Aseptic sampling device

Abstract

The application discloses a sterile sampling device, which comprises a sampling needle and a support, a guide channel is arranged in the support, a first sealing element for sealing the guide channel is arranged at one end of the guide channel, the sampling needle is a hollow structure, one end of the sampling needle is arranged in the guide channel and is provided with a sampling hole, a needle tip part for puncturing the first sealing element is arranged at the end of the sampling needle arranged in the guide channel, a second sealing element is arranged between the support and the sampling needle, the sampling hole is arranged between the second sealing element and the first sealing element, a sampling channel is connected to the other end of the sampling needle, and a stop valve is arranged on the sampling channel. The application has the advantages of simple structure, reusability, and the like, and is favorable for avoiding the risks of liquid medicine pollution and waste.

Description

TECHNICAL FIELD

[0001] The present application relates to a sampling device used in food and drug production process, in particular to a sterile sampling device. BACKGROUND

[0002] In the drug production process, sterile sampling is an important step to effectively control microbial items. Although the disposable sampling device avoids the need for cleaning and sterilization, the price is generally higher, especially in the case of multiple sampling, which further increases the production cost of the manufacturer.

[0003] Patent document CN 204878996 U discloses a sterile sampling valve which can be reused after cleaning and sterilization, which is beneficial to reduce the production cost of the manufacturer. However, when the sampling valve is sampling, the sample first enters the sample chamber, and then is collected through the sampling port on the sample chamber. The structure is relatively complex, the drug in the sample chamber has the risk of pollution or waste, and after sampling, the handle needs to be operated again to seal the opening of the tank or pipeline, which is relatively cumbersome. SUMMARY

[0004] The technical problem to be solved by the present application is to overcome the shortcomings of the prior art and provide a sterile sampling device which is simple in structure, can be reused, and is beneficial to avoid the risk of liquid pollution and waste.

[0005] To solve the above technical problems, the following technical solutions are adopted in the present application:

[0006] A sterile sampling device, comprising a sampling needle and a support, the support is provided with a guide channel, one end of the guide channel is provided with a first sealing element for sealing the guide channel, the sampling needle is a hollow structure, one end of the sampling needle is located in the guide channel and is provided with a sampling hole, the end of the sampling needle located in the guide channel is provided with a needle tip portion for piercing the first sealing element, a second sealing element is arranged between the support and the sampling needle, the sampling hole is located between the second sealing element and the first sealing element, the other end of the sampling needle is connected with a sampling channel, and a stop valve is arranged on the sampling channel.

[0007] As a further improvement of the above technical solution, the support is provided with an elastic reset element, the sampling needle is provided with a first abutting portion, the support is provided with a second abutting portion, and the elastic reset element is arranged between the first abutting portion and the second abutting portion.

[0008] As a further improvement of the above technical solution, the elastic reset element is a spiral spring and is sleeved on the outer periphery of the sampling needle.

[0009] As a further improvement of the above technical solution: the support comprises a first part and a second part which is detachably connected with the first part, and the second sealing element is arranged at the connection between the first part and the second part.

[0010] As a further improvement of the above technical solution: the end of the sampling needle which is connected with the sampling channel is provided with a flange.

[0011] As a further improvement of the above technical solution: the support is provided with a plurality of guide channels in the circumferential direction, the sampling needle is provided with a plurality of sampling needles which are arranged one by one corresponding to the plurality of guide channels, and the support is rotatably arranged on a mounting base, and the mounting base is provided with a liquid inlet.

[0012] As a further improvement of the above technical solution: a detachable positioning assembly is arranged between the support and the mounting base.

[0013] As a further improvement of the above technical solution: the positioning assembly comprises a plurality of positioning grooves arranged in the circumferential direction of the support and a plurality of elastic pins arranged in the circumferential direction of the mounting base, and the plurality of elastic pins are positioned one by one in the plurality of positioning grooves.

[0014] As a further improvement of the above technical solution: a bearing is arranged between the support and the mounting base.

[0015] As a further improvement of the above technical solution: the support is detachably arranged on the mounting base.

[0016] Compared with the prior art, the sterile sampling device disclosed by the application has the following advantages: the sampling hole at one end of the sampling needle is located between the first sealing element and the second sealing element, so that a closed and sterile sampling flow channel can be formed inside the sampling needle; before sampling, the support is installed on the tank body or pipeline to be sampled, then the sampling needle pierces the first sealing element, and the liquid medicine can directly enter the sampling container through the sampling hole, the sampling needle and the sampling channel, after sampling is completed, the sampling needle is withdrawn, the first sealing element reseals the guide channel, the stop valve is closed, and the sampling container can be removed, the guide channel can provide a guide function for the reciprocating movement of the sampling needle to avoid deviation, the structure is simple, the sampling operation is convenient and fast, and it is beneficial to avoid the risk of liquid medicine pollution or waste; after the first sealing element is replaced and other components are cleaned and sterilized, the sterile sampling device can be repeatedly used, which is beneficial to reduce the cost and ensure that sterile sampling can still be realized when it is repeatedly used. BRIEF DESCRIPTION OF DRAWINGS

[0017] Figure 1 is a front view structural schematic diagram of the sterile sampling device according to the first embodiment of the application.

[0018] Figure 2is a structural schematic diagram of a first embodiment of the application installed on a tank body.

[0019] Figure 3 is a structural schematic diagram of a first embodiment of the application installed on a tank body.

[0020] Figure 4 is Figure 2 is an enlarged view of A in the figure.

[0021] Figure 5 is Figure 3 is an enlarged view of B in the figure.

[0022] Figure 6 is a front structural schematic diagram of a second embodiment of the sterile sampling device of the application.

[0023] Figure 7 is a side structural schematic diagram of a second embodiment of the sterile sampling device of the application.

[0024] The figures are as follows:

[0025] 100, tank body; 200, sampling container;

[0026] 1, sampling needle; 11, sampling hole; 12, first abutting portion; 13, flange; 2, support; 21, guide channel; 22, second abutting portion; 23, first part; 24, second part; 25, elastic reset member; 31, first sealing member; 32, second sealing member; 4, sampling channel; 41, stop valve; 5, mounting seat; 51, liquid inlet; 7, positioning assembly; 71, positioning groove; 72, elastic column pin; 8, bearing; 9, threaded fastener. DETAILED DESCRIPTION

[0027] In the description of the present application, it should be understood that the terms "length", "width", "upper", "lower", "front", "back", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer" and the like indicate the orientation or positional relationship based on the orientation or positional relationship shown in the drawings, and are only for the convenience of describing the present application and simplifying the description, and do not indicate or imply that the device or element referred to must have a particular orientation, be constructed and operated in a particular orientation, and therefore cannot be understood as a limitation of the present application.

[0028] In addition, the terms "first", "second" are only for descriptive purposes, and cannot be understood as indicating or implying relative importance or implicitly indicating the number of technical features indicated. Therefore, the features defined with "first", "second" can explicitly or implicitly include one or more of the features. In the description of the present application, the meaning of "multiple" is two or more, unless otherwise specifically limited.

[0029] In this application, unless specifically defined and limited otherwise, the terms "mounting", "connected", "connecting", "fixed", and the like, should be construed broadly and, for example, can be a fixed connection, or a detachable connection, or integral; can be a mechanical connection, or an electrical connection; can be a direct connection, or an indirect connection via an intermediate medium, or an internal communication of two elements, or an interaction relationship between two elements. For those skilled in the art, the specific meanings of the above terms in this application can be understood according to the specific circumstances.

[0030] The application will be further described in detail below in combination with the drawings and specific embodiments of the application.

[0031] Embodiment one

[0032] Figures 1 to 5 An embodiment of the sterile sampling device of the application is shown. The sterile sampling device of the embodiment comprises a sampling needle 1 and a support 2, the support 2 is provided with a guide channel 21, one end of the guide channel 21 is provided with a first sealing element 31 for sealing the guide channel 21, the sampling needle 1 is of a hollow structure, one end of the sampling needle 1 is located in the guide channel 21 and is provided with a sampling hole 11, the end of the sampling needle 1 located in the guide channel 21 is provided with a needle tip for piercing the first sealing element 31, a second sealing element 32 is arranged between the support 2 and the sampling needle 1, the sampling hole 11 is located between the second sealing element 32 and the first sealing element 31, the other end of the sampling needle 1 is connected with a sampling channel 4, and the sampling channel 4 is provided with a stop valve 41. Preferably, the first sealing element 31 is a sealing gasket, and the second sealing element 32 is a sealing ring, which are simple and reliable in structure and good in sealing performance.

[0033] The sterile sampling device of the embodiment can ensure that a closed and sterile sampling flow channel is formed inside the sampling needle 1, because the sampling hole 11 at one end of the sampling needle 1 is located between the first sealing element 31 and the second sealing element 32. Before sampling, the support 2 is mounted on a tank body 100 to be sampled, and preferably, the support 2 and the tank body 100 are connected by flanges and sealing elements are arranged at the contact parts of the two to ensure sealing. Of course, in other embodiments, the sterile sampling device of the embodiment can also be used for pipeline sampling. Then the sampling needle 1 pierces the first sealing element 31, and the liquid medicine can directly enter a sampling container 200 through the sampling hole 11, the sampling needle 1 and the sampling channel 4. After sampling is completed, the sampling needle 1 is withdrawn, the first sealing element 31 reseals the guide channel 21, the stop valve 41 is closed, and the sampling container 200 can be removed. The guide channel 21 can provide a guide function for the reciprocating movement of the sampling needle 1 to avoid deviation, and the structure is simple, the sampling operation is convenient and fast, and it is conducive to avoiding the risk of liquid medicine pollution or waste. After the first sealing element 31 is replaced and other parts are cleaned and sterilized, the sterile sampling device can be reused, which is conducive to reducing costs and ensuring that sterile sampling can still be achieved when it is reused.

[0034] Further, in the embodiment, the support 2 is provided with an elastic reset member 25, the sampling needle 1 is provided with a first abutting portion 12, the support 2 is provided with a second abutting portion 22, and the elastic reset member 25 is abutted between the first abutting portion 12 and the second abutting portion 22. See Figure 1 When sampling, the sampling needle 1 moves to the right to pierce the first sealing member 31, and at the same time, the elastic reset member 25 is compressed to produce a buffering effect; after sampling is completed, the elastic reset member 25 is stretched to drive the sampling needle 1 to automatically retreat to the left, and the use is more convenient.

[0035] As a preferred embodiment, the elastic reset member 25 is a spiral spring and is sleeved on the outer periphery of the sampling needle 1. The sampling needle 1 can provide a guide for the spiral spring, so that the spiral spring only deforms in extension and contraction, and the structure is simple and reliable. Of course, in other embodiments, the elastic reset member 25 can also be an elastic rope or an elastic block, and the like, which will not be described here.

[0036] Further, in the embodiment, the support 2 includes a first part 23 and a second part 24 which is detachably connected with the first part 23 (for example, the connection is achieved by buckling, flange or screw thread, etc.), and the second sealing member 32 is arranged at the connection between the first part 23 and the second part 24. After the connection between the first part 23 and the second part 24 is disassembled, the second sealing member 32 can be taken out or the installation of the second sealing member 32 is completed, and the structure is simple and reasonable.

[0037] As a preferred embodiment, the end of the sampling needle 1 connected with the sampling channel 4 is provided with a flange 13. The flange 13 can be used as a force point, and the operator can conveniently push the sampling needle 1 by means of the flange 13.

[0038] Embodiment two

[0039] Figures 6 to 7 Another embodiment of the sterile sampling device is shown, and the sterile sampling device of the embodiment is basically the same as that of embodiment one, and the difference lies in that:

[0040] In this embodiment, the support 2 is provided with a plurality of guide channels 21 in the circumferential direction, the sampling needle 1 is provided with a plurality of sampling needles corresponding to the plurality of guide channels 21, the support 2 is rotatably arranged on a mounting seat 5, and the mounting seat 5 is provided with a liquid inlet 51. Before sampling, the mounting seat 5 is installed on the tank 100 to be sampled, and preferably, the mounting seat 5 and the tank 100 are connected by flanges and a sealing element is arranged at the contact part of the two to ensure the sealing. The sampling method of a single sampling needle 1 is the same as that of the first embodiment, and the liquid enters the sampling hole 11 through the liquid inlet 51. When subsequent sampling is required, the support 2 is rotated so that the next guide channel 21 is aligned with the liquid inlet 51. Correspondingly, the sampling needle 1 and the first sealing element 31 in the guide channel 21 are also rotated and aligned with the liquid inlet 51. The sampling method can be repeated according to the first embodiment. When the support 2 rotates one circle, all the sampling needles 1 are used for sampling, and then the sterile sampling device is disassembled, the first sealing element 31 in each guide channel 21 is replaced, and the remaining parts are cleaned and sterilized for repeated use. The sterile sampling device of this embodiment has the advantages of simple and compact structure, convenient multiple sampling, and high efficiency of connection.

[0041] Further, in this embodiment, a detachable positioning assembly 7 is arranged between the support 2 and the mounting seat 5. When the support 2 is rotated, the positioning assembly 7 can be used to ensure that the guide channel 21 is accurately aligned with the liquid inlet 51, further improving the reliability.

[0042] As a preferred embodiment, the positioning assembly 7 includes a plurality of positioning grooves 71 arranged in the circumferential direction of the support 2 and a plurality of elastic column pins 72 arranged in the circumferential direction of the mounting seat 5, and the plurality of elastic column pins 72 are positioned in the plurality of positioning grooves 71 one by one. The operator applies force to the support 2, overcomes the resistance of the elastic column pin 72, and the elastic column pin 72 is separated from the positioning groove 71, and the support 2 can be rotated. When the positioning groove 71 is rotated to align with the next elastic column pin 72, the elastic column pin 72 is inserted into the positioning groove 71 again to realize positioning, and at this time the next guide channel 21 is aligned with the liquid inlet 51. The structure is simple, the operation is convenient, the positioning is accurate, each elastic column pin 72 can prevent the support 2 from rotating accidentally, and the reliability is good.

[0043] As a preferred embodiment, a bearing 8 is arranged between the support 2 and the mounting seat 5, which facilitates the rotation of the support 2 and the sampling needles 1 relative to the mounting seat 5, and the structure is simple and reliable.

[0044] Further, in the embodiment, the support 2 is detachably arranged on the mounting seat 5 (specifically, the support 2 is arranged on the mounting seat 5 through the threaded fastener 9, and the support 2 is prevented from moving along the axial direction of the mounting seat 5). The first part 23 can be separated from the mounting seat 5 by first removing the second part 24, and then removing the threaded fastener 9 and the elastic column pin 72, which is convenient to operate and suitable for aseptic operation.

[0045] Although the present application has been disclosed with reference to the preferred embodiments, it is not intended to limit the present application. Any person skilled in the art, without departing from the technical solution of the present application, can make many possible changes and modifications to the technical solution disclosed above, or modify equivalent embodiments with equivalent changes. Therefore, any simple modification, equivalent change and modification made to the above embodiments according to the technical essence of the present application, without departing from the content of the technical solution of the present application, shall fall within the protection scope of the technical solution of the present application.

Claims

1. A sterile sampling device, characterized in that: The device includes a sampling needle (1) and a support (2). The support (2) has a guide channel (21) inside. One end of the guide channel (21) is provided with a first sealing element (31) for sealing the guide channel (21). The sampling needle (1) is hollow. One end of the sampling needle (1) is located inside the guide channel (21) and is provided with a sampling hole (11). The end of the sampling needle (1) located inside the guide channel (21) is provided with a needle tip for piercing the first sealing element (31). A second sealing element (32) is provided between the support (2) and the sampling needle (1). The sampling hole (11) is located between the second sealing element (32) and the first sealing element (31). The other end of the sampling needle (1) is connected to a sampling channel (4). A stop valve (41) is provided on the sampling channel (4). The support (2) is provided with multiple guide channels (21) along the circumferential direction. The sampling needle (1) is provided with multiple needles and is arranged one-to-one with the multiple guide channels (21). The support (2) is rotatably mounted on a mounting base (5). The mounting base (5) is provided with a liquid inlet (51). A detachable positioning component (7) is provided between the support (2) and the mounting base (5). The positioning component (7) includes multiple positioning grooves (71) arranged along the circumferential direction of the support (2) and multiple elastic pins (72) arranged along the circumferential direction of the mounting base (5). The multiple elastic pins (72) are positioned one-to-one in the multiple positioning grooves (71). After sampling is completed, the sampling needle (1) retracts, and the first sealing element (31) can reseal the guide channel (21).

2. The aseptic sampling device according to claim 1, characterized in that: The support (2) is provided with an elastic reset member (25), the sampling needle (1) is provided with a first abutting part (12), the support (2) is provided with a second abutting part (22), and the elastic reset member (25) is abutted between the first abutting part (12) and the second abutting part (22).

3. The aseptic sampling device according to claim 2, characterized in that: The elastic reset element (25) is a helical spring and is sleeved on the outer periphery of the sampling needle (1).

4. The aseptic sampling device according to claim 1, characterized in that: The support (2) includes a first part (23) and a second part (24) detachably connected to the first part (23), and the second seal (32) is provided at the connection between the first part (23) and the second part (24).

5. The aseptic sampling device according to claim 1, characterized in that: The sampling needle (1) is connected to the sampling channel (4) at one end with a flange (13).

6. The aseptic sampling device according to any one of claims 1 to 5, characterized in that: A bearing (8) is provided between the support (2) and the mounting base (5).

7. The aseptic sampling device according to any one of claims 1 to 5, characterized in that: The support (2) is detachably mounted on the mounting base (5).

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