aneurysm closure device

Abstract

This invention relates to an aneurysm closure device, comprising a closure body and a support body. The closure body includes a main body portion and an inner cavity, the main body portion having a distal end and a proximal end; the support body is located within the inner cavity and also has a distal end and a proximal end; at least one of the distal end and proximal end of the main body portion has a constricted portion, the constricted portion being recessed into the corresponding end of the main body portion; and the constricted portion is connected to the corresponding end of the support body. Because at least one of the proximal end and distal end of the main body portion has a constricted portion, and the constricted portion is recessed into the corresponding end of the main body portion, when the aneurysm closure device is located on an aneurysm, the constricted portion will not protrude beyond the corresponding end of the main body portion, reducing the risk of aneurysm rupture. Since the constricted portion is connected to the corresponding end of the support body, the constricted portion can be constrained by the corresponding end of the support body, further reducing the risk of aneurysm rupture.

Description

Technical Field

[0001] This invention relates to the field of medical device technology, and in particular to aneurysm closure devices. Background Technology

[0002] Intracranial aneurysms are abnormal bulges formed by the gradual expansion of intracranial arterial walls due to congenital abnormalities or acquired injuries, under the influence of hemodynamic load and other factors. With the rapid development of interventional treatment techniques for intracranial aneurysms over the past 30 years, new interventional devices for aneurysms have continuously emerged, evolving from coils to flow diverting devices and then to intra-aneurysmal occlusion devices.

[0003] Coil embolization is a treatment technique that involves embolizing coils within an aneurysm to seal it. This alters the blood flow within the aneurysm, reducing the impact of blood flow on the aneurysm wall and thus decreasing the risk of aneurysm enlargement. However, to minimize the risk of aneurysm recurrence, a certain number of coils often need to be embolized to achieve a sufficient embolization rate for optimal therapeutic results. On one hand, the surgeon needs to release coils multiple times to release a sufficient number, leading to a prolonged procedure. On the other hand, embolizing too many coils can sometimes result in over-embolization, potentially increasing the risk of aneurysm rupture. Therefore, coil embolization requires surgeons with sufficient skill and experience. Furthermore, coil embolization is more suitable for narrow-necked aneurysms, while for wide-necked aneurysms, various auxiliary techniques (such as dual-microcatheter techniques, balloon-assisted embolization, and stent-assisted techniques) are needed to expand the indications for coil embolization. These auxiliary techniques also require surgeons with considerable clinical experience.

[0004] Flow diverters are endovascular interventional devices that guide blood flow within a blood vessel, primarily by preventing further blood flow into the aneurysm, thus achieving aneurysm closure. Flow diverters overcome the limitations of coil therapy for wide-necked aneurysms. However, as endovascular interventional devices, to prevent thrombosis, patients require lifelong dual antiplatelet therapy. Antiplatelet therapy can affect the patient's coagulation function, thereby increasing the risk of postoperative bleeding complications.

[0005] Intraacular occlusion devices are the latest type of aneurysm treatment equipment. They can be deployed into the aneurysm in a single procedure to seal it. The operation is short, requires less experience from the surgeon, and patients do not need long-term dual antiplatelet therapy after the procedure. However, most current intraaneurysm occlusion devices are made of braided mesh tubing. When sealing the ends of the braided mesh, rivet points are left, which can easily lead to aneurysm rupture. Furthermore, current intraaneurysm occlusion devices are prone to deformation and displacement after being subjected to blood flow impact.

[0006] In summary, traditional intraneural occlusion devices are prone to causing aneurysm rupture and are susceptible to deformation and displacement after being subjected to blood flow impact. Summary of the Invention

[0007] Therefore, it is necessary to provide an aneurysm closure device that is less prone to aneurysm rupture and deformation and displacement after being subjected to blood flow impact, in order to address the problems of traditional intraneural closure devices.

[0008] One embodiment of this application provides an aneurysm closure device, which includes a closure body and a support body. The aneurysm closure device has a compressed state for being transported and an expanded state for closure of the aneurysm. The closure body and the support body of the aneurysm closure device switch between the compressed state and the expanded state.

[0009] When the aneurysm occlusion device is in the deployed state, the occlusion body has a woven mesh structure, the occlusion body includes a main body and an inner cavity, the main body has a distal end and a proximal end; the support body is located in the inner cavity, and the support body also has a distal end and a proximal end; at least one of the distal end and the proximal end of the main body has a constricted portion, the constricted portion being recessed into the corresponding end of the main body; and the constricted portion is connected to the corresponding end of the support body.

[0010] In one embodiment, the distal end of the main body portion has the tapered portion; and / or, the proximal end of the main body portion has the tapered portion.

[0011] In one embodiment, the closing portion has a first end and a second end, the first end being continuous with the main body portion, the closing portion gradually converging from the first end to the second end, and the second end facing the interior of the sealing body.

[0012] In one embodiment, the aneurysm occlusion device further includes a connecting ring corresponding to the converging portion. The converging portion has a first end and a second end. The first end is continuous with the main body portion. The converging portion gradually converges from the first end to the second end, and the second end converges to the corresponding connecting ring.

[0013] In one embodiment, the plugging body and / or the support body are made of shape memory material or elastic material, and the distal and proximal ends of the support body are used to support the plugging body, respectively.

[0014] In one embodiment, when the aneurysm occlusion device is in the deployed state, the outer diameter of the occlusion body gradually increases and then gradually decreases along the direction from distal to proximal; or,

[0015] When the aneurysm occlusion device is in the deployed state, the occlusion body has a cylindrical structure.

[0016] In one embodiment, the maximum outer diameter of the sealing body is greater than or equal to the maximum outer diameter of the support body.

[0017] In one embodiment, when the aneurysm occlusion device is in the deployed state, the support body includes a tubular body that extends in a spiral direction from the distal end to the proximal end.

[0018] In one embodiment, the tubular body is a woven mesh structure or a laser-engraved mesh structure; or

[0019] The tubular body is formed by spirally winding spring wire along the length of the tubular body.

[0020] In one embodiment, the distal end of the tubular body has a tapered structure; and / or, the proximal end of the tubular body has a tapered structure.

[0021] In one embodiment, the support is a spring coil, which includes a tubular body. The tubular body is formed by spirally winding spring wire along the length of the tubular body. When the aneurysm occlusion device is in the deployed state, the spring coil forms a basket.

[0022] The aforementioned aneurysm closure device has a constricted portion at least one of its proximal and distal ends in the main body. This constricted portion is recessed into the corresponding end of the main body, ensuring that when the aneurysm closure device is located on an aneurysm, the constricted portion does not extend beyond the corresponding end of the main body, thus reducing the risk of aneurysm rupture. Because the constricted portion is connected to the corresponding end of the support body, its position is constrained by the corresponding end of the support body, preventing it from extending beyond the corresponding end of the main body due to the impact of blood flow, further reducing the risk of aneurysm rupture. Furthermore, the support body is located within the lumen, with its distal and proximal ends supporting the closure body. Therefore, when blood flows through the aneurysm, the support of the support body ensures that the closure body does not deform or shift due to blood impact, maximizing the closure effect and reducing or avoiding the risk of aneurysm recurrence. Attached Figure Description

[0023] Figure 1 This is a schematic diagram of the structure of an aneurysm occlusion device according to one embodiment;

[0024] Figure 2 for Figure 1 A schematic diagram showing the aneurysm closure device located inside the aneurysm.

[0025] Figure 3 This is a schematic diagram of the aneurysm closure device according to another embodiment;

[0026] Figure 4 This is a schematic diagram of the structure of an aneurysm closure device according to another embodiment;

[0027] Figures 5 to 7 This is a schematic diagram of the aneurysm closure device in some embodiments.

[0028] Explanation of icon numbers:

[0029] 11. Blood vessel; 12. Aneurysm; 13. Neck of aneurysm;

[0030] Blocking body 110; inner cavity 101; main body portion 111; distal end 111c of main body portion 111; proximal end 111d of main body portion 111; closing portion 112; first end 112a; second end 112b

[0031] Support body 120;

[0032] Connecting ring 130. Detailed Implementation

[0033] To make the above-mentioned objects, features, and advantages of the present invention more apparent and understandable, specific embodiments of the present invention will be described in detail below with reference to the accompanying drawings. Many specific details are set forth in the following description to provide a thorough understanding of the present invention. However, the present invention can be practiced in many other ways different from those described herein, and those skilled in the art can make similar modifications without departing from the spirit of the present invention. Therefore, the present invention is not limited to the specific embodiments disclosed below.

[0034] In the description of this invention, it should be understood that the terms "center," "longitudinal," "lateral," "length," "width," "thickness," "upper," "lower," "front," "rear," "left," "right," "vertical," "horizontal," "top," "bottom," "inner," "outer," "clockwise," "counterclockwise," "axial," "radial," and "circumferential" indicate the orientation or positional relationship based on the orientation or positional relationship shown in the accompanying drawings. They are used only for the convenience of describing this invention and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation. Therefore, they should not be construed as limitations on this invention.

[0035] Furthermore, the terms "first" and "second" are used for descriptive purposes only and should not be construed as indicating or implying relative importance or implicitly specifying the number of technical features indicated. Thus, a feature defined as "first" or "second" may explicitly or implicitly include at least one of that feature. In the description of this invention, "a plurality of" means at least two, such as two, three, etc., unless otherwise explicitly specified.

[0036] In this invention, unless otherwise explicitly specified and limited, the terms "installation," "connection," "linking," and "fixing," etc., should be interpreted broadly. For example, they can refer to a fixed connection, a detachable connection, or an integral part; they can refer to a mechanical connection or an electrical connection; they can refer to a direct connection or an indirect connection through an intermediate medium; they can refer to the internal communication of two components or the interaction between two components, unless otherwise explicitly limited. Those skilled in the art can understand the specific meaning of the above terms in this invention according to the specific circumstances.

[0037] In this invention, unless otherwise explicitly specified and limited, "above" or "below" the second feature can mean that the first feature is in direct contact with the second feature, or that the first feature is in indirect contact with the second feature through an intermediate medium. Furthermore, "above," "over," and "on top" of the second feature can mean that the first feature is directly above or diagonally above the second feature, or simply that the first feature is at a higher horizontal level than the second feature. "Below," "below," and "under" the second feature can mean that the first feature is directly below or diagonally below the second feature, or simply that the first feature is at a lower horizontal level than the second feature.

[0038] It should be noted that when an element is referred to as being "fixed to" or "set on" another element, it can be directly on the other element or there may be an intervening element. When an element is considered to be "connected to" another element, it can be directly connected to the other element or there may be an intervening element. The terms "vertical," "horizontal," "upper," "lower," "left," "right," and similar expressions used herein are for illustrative purposes only and do not represent the only possible implementation.

[0039] Please refer to Figure 1 This application provides an embodiment of an aneurysm occlusion device. See also... Figure 2Aneurysm 12 protrudes outward from the side wall of the patient's blood vessel 11. When the aneurysm closure device is used to treat the patient's aneurysm 12, it is placed inside the aneurysm 12, with one end of the aneurysm closure device close to the aneurysm top and the other end close to the aneurysm neck. For ease of explanation, the terms "proximal" and "distal" are used below. The proximal end refers to the end that is relatively closer to the surgeon's hand during the aneurysm treatment surgery, and the distal end refers to the end that is relatively farther away from the surgeon's hand during the aneurysm treatment surgery.

[0040] The aneurysm closure device includes a closure body 110 and a support body 120. The aneurysm closure device has a compressed state for delivery and an expanded state for closure of the aneurysm 12. The aneurysm closure device can switch between the compressed state and the expanded state by deformation of the closure body 110 and the support body 120.

[0041] When the aneurysm closure device is used to treat a patient's aneurysm 12, it can be delivered into the patient's aneurysm 12 using a microcatheter (not shown) and a push rod (not shown). Specifically, by compressing and deforming the closure body 110 and the support body 120 respectively, the aneurysm closure device is switched from an unfolded state to a compressed state, which allows it to be compressed into an elongated structure for easy insertion into the microcatheter. A delivery channel is established within the patient's blood vessel 11 through the microcatheter, and then the push rod pushes the aneurysm closure device out of the microcatheter's outlet, thereby releasing the aneurysm closure device into the aneurysm 12.

[0042] like Figure 2 As shown, when the aneurysm closure device is released into the aneurysm 12, it is no longer restricted by the microcatheter, thus switching from a compressed state to an extended state. In the extended state, the closure body 110 has a woven mesh structure. The closure body 110 includes a main body 111 and an inner lumen 101. The inner lumen 101 is located within the main body 101, allowing the closure body 110 to have a certain expansion volume. This allows the closure body 110 to more fully occupy the space inside the aneurysm 12, effectively sealing the aneurysm 12. It should be noted that when the aneurysm closure device switches from the extended state to the compressed state, the volume of the inner lumen 101 decreases.

[0043] Specifically, the sealing body 110 is a woven mesh structure made of woven wire. Therefore, it is necessary to bundle and fix the woven wires at the ends of the main body 111 together to form a closing portion 112, that is, the woven wires of the main body 111 and the woven wires of the closing portion 112 are continuous and integral. In this embodiment, the distal end 111c and the proximal end 111d of the main body 111 each have a closing portion 112, that is, the distal end 111c of the main body 111 is closed by its corresponding closing portion 112, and the proximal end 111d of the main body 111 is closed by its corresponding closing portion 112.

[0044] The tapered portion 112 is recessed at the corresponding end of the main body portion 111. In this embodiment, the tapered portion 112 at the distal end 111c of the main body portion 111 is recessed at the distal end 111c of the main body portion 111, and the tapered portion 112 at the proximal end 111d of the main body portion 111 is recessed at the proximal end 111d of the main body portion 111. For example... Figure 2 As shown, since the constricted portion 112 is recessed at the corresponding end of the main body portion 111, when the aneurysm sealing device is located on the aneurysm 12, the constricted portion 12 will not extend beyond the corresponding end of the main body portion 111, thereby making it less likely for the constricted portion 12 to puncture the aneurysm 12 and reducing the risk of the aneurysm 12 rupturing.

[0045] The support 120 is located within the inner cavity 101. The constricted portion 112 is connected to the corresponding end of the support 120. In this embodiment, the constricted portion 112 at the distal end 111c of the main body 111 is connected to the distal end of the support 120, and the constricted portion 112 at the proximal end 111d of the main body 111 is connected to the proximal end of the support 120. Thus, the constricted portion 112 at the distal end 111c of the main body 111 is constrained by the distal end of the support 120, and the constricted portion 112 at the proximal end 111d of the main body 111 is constrained by the proximal end of the support 120. This effectively constrains the position of the constricted portion 112, preventing it from extending beyond the corresponding end of the main body 111 due to the impact of blood flow. Therefore, the risk of aneurysm 12 rupture is further reduced.

[0046] Furthermore, since the constricted portion 112 at the distal end 111c of the main body 111 is connected to the distal end of the support 120, the distal end of the support 120 can support the constricted portion 112 at the distal end 111c of the main body 111, thereby providing support for the distal end of the occlusion body 110. Similarly, since the constricted portion 112 at the proximal end 111d of the main body 111 is connected to the proximal end of the support 120, the proximal end of the support 120 can support the constricted portion 112 at the proximal end 111d of the main body 111, thereby providing support for the proximal end of the occlusion body 110. Therefore, when blood flows through the aneurysm 12 in the blood vessel 11, the support of the support 120 can ensure that the occlusion body 110 is not deformed or displaced due to the impact of blood flow, thus maximizing the occlusion effect and reducing or avoiding the risk of aneurysm 12 recurrence.

[0047] In other embodiments, the closing portion may be a single element. For example, the main body portion may have a closing portion at its distal end but not at its proximal end. Thus, the closing portion at the distal end of the main body portion is recessed within the distal end of the main body portion, and this closing portion at the distal end of the main body portion connects to the distal end of the support body. In this case, the proximal end of the support body can be directly connected to the proximal end of the main body portion. Similarly, in another embodiment, the main body portion may have a closing portion at its proximal end but not at its distal end. Thus, the closing portion at the proximal end of the main body portion is recessed within the proximal end of the main body portion, and this closing portion at the proximal end of the main body portion connects to the proximal end of the support body. In this case, the distal end of the support body can be directly connected to the distal end of the main body portion.

[0048] In the aforementioned aneurysm closure device, at least one end of the proximal and distal ends of the main body 111 has a constricted portion 112. The constricted portion 112 is recessed into the corresponding end of the main body 111, so that when the aneurysm closure device is located on the aneurysm 12, the constricted portion 112 will not protrude beyond the corresponding end of the main body 111, thereby reducing the risk of aneurysm 12 rupture. Since the constricted portion 112 is connected to the corresponding end of the support 120, the position of the constricted portion 112 can be constrained by the corresponding end of the support 120, thereby preventing the constricted portion 112 from protruding beyond the corresponding end of the main body 111 due to the impact force of blood, further reducing the risk of aneurysm 12 rupture. Furthermore, since the support body 120 is located within the lumen 101, the distal and proximal ends of the support body 120 can support the occlusion body 110 respectively. Therefore, when blood in the blood vessel 11 flows through the aneurysm 12, the support of the support body 120 can ensure that the occlusion body 110 is not deformed or displaced due to the impact of blood, so as to ensure the occlusion effect as much as possible and reduce or avoid the risk of recurrence of the aneurysm 12.

[0049] Please refer to Figure 1In one embodiment, the closing portion 112 has a first end 112a and a second end 112b. The first end 112a is continuous with the main body portion 111. When weaving the sealing body 110, when a portion of the filament is woven to the end of the main body portion 111, the closing portion 112 can be woven continuously using the remaining filament that is continuous with that portion of the filament, that is, the closing portion 112 can be woven starting from the first end 112a. When weaving the closing portion 112, we can weave from the first end 112a to the second end 112b. The closing portion 112 gradually converges from the first end 112a to the second end 112b, that is, the diameter of the closing portion 112 gradually decreases, so that the filaments of the closing portion 112 gather and are fixed together at the second end 112b. As can be seen, the second end 112b is the gathering end of the filament of the closing part 112. Therefore, when the closing part 112 is connected to the corresponding end of the support body 120, it is connected to the corresponding end of the support body 120 through the second end 112b, which facilitates the connection between the closing part 112 and the support body 120.

[0050] like Figure 1 As shown, in one embodiment, the second end 112b faces the interior of the sealing body 110, that is, the interior of the inner cavity 101. It can be understood that since the converging portion 112 gradually converges from the first end 112a to the second end 112b, the second end 112b is sharper than the first end 112a, forming a pointed tip. Therefore, in this embodiment, the second end 112b faces the interior of the sealing body 110, i.e., the pointed tip faces inward, thereby further preventing the second end 112b from puncturing the aneurysm and further reducing the risk of aneurysm 12 rupture.

[0051] In other embodiments, the second end of the closed portion may also face the outside of the sealing body (i.e., the outside of the inner cavity). As long as the closed portion is recessed into the corresponding end of the main body, the second end of the closed portion will not extend beyond the corresponding end of the main body, thus making it difficult to puncture the aneurysm and reducing the risk of aneurysm rupture to a certain extent.

[0052] Please refer to Figure 1 and Figure 2 In one embodiment, the aneurysm closure device further includes a connecting ring 130 corresponding to the closing portion 112. The second end 112b converges to the corresponding connecting ring 130. Specifically, the filament of the closing portion 112 can be bonded to the connecting ring 130 at the second end 112b using an adhesive (including but not limited to UV adhesive, epoxy adhesive, etc.), or the filament of the closing portion 112 can be fixed to the connecting ring 130 at the second end 112b by welding.

[0053] In one embodiment, the occlusion body 110 is made of a shape memory material, enabling it to deform and facilitate switching between a compressed and deployed state of the aneurysm occlusion device. Specifically, the shape memory material can be a metal with shape memory function, such as a nickel-titanium (Ni-Ti) alloy, a nickel-titanium-cobalt (Ni-Ti-Co) alloy, or a bilayer composite metal wire (Ni-Ti@Pt). The shape memory material can also be a polymer material with shape memory function, such as poly(p-dioxanone) (PDO) or (lactide-ε-caprolactone) copolymer (PLC).

[0054] In one embodiment, the woven mesh structure of the sealing body 110 uses filaments with a diameter between 0.0008 inches and 0.002 inches, and the number of braids is between 48 and 144.

[0055] In one embodiment, when the aneurysm occlusion device is in the deployed state, it extends from the distal end to the proximal end (i.e., Figure 2 In the YY' direction, the outer diameter of the occlusion body 110 gradually increases and then gradually decreases, meaning the occlusion body 110 has a shape that gradually thickens from the distal end to the middle and gradually tapers from the middle to the proximal end. This shape of the occlusion body 110 can better match the shape of the aneurysm 12, resulting in a better occlusion effect. Furthermore, because the occlusion body 110 gradually thickens from the distal end to the middle, the middle portion of the occlusion body 110 is thicker, which helps to prevent the occlusion body 110 from shifting out of the aneurysm 12 from the neck opening 13. Therefore, it ensures the stability of the aneurysm occlusion device during the treatment of the aneurysm 12.

[0056] like Figure 1 As shown, in this embodiment, the sealing body 110 is spherical in shape.

[0057] In other embodiments, the sealing body may also take the form of other shapes such as an ellipsoid.

[0058] In one embodiment, the support 120 is made of a shape memory material, enabling it to deform and facilitate switching between a compressed and deployed state of the aneurysm closure device. Specifically, the shape memory material can be a metal with shape memory function, such as a nickel-titanium (Ni-Ti) alloy, a nickel-titanium-cobalt (Ni-Ti-Co) alloy, or a bilayer composite metal wire (Ni-Ti@Pt). The shape memory material can also be a polymer material with shape memory function, such as poly(p-dioxanone) (PDO) or (lactide-ε-caprolactone) copolymer (PLC).

[0059] refer to Figure 1 and Figure 2In one embodiment, when the aneurysm occlusion device is in the deployed state, the support 120 includes a tubular body that extends in a helical direction from the distal end to the proximal end. Thus, the tubular body can be approximated as a helical spring structure with the axis of the helical spring structure along the direction (YY') from the distal end to the proximal end. Furthermore, the tubular body (i.e., the support 120) can provide reliable elastic force to the distal and proximal ends of the occlusion body 110 in order to reliably support the occlusion body 110.

[0060] refer to Figure 1 and Figure 2 In one embodiment, along the direction from the distal end to the proximal end (YY'), the outer diameter of the tubular body gradually decreases from the middle to both ends. That is, the diameter of the tubular body gradually increases from the distal end to the middle and gradually decreases from the middle to the proximal end.

[0061] When the aneurysm occlusion device switches from the deployed state to the compressed state, the tubular body is thinner at both ends and thicker in the middle. This facilitates the insertion of the end of the aneurysm occlusion device into the microcatheter, allowing the thicker middle portion of the device to be gradually pushed into the microcatheter by the push rod. When the aneurysm occlusion device is pushed out of the microcatheter via the push rod, the thinner end of the device allows it to exit the microcatheter first, facilitating the gradual exit of the thicker middle portion by the push rod.

[0062] In other embodiments, the support is not limited to a tubular shape, but may be other shapes, and there is no limitation thereto.

[0063] In one embodiment, the tubular body described above adopts a woven mesh structure, that is, it is woven from filaments. Specifically, the diameter of the filaments used in the woven mesh structure is between 0.0008 inches and 0.002 inches, and the number of braids is between 48 and 144.

[0064] In other embodiments, the tubular body described above can also be a laser-engraved mesh structure formed by laser engraving.

[0065] In one embodiment, the tubular body is a woven mesh structure made of filaments. Therefore, the ends of the filaments need to be bundled and fixed together for closing. In this embodiment, the distal end of the tubular body has a closing structure. Therefore, the filaments at the distal end of the tubular body are bundled and fixed together to form a connection point, which facilitates the connection between the distal end of the tubular body (i.e., the distal end of the support 120) and the closing portion 112 at the distal end of the main body 111, or facilitates the direct connection between the distal end of the tubular body (i.e., the distal end of the support) and the distal end of the sealing body.

[0066] In one embodiment, the tubular body is a woven mesh structure made of filaments. Therefore, the ends of the individual filaments need to be bundled and fixed together for closing. In this embodiment, the proximal end of the tubular body has a closing structure. Therefore, the filaments at the proximal end of the tubular body are bundled and fixed together to form a connection point, thereby facilitating the connection between the proximal end of the tubular body (i.e., the proximal end of the support 120) and the closing portion 112 at the proximal end of the main body 111, or facilitating the direct connection between the proximal end of the tubular body (i.e., the proximal end of the support) and the proximal end of the sealing body.

[0067] In one embodiment, the maximum outer diameter of the sealing body 110 is greater than or equal to the maximum outer diameter of the support 120, thereby ensuring that the inner cavity 101 of the sealing body 110 can accommodate the support 120.

[0068] Specifically, in this embodiment, due to the direction from the distal end to the proximal end (i.e. Figure 1 In the YY' direction, the outer diameter of the occlusion body 110 first gradually increases and then gradually decreases. Therefore, the maximum outer diameter of the occlusion body 110 is located approximately at the midpoint of the occlusion body 110 in the direction from the distal end to the proximal end (YY'). Since the tubular body of the support 120 extends in a helical direction, in this embodiment, the outer diameter of the support 120 refers to the helical outer diameter of the tubular body (not the diameter of the tubular body itself). Therefore, the maximum outer diameter of the support 120 is the maximum helical outer diameter of the tubular body. Because the maximum outer diameter of the support 120 is not greater than the maximum outer diameter of the occlusion body 110, excessive compression of the aneurysm 12 by the support 120 on the sidewall can be prevented, thereby reducing the risk of aneurysm 12 rupture.

[0069] In one embodiment, the maximum outer diameter of the sealing body 110 is between 3 mm and 25 mm, and the maximum outer diameter of the support body 120 is between 3 mm and 25 mm.

[0070] Please refer to Figure 3 Another embodiment of this application provides an aneurysm closure device. This aneurysm closure device has a basically the same structure as the aneurysm closure device of any of the above embodiments, and the similarities will not be repeated. The differences between this embodiment and the previous one will be the focus of the description below.

[0071] In this embodiment, the tubular body is formed by spirally winding spring wire along its length. Specifically, the support 120 is prepared by spirally winding spring wire around a first mandrel along its axial direction to form the tubular body; then, the tubular body is spirally wound around a second mandrel along its axial direction and shaped, so that the shaped tubular body extends spirally from the distal end to the proximal end. When the aneurysm occlusion device is in a compressed state, the shaped tubular body can be stretched to facilitate insertion into the microcatheter. When the support 120 is released from the microcatheter, it naturally returns to the shape of the shaped tubular body. In some embodiments, the second mandrel can be cylindrical or a regular / irregular columnar body that is thinner at both ends and thicker in the center. The maximum outer diameter of the columnar body is 1 / 2 to 1 / 2 of the maximum outer diameter of the occlusion body.

[0072] In this embodiment, the diameter of the spring wire used to wind the tubular body is between 0.000001 inches and 0.0008 inches. The spring wire used to wind the tubular body is made of metal wire, specifically, the material of the metal wire includes, but is not limited to, platinum (Pt), tungsten (W), and platinum-tungsten alloy (Pt-W).

[0073] Please refer to Figure 4 Another embodiment of this application provides an aneurysm closure device. This aneurysm closure device has a basically the same structure as the aneurysm closure device of any of the above embodiments, and the similarities will not be repeated. The differences between this embodiment and the previous one will be the focus of the description below.

[0074] In this embodiment, the support 120 is a spring coil. The spring coil includes a tubular body. This tubular body is formed by spirally winding spring wire along the length of the tubular body. Figure 4 When the aneurysm closure device is in the deployed state, the spring coil forms a basket shape. This spring coil is prepared by spirally winding spring wire around a mandrel along its axial direction to form a tubular body; this tubular body is then wound onto a mold according to a predetermined shape (i.e., the shape of the spring coil when in the basket shape) and subjected to a shaping process to form the basket-shaped spring coil. When the aneurysm closure device is in the compressed state, the basket-shaped spring coil can be compressed, facilitating its insertion into the microcatheter. When the support 120 (i.e., the spring coil) is released from the microcatheter, it naturally returns to the shape of the basket-shaped spring coil.

[0075] The structure of the spring coiled into a basket can be a hexahedral structure, etc. For details, please refer to the existing technology, which will not be elaborated here.

[0076] In this embodiment, the diameter of the spring wire used to wind the spring coil is between 0.000001 inches and 0.0008 inches. The spring wire used to wind the spring coil is a metal wire, specifically, the material of the metal wire includes, but is not limited to, platinum (Pt), tungsten (W), and platinum-tungsten alloy (Pt-W).

[0077] Please refer to Figure 4 In this embodiment, since the support body 120 is a spring coil, the maximum outer diameter of the support body 120 is the maximum outer diameter of the spring coil when it is in a basket.

[0078] Please refer to Figures 5 to 7 The aneurysm closure device of some other embodiments of this application has a structure that is basically the same as the aneurysm closure device of any of the above embodiments, and the similarities will not be repeated. The following focuses on the differences between the aneurysm closure device of this embodiment.

[0079] Figures 5 to 7 In the embodiment shown, when the aneurysm occlusion device is in the deployed state, the occlusion body 110 has a cylindrical structure, specifically, it can be a cylinder, prism, elliptical cylinder, etc.

[0080] In this embodiment, the axial height of the cylindrical structure of the sealing body 110 is between 3mm and 25mm.

[0081] Figure 5 The support 120 of the embodiment shown is Figure 1 The support 120 in the illustrated embodiment has the same structure. Figure 6 The support 120 of the embodiment shown is Figure 3 The support 120 in the illustrated embodiment has the same structure. Figure 7 The support 120 of the embodiment shown is Figure 4 The support 120 in the illustrated embodiment has the same structure.

[0082] The technical features of the above embodiments can be combined in any way. For the sake of brevity, not all possible combinations of the technical features in the above embodiments are described. However, as long as there is no contradiction in the combination of these technical features, they should be considered to be within the scope of this specification.

[0083] The embodiments described above are merely illustrative of several implementations of the present invention, and while the descriptions are relatively specific and detailed, they should not be construed as limiting the scope of the invention patent. It should be noted that those skilled in the art can make various modifications and improvements without departing from the concept of the present invention, and these all fall within the protection scope of the present invention. Therefore, the protection scope of this invention patent should be determined by the appended claims.

Claims

1. An aneurysm occlusion device, characterized in that, The aneurysm closure device includes a closure body and a support body. The aneurysm closure device has a compressed state for being transported and an expanded state for closure of the aneurysm. The closure body and the support body of the aneurysm closure device switch between the compressed state and the expanded state. When the aneurysm occlusion device is in the deployed state, the occlusion body has a woven mesh structure, the occlusion body includes a main body and an inner cavity, the main body has a distal end and a proximal end; the support body is located in the inner cavity, and the support body also has a distal end and a proximal end; at least one of the distal end and the proximal end of the main body has a constricted portion, the constricted portion being recessed into the corresponding end of the main body; and the constricted portion is connected to the corresponding end of the support body; The closing portion has a first end and a second end. The first end is continuous with the main body portion. The closing portion gradually converges from the first end to the second end. The filaments of the closing portion gather and are fixed together at the second end. The support body includes a tubular body with a woven mesh structure. When the aneurysm occlusion device is in the deployed state, the tubular body extends in a spiral direction from the distal end to the proximal end. Alternatively, the support body is a spring coil, and when the aneurysm occlusion device is in the deployed state, the spring coil forms a basket.

2. The aneurysm occlusion device according to claim 1, characterized in that, The distal end of the main body portion has the tapered portion; and / or, the proximal end of the main body portion has the tapered portion.

3. The aneurysm occlusion device according to claim 1, characterized in that, The second end faces the interior of the sealing body.

4. The aneurysm occlusion device according to claim 1, characterized in that, It also includes a connecting ring corresponding to the closing portion, with the second end gathered at the corresponding connecting ring.

5. The aneurysm occlusion device according to claim 1, characterized in that, The plugging body and / or the support body are made of shape memory or elastic materials, and the distal and proximal ends of the support body are used to support the plugging body, respectively.

6. The aneurysm occlusion device according to claim 1, characterized in that, When the aneurysm occlusion device is in the deployed state, the outer diameter of the occlusion body gradually increases and then gradually decreases along the direction from distal to proximal; or When the aneurysm occlusion device is in the deployed state, the occlusion body has a cylindrical structure.

7. The aneurysm occlusion device according to claim 1, characterized in that, The maximum outer diameter of the sealing body is greater than or equal to the maximum outer diameter of the support body.

8. The aneurysm occlusion device according to claim 1, characterized in that, The distal end of the tubular body has a tapered structure; and / or, the proximal end of the tubular body has a tapered structure.

9. The aneurysm occlusion device according to claim 1, characterized in that, The spring coil includes a tubular body, which is formed by spirally winding spring wire along the length of the tubular body.

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