention is in use. They are used only for the convenience of describing the invention and for simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation. Therefore, they should not be construed as limitations on the invention. Furthermore, the terms "first," "second," and "third," etc., are used only to distinguish descriptions and should not be construed as indicating or implying relative importance. Thus, a feature defined as "first" or "second" may explicitly or implicitly include one or more of that feature. In the description of this invention, "a plurality of" means two or more, unless otherwise explicitly specified. "Several" means one or more, unless otherwise explicitly specified.

[0047] In the description of this invention, it should also be noted that, unless otherwise explicitly specified and limited, the terms "set," "install," "connect," and "link" should be interpreted broadly. For example, they can refer to a fixed connection, a detachable connection, or an integral connection; they can refer to a mechanical connection or an electrical connection; they can refer to a direct connection or an indirect connection through an intermediate medium; and they can refer to the internal connection of two components. Those skilled in the art can understand the specific meaning of the above terms in this invention based on the specific circumstances.

[0048] Embodiments of this disclosure will now be described in detail with reference to the accompanying drawings. As used herein, the term "clinician" refers to a physician, surgeon, nurse, or any other care provider, and may include assistants. The term "proximal" will refer to the portion of the device or its components closer to the clinician, and the term "distal" will refer to the portion of the device or its components further away from the clinician.

[0049] See Figure 1 This invention provides a lung nodule localization device, comprising a distal end 1, an intermediate connecting section 2, and a proximal end 3. The two sides of the intermediate connecting section 2 are respectively connected to the distal end 1 and the proximal end 3. The intermediate connecting section 2 has an elastic contraction function. The distal end 1 includes an anchor hook 11 and a sealing part 12 for connecting the anchor hook 11 and the intermediate connecting section 2. The sealing part 12 is adapted to the inner diameter of the delivery tube 4. This adaptation does not necessarily have to be similar to the inner diameter of the delivery tube 4, as long as it can provide a larger sealing area relative to the intermediate connecting section 2. The anchor hook 11 is fixed at the lesion site, forming a barbed structure that is not easily displaced. The sealing part 12 is solid, which, compared to the hollow intermediate connecting section 2, allows for a smaller gap between the sealing part 12 and the delivery tube 4, making it less likely for blood to flow out of the delivery tube 4.

[0050] See Figure 1 and Figure 2In an optional embodiment, the distal end 1 includes a delivery state and a release state. In the delivery state, the distal end 1 is stretched into an elongated body, which facilitates delivery within the delivery tube 4. The radial distance formed by the anchor hook 11 is not greater than the radial length of the occlusion portion 12. An excessively large radial distance formed by the anchor hook 11 will affect delivery and implantation, and may also lead to increased bleeding. When the radial distance of the anchor hook 11 increases, a larger delivery tube 4 (which could be a puncture needle) is required. With the radial distance of the occlusion portion 12 remaining constant, the gap between the occlusion portion 12 and the delivery tube 4 increases, making it easier for blood to flow out of the delivery tube 4. In the release state, the anchor hook 11 has an extension extending proximally, and the radial distance formed by the anchor hook 11 is greater than the radial length of the occlusion portion 12. After the positioning device is implanted in the lung, the lung contracts due to respiration, and the length of the intermediate connecting section 2 changes. The extension acts like a barb, preventing the distal end 1 from moving proximally or falling off. A larger radial distance after the anchor hook 11 is released improves fixation and prevents falling off. Figure 19 .

[0051] The anchor hook 11 has many structures. The following is a description of the different structures of the anchor hook 11 with reference to the attached drawings.

[0052] See Figures 3-4 In an optional embodiment, in the released state, the anchor hook 11 includes a first curved segment 131 extending distally and then proximally from the sealing portion 12. The first curved segment 131 can be a semicircle or a quarter circle. Preferably, it is a quarter circle, with the proximal end of the anchor hook 11 being an arc segment. This provides a larger contact area with the lungs during lung expansion and contraction, making it less likely to detach or cause significant bleeding. Of course, the angle of the first curved segment 131 can be arbitrary, as long as there is a portion extending proximally. The number of anchor hooks 11 can be one or more, evenly distributed at the distal end of the sealing portion 12. The anchor hook 11 can be a two-dimensional or three-dimensional structure. Figures 12-14 This is a top view of a two-dimensional structure with 2-4 anchor hooks 11. Figures 9-11 This is a top view of a three-dimensional structure with 2-4 anchor hooks 11. Anchor hooks with a three-dimensional mechanism are preferred, as they have more contact points in space and a more stable structure.

[0053] See Figure 5 In an optional embodiment, the anchor hook 11 includes a first straight segment 132 extending distally and proximally from the sealing portion 12, generally forming a V-shape. This type of anchor hook 11 can be a two-dimensional or three-dimensional structure.

[0054] See Figure 6 In an optional embodiment, in the released state, the anchor hook 11 includes a second straight segment 133 extending distally from the blocking portion 12 and a second curved segment 134 extending proximally from the second straight segment 133. Or as...Figure 7 The anchor hook 11 includes a second straight segment 133 extending distally from the sealing portion 12 and extending proximally from the second curved segment 134. The anchor hook 11 can be a two-dimensional or three-dimensional structure.

[0055] See Figure 8 In an optional embodiment, in the released state, the anchor hook 11 includes a third straight segment 135 extending distally from the sealing portion 12 and a bent segment 136 connected to the third straight segment 135. One end of the bent segment 136 extends distally, and the other end extends proximally. The bent segment 136 is preferably semi-circular, with one half extending proximally and the other half distally. This structure serves both to prevent the device from moving proximally and to increase the positioning volume by extending distally. Furthermore, the area connected to the sealing portion 12 is smaller, allowing for the connection of a larger number of anchor hooks.

[0056] In an optional embodiment, the anchor hook 11 is made of a biocompatible metallic material, including one or more of platinum-iridium alloy, platinum-tungsten alloy, cobalt-chromium alloy, and nickel-titanium alloy. The anchor hook 11 is manufactured by one or more of the following processes: plastic shaping, heat shaping, forging, gluing, welding, and riveting.

[0057] See Figure 1 and Figure 2 In an optional embodiment, the proximal end portion 3 includes a conveying state and a releasing state. In the conveying state, the proximal end portion 3 is stretched into an elongated body. In the releasing state, the proximal end portion 3 self-expands into a coiled shape.

[0058] See Figures 20-21 In an optional embodiment, in the released state, the proximal end portion 3 expands into a spiral or clover shape. These shapes have a large contact area, better fixation, are less prone to detachment, and provide better marking. The proximal end portion 3 is formed by plastic deformation and heat setting. The proximal end portion 3 is made of one or more metal wires wound together, or wound into a spring shape using metal wires. The proximal end portion 3 is made of a biocompatible metallic material, including one or more of platinum-iridium alloy, platinum-tungsten alloy, cobalt-chromium alloy, and nickel-titanium alloy.

[0059] See Figure 1 In an optional embodiment, the intermediate connecting segment 2 is a spring-shaped component made of a biocompatible metallic material, formed through plastic deformation or thermosetting. The intermediate connecting segment 2 has elastic contractile properties, allowing the anchoring and positioning component to contract with the breathing of the lung tissue without causing pain or discomfort to the patient. It contains one or more materials selected from platinum-iridium alloy, platinum-tungsten alloy, cobalt-chromium alloy, and nickel-titanium alloy.

[0060] The middle connecting section 2 is connected to the distal intrapulmonary anchor hook (distal end 1) and the proximal extrapulmonary position marker (proximal end 3) at both ends. The three parts can be stably connected by forging, gluing, welding, riveting and other processes to form an anchoring and positioning component.

[0061] like Figure 15 A lung nodule localization system can deliver any lung nodule localization device into the lungs via a delivery component to achieve lung nodule localization. Furthermore, it can deliver any of the lung nodule localization devices described in the above embodiments.

[0062] See Figure 16 In an optional embodiment, the delivery component includes a delivery tube 4 for loading the lung nodule positioning device and a push rod 5 for pushing the lung nodule positioning device out of the delivery tube 4. The delivery tube 4 can be a puncture needle, and the delivery tube 4 has multiple graduations for identification.

[0063] See Figure 17 In an optional embodiment, the push rod 5 is a solid round bar that pushes the proximal end 3 to achieve release. Preferably, the diameter of the push rod 5 is larger than the diameter of the proximal end 3, resulting in a larger contact area and a better pushing effect.

[0064] See Figure 18 In an optional embodiment, the push rod 5 is a hollow tube, the outer diameter of the blocking part 12 is larger than the inner diameter of the push rod 5, the intermediate connecting section 2 and the proximal end 3 are disposed within the push rod 5, and the push rod 5 pushes the distal end 1 to release it. During the pushing process, the distal end of the push rod 5 abuts against the proximal end of the blocking part 12, the intermediate connecting section 2 is inside the push rod 5, and the positioning device is slowly pushed out of the delivery tube 4 for release.

[0065] The procedure by which clinicians use a lung nodule localization system during surgery is as follows:

[0066] 1. Under CT guidance, clinicians use a puncture needle to puncture the chest wall and enter the lung, then deliver the lung nodule localization device to the edge of the lesion.

[0067] 2. The clinician pushes the distal end 1 out of the puncture needle through the push rod 5, and the anchor hook 11 is released and inserted into the lesion, and fixed in the lung through the pre-set structure.

[0068] 3. Keep the pusher 5 in place and slowly withdraw the puncture needle, allowing the intermediate connecting segment 2 to be released naturally into the lung.

[0069] 4. When the distal end of the puncture needle is outside the lung, keep the puncture needle still and push the push rod 5 to release the proximal end 3, so that it is naturally coiled on the outer surface of the lung and fixed on the visceral pleura.

[0070] 5. During the procedure, under video-assisted laparoscopy, the clinician determines the location of the lesion by observing the position of the extrapulmonary landmark (proximal 3), removes the lesion using a wedge resection, and removes the lesion and the lung nodule localization instrument together (e.g., Figure 19 (As shown).

[0071] The above description is only a preferred embodiment of the present invention and is not intended to limit the present invention. Any modifications, equivalent substitutions or improvements made within the spirit and principles of the present invention should be included within the protection scope of the present invention.

Claims

1. A lung nodule localization device, comprising a distal end (1), an intermediate connecting segment (2), and a proximal end (3), wherein the two sides of the intermediate connecting segment (2) are respectively connected to the distal end (1) and the proximal end (3); characterized in that: The intermediate connecting section (2) has an elastic contraction function. The distal end (1) includes an anchor hook (11) and a sealing part (12) for connecting the anchor hook (11) and the intermediate connecting section (2). The sealing part (12) is adapted to the inner diameter of the conveying pipe (4). The sealing part (12) is solid and has a larger sealing area than the intermediate connecting section (2). The distal end (1) includes a conveying state and a release state. In the conveying state, the distal end (1) is stretched into an elongated body, and the radial distance formed by the anchor hook (11) is not greater than the radial length of the sealing part (12). In the release state, the anchor hook (11) has an extension extending towards the proximal end, and the radial distance formed by the anchor hook (11) is greater than the radial length of the sealing part (12). In the released state, the anchor hook (11) includes a third straight segment (135) extending distally from the sealing part (12) and a bent segment (136) connected to the third straight segment (135), one end of the bent segment (136) extending distally and the other end extending proximally.

2. The lung nodule localization device as described in claim 1, characterized in that: The anchor hook (11) is made of a biocompatible metallic material, including one or more of platinum-iridium alloy, platinum-tungsten alloy, cobalt-chromium alloy, and nickel-titanium alloy; the anchor hook (11) is prepared by one or more of the following processes: plastic shaping, heat shaping, forging, gluing, welding, and riveting.

3. The lung nodule localization device as described in claim 1, characterized in that: The proximal end (3) includes a conveying state and a releasing state; in the conveying state, the proximal end (3) is stretched into an elongated body; in the releasing state, the proximal end (3) expands into a coiled shape.

4. The lung nodule localization device as described in claim 3, characterized in that: In the released state, the proximal end (3) expands into a spiral or clover shape; the proximal end (3) is formed by plastic deformation and heat setting; the proximal end (3) is made of one or more metal wires wound together; the proximal end (3) is made of a biocompatible metal material, including one or more of platinum-iridium alloy, platinum-tungsten alloy, cobalt-chromium alloy, and nickel-titanium alloy.

5. The lung nodule localization device as described in claim 1, characterized in that: The intermediate connecting section (2) is a spring-shaped material made of biocompatible metal material, formed by plastic deformation or heat setting process; it contains one or more of the following materials: platinum-iridium alloy, platinum-tungsten alloy, cobalt-chromium alloy, and nickel-titanium alloy.

6. A lung nodule localization system, characterized in that: The lung nodule localization device according to any one of claims 1-5 is delivered into the lung via a delivery component to achieve lung nodule localization.

7. A lung nodule localization system as described in claim 6, characterized in that: The delivery component includes a delivery tube (4) for loading the lung nodule positioning device and a push rod (5) for pushing the lung nodule positioning device out of the delivery tube (4); the delivery tube (4) is provided with multiple scales.

8. A lung nodule localization system as described in claim 7, characterized in that: The push rod (5) is a solid round rod, which pushes the proximal end (3) to release.

9. A lung nodule localization system as described in claim 7, characterized in that: The push rod (5) is a hollow tube. The outer diameter of the sealing part (12) is larger than the inner diameter of the push rod (5). The intermediate connecting section (2) and the proximal end (3) are arranged inside the push rod (5). The push rod (5) pushes the distal end (1) to release.

Images