A kind of agricultural acaricide composition and its application

Abstract

The present invention provides an agricultural acaricidal composition containing two active components A and B, wherein the active component A is selected from chlorfenapyr, and the active component B is selected from bifenazate or fluazinam, and the weight ratio of the two active components A and B is 1-80:80-1. The present invention also provides a pesticide preparation containing the acaricidal composition. The acaricidal composition and pesticide preparation provided by the present invention are not only superior to a single agent in terms of quick-acting property and lasting effect, but also can reduce the dosage of pesticides used, and have a good control effect on agricultural pest mites that have developed serious resistance to etoxazole and pyridaben, which is beneficial to environmental protection and the comprehensive control of agricultural pest mites.

Description

Technical Field

[0001] The invention belongs to the field of pesticides, and in particular relates to a high-efficiency, low-toxic and environmentally friendly acaricide composition containing dual active components of chlorfenapyr and bifenazate or fluazinam and an application thereof. Background Art

[0002] In the process of agricultural production, the use of chemical agents to control plant diseases is one of the most effective means. However, the long-term and continuous use of a single chemical component at high doses causes serious resistance in pests and mites. In recent years, the control of herbivorous agricultural mites has become a difficult problem in agricultural production, and the resistance problem has become prominent. In order to more effectively control mites and delay their resistance to chemical agents, the compounding of compounds with different mechanisms of action is an economical and efficient means.

[0003] Chlorfenapyr is an acrylonitrile miticide independently developed by Zhejiang Chemical Research Institute Co., Ltd. Its chemical structure is shown in the following formula (I). A patent has been applied for (publication number: CN108570008A). Its mechanism of action is to transform into hydroxyl compounds through metabolism, thereby acting on the electron transport chain of the respiratory system, disrupting the action of succinate dehydrogenase, inhibiting the normal function of mitochondria, and achieving a preventive and therapeutic effect. It has high biological activity against adult mites, nymphs, and eggs:

[0004]

[0005] The common English name of bifenazate is bifenazate, which is a new type of hydrazine ester compound. It is non-systemic and has a contact killing effect. It mainly acts on the central nervous conduction system of mites, inhibiting the conduction of the central nervous system, thereby achieving the purpose of killing mites. It is effective for all life stages of mites.

[0006] The common English name of fluazinam is fluazinam, which belongs to the dinitroaniline fungicide and acaricide. It is a broad-spectrum and highly effective protective fungicide. It is very effective against Alternaria, Phytophthora, Monospinella, Sclerotinia and Venturia.

[0007] At present, bifenazate and fluazifop have problems such as large dosage, high cost of use, short duration of effectiveness, and gradually increasing resistance, which lead to certain limitations in their promotion and application, thus seriously shortening the product life cycle.

[0008] Currently, the time, financial cost and difficulty required for the research and development of new compounds are increasing. There is an urgent need to develop high-efficiency, low-toxicity, and low-residue compound and mixed preparations to enable the scientific and rational mixing of different types of acaricides, which is of great significance to agricultural pest control. Summary of the invention

[0009] In order to solve the above technical problems, the present invention provides an agricultural acaricide composition and its application which has synergistic effect, high efficiency, low toxicity, long lasting effect and can control the drug resistance of harmful mites.

[0010] The purpose of this invention is achieved through the following technical solutions:

[0011] An agricultural acaricidal composition contains two active ingredients A and B, wherein the component A is chlorfenapyr and the component B is selected from bifenazate or fluazinam.

[0012] In the acaricidal composition provided by the present invention, the weight percentage of the two active components A and B is 1-80:80-1; preferably, the weight percentage of the two active components A and B is 1-40:40-1; more preferably, the weight percentage of the two active components A and B is 1-30:20-1.

[0013] The active component A and active component B of the present invention can be compounded as effective ingredients to form a pesticide preparation, which contains 1 to 80% by weight of the above-mentioned acaricide composition, and the rest are acceptable carriers and adjuvants in the pesticide preparation.

[0014] The pesticide preparation can be formulated into the following dosage forms: emulsifiable concentrate, suspension concentrate, suspoemulsion, wettable powder, water dispersible granules or aqueous emulsion.

[0015] The total mass content of the two active components A and B in the pesticide preparation is 1% to 80%. The cumulative content range of the active components varies according to the type of preparation. Generally, the cumulative content of the active components in the liquid preparation is between 1% and 60%, preferably 10% to 40%. The cumulative content of the active components in the solid preparation is between 5% and 75%, preferably 10% to 60%.

[0016] The pesticide formulation of the present invention contains at least one surfactant to facilitate the dispersion of the active ingredient in water during application. The cumulative content of the surfactant is between 5% and 28%, and the balance is a solid or liquid carrier. The surfactant selected for the acaricide composition of the present invention is well known to those skilled in the art, such as: one or more of a dispersant, a wetting agent, a binder, a defoamer, a stabilizer or an emulsifier. Depending on the dosage form, the formulation may also contain an antifreeze agent, a thickener, a disintegrant, etc., which are well known to those skilled in the art.

[0017] The acaricide composition of the present invention can be diluted or used directly by the user before use. The preparation thereof can be prepared by methods known to those skilled in the art, that is, after mixing the active substance with a liquid solvent or a solid carrier, a surfactant is added.

[0018] The acaricide composition of the present invention comprises the following components when it is made into emulsifiable concentrate: active component A: 1-50%, active component B: 1-40%, emulsifier: 5-25%, synergist: 10-20%, cosolvent: 3-27%, and the solvent is supplemented to 100%. Active components A and B are added into the solvent and completely dissolved, and then the emulsifier, synergist, etc. are added, and stirred evenly to form a uniform and transparent oily liquid, so as to obtain the emulsifiable concentrate product of the composition of the present invention.

[0019] The acaricide composition of the present invention comprises the following components when it is made into a suspension: active component A: 1-40%, active component B: 10-50%, dispersant: 7-13%, wetting agent: 5-20%, defoamer: 0.4-1%, thickener: 0.1-2.5%, binder: 0.5-2%, antifreeze agent: 0.5-10%, and water is added to 100%. The weighed dispersant, wetting agent, antifreeze agent, preservative and defoamer are added into water, stirred to disperse evenly, then the measured active component is added and stirred to form a fluid, and finally the mixture is added into a sand mill and ground until D90 is less than or equal to 5 microns, and then filtered to obtain the suspension product of the composition of the present invention.

[0020] The acaricidal composition of the present invention comprises the following components when it is made into an aqueous emulsion: active component A: 0.1-40%, active component B: 10-50%, solvent: 5-20%, emulsifier: 5-30%, antifreeze: 2-5%, thickener: 0.2-2%, defoamer: 0.1-6%, and deionized water makes up the balance. Active components A and B, solvent, emulsifier, and cosolvent are added together and dissolved into a uniform oil phase; part of water, antifreeze, thickener, defoamer, etc. are mixed together to form a uniform water phase. While stirring at high speed in a reaction kettle, the oil phase is added to the water phase, and the remaining water is made up to the phase transition point. The aqueous emulsion product of the composition of the present invention is obtained by high-speed shearing for half an hour.

[0021] The acaricide composition of the present invention comprises the following components when it is made into a soluble liquid: active component A: 1-40%, active component B: 10-50%, emulsifier: 1-20%, synergist: 3-12%, and the organic solvent is added to 100%. The active components A and B, the organic solvent, the emulsifier, the synergist, etc. are mixed together to form a uniform transparent liquid, thus obtaining the soluble liquid product of the composition of the present invention.

[0022] The acaricide composition of the present invention comprises the following components when it is made into water-dispersible granules: active component A: 0.1-50%, active component B: 10-50%, dispersant: 3-10%, wetting agent: 1-10%, disintegrant: 1-5%, binder: 1-8%, and the balance is made up of solid carrier. The active components A and B, dispersant, wetting agent, disintegrant, binder, solid carrier, etc. are pulverized together by an ultra-fine air flow mill to obtain the required particle size, and then the binder and other auxiliary agents are added to obtain the granulation material. The material is quantitatively sent into a fluidized bed granulation dryer for granulation and drying and sieving, and the water-dispersible granule product of the composition of the present invention is obtained.

[0023] The solid carrier of the present invention is selected from but not limited to: minerals, plants, synthetic fillers and inorganic salts. Minerals include silicates, carbonates, sulfates and oxides. Silicates include kaolin, sepiolite, pearl clay, montmorillonite, mica, vermiculite, pyrophyllite and talc. Carbonates include calcium carbonate, calcite and dolomite. Sulfates include ammonium sulfate, sodium sulfate and calcium sulfate. Oxides include quicklime, magnesium lime and diatomaceous earth. Plants include citrus residue powder, corn cob residue powder, husk powder, rice husk powder, soybean straw powder, tobacco powder, walnut shell powder and sawdust powder. Synthetic fillers include precipitated calcium carbonate hydrate, precipitated calcium carbonate and white carbon black. Inorganic salts include potassium chloride and sodium chloride. In addition, there are pumice and natural sand.

[0024] The liquid carrier of the present invention includes, but is not limited to: aromatic hydrocarbons, such as benzene, xylene, trimethylbenzene, toluene; chlorinated aliphatic hydrocarbons, such as chloroform, dichloromethane, chloroform, carbon tetrachloride and polychlorinated ethane; aliphatic hydrocarbons, such as petroleum fractions, cyclohexane, light mineral oil and paraffin; alcohols, such as methanol, ethanol, isopropanol, butanol, ethylene glycol, propylene glycol, glycerol, fatty alcohols, etc.; ethers, such as propylene glycol ethyl ether, petroleum ether, etc.; ketones, such as acetone, cyclohexanone, N-methyl-pyrrolidone, N-octylpyrrolidone, etc.; special solvents such as dimethylformamide, dimethyl sulfoxide, polyethylene glycol, etc.; vegetable oil and methylated vegetable oil. The above organic solvents can be used alone, mixed, or mixed with water.

[0025] The emulsifiers of the present invention include, but are not limited to, nonionic emulsifiers, anionic emulsifiers and cationic emulsifiers. Nonionic emulsifiers are selected from polyoxyethylene ethers, polyoxypropylene ethers, ethylene oxide / propylene oxide block copolymers, polyol fatty acid esters, polyvinyl alcohol, etc.; anionic emulsifiers are selected from fatty acid soaps, alkyl sulfates (sodium dodecyl sulfate), alkyl benzene sulfonates (sodium dodecyl benzene sulfonate), phosphates, etc.; cationic emulsifiers are selected from N-dodecyl dimethylamine, quaternary ammonium salts, etc.

[0026] The dispersant of the present invention includes but is not limited to: at least one of sodium lignin sulfonate, calcium lignin sulfonate, sodium tripolyphosphate, sodium hexametaphosphate, sodium pyrophosphate, sodium salt of acrylic acid homopolymer, disodium maleate, sodium salt of naphthalenesulfonic acid formaldehyde condensate, triphenyl phenol polyoxyethylene ether phosphate, triethylhexyl phosphoric acid, sodium dodecyl sulfate, cellulose derivatives, polyacrylamide, guar gum, fatty acid polyethylene glycol esters, and sodium salt of p-hydroxyphenyl lignin sulfonate.

[0027] The wetting agent of the present invention includes but is not limited to: at least one of tea dregs, sodium dodecylbenzene sulfonate, washing powder, silkworm feces, sodium lauryl sulfonate, fatty alcohol polyoxyethylene ether, naphthalene sulfonate, sodium dodecyl sulfate, pull-opening powder, and alkylphenol resin polyoxyethylene ether sulfate.

[0028] The binder of the present invention is selected from at least one of organic bentonite, xanthan gum, magnesium aluminum silicate, sodium alginate, sodium carboxymethyl cellulose, organic polymer, fumed silica, gum arabic and polyvinyl alcohol.

[0029] The synergist of the present invention is selected from one of an organosilicon pesticide synergist, an organosilicon pesticide penetrant extender, an agricultural organosilicon pesticide synergist, azone, and heptamethyltrisiloxane.

[0030] The pesticide preparation containing the acaricidal composition of the present invention is particularly suitable for controlling agricultural pest mites, including citrus mites, cinnabarinus spider mites, apple red spider mites, cotton red spider mites, two-spotted spider mites, hawthorn spider mites, tea yellow mites, ovate short-palped mites or tyrophagus rot in fruit trees, vegetables, cotton, soybeans, tea trees or flowers.

[0031] The acaricidal composition of the present invention has the following advantages over the prior art:

[0032] (1) The acaricide composition of the present invention exhibits a good synergistic effect by compounding two active components within a certain ratio range, which is significantly improved compared with its single agent, and has the advantages of good rapid effect and long lasting effect;

[0033] (2) Reduce the dosage and cost of use;

[0034] (3) Rationally mixing two pesticides with different modes of action and different mechanisms of action on mites can not only extend the service life of the pesticides, but also delay the development of pesticide resistance in mites;

[0035] (4) It can effectively control two-spotted spider mites and other resistant mites that have developed serious resistance to acaricides such as etoxazole and pyraclostrobin;

[0036] (5) The composition is low in toxicity and high in efficacy, safe to beneficial insects and natural enemies, and has good environmental compatibility. It can be widely used in agricultural fields where registration of other drugs such as etoxazole has been stopped due to safety risks to aquatic organisms. DETAILED DESCRIPTION

[0037] The present invention is further described below in conjunction with specific embodiments, but the present invention is not limited to these specific embodiments. Those skilled in the art should recognize that the present invention covers all possible alternatives, improvements and equivalents within the scope of the claims.

[0038] The material formulations in the following examples can be selected according to local conditions and have no substantial effect on the results. In these examples, unless otherwise specified, all percentages are weight percentages.

[0039] The inventors conducted an indoor toxicity test on the mixture of active component A and active component B.

[0040] The test was conducted with reference to the Indoor Bioassay Test Guidelines for Pesticides (Agricultural Industry Standard NY / T1154.7-2006) and the SOP for the Evaluation of Pesticide Biological Activity (Pesticide Volume), using the immersion method.

[0041] The combined effect is calculated using the following method:

[0042]

[0043] Theoretical toxicity index (TTI) = toxicity index of A × content of A in the mixture (%)

[0044] + Toxicity index of B × content of B in the mixture (%)

[0045]

[0046] If the co-toxicity coefficient is greater than 120, it indicates a synergistic effect; if it is less than 80, it indicates an antagonistic effect; if it is greater than 80 and less than 120, it indicates an additive effect.

[0047] Example 1: Example of mixing chlorfenapyr and bifenazate

[0048] Table 1. Synergistic effect of chlorfenapyr and bifenazate on strawberry two-spotted spider mite Tetranychus urticae Koch

[0049]

[0050]

[0051] From the results of indoor biological activity determination in Table 1, it can be seen that the co-toxicity coefficient of chlorfenapyr and bifenazate in the mass ratio range of 1-10 to 10-1 is greater than 120, and both show synergistic effects on strawberry two-spotted spider mites, and the co-toxicity coefficient is optimal when the mass ratio ranges from 1-10 to 5-1. At present, the damage range of two-spotted spider mites is increasing day by day, and they have developed very serious resistance, and have encountered great difficulties in chemical control. The mixing of chlorfenapyr and bifenazate is reasonable, feasible and has broad market prospects.

[0052] Example 2: Example of mixing chlorfenapyr and fluazinam

[0053] Table 2. Synergistic effect of chlorfenapyr and fluazinam on Panonchus citri Mc Gregor

[0054]

[0055] From the results of indoor biological activity determination in Table 2, it can be seen that the co-toxicity coefficients of chlorfenapyr and fluazinam in the mass ratio range of 1-30 to 20-1 are all greater than 120, showing a synergistic effect on citrus mites, and the co-toxicity coefficient is optimal when the mass ratio is in the range of 1-3 to 5-1. The mixture of chlorfenapyr and fluazinam can not only comprehensively control the harm of mites, but also prevent fungal diseases such as blight, black spot, gray mold, and sclerotinia of vegetables. It has multiple effects with one drug, significantly reduces the dosage, can effectively delay the drug resistance of harmful mites and pathogens, is safe for crops and the environment, and has broad market development prospects.

[0056] Example 3 25% chlorfenapyr-bifenazate emulsion in water

[0057] Chlorfenapyr 5%, bifenazate 20%, ethylene glycol methyl ether 3%, N-pyrrolidone 5%, agricultural milk 600 # 10%, silicone compound 0.3%, organosilicon defoamer 0.4%, propylene glycol 3%, deionized water supplemented to 100%, the above raw materials are prepared according to the conventional processing technology of water emulsion, and after mixing, 25% chlorfenapyr-bifenazate water emulsion can be prepared.

[0058] Test method: Field efficacy test of 25% chlorfenapyr·bifenazate emulsion in water for controlling strawberry two-spotted spider mites. This test was conducted at the strawberry planting base in Dongpu Town, Shaoxing City, Zhejiang Province, and the strawberry variety tested was Hongyan. The row spacing of strawberry plants was about 30cm×50cm, and the area of ​​each plot was 10㎡. It was repeated 3 times and arranged in random blocks. The spraying equipment was a Shuangshou brand 3WBD-16B backpack electric sprayer produced by Shuangshou Plastic Products Factory, Jiaojiang, Taizhou City, Zhejiang Province, with a working pressure of 0.15-0.4MPa. The test concentrations of 25% chlorfenapyr·bifenazate emulsion in water were 62.5 and 83mg / L, and the test concentrations of the control agent 20% chlorfenapyr suspension were 100mg / L, 30% cypermethrin suspension was 150mg / L, and 43% bifenazate suspension was 215mg / L. A blank control treatment was also set up. Spray the stems and leaves, using 40 liters of water per mu, and apply the medicine once.

[0059] Survey method: Mark 30 leaves at equal intervals on each plant in each plot, observe and count the base number of mites before application and the number of live mites on the front and back of the marked leaves 1, 3, 7, and 14 days after application, and calculate the control effect. At the same time, observe the growth of strawberries, and visually test whether the pesticide causes chlorosis, yellowing, deformity, necrosis, and other symptoms of strawberry damage.

[0060] Calculation method of drug efficacy:

[0061]

[0062] Table 3. Field test results of 25% chlorfenapyr-bifenazate emulsion in water against strawberry two-spotted spider mite

[0063]

[0064] The test data in Table 3 show that: the control effect of 25% chlorfenapyr·bifenazate emulsion on strawberry two-spotted spider mites at the dosage of 62.5 mg / L and 83 mg / L of active ingredient was significantly better than that of the control agent at the test dosage 1 day, 3 days, 7 days and 14 days after the application. The control effect of 25% chlorfenapyr·bifenazate emulsion on strawberry two-spotted spider mites was significant at 1 day, 3 days, 7 days and 14 days after the application, all exceeding 90%, and it can quickly reduce the insect population base. In the investigation at various stages after the application, the control agent 30% cypermethrin·bifenazate suspension was slightly better than the control effect of 20% chlorfenapyr suspension at the dosage of 100 mg / L of active ingredient; 14 days after the application, the control effects of the two treatments were close and there was no significant difference. The control agent 30% cypermethrin suspension reached the best control effect of 80.64% at the dosage of 150mg / L of active ingredient 7 days after application; the control agent 43% bifenazate suspension reached 86.14% control effect on strawberry two-spotted spider mites 3 days after application, indicating that bifenazate has better rapid effect than cypermethrin; while the control effect of 43% bifenazate suspension was only 76.73% 14 days after application, and the persistence was not enough. After chlorfenapyr and bifenazate were combined, the synergistic effect was significant, and the control effect reached 98.37% 3 days after application, which can quickly reduce the insect population base and effectively control the harm of harmful mites. The rapid effect and persistence period are significantly better than the control agent, and it can replace the acaricide that is resistant to strawberry two-spotted spider mites, thereby reducing the number of strawberry medications during the fruiting period and reducing the risk of pesticide residues on the fruit surface. In addition, during the test, it was found that the pesticide composition of the present invention had no phytotoxic effects on the growth of strawberries and fruits, and no adverse effects of the test agent on bees and beneficial natural enemies were observed.

[0065] Example 4: Example of mixing chlorfenapyr and bifenazate

[0066] Table 4. Field efficacy test results of 20% chlorfenapyr-bifenazate suspoemulsion against citrus mites

[0067]

[0068] The test data in Table 4 show that the control effect of 20% chlorfenapyr·bifenazate suspension emulsion on citrus panonychus mites at the dosage of 40 mg / L of active ingredient was better than that of the control agents 20% chlorfenapyr suspension, 30% cypermethrin suspension and 43% bifenazate suspension at the test dosage at 1 day, 3 days, 7 days, 14 days, 21 days and 30 days after application. The control effect of 20% chlorfenapyr·bifenazate suspension emulsion at the dosage of 40 mg / L of active ingredient at 1-7 days after application was slightly lower than that of 30% cypermethrin·bifenazate suspension at the dosage of 75 mg / L of active ingredient, but 20% chlorfenapyr·bifenazate suspension emulsion showed better persistence 14 days after application, and the control effect still reached 86.29% at 30 days after application. The 20% chlorfenapyr·bifenazate suspension emulsion, at an active ingredient dosage of 67 mg / L, had a control effect of 98.23% and 99.45% on citrus mites 3 days and 7 days after application, respectively, which can quickly control the damage of mites. The control agent 30% cypermethrin suspension, at an active ingredient dosage of 150 mg / L, had a control effect of 71.05% on citrus mites 3 days after application, and the control effect decreased to 50.26% 30 days after application. The control agent 43% bifenazate suspension had a control effect of 83.18% on citrus mites 7 days after application, and the control effect decreased to 55.38% 30 days after application. After chlorfenapyr and bifenazate were combined, the synergistic effect was significant, especially within 30 days after application, it could effectively control the damage of mites, and the rapidity and duration of effect were significantly better than the control agent. In addition, during the test, it was found that the pesticide composition of the present invention had no phytotoxic effect on the growth of citrus, and no adverse effects of the test agent on beneficial natural enemies were observed.

[0069] Example 5 30% chlorfenapyr·fluazinam water dispersible granules

[0070] 10% of chlorfenapyr, 30% of fluazinam, 5% of sodium lauryl sulfate, 6% of calcium benzenesulfonate, 10% of alkylphenol polyoxyethylene ether, 8% of white carbon black, and kaolin to make up to 100%. The above raw materials are mixed evenly according to the conventional preparation method to prepare 40% chlorfenapyr·fluazinam water-dispersible granules.

[0071] Test method: Field efficacy test of 40% chlorfenapyr·fluazinam water dispersible granules for controlling two-spotted spider mites in roses. The test site was conducted at the flower planting base in Keqiao District, Shaoxing City, Zhejiang Province, and the test rose variety was white rose (etoxazole and spiroclofen are often used to control two-spotted spider mites). Greenhouse planting, 5 pots of roses per plot, repeated 3 times, and arranged in random blocks. The spraying equipment was a Shuangshou brand 3WBD-16B backpack electric sprayer produced by Shuangshou Plastic Products Factory, Jiaojiang, Taizhou City, Zhejiang Province, with a working pressure of 0.15~0.4MPa.

[0072] Test dosage: 40% chlorfenapyr·fluazinam water dispersible granules test concentration is 66.7, 80mg / L, control agent 30% cypermethrin·fluazinam suspension 100mg / L, control agent 20% chlorfenapyr suspension 100mg / L, 50% fluazinam suspension 250mg / L, 20% etoxazole suspension 180mg / L (6 times the registered dosage), 240g / L spiroclofonate suspension 360mg / L (6 times the registered dosage), and a blank control treatment is set up. Spray the whole plant, the water consumption for each pot of rose is about 0.4L, spray the front and back of the leaves evenly, and use the medicine once.

[0073] Survey method: Mark 4 leaves in 4 directions for each rose pot, take photos with a mobile phone magnifying glass, and investigate the number of live mites on 20 leaves per treatment as the pre-drug base number. Investigate the number of live mites in each plot 1d, 3d, 7d, 14d, 21d, and 30d after the drug, and calculate the control effect. At the same time, observe the growth and flowering of the rose, and visually observe whether the rose has chlorosis, yellowing, deformity and other drug damage symptoms. The efficacy calculation method is the same as Example 3.

[0074] Table 5. Field test results of 30% chlorfenapyr·fluazinam water dispersible granules against Chinese rose two-spotted spider mite

[0075]

[0076]

[0077] The test data in Table 5 show that the control effect of 40% chlorfenapyr·bifenazate water dispersible granules on rose two-spotted spider mites exceeded 97% at the dosage of 66.7mg / L and 80mg / L of the active ingredient, 1-7 days after application, which is significantly better than the control effect of other control agents at the test dosage. 21 days after application, the control effect of 40% chlorfenapyr·fluazinam water dispersible granules on rose two-spotted spider mites at each test dosage still exceeded 91%, while the control effect of 20% chlorfenapyr suspension reached 80.96%, and the control effect of 30% cypermethrin·fluazinam suspension reached only 74.51%. The use amount of 20% etoxazole suspension and 240g / L spiroclofen suspension reached 6 times the registered dosage, and the control effect was not ideal, indicating that the two-spotted spider mites have developed serious resistance to these two types of agents, and the surviving two-spotted spider mites can still cause harm to the growth of roses. The data in Table 5 show that after the compounding of chlorfenapyr and fluazinam, the synergistic effect is significant, the insect population base can be quickly reduced one day after the drug is applied, and the harm of harmful mites can be effectively controlled. The dosage is small, the rapid effect and the lasting effect are significantly better than other control agents, and the harm of two-spotted spider mites that are resistant to agents such as etoxazole and spiroclofen can be effectively controlled. At the same time, the leaf spot disease that is common and easy to occur in roses can also be prevented. It is an ideal agent for the prevention and control of two-spotted spider mites and comprehensive prevention of diseases in roses. In addition, during the test, it was found that the pesticide composition of the present invention had no phytotoxic effect on the growth of roses, and no adverse effects of the test agent on beneficial natural enemies were observed.

[0078] In summary, the compound acaricide composition of chlorfenapyr and bifenazate or fluazinam of the present invention shows good control effect on citrus mites, strawberry two-spotted spider mites, rose two-spotted spider mites, etc., and is safe for target crops, beneficial natural enemies, users, and the environment. Compared with single-dose acaricides, the acaricide composition of the present invention has multiple action sites and is not easy to produce resistance with other acaricides; it can effectively solve the problem of controlling harmful mites in flower planting areas that have serious resistance to agents such as etoxazole and spiroclofen; one drug has multiple effects, which can reduce the amount of pesticides used, in line with the national policy guidelines for reducing drugs and increasing efficiency; good rapidity and long duration can significantly improve the efficiency of drug use, reduce drug costs and labor costs; it has a wide range of applications and is suitable for most crops harmed by mites. Therefore, the research and development and promotion of the present invention have important social significance, and will also generate huge economic value. It has great practical significance for increasing production and income of farmers in major fruit producing areas such as citrus and apples, major vegetable producing areas such as Solanaceae and melons, and major cash crop producing areas such as cotton and tea. It is worthy of wide promotion and application in agricultural production.

Claims

1. An agricultural acaricidal composition, characterized in that: The acaricidal composition contains two active components, the active component A is selected from chlorfenapyr, and the active component B is selected from bifenazate or fluazinam, and the weight percentage of the two active components A and B is 1-30:20-1.

2. The agricultural acaricidal composition according to claim 1, characterized in that: The weight ratio of the two active components A and B is 1-5:10-1.

3. A pesticide preparation, characterized in that: The pesticide preparation contains 1 to 80% by weight of the acaricidal composition according to any one of claims 1 to 2, and the rest are acceptable carriers and adjuvants in the pesticide preparation.

4. The pesticide formulation according to claim 3, characterized in that: The pesticide preparation can be formulated into emulsifiable concentrate, suspension concentrate, suspoemulsion, wettable powder, water dispersible granules or aqueous emulsion.

5. Use of the pesticide preparation according to any one of claims 3-4, characterized in that: The pesticide preparation is used for preventing and controlling agricultural harmful mites.

6. The use of the pesticide preparation according to claim 5, characterized in that: The agricultural pest mites include citrus mites, apple red spider mites, cotton red spider mites, two-spotted spider mites, tea yellow mites, ovate short-palped mites or tyrophagous mites in fruit trees, vegetables, cotton, soybeans, tea trees or flowers.

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