Method for determining region of interest in ultrasonic image, and ultrasonic imaging device

Abstract

Embodiments of the present application provide a method for determining a region of interest in an ultrasound image and an ultrasound imaging device. The method comprises: acquiring a uterine ultrasound image and displaying the uterine ultrasound image via a display interface; determining first feature points of the endometrium in the uterine ultrasound image, the first feature points comprising a feature point located at the cervix and a feature point located at the fundus; automatically connecting the first feature points comprising the feature points of the cervix and the fundus according to the direction of the endometrium to form an endometrial boundary line of the endometrium; and determining the region in the uterine ultrasound image between at least the endometrial boundary lines as the region of interest. This application can improve the accuracy and efficiency of determining a region of interest that aligns with the endometrial / junctional zone morphology.

Description

Technical Field

[0001] The present application relates to the technical field of medical equipment, and in particular to a method for determining a region of interest in an ultrasound image and an ultrasound imaging device. Background Art

[0002] Endometrial receptivity refers to the state of the endometrium that allows the blastocyst to locate, adhere, and invade, leading to changes in the endometrial stroma and ultimately leading to embryo implantation. This refers to the ability of the endometrium to accept a fertilized egg. Accurately assessing endometrial receptivity is clinically significant in selecting implantation timing and assessing pregnancy rates, and is a crucial component of today's reproductive assessment system.

[0003] Endometrial peristaltic waves refer to mechanical waves generated by the contraction of the synaptic zone at the junction of the myometrium and endometrium, driving endometrial peristalsis. The frequency, direction, and intensity of these peristaltic waves vary with the menstrual cycle, assisting sperm transport and embryo implantation. They are important indicators of endometrial receptivity. Uterine peristalsis patterns can also be affected by uterine diseases, so studying peristaltic waves has the potential to aid in the diagnosis of uterine pathologies.

[0004] Currently, there are technical solutions for qualitative and quantitative analysis of endometrial peristaltic waves. However, since the movements inside the uterus (outside the endometrium) are complex and disordered, and may also be affected by intestinal peristalsis and breathing, etc., it may cause visual interference to the observation and display of endometrial or fusion zone peristalsis. Therefore, it is necessary to eliminate motion interference in non-areas of interest and lock the observation range to only the endometrium or fusion zone area. Summary of the Invention

[0005] The present application provides a method for determining a region of interest in an ultrasound image and an ultrasound imaging device, aiming to improve the accuracy and efficiency of determining a region of interest that is consistent with the endometrial / junctional zone morphology.

[0006] In a first aspect, an embodiment of the present application provides a method for determining a region of interest in an ultrasound image, comprising:

[0007] Acquiring a uterine ultrasound image, and displaying the uterine ultrasound image through a display interface of a display;

[0008] Determine first feature points of the endometrium in the uterine ultrasound image, where the first feature points include feature points located at the cervix and feature points located at the fundus of the uterus;

[0009] automatically connecting the first feature points including the feature points of the cervix and the feature points of the uterine fundus according to the direction of the endometrium to form an endometrial boundary line of the endometrium;

[0010] At least a region between the endometrial boundary lines in the uterine ultrasound image is determined as the region of interest.

[0011] In a second aspect, an embodiment of the present application provides a method for determining a region of interest in an ultrasound image, comprising:

[0012] Acquiring a uterine ultrasound image, and displaying the uterine ultrasound image through a display interface of a display;

[0013] Determine first feature points of the endometrium in the uterine ultrasound image, where the first feature points include feature points located at the cervix and feature points located at the fundus of the uterus;

[0014] automatically connecting the first feature points one by one from a feature point at one end of the endometrium to a feature point at the other end of the endometrium according to the direction of the endometrium to form an endometrial boundary line of the endometrium, wherein one end of the endometrium is the cervix and the other end of the endometrium is the fundus, or one end of the endometrium is the fundus and the other end of the endometrium is the cervix;

[0015] At least a region between the endometrial boundary lines in the uterine ultrasound image is determined as the region of interest.

[0016] In a third aspect, an embodiment of the present application provides a method for determining a region of interest in an ultrasound image, comprising:

[0017] Acquiring a uterine ultrasound image, and displaying the uterine ultrasound image through a display interface of a display;

[0018] Determine first feature points of the endometrium in the uterine ultrasound image, where the first feature points include feature points located at the cervix and feature points located at the fundus of the uterus;

[0019] According to the direction of the endometrium, the characteristic points of the first side of the endometrium are automatically connected one by one from the characteristic points at one end to the characteristic points at the other end to form a boundary line of the first side of the endometrium;

[0020] According to the direction of the endometrium, the characteristic points of the second side of the endometrium are automatically connected one by one from the characteristic points at the other end to the characteristic points at one end to form a boundary line of the second side of the endometrium;

[0021] Wherein, the first endometrium is the anterior uterine membrane, and the second endometrium is the posterior uterine membrane, or the first endometrium is the posterior uterine membrane, and the second endometrium is the anterior uterine membrane;

[0022] At least a region between the first endometrial boundary line and the second endometrial boundary line in the uterine ultrasound image is determined as the region of interest.

[0023] In a fourth aspect, an embodiment of the present application provides a method for determining a region of interest in an ultrasound image, comprising:

[0024] Acquiring a uterine ultrasound image, and displaying the uterine ultrasound image through a display interface of a display;

[0025] determining second feature points in the uterine cavity of the endometrium in the uterine ultrasound image, wherein the second feature points include feature points located at the cervix and feature points located at the fundus of the uterus;

[0026] automatically connecting the second feature points including the feature points of the cervix and the feature points of the uterine fundus according to the direction of the endometrium to form a uterine cavity line of the endometrium;

[0027] generating an anterior membrane boundary line and a posterior membrane boundary line based on the uterine cavity line;

[0028] At least a region between the anterior membrane boundary line and the posterior membrane boundary line in the uterine ultrasound image is determined as the region of interest.

[0029] In a fifth aspect, an embodiment of the present application provides a method for determining a region of interest in an ultrasound image, comprising:

[0030] Acquiring a uterine ultrasound image, and displaying the uterine ultrasound image through a display interface of a display;

[0031] determining second feature points in the uterine cavity of the endometrium in the uterine ultrasound image, wherein the second feature points include feature points located at the cervix and feature points located at the fundus of the uterus;

[0032] automatically connecting the second feature points including the feature points of the cervix and the feature points of the uterine fundus according to the direction of the endometrium to form a uterine cavity line of the endometrium;

[0033] generating an anterior membrane boundary line and / or a posterior membrane boundary line based on the uterine cavity line;

[0034] Determine in the uterine ultrasound image that the region between at least any two of the anterior membrane boundary line, the posterior membrane boundary line, and the uterine cavity line is the region of interest.

[0035] In a sixth aspect, an embodiment of the present application provides a method for determining a region of interest in an ultrasound image, comprising:

[0036] Acquiring a uterine ultrasound image, and displaying the uterine ultrasound image through a display interface of a display;

[0037] Determine first feature points of the endometrium in the uterine ultrasound image, where the first feature points include feature points located at the cervix and feature points located at the fundus of the uterus;

[0038] automatically connecting the first feature points including the feature points of the cervix and the feature points of the uterine fundus according to the direction of the endometrium to form an endometrial boundary line of the endometrium;

[0039] generating a uterine cavity line based on an endometrial boundary line of the endometrium;

[0040] At least a region between the endometrial boundary line and the uterine cavity line in the uterine ultrasound image is determined as the region of interest.

[0041] In a seventh aspect, an embodiment of the present application provides a method for determining a region of interest in an ultrasound image, comprising:

[0042] Acquiring a uterine ultrasound image, and displaying the uterine ultrasound image through a display interface of a display;

[0043] Determine first feature points of a first side of the endometrium in the uterine ultrasound image, wherein the first feature points include feature points located at the cervix and feature points located at the fundus of the uterus; wherein the first side of the endometrium includes anterior uterine membrane or posterior uterine membrane of the endometrium;

[0044] automatically connecting the first feature points including the feature points of the cervix and the feature points of the fundus according to the direction of the endometrium to form a first boundary line of the endometrium on the first side;

[0045] generating a second boundary line based on the first boundary line at a position away from the first endometrium and close to the myometrium;

[0046] At least a region between the first boundary line and the second boundary line in the uterine ultrasound image is determined as the region of interest.

[0047] In an eighth aspect, an embodiment of the present application provides a method for determining a region of interest in an ultrasound image, comprising:

[0048] Acquiring a uterine ultrasound image, and displaying the uterine ultrasound image through a display interface of a display;

[0049] determining a third feature point of the endometrium in the uterine ultrasound image, wherein the third feature point includes a feature point located at the cervix and a feature point located at the fundus of the uterus;

[0050] According to the direction of the endometrium, the third characteristic points are automatically connected one by one along the shortest path to form an endometrial boundary line of the endometrium;

[0051] At least a region between the endometrial boundary lines in the uterine ultrasound image is determined as the region of interest.

[0052] In a ninth aspect, an embodiment of the present application provides an ultrasonic imaging device, comprising:

[0053] Probe;

[0054] a transmitting circuit, wherein the transmitting circuit excites the probe to transmit ultrasonic waves toward the uterus;

[0055] a receiving circuit, wherein the receiving circuit controls the probe to receive the ultrasonic echo to obtain an ultrasonic echo signal;

[0056] Display, providing a display interface;

[0057] The ultrasonic imaging device processes the ultrasonic echo signal to obtain a uterine ultrasonic image; and performs the steps of the aforementioned method for determining a region of interest in an ultrasonic image to determine a region of interest in the uterine ultrasonic image;

[0058] The ultrasonic imaging device is further used to extract and process the ultrasonic echo signal of the region of interest to obtain the peristaltic motion parameters of the region of interest; and to display a graph showing the peristaltic motion parameters of the region of interest changing over time through the display interface of the display.

[0059] In a ninth aspect, an embodiment of the present application provides a computer-readable storage medium, wherein the computer-readable storage medium stores a computer program, and when the computer program is executed by a processor, the processor implements the above-mentioned method.

[0060] An embodiment of the present application provides a method for determining a region of interest in an ultrasound image and an ultrasound imaging device, which forms an endometrial boundary line of the endometrium by determining a first feature point of the endometrium in a uterine ultrasound image and automatically connecting the first feature point according to the direction of the endometrium. Therefore, the boundaries of the region of interest on both sides of the endometrium can be determined based on the determined endometrial boundary line; at the same time, the first feature point includes a feature point located at the cervix and a feature point located at the fundus, which can define the endpoints of the endometrial boundary line at the cervix and the fundus; the region of interest in the uterine ultrasound image can be more accurately identified, and interference with the observation and analysis of peristalsis caused by movement outside the region of interest can be eliminated, so that the observation range can be better locked to only the endometrium or the junction zone area.

[0061] It should be understood that the above general description and the following detailed description are merely exemplary and explanatory and do not limit the disclosure of the embodiments of the present application. BRIEF DESCRIPTION OF THE DRAWINGS

[0062] In order to more clearly illustrate the technical solutions of the embodiments of the present application, the following briefly introduces the drawings required for use in the description of the embodiments. Obviously, the drawings described below are some embodiments of the present application. For ordinary technicians in this field, other drawings can be obtained based on these drawings without any creative work.

[0063] Figure 1 1 is a flow chart of a method for determining a region of interest in an ultrasound image provided by an embodiment of the present application;

[0064] Figure 2 is a schematic block diagram of an ultrasonic imaging device in one embodiment;

[0065] Figure 3 is a schematic diagram of peristaltic wave detection in one embodiment;

[0066] Figures 4 to 8 is a schematic diagram of determining a region of interest in different implementations;

[0067] Figure 9 is a flowchart of a method for determining a region of interest in an ultrasound image provided by another embodiment of the present application;

[0068] Figure 10 1 is a flow chart of a method for determining a region of interest in an ultrasound image provided by another embodiment of the present application;

[0069] Figure 11 1 is a flow chart of a method for determining a region of interest in an ultrasound image provided by yet another embodiment of the present application;

[0070] Figures 12 to 15 is a schematic diagram of determining a region of interest in different implementations;

[0071] Figure 16 1 is a flow chart of a method for determining a region of interest in an ultrasound image provided by yet another embodiment of the present application;

[0072] Figure 17 FIG. 1 is a schematic diagram of determining a region of interest in one embodiment. DETAILED DESCRIPTION

[0073] The following will be combined with the drawings in the embodiments of this application to clearly and completely describe the technical solutions in the embodiments of this application. Obviously, the embodiments described are part of the embodiments of this application, not all of them. Based on the embodiments in this application, all other embodiments obtained by ordinary technicians in this field without making creative efforts are within the scope of protection of this application.

[0074] The flowcharts shown in the accompanying drawings are for illustrative purposes only and do not necessarily include all contents and operations / steps, nor must they be executed in the order described. For example, some operations / steps may be decomposed, combined, or partially merged, so the actual execution order may vary depending on the actual situation.

[0075] The following describes some embodiments of the present application in detail with reference to the accompanying drawings. In the absence of conflict, the following embodiments and features therein may be combined with each other.

[0076] See also Figure 1 , Figure 1 This is a flow chart of a method for determining a region of interest in an ultrasound image, provided in an embodiment of the present application. The method can be applied to a device for determining a region of interest in an ultrasound image, for determining a region of interest of the endometrium or fusion zone in an ultrasound image; for example, the method can be applied to an ultrasound imaging device, other terminal devices, or a server.

[0077] Figure 2 1 is a schematic block diagram of the structure of an ultrasonic imaging device provided in an embodiment of the present application. The ultrasonic imaging device 10 may include a probe 100, a transmitting circuit 101, a transmit / receive selection switch 102, a receiving circuit 103, a beamforming circuit 104, a processor 105, and a display 106. The transmitting circuit 101 can stimulate the probe 100 to transmit ultrasonic waves toward the target tissue; the receiving circuit 103 can receive ultrasonic echoes returned from the target tissue through the probe 100, thereby obtaining ultrasonic echo signals / data; the ultrasonic echo signals / data are subjected to beamforming processing by the beamforming circuit 104 and then sent to the processor 105. The processor 105 can process the ultrasonic echo signals / data to obtain ultrasonic images or other data of the target tissue. The ultrasonic images obtained by the processor 105 can be stored in the memory 107. These ultrasonic images can be displayed on the display 106.

[0078] In some embodiments, by continuously transmitting ultrasound waves to the uterus for a period of time and detecting the ultrasound echoes, peristaltic motion parameters such as uterine peristaltic displacement or peristaltic velocity at different times can be calculated, thereby objectively evaluating the peristaltic state of the endometrium / coapthalmonic zone. Those skilled in the art will appreciate that ultrasound imaging equipment is also suitable for measuring peristaltic parameters of other tissues, such as the intestines and stomach.

[0079] Specifically, the ultrasound imaging device is configured to process the ultrasound echo signal to obtain a uterine ultrasound image, and to execute the steps of the method for determining a region of interest to determine a region of interest in the uterine ultrasound image. For example, the ultrasound imaging device includes one or more processors 105, which work individually or collectively to execute the steps of the method for determining a region of interest in an ultrasound image.

[0080] The processor 105 is configured to execute a computer program stored in the memory 107 , and when executing the computer program, implement the steps of any method for determining a region of interest in an ultrasound image provided in the embodiments of the present application.

[0081] The ultrasonic imaging device is further used to extract and process the ultrasonic echo signal of the region of interest to obtain the peristaltic motion parameters of the region of interest; and to display a graph showing the peristaltic motion parameters of the region of interest changing over time through the display interface of the display.

[0082] For example, by continuously transmitting ultrasound to a region of interest for a period of time and receiving ultrasound echoes, ultrasound echo signals at various locations in the region of interest can be obtained. The ultrasound echo signals at the locations of interest in the region of interest are extracted, and the ultrasound echo signals at the locations of interest are processed to obtain peristaltic motion parameters at the locations of interest. The location of interest can be the entire region of interest, a portion of the region of interest, multiple portions of the region of interest, a point in the region of interest, or at least one of multiple points in the region of interest. By comparing ultrasound echo signals at different times, the speed or displacement of the peristaltic motion at the location of interest can be calculated. The peristaltic motion parameters can be the speed or displacement of the peristaltic motion, or other motion parameters describing uterine peristalsis calculated from the speed or displacement of the peristaltic motion. The speed or displacement at the location of interest can be calculated from the ultrasound echo signals by block matching or Doppler methods, as well as other motion detection methods based on signal autocorrelation or cross-correlation.

[0083] In some embodiments, as Figure 3 As shown, the scanning control module (processor 105) controls the sequence of ultrasound transmission and echo reception. Two-dimensional image synthesis refers to the processing of conventional ultrasound B-mode imaging, and may also refer to other two-dimensional ultrasound images such as color imaging and PW imaging that can visualize the morphology of the endometrium and / or synaptic zone. A region of interest (ROI) is determined that coincides with the endometrium and / or synaptic zone, and peristaltic waves within the ROI are detected and processed for display.

[0084] like Figure 1 As shown, the method for determining a region of interest in an ultrasound image according to an embodiment of the present application includes steps S110 to S130.

[0085] S110: Acquire a uterine ultrasound image, and display the uterine ultrasound image through a display interface of a display.

[0086] For example, ultrasound waves are transmitted to the uterus and ultrasound echoes are received to obtain ultrasound echo signals, and the ultrasound echo signals are processed to obtain an ultrasound image of the uterus. For example, an ultrasound imaging device uses a transmitting circuit to excite a probe to transmit ultrasound waves toward the uterine region, and a receiving circuit to control the probe to receive the ultrasound echoes, thereby obtaining the ultrasound echo signals. The ultrasound waves can be any type of ultrasound beam, such as at least one of a plane wave, a diverging wave, or a focused wave.

[0087] Exemplarily, the ultrasound image may be any at least one type of ultrasound image, such as a type A ultrasound image, a type B ultrasound image, a type C ultrasound image, etc. The following description will mainly take the type B ultrasound image as an example.

[0088] S120: Determine first feature points of the endometrium in the uterine ultrasound image, where the first feature points include feature points located at the cervix and feature points located at the fundus of the uterus.

[0089] See also Figure 4 The first characteristic points of the endometrium include characteristic points 1 to 6, wherein characteristic point 1 and / or characteristic point 6 are characteristic points located at the fundus of the uterus, and characteristic point 4 and / or characteristic point 5 are characteristic points located at the cervix.

[0090] Specifically, the endometrium includes the anterior uterine membrane and the posterior uterine membrane. Among them, the anterior uterine membrane can be called the first side endometrium, and the posterior uterine membrane can be called the second side endometrium; or, the posterior uterine membrane can be called the first side endometrium, and the anterior uterine membrane can be called the second side endometrium; it can be understood that the first side endometrium can be the anterior uterine membrane or the posterior uterine membrane, and the second side endometrium and the first side endometrium are endometriums on different sides. For ease of explanation, the embodiments of the present application are mainly described by taking the first side endometrium as the anterior uterine membrane and the second side endometrium as the posterior uterine membrane as an example. Figure 4 As shown, the curve connecting feature point 1 to feature point 4 is used to indicate the anterior uterine membrane, and the curve connecting feature point 5 to feature point 6 is used to indicate the posterior uterine membrane.

[0091] Exemplarily, a first feature point of the endometrium in the uterine ultrasound image is determined based on image recognition and / or a feature point selection operation by a user. For example, the first feature point may be manually determined by a user, automatically determined, or manually adjusted by a user after being automatically determined.

[0092] In some embodiments, the method of determining the first feature point of the endometrium in the uterine ultrasound image based on image recognition and determining the region of interest based on the first feature point can be called an automatic method, and the method of determining the first feature point of the endometrium in the uterine ultrasound image based on the user's feature point selection operation and determining the region of interest based on the first feature point can be called a semi-automatic method.

[0093] Exemplarily, the feature points can be automatically identified based on echo signals, B-image grayscale, image edge recognition, or artificial intelligence. For example, a uterine ultrasound image can be identified based on a machine learning model to determine the first feature point of the endometrium in the uterine ultrasound image. The machine learning model is, for example, a deep learning model, but is certainly not limited thereto. It is understandable that when determining the first feature point of the endometrium in the uterine ultrasound image based on image recognition, the uterine ultrasound image can be displayed through the display interface of the display, or the uterine ultrasound image can be not displayed. In some embodiments, the machine learning model can be trained based on the uterine ultrasound image marked with the first feature point, so that the trained machine learning model can identify the uterine ultrasound image and determine the first feature point of the endometrium in the uterine ultrasound image.

[0094] For example, when displaying a uterine ultrasound image on a display interface, a user's feature point selection operation can be detected, such as a click operation on the display interface, to determine the first feature point. After the user clicks and determines the first feature point, the user can click the first feature point again to cancel the determination of the first feature point, or can adjust the position of the first feature point.

[0095] For example, after determining the first feature point based on image recognition, the first feature point is superimposed and displayed when displaying the uterine ultrasound image. The determination of the first feature point can be canceled by clicking the first feature point again, or the position of the first feature point can be adjusted.

[0096] In some embodiments, the first feature point of the endometrium in the uterine ultrasound image includes a feature point located on the first side of the endometrium and a feature point located on the second side of the endometrium. The first side of the endometrium is the anterior uterine membrane and the second side of the endometrium is the posterior uterine membrane, or the first side of the endometrium is the posterior uterine membrane and the second side of the endometrium is the anterior uterine membrane. Figure 4 As shown, the characteristic points located on the first side of the inner membrane include characteristic points 1 to 4, and the characteristic points located on the second side of the inner membrane include characteristic points 5 and 6.

[0097] Illustratively, the feature points located on the first side of the endometrium and the second side of the endometrium each include at least a feature point located on the cervix and a feature point located on the fundus. For example, the user can trace at least two feature points on each side of the endometrium. For example, of the feature points traced on both sides of the endometrium, at least two are located on the fundus and two are located on the cervix.

[0098] Exemplarily, the determining of the first feature point of the endometrium in the uterine ultrasound image based on a feature point selection operation by the user includes: receiving a feature point selection operation from one end of the endometrium to the other end according to the direction of the endometrium, thereby obtaining the first feature point of the endometrium in the uterine ultrasound image. One end of the endometrium is the cervix and the other end of the endometrium is the fundus, or one end of the endometrium is the fundus and the other end of the endometrium is the cervix. For example, a prompt message is outputted through a display interface of a display, and the prompt message may prompt the user to select feature points from one end of the endometrium to the other end according to the direction of the endometrium.

[0099] For example, see Figure 4 The order of determining the first characteristic points can be to mark several first characteristic points along the anterior membrane from the uterine fundus, such as characteristic point 1, to the cervix, such as characteristic points 2 to 4; then, to mark several first characteristic points along the posterior membrane from the cervix, such as characteristic point 5, to the uterine fundus, such as characteristic point 6. Of course, this is not limited to this. For example, the order of determining the first characteristic points can also be the same as Figure 4 The opposite is shown; alternatively, the order of determining the first feature points can be determined by the user independently, for example, the starting first feature point and the ending first feature point can be at the cervix, and the turning first feature point can be at the fundus.

[0100] It should be noted that the number of the first characteristic point of the endometrium in the uterine ultrasound image may or may not be displayed.

[0101] S130: Automatically connect the first feature points including the feature points of the cervix and the feature points of the fundus according to the direction of the endometrium to form an endometrial boundary line of the endometrium.

[0102] In some embodiments, according to the direction of the endometrium, the characteristic points of the cervix of the first endometrium and the characteristic points of the fundus are automatically connected to form a first endometrial boundary line; and according to the direction of the endometrium, the characteristic points of the cervix of the second endometrium and the characteristic points of the fundus are automatically connected to form a second endometrial boundary line. For example, characteristic points 1 to 4 of the anterior uterine membrane are automatically connected to form a first endometrial boundary line, for example, referred to as an anterior endometrial boundary line; and characteristic points 5 to 6 of the posterior endometrium are automatically connected to form a second endometrial boundary line, for example, referred to as a posterior endometrial boundary line.

[0103] For example, when the first feature points are automatically connected, they may be connected in a straight line or in an arc line, but this is not limited thereto. For example, they may also be connected in a broken line.

[0104] Exemplarily, the first feature points including the feature points of the cervix and the feature points of the fundus are automatically connected to form the endometrial boundary line of the endometrium, which can be a broken line segment, a straight line, or a regular or irregular curve, etc., and there is no limitation on this.

[0105] In some embodiments, the first feature points are automatically connected one by one from the feature points at one end of the endometrium to the feature points at the other end of the endometrium according to the direction of the endometrium to form an endometrial boundary line of the endometrium. One end of the endometrium is the cervix and the other end of the endometrium is the fundus, or one end of the endometrium is the fundus and the other end of the endometrium is the cervix. Figure 4 When connecting feature points to form the intimal boundary line, it is possible to connect from feature point 1 to feature point 4 via feature point 2 and feature point 3, and from feature point 5 to feature point 6.

[0106] For example, according to the direction of the endometrium, characteristic points at one end of the first endometrium are automatically connected one by one to characteristic points at the other end, thereby forming a first endometrial boundary line; and according to the direction of the endometrium, characteristic points at one end of the second endometrium are automatically connected one by one to characteristic points at the other end, thereby forming a second endometrial boundary line. For example, when forming the first endometrial boundary line, the connection direction of the characteristic points is the same as or opposite to that when forming the second endometrial boundary line.

[0107] Exemplarily, the method further includes: identifying the region where the endometrium is located, and determining the direction of the endometrium based on the region where the endometrium is located. For example, key structural features in a uterine ultrasound image can be automatically identified through intelligent means such as artificial intelligence and image recognition, thereby automatically determining the region where the endometrium is located in the uterine ultrasound image. The identified region where the endometrium is located can include at least one of various shapes, such as a rectangle, a circle, a sector, a line segment, or a point. For example, the direction of the endometrium can be determined based on the boundary of the region where the endometrium is located.

[0108] Exemplarily, the method further includes: identifying the lateral endometrium of the endometrium, and determining the direction of the endometrium based on the direction of the lateral endometrium. For example, the lateral endometrium of the endometrium, such as the anterior uterine lining and the posterior uterine lining, can be automatically identified using intelligent means such as artificial intelligence and image recognition; and the direction of the endometrium is determined based on the direction of the identified lateral endometrium.

[0109] Illustratively, at least part of the endometrial boundary line formed in step S130 is parallel to the direction of the endometrium, such as the line connecting at least two adjacent first feature points is parallel to the direction of the endometrium.

[0110] In some embodiments, after the endometrial boundary line of the endometrium is formed in step S130, the number and / or position of the first feature points in the uterine ultrasound image can be adjusted based on the user's feature point selection operation, so that the user can adjust the position of the feature points in time to make the subsequently obtained area of ​​interest more accurate.

[0111] In some embodiments, according to the direction of the endometrium, the first feature points are automatically connected one by one along the shortest path to form an endometrial boundary line of the endometrium.

[0112] Exemplarily, a starting point is selected from the first feature points; the starting point is connected one by one in a counterclockwise / clockwise direction and along the shortest path to form the endometrial boundary line of the endometrium.

[0113] For example, the starting point is a feature point located on the cervix or the fundus of the uterus among the third feature points.

[0114] S140: Determine at least the region between the endometrial boundary lines in the uterine ultrasound image as the region of interest.

[0115] In some embodiments, at least the region between the first endometrial border line and the second endometrial border line in the uterine ultrasound image may be determined as the region of interest. Figure 4 , determine that at least the area between the anterior membrane boundary line corresponding to the feature points 1 to 4 and the posterior membrane boundary line corresponding to the feature points 5 to 6 is the region of interest.

[0116] Exemplarily, the two ends of the anterior membrane boundary line and the two ends of the posterior membrane boundary line are connected, and the obtained area is the region of interest, which is of course not limited to this.

[0117] By determining the first characteristic point of the endometrium in the uterine ultrasound image and automatically connecting the first characteristic point according to the direction of the endometrium, the endometrial boundary line of the endometrium is formed. The endometrial boundary line can be used as the boundary of the region of interest, so that the boundaries of the region of interest on both sides of the endometrium can be determined based on the determined endometrial boundary line; at the same time, through the characteristic points located on the cervix and the characteristic points located on the fundus of the uterus, the end points of the endometrial boundary line at the cervix and the fundus of the uterus can be limited; therefore, the region of interest determined in the embodiment of the present application is more accurate, and the interference caused by movement outside the region of interest to the observation and analysis of peristalsis can be eliminated, and the observation range can be better locked to only the endometrium or the junction zone area.

[0118] In other embodiments, the first characteristic point of the endometrium in the uterine ultrasound image includes a characteristic point located on the first side of the endometrium. For example, when determining the first characteristic point of the endometrium, the characteristic point of the endometrium on one side may be determined. Figure 5 , determine feature points 1 to 4 of the first side inner membrane.

[0119] Exemplarily, the method of automatically connecting the first feature points including the feature points of the cervix and the feature points of the fundus according to the direction of the endometrium to form the endometrial boundary line of the endometrium includes: automatically connecting the feature points of the cervix and the feature points of the fundus located on the first side endometrium one by one according to the direction of the endometrium to form a first side endometrial boundary line; and generating a second side endometrial boundary line at a position close to the second side endometrium based on the first side endometrial boundary line.

[0120] Exemplarily, according to the direction of the endometrium, the feature points at one end of the first endometrium are automatically connected one by one to the feature points at the other end to form a first endometrial boundary line.

[0121] See also Figure 5 According to the direction of the endometrium, feature points 1 to 4 are automatically connected to form an anterior membrane boundary line; and a posterior membrane boundary line can be generated based on the anterior membrane boundary line.

[0122] Exemplarily, the shape of the second side endocardial boundary line generated based on the first side endocardial boundary line is the same as the shape of the first side endocardial boundary line, or it may be different, for example, the length of the generated second side endocardial boundary line is not equal to that of the first side endocardial boundary line; exemplarily, the second side endocardial boundary line generated based on the first side endocardial boundary line is parallel to the first side endocardial boundary line, but is not limited to this.

[0123] For example, see Figure 5 , generating a second lateral intima boundary line at a position close to the second lateral intima based on the first lateral intima boundary line, including: copying the first lateral intima boundary line and moving it toward the second lateral intima by a first preset distance to obtain the second lateral intima boundary line. For example, Figure 5 As shown, the direction of movement of the copied first-side endometrial boundary line can be a vertical direction; in other embodiments, the direction of movement of the copied first-side endometrial boundary line can be a normal direction of the first-side endometrial boundary line at a position, that is, a perpendicular direction of the tangent; for example, the direction of movement of the copied first-side endometrial boundary line is a normal direction of the first-side endometrial boundary line at a characteristic point of the first-side endometrium (such as a characteristic point of the cervix or a characteristic point of the fundus).

[0124] For example, the first feature point of the endometrium in the uterine ultrasound image also includes a feature point located on the second side of the endometrium, see Figure 6 , the first feature point also includes a posterior endometrial feature point 6. For example, the method of generating a second endometrial boundary line at a position close to the second endometrium based on the first endometrial boundary line includes: copying the first endometrial boundary line and moving it to coincide with at least one feature point of the second endometrium to obtain the second endometrial boundary line. For example, the direction of movement of the copied first endometrial boundary line can be a vertical direction; in other embodiments, the direction of movement of the copied first endometrial boundary line can be a normal direction of the first endometrial boundary line at a position. Of course, it is not limited to this. For example, the direction of movement of the copied first endometrial boundary line can be determined based on the fundus feature points of the first endometrium and the fundus feature points of the second endometrium, or the direction of movement of the copied first endometrial boundary line can be determined based on the cervical feature points of the first endometrium and the cervical feature points of the second endometrium.

[0125] In some other embodiments, the first characteristic point of the endometrium in the uterine ultrasound image includes a characteristic point located on the first side of the endometrium; the first characteristic point of the endometrium in the uterine ultrasound image also includes a characteristic point located on the second side of the endometrium; wherein the characteristic point of the second side of the endometrium includes a point located near the second side of the endometrium and at a second preset distance from the characteristic point of the first side of the endometrium according to the direction of a perpendicular line to the characteristic point of the first side of the endometrium, or the characteristic point of the second side of the endometrium includes a point located near the second side of the endometrium and at a third preset distance from the characteristic point of the first side of the endometrium according to the direction of a perpendicular line to the boundary line generated according to the characteristic point of the first side of the endometrium, and the perpendicular line passes through the characteristic point of the first side of the endometrium. The second distance and the third distance can be equal or different.

[0126] Exemplarily, determining a first characteristic point of the endometrium in the uterine ultrasound image includes: determining a characteristic point of a first endometrium in the uterine ultrasound image; and determining a point that is proximal to the second endometrium in a perpendicular direction to the characteristic point of the first endometrium and is a second preset distance away from the characteristic point of the first endometrium as the characteristic point of the second endometrium. Determining the characteristic point of the second endometrium using the characteristic point of the first endometrium and a vertical direction (perpendicular direction) is convenient and quick.

[0127] Exemplarily, determining the first characteristic point of the endometrium in the uterine ultrasound image includes: determining characteristic points of the endometrium on a first side of the endometrium in the uterine ultrasound image; and determining, as the characteristic point of the second side of the endometrium, a point that is close to the endometrium on the second side of the endometrium in a direction perpendicular to a boundary line generated from the characteristic points of the first side of the endometrium and is a third preset distance away from the characteristic points of the first side of the endometrium. The characteristic points of the second side of the endometrium are more accurately determined by determining the characteristic points of the second side of the endometrium using a curve generated from the characteristic points of the first side of the endometrium and the normal direction of each characteristic point on the curve.

[0128] See also Figure 7 According to the characteristic points 1 to 4 of the first side endofilm, characteristic points 1' to 4' of the second side endofilm are determined at positions close to the second side endofilm; optionally, the characteristic points of the second side endofilm determined may be less than or equal to the characteristic points of the first side endofilm.

[0129] Exemplarily, according to the direction of the endometrium, the characteristic points of the cervix and the fundus located on the first side of the endometrium are automatically connected to form the first side endometrial boundary line of the endometrium; based on the vertical direction of the first characteristic point of the first side endometrial boundary line and the two preset distances, the characteristic point of the second side endometrium is determined at a position close to the second side endometrium.

[0130] See also Figure 7 , the user traces at least two feature points on one side of the endometrium (at least one point each at the cervix and fundus), the system generates a unilateral curve based on the feature points, and then obtains the feature points on the other side based on the perpendicular segment of the tangent of the feature points on the unilateral curve (the length corresponding to the second preset distance). Exemplarily, the second preset distances corresponding to different first feature points may be equal or unequal, for example, the second preset distance corresponding to the feature point at the cervix is ​​less than or equal to the second preset distance corresponding to the feature point at the fundus, for example, the second preset distances corresponding to the feature points of the first side of the endometrium are arranged in arithmetical order, geometric proportions, or follow other specific rules. In some embodiments, the second preset distance can be set or adjusted by the user.

[0131] Exemplarily, the method of automatically connecting the first feature points including the feature points of the cervix and the feature points of the fundus according to the direction of the endometrium to form the endometrial boundary line of the endometrium includes: automatically connecting the feature points of the cervix and the feature points of the fundus located on the first side of the endometrium according to the direction of the endometrium to form the first side endometrial boundary line of the endometrium; and automatically connecting the feature points of the cervix and the feature points of the fundus located on the second side of the endometrium according to the direction of the endometrium to form the second side endometrial boundary line of the endometrium.

[0132] like Figure 7 As shown, the user traces several points along the edge of the anterior uterine membrane, with the initial point being feature point 1 at the position of the anterior uterine membrane at the fundus. Several feature points 1 to 4 are marked along the anterior membrane toward the cervix, and feature points 1 to 4 are automatically connected to generate the anterior membrane boundary line; the perpendicular direction of the tangent of the anterior membrane boundary line at each position of feature point 1 to feature point 4 is found, and corresponding specific lengths are automatically generated in the direction of the posterior membrane, such as perpendicular line segments with lengths of 15, 26, 37, and 48, respectively. The ends of the perpendicular line segments can be determined as feature points of the posterior uterine membrane, such as feature point 1' to feature point 4'. Automatically connecting feature point 1' to feature point 4' can generate the posterior membrane boundary line.

[0133] Exemplarily, the feature points forming the second-side intima boundary line include: a feature point located in the second-side intima among the first feature points, and a point that is close to the second-side intima based on a perpendicular direction of the feature point of the first-side intima and is a second preset distance away from the feature point of the first-side intima. For example, the feature points of the second-side intima determined based on image recognition and / or a user's feature point selection operation, as well as the feature points of the second-side intima determined based on the feature points of the first-side intima, can be used together to form the second-side intima boundary line, so that the second-side intima boundary can be more accurate, or the user can determine fewer feature points to save workload.

[0134] In some embodiments, the region of interest further includes: generating a uterine fundus region based on the feature points located at the uterine fundus, and / or generating a uterine cervix region based on the feature points located at the uterine cervix. Figure 8 The area between the endometrial boundary lines can be called region A, the uterine fundus region generated based on the feature points located at the uterine fundus can be called region B, and the cervical region generated based on the feature points located at the cervix can be called region C. The closed loop region formed by regions A, B, and C can be used to determine the region of interest, such as the intersection. The region of interest can more fully reflect uterine peristalsis.

[0135] Exemplarily, the fundus region and the cervix region may include one or more of the following shapes: circle, ellipse, rectangle, polygon, but are certainly not limited thereto and may be set by the user, for example.

[0136] For example, when the uterine ultrasound image is a longitudinal section ultrasound image, the uterine fundus region is a circular region, and the cervix region is a rectangular region, so that the region of interest determined in the longitudinal section ultrasound image can be more accurate.

[0137] For example, when the uterine ultrasound image is a transverse ultrasound image, the uterine fundus region and the cervical region are both circular regions, which can make the region of interest determined in the transverse ultrasound image more accurate.

[0138] Exemplarily, the circular area is tangent to the intimal boundary line at least at one point (eg, tangent to the anterior membrane boundary line), and / or at least one vertex of the rectangular area is located on the intimal boundary line.

[0139] Exemplarily, generating the fundus region based on the feature points located at the fundus of the uterus, and / or generating the cervix region based on the feature points located at the cervix of the uterus, includes: generating the fundus region based on the endpoint of the boundary line located at the fundus of the uterus on the endometrial boundary line in the uterine ultrasound image; generating the cervix region based on the endpoint of the boundary line located at the cervix on the endometrial boundary line in the uterine ultrasound image. For example, refer to Figure 8 , a circular area B can be automatically generated as the fundus region based on the marked anterior fundus membrane feature point 1 and posterior fundus membrane feature point 6. This circular area can have a diameter of the line connecting the anterior fundus membrane feature point 1 and the posterior fundus membrane feature point 6, or it can be tangent to the anterior membrane boundary line and the posterior membrane boundary line. Connect the anterior cervical membrane feature point 4 and the posterior cervical membrane feature point 5, and extend toward the cervix along the tangent direction of the anterior membrane boundary line and / or the posterior membrane boundary line corresponding to the anterior cervical membrane feature point 4 and the posterior cervical membrane feature point 5 to form a rectangular area C as the cervical region. Of course, this is not limited to this. For example, the anterior cervical membrane feature point 4 and the posterior cervical membrane feature point 5 can be directly connected to form the boundary of the region of interest at the cervix.

[0140] For example, the size and position of the fundus and cervix regions can also be set by the user. For example, the radius, position, and shape of the circular region B and the size, orientation, and shape of the rectangular region C can be adjusted. Optionally, feature points on the curve can also be edited.

[0141] For example, the identification of each area may be displayed or not, and the areas may be displayed together or separately; area A, area B, and area C may generate only one of A, B, and C, or two or all three.

[0142] For example, the identification of feature points and regions is not limited to identification such as color, shape, number, text, voice, brightness, transparency, and graph.

[0143] The method for determining the region of interest in an ultrasound image provided in an embodiment of the present application forms an endometrial boundary line of the endometrium by determining a first feature point of the endometrium in a uterine ultrasound image and automatically connecting the first feature point according to the direction of the endometrium, so that the boundaries of the region of interest on both sides of the endometrium can be determined based on the determined endometrial boundary line; at the same time, the first feature point includes a feature point located at the cervix and a feature point located at the fundus, which can define the endpoints of the endometrial boundary line at the cervix and the fundus; the region of interest in the uterine ultrasound image can be identified more accurately, and interference with the observation and analysis of peristalsis caused by movement outside the region of interest can be eliminated, so that the observation range can be better locked to only the endometrium or the junction zone area.

[0144] For example, the method of the embodiment of the present application can save the user's workload and is more efficient than simply determining the shape of the region of interest by manually tracing the endometrial / junctional band morphology; compared with existing technologies for automatic endometrial identification, such as artificial intelligence directly identifying the region of interest, it has higher accuracy and stability.

[0145] Please refer to the above examples. Figure 9 , Figure 9 This is a flowchart of a method for determining a region of interest in an ultrasound image provided by another embodiment of the present application.

[0146] like Figure 9 As shown, the method of the embodiment of the present application includes steps S210 to S240.

[0147] S210, acquiring a uterine ultrasound image, and displaying the uterine ultrasound image through a display interface of a display;

[0148] S220: Determine first feature points of the endometrium in the uterine ultrasound image, where the first feature points include feature points located at the cervix and feature points located at the fundus of the uterus;

[0149] S230: Automatically connect the first feature points one by one from the feature points at one end of the endometrium to the feature points at the other end of the endometrium according to the direction of the endometrium, to form an endometrial boundary line of the endometrium.

[0150] One end of the endometrium is the cervix, and the other end of the endometrium is the fundus, or one end of the endometrium is the fundus, and the other end of the endometrium is the cervix;

[0151] S240: Determine at least the region between the endometrial boundary lines in the uterine ultrasound image as the region of interest.

[0152] Optionally, the first feature points of the endometrium in the uterine ultrasound image include feature points located on a first side of the endometrium and feature points located on a second side of the endometrium, the first side of the endometrium being the anterior uterine lining and the second side of the endometrium being the posterior uterine lining, or the first side of the endometrium being the posterior uterine lining and the second side of the endometrium being the anterior uterine lining. Automatically connecting the first feature points from feature points at one end of the endometrium to feature points at the other end of the endometrium according to the direction of the endometrium to form an endometrial boundary line of the endometrium comprises: automatically connecting feature points at one end of the first side of the endometrium to feature points at the other end of the endometrium according to the direction of the endometrium to form a first endometrial boundary line; and automatically connecting feature points at one end of the second side of the endometrium to feature points at the other end of the endometrium according to the direction of the endometrium to form a second endometrial boundary line. Determining the region between at least the endometrial boundary lines in the uterine ultrasound image as the region of interest comprises: determining the region between at least the first endometrial boundary line and the second endometrial boundary line in the uterine ultrasound image as the region of interest.

[0153] Optionally, the first feature points of the endometrium in the uterine ultrasound image include feature points located on a first side of the endometrium, and the first side of the endometrium is the anterior uterine membrane or the posterior uterine membrane; the first feature points are automatically connected one by one from the feature points at one end of the endometrium to the feature points at the other end of the endometrium according to the direction of the endometrium to form the endometrial boundary line of the endometrium, including: according to the direction of the endometrium, the feature points located at one end of the first side of the endometrium are automatically connected one by one to the feature points at the other end to form the first side of the endometrial boundary line; based on the first side of the endometrial boundary line, a second side of the endometrial boundary line is generated at a position close to the second side of the endometrium, wherein the second side of the endometrium and the first side of the endometrium are endometriums on different sides.

[0154] Optionally, generating a second lateral endocardial boundary line at a position close to the second lateral endocardium based on the first lateral endocardial boundary line includes: copying the first lateral endocardial boundary line and moving it a first preset distance toward the second lateral endocardium to obtain the second lateral endocardial boundary line.

[0155] Optionally, the first feature point of the endometrium in the uterine ultrasound image also includes a feature point located on the second side endometrium; generating the second side endometrial boundary line at a position close to the second side endometrium based on the first side endometrial boundary line includes: copying the first side endometrial boundary line and moving it to overlap with at least one feature point of the second side endometrium to obtain the second side endometrial boundary line.

[0156] Optionally, determining the first feature point of the endometrium in the uterine ultrasound image includes: determining the feature point of the first side endometrium in the uterine ultrasound image; taking a point that is close to the second side endometrium in the direction of a vertical line based on the feature point of the first side endometrium and is at a second preset distance from the feature point of the first side endometrium as the feature point of the second side endometrium, or taking a point that is close to the second side endometrium in the direction of a vertical line based on the boundary line generated from the feature point of the first side endometrium and is at a third preset distance from the feature point of the first side endometrium as the feature point of the second side endometrium, and the vertical line passes through the feature point of the first side endometrium.

[0157] Optionally, the region of interest further includes: generating a uterine fundus region based on the feature points located at the uterine fundus, and / or generating a cervical region based on the feature points located at the cervix.

[0158] Optionally, when the uterine ultrasound image is a longitudinal section ultrasound image, the uterine fundus area is a circular area, and the cervical area is a rectangular area; optionally, when the uterine ultrasound image is a transverse section ultrasound image, the uterine fundus area and the cervical area are both circular areas.

[0159] Optionally, the circular area is tangent to the intimal boundary line at least at one location, and / or at least one vertex of the rectangular area is located on the intimal boundary line.

[0160] Optionally, generating the fundus region based on the feature points located at the fundus of the uterus, and / or generating the cervix region based on the feature points located at the cervix, includes: generating the fundus region based on the endpoint of the boundary line located at the fundus of the uterus on the endometrial boundary line in the uterine ultrasound image; generating the cervix region based on the endpoint of the boundary line located at the cervix on the endometrial boundary line in the uterine ultrasound image.

[0161] Optionally, determining the first feature point of the endometrium in the uterine ultrasound image includes: determining the first feature point of the endometrium in the uterine ultrasound image based on image recognition and / or a feature point selection operation of a user.

[0162] Optionally, the user-based feature point selection operation to determine the first feature point of the endometrium in the uterine ultrasound image includes: receiving the user's feature point selection operation from one end to the other end of the endometrium according to the direction of the endometrium, to obtain the first feature point of the endometrium in the uterine ultrasound image.

[0163] Optionally, the method further includes: identifying the area where the endometrium is located, and determining the direction of the endometrium based on the area where the endometrium is located; or identifying the lateral endometrium of the endometrium, and determining the direction of the endometrium based on the direction of the lateral endometrium of the endometrium.

[0164] Please refer to the above examples. Figure 10 , Figure 10 This is a flowchart of a method for determining a region of interest in an ultrasound image provided by another embodiment of the present application.

[0165] like Figure 10 As shown, the method of the embodiment of the present application includes steps S310 to S350.

[0166] S310, acquiring a uterine ultrasound image, and displaying the uterine ultrasound image through a display interface of a display;

[0167] S320: Determine first feature points of the endometrium in the uterine ultrasound image, where the first feature points include feature points located at the cervix and feature points located at the fundus of the uterus.

[0168] S330: Automatically connect characteristic points of the first side of the endometrium from one end to the other end according to the direction of the endometrium to form a boundary line of the first side of the endometrium;

[0169] S340 , according to the direction of the endometrium, automatically connect the feature points of the second side endometrium of the endometrium one by one from the feature points at the other end to the feature points at one end, to form a boundary line of the second side endometrium.

[0170] Wherein, the first-side endometrium is the anterior uterine membrane, and the second-side endometrium is the posterior uterine membrane, or the first-side endometrium is the posterior uterine membrane, and the second-side endometrium is the anterior uterine membrane.

[0171] S350: Determine in the uterine ultrasound image at least a region between the first endometrial boundary line and the second endometrial boundary line as the region of interest.

[0172] It is characterized in that the characteristic points forming the boundary line of the second side endometaphase include: the characteristic points of the first characteristic points located in the second side endometaphase, and the points close to the second side endometaphase according to the perpendicular direction of the characteristic points of the first side endometaphase, and the distance from the characteristic points of the first side endometaphase to the second side endometaphase is a second preset distance.

[0173] Optionally, the region of interest further includes: generating a uterine fundus region based on the feature points located at the uterine fundus, and / or generating a cervical region based on the feature points located at the cervix.

[0174] Optionally, when the uterine ultrasound image is a longitudinal section ultrasound image, the uterine fundus area is a circular area, and the cervical area is a rectangular area; optionally, when the uterine ultrasound image is a transverse section ultrasound image, the uterine fundus area and the cervical area are both circular areas.

[0175] Optionally, the circular area is tangent to the intimal boundary line at least at one location, and / or at least one vertex of the rectangular area is located on the intimal boundary line.

[0176] Optionally, generating the fundus region based on the feature points located at the fundus of the uterus, and / or generating the cervix region based on the feature points located at the cervix, includes: generating the fundus region based on the endpoint of the boundary line located at the fundus of the uterus on the endometrial boundary line in the uterine ultrasound image; generating the cervix region based on the endpoint of the boundary line located at the cervix on the endometrial boundary line in the uterine ultrasound image.

[0177] Optionally, determining the first feature point of the endometrium in the uterine ultrasound image includes: determining the first feature point of the endometrium in the uterine ultrasound image based on image recognition and / or a feature point selection operation of a user.

[0178] Optionally, the method further includes: identifying the area where the endometrium is located, and determining the direction of the endometrium based on the area where the endometrium is located; or identifying the lateral endometrium of the endometrium, and determining the direction of the endometrium based on the direction of the lateral endometrium of the endometrium.

[0179] Please refer to the above examples. Figure 11 , Figure 11 This is a flowchart of a method for determining a region of interest in an ultrasound image provided in yet another embodiment of the present application.

[0180] like Figure 11 As shown, the method of the embodiment of the present application includes steps S410 to S450.

[0181] S410: Acquire a uterine ultrasound image, and display the uterine ultrasound image through a display interface of a display.

[0182] S420: Determine second feature points in the uterine cavity of the endometrium in the uterine ultrasound image, wherein the second feature points include feature points located at the cervix and feature points located at the fundus of the uterus.

[0183] See also Figure 12 The second feature point in the uterine cavity includes feature point 1 to feature point 4, wherein feature point 1 is a feature point located at the uterine fundus and feature point 4 is a feature point located at the cervix. For example, the second feature point of the uterine cavity midline in the uterine ultrasound image is determined.

[0184] Exemplarily, based on image recognition and / or a user's feature point selection operation, a second feature point in the uterine cavity of the hysterosalplasty image is determined. For example, the second feature point can be manually determined by the user, automatically determined, or manually adjusted by the user after automatic determination. For details, please refer to the aforementioned implementation method for determining the first feature point, and will not be further described here.

[0185] Exemplarily, a user operation is received to select a feature point from one end of the uterine cavity to the other end thereof according to the direction of the endometrium, thereby obtaining a second feature point in the uterine cavity of the endometrium in the uterine ultrasound image. One end of the uterine cavity is the cervix and the other end of the uterine cavity is the uterine fundus, or one end of the uterine cavity is the uterine fundus and the other end of the uterine cavity is the cervix.

[0186] It should be noted that the number of the second characteristic point in the uterine cavity may or may not be displayed.

[0187] S430: Automatically connect the second feature points including the feature points of the cervix and the feature points of the uterine fundus according to the direction of the endometrium to form a uterine cavity line of the endometrium.

[0188] See also Figure 12 , automatically connect feature points 1 to 4 in the uterine cavity to form the uterine cavity line of the endometrium.

[0189] Exemplarily, according to the direction of the endometrium, the second characteristic points are automatically connected one by one from the characteristic points at one end of the uterine cavity to the characteristic points at the other end of the uterine cavity to form a uterine cavity line of the endometrium, wherein one end of the uterine cavity is the cervix and the other end of the uterine cavity is the uterine fundus, or one end of the uterine cavity is the uterine fundus and the other end of the uterine cavity is the cervix.

[0190] For example, when the second feature points are automatically connected, they may be connected in a straight line or in an arc line, but this is not limited thereto. For example, they may also be connected in a broken line.

[0191] Exemplarily, the uterine cavity line formed by automatically connecting the second feature points may be a broken line segment, a straight line, or a regular or irregular curve, etc., and there is no limitation to this.

[0192] Exemplarily, the method further includes: identifying an area where the endometrium is located, and determining a direction of the endometrium according to the area where the endometrium is located.

[0193] Exemplarily, the method further includes: identifying the lateral endometrium of the endometrium, and determining the direction of the endometrium according to the direction of the lateral endometrium of the endometrium.

[0194] Illustratively, at least a portion of the uterine cavity line formed in step S430 is parallel to the direction of the endometrium, such as a line connecting at least two adjacent second characteristic points is parallel to the direction of the endometrium.

[0195] S440: Generate an anterior membrane boundary line and a posterior membrane boundary line based on the uterine cavity line.

[0196] The uterine cavity line is formed by automatically connecting the second feature points including the feature points of the cervix and the feature points of the uterine fundus according to the direction of the endometrium. Therefore, the shape of the uterine cavity line is substantially the same as the shape of the anterior uterine membrane and / or the posterior uterine membrane. The anterior uterine membrane boundary line and the posterior uterine membrane boundary line can be generated by, for example, translating the uterine cavity line. The anterior uterine membrane boundary line is used to indicate the boundary of the anterior uterine membrane, and the posterior uterine membrane boundary line is used to indicate the boundary of the posterior uterine membrane.

[0197] In some embodiments, generating the anterior membrane boundary line and the posterior membrane boundary line based on the uterine cavity line includes: moving the uterine cavity line toward the position of the first endometrium to obtain the first endometrium boundary line, where the first endometrium is the anterior uterine membrane or the posterior uterine membrane; copying the first endometrium boundary line and moving it toward the position of the second endometrium to obtain the second endometrium boundary line, where the second endometrium and the first endometrium are endometriums on different sides. Figure 12 , move the uterine cavity line indicated by feature points 1 to 4 upward to obtain the anterior membrane boundary line; move the anterior membrane boundary line downward to obtain the posterior membrane boundary line.

[0198] In other embodiments, generating the anterior membrane boundary line and the posterior membrane boundary line based on the uterine cavity line includes: duplicating the uterine cavity line to obtain two uterine cavity lines; moving one of the uterine cavity lines toward the position of the anterior uterine membrane to obtain the anterior membrane boundary line; and moving the other of the two uterine cavity lines toward the direction of the posterior uterine membrane to obtain the posterior membrane boundary line. Figure 12 , move the uterine cavity line indicated by feature points 1 to 4 upward to obtain the anterior membrane boundary line; move the uterine cavity line downward to obtain the posterior membrane boundary line.

[0199] For example, when moving the uterine cavity line or the first endometrial boundary line generated based on the uterine cavity line, the direction of movement can be vertical, or can be the normal direction of the uterine cavity line or the first endometrial boundary line at a position, that is, the perpendicular direction of the tangent, for example, the normal direction of the uterine cavity line at a second feature point (such as a feature point of the cervix or a feature point of the fundus). Of course, this is not limited to this. For example, the direction of movement can be determined by the user, or determined based on the second feature point and the first feature point of the endometrium in the uterine ultrasound image. For example, the direction of movement is determined based on the second feature point of the fundus and the first feature point of the fundus.

[0200] For example, when the uterine cavity line or the first endometrial boundary line generated according to the uterine cavity line is moved, the moving distance may be a preset distance, or the moving distance may be adjusted according to the user's operation.

[0201] Exemplarily, the method also includes determining a first characteristic point of the endometrium in a uterine ultrasound image, such as a first characteristic point of the anterior uterine membrane and / or the posterior uterine membrane; when moving the uterine cavity line to generate a first side endometrial boundary line or a second side endometrial boundary line, moving to a position that coincides with the first characteristic point of at least one anterior uterine membrane or posterior uterine membrane; when moving the first side endometrial boundary line to obtain a second side endometrial boundary line, moving to a position that coincides with the first characteristic point of at least one anterior uterine membrane or posterior uterine membrane.

[0202] In some other embodiments, generating the anterior membrane boundary line and the posterior membrane boundary line based on the uterine cavity line includes: determining the characteristic points of the anterior uterine membrane and the characteristic points of the posterior uterine membrane based on the uterine cavity line and the second characteristic points; determining the anterior membrane boundary line according to the characteristic points of the anterior uterine membrane, and determining the posterior membrane boundary line according to the characteristic points of the posterior uterine membrane.

[0203] Exemplarily, a point that is close to the preuterine membrane in the normal direction or the perpendicular direction of the uterine cavity line and is at a third preset distance from the second characteristic point is used as a characteristic point of the preuterine membrane.

[0204] See also Figure 12 , based on the characteristic points 1 to 4 of the uterine cavity, characteristic points 1' to 4' of the preuterine membrane are determined at positions close to the preuterine membrane; optionally, the determined characteristic points of the preuterine membrane may be less than or equal to the second characteristic point.

[0205] Exemplarily, a point located in the normal direction or perpendicular direction of the curve corresponding to the uterine cavity line, close to the posterior uterine membrane and at a fourth preset distance from the second feature point, is used as a feature point of the posterior uterine membrane. For example, the feature points of the anterior uterine membrane are automatically connected according to the direction of the endometrium to form the anterior uterine membrane boundary line. It should be noted that forming the anterior uterine membrane boundary line may also include determining the first feature point of the anterior uterine membrane based on image recognition and / or a user's feature point selection operation, so that the second-side endometrial boundary can be more accurate.

[0206] See also Figure 12, based on the feature points 1 to 4 of the uterine cavity, feature points 1" to 4" of the posterior uterine membrane are determined at a position close to the posterior uterine membrane; optionally, the feature points of the posterior uterine membrane determined may be less than or equal to the second feature point. For example, according to the direction of the posterior uterine membrane, the feature points of the posterior uterine membrane are automatically connected to form the posterior membrane boundary line. It should be noted that the formation of the posterior membrane boundary line may also include determining the first feature point of the posterior uterine membrane based on image recognition and / or the user's feature point selection operation, so that the second side endometrial boundary can be more accurate.

[0207] For example, the third and fourth preset distances corresponding to different second feature points may be equal or unequal; for example, the third preset distance corresponding to a feature point at the cervix may be less than or equal to the third preset distance corresponding to a feature point at the fundus; for example, the third preset distances corresponding to the second feature points may be arranged in arithmetic progression, geometric proportions, or follow other specific patterns. In some embodiments, the third and fourth preset distances may be set or adjusted by the user.

[0208] S450: Determine at least a region between the anterior membrane boundary line and the posterior membrane boundary line in the uterine ultrasound image as the region of interest.

[0209] See also Figure 12 , determine at least the area between the anterior membrane boundary line corresponding to the feature points 1 ' to the feature points 4' and the posterior membrane boundary line corresponding to the feature points 1" to the feature points 4" as the region of interest.

[0210] Exemplarily, the two ends of the anterior membrane boundary line and the two ends of the posterior membrane boundary line are connected, and the obtained area is the region of interest, which is of course not limited to this.

[0211] In some embodiments, the region of interest further includes: generating a uterine fundus region at the end of the anterior membrane boundary line and the posterior membrane boundary line near the uterine fundus, and / or generating a cervical region at the end near the cervix. For details, please refer to the description of the uterine fundus region and the cervical region in the previous embodiments and are not repeated here.

[0212] Exemplarily, when the uterine ultrasound image is a longitudinal section ultrasound image, the uterine fundus area is a circular area, and the cervical area is a rectangular area; and / or when the uterine ultrasound image is a transverse section ultrasound image, the uterine fundus area and the cervical area are both circular areas.

[0213] Exemplarily, the circular area is tangent to the anterior membrane boundary line or the posterior membrane boundary line at least at one location, and / or at least one vertex of the rectangular area is located on the anterior membrane boundary line or the posterior membrane boundary line.

[0214] Exemplarily, generating the fundus region based on the feature points located at the fundus of the uterus, and / or generating the cervix region based on the feature points located at the cervix, includes: generating the fundus region based on the boundary line endpoint of the anterior membrane boundary line located at the fundus of the uterus and the boundary line endpoint of the posterior membrane boundary line located at the fundus of the uterus in the uterine ultrasound image; and / or generating the fundus region based on the boundary line endpoint of the anterior membrane boundary line located at the cervix and the boundary line endpoint of the posterior membrane boundary line located at the cervix in the uterine ultrasound image.

[0215] The embodiment of the present application provides a method for determining a region of interest in an ultrasound image, which forms a uterine cavity line of the endometrium by determining a second feature point in the uterine cavity of the endometrium in the uterine ultrasound image, and automatically connecting the second feature points including the feature points of the cervix and the feature points of the fundus according to the direction of the endometrium; an anterior membrane boundary line and a posterior membrane boundary line can be generated based on the uterine cavity line, and the boundaries of the region of interest on both sides of the endometrium can be determined based on the area between the anterior membrane boundary line and the posterior membrane boundary line; at the same time, the second feature point includes a feature point located on the cervix and a feature point located on the fundus, which can define the end points of the endometrial boundary line at the cervix and the fundus; the region of interest in the uterine ultrasound image can be identified more accurately, and the interference of movement outside the region of interest on the observation and analysis of peristalsis caused by elimination, so as to better lock the observation range to only the endometrium or the junction zone area.

[0216] In some embodiments, the region of interest may not cover the entire endometrium, for example, only a unilateral endometrial region may need to be covered. Exemplarily, the method includes: acquiring a uterine ultrasound image and displaying the uterine ultrasound image through a display interface of a display; determining second feature points in the uterine cavity of the endometrium in the uterine ultrasound image, wherein the second feature points include feature points located at the cervix and feature points located at the fundus; automatically connecting the second feature points including the feature points of the cervix and the fundus according to the direction of the endometrium to form a uterine cavity line of the endometrium; generating an anterior membrane boundary line and / or a posterior membrane boundary line based on the uterine cavity line; and determining the region between at least any two of the anterior membrane boundary line, the posterior membrane boundary line, and the uterine cavity line in the uterine ultrasound image as the region of interest.

[0217] For example, an anterior membrane boundary line is generated based on the uterine cavity line, and the area between the anterior membrane boundary line and the uterine cavity line is the region of interest. The anterior membrane boundary line can be obtained by copying and moving the uterine cavity line, or by determining a first feature point based on a perpendicular line to the uterine cavity line and automatically connecting the first feature points.

[0218] In some embodiments, see Figure 13, determine the first feature point on the endometrium side of the uterine ultrasound image, such as feature point 1 to feature point 4 of the preuterine membrane; automatically connect the first feature point according to the direction of the endometrium to form the endometrial boundary line on one side of the endometrium (the curve indicated by feature point 1 to feature point 4 can be called the preuterine membrane boundary line); the uterine cavity line can be obtained according to the endometrial boundary line on one side of the endometrium, such as the curve indicated by feature point 1' to feature point 4'; determine the area between the endometrial boundary line on at least one side of the endometrium in the uterine ultrasound image and the uterine cavity line as the region of interest. The uterine cavity line can be obtained by copying and moving the endometrial boundary line on one side of the endometrium, or by determining the second feature point of the uterine cavity according to the perpendicular line of the endometrial boundary line on one side of the endometrium (such as Figure 13 Feature point 1' to feature point 4') in the image, and automatically connect the second feature point.

[0219] For example, see Figure 14 The region of interest may also include a uterine fundus region generated at one end of the anterior membrane boundary line and / or the posterior membrane boundary line close to the uterine fundus, and / or a cervical region generated at one end close to the cervix. Feature points p1 and p2 are first feature points of the anterior uterine membrane or the posterior uterine membrane determined based on image recognition and / or a feature point selection operation by the user. The uterine fundus region and the cervical region may be generated based on the anterior membrane boundary line formed according to the uterine cavity line and the first feature point of the posterior uterine membrane; or the uterine fundus region and / or the cervical region may be generated based on the posterior membrane boundary line formed according to the uterine cavity line and the first feature point of the anterior uterine membrane.

[0220] In some embodiments, the region of interest includes an endometrium / junction zone region on one side of the uterus. Exemplarily, the method includes: acquiring a uterine ultrasound image, and displaying the uterine ultrasound image via a display interface of a display;

[0221] Determine first feature points of the first side endometrium in the uterine ultrasound image, wherein the first feature points include feature points located at the cervix and feature points located at the fundus; wherein the first side endometrium includes the anterior uterine membrane or the posterior uterine membrane of the endometrium; according to the direction of the endometrium, automatically connect the first feature points including the feature points of the cervix and the feature points of the fundus to form a first boundary line of the first side endometrium; generate a second boundary line away from the first side endometrium and close to the myometrium based on the first boundary line; determine the area between at least the first boundary line and the second boundary line in the uterine ultrasound image as the area of ​​interest.

[0222] See also Figure 15, determine the first feature points 1 to 4 of the anterior uterine membrane, automatically connect feature points 1 to 4 to form an anterior membrane boundary line; based on the anterior membrane boundary line, a second boundary line is generated at a point away from the first side endometrium and close to the myometrium, that is, on the side away from the uterine cavity according to the anterior membrane boundary line (such as the curve indicated by feature points 1' to 4'), and the second boundary line can be called the junction zone boundary line; the area between the anterior membrane boundary line and the second boundary line can be determined as the region of interest. For example, the two ends of the anterior membrane boundary line and the second boundary line are connected respectively, and the enclosed area is the region of interest. Of course, it is not limited to this. For example, the region of interest can also include at least one of the following: the fundus region, the cervical region, the area between any two of the anterior membrane boundary line, the posterior membrane boundary line, and the uterine cavity line.

[0223] For example, the second boundary line can be obtained by copying and moving the first boundary line, or by determining a feature point for indicating the second boundary line based on a perpendicular line of the first boundary line, such as Figure 15 Feature points 1' to 4' are automatically connected to obtain the second boundary line.

[0224] Please refer to the above examples. Figure 16 , Figure 16 This is a flowchart of a method for determining a region of interest in an ultrasound image provided in yet another embodiment of the present application.

[0225] like Figure 16 As shown, the method of the embodiment of the present application includes steps S510 to S540.

[0226] S510: Acquire a uterine ultrasound image, and display the uterine ultrasound image through a display interface of a display.

[0227] S520: Determine third feature points of the endometrium in the uterine ultrasound image, where the third feature points include feature points located at the cervix and feature points located at the fundus of the uterus.

[0228] See also Figure 17 The third characteristic points of the endometrium include characteristic points 1 to 6, wherein characteristic point 1 and / or characteristic point 6 are characteristic points located at the fundus of the uterus, and characteristic point 4 and / or characteristic point 5 are characteristic points located at the cervix.

[0229] Exemplarily, a third feature point of the endometrium in the uterine ultrasound image is determined based on image recognition and / or a user's feature point selection operation. For example, the third feature point may be manually determined by the user, automatically determined, or manually adjusted by the user after automatic determination. For details, refer to the aforementioned embodiment for determining the first feature point, and are not further described here.

[0230] S530 , automatically connecting the third characteristic points one by one along the shortest path according to the direction of the endometrium to form an endometrial boundary line of the endometrium.

[0231] See also Figure 17 , connecting adjacent third feature points in sequence according to the shortest path to form the endometrial boundary line of the endometrium; Figure 17 As shown, the endometrial boundary line of the endometrium may be closed, or may not be closed. For example, the endometrial boundary line may be a curve segment from feature point 1 through feature point 2 to feature point 5 to feature point 6.

[0232] For example, the third characteristic points are automatically connected one by one along the shortest path to form the endometrial boundary line of the endometrium. This eliminates the need for the user to determine the third characteristic points in a specific order, thereby increasing flexibility. For example, the third characteristic points can be automatically connected one by one along the shortest path according to a preset path planning algorithm to form the endometrial boundary line of the endometrium.

[0233] For example, the line connecting adjacent third feature points can be a straight line, which reduces computational complexity and improves data processing efficiency.

[0234] In some embodiments, the method further includes: identifying the area where the endometrium is located, and determining the direction of the endometrium based on the area where the endometrium is located; or identifying the lateral endometrium of the endometrium, and determining the direction of the endometrium based on the direction of the lateral endometrium of the endometrium.

[0235] In some embodiments, according to the direction of the endometrium, the third characteristic points are automatically connected one by one along the shortest path to form the endometrial boundary line of the endometrium, including: selecting a starting point from the third characteristic points; using the starting point to connect one by one in a counterclockwise / clockwise direction and along the shortest path to form the endometrial boundary line of the endometrium.

[0236] Exemplarily, the starting point is a feature point located on the cervix or the fundus of the uterus among the third feature points.

[0237] For example, see Figure 17 The starting point is the fundus feature point 1 of the anterior uterine membrane, and the ending point is the cervix feature point 6 of the posterior uterine membrane.

[0238] S540: Determine at least the region between the endometrial boundary lines in the uterine ultrasound image as the region of interest.

[0239] See also Figure 17, the area between the intima boundary lines is the region of interest, but is certainly not limited thereto.

[0240] Exemplarily, the region of interest further includes: generating a uterine fundus region at the end of the anterior membrane boundary line and the posterior membrane boundary line close to the uterine fundus, and / or generating a cervical region at the end close to the cervix. For details, please refer to the description of the uterine fundus region and the cervical region in the previous embodiment, which will not be repeated here.

[0241] Please refer to the above examples. Figure 2 , Figure 2 is a schematic block diagram of an ultrasonic imaging device 10 in one embodiment.

[0242] like Figure 2 As shown, the ultrasonic imaging device 10 includes at least a probe 100; a transmitting circuit 101, which stimulates the probe 100 to send ultrasonic waves to the uterus; a receiving circuit 103, which controls the probe 100 to receive ultrasonic echoes to obtain ultrasonic echo signals; and a display, which provides a display interface.

[0243] The ultrasonic imaging device 10 processes the ultrasonic echo signal to obtain a uterine ultrasonic image. Figure 2 The beamforming circuit 104 in the ultrasonic imaging device 10 performs beamforming processing on the ultrasonic echo signal / data and then sends the processed data to the processor 105. The processor 105 can process the ultrasonic echo signal / data to obtain a uterine ultrasonic image.

[0244] The ultrasonic imaging device 10 is further configured to execute the steps of the aforementioned method for determining a region of interest in an ultrasonic image, determining a region of interest in the uterine ultrasonic image. For example, the ultrasonic imaging device 10 includes one or more processors 105, which work individually or collectively to execute the steps of the method for determining a region of interest in an ultrasonic image, determining a region of interest in the uterine ultrasonic image.

[0245] The ultrasonic imaging device 10 is further configured to extract and process the ultrasonic echo signal of the region of interest to obtain peristaltic motion parameters of the region of interest; and to display a graph showing changes in the peristaltic motion parameters of the region of interest over time through the display interface of the display.

[0246] The specific principles and implementation methods of the ultrasonic imaging device provided in the embodiment of the present application are similar to the method for determining the region of interest in the ultrasonic image in the aforementioned embodiment, and will not be repeated here.

[0247] An embodiment of the present application further provides a computer-readable storage medium storing a computer program. When the computer program is executed by a processor, the processor implements the steps of the method for determining a region of interest in an ultrasound image provided in the above embodiment.

[0248] The computer-readable storage medium may be an internal storage unit of the ultrasound imaging device described in any of the aforementioned embodiments, such as a hard disk or memory of the ultrasound imaging device. The computer-readable storage medium may also be an external storage device of the ultrasound imaging device, such as a plug-in hard disk, a smart media card (SMC), a secure digital (SD) card, a flash card, etc., equipped on the ultrasound imaging device.

[0249] It should be understood that the terminology used herein is for the purpose of describing particular embodiments only and is not intended to be limiting of the present application.

[0250] It will also be understood that the term "and / or" as used in this application and the appended claims refers to and includes any and all possible combinations of one or more of the associated listed items.

[0251] The above description is merely a specific embodiment of the present application, but the scope of protection of the present application is not limited thereto. Any person skilled in the art can easily conceive of various equivalent modifications or substitutions within the technical scope disclosed in the present application, and such modifications or substitutions should be included in the scope of protection of the present application. Therefore, the scope of protection of the present application should be based on the scope of protection of the claims.

Claims

1. A method for determining a region of interest in an ultrasound image, characterized in that: include: Acquiring a uterine ultrasound image, and displaying the uterine ultrasound image through a display interface of a display; Determine first feature points of the endometrium in the uterine ultrasound image, where the first feature points include feature points located at the cervix and feature points located at the fundus of the uterus; automatically connecting the first feature points including the feature points of the cervix and the feature points of the fundus according to the direction of the endometrium to form an endometrial boundary line of the endometrium; determining at least a region between the endometrial boundary lines in the uterine ultrasound image as the region of interest; The method further comprises: Identifying the boundary of the region where the endometrium is located, and determining the direction of the endometrium according to the boundary of the region where the endometrium is located; or The lateral endometrium of the endometrium is identified, and the direction of the endometrium is determined according to the direction of the lateral endometrium of the endometrium.

2. The method according to claim 1, characterized in that The first feature points of the endometrium in the uterine ultrasound image include feature points located on the first side of the endometrium and feature points located on the second side of the endometrium. The first-side endometrium is the anterior uterine membrane, and the second-side endometrium is the posterior uterine membrane, or the first-side endometrium is the posterior uterine membrane, and the second-side endometrium is the anterior uterine membrane; The step of automatically connecting the first feature points including the feature points of the cervix and the feature points of the fundus according to the direction of the endometrium includes: According to the direction of the endometrium, the characteristic points of the cervix and the fundus of the first endometrium are automatically connected to form a boundary line of the first endometrium. Automatically connecting characteristic points of the cervix and the fundus of the second-side endometrium according to the direction of the endometrium to form a boundary line of the second-side endometrium; The determining of at least the region between the endometrial boundary lines in the uterine ultrasound image as the region of interest includes: At least a region between the first endometrial boundary line and the second endometrial boundary line in the uterine ultrasound image is determined as the region of interest.

3. The method according to claim 1, characterized in that The endometrium includes a first endometrium and a second endometrium, the first characteristic point of the endometrium in the uterine ultrasound image includes a characteristic point located on the first endometrium, and the first endometrium is anterior uterine membrane or posterior uterine membrane; The step of automatically connecting the first feature points including the feature points of the cervix and the feature points of the uterine fundus according to the direction of the endometrium to form an endometrial boundary line of the endometrium includes: According to the direction of the endometrium, the characteristic points of the cervix and the characteristic points of the fundus located on the first side of the endometrium are automatically connected one by one to form a boundary line of the first side of the endometrium; A second lateral intimal boundary line is generated at a position close to the second lateral intimal boundary line according to the first lateral intimal boundary line.

4. The method according to claim 3, characterized in that Generating a second intimal boundary line at a position close to the second intimal boundary line according to the first intimal boundary line includes: The first side intima boundary line is copied and moved toward the second side intima by a first preset distance to obtain the second side intima boundary line.

5. The method according to claim 3, characterized in that The first feature point of the endometrium in the uterine ultrasound image also includes a feature point located on the second side endometrium; Generating a second intimal boundary line at a position close to the second intimal boundary line according to the first intimal boundary line includes: The first intima boundary line is copied and moved to coincide with at least one characteristic point of the second intima to obtain the second intima boundary line.

6. The method according to claim 1, characterized in that The endometrium includes a first endometrium and a second endometrium. The first feature point of the endometrium in the uterine ultrasound image includes a feature point located on the first side endometrium; The first feature point of the endometrium in the uterine ultrasound image also includes a feature point located on the second side endometrium; The characteristic point of the second side inner membrane includes a point close to the second side inner membrane and a second preset distance away from the characteristic point of the first side inner membrane according to the direction of the perpendicular line of the characteristic point of the first side inner membrane, or the characteristic point of the second side inner membrane includes a point close to the second side inner membrane and a third preset distance away from the characteristic point of the first side inner membrane according to the direction of the perpendicular line of the boundary line generated according to the characteristic point of the first side inner membrane, and the perpendicular line passes through the characteristic point of the first side inner membrane.

7. The method according to claim 6, characterized in that The step of automatically connecting the first feature points including the feature points of the cervix and the feature points of the uterine fundus according to the direction of the endometrium to form an endometrial boundary line of the endometrium includes: Automatically connecting characteristic points of the cervix and the fundus located on the first side of the endometrium according to the direction of the endometrium to form a first side endometrial boundary line of the endometrium; According to the direction of the endometrium, the characteristic points of the cervix and the fundus located on the second side of the endometrium are automatically connected to form the second side endometrial boundary line of the endometrium.

8. The method according to claim 7, characterized in that The feature points forming the boundary line of the second side endometastasis include: the feature points of the first feature points located in the second side endometastasis, and the points close to the second side endometastasis according to the perpendicular direction of the feature points of the first side endometastasis, and the distance from the feature points of the first side endometastasis is a second preset distance.

9. The method according to any one of claims 1 to 8, characterized in that The region of interest further includes: A uterine fundus region is generated according to the feature points located at the uterine fundus, and / or a uterine cervix region is generated according to the feature points located at the uterine cervix.

10. The method according to claim 9, characterized in that When the uterine ultrasound image is a longitudinal section ultrasound image, the uterine fundus region is a circular region, and the cervical region is a rectangular region; When the uterine ultrasound image is a transverse ultrasound image, the uterine fundus region and the cervical region are both circular regions.

11. The method according to claim 10, characterized in that The circular area is tangent to the intimal boundary line at least at one location, and / or at least one vertex of the rectangular area is located on the intimal boundary line.

12. The method according to claim 9, characterized in that Generating a uterine fundus region according to the feature points located at the uterine fundus, and / or generating a cervical region according to the feature points located at the cervix, includes: generating the uterine fundus region according to the boundary line endpoint located at the uterine fundus on the endometrial boundary line in the uterine ultrasound image; The cervical region is generated according to the boundary line endpoint located at the cervix on the endometrial boundary line in the uterine ultrasound image.

13. The method according to any one of claims 1 to 8, characterized in that The determining of a first characteristic point of the endometrium in the uterine ultrasound image includes: Based on image recognition and / or a feature point selection operation by a user, a first feature point of the endometrium in the uterine ultrasound image is determined.

14. A method for determining a region of interest in an ultrasound image, characterized in that: include: Acquiring a uterine ultrasound image, and displaying the uterine ultrasound image through a display interface of a display; Determine first feature points of the endometrium in the uterine ultrasound image, where the first feature points include feature points located at the cervix and feature points located at the fundus of the uterus; automatically connecting the first feature points one by one from a feature point at one end of the endometrium to a feature point at the other end of the endometrium according to the direction of the endometrium to form an endometrial boundary line of the endometrium, wherein one end of the endometrium is the cervix and the other end of the endometrium is the fundus, or one end of the endometrium is the fundus and the other end of the endometrium is the cervix; determining at least a region between the endometrial boundary lines in the uterine ultrasound image as the region of interest; The method further comprises: Identifying the boundary of the region where the endometrium is located, and determining the direction of the endometrium according to the boundary of the region where the endometrium is located; or The lateral endometrium of the endometrium is identified, and the direction of the endometrium is determined according to the direction of the lateral endometrium of the endometrium.

15. The method according to claim 14, characterized in that The first feature points of the endometrium in the uterine ultrasound image include feature points located on the first side of the endometrium and feature points located on the second side of the endometrium. The first-side endometrium is the anterior uterine membrane, and the second-side endometrium is the posterior uterine membrane, or the first-side endometrium is the posterior uterine membrane, and the second-side endometrium is the anterior uterine membrane; The step of automatically connecting the first feature points one by one from the feature points at one end of the endometrium to the feature points at the other end of the endometrium according to the direction of the endometrium to form an endometrial boundary line of the endometrium includes: According to the direction of the endometrium, the characteristic points at one end of the first endometrium are automatically connected to the characteristic points at the other end one by one to form a boundary line of the first endometrium; automatically connecting characteristic points at one end of the second endometrium to characteristic points at the other end one by one according to the direction of the endometrium to form a boundary line of the second endometrium; The determining of at least the region between the endometrial boundary lines in the uterine ultrasound image as the region of interest includes: At least a region between the first endometrial boundary line and the second endometrial boundary line in the uterine ultrasound image is determined as the region of interest.

16. The method according to claim 14, characterized in that The first characteristic point of the endometrium in the uterine ultrasound image includes a characteristic point located on a first side of the endometrium, and the first side of the endometrium is the anterior uterine membrane or the posterior uterine membrane; The step of automatically connecting the first feature points one by one from the feature points at one end of the endometrium to the feature points at the other end of the endometrium according to the direction of the endometrium to form an endometrial boundary line of the endometrium includes: According to the direction of the endometrium, the characteristic points at one end of the first endometrium are automatically connected to the characteristic points at the other end one by one to form a boundary line of the first endometrium; A second intima boundary line is generated at a position close to a second intima according to the first intima boundary line, wherein the second intima and the first intima are intima on different sides.

17. The method according to claim 16, characterized in that Generating a second intimal boundary line at a position close to the second intimal boundary line according to the first intimal boundary line includes: The first intima boundary line is copied, and the ultrasound imaging device is moved toward the second intima to obtain the second intima boundary line.

18. The method according to claim 16, characterized in that The first feature point of the endometrium in the uterine ultrasound image also includes a feature point located on the second side endometrium; Generating a second intimal boundary line at a position close to the second intimal boundary line according to the first intimal boundary line includes: The first intima boundary line is copied and moved to coincide with at least one characteristic point of the second intima to obtain the second intima boundary line.

19. The method according to claim 15 or 18, characterized in that The determining of a first characteristic point of the endometrium in the uterine ultrasound image includes: determining characteristic points of a first side of the endometrium in the uterine ultrasound image; A point that is close to the second side endometastasis in the direction of a perpendicular line based on the characteristic point of the first side endometastasis and is at a second preset distance from the characteristic point of the first side endometastasis is used as the characteristic point of the second side endometastasis, or a point that is close to the second side endometastasis in the direction of a perpendicular line based on the boundary line generated from the characteristic point of the first side endometastasis and is at a third preset distance from the characteristic point of the first side endometastasis is used as the characteristic point of the second side endometastasis, and the perpendicular line passes through the characteristic point of the first side endometastasis.

20. The method according to any one of claims 14 to 18, characterized in that The region of interest further includes: A uterine fundus region is generated according to the feature points located at the uterine fundus, and / or a uterine cervix region is generated according to the feature points located at the uterine cervix.

21. The method according to claim 20, characterized in that When the uterine ultrasound image is a longitudinal section ultrasound image, the uterine fundus region is a circular region, and the cervical region is a rectangular region; When the uterine ultrasound image is a transverse ultrasound image, the uterine fundus region and the cervical region are both circular regions.

22. The method according to claim 21, characterized in that The circular area is tangent to the intimal boundary line at least at one location, and / or at least one vertex of the rectangular area is located on the intimal boundary line.

23. The method according to claim 20, characterized in that Generating a uterine fundus region according to the feature points located at the uterine fundus, and / or generating a cervical region according to the feature points located at the cervix, includes: generating the uterine fundus region according to the boundary line endpoint located at the uterine fundus on the endometrial boundary line in the uterine ultrasound image; The cervical region is generated according to the boundary line endpoint located at the cervix on the endometrial boundary line in the uterine ultrasound image.

24. A method for determining a region of interest in an ultrasound image, characterized in that: include: Acquiring a uterine ultrasound image, and displaying the uterine ultrasound image through a display interface of a display; Determine first feature points of the endometrium in the uterine ultrasound image, where the first feature points include feature points located at the cervix and feature points located at the fundus of the uterus; According to the direction of the endometrium, the characteristic points of the first side of the endometrium are automatically connected one by one from the characteristic points at one end to the characteristic points at the other end to form a boundary line of the first side of the endometrium; According to the direction of the endometrium, the characteristic points of the second side of the endometrium are automatically connected one by one from the characteristic points at the other end to the characteristic points at one end to form a boundary line of the second side of the endometrium; wherein the first endometrium is the anterior uterine membrane, and the second endometrium is the posterior uterine membrane, or, The first endometrium is the posterior uterine lining, and the second endometrium is the anterior uterine lining; determining, in the uterine ultrasound image, at least a region between the first endometrial boundary line and the second endometrial boundary line as the region of interest; The method further comprises: Identifying the boundary of the region where the endometrium is located, and determining the direction of the endometrium according to the boundary of the region where the endometrium is located; or The lateral endometrium of the endometrium is identified, and the direction of the endometrium is determined according to the direction of the lateral endometrium of the endometrium.

25. The method according to claim 24, characterized in that The feature points forming the boundary line of the second side endometaphase include: the feature points of the first feature points located on the second side endometaphase, and the points close to the second side endometaphase according to the perpendicular direction of the feature points of the first side endometaphase, and the distance from the feature points of the first side endometaphase to the feature points is a second preset distance.

26. The method according to claim 24 or 25, characterized in that The region of interest further includes: A uterine fundus region is generated according to the feature points located at the uterine fundus, and / or a uterine cervix region is generated according to the feature points located at the uterine cervix.

27. A method for determining a region of interest in an ultrasound image, characterized in that: include: Acquiring a uterine ultrasound image, and displaying the uterine ultrasound image through a display interface of a display; determining second feature points in the uterine cavity of the endometrium in the uterine ultrasound image, wherein the second feature points include feature points located at the cervix and feature points located at the fundus of the uterus; automatically connecting the second feature points including the feature points of the cervix and the feature points of the uterine fundus according to the direction of the endometrium to form a uterine cavity line of the endometrium; generating an anterior membrane boundary line and a posterior membrane boundary line based on the uterine cavity line; determining at least a region between the anterior membrane boundary line and the posterior membrane boundary line in the uterine ultrasound image as the region of interest; The method further comprises: Identifying the boundary of the region where the endometrium is located, and determining the direction of the endometrium according to the boundary of the region where the endometrium is located; or The lateral endometrium of the endometrium is identified, and the direction of the endometrium is determined according to the direction of the lateral endometrium of the endometrium.

28. The method according to claim 27, characterized in that The generating of the anterior membrane boundary line and the posterior membrane boundary line based on the uterine cavity line comprises: Moving the uterine cavity line toward the position of the first endometrium to obtain a first endometrial boundary line, wherein the first endometrium is the anterior uterine membrane or the posterior uterine membrane; The first side intima boundary line is copied and moved toward the position of the second side intima to obtain a second side intima boundary line, wherein the second side intima and the first side intima are intima on different sides.

29. The method according to claim 28, characterized in that The generating of the anterior membrane boundary line and the posterior membrane boundary line based on the uterine cavity line comprises: duplicating the uterine cavity line to obtain two uterine cavity lines; moving one of the two uterine cavity lines toward the position of the anterior uterine membrane to obtain the anterior membrane boundary line; The other of the two uterine cavity lines is moved toward the posterior uterine membrane to obtain the posterior membrane boundary line.

30. The method according to claim 29, wherein The generating of the anterior membrane boundary line and the posterior membrane boundary line based on the uterine cavity line comprises: determining the feature points of the anterior uterine membrane and the feature points of the posterior uterine membrane based on the uterine cavity line and the second feature points; The anterior uterine membrane boundary line is determined according to the feature points of the anterior uterine membrane, and the posterior uterine membrane boundary line is determined according to the feature points of the posterior uterine membrane.

31. The method according to claim 30, wherein The determining of the feature points of the anterior uterine membrane and the posterior uterine membrane based on the uterine cavity line and the second feature points includes: A point that is close to the preuterine membrane in the normal direction or the perpendicular direction of the uterine cavity line and is a third preset distance away from the second characteristic point is used as a characteristic point of the preuterine membrane; A point close to the posterior uterine membrane in the normal direction or the perpendicular direction of the curve corresponding to the uterine cavity line and with a distance from the second characteristic point being a fourth preset distance is used as a characteristic point of the posterior uterine membrane.

32. The method according to any one of claims 27 to 31, characterized in that The region of interest further includes: A fundus region is generated at one end of the anterior membrane boundary line and the posterior membrane boundary line close to the fundus of the uterus, and / or a cervix region is generated at one end close to the cervix of the uterus.

33. The method according to claim 32, characterized in that When the uterine ultrasound image is a longitudinal section ultrasound image, the uterine fundus region is a circular region, and the cervical region is a rectangular region; and / or When the uterine ultrasound image is a transverse ultrasound image, the uterine fundus region and the cervical region are both circular regions.

34. The method according to claim 33, wherein The circular area is tangent to the front membrane boundary line or the back membrane boundary line at least at one point, and / or At least one vertex of the rectangular region is located on the anterior membrane boundary line or the posterior membrane boundary line.

35. The method according to claim 32, wherein Generating a uterine fundus region according to the feature points located at the uterine fundus, and / or generating a cervical region according to the feature points located at the cervix, includes: Generating the uterine fundus region according to the boundary line endpoint of the anterior membrane boundary line located at the uterine fundus and the boundary endpoint of the posterior membrane boundary line located at the uterine fundus in the uterine ultrasound image; and / or The uterine fundus region is generated according to the boundary line endpoint of the anterior membrane boundary line located on the cervix and the boundary line endpoint of the posterior membrane boundary line located on the cervix in the uterine ultrasound image.

36. A method for determining a region of interest in an ultrasound image, characterized in that: include: Acquiring a uterine ultrasound image, and displaying the uterine ultrasound image through a display interface of a display; determining second feature points in the uterine cavity of the endometrium in the uterine ultrasound image, wherein the second feature points include feature points located at the cervix and feature points located at the fundus of the uterus; automatically connecting the second feature points including the feature points of the cervix and the feature points of the uterine fundus according to the direction of the endometrium to form a uterine cavity line of the endometrium; generating an anterior membrane boundary line and / or a posterior membrane boundary line based on the uterine cavity line; determining, in the uterine ultrasound image, a region between at least any two of the anterior membrane boundary line, the posterior membrane boundary line, and the uterine cavity line as the region of interest; The method further comprises: Identifying the boundary of the region where the endometrium is located, and determining the direction of the endometrium according to the boundary of the region where the endometrium is located; or The lateral endometrium of the endometrium is identified, and the direction of the endometrium is determined according to the direction of the lateral endometrium of the endometrium.

37. A method for determining a region of interest in an ultrasound image, characterized in that: include: Acquiring a uterine ultrasound image, and displaying the uterine ultrasound image through a display interface of a display; Determine first feature points of the endometrium in the uterine ultrasound image, where the first feature points include feature points located at the cervix and feature points located at the fundus of the uterus; automatically connecting the first feature points including the feature points of the cervix and the feature points of the fundus according to the direction of the endometrium to form an endometrial boundary line of the endometrium; generating a uterine cavity line based on an endometrial boundary line of the endometrium; determining, in the uterine ultrasound image, at least a region between the endometrial boundary line and the uterine cavity line as the region of interest; The method further comprises: Identifying the boundary of the region where the endometrium is located, and determining the direction of the endometrium according to the boundary of the region where the endometrium is located; or The lateral endometrium of the endometrium is identified, and the direction of the endometrium is determined according to the direction of the lateral endometrium of the endometrium.

38. A method for determining a region of interest in an ultrasound image, characterized in that: include: Acquiring a uterine ultrasound image, and displaying the uterine ultrasound image through a display interface of a display; Determine first feature points of a first side of the endometrium in the uterine ultrasound image, wherein the first feature points include feature points located at the cervix and feature points located at the fundus of the uterus; wherein the first side of the endometrium includes anterior uterine membrane or posterior uterine membrane of the endometrium; automatically connecting the first feature points including the feature points of the cervix and the feature points of the fundus according to the direction of the endometrium to form a first boundary line of the endometrium on the first side; generating a second boundary line based on the first boundary line at a position away from the first endometrium and close to the myometrium; determining at least a region between the first boundary line and the second boundary line in the uterine ultrasound image as the region of interest; The method further comprises: Identifying the boundary of the region where the endometrium is located, and determining the direction of the endometrium according to the boundary of the region where the endometrium is located; or The lateral endometrium of the endometrium is identified, and the direction of the endometrium is determined according to the direction of the lateral endometrium of the endometrium.

39. A method for determining a region of interest in an ultrasound image, characterized in that: include: Acquiring a uterine ultrasound image, and displaying the uterine ultrasound image through a display interface of a display; determining a third feature point of the endometrium in the uterine ultrasound image, wherein the third feature point includes a feature point located at the cervix and a feature point located at the fundus of the uterus; According to the direction of the endometrium, the third characteristic points are automatically connected one by one along the shortest path to form an endometrial boundary line of the endometrium; determining at least a region between the endometrial boundary lines in the uterine ultrasound image as the region of interest; The method further comprises: Identifying the boundary of the region where the endometrium is located, and determining the direction of the endometrium according to the boundary of the region where the endometrium is located; or The lateral endometrium of the endometrium is identified, and the direction of the endometrium is determined according to the direction of the lateral endometrium of the endometrium.

40. The method according to claim 39, wherein According to the direction of the endometrium, the third characteristic points are automatically connected one by one along the shortest path to form the endometrial boundary line of the endometrium, including: Selecting a starting point from the third characteristic points; The endometrial boundary line of the endometrium is formed by connecting the starting points one by one in a counterclockwise / clockwise direction and along the shortest path.

41. The method according to claim 40, wherein The starting point is a feature point located on the cervix or the fundus of the uterus among the third feature points.

42. An ultrasonic imaging device, characterized in that: include: Probe; a transmitting circuit, wherein the transmitting circuit excites the probe to transmit ultrasonic waves toward the uterus; a receiving circuit, wherein the receiving circuit controls the probe to receive the ultrasonic echo to obtain an ultrasonic echo signal; Display, providing a display interface; The ultrasonic imaging device processes the ultrasonic echo signal to obtain a uterine ultrasonic image; and performs the steps of the method for determining a region of interest in an ultrasonic image according to any one of claims 1 to 41 to determine a region of interest in the uterine ultrasonic image; The ultrasonic imaging device is further used to extract and process the ultrasonic echo signal of the region of interest to obtain the peristaltic motion parameters of the region of interest; and to display a graph showing the peristaltic motion parameters of the region of interest changing over time through the display interface of the display.

43. A computer-readable storage medium, characterized in that The computer-readable storage medium stores a computer program, which, when executed by a processor, causes the processor to implement: The steps of the method for determining a region of interest in an ultrasound image according to any one of claims 1 to 41.

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