A pipette tip box with internal cushioning and method of operation

Abstract

The application discloses a pipette tip box with an internal buffering structure and an operation method thereof, and aims to provide a pipette tip box with an internal buffering structure, simple structure and high practicability, and technical scheme is as follows: the tip placing seat is in sliding connection with the box body, when the box body is shaken, the tip placing seat will form relative movement on the box body, and the internal buffering structure is arranged between the box body and the tip placing seat, so that the tip placing seat is buffered when the tip placing seat and the box body form relative movement, buffering support of the tip placing seat is improved, shaking of the tip is reduced, and the internal buffering structure is further arranged to include a buffering cavity arranged on the bottom of the tip placing seat and a buffering structure arranged in the buffering cavity, the buffering cavity is used as a main buffering means, so that good internal buffering effect of the tip placing seat is achieved, and the application is suitable for the technical field of medical equipment.

Description

Technical Field

[0001] This invention relates to the field of medical device technology, and more specifically, to a pipette tip box with an internal buffer structure and its operating method. Background Technology

[0002] A pipette is a commonly used device in biochemistry experiments. Its working principle is that the piston achieves liquid aspiration and dispensing through the extension and retraction of the spring. Under the push of the piston, some air is expelled, and liquid is drawn in using atmospheric pressure. Then, the piston pushes the air to expel the liquid. When using a pipette, the extension and retraction characteristics of the spring can be used to operate it, which can effectively control the speed and force of pipetting.

[0003] The correct use of a pipette requires the use of the correct and appropriate pipette tip. For liquids that are not very viscous (such as water and other thin solutions), it is convenient, quick and accurate to use the commercially available matching pipette tip (the diameter of the pipette tip's aspiration port is 5mm).

[0004] The pipette tip box is used to hold pipette tips. Traditionally, the box and tip holder are an integrated structure. During pipetting and transportation, vibration of the box can easily cause the tips to shake, resulting in the sampled liquid flowing out of the tip and affecting subsequent use. Summary of the Invention

[0005] In view of the shortcomings of the existing technology, the purpose of this invention is to provide a pipette tip box with an internal buffer structure, simple structure and strong practicality.

[0006] To achieve the above objectives, the present invention provides the following technical solution: a pipette tip box with an internal buffer structure, comprising a box body, a box cover rotatably connected to the box body, and a pipette tip holder placed inside the box body. The pipette tip holder and the box body are slidably connected. An internal buffer structure is provided between the box body and the pipette tip holder. The internal buffer structure includes a buffer cavity disposed on the bottom of the pipette tip holder, a pressure-reducing structure disposed in the buffer cavity, an upper cavity connected to the buffer cavity and perpendicular to the bottom of the pipette tip holder, a lower cavity connected to the buffer cavity and perpendicular to the upper cavity, a lower conduction structure disposed in the upper cavity, and an upper conduction structure disposed in the lower cavity and abutting against the side wall of the box body.

[0007] The present invention is further configured such that: the lower conduction structure includes an upper piston disposed in the upper cavity and an upper abutment plate disposed on the upper piston; the upper conduction structure includes a lower piston disposed in the lower cavity, a lower abutment plate disposed on the lower piston, and a return spring sleeved outside the lower piston rod and placed in the lower cavity.

[0008] The present invention is further configured such that: the pressure-relieving structure includes a main shaft structure disposed in the buffer cavity and a buffer impeller rotatably connected to the main shaft structure.

[0009] The present invention is further configured such that: a sliding mechanism is provided between the suction head placement seat and the box body, the sliding mechanism including a slider disposed in the box body and a slide rail disposed on the suction head placement seat and adapted to the slider, the slider having a trapezoidal cross-section.

[0010] The present invention is further configured such that: the pressure-relieving structure further includes a side buffer section disposed near the buffer impeller, wherein a first conical ring and a second conical ring are respectively disposed on the inner wall of the side buffer section, and the height of the first conical ring is greater than the height of the second conical ring, and the small diameter ends of the first conical ring and the second conical ring both face the buffer impeller side.

[0011] The present invention is further configured such that: the height of the first conical ring is H1, the height of the second conical ring is H2, the distance between the first conical ring and the second conical ring is H3, and the ratio of H1:H2:H3 is 3:1:3 or the ratio of H1:H2:H3 is 3:2:2.

[0012] By adopting the above technical solution, the following beneficial effects are achieved: 1. By using a sliding connection between the suction head placement seat and the box body, the suction head placement seat will move relative to the box body when the box body is vibrated. Furthermore, by providing an internal buffer structure between the box body and the suction head placement seat, the suction head placement seat is buffered when it moves relative to the box body, improving the buffer support for the suction head placement seat and reducing the shaking of the suction head. The internal buffer structure is further configured as follows: a buffer cavity is set on the bottom of the suction head placement seat; a pressure-reducing structure is set in the buffer cavity; an upper cavity is connected to the buffer cavity and perpendicular to the bottom of the suction head placement seat; a lower cavity is connected to the buffer cavity and perpendicular to the upper cavity; a lower conduction structure is set in the upper cavity; and an upper conduction structure is set in the lower cavity and abuts against the side wall of the box body. By using the buffer cavity as the main buffering means, combined with the upper and lower cavities on both sides and the upper and lower conduction structures, a good internal buffering effect is achieved for the suction head placement seat, resulting in strong stability and a simple structure.

[0013] 2. Furthermore, by setting the lower transmission structure to include an upper piston and an upper abutment plate in the upper cavity, a lower piston and a lower abutment plate in the lower cavity, and a return spring sleeved outside the lower piston rod and placed in the lower cavity, when the upper piston is subjected to force, the hydraulic oil in the cavity will be pushed downward. Because the pressure relief structure includes a main shaft structure in the buffer cavity and a buffer impeller rotatably connected to the main shaft structure, the hydraulic oil forms a first buffering effect when passing through the buffer impeller, thereby achieving a buffering effect on the suction head placement seat, improving overall stability, practicality, and simple structure. Moreover, when the force is transmitted to the lower cavity, the return spring in the lower cavity will form a second buffering effect on the hydraulic oil. After the force is canceled out, the return spring returns to its original position, and then the buffer structure forms a third buffering effect, which reduces the force acting on the suction head placement seat, resulting in strong stability and simple structure.

[0014] 3. Further, by setting the pressure-reducing structure to include a side buffer section near the buffer impeller, the inner wall of the side buffer section is provided with a first conical ring and a second conical ring, and the height of the first conical ring is greater than the height of the second conical ring, and the small diameter ends of the first conical ring and the second conical ring are both facing the buffer impeller. The structure of the first and second conical rings forms a constricted buffer for the hydraulic oil, reducing the impact of oil pressure, ensuring the buffering of the suction head placement seat, with strong stability and simple structure;

[0015] 4. By setting the height of the first conical ring to H1, the height of the second conical ring to H2, and the distance between the first and second conical rings to H3, and setting the ratio of H1:H2:H3 to 3:1:3 or H1:H2:H3 to 3:2:2, the continuous lengthening of the buffer space and the formation of two-stage buffers can achieve a good spacing effect, strong stability, simple structure, and improved overall buffering effect.

[0016] A method for operating a pipette tip box with an internal buffer structure as described above includes the following steps: S1, placing the pipette tip into the pipette tip box;

[0017] S2. When the pipette tip box is vibrated, the pipette tip holder and the pipette tip box body move relative to each other. The pipette tip holder moves downward, which puts pressure on the upper piston in the upper chamber. The upper piston pushes the hydraulic oil in the chamber.

[0018] S3. The hydraulic oil forms the first buffer in the side buffer section. The first and second conical rings form two tightening and releasing processes on the hydraulic oil before entering the buffer cavity.

[0019] S4. When hydraulic oil enters the buffer chamber, as the buffer impeller rotates under force, the buffer impeller forms a second buffer on the hydraulic oil and enters the lower chamber.

[0020] S5. When the hydraulic oil is in the lower chamber, it applies pressure to the lower piston, and the return spring in the lower chamber provides three buffers to the lower piston. When the pressure phase ends.

[0021] S6. After the pressure stage ends, the lower piston is reset by the reset spring, and the hydraulic oil in the cavity is also reset, and forms a secondary buffer through the buffer impeller and the side buffer section.

[0022] S7. The suction head placement seat is reset, and the reset phase is complete.

[0023] By adopting the above technical solution, beneficial effects are achieved. Through the internal buffer structure, an elastic support effect is formed for the suction head placement seat when the suction head placement seat and the box body are in relative motion. Furthermore, by forming a three-level buffer effect with the side buffer section, buffer cavity, and return spring, and then buffering twice more through the buffer cavity and side buffer section during reset, a good buffering effect is achieved. Attached Figure Description

[0024] Figure 1 This is a three-dimensional structural diagram of an embodiment of a pipette tip box with an internal buffer structure and its operation method according to the present invention.

[0025] Figure 2 This is a cross-sectional view of the pipette tip box with an internal buffer structure and its operation method according to an embodiment of the present invention.

[0026] In the attached diagram, the following labels are used: 1. Box body; 2. Box cover; 3. Suction head placement seat; 30. Buffer cavity; 301. Main shaft structure; 302. Buffer impeller; 31. Upper cavity; 310. Upper piston; 311. Upper contact plate; 32. Lower cavity; 320. Lower piston; 321. Lower contact plate; 322. Return spring; 40. Side buffer section; 401. First conical ring; 402. Second conical ring. Detailed Implementation

[0027] Reference Figures 1 to 2 The present invention provides a further description of an embodiment of a pipette tip box with an internal buffer structure and its operation method.

[0028] For ease of explanation, spatial relative terms such as “up,” “down,” “left,” and “right” are used in the embodiments to describe the relationship of one element or feature shown in the figures relative to another element or feature. It should be understood that, in addition to the orientations shown in the figures, spatial terms are intended to include different orientations of the device in use or operation. For example, if the device in the figures is inverted, an element described as being “down” of other elements or features would be positioned “up” of those other elements or features. Therefore, the exemplary term “down” can encompass both up and down orientations. The device may be positioned in other ways (rotated 90 degrees or in other orientations), and the spatial relative descriptions used herein will be interpreted accordingly.

[0029] Moreover, relational terms such as “first” and “second” are used merely to distinguish one component from another that has the same name, without necessarily requiring or implying any such actual relationship or order between the components.

[0030] A pipette tip holder with an internal buffer structure includes a box body 1, a box cover 2 rotatably connected to the box body 1, and a pipette tip holder 3 placed inside the box body 1. The pipette tip holder 3 and the box body 1 are slidably connected. An internal buffer structure is provided between the box body 1 and the pipette tip holder 3. The internal buffer structure includes a buffer cavity 30 disposed on the bottom of the pipette tip holder 3, a pressure-relieving structure disposed within the buffer cavity 30, an upper cavity 31 connected to the buffer cavity 30 and perpendicular to the bottom of the pipette tip holder 3, a lower cavity 32 connected to the buffer cavity 30 and perpendicular to the upper cavity 31, a lower conduction structure disposed within the upper cavity 31, and an upper conduction structure disposed within the lower cavity 32 and abutting against the side wall of the box body 1. By slidingly connecting the suction head holder 3 and the housing 1, the suction head holder 3 will move relative to the housing 1 when the housing 1 is vibrated. Furthermore, by providing an internal buffer structure between the housing 1 and the suction head holder 3, the relative movement between the suction head holder 3 and the housing 1 is buffered, improving the buffer support for the suction head holder 3 and reducing the shaking of the suction head. This internal buffer structure further includes a buffer cavity 30 located at the bottom of the suction head holder 3 and a buffer cavity 3... The pressure-reducing structure inside the 0, the upper cavity 31 connected to the buffer cavity 30 and perpendicular to the bottom of the suction head placement seat 3, the lower cavity 32 connected to the buffer cavity 30 and perpendicular to the upper cavity 31, the lower conduction structure set in the upper cavity 31, and the upper conduction structure set in the lower cavity 32 and abutting against the side wall of the box 1, with the buffer cavity 30 as the main buffering means, together with the upper and lower cavities 32 on both sides and the upper and lower conduction structures, achieve a good internal buffering effect on the suction head placement seat 3, with strong stability and simple structure.

[0031] The present invention is further configured such that the lower conducting structure includes an upper piston 310 disposed in the upper cavity 31 and an upper abutment plate 311 disposed on the upper piston 310; the upper conducting structure includes a lower piston 320 disposed in the lower cavity 32, a lower abutment plate 321 disposed on the lower piston 320; and a return spring 322 sleeved outside the rod of the lower piston 320 and placed inside the lower cavity 32. Furthermore, by configuring the lower conducting structure to include an upper piston 310 disposed in the upper cavity 31 and an upper abutment plate 311 disposed on the upper piston 310, and the upper conducting structure to include a lower piston 320 disposed in the lower cavity 32, a lower abutment plate 321 disposed on the lower piston 320, and a return spring 322 sleeved outside the rod of the lower piston 320 and placed inside the lower cavity 32, the invention further supports the following configurations. When the upper piston 310 is under force, the hydraulic oil in the cavity is pushed downward by the return spring 322. Because the pressure relief structure includes the main shaft structure 301 set in the buffer cavity 30 and the buffer impeller 302 rotatably connected to the main shaft structure 301, the hydraulic oil forms a first buffer effect when passing through the buffer impeller 302, thereby achieving a buffer effect on the suction head placement seat 3, improving the overall stability, practicality, and simple structure. Furthermore, when the force is transmitted to the lower cavity 32, the return spring 322 in the lower cavity 32 will form a second buffer on the hydraulic oil. After the force is canceled out, the return spring 322 resets, and then the buffer structure forms a third buffer, which reduces the force acting on the suction head placement seat 3, resulting in strong stability and a simple structure.

[0032] The present invention is further configured such that a sliding mechanism is provided between the suction head placement seat 3 and the box body 1. The sliding mechanism includes a slider disposed in the box body 1 and a slide rail disposed on the suction head placement seat 3 and adapted to the slider. With the above structure, the suction head placement seat 3 slides in the box body 1, which has a good positioning effect, simple structure, and strong stability. The cross-section of the slider is trapezoidal, and the trapezoidal structure has a large contact area, more uniform force distribution, and strong practicality.

[0033] The invention is further configured such that the pressure-reducing structure also includes a side buffer section 40 located near the buffer impeller 302. A first conical ring 401 and a second conical ring 402 are respectively provided on the inner wall of the side buffer section 40, and the height of the first conical ring 401 is greater than the height of the second conical ring 402. The small-diameter ends of both the first conical ring 401 and the second conical ring 402 face towards the buffer impeller 302. Furthermore, by further configuring the pressure-reducing structure to include a side buffer section 40 located near the buffer impeller 302, with the first conical ring 401 and the second conical ring 402 respectively provided on the inner wall of the side buffer section 40, and the height of the first conical ring 401 being greater than the height of the second conical ring 402, and the small-diameter ends of both the first conical ring 401 and the second conical ring 402 facing towards the buffer impeller 302, the first and second conical ring structures form a constricted buffer for the hydraulic oil, reducing the impact of oil pressure and ensuring the buffering effect on the suction head placement seat 3. This results in strong stability and a simple structure.

[0034] The present invention is further configured such that the height of the first conical ring 401 is H1, the height of the second conical ring 402 is H2, and the distance between the first conical ring 401 and the second conical ring 402 is H3, with the ratio of H1:H2:H3 being 3:1:3 or 3:2:2. By setting the height of the first conical ring 401 to H1, the height of the second conical ring 402 to H2, and the distance between the first conical ring 401 and the second conical ring 402 to H3, and setting the ratio of H1:H2:H3 to 3:1:3 or 3:2:2, the continuous lengthening of the buffer space and the formation of two-stage buffers can achieve a good spacing effect, strong stability, simple structure, and improved overall buffering effect.

[0035] A method for operating a pipette tip box with an internal buffer structure as described above includes the following steps: S1, placing the pipette tip into the pipette tip box;

[0036] S2. When the pipette tip box is vibrated, the pipette tip holder 3 and the pipette tip box 1 move relative to each other. The pipette tip holder 3 moves downward, which puts pressure on the upper piston 310 in the upper cavity 31. The upper piston 310 pushes the hydraulic oil in the cavity.

[0037] S3. The hydraulic oil forms the first buffer in the side buffer section 40. The first and second conical rings form a tightening and releasing process on the hydraulic oil twice before entering the buffer cavity.

[0038] S4. When the hydraulic oil enters the buffer chamber, as the buffer impeller 302 rotates under force, the buffer impeller 302 forms a second buffer for the hydraulic oil and enters the lower chamber 32.

[0039] S5. When the hydraulic oil is in the lower chamber 32, it applies pressure to the lower piston 320. The return spring 322 in the lower chamber 32 provides three buffering cycles to the lower piston 320. When the pressure-bearing phase ends.

[0040] S6. After the pressure stage ends, the lower piston 320 is reset by the return spring 322, and the hydraulic oil in the cavity is also reset, and forms a secondary buffer through the buffer impeller 302 and the side buffer section 40.

[0041] S7. The suction head placement seat 3 is reset, and the reset phase is complete.

[0042] By adopting the above technical solution, the beneficial effects are achieved. Through the internal buffer structure, an elastic support effect is formed on the suction head placement seat 3 when the suction head placement seat 3 and the box body 1 are in relative motion. Furthermore, by forming a three-level buffer effect through the side buffer section 40, the buffer cavity 30, and the return spring 322, and then through the buffer cavity and the side buffer section 40 during reset, a good buffering effect is achieved.

[0043] The above description is only a preferred embodiment of the present invention and is not intended to limit the present invention. Any ordinary changes and substitutions made by those skilled in the art within the scope of the technical solution of the present invention should be included within the protection scope of the present invention.

Claims

1. A pipette tip box with an internal buffer structure, comprising a box body (1), a box cover (2) rotatably connected to the box body (1), and a pipette tip holder (3) placed inside the box body (1), characterized in that, The suction head holder (3) and the box body (1) are slidably connected. An internal buffer structure is provided between the box body (1) and the suction head holder (3). The internal buffer structure includes a buffer cavity (30) disposed on the bottom of the suction head holder (3), a pressure-relieving structure disposed in the buffer cavity (30), an upper cavity (31) connected to the buffer cavity (30) and perpendicular to the bottom of the suction head holder (3), a lower cavity (32) connected to the buffer cavity (30) and perpendicular to the upper cavity (31), a lower conduction structure disposed in the upper cavity (31), and an upper conduction structure disposed in the lower cavity (32) and abutting against the side wall of the box body (1). The lower conduction structure includes an upper piston (310) disposed in the upper cavity (31) and an upper abutment plate (311) disposed on the upper piston (310). The upper conduction mechanism includes a lower piston (320) disposed in the lower cavity (32), a lower abutment plate (321) disposed on the lower piston (320), and a return spring (322) sleeved outside the rod of the lower piston (320) and placed in the lower cavity (32). The pressure relief structure includes a main shaft structure (301) disposed in the buffer cavity (30) and a buffer impeller (302) rotatably connected to the main shaft structure (301). The pressure relief structure also includes a buffer impeller (302) located near the buffer impeller (302). A side buffer section (40) is provided, and a first conical ring (401) and a second conical ring (402) are respectively provided on the inner wall of the side buffer section (40). The height of the first conical ring (401) is greater than the height of the second conical ring (402). The small diameter ends of the first conical ring (401) and the second conical ring (402) are both facing the buffer impeller (302). The height of the first conical ring (401) is H1, the height of the second conical ring (402) is H2, and the distance between the first conical ring (401) and the second conical ring (402) is H3. The ratio of H1:H2:H3 is 3:1:3 or the ratio of H1:H2:H3 is 3:2:

2.

2. The pipette tip box with an internal buffer structure according to claim 1, characterized in that, A sliding mechanism is provided between the suction head placement seat (3) and the box body (1). The sliding mechanism includes a slider disposed in the box body (1) and a slide rail disposed on the suction head placement seat (3) and adapted to the slider. The cross-section of the slider is trapezoidal.

3. A method for operating a pipette tip box with an internal buffer structure as described in any one of claims 1-2, characterized in that, The steps include the following: S1, Place the pipette tip into the pipette tip box; S2. When the pipette tip box is vibrated, the pipette tip holder (3) and the pipette tip box body (1) move relative to each other. The pipette tip holder (3) moves downward and exerts pressure on the upper piston (310) in the upper cavity (31). The upper piston (310) pushes the hydraulic oil in the cavity. S3. The hydraulic oil forms the first buffer in the side buffer section (40). The first and second conical rings form a tightening and releasing process on the hydraulic oil twice before entering the buffer cavity (30). S4. When the hydraulic oil enters the buffer chamber (30), as the buffer impeller (302) rotates under force, the buffer impeller (302) forms a second buffer on the hydraulic oil and enters the lower chamber (32). S5. When the hydraulic oil is in the lower chamber (32), it applies pressure to the lower piston (320), and the return spring (322) in the lower chamber (32) buffers the lower piston (320) three times. When the pressure stage ends. S6. After the pressure stage ends, the lower piston (320) is reset by the return spring (322), and the hydraulic oil in the cavity is also reset, and forms a secondary buffer through the buffer impeller (302) and the side buffer section (40). S7. The suction head placement seat (3) is reset, and the reset phase is completed.

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