Methods and devices for quantitative assessment of left ventricular outflow tract obstruction and aortic stenosis

Abstract

This invention relates to a method and apparatus for quantitatively assessing left ventricular outflow tract obstruction and aortic stenosis. The method includes acquiring the outflow tract pressure gradient and cardiac output; determining the relationship between cardiac output and outflow tract pressure gradient using Bernoulli's equation; calculating the cardiac obstruction coefficient based on the equation; the cardiac obstruction coefficient includes the cardiac obstruction coefficient from the left ventricular cavity to the outflow tract segment and the cardiac obstruction coefficient from the outflow tract to the ascending aorta; and assessing the patient's obstruction status based on the cardiac obstruction coefficient. The cardiac obstruction coefficient calculated by this invention is mainly determined by the morphology of the patient's blood flow cavity and is not affected by cardiac output, thus providing a more accurate description of the patient's obstruction status. This helps physicians make more accurate clinical judgments.

Description

Technical Field

[0001] This invention belongs to the field of medical technology, specifically relating to a method and apparatus for quantitatively assessing left ventricular outflow tract obstruction and aortic stenosis. Background Technology

[0002] When the left ventricular outflow tract becomes obstructed, symptoms such as fatigue, shortness of breath, exercise intolerance, palpitations, and syncope may occur. In the most severe cases, it can lead to sudden cardiac death. Currently, the main clinical method for quantitatively describing cardiac outflow tract obstruction and aortic stenosis is the pressure gradient calculated based on the maximum flow velocity measured by color Doppler ultrasound. Another method is to use catheters to measure the pressure gradient from the left ventricular cavity to the aortic segment to assess the patient's obstruction status.

[0003] While color Doppler ultrasound is widely used in related technologies, its clinical application in assessing outflow tract obstruction and aortic stenosis exhibits significant fluctuations. The pressure differential calculated from the ultrasound-measured blood flow velocity at the outflow tract is primarily based on an idealized Bernoulli equation, with some simplification. Considering the complex factors influencing the maximum blood flow velocity at the outflow tract and aortic valve, this may introduce errors into the clinical diagnosis of outflow tract obstruction and aortic stenosis. Further derivation of the basic fluid dynamics formulas used in ultrasound is needed to clarify the influence of various factors on the measured flow velocity and the calculated pressure differential, thereby obtaining more reliable criteria for assessing outflow tract obstruction and aortic stenosis. Furthermore, catheter-based pressure differential measurement methods are less clinically used than color Doppler ultrasound due to their invasiveness and cost.

[0004] In summary, existing technologies for assessing cardiac outflow tract obstruction and aortic stenosis have certain errors and are not accurate enough. Summary of the Invention

[0005] In view of this, the purpose of the present invention is to overcome the shortcomings of the prior art and provide a method and apparatus for quantitatively assessing left ventricular outflow tract obstruction and aortic stenosis, so as to solve the problem that the assessment methods for cardiac outflow tract obstruction and aortic stenosis in the prior art have certain errors and are not accurate enough.

[0006] To achieve the above objectives, the present invention adopts the following technical solution: a method for quantitatively assessing left ventricular outflow tract obstruction and aortic stenosis, comprising:

[0007] Obtain the outflow tract pressure differential and cardiac output, and use Bernoulli's equation to determine the relationship between the cardiac output and the outflow tract pressure differential.

[0008] The cardiac obstruction coefficient is calculated based on the aforementioned relational equation; the cardiac obstruction coefficient includes the cardiac obstruction coefficient of the blood flow cavity from the left ventricular cavity to the outflow tract segment and the cardiac obstruction coefficient of the outflow tract to the ascending aorta segment;

[0009] The patient's obstruction status is assessed based on the aforementioned cardiac obstruction coefficient.

[0010] Furthermore, the method of determining the relationship between cardiac output and outflow tract pressure difference using Bernoulli's equation includes:

[0011] By replacing the outflow velocity in the Bernoulli equation with the cardiac output, the relational equation is obtained.

[0012] Furthermore, by substituting the cardiac output into the outflow velocity in the Bernoulli equation, a relational equation is obtained, including:

[0013] Since the systolic phase occupies one-third of the entire cardiac cycle, assuming that the systolic blood flow is three times the cardiac output, that is... ;

[0014] The equation for calculating pressure difference in color Doppler ultrasound then changes to:

[0015]

[0016] in, This indicates the pressure difference between the left ventricular cavity and the outflow tract. Indicates cardiac output. Indicates the velocity of blood flow out of the circulatory system. Indicates the flow rate during the systolic phase. This indicates the cross-sectional area at the outlet.

[0017] Furthermore, the cardiac obstruction coefficient is calculated based on the aforementioned relationship equation in the following manner:

[0018]

[0019] in, This represents the cardiac obstruction coefficient.

[0020] Furthermore, assessing the patient's obstruction status based on the aforementioned cardiac obstruction coefficient includes:

[0021] When the cardiac obstruction coefficient is 0, it means that the local measured pressure difference is ignored and is considered to be 0.

[0022] When the cardiac obstruction coefficient is infinite, it means that the blood flow chamber is completely blocked and the cardiac output is 0.

[0023] Furthermore, the higher the cardiac obstruction coefficient, the more severe the obstruction in the patient.

[0024] This application provides a device for quantitatively assessing left ventricular outflow tract obstruction and aortic stenosis, comprising:

[0025] The acquisition module is used to acquire the outflow channel pressure difference and cardiac output, and to determine the relationship equation between the cardiac output and the outflow channel pressure difference using Bernoulli's equation.

[0026] The calculation module is used to calculate the cardiac obstruction coefficient based on the relationship equation; the cardiac obstruction coefficient includes the cardiac obstruction coefficient of the blood flow cavity from the left ventricular cavity to the outflow tract segment and the cardiac obstruction coefficient of the outflow tract to the ascending aorta segment;

[0027] An assessment module is used to assess a patient's obstruction status based on the cardiac obstruction coefficient.

[0028] This application provides a computer device, including a memory and a processor. The memory stores a computer program, which, when executed by the processor, causes the processor to perform the steps of any of the above-described methods for quantitatively assessing left ventricular outflow tract obstruction and aortic stenosis.

[0029] The beneficial effects that can be achieved by adopting the above technical solution in this invention include:

[0030] This invention provides a method and apparatus for quantitatively assessing left ventricular outflow tract obstruction and aortic stenosis. The cardiac obstruction coefficient based on color Doppler ultrasound provided in this application is mainly determined by the morphology of the patient's blood flow cavity and is not affected by cardiac output. Compared with the prior art, the technical solution provided in this application can more accurately describe the patient's obstruction status, helping doctors make more accurate judgments in clinical practice. In addition, the cardiac obstruction coefficient based on color Doppler ultrasound provided in this application is based on the more clinically accessible ultrasound measurement of differential pressure and the patient's cardiac output, which may be easier to promote in clinical use and will not significantly increase the burden on patients. Attached Figure Description

[0031] To more clearly illustrate the technical solutions in the embodiments of the present invention or the prior art, the drawings used in the description of the embodiments or the prior art will be briefly introduced below. Obviously, the drawings described below are only some embodiments of the present invention. For those skilled in the art, other drawings can be obtained based on these drawings without creative effort.

[0032] Figure 1 This is a schematic diagram illustrating the steps of the method for quantitatively assessing left ventricular outflow tract obstruction and aortic stenosis according to the present invention;

[0033] Figure 2 A three-dimensional model of a patient with myocardial infarction provided by the present invention;

[0034] Figure 3 A simplified hemodynamic diagram of a patient with cardiac obstruction provided by this invention;

[0035] Figure 4 This is a schematic diagram of the device for quantitatively assessing left ventricular outflow tract obstruction and aortic stenosis according to the present invention.

[0036] Figure 5 This is a schematic diagram of the computer device involved in the method for quantitatively assessing left ventricular outflow tract obstruction and aortic stenosis according to the present invention. Detailed Implementation

[0037] To make the objectives, technical solutions, and advantages of this invention clearer, the technical solutions of this invention will be described in detail below. Obviously, the described embodiments are merely some embodiments of this invention, and not all embodiments. Based on the embodiments of this invention, all other implementation methods obtained by those skilled in the art without creative effort are within the scope of protection of this invention.

[0038] Left ventricular outflow tract obstruction usually refers to a condition in patients with hypertrophic obstructive heart disease where blood flow during the systolic ejection phase is blocked by the hypertrophic interventricular septum myocardium and the SAM (systolic anterior motion) of the mitral valve, preventing effective pumping of blood out of the heart. Aortic stenosis may also obstruct cardiac ejection.

[0039] The following describes, with reference to the accompanying drawings, a specific method and apparatus for quantitatively assessing left ventricular outflow tract obstruction and aortic stenosis provided in the embodiments of this application.

[0040] like Figure 1 As shown in the embodiments of this application, the method for quantitatively assessing left ventricular outflow tract obstruction and aortic stenosis includes:

[0041] S101, Obtain the outflow tract pressure difference and cardiac output, and use Bernoulli's equation to determine the relationship equation between the cardiac output and the outflow tract pressure difference;

[0042] like Figure 2 As shown, this application constructs a three-dimensional model of the left ventricular cavity to aortic segment of a patient with hypertrophic heart disease, and then draws a simplified hemodynamic diagram based on the three-dimensional model. The simplified hemodynamic diagram is shown below. Figure 3 As shown. The hemodynamic parameters include systolic blood flow. Increase aortic pressure Outflow pressure Left ventricular pressure Increase aortic blood flow velocity Outflow tract blood flow velocity Left ventricular blood flow velocity Pressure difference between the left ventricular cavity and the outflow tract Pressure drop from the left ventricular cavity to the aortic segment Aortic valve AV and mitral valve MV.

[0043] First, assuming that the blood flow velocity in the left ventricular cavity is much smaller than that in the outflow tract, the Bernoulli equation is simplified without considering the effect of gravitational acceleration, resulting in the simplified Bernoulli equation; the simplified Bernoulli equation represents the relationship between the pressure difference from the left ventricular cavity to the outflow tract and the outflow tract blood flow velocity.

[0044] The cardiac output obtained by substituting the outflow tract blood flow velocity with the cardiac output obtained by the Bernoulli simplified equation is used to obtain the relational equation; the relational equation represents the relationship between the pressure difference from the left ventricular cavity to the outflow tract segment and the cardiac output.

[0045] Specifically, in this application, based on Bernoulli's equation for ideal fluids, the following is provided:

[0046] (1)

[0047] in, Represents blood density, g represents gravitational acceleration. and These represent the heights of the left ventricular cavity and the outflow tract, respectively. Formula (1) applies when blood is considered an ideal fluid, and energy loss due to obstruction of the blood flow cavity is not considered. Typically, in patients with outflow tract obstruction and aortic stenosis, there is often an increase in blood flow velocity at the site of local stenosis. Therefore, it is assumed that the blood flow velocity in the left ventricular cavity... Given the outflow tract blood flow velocity and without considering the effect of gravitational acceleration, equation (1) can be simplified to the equation used in color Doppler ultrasound.

[0048] (2)

[0049] Formula (2) is the formula for calculating the pressure difference based on blood flow velocity, which is widely used in color Doppler ultrasound. According to formula (2), the pressure difference measured by color Doppler ultrasound in clinical practice is entirely determined by the blood flow velocity at the outflow tract and aortic valve, and has a quadratic relationship with the local blood flow velocity.

[0050] In some embodiments, determining the relationship between cardiac output and outflow tract pressure differential using Bernoulli's equation includes:

[0051] By replacing the outflow velocity in the Bernoulli equation with the cardiac output, the relational equation is obtained.

[0052] As a specific implementation method, replacing the outflow tract blood flow velocity in the Bernoulli equation with the cardiac output, a relational equation is obtained, including:

[0053] Since the systolic phase occupies one-third of the entire cardiac cycle, assuming that the systolic blood flow is three times the cardiac output, that is... ;

[0054] Specifically, based on clinical observations and related medical research, local obstruction is greatly affected by load conditions and myocardial contractility, exhibiting characteristics of dynamic obstruction. Based on formula (2), further derivation yields the following equation for calculating pressure difference in color Doppler ultrasound:

[0055] (3)

[0056] in, Indicates cardiac output. Indicates the flow rate during the systolic phase. This indicates the cross-sectional area at the outlet.

[0057] Formula (3) shows that the pressure difference measured by ultrasound is mainly directly related to two physiological parameters of the patient: the cross-sectional area of ​​the outflow tract and the cardiac output. The conclusions obtained by formula (3) are also consistent with clinical observations and related medical research. When the morphology of the blood flow cavity at the outflow tract does not change ( (If the outflow tract obstruction remains constant), from a morphological perspective, changes in cardiac output directly affect the pressure gradient measured by color Doppler ultrasound. The ultrasound-measured pressure gradient has a quadratic relationship with the patient's cardiac output. Clinically, we observe that some patients with severe obstruction show a significant decrease in cardiac output, and the pressure gradient measured by ultrasound will be correspondingly smaller, thus underestimating the severity of the obstruction. The differences in assessment are even greater for patients with significant systolic mitral regurgitation. Similarly, for patients with abnormally thickened papillary muscles and significant left ventricular wall hypertrophy, insufficient left ventricular volume also leads to a decrease in cardiac output, further resulting in a smaller measured outflow tract pressure gradient. Another type of patient has mid-segment left ventricular obstruction, where blood flow near the apex cannot be effectively pumped out of the heart during systole, also causing a decrease in cardiac output and a smaller measured pressure gradient. Some of these situations are quite severe, and judging the severity of a patient's blood flow cavity obstruction and aortic stenosis solely based on the pressure gradient measured by color Doppler ultrasound may underestimate the severity of the condition, potentially leading to irreversible consequences.

[0058] S102, Calculate the cardiac obstruction coefficient based on the relationship equation; the cardiac obstruction coefficient includes the cardiac obstruction coefficient of the blood flow cavity from the left ventricular cavity to the outflow tract segment and the cardiac obstruction coefficient of the outflow tract to the ascending aorta segment;

[0059] Based on formula (3), the cardiac obstruction coefficient based on color Doppler ultrasound is calculated to eliminate the influence of cardiac output fluctuations on the pressure difference measured by ultrasound. Specifically:

[0060] (4)

[0061] in, This is the cardiac obstruction coefficient calculated based on color Doppler ultrasound. Formula (4) shows how to eliminate the influence of cardiac output on the pressure difference measured by ultrasound, and mainly consider the influence of the outflow tract cross-sectional area. Theoretically, the cardiac obstruction coefficient based on color Doppler ultrasound is a parameter determined by the morphology of the blood flow cavity at the obstruction location, which can be used to quantitatively describe the obstruction at the heart. It can be directly calculated from two common clinical parameters: the pressure difference at the outflow tract measured by ultrasound and cardiac output. The value of the cardiac obstruction coefficient based on color Doppler ultrasound is between 0 and infinity.

[0062] S103, assess the patient's obstruction status based on the cardiac obstruction coefficient.

[0063] This indicates that the local pressure difference is very small and can be ignored. ). This indicates that the blood flow chamber is completely blocked, and the cardiac output is 0 (CO=0). The cardiac obstruction coefficient can be used for clinical quantitative analysis of local obstruction.

[0064] As a specific implementation method, suppose a patient's ultrasound measurement is performed clinically. , The calculation of the cardiac obstruction coefficient based on ultrasound is as follows:

[0065]

[0066] The higher the cardiac obstruction coefficient, the more severe the obstruction. If we consider... As a baseline, given that both patients have the same cardiac output (5 mL / min), a higher one... This indicates that the patient's obstruction is more severe. On the other hand, when two patients... Patients with the same cardiac output (25 mmHg) but lower cardiac output This also indicates a more severe obstruction. It is important to emphasize that when using the cardiac obstruction coefficient, it is essential to specify which segment of the blood flow chamber it pertains to, for example... This represents the cardiac obstruction coefficient of the blood flow cavity from the left ventricular cavity to the outflow tract segment, while The cardiac obstruction coefficient represents the distance from the outflow tract to the ascending aorta, and it can be used to quantitatively describe the severity of aortic stenosis.

[0067] The cardiac obstruction coefficient based on color Doppler ultrasound in this application is primarily determined by the morphology of the patient's blood flow cavity and is not affected by cardiac output. Compared to traditional clinical measurement parameters such as the pressure difference calculated based on the maximum outflow velocity and pressure gradient, it can more accurately describe the patient's obstruction status, which helps doctors make more accurate judgments in clinical practice. Compared to the cardiac obstruction coefficient derived solely from fluid dynamics formulas (calculated using the pressure drop from the left ventricular cavity to the ascending aorta), the cardiac obstruction coefficient based on color Doppler ultrasound, which is based on the more readily available ultrasound measurement pressure gradient and the patient's cardiac output, may be easier to promote in clinical use and will not significantly increase the burden on patients.

[0068] like Figure 4 As shown, this application provides a device for quantitatively assessing left ventricular outflow tract obstruction and aortic stenosis, comprising:

[0069] The acquisition module 201 is used to acquire the pressure difference and cardiac output of the outflow channel segment, and to determine the relationship equation between the cardiac output and the pressure difference of the outflow channel segment using the Bernoulli equation.

[0070] Calculation module 202 is used to calculate the cardiac obstruction coefficient based on the relational equation; the cardiac obstruction coefficient includes the cardiac obstruction coefficient of the blood flow cavity from the left ventricular cavity to the outflow tract segment and the cardiac obstruction coefficient of the outflow tract to the ascending aorta segment;

[0071] The assessment module 203 is used to assess the patient's obstruction status based on the cardiac obstruction coefficient.

[0072] The working principle of the device for quantitatively assessing left ventricular outflow tract obstruction and aortic stenosis provided in this application is as follows: the acquisition module 201 acquires the outflow tract segment pressure gradient and cardiac output, and uses Bernoulli's equation to determine the relationship equation between the cardiac output and the outflow tract segment pressure gradient; the calculation module 202 calculates the cardiac obstruction coefficient based on the relationship equation; the cardiac obstruction coefficient includes the cardiac obstruction coefficient from the left ventricular cavity to the outflow tract segment blood flow cavity and the cardiac obstruction coefficient from the outflow tract to the ascending aorta segment; the assessment module 203 assesses the patient's obstruction status based on the cardiac obstruction coefficient.

[0073] This application provides a computer device, including: a memory 1 and a processor 2, and may further include a network interface 3. The memory stores a computer program and may include non-persistent memory in the form of computer-readable media, random access memory (RAM), and / or non-volatile memory, such as read-only memory (ROM) or flash RAM. The computer device stores an operating system 4, and the memory is an example of a computer-readable medium. When the computer program is executed by the processor, it causes the processor to perform a method for quantitatively assessing left ventricular outflow tract obstruction and aortic stenosis. Figure 5The structure shown is merely a block diagram of a portion of the structure related to the present application and does not constitute a limitation on the computer device to which the present application is applied. Specific computer devices may include more or fewer components than those shown in the figure, or combine certain components, or have different component arrangements.

[0074] In one embodiment, the method for quantitatively assessing left ventricular outflow tract obstruction and aortic stenosis provided in this application can be implemented as a computer program, which can be implemented in the form of, for example, Figure 5 It runs on the computer device shown.

[0075] In some embodiments, when the computer program is executed by the processor, the processor performs the following steps: acquiring the outflow tract pressure gradient and cardiac output; determining the relationship between the cardiac output and the outflow tract pressure gradient using Bernoulli's equation; calculating the cardiac obstruction coefficient based on the relationship equation; the cardiac obstruction coefficient including the cardiac obstruction coefficient from the left ventricular cavity to the outflow tract blood flow cavity and the cardiac obstruction coefficient from the outflow tract to the ascending aorta; and assessing the patient's obstruction status based on the cardiac obstruction coefficient.

[0076] This application also provides a computer storage medium, examples of which include, but are not limited to, phase-change memory (PRAM), static random access memory (SRAM), dynamic random access memory (DRAM), other types of random access memory (RAM), read-only memory (ROM), electrically erasable programmable read-only memory (EEPROM), flash memory or other memory technologies, CD-ROM, digital optical disc (DVD) or other optical storage, magnetic tape storage or other magnetic storage devices, or any other non-transfer medium, which can be used to store information that can be accessed by a computing device.

[0077] In some embodiments, the present invention also proposes a computer-readable storage medium storing a computer program that, when executed by a processor, acquires the outflow tract pressure gradient and cardiac output, determines the relationship between the cardiac output and the outflow tract pressure gradient using Bernoulli's equation, calculates a cardiac obstruction coefficient based on the relationship equation, the cardiac obstruction coefficient including the cardiac obstruction coefficient from the left ventricular cavity to the outflow tract blood flow cavity and the cardiac obstruction coefficient from the outflow tract to the ascending aorta, and assesses the patient's obstruction status based on the cardiac obstruction coefficient.

[0078] In summary, this invention provides a method and apparatus for quantitatively assessing left ventricular outflow tract obstruction and aortic stenosis. The method includes acquiring the outflow tract pressure gradient and cardiac output; determining the relationship between cardiac output and outflow tract pressure gradient using Bernoulli's equation; calculating a cardiac obstruction coefficient based on the equation; the cardiac obstruction coefficient includes the cardiac obstruction coefficient from the left ventricular cavity to the outflow tract segment and the cardiac obstruction coefficient from the outflow tract to the ascending aorta; and assessing the patient's obstruction status based on the cardiac obstruction coefficient. The cardiac obstruction coefficient calculated by this invention is primarily determined by the morphology of the patient's blood flow cavity and is not affected by cardiac output, thus providing a more accurate description of the patient's obstruction status. This helps physicians make more accurate clinical judgments.

[0079] It is understood that the method embodiments provided above correspond to the device embodiments described above, and the specific details can be referred to each other, which will not be repeated here.

[0080] Those skilled in the art will understand that embodiments of this application can be provided as methods, systems, or computer program products. Therefore, this application can take the form of a completely hardware embodiment, a completely software embodiment, or an embodiment combining software and hardware aspects. Furthermore, this application can take the form of a computer program product implemented on one or more computer-usable storage media (including, but not limited to, disk storage and optical storage) containing computer-usable program code.

[0081] This application is described with reference to flowchart illustrations and / or block diagrams of methods, apparatus (systems), and computer program products according to embodiments of this application. It will be understood that each block of the flowchart illustrations and / or block diagrams, and combinations of blocks in the flowchart illustrations and / or block diagrams, can be implemented by computer program instructions. These computer program instructions can be provided to a processor of a general-purpose computer, special-purpose computer, embedded processor, or other programmable data processing apparatus to produce a machine, such that the instructions, which execute via the processor of the computer or other programmable data processing apparatus, generate instructions for implementing the flowchart... Figure 1 One or more processes and / or boxes Figure 1 A device that provides the functions specified in one or more boxes.

[0082] These computer program instructions may also be stored in a computer-readable storage medium that can direct a computer or other programmable data processing device to operate in a particular manner, such that the instructions stored in the computer-readable storage medium produce an article of manufacture including instruction methods implemented in a process. Figure 1 One or more processes and / or boxes Figure 1 The function specified in one or more boxes.

[0083] These computer program instructions may also be loaded onto a computer or other programmable data processing equipment to cause a series of operational steps to be performed on the computer or other programmable equipment to produce a computer-implemented process, thereby providing instructions that execute on the computer or other programmable equipment for implementing the process. Figure 1 One or more processes and / or boxes Figure 1 The steps of the function specified in one or more boxes.

[0084] The above description is merely a specific embodiment of the present invention, but the scope of protection of the present invention is not limited thereto. Any variations or substitutions that can be easily conceived by those skilled in the art within the technical scope disclosed in the present invention should be included within the scope of protection of the present invention. Therefore, the scope of protection of the present invention should be determined by the scope of the claims.

Claims

1. A device for quantitatively assessing left ventricular outflow tract obstruction and aortic stenosis, characterized in that, include: The acquisition module is used to acquire the outflow tract pressure difference and cardiac output, and replace the outflow tract blood flow velocity in Bernoulli's equation with the cardiac output to obtain the relationship equation; Specifically, this is used based on the fact that the systolic phase occupies one-third of the entire cardiac cycle, assuming that the systolic blood flow is three times the cardiac output. ; The equation for calculating pressure difference in color Doppler ultrasound then changes to: in, This indicates the pressure difference between the left ventricular cavity and the outflow tract. Indicates cardiac output. Indicates the velocity of blood flow out of the circulatory system. Indicates the flow rate during the systolic phase. This indicates the cross-sectional area at the outlet. The calculation module is used to calculate the cardiac obstruction coefficient based on the aforementioned relational equation; the cardiac obstruction coefficient includes the cardiac obstruction coefficient from the left ventricular cavity to the outflow tract segment and the cardiac obstruction coefficient from the outflow tract to the ascending aorta segment; wherein, the cardiac obstruction coefficient is calculated based on the aforementioned relational equation in the following manner. in, Indicates the cardiac obstruction coefficient; An assessment module is used to assess a patient's obstruction status based on the cardiac obstruction coefficient.

2. The apparatus according to claim 1, characterized in that, The evaluation module is specifically used for: When the cardiac obstruction coefficient is 0, it means that the local measured pressure difference is ignored and is considered to be 0. When the cardiac obstruction coefficient is infinite, it means that the blood flow chamber is completely blocked and the cardiac output is 0.

3. The apparatus according to claim 1, characterized in that, The higher the cardiac obstruction coefficient, the more severe the obstruction in the patient.

4. A computer device, characterized in that, include: A memory and a processor, the memory storing a computer program that, when executed by the processor, causes the processor to perform a method for quantitatively assessing left ventricular outflow tract obstruction and aortic stenosis: By obtaining the outflow tract pressure gradient and cardiac output, and substituting the outflow tract blood flow velocity in Bernoulli's equation with the cardiac output, a relational equation is obtained, including: assuming that the systolic phase occupies one-third of the entire cardiac cycle, the systolic flow rate is assumed to be three times the cardiac output, i.e. ; The equation for calculating pressure difference in color Doppler ultrasound then changes to: in, This indicates the pressure difference between the left ventricular cavity and the outflow tract. Indicates cardiac output. Indicates the velocity of blood flow in the outflow tract. Indicates the flow rate during the systolic phase. This indicates the cross-sectional area at the outlet. The cardiac obstruction coefficient is calculated based on the aforementioned relationship equation; the cardiac obstruction coefficient includes the cardiac obstruction coefficient from the left ventricular cavity to the outflow tract segment and the cardiac obstruction coefficient from the outflow tract to the ascending aorta segment; wherein, the cardiac obstruction coefficient is calculated based on the aforementioned relationship equation using the following method. in, Indicates the cardiac obstruction coefficient; The patient's obstruction status is assessed based on the aforementioned cardiac obstruction coefficient.

5. The computer device according to claim 4, characterized in that, The method for quantitatively assessing left ventricular outflow tract obstruction and aortic stenosis includes: when the cardiac obstruction coefficient is 0, it indicates that the local measurement pressure difference is ignored as 0; When the cardiac obstruction coefficient is infinite, it means that the blood flow chamber is completely blocked and the cardiac output is 0.

6. The computer device according to claim 4, characterized in that, The method for quantitatively assessing left ventricular outflow tract obstruction and aortic stenosis includes: the larger the cardiac obstruction coefficient, the more severe the patient's obstruction.

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