A nanofiber membrane based on multi-component cyclodextrin complex and cellulose acetate, and its preparation method and application

Abstract

The present invention provides a nanofiber membrane based on a multi-component cyclodextrin complex and cellulose acetate, which is prepared by electrospinning a spinning solution, wherein the spinning solution includes cellulose acetate, a cyclodextrin complex and dimethylformamide; the cyclodextrin complex includes sulfobutyl-β-cyclodextrin, β-cyclodextrin and hydroxypropyl-β-cyclodextrin. The multi-component cyclodextrin complex / cellulose acetate (CA / CD) solution used in the present invention introduces anionic cyclodextrin-sulfobutyl-β-cyclodextrin into the multi-component cyclodextrin complex, which not only increases the hydrogen bonding effect of the membrane material but also increases the electrostatic interaction, and has obvious adsorption for nicotine and PM particles. The present invention also provides a preparation method and application of a nanofiber membrane based on a multi-component cyclodextrin complex and cellulose acetate.

Description

Technical Field

[0001] The present invention belongs to the technical field of nano-membrane materials, and in particular relates to a nanofiber membrane based on a multi-component cyclodextrin complex and cellulose acetate, and a preparation method and application thereof. Background Art

[0002] Cigarette smoke contains over 70 carcinogens, the main toxic and harmful substances including nicotine, polycyclic aromatic hydrocarbons, formaldehyde, argon, carbon monoxide, nitrogen oxides, benzene, hydrogen cyanide, ammonia, phenol, acetaldehyde, argon, acetone, and pyridine. These toxic and harmful substances are not only highly addictive but also major pollutants in environmental tobacco smoke. Therefore, reducing the nicotine content and carcinogenic compounds in cigarette smoke is of great significance.

[0003] Commercial cigarette filters are made of cellulose acetate (CA), a modified natural polymer. Cellulose acetate is a chemically modified polymer obtained by acetylation of the hydroxyl groups in the cellulose molecule with acetic acid. It exhibits excellent flexibility, breathability, hydrophilicity, plasticity, and biocompatibility, and is also cost-effective. However, current commercial cigarette filters suffer from low adsorption efficiency for harmful substances in cigarette smoke. Summary of the Invention

[0004] The present invention provides a nanofiber membrane based on a multi-component cyclodextrin complex and cellulose acetate, a preparation method and application thereof. The nanofiber membrane of the present invention can improve the adsorption effect of nicotine and PM particles in cigarette smoke.

[0005] The present invention provides a nanofiber membrane based on a multi-component cyclodextrin complex and cellulose acetate, which is prepared by electrospinning a spinning solution.

[0006] The spinning solution comprises cellulose acetate, cyclodextrin complex and dimethylformamide;

[0007] The cyclodextrin complex includes sulfobutyl-β-cyclodextrin, β-cyclodextrin and hydroxypropyl-β-cyclodextrin.

[0008] Preferably, the mass ratio of the cellulose acetate and cyclodextrin complex is (0.5-1):(0.15-0.3).

[0009] Preferably, in the cyclodextrin complex, the mass ratio of sulfobutyl-β-cyclodextrin, β-cyclodextrin and hydroxypropyl-β-cyclodextrin is (0.05-0.1):(0.05-0.1):(0.05-0.1).

[0010] Preferably, the fiber diameter of the nanofiber membrane based on the multi-component cyclodextrin complex and cellulose acetate is 100-200 nm.

[0011] The present invention provides a method for preparing a nanofiber membrane based on a multi-component cyclodextrin complex and cellulose acetate as described above, comprising the following steps:

[0012] A) dissolving the cellulose acetate and cyclodextrin complex in dimethylformamide, stirring and then ultrasonicating to obtain a spinning solution;

[0013] B) electrospinning the spinning solution to obtain a nanofiber membrane.

[0014] Preferably, the stirring time in step A) is 3 to 6 hours; the ultrasonication time in step A) is 1 to 2 hours.

[0015] Preferably, the voltage of the electrospinning is 25-30 kV, the propulsion speed of the propeller is 0.1-0.5 mm / min, the electrospinning distance is 10-30 cm, and the rotation speed of the receiver is 200-600 rpm.

[0016] Preferably, the electrospinning further includes drying, the drying temperature is 40 to 80° C., and the drying time is 8 to 12 hours.

[0017] The present invention provides use of the nanofiber membrane based on the multi-component cyclodextrin complex and cellulose acetate as described above in preparing a cigarette filter material.

[0018] Preferably, the nanofiber membrane composed of the multi-component cyclodextrin complex and cellulose acetate is used to adsorb nicotine and PM particles in cigarette smoke.

[0019] The present invention provides a nanofiber membrane based on a multi-component cyclodextrin complex and cellulose acetate, which is prepared by electrospinning a spinning solution, wherein the spinning solution includes cellulose acetate, a cyclodextrin complex and dimethylformamide; the cyclodextrin complex includes sulfobutyl-β-cyclodextrin, β-cyclodextrin and hydroxypropyl-β-cyclodextrin.

[0020] Compared with the existing technology, this application has the following advantages:

[0021] (1) The multi-component cyclodextrin complex / cellulose acetate (CA / CD) solution used in the present invention can be mixed in one step without complicated synthesis steps, with high raw material utilization and no pollution to the environment.

[0022] (2) The multi-component cyclodextrin complex / cellulose acetate (CA / CD) solution used in the present invention introduces anionic cyclodextrin, sulfobutyl-β-cyclodextrin, into the multi-component cyclodextrin complex, which not only increases the hydrogen bonding effect of the membrane material but also increases the electrostatic interaction.

[0023] (3) The multi-component cyclodextrin complex / cellulose acetate (CA / CD) membrane used in the present invention exhibits significant adsorption for nicotine and PM particles. Compared to commercial cigarette filters, the membrane obtained in the present invention has a seven-fold increase in nicotine adsorption efficiency and can filter PM particles larger than 0.5 μm. BRIEF DESCRIPTION OF THE DRAWINGS

[0024] In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the following briefly introduces the drawings required for use in the embodiments or the description of the prior art. Obviously, the drawings described below are merely embodiments of the present invention. For ordinary technicians in this field, other drawings can be obtained based on the provided drawings without paying any creative work.

[0025] Figure 1 Scanning electron micrographs of nanofiber membranes. (a) (b) are CA nanofiber membranes, (c) (d) are CA / β-CD membranes, (e) (f) are CA / SBE-β-CD membranes, (g) (h) are CA / HP-β-CD membranes, and (i) (j) are CA / CD membranes.

[0026] Figure 2 Macroscopic images of the CA / CD film prepared in Example 5 (a) folded and (b) unfolded;

[0027] Figure 3 The infrared spectra (FT-IR) of the CA film prepared in Example 1 and the CA / CD film prepared in Example 5 are shown;

[0028] Figure 4 Thermogravimetric images (FT-IR) of the CA film prepared in Example 1 and the CA / CD film prepared in Example 5;

[0029] Figure 5 (a) is the UV spectrum of the methanol absorption liquid of filtered cigarette smoke, and (b) is the comparison of the nicotine filtration efficiency of commercial filter membranes and CA / CD membranes;

[0030] Figure 6 is the infrared spectrum of the filter membrane after filtration;

[0031] Figure 7 Scanning electron micrographs of the filter membranes after filtration: (a, b, c) CA membranes; (d, e, f) CA / CD membranes;

[0032] Figure 8 Transmission electron micrographs of the CA / CD membrane (a) before and (b) after filtering cigarette smoke.

[0033] Figure 9 This is the nicotine filtration experimental device of the present invention. DETAILED DESCRIPTION

[0034] The present invention provides a nanofiber membrane based on a multi-component cyclodextrin complex and cellulose acetate, which is prepared by electrospinning a spinning solution.

[0035] The spinning solution comprises cellulose acetate, cyclodextrin complex and dimethylformamide;

[0036] The cyclodextrin complex includes sulfobutyl-β-cyclodextrin, β-cyclodextrin and hydroxypropyl-β-cyclodextrin.

[0037] In the present invention, the acetylation degree of the cellulose acetate is preferably 35-40 wt%, more preferably 39.8 wt%, the hydroxyl content is preferably 3-4 wt%, more preferably 3.5 wt%, and the Mw is preferably 20,000-50,000, more preferably 30,000.

[0038] In the present invention, the cyclodextrin complex preferably includes sulfobutyl-β-cyclodextrin, β-cyclodextrin and hydroxypropyl-β-cyclodextrin. The present invention introduces anionic cyclodextrin, sulfobutyl-β-cyclodextrin, into the multi-component cyclodextrin complex, which not only increases the hydrogen bonding effect of the membrane material but also increases the electrostatic interaction. The hydrogen bonding effect and electrostatic interaction enrich the adsorption force, increase the adsorption sites, and improve the membrane's adsorption effect on pollutants with hydrogen bonds and positive charges.

[0039] In the present invention, in the cyclodextrin complex, the mass ratio of sulfobutyl-β-cyclodextrin, β-cyclodextrin and hydroxypropyl-β-cyclodextrin is preferably (0.05-0.1):(0.05-0.1):(0.05-0.1), more preferably (0.05-0.0.08):(0.05-0.08):(0.05-0.08), and most preferably 0.05:0.05:0.05.

[0040] In the present invention, the mass ratio of the cellulose acetate and cyclodextrin complex is preferably (0.5-1):(0.15-0.3), more preferably (0.5-0.8):(0.15-0.2), and most preferably 0.5:0.15.

[0041] In the present invention, dimethylformamide is a solvent. In the prior art, acetone, dimethylacetamide, and the like are commonly used solvents for spinning cellulose acetate. However, the multi-component cyclodextrin complex used in this application has a low solubility in acetone, resulting in poor spinning effect. The use of dimethylformamide as a solvent increases the solubility of the multi-component cyclodextrin complex.

[0042] In the present invention, the mass ratio of dimethylformamide to cellulose acetate is preferably 1:(0.5-1), more preferably 1:(0.6-0.8), such as 1:0.5, 1:0.6, 1:0.7, 1:0.8, 1:0.9, 1:1, and preferably a range value with any of the above values ​​as the upper or lower limit.

[0043] The nanofiber membrane of the present invention has closely arranged fibers, uniform size and distribution, and significantly reduced droplet-like structures and spider-web-like structures. The fiber diameter of the nanofiber membrane is preferably 100-200 nm.

[0044] The present invention also provides a method for preparing a nanofiber membrane based on a multi-component cyclodextrin complex and cellulose acetate, comprising the following steps:

[0045] A) dissolving the cellulose acetate and cyclodextrin complex in dimethylformamide, stirring and then ultrasonicating to obtain a spinning solution;

[0046] B) electrospinning the spinning solution to obtain a nanofiber membrane.

[0047] In the present invention, the types and amounts of the cellulose acetate, cyclodextrin complex and dimethylformamide are consistent with those described above, and the present invention will not repeat them here.

[0048] The invention dissolves cellulose acetate and cyclodextrin complex in dimethylformamide, stirs and then performs ultrasonic treatment to obtain a uniform and transparent spinning solution.

[0049] In the present invention, the stirring time is preferably 3 to 6 hours, more preferably 3 to 5 hours, and the ultrasonic time is preferably 1 to 2 hours.

[0050] After obtaining the spinning solution, the present invention transfers the spinning solution into a syringe for electrostatic spinning.

[0051] In the present invention, the voltage of the electrospinning is preferably 25 to 30 kV, more preferably 26 to 29 kV, the propulsion speed of the propeller is preferably 0.1 to 0.5 mm / min, more preferably 0.2 to 0.4 mm / min, and most preferably 0.2 to 0.3 mm / min; the electrospinning distance (the distance between the needle and the receiver) is preferably 10 to 30 cm, more preferably 15 to 25 cm, and most preferably 15 to 20 cm; the rotation speed of the receiver is preferably 200 to 600 rpm, more preferably 300 to 500 rpm, and most preferably 350 to 400 rpm.

[0052] After the electrospinning is completed, the present invention collects the obtained wet film from the receiver and dries it to obtain a nanofiber membrane.

[0053] In the present invention, the drying temperature is preferably 40 to 80° C., more preferably 50 to 70° C., and most preferably 60 to 65° C., and the drying time is preferably 8 to 12 hours, more preferably 9 to 10 hours.

[0054] The present invention also provides an application of the nanofiber membrane based on the multi-component cyclodextrin complex and cellulose acetate described above in the preparation of cigarette filter materials. The nanofiber membrane in the present invention is mainly used to improve the adsorption capacity of nicotine and PM particles in cigarette smoke. Experimental results show that the filtration efficiency of the nanofiber membrane based on the multi-component cyclodextrin complex and cellulose acetate in the present invention for nicotine is 8 times that of commercial adsorption materials. At the same time, it can filter out large-sized PM particles, and the diameter of the remaining PM particles is within 0.5 μm.

[0055] The present invention provides a nanofiber membrane based on a multi-component cyclodextrin complex and cellulose acetate, which is prepared by electrospinning a spinning solution, wherein the spinning solution includes cellulose acetate, a cyclodextrin complex and dimethylformamide; the cyclodextrin complex includes sulfobutyl-β-cyclodextrin, β-cyclodextrin and hydroxypropyl-β-cyclodextrin.

[0056] Compared with the existing technology, this application has the following advantages:

[0057] (1) The multi-component cyclodextrin complex / cellulose acetate (CA / CD) solution used in the present invention can be mixed in one step without complicated synthesis steps, with high raw material utilization and no pollution to the environment.

[0058] (2) The multi-component cyclodextrin complex / cellulose acetate (CA / CD) solution used in the present invention introduces anionic cyclodextrin, sulfobutyl-β-cyclodextrin, into the multi-component cyclodextrin complex, which not only increases the hydrogen bonding effect of the membrane material but also increases the electrostatic interaction.

[0059] (3) The multi-component cyclodextrin complex / cellulose acetate (CA / CD) membrane used in the present invention exhibits significant adsorption for nicotine and PM particles. Compared to commercial cigarette filters, the membrane obtained in the present invention has a seven-fold increase in nicotine adsorption efficiency and can filter PM particles larger than 0.5 μm.

[0060] In order to further illustrate the present invention, the following detailed description of a nanofiber membrane based on a multi-component cyclodextrin complex and cellulose acetate, its preparation method and application provided by the present invention is provided in conjunction with the examples, but it should not be understood as limiting the scope of protection of the present invention.

[0061] Example 1

[0062] Preparation of cellulose acetate (CA) electrospinning membrane

[0063] 0.5 g of cellulose acetate was dissolved in 5 mL of dimethylformamide and stirred for 2 hours until a homogeneous solution was formed. The solution was then transferred to a 5 mL syringe using a 23G needle and a high voltage of 25 kV applied at a propeller speed of 0.3 mm / min. The distance between the aluminum foil-covered receiver and the syringe tip was 20 cm, and the receiver rotation speed was 400 rpm. The resulting CA nanofiber membrane was collected directly from the aluminum foil-covered receiver, dried in an oven at 50°C overnight, and stored at room temperature.

[0064] Example 2

[0065] Preparation method of CA / β-CD electrospinning membrane

[0066] 0.5 g of cellulose acetate and 0.15 g of β-cyclodextrin were dissolved in 5 mL of dimethylformamide and stirred for 4 hours. The mixture was then transferred to a 5 mL syringe using a 23G needle and a high voltage of 25 kV at a propeller speed of 0.3 mm / min. The distance between the aluminum foil-covered receiver and the syringe tip was 20 cm, and the receiver rotation speed was 400 rpm. The resulting CA / β-CD nanofiber membrane was collected directly from the aluminum foil-covered receiver, dried in a 50°C oven overnight, and stored at room temperature.

[0067] Example 3

[0068] Preparation method of CA / SBE-β-CD electrospinning membrane

[0069] 0.5-1g of cellulose acetate and 0.1-0.2g of sulfobutyl-β-cyclodextrin (SBE-β-CD) were dissolved in 5mL of dimethylformamide. The solution was transferred to a 5mL syringe using a 20-24G needle, a high voltage of 25-30kV was applied, and the propeller speed was 0.3mm / min. The distance between the syringe tip and the aluminum foil-covered receiver was 10-30cm, and the receiver rotation speed was 200-600rpm. The resulting CA / SBE-β-CD nanofiber membrane was collected directly from the aluminum foil-covered receiver, dried in a 50°C oven overnight, and stored at room temperature.

[0070] Example 4

[0071] Preparation method of CA / HP-β-CD electrospinning membrane

[0072] 0.5 g of cellulose acetate and 0.15 g of hydroxypropyl-β-cyclodextrin (HP-β-CD) were dissolved in 5 mL of dimethylformamide and stirred for 3 hours. The solution was then transferred to a 5 mL syringe with a 20-24 Gauge needle. A high voltage of 25-30 kV was applied, and the propeller speed was 0.3 mm / min. The distance between the aluminum foil-covered receiver and the syringe tip was 20 cm, and the receiver rotation speed was 400 rpm. The resulting CA / HP-β-CD nanofiber membrane was collected directly from the aluminum foil-covered receiver, dried in a 50°C oven overnight, and stored at room temperature.

[0073] Example 5

[0074] Preparation method of CA / CD electrospinning membrane

[0075] 0.5 g of cellulose acetate, 0.05 g of β-cyclodextrin, 0.05 g of sulfobutyl-β-cyclodextrin, and 0.05 g of hydroxypropyl-β-cyclodextrin were dissolved in 5 mL of dimethylformamide. The solution was transferred to a 5 mL syringe using a 23G needle, a high voltage of 25 kV, and a propeller speed of 0.3 mm / min. The distance between the aluminum foil-covered receiver and the syringe tip was 20 cm, and the receiver rotation speed was 400 rpm. The resulting CA / CD nanofiber membrane was directly collected from the aluminum foil-covered receiver, dried in a 50°C oven overnight, and stored at room temperature.

[0076] Figure 3 The infrared spectra of the CA membrane prepared in Example 1 and the CA / CD electrospun membrane prepared in Example 5 are shown in FIG. Figure 3 It can be seen that the infrared spectrum of CA / CD film appears in the range of 3500-3200 cm -1 The strong broadband signal at 1150cm is the hydroxyl stretching vibration absorption of cyclodextrin. -1 The stretching vibration absorption of -C-OH is at 1030cm -1 The absorption at the 400 nm position is significantly enhanced, which is the characteristic infrared absorption of COC in cyclodextrin, indicating the presence of cyclodextrin in the CA / CD fiber membrane.

[0077] Figure 4 The thermogravimetric images of the CA membrane prepared in Example 1 and the CA / CD electrospun membrane prepared in Example 5 are shown in FIG. Figure 4 It can be seen that both the CA membrane and the CA / CD membrane begin to decompose at around 240°C, indicating that the CA membrane and the CA / CD membrane have good thermal stability.

[0078] Example 6

[0079] Among the prepared nanofiber membranes, a suitable fiber membrane is selected for filtration experiment, which includes the following steps:

[0080] After drying, the resulting fiber membranes were sprayed with gold to enhance conductivity. The membranes' micromorphology was then observed using a scanning electron microscope. Based on the SEM images, membranes with uniform fiber diameter and high porosity were selected for the next filtration experiment.

[0081] See attached figure Figure 1 CA nanofibers exhibited a relatively uniform size distribution and a distinct bead-like structure. Adding β-CD and HP-β-CD resulted in fiber accumulation, a spiderweb structure, and decreased interfiber pore size. Due to the improved solubility of hydroxypropyl-β-cyclodextrin in dimethylformamide, the CA / HP-β-CD membrane exhibited a looser interfiber arrangement, fewer surface droplets, and more uniform size. In the SBE-β-CD / CA membrane, the fibers were tightly packed, with a more uniform size and size distribution, and significantly fewer droplets and spiderweb structures. However, SBE-β-CD has poor solubility in dimethylformamide, and during spinning, the SBE-β-CD in the CA-SBE-β-CD mixed solution deposited on the syringe wall. Electrospinning with the addition of the three cyclodextrins to cellulose acetate in a ratio of 10:1:1:1 combined the good solubility of HP-β-CD and the improved conductivity of the spinning solution by SBE-β-CD, resulting in a nanofiber membrane with good fiber size and morphology.

[0082] Example 7

[0083] The adsorption effect of CA spun membrane and CA / CD spun membrane on nicotine. Including the following aspects:

[0084] Nicotine adsorption

[0085] use Figure 9 The device shown was used to conduct a nicotine filtration experiment in smoke. The four groups of filters were 125mg commercial Septwolves cigarette filter, 25mg CA spinning membrane (Example 1), 25mg CA / CD spinning membrane (Example 5) and a blank control group. After lighting the cigarette, under the action of the air pump, the air flow rate was 1L / min, and the cigarette smoke flowed through the filter and entered the collector containing 30mL of methanol, and was allowed to stand for 2 hours until it was completely absorbed. According to the literature, nicotine has ultraviolet absorption at 263nm, and the ultraviolet absorption of the methanol absorption solution at 263nm was measured. The results are as follows Figure 5 As shown, the filtration efficiency of each filter of equal mass was calculated, with the absorbance of the blank control group being 1. The nicotine filtration efficiency of the multi-component cyclodextrin complex / cellulose acetate membrane was 8 times that of commercial adsorbent materials.

[0086] Adsorption of other toxic compounds and PM particles

[0087] use Figure 9After the nicotine filtration experiment in smoke was conducted using the device shown, the membrane was air-dried and the added groups were qualitatively characterized using Fourier transform infrared spectroscopy. Figure 6 As shown by Figure 6 It can be seen that after filtering the flue gas, some absorption peaks are introduced into the infrared spectrum of the CA / CD membrane. -1 , 2886cm -1 , and 1731cm -1 The peaks corresponding to unsaturated hydrocarbons and aldehyde compounds. -1 Corresponding to aromatic hydrocarbons, 1357 cm -1 Corresponding to nitro compounds, these indicate that a large amount of toxic compounds are adsorbed into the CA / CD membrane. Elemental analysis was used to measure the added elements before and after filtration of the CA membrane and CA / CD membrane, and scanning electron microscopy was used to observe the changes in the microstructure of the membrane before and after filtration, such as Figure 7 As shown by Figure 7 It can be seen that the changes in the membrane morphology before and after adsorption indicate that both membranes adsorbed oil and particulate matter. Transmission electron microscopy observation of the difference in PM particle diameter after membrane filtration showed that Figure 8 As shown by Figure 8 It can be seen that the diameter of PM particles after CA / CD filtration is about 0.5 μm, which means that the CA / CD membrane can filter out PM particles with a diameter of more than 0.5 μm.

[0088] The above is only a preferred embodiment of the present invention. It should be pointed out that for ordinary technicians in this technical field, several improvements and modifications can be made without departing from the principles of the present invention. These improvements and modifications should also be regarded as the scope of protection of the present invention.

Claims

1. A nanofiber membrane based on a multi-component cyclodextrin complex and cellulose acetate, prepared by electrospinning a spinning solution. The spinning solution comprises cellulose acetate, cyclodextrin complex and dimethylformamide; The cyclodextrin complex includes sulfobutyl-β-cyclodextrin, β-cyclodextrin and hydroxypropyl-β-cyclodextrin.

2. The nanofiber membrane according to claim 1, characterized in that The mass ratio of the cellulose acetate and cyclodextrin complex is 0.5-1:0.15-0.

3.

3. The nanofiber membrane according to claim 1, characterized in that In the cyclodextrin complex, the mass ratio of sulfobutyl-β-cyclodextrin, β-cyclodextrin and hydroxypropyl-β-cyclodextrin is 0.05-0.1:0.05-0.1:0.05-0.

1.

4. The nanofiber membrane according to claim 1, characterized in that The fiber diameter of the nanofiber membrane based on the multi-component cyclodextrin complex and cellulose acetate is 100-200 nm.

5. The method for preparing a nanofiber membrane based on a multi-component cyclodextrin complex and cellulose acetate according to claim 1, comprising the following steps: A) dissolving the cellulose acetate and cyclodextrin complex in dimethylformamide, stirring and then ultrasonicating to obtain a spinning solution; B) electrospinning the spinning solution to obtain a nanofiber membrane.

6. The preparation method according to claim 5, characterized in that The stirring time in step A) is 3 to 6 hours; the ultrasonic time in step A) is 1 to 2 hours.

7. The preparation method according to claim 5, characterized in that The voltage of the electrostatic spinning is 25-30 kV, the propulsion speed of the propeller is 0.1-0.5 mm / min, the electrostatic spinning distance is 10-30 cm, and the rotation speed of the receiver is 200-600 rpm.

8. The preparation method according to claim 5, characterized in that The electrostatic spinning process further includes drying, wherein the drying temperature is 40 to 80° C. and the drying time is 8 to 12 hours.

9. Use of the nanofiber membrane based on the multi-component cyclodextrin complex and cellulose acetate as claimed in claim 1 in the preparation of cigarette filter materials.

10. The use according to claim 9, characterized in that The nanofiber membrane composed of a multi-component cyclodextrin complex and cellulose acetate is used for adsorbing nicotine and PM particles in cigarette smoke.

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