A urine sample test centrifuge processing system for implementing urine sediment separation
By designing a horizontal rotor centrifuge, the problem of easy adhesion of urine sediment in urine centrifuges was solved, achieving efficient separation and collection of urine sediment and supernatant, thus improving the accuracy and efficiency of testing.
Patent Information
- Application Number
- CN202310705247.2
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- Filing Date
- 2023-06-14
- Publication Date
- 2025-10-21
- Estimated Expiration
- 2043-06-14
AI Technical Summary
When existing urine centrifuges are used in a vertical position, urine sediment tends to adhere to the side wall of the test tube, making it difficult to separate the sediment from the liquid, affecting the accuracy of the test, and resulting in poor separation effect.
A horizontal rotor centrifuge is used, which uses a structure consisting of a corrosion-resistant rotating drum, a top cover turntable, and a wired rotor housing to achieve centrifugal separation of urine samples in a horizontal state. Combined with an electric liquid collector and a magnetic stirrer, it ensures the effective separation and collection of urine sediment and supernatant.
It achieves efficient separation of urine sediment and supernatant, prevents adhesion, improves the accuracy and efficiency of detection, can quickly collect and mix urine sediment, and is suitable for processing multiple urine samples simultaneously.
Smart Images

Figure CN116571361B_ABST
Abstract
Description
Technical Field
[0001] The invention relates to the technical field of horizontal rotor type centrifuges, in particular to a urine sample detection test centrifuge processing system for realizing urine sediment separation. Background Art
[0002] When performing urine sample centrifugation operations, a centrifuge is generally used for processing. During the operation, pour in the mixed fresh urine and wait for the centrifugation to stop. Then take out the centrifuge tube, discard the upper clear liquid, and leave the sediment to fully mix the visible components of the urine sediment. Take the urine sediment, drop it on a glass slide, cover it with a coverslip, and observe it under a microscope.
[0003] Currently, there are many types of centrifuges on the market, generally including inclined tube centrifuges, vertical tube centrifuges, and horizontal centrifuges. For example, the urine sediment centrifuge with patent publication number CN2514350Y has a main structure comprising a main shaft with power and motion input mounted on a base, a rotor mounted on the main shaft, and a protective shield surrounding the rotor and fixed to the base. The rotor is fitted with a test tube holder with a positioning device between the test tube holder and the rotor, and the test tube holder is provided with a set of holes for inserting urine test tubes. It may also be equipped with a device for aspirating clear urine from the test tube, which includes a gear mounted on the base, a column mounted in a column base with a rack at its bottom that can mesh with the gear, a crossbar mounted on the top of the column, a pipette holder with a urine clear liquid aspiration port connected to the crossbar, and a pipette mounted on the pipette holder above the hole.
[0004] It can be seen from the records of the above-mentioned prior art patent that the main shaft is mainly used to transmit power when performing urine sample centrifugation operations, and the various hole seats are mainly used to fix the urine sample test tubes when storing them. The urine sample test tubes are in a vertical state after installation. In this state, the centrifugal effect is poor when the urine sample is centrifuged, and the sediment is easy to adhere to the side wall of the test tube. When separating the supernatant and the urine sediment, it is easy to cause mixing of the sediment or loss of the sediment liquid, making it difficult to separate the sediment and the liquid, thereby affecting the accuracy of subsequent urine sediment detection.
[0005] For another example, the prior art also discloses a centrifuge for determining veterinary drug residues in urine with publication number CN217569176U and classification numbers B04B1 / 00 and B04B15 / 06. The centrifuge mainly drives the inner cylinder to rotate to centrifuge urine to separate the liquid and impurities in the urine. However, the separation effect of the centrifuge is relatively poor when separating impurities, and the centrifuge is unable to quickly collect and process the separated impurities.
[0006] In summary, the present invention optimizes and improves the problems existing in the urine sample centrifuge in the prior art, and hereby proposes a centrifuge that can maintain high-speed centrifugal treatment in a horizontal state to achieve solid-liquid sediment separation, so as to better solve the problems existing in the prior art. Summary of the Invention
[0007] The present invention solves one of the above technical problems, and the technical solution adopted is: a urine sample detection test centrifuge processing system for realizing urine sediment separation, comprising a chassis, a front door panel is fixedly mounted on the front side of the chassis, a top cover is fixedly mounted on the top of the chassis, a single door is hingedly mounted on the middle part of the front door panel by a hinge, an electric control box is mounted on the single door, a compartment inside the chassis is divided into an upper compartment and a lower compartment by a middle partition, a centrifugal drive assembly is mounted inside the lower compartment, a urine sample centrifugal storage assembly is mounted inside the upper compartment, an output end of the centrifugal drive assembly movably and sealedly passes through a through hole of the middle partition and is coaxially fixedly connected to the urine sample centrifugal storage assembly;
[0008] The urine sample centrifugal storage assembly includes an anti-corrosion rotor, the bottom center of the anti-corrosion rotor is fixedly connected to the output end of the centrifugal drive assembly, and an upper cover turntable is detachably fixedly installed on the top of the anti-corrosion rotor. A urine sample horizontal centrifugal mechanism, a first mixing mechanism, and a second mixing mechanism are respectively installed in the centrifugal main cavity of the anti-corrosion rotor.
[0009] In any of the above schemes, it is preferred that the urine sample horizontal centrifuge mechanism includes a routing rotor casing fixedly installed in the central part of the upper cover turntable, a urine separation unit is fixedly installed on the bottom of the routing rotor casing, and a urine sample storage group is respectively installed on the four side walls around the middle of the urine separation unit. Each of the urine sample storage groups is used to place a urine storage tube, and each of the urine storage tubes stores urine samples to be centrifuged, and the urine samples stored in each of the urine storage tubes are the same urine samples. When the urine separation unit is in the centrifugal working state, each of the urine storage tubes is in a horizontal centrifugal state.
[0010] In any of the above schemes, it is preferred that the urine separation unit includes a hollow horizontal rotor bin fixedly mounted on the bottom of the routing rotor casing, and electric liquid samplers cooperating with the urine sample storage groups at corresponding positions are fixedly mounted along the four sides of the bin body of the hollow horizontal rotor bin, and each of the electric liquid samplers is powered by a liquid collection mobile power supply fixed inside the hollow horizontal rotor bin, and the upper end of each electric liquid sampler is movably passed into the interior of the routing rotor casing and passed through the top center of the routing rotor casing to communicate and cooperate with the external liquid drawing tube group at the corresponding position.
[0011] In any of the above schemes, preferably, the urine sample storage unit includes two positioning ears that are relatively spaced and fixedly mounted on the outer side wall of the hollow horizontal rotor bin, a test tube storage tube is provided between the two positioning ears, both sides of the upper part of the test tube storage tube are movably inserted into the rotating holes of the positioning ears at corresponding positions through fixed rotating shafts, a urine storage test tube is installed in the sample storage cavity of the test tube storage tube, the urine storage test tube includes a test tube body, a urine sample is stored in the interior of the test tube body, a sealing cover is sealed at the mouth of the test tube body, and a spring-loaded one-way valve is fixedly mounted at the center of the outer end of the sealing cover, and the spring-loaded one-way valve can only be pressed from the outside to the inside of the test tube body to achieve conduction;
[0012] Each of the test tube storage tubes is in a vertical state in an idle state and in a horizontal state in a centrifugal state.
[0013] In any of the above schemes, it is preferred that when the electric liquid sampler at the corresponding position is started, the spring-loaded one-way valve is connected to the spring-loaded one-way valve and is used to quantitatively suck out the urine supernatant inside the urine storage tube in a horizontal centrifugal state, and retain the urine sediment at the far end of the urine storage tube.
[0014] In any of the above schemes, it is preferred that the electric liquid sampler includes a micro-electric cylinder fixedly mounted inside the chamber body of the hollow horizontal rotor chamber, the outer end of the micro-electric cylinder extends to the outside of the hollow horizontal rotor chamber and the electric liquid sampler is fixedly mounted on the end of its piston rod; the electric liquid sampler includes a sealed outer tube sleeve fixedly mounted on the end of the piston rod of the micro-electric cylinder and with an inner end sealed, the sealed outer tube sleeve is used to achieve a sealed socket connection with the outer side wall of the spring-type one-way valve at the corresponding position, a central pushing shaft is fixedly mounted at the center of the cavity of the sealed outer tube sleeve, when the micro-electric cylinder drives the sealed outer tube sleeve toward the spring-type one-way valve for socket connection, the central pushing shaft pushes open the valve ball inside the spring-type one-way valve and realizes the conduction of the spring-type one-way valve, the inner valve tube end of the spring-type one-way valve extends to the preset length of the test tube body and can be telescopically adjusted as needed.
[0015] In any of the above schemes, it is preferred that a liquid-conducting telescopic pipeline is connected to the top outlet end of each of the sealed outer tube sleeves, the upper part of each of the liquid-conducting telescopic pipelines extends to the interior of the routing rotor housing and is connected to a rigid vertical pipe, and a micro pump body is installed on each of the liquid-conducting telescopic pipelines. The top of the rigid vertical pipe passes through the routing rotor housing and the top center of the top cover and is connected to and cooperates with the external liquid-drawing tube group at the corresponding position.
[0016] In any of the above schemes, it is preferred that the external liquid drawing tube group includes a fixing frame fixedly installed on the top of the top cover, and a rigid drawing elbow is fixedly installed in the center of the fixing frame, and the vertical pipe section of the rigid drawing elbow is movable and sealed on the outer side wall of the rigid riser.
[0017] In any of the above schemes, preferably, the first mixing mechanism includes a plurality of static position vertical cylinders respectively fixedly installed at the bottom of the centrifugal main chamber below each of the test tube storage tubes in the vertical state, and a static position magnetic stirrer is fixedly installed on the top of the piston rod of the static position vertical cylinder, and each of the static position magnetic stirrers has two working positions when in operation;
[0018] In the first working position, the static magnetic stirrer is located below the corresponding test tube storage tube in the vertical state and after being started, it fully stirs and mixes the urine sediment mixture remaining at the bottom of the urine sample inside the urine storage tube;
[0019] In the second working position, the static magnetic stirrer serves as a lifting member and is in a shutdown state to support the test tube storage tube in a high-speed centrifugal state at a corresponding position and ensure that the test tube storage tube is in a horizontal state.
[0020] In any of the above schemes, preferably, a stirring power supply is fixedly installed at the bottom of the centrifugal main cavity on both sides of the first mixing mechanism, and the stirring power supply is used to supply power to the first mixing mechanism and the second mixing mechanism.
[0021] In any of the above schemes, it is preferred that the second mixing mechanism includes a number of horizontal centrifugal electric cylinders that are evenly and spaced apart along the circumferential direction of the anti-corrosion drum, the cylinder barrel of each of the horizontal centrifugal electric cylinders is fixedly mounted on the upper outer wall of the anti-corrosion drum, the inner end of the piston rod of each of the horizontal centrifugal electric cylinders is movable through the through hole at the corresponding position and extends into the centrifugal main cavity of the anti-corrosion drum, the inner end of the piston rod of each of the horizontal centrifugal electric cylinders is fixed with a horizontal centrifugal magnetic stirrer, and each of the horizontal centrifugal magnetic stirrers is coaxially arranged with the test tube storage tube in the horizontal centrifugal state at the corresponding position.
[0022] In any of the above schemes, preferably, the centrifugal drive assembly includes a centrifugal motor fixedly mounted on the bottom of the lower chamber, a belt transmission member is mounted on the output shaft of the centrifugal motor, a vertical shaft support bearing seat is movably mounted on the bottom of the central axis of the driven pulley of the belt transmission member, the bottom of the vertical shaft support bearing seat is fixedly arranged, and the top of the central axis of the driven pulley of the belt transmission member is movably extended to the interior of the upper chamber and fixedly connected to the bottom center of the anti-corrosion drum;
[0023] A supporting steel ball is movably clamped in each clamping groove at the bottom of the anti-corrosion drum, and the bottom of each supporting steel ball is supported on the top of the middle partition.
[0024] In any of the above solutions, preferably, a push armrest is fixedly mounted on the upper outer side walls of the left and right sides of the chassis respectively;
[0025] Universal wheel sets with brakes are fixedly installed at the four corners of the bottom of the chassis.
[0026] In any of the above solutions, preferably, a lifting support assembly is fixedly mounted on the bottom of the chassis on the inner side of each universal wheel assembly.
[0027] In any of the above schemes, it is preferred that the lifting support assembly includes a vertical internal screw tube fixedly installed on the bottom of the chassis, an internal thread is provided in the inner cavity of the vertical internal screw tube, an external thread support column is screwed into the internal thread of the inner cavity of the vertical internal screw tube, an external thread is provided on the outer wall of the external thread support column, and a support foot is fixedly installed on the bottom of the external thread support column, and the support foot is supported on the ground in the working state and is higher than the ground in the idle state.
[0028] Compared with the prior art, the present invention has the following beneficial effects:
[0029] 1. When the centrifuge processing system is in fixed-axis operation, it relies on the driving centrifugal drive assembly to achieve fixed-axis rotation. At the same time, it relies on the mutually fixed anti-corrosion rotor, upper cover turntable, wiring rotor casing, and hollow horizontal rotor chamber to form a structure equivalent to the function of a horizontal rotor for centrifugal rotation, which is convenient for horizontal centrifugation of urine samples in each test tube to separate liquid and residue, and prevent the urine sediment at the far end of the centrifuge from adhering to the inner wall of the middle section of the test tube.
[0030] 2. It is used to achieve precise centrifugal separation of the same urine sample. The uniform centrifugation method of test tubes can simultaneously realize the centrifugal treatment of the residue and liquid of multiple urine samples from the same urine source under the same centrifugal conditions, thereby realizing the separation of urine sediment; multiple groups of urine samples can simultaneously use centrifugal force to achieve liquid and residue centrifugation to better separate urine sediment. The separation effect of urine sediment is relatively good, and the separated urine sediment can be quickly collected and mixed.
[0031] 3. The centrifuge processing system uses a set speed when processing urine samples (during centrifugation, take 10mL-15mL of fresh urine sample liquid and place it in the urine storage test tube in advance, and put the urine storage test tube in place. After storage and installation, start the centrifuge and perform centrifugal treatment for 5 minutes. The speed is controlled at 1500r / min. After centrifugation is completed, the supernatant and urine sediment are distributed in different positions in the test tube). During centrifugation, it can effectively ensure that the urine sample is in a horizontal state for centrifugation, and can effectively ensure that the urine sediment with heavier weight and density is concentrated at the far end of the urine storage test tube and the supernatant is concentrated at the proximal end of the urine storage test tube under the centrifugal state, ensuring the boundary effect of the residue and liquid, and ensuring the centrifugal precipitation effect of the urine sediment inside the urine sample.
[0032] 4. The centrifuge processing system designed in the present invention has two modes for separating urine from urine sediment. The first is centrifugation and simultaneous separation and extraction of urine sediment: this method can be selected as needed to directly complete the separation of the supernatant urine in the centrifugal state and aspirate it out so that only urine sediment and an appropriate amount of urine exist in the test tube, thereby improving the efficiency of urine sample centrifugation and urine sediment extraction; the second is centrifugation and resetting and standing after the centrifugation is completed, waiting for the supernatant to be layered and then manually aspirating the supernatant to complete the collection of urine sediment. Selecting two methods as needed can better ensure the centrifugal collection effect of urine sediment. BRIEF DESCRIPTION OF THE DRAWINGS
[0033] To more clearly illustrate the specific embodiments of the present invention or the technical solutions in the prior art, the following briefly describes the drawings required for the specific embodiments or the description of the prior art. Similar elements or components are generally identified by similar reference numerals throughout the drawings. Elements or components in the drawings are not necessarily drawn to scale.
[0034] Figure 1 It is a schematic diagram of the main structure of the present invention.
[0035] Figure 2 This is a schematic diagram of the internal structure of the urine storage tube of the present invention after placement.
[0036] Figure 3 It is a schematic structural diagram of each urine storage tube of the present invention in a state of starting to rotate centrifuge.
[0037] Figure 4 It is a schematic structural diagram of each urine storage tube of the present invention in a horizontal centrifugal state.
[0038] Figure 5 It is a schematic top view of the partial structure inside the urine sample centrifugal storage assembly of the present invention.
[0039] Figure 6 For the present invention Figure 5 Schematic diagram of the partial cross-section structure.
[0040] Figure 7 It is a schematic structural diagram of the relative states of the spring-type one-way valve of the present invention and the electric liquid sampler at the corresponding position.
[0041] In the figure, 1. chassis; 2. front door panel; 3. top cover; 4. single door; 5. electric control box; 6. middle partition; 7. upper chamber; 8. lower chamber; 9. anti-corrosion drum; 10. upper cover turntable; 11. centrifugal main chamber; 12. routing rotor housing; 13. urine storage tube; 14. hollow horizontal rotor chamber; 15. mobile power supply for liquid collection; 16. positioning ear seat; 17. test tube storage tube; 18. fixed shaft; 19. support foot; 20. test tube body; 21. sealing cover; 22. spring-loaded one-way valve; 2201, inner valve tube end; 23. micro electric cylinder; 24. sealed outer tube sleeve ; 25. Center push shaft; 26. Valve ball; 27. Liquid guide telescopic pipe; 28. Rigid vertical pipe; 29. Micro pump body; 30. Fixed frame; 31. Rigid suction elbow; 32. Static position vertical cylinder; 33. Static position magnetic stirrer; 34. Stirring power supply; 35. Horizontal centrifugal position electric cylinder; 36. Horizontal centrifugal position magnetic stirrer; 37. Centrifugal motor; 38. Belt transmission; 3801. Driven pulley; 39. Vertical shaft support bearing seat; 40. Support steel ball; 41. Side push handrail; 42. Universal wheel set; 43. Vertical internal screw tube; 44. External thread support column. DETAILED DESCRIPTION
[0042] The following embodiments of the technical solution of the present invention are described in detail with reference to the accompanying drawings. The following embodiments are only used to more clearly illustrate the technical solution of the present invention and are therefore only used as examples and are not intended to limit the scope of protection of the present invention. Figure 1-Figure 7 As shown in .
[0043] Example 1: A urine sample detection test centrifuge processing system for separating urine sediment, comprising a chassis 1, a front door panel 2 fixedly mounted on the front side of the chassis 1, a top cover 3 detachably mounted on the top of the chassis 1, a single door 4 hingedly mounted in the middle of the front door panel 2, an electric control box 5 mounted on the single door 4, a compartment inside the chassis 1 is divided into an upper compartment 7 and a lower compartment 8 by a middle partition 6, a centrifugal drive assembly is mounted inside the lower compartment 8, and a centrifugal drive assembly is mounted inside the upper compartment 7. It is equipped with a urine sample centrifugal storage assembly, the output end of the centrifugal drive assembly is used to move and seal through the through hole on the middle partition 6 and is coaxially fixedly connected to the urine sample centrifugal storage assembly; the urine sample centrifugal storage assembly includes an anti-corrosion rotor 9, the bottom center of the anti-corrosion rotor 9 is fixedly connected to the output end of the centrifugal drive assembly, and an upper cover turntable 10 is detachably fixedly installed on the top of the anti-corrosion rotor 9. The urine sample horizontal centrifugal mechanism, the first mixing mechanism, and the second mixing mechanism are respectively installed in the centrifugal main cavity 11 of the anti-corrosion rotor 9.
[0044] The urine sample detection test centrifuge processing system for realizing urine sediment separation in the present invention adopts a structure that is easy to move as a whole, can be flexibly moved when in use and can be stably positioned when needed.
[0045] The entire system relies on the centrifugal drive assembly to achieve high-speed centrifugal operation of the entire urine sample centrifugal storage assembly, thereby effectively ensuring the high-speed rotation of the anti-corrosion drum 9 and its internal components. During the high-speed rotation process, it is necessary to control the set speed to achieve the operation of centrifugal precipitation of urine sediment at an appropriate speed for the multiple tube urine samples stored inside. During the centrifugal operation, the second mixing mechanism can be used to achieve sufficient mixing of the urine samples at each position. At the same time, after the centrifugal operation is completed, the first mixing mechanism can also be used to achieve mixing of the urine samples at the corresponding positions, effectively ensuring the treatment effect of the urine samples.
[0046] In any of the above schemes, it is preferred that the urine sample horizontal centrifuge mechanism includes a routing rotor casing 12 fixedly mounted on the central part of the upper cover turntable 10, a urine separation unit is fixedly mounted on the bottom of the routing rotor casing 12, and a urine sample storage group is respectively mounted on the four side walls around the middle of the urine separation unit, each of the urine sample storage groups is used to place a urine storage test tube 13, each of the urine storage test tubes 13 stores urine samples to be centrifuged, and the urine samples stored in each of the urine storage test tubes 13 are the same urine samples, and when the urine separation unit is in the centrifugal working state, each of the urine storage test tubes 13 is in a horizontal centrifugal state. When the urine sample horizontal centrifuge mechanism is working, each urine sample storage unit can be used to store urine storage test tubes 13 containing urine samples. When each urine storage test tube 13 follows the anti-corrosion rotating drum 9 to rotate at high speed, it will gradually transform from a vertical state to a nearly horizontal state under the state of centrifugal force, until it reaches a horizontal state. Centrifugation in a horizontal state can better ensure that the urine sediment with higher density is precipitated to the far end of the test tube under the action of centrifugal force, thereby improving the separation effect, preventing the urine sediment from adhering to the middle side wall of the test tube, and ensuring the precipitation rate of the urine sediment.
[0047] In any of the above-mentioned embodiments, the urine separation unit preferably includes a hollow horizontal rotor chamber 14 fixedly mounted at the bottom of the routing rotor housing 12. Within the hollow horizontal rotor chamber 14, electric liquid collectors are fixedly mounted along its periphery, each corresponding to the urine sample storage assembly. Each electric liquid collector is powered by a mobile liquid collection power supply 15 fixed within the hollow horizontal rotor chamber 14. The upper end of each electric liquid collector is movable through the interior of the routing rotor housing 12 and out through the top center of the routing rotor housing 12, where it is connected to the external liquid collection tube assembly at the corresponding position. In the idle state, the urine separation unit is not in contact with the urine storage tube 13 at the corresponding position. When the urine separation unit needs to be controlled to aspirate urine from the proximal end of each urine storage tube 13, the corresponding electric liquid collector can be controlled to move and sealably engage with the spring-loaded one-way valve 22 at the end of each urine storage tube 13 to achieve communication with the interior of the urine storage tube 13.
[0048] In any of the above schemes, it is preferred that the urine sample storage unit includes two positioning ear seats 16 that are relatively spaced and fixedly mounted on the outer side wall of the hollow horizontal rotor bin 14, and a test tube storage tube 17 is arranged between the two positioning ear seats 16. The upper two sides of the test tube storage tube 17 are movably inserted into the rotating holes of the positioning ear seats 16 at corresponding positions through fixed rotating shafts 18, and a urine storage test tube 13 is installed in the sample storage cavity of the test tube storage tube 17, and the urine storage test tube 13 includes a test tube body 20, in which urine sample is stored, and a sealing cover 21 is sealedly mounted at the mouth of the test tube body 20, and a spring-loaded one-way valve 22 is fixedly mounted at the outer end center of the sealing cover 21, and the spring-loaded one-way valve 22 can only be pressed from the outside to the inside of the test tube body 20 to achieve conduction; each of the test tube storage tubes 17 is in a vertical state in an idle state and in a horizontal state in a centrifugal state. Before centrifugation, the corresponding urine storage test tubes 13 containing the same urine sample need to be placed in the sample storage cavity of the corresponding test tube storage tube 17. At this time, each urine storage test tube 13 is in a vertical state, and will gradually transform into a horizontal state when centrifugal rotation begins.
[0049] In any of the above schemes, preferably, the first mixing mechanism includes a plurality of static position vertical cylinders 32 respectively fixedly installed at the bottom of the centrifugal main chamber 11 below the test tube storage tube 17 in the vertical state, and a static position magnetic stirrer 33 is fixedly installed on the top of the piston rod of the static position vertical cylinder 32. Each of the static position magnetic stirrers 33 has two working positions when in operation;
[0050] In the first working position, the static magnetic stirrer 33 is located below the corresponding test tube storage tube 17 in the vertical state and after being started, it fully stirs and mixes the urine sediment mixture remaining at the bottom of the urine sample inside the urine storage test tube 13;
[0051] In the second working position, the static magnetic stirrer 33 acts as a lifting member and is in the off state to support the test tube storage tube 17 in the high-speed centrifugal state at the corresponding position and ensure that the test tube storage tube 17 is in a horizontal state. Before the first mixing mechanism is activated, the urine sample is first centrifuged and the supernatant and urine are separated and removed after standing. When only the urine sediment mixture exists in the test tube, the magnetic stirrer 33 in each static position of the first mixing mechanism is activated to quickly mix the urine sediment in each urine storage test tube 13. After mixing, it is convenient for subsequent urine sediment to be aspirated and sent for microscopic examination.
[0052] In any of the above schemes, preferably, a stirring power supply 34 is fixedly installed at the bottom of the centrifugal main chamber 11 on both sides of the first mixing mechanism, and the stirring power supply 34 is used to supply power to the first mixing mechanism and the second mixing mechanism.
[0053] In any of the above schemes, it is preferred that the second mixing mechanism includes a number of horizontal centrifugal electric cylinders 35 that are evenly and spaced apart along the circumferential direction of the anti-corrosion drum 9, and the cylinder barrel of each of the horizontal centrifugal electric cylinders 35 is fixedly mounted on the upper outer wall of the anti-corrosion drum 9. The inner end of the piston rod of each of the horizontal centrifugal electric cylinders 35 moves through the through hole at the corresponding position and extends into the centrifugal main cavity 11 of the anti-corrosion drum 9. The inner end of the piston rod of each of the horizontal centrifugal electric cylinders 35 is fixed with a horizontal centrifugal magnetic stirrer 36, and each of the horizontal centrifugal magnetic stirrers 36 is coaxially arranged with the test tube storage tube 17 in a horizontal centrifugal state at the corresponding position.
[0054] In any of the above schemes, it is preferred that the centrifugal drive assembly includes a centrifugal motor 37 fixedly mounted on the bottom of the lower chamber 8, and a belt transmission member 38 is installed on the output shaft of the centrifugal motor 37. The bottom of the central axis of the driven pulley 3801 of the belt transmission member 38 is movably fitted with a vertical shaft support bearing seat 39, and the bottom of the vertical shaft support bearing seat 39 is fixedly arranged, and the top of the central axis of the driven pulley 3801 of the belt transmission member 38 is movably extended to the interior of the upper chamber 7 and is fixedly connected to the bottom center of the anti-corrosion drum 9; when the centrifugal drive assembly is working, it relies on the centrifugal motor 37 and the belt transmission member 38 to realize the drive of rotational power, thereby ensuring the centrifugal effect and efficiency during centrifugal treatment.
[0055] A supporting steel ball 40 is movably engaged in each slot at the bottom of the anti-corrosion drum 9, and the bottom of each supporting steel ball 40 is supported on the top of the middle partition 6. During the centrifugal rotation, the operation of the supporting steel ball 40 can effectively play the role of support and guidance.
[0056] In any of the above solutions, preferably, a side push arm 41 is fixedly mounted on the upper outer walls of the left and right sides of the chassis 1, and a universal wheel set 42 with brakes is fixedly mounted at the four corners of the bottom of the chassis 1. The entire system can be easily moved and flexibly transferred by relying on the universal wheel set 42. At the same time, the side push arm 41 can be used to effectively push the machine during movement, facilitating the application of force.
[0057] In any of the above schemes, preferably, a lifting support assembly is fixedly mounted on the bottom of the chassis 1 on the inner side of each universal wheel assembly 42; the lifting support assembly includes a vertical internal screw 43 fixedly mounted on the bottom of the chassis 1, the inner cavity of the vertical internal screw 43 is provided with an internal thread, an external thread support column 44 is screwed into the inner thread of the inner cavity of the vertical internal screw 43, the outer wall of the external thread support column 44 is provided with an external thread, and a support foot 19 is fixedly mounted on the bottom of the external thread support column 44, the support foot 19 is supported on the ground in the working state and is higher than the ground in the idle state. When the entire system needs to be stable, the height of the support foot 19 can be adjusted by operating each lifting support assembly. During adjustment, rotating the support foot 19 can drive the corresponding external thread support column 44 to rotate and lift, thereby controlling the external thread support column 44 to drive the support foot 19 at its bottom to move downward and support it on the ground.
[0058] Example 2: A urine sample detection test centrifuge processing system for realizing urine sediment separation, comprising a chassis 1, a front door panel 2 being fixedly mounted on the front side of the chassis 1, a top cover 3 being detachably fixedly mounted on the top of the chassis 1, a single door 4 being hingedly mounted in the middle of the front door panel 2 by a hinge, an electric control box 5 being mounted on the single door 4, a compartment inside the chassis 1 being divided into an upper chamber 7 and a lower chamber 8 by a middle partition 6, a centrifugal drive assembly being mounted inside the lower chamber 8, a urine sample centrifugal storage assembly being mounted inside the upper chamber 7, an output end of the centrifugal drive assembly being adapted to move and seal through a through hole on the middle partition 6 and being coaxially fixedly connected to the urine sample centrifugal storage assembly;
[0059] The urine sample centrifugal storage assembly includes an anti-corrosion drum 9, the bottom center of the anti-corrosion drum 9 is fixedly connected to the output end of the centrifugal drive assembly, and an upper cover turntable 10 is detachably fixedly installed on the top of the anti-corrosion drum 9. The urine sample horizontal centrifugal mechanism, the first mixing mechanism, and the second mixing mechanism are respectively installed in the centrifugal main cavity 11 of the anti-corrosion drum 9.
[0060] In any of the above schemes, it is preferred that the urine sample horizontal centrifuge mechanism includes a routing rotor casing 12 fixedly mounted on the central part of the upper cover turntable 10, a urine separation unit is fixedly mounted on the bottom of the routing rotor casing 12, and a urine sample storage group is respectively mounted on the four side walls around the middle of the urine separation unit, each of the urine sample storage groups is used to place a urine storage test tube 13, each of the urine storage test tubes 13 stores urine samples to be centrifuged, and the urine samples stored in each of the urine storage test tubes 13 are the same urine samples, and when the urine separation unit is in the centrifugal working state, each of the urine storage test tubes 13 is in a horizontal centrifugal state.
[0061] When the urine sample horizontal centrifuge mechanism is working, each urine sample storage unit can be used to store urine storage test tubes 13 containing urine samples. When each urine storage test tube 13 follows the anti-corrosion rotating drum 9 to rotate at high speed, it will gradually transform from a vertical state to a nearly horizontal state under the state of centrifugal force, until it reaches a horizontal state. Centrifugation in a horizontal state can better ensure that the urine sediment with higher density is precipitated to the far end of the test tube under the action of centrifugal force, thereby improving the separation effect, preventing the urine sediment from adhering to the middle side wall of the test tube, and ensuring the precipitation rate of the urine sediment.
[0062] In the centrifugal state, in order to improve the efficiency of the operation, the operation of the urine separation unit can be controlled to separate the supernatant urine at the proximal end of the test tube by centrifugal force and be sucked outwards under the action of the pump body. At the same time, after being sucked out, the urine sediment mixed liquid is retained at the distal end of the test tube to ensure the efficiency and effect of the separation of sediment and liquid. The separated and sucked urine can be transported to the outside for collection through the pipeline.
[0063] In any of the above schemes, it is preferred that the urine separation unit includes a hollow horizontal rotor bin 14 fixedly mounted on the bottom of the routing rotor casing 12, and electric liquid samplers cooperating with the urine sample storage groups at corresponding positions are fixedly mounted along the four sides of the bin body of the hollow horizontal rotor bin 14. Each of the electric liquid samplers is powered by a liquid collection mobile power supply 15 fixed inside the hollow horizontal rotor bin 14, and the upper end of each electric liquid sampler is movably passed into the interior of the routing rotor casing 12 and passed through the top center of the routing rotor casing 12 to communicate and cooperate with the external liquid drawing tube group at the corresponding position.
[0064] When the urine separation unit is in an idle state, it is not in contact with the urine storage test tube 13 at the corresponding position. When it is necessary to control the urine separation unit to suck out the urine from the proximal end of each urine storage test tube 13, the corresponding electric liquid sampler can be controlled to move and seal with the spring-loaded one-way valve 22 at the end of each urine storage test tube 13 to achieve the purpose of communicating with the interior of the urine storage test tube 13.
[0065] When each spring-loaded one-way valve 22 is matched with the corresponding electric liquid sampler, the pump body inside each routing rotor housing 12 is started to suck out the supernatant urine at the proximal end of the corresponding urine storage test tube 13 in a centrifugal state. After suction, only a small amount of urine and all the urine sediment are retained in each test tube, which is convenient for later observation and detection of the urine sediment under a microscope.
[0066] In any of the above schemes, it is preferred that the urine sample storage unit includes two positioning ear seats 16 that are relatively spaced and fixedly mounted on the outer side wall of the hollow horizontal rotor bin 14, a test tube storage tube 17 is provided between the two positioning ear seats 16, and the upper two sides of the test tube storage tube 17 are movably inserted into the rotating holes of the positioning ear seats 16 at corresponding positions through fixed rotating shafts 18, a urine storage test tube 13 is installed in the sample storage cavity of the test tube storage tube 17, the urine storage test tube 13 includes a test tube body 20, a urine sample is stored in the interior of the test tube body 20, a sealing cover 21 is sealed at the mouth of the test tube body 20, and a spring-loaded one-way valve 22 is fixedly mounted at the center of the outer end of the sealing cover 21, and the spring-loaded one-way valve 22 can only be pressed from the outside to the inside of the test tube body 20 to achieve conduction;
[0067] Each of the test tube storage tubes 17 is in a vertical state when in an idle state and in a horizontal state when in a centrifugal state.
[0068] Before centrifugation, the corresponding urine storage test tubes 13 containing the same urine sample need to be placed in the sample storage cavity of the corresponding test tube storage tube 17. At this time, each urine storage test tube 13 is in a vertical state, and will gradually transform into a horizontal state when centrifugal rotation begins.
[0069] In any of the above schemes, it is preferred that when the electric liquid sampler at the corresponding position is started, the spring-loaded one-way valve 22 is connected to the spring-loaded one-way valve 22 and is used to quantitatively suck out the urine supernatant inside the urine storage tube 13 in a horizontal centrifugal state, and retain the urine sediment at the distal end of the urine storage tube 13.
[0070] In any of the above schemes, it is preferred that the electric liquid sampler includes a micro-electric cylinder 23 fixedly mounted inside the chamber body of the hollow horizontal rotor chamber 14, the outer end of the micro-electric cylinder 23 extends to the outside of the hollow horizontal rotor chamber 14 and the electric liquid sampler is fixedly mounted on the end of its piston rod; the electric liquid sampler includes a sealed outer tube sleeve 24 fixedly mounted on the end of the piston rod of the micro-electric cylinder 23 and with the inner end sealed, the sealed outer tube sleeve 24 is used to communicate with the spring-type one-way valve at the corresponding position The outer wall of the sealing outer tube sleeve 22 is sealed and sleeved, and a central pushing shaft 25 is fixedly installed in the center of the cavity of the sealing outer tube sleeve 24. When the micro-electric cylinder 23 drives the sealing outer tube sleeve 24 to sleeve toward the spring-type one-way valve 22, the central pushing shaft 25 pushes open the valve ball 26 inside the spring-type one-way valve 22 and realizes the conduction of the spring-type one-way valve 22. The inner valve tube end 2201 of the spring-type one-way valve 22 extends to the preset length of the test tube body 20 and can be telescopically adjusted as needed.
[0071] When the electric liquid sampler works, it mainly relies on the expansion and contraction of the micro-electric cylinder 23 to drive the corresponding sealed outer tube sleeve 24 to move toward the spring-type one-way valve 22 on the corresponding side, so that the movable sealing sleeve is connected to the outer side wall of the spring-type one-way valve 22 under the action of the thrust of the electric cylinder. At the same time, the valve ball 26 inside the spring-type one-way valve 22 can be pushed open by relying on the central pushing shaft 25. At this time, starting the micro-pump body 29 can quickly suck out the urine inside the test tube.
[0072] In any of the above schemes, it is preferred that a liquid-conducting telescopic pipe 27 is connected to the top outlet end of each of the sealed outer tube sleeves 24, the upper part of each of the liquid-conducting telescopic pipes 27 extends to the interior of the routing rotor housing 12 and is connected to a rigid standpipe 28, and a micro pump body 29 is installed on each of the liquid-conducting telescopic pipes 27. The top of the rigid standpipe 28 passes through the routing rotor housing 12 and the top center of the top cover 3 and is connected to and cooperates with the external liquid-drawing pipe group at the corresponding position.
[0073] The micro pump body 29 can play a role of power suction when it works. By controlling the working efficiency of the micro pump body 29 , the urine samples in each test tube can be drained out, thereby completing the separation of the supernatant urine and the urine sediment under the centrifugal state.
[0074] In any of the above schemes, it is preferred that the external liquid drawing tube group includes a fixing frame 30 fixedly installed on the top of the top cover 3, and a rigid drawing bend 31 is fixedly installed in the center of the fixing frame 30, and the vertical pipe section of the rigid drawing bend 31 is movable and sealed on the outer wall of the rigid riser 28.
[0075] The rigid extraction elbow 31 is in a fixed state during operation, and the rigid standpipe 28 with movable sealing at its lower end adopts a movable sealing method to ensure that relative movement and sealing can be achieved, thereby ensuring the effect of sucking out urine.
[0076] In any of the above schemes, preferably, the first mixing mechanism includes a plurality of static position vertical cylinders 32 respectively fixedly installed at the bottom of the centrifugal main chamber 11 below the test tube storage tube 17 in the vertical state, and a static position magnetic stirrer 33 is fixedly installed on the top of the piston rod of the static position vertical cylinder 32. Each of the static position magnetic stirrers 33 has two working positions when in operation;
[0077] In the first working position, the static magnetic stirrer 33 is located below the corresponding test tube storage tube 17 in the vertical state and after being started, it fully stirs and mixes the urine sediment mixture remaining at the bottom of the urine sample inside the urine storage test tube 13;
[0078] In the second working position, the static magnetic stirrer 33 serves as a lifting member and is in the off state to support the test tube storage tube 17 in the high-speed centrifugal state at the corresponding position and ensure that the test tube storage tube 17 is in a horizontal state.
[0079] Before the first mixing mechanism works, the urine sample is first centrifuged, and the supernatant urine is separated and removed after standing. When only the urine sediment mixture exists inside the test tube, the magnetic stirrers 33 at each stationary position of the first mixing mechanism are started to quickly mix the urine sediment in each urine storage test tube 13. After mixing, it is convenient to subsequently absorb the urine sediment and send it to the microscope for detection.
[0080] The magnetic stirrers 33 at each stationary position here mainly have two functions: one is to be used as a stirrer; the other is to be used as a horizontal support.
[0081] In any of the above schemes, preferably, a stirring power supply 34 is fixedly installed at the bottom of the centrifugal main chamber 11 on both sides of the first mixing mechanism, and the stirring power supply 34 is used to supply power to the first mixing mechanism and the second mixing mechanism.
[0082] In any of the above schemes, it is preferred that the second mixing mechanism includes a number of horizontal centrifugal electric cylinders 35 that are evenly and spaced apart along the circumferential direction of the anti-corrosion drum 9, and the cylinder barrel of each of the horizontal centrifugal electric cylinders 35 is fixedly mounted on the upper outer wall of the anti-corrosion drum 9. The inner end of the piston rod of each of the horizontal centrifugal electric cylinders 35 moves through the through hole at the corresponding position and extends into the centrifugal main cavity 11 of the anti-corrosion drum 9. The inner end of the piston rod of each of the horizontal centrifugal electric cylinders 35 is fixed with a horizontal centrifugal magnetic stirrer 36, and each of the horizontal centrifugal magnetic stirrers 36 is coaxially arranged with the test tube storage tube 17 in a horizontal centrifugal state at the corresponding position.
[0083] The second mixing mechanism works to effectively mix the urine sediment pushed to the distal end of each urine storage tube 13 in a centrifugal state. In the mixing state, the horizontal centrifugal magnetic stirrer 36 can achieve the purpose of rapid mixing.
[0084] In any of the above schemes, preferably, the centrifugal drive assembly includes a centrifugal motor 37 fixedly mounted on the bottom of the lower chamber 8, a belt transmission member 38 is mounted on the output shaft of the centrifugal motor 37, and a vertical shaft support bearing seat 39 is movably mounted on the bottom of the central axis of the driven pulley 3801 of the belt transmission member 38, the bottom of the vertical shaft support bearing seat 39 is fixedly arranged, and the top of the central axis of the driven pulley 3801 of the belt transmission member 38 is movably extended to the interior of the upper chamber 7 and fixedly connected to the bottom center of the anti-corrosion drum 9;
[0085] When the centrifugal drive assembly is working, it relies on the centrifugal motor 37 and the belt transmission member 38 to realize the driving of the rotational power, thereby ensuring the centrifugal effect and efficiency during the centrifugal treatment.
[0086] A supporting steel ball 40 is movably engaged in each slot at the bottom of the anti-corrosion drum 9 , and the bottom of each supporting steel ball 40 is supported on the top of the middle partition 6 .
[0087] During the centrifugal rotation process, the operation of the supporting steel balls 40 can effectively achieve the purpose of support and guidance.
[0088] In any of the above solutions, preferably, a push armrest 41 is fixedly mounted on the upper outer side walls of the left and right sides of the chassis 1;
[0089] Universal wheel sets 42 with brakes are fixedly mounted at the four corners of the bottom of the chassis 1 .
[0090] The entire system can be easily moved and flexibly transferred by relying on the universal wheel set 42. At the same time, during the movement, each side push armrest 41 can be used to achieve effective pushing and convenient force generation.
[0091] In any of the above solutions, preferably, a lifting support assembly is fixedly installed on the bottom of the chassis 1 inside each of the universal wheel sets 42.
[0092] In any of the above schemes, it is preferred that the lifting support assembly includes a vertical internal screw tube 43 fixedly installed at the bottom of the chassis 1, an internal thread is provided in the inner cavity of the vertical internal screw tube 43, an external threaded support column 44 is screwed into the inner thread of the inner cavity of the vertical internal screw tube 43, an external thread is provided on the outer wall of the external threaded support column 44, and a support foot 19 is fixedly installed at the bottom of the external threaded support column 44, and the support foot 19 is supported on the ground in the working state and is higher than the ground in the idle state.
[0093] When the entire system needs to be stable, the height of the support foot 19 can be adjusted by operating each lifting support component. During adjustment, rotating the support foot 19 can drive the corresponding externally threaded support column 44 to rotate and lift, thereby controlling the externally threaded support column 44 to drive the support foot 19 at its bottom to move downward and support it on the ground.
[0094] Specific working principle:
[0095] The urine sample detection test centrifuge processing system for realizing urine sediment separation in the present invention adopts a structure that is easy to move as a whole, which can be flexibly moved when in use and stably positioned when needed; the entire system relies on the centrifugal drive assembly to realize the high-speed centrifugal operation of the overall urine sample centrifugal storage assembly, thereby effectively ensuring the high-speed rotation of the anti-corrosion drum 9 and its internal components. During the high-speed rotation process, it is necessary to control the set speed to achieve the operation of centrifugal separation of urine sediment at an appropriate speed for the multiple urine samples stored inside.
[0096] Specifically, when the entire system relies on the centrifugal drive assembly to realize the high-speed centrifugal operation of the entire urine sample centrifugal storage assembly, the entire driving process is as follows: the centrifugal motor 37 inside the centrifugal drive assembly is powered on, the centrifugal motor 37 is controlled to rotate, and the speed is gradually controlled to stabilize at 1500r / min, and the centrifugal treatment is performed for 5 minutes. When the centrifugal motor 37 rotates, the output end of its motor shaft drives the belt transmission member 38 connected thereto to operate, and the driven pulley 3801 at the output end of the belt transmission member 38 drives the anti-static pulley 3801 connected thereto to operate. The anti-corrosion drum 9 rotates, and when the anti-corrosion drum 9 rotates, it drives the upper cover turntable 10 fixed to its top to rotate, thereby driving the various components in the centrifugal main chamber 11 of the anti-corrosion drum 9 fixed relatively to the upper cover turntable 10 to follow the operation. Since the upper ends of the test tube storage tubes 17 inside the urine sample centrifugal storage assembly are in a horizontal axis fixed axis hinged state, and the bottoms of the test tube storage tubes 17 are in a vertical and free state in a normal state, when the entire urine sample centrifugal storage assembly rotates with a fixed axis, the test tube storage tubes 17 are in a vertical and free state. 17 and the central axis of the driven pulley 3801 have a certain rotation radius, so they will be subjected to the outward centrifugal force. This can be known from the common knowledge of physical mechanics. In addition, since the upper end of each test tube storage tube 17 is limited by the corresponding fixed rotation shaft 18, it can only rotate around the fixed axis and cannot shift horizontally. Therefore, the lower end of each test tube storage tube 17 in a free state will gradually change from a vertical state to a state where the lower part is gradually thrown upward and outward after being subjected to the outward centrifugal force. As the speed continues to increase, the centrifugal force As the force gradually increases, the upward tilt of the lower end of each test tube storage tube 17 gradually increases. When the rotation speed reaches 1500r / min, each test tube storage tube 17 will be in a horizontal or nearly horizontal state together with the urine storage test tube 13 inside it. When each urine storage test tube 13 cannot reach a horizontal state, the corresponding static position magnetic stirrer can also be driven upward by the static position vertical cylinders below it to support the corresponding test tube storage tube 17 to a horizontal state, and horizontal centrifugation can be performed in this state.
[0097] The centrifuge processing system uses a set speed when processing urine samples (during centrifugation, take 10mL-15mL of fresh urine sample liquid and place it in the urine storage test tube in advance, and put the urine storage test tube in place. After storage and installation, start the centrifuge and perform centrifugal treatment for 5 minutes. The speed is controlled at 1500r / min. After centrifugation is completed, the supernatant and urine sediment are distributed in different positions in the test tube). During centrifugation, it can effectively ensure that the urine sample is in a horizontal state for centrifugation, and can effectively ensure that the urine sediment with heavier weight and density is concentrated at the distal end of the urine storage test tube and the supernatant is concentrated at the proximal end of the urine storage test tube under the centrifugal state, thereby ensuring the boundary effect between the residue and the liquid, and ensuring the centrifugal precipitation effect of the urine sediment inside the urine sample.
[0098] From clinical and physical knowledge, we know that the density of the visible components of urine sediment is greater than the density of urine. Therefore, when in a horizontal centrifugal state, the urine sediment with a larger density will be subjected to a larger centrifugal force, and will therefore accumulate at the distal end of the urine storage tube, while the urine supernatant with a smaller density will be subjected to a smaller centrifugal force, and will therefore accumulate in the middle and proximal ends of the urine storage tube. In this way, the supernatant in the urine and the urine sediment can be effectively separated and distributed, the separation effect can be improved, and it can be ensured that as much urine sediment as possible can be precipitated and accumulated at the distal end, thereby ensuring the separation effect and facilitating the subsequent urine sediment detection and analysis under a microscope to obtain relatively accurate results.
[0099] During the centrifugal operation, the second mixing mechanism can be used to fully mix the urine samples at their respective positions. At the same time, after the centrifugal operation is completed, the first mixing mechanism can also be used to mix the urine samples at the corresponding positions, thereby effectively ensuring the processing effect of the urine samples. When the urine sample horizontal centrifuge mechanism is working, each urine sample storage unit can be used to store urine storage test tubes 13 containing urine samples. When each urine storage test tube 13 follows the anti-corrosion rotating drum 9 to rotate at high speed, it will gradually be transformed from a vertical state to a nearly horizontal state under the state of centrifugal force, until it is a horizontal state. Centrifugation in a horizontal state can better ensure that the urine sediment with higher density is precipitated to the far end of the test tube under the action of centrifugal force, thereby improving the separation effect, preventing the urine sediment from adhering to the middle side wall of the test tube, and ensuring the precipitation rate of the urine sediment; in the centrifugal state, if in order to improve the efficiency of the operation, the supernatant urine at the proximal end of the test tube can be separated by centrifugal force and sucked out under the action of the pump body by controlling the work of the urine separation unit, and the urine sediment mixture is retained at the far end of the test tube after suction, thereby ensuring the efficiency and effect of the residue-liquid separation, and the separated and sucked urine can be transported to the outside for collection via a pipeline.
[0100] When the urine separation unit is in an idle state, it is not in contact with the urine storage test tube 13 at the corresponding position. When it is necessary to control the urine separation unit to suck out the urine from the proximal end of each urine storage test tube 13, the corresponding electric liquid samplers can be controlled to move and seal and insert with the spring-loaded one-way valve 22 at the end of each urine storage test tube 13 to achieve the purpose of communication with the interior of the urine storage test tube 13; when each spring-loaded one-way valve 22 is matched with the corresponding electric liquid sampler, the pump body inside each routing rotor housing 12 is started to suck out the supernatant urine from the proximal end of the corresponding urine storage test tube 13 in a centrifugal state. After sucking out, only a small amount of urine and all the urine sediment are retained in each test tube, which is convenient for later observation and detection of the urine sediment under a microscope.
[0101] The separation effect of urine sediment determines the accuracy of subsequent urine sediment microscopy. Therefore, the centrifuge structure designed in the present invention can better achieve the centrifugal effect of urine sediment in urine sample liquid, and better separate and distribute the supernatant in urine and urine sediment in urine. Urine sediment separation is to centrifuge the visible components in urine.
[0102] The present invention performs synchronous centrifugal separation on multiple urine samples from the same patient to more objectively analyze the urine sediment separation effect. During the specific operation, the test subject takes morning urine. Before the urine sediment test, the urine sample must be lightly mixed, and then 10mL-15mL of fresh urine sample liquid is dripped into each urine storage test tube. After the urine sample is dripped, each urine storage test tube is sealed, and then each urine storage test tube containing the same volume of urine sample is placed in the interior of each vertical test tube storage tube corresponding to the centrifuge in the present invention, and then the transparent tempered glass cover turntable 10 is fixed to the top of the anti-corrosion drum 9 by multiple quick-release screws.
[0103] Two methods are set up for separating urine and urine sediment. The first is centrifugation and simultaneous separation and extraction of urine sediment: this method can be selected as needed to directly complete the separation of supernatant urine in the centrifugal state and aspirate it out so that only urine sediment and an appropriate amount of urine exist in the test tube, thereby improving the efficiency of urine sample centrifugation and urine sediment extraction; the second is centrifugation and resetting and standing after the centrifugation is completed, waiting for the supernatant to be stratified and then manually aspirating the supernatant to complete the collection of urine sediment. Choosing two methods according to needs can better ensure the centrifugal collection effect of urine sediment.
[0104] Specifically, centrifugation in a horizontal state can better ensure that the urine sediment with higher density is precipitated to the far end of the test tube under the action of centrifugal force, thereby improving the separation effect; since the traditional centrifugation method uses an angular centrifuge in an inclined state for centrifugation, centrifugal force is generated during the centrifugation process, and a component of force vertical to the inside of the test tube is also generated. Therefore, part of the urine sediment will adhere to the inner wall of the test tube in the lower middle section or the lower lower section under the combined action of separation and centrifugal force. The separation in this state may make the boundary between the urine supernatant and the urine sediment not obvious, and the angular centrifuge can only make the visible components of the urine sediment settle on the inclined surface at the bottom of the test tube. When the supernatant is poured out to obtain the visible components, the visible components will be lost. This existing technical problem actually exists in the existing technology and will not be repeated here.
[0105] In order to overcome the problem of urine sediment sticking to the wall when pouring the supernatant from the existing angular centrifuge, the present invention separates the supernatant under two states to achieve the goal of leaving all the visible components of the urine sediment inside the test tube.
[0106] When centrifuging in a horizontal state, the centrifugal speed can be maintained at a horizontal state after the centrifugation is completed, and there is no force component perpendicular to the inner wall of the test tube. Therefore, under the action of the horizontal centrifugal force, the urine sediment with a smaller content will be accumulated at the far bottom of the test tube under the action of the horizontal outward centrifugal force, and there will be no accumulation of urine sediment at the bottom of the middle section like in an angular centrifuge.
[0107] In the horizontal centrifugal state, the supernatant inside the test tube is sucked out by relying on the inner valve tube end, leaving the urine sediment, so that the internal urine sediment can be directly used for microscopic examination in the later stage.
[0108] After the horizontal centrifugation is completed, the entire centrifugal speed is controlled to slowly decrease, and each urine storage test tube is returned to the vertical state and reset and left to stand, waiting for the supernatant to be stratified. At this time, the present invention does not adopt the traditional pouring method, but manually sucks out the supernatant, leaving the urine sediment at the bottom of the test tube to achieve the purpose of collecting the urine sediment. Therefore, there is no problem of pouring the urine sediment, and there is no problem of urine sediment sticking to the wall. When the urine sediment needs to be completely separated, it can be rinsed with a medical sterile liquid that does not affect the test results to ensure that the urine sediment will not be lost or residual.
[0109] The above embodiments are only used to illustrate the technical solutions of the present invention, rather than to limit the same. Although the present invention has been described in detail with reference to the above embodiments, those skilled in the art should understand that the technical solutions described in the above embodiments can still be modified, or some or all of the technical features therein can be replaced by equivalents. However, these modifications or replacements do not deviate the essence of the corresponding technical solutions from the scope of the technical solutions of the embodiments of the present invention. For those skilled in the art, any replacement improvements or changes made to the implementation methods of the present invention fall within the scope of protection of the present invention.
[0110] Any matters not described in detail in the present invention are well-known technologies to those skilled in the art.
Claims
1. A urine sample testing centrifuge processing system for separating urine sediment, comprising a chassis, a front door panel fixed to the front of the chassis, a top cover fixed to the top of the chassis, a single door hingedly connected to the middle of the front door panel, and an electrical control box mounted on the single door, characterized in that: The chamber inside the chassis is divided into an upper chamber and a lower chamber by a middle partition. A centrifugal drive assembly is installed in the lower chamber, and a urine sample centrifugal storage assembly is installed in the upper chamber. The output end of the centrifugal drive assembly movably and sealably passes through the through hole of the middle partition and is coaxially fixedly connected to the urine sample centrifugal storage assembly. The urine sample centrifugal storage assembly includes an anti-corrosion drum, the bottom center of the anti-corrosion drum is fixedly connected to the output end of the centrifugal drive assembly, an upper cover turntable is fixed on the top of the anti-corrosion drum, and a urine sample horizontal centrifugal mechanism, a first mixing mechanism, and a second mixing mechanism are respectively installed in the centrifugal main cavity of the anti-corrosion drum; The urine sample horizontal centrifuge mechanism includes a routing rotor housing fixed to the center of the upper cover turntable, a urine separation unit fixed to the bottom of the routing rotor housing, and a urine sample storage unit installed on the side walls of the middle part of the urine separation unit. Each urine sample storage unit is used to place a urine storage tube, and each urine storage tube stores a urine sample. The urine separation unit is controlled to suck out the supernatant separated by centrifugal force and located at the proximal end of the urine storage tube. After the supernatant is sucked out, the urine sediment mixed liquid retained in the urine storage tube is located at the distal end of the urine storage tube. The urine separation unit includes a hollow horizontal rotor chamber fixed to the bottom of the wiring rotor housing, and electric liquid collectors are fixed along the four sides of the chamber body of the hollow horizontal rotor chamber to cooperate with the urine sample storage units at corresponding positions; The urine sample storage unit includes two positioning ears that are relatively spaced and fixed on the outer side wall of the hollow horizontal rotor bin, a test tube storage tube is provided between the two positioning ears, and both sides of the upper part of the test tube storage tube are movably inserted into the rotating holes of the positioning ears at corresponding positions through a fixed rotating shaft, a urine storage test tube is installed in the sample storage cavity of the test tube storage tube, the urine storage test tube includes a test tube body, a sealing cover is sealed at the mouth of the test tube body, and a spring-loaded one-way valve is fixed at the center of the outer end of the sealing cover; each of the test tube storage tubes is in a vertical state in an idle state and in a horizontal state in a centrifugal state; The electric liquid sampler includes a micro-electric cylinder fixed inside the hopper body of the hollow horizontal rotor hopper, and the electric liquid sampler includes a sealed outer tube sleeve fixed at the end of the piston rod of the micro-electric cylinder and with the inner end sealed, which is used to seal and sleeve with the outer side wall of the spring-type one-way valve at the corresponding position. A central pushing shaft is fixed at the center of the cavity of the sealed outer tube sleeve. When the micro-electric cylinder drives the sealed outer tube sleeve toward the spring-type one-way valve, the central pushing shaft can push open the valve ball inside the spring-type one-way valve and realize the conduction of the spring-type one-way valve.
2. A urine sample detection test centrifuge processing system for achieving urine sediment separation according to claim 1, characterized in that: Each of the electric liquid samplers is powered by a liquid sampling mobile power supply fixed inside the hollow horizontal rotor bin. The upper end of each of the electric liquid samplers is movable through the interior of the routing rotor casing and passes through the top center of the routing rotor casing to communicate and cooperate with the external liquid drawing tube group at the corresponding position.
3. A urine sample detection test centrifuge processing system for achieving urine sediment separation according to claim 2, characterized in that: The first mixing mechanism includes a plurality of static position vertical cylinders respectively fixedly installed at the bottom of the centrifugal main chamber below each vertical test tube storage tube, and a static position magnetic stirrer is fixedly installed on the top of the piston rod of the static position vertical cylinder. Each static position magnetic stirrer has two working positions when in operation; In the first working position, the static magnetic stirrer is located below the corresponding test tube storage tube in the vertical state and after being started, it fully stirs and mixes the urine sediment mixture remaining at the bottom of the urine sample inside the urine storage tube; In the second working position, the static magnetic stirrer serves as a lifting member and is in a shutdown state to support the test tube storage tube in a high-speed centrifugal state at a corresponding position and ensure that the test tube storage tube is in a horizontal state.
4. A urine sample detection test centrifuge processing system for achieving urine sediment separation according to claim 3, characterized in that: A stirring power supply is fixedly installed at the bottom of the centrifugal main cavity on both sides of the first mixing mechanism, and the stirring power supply is used to supply power to the first mixing mechanism and the second mixing mechanism.
5. A urine sample detection test centrifuge processing system for achieving urine sediment separation according to claim 4, characterized in that: The second mixing mechanism includes a plurality of horizontal centrifugal electric cylinders that are evenly and spaced apart along the circumferential direction of the anti-corrosion drum. The cylinder of each horizontal centrifugal electric cylinder is fixedly mounted on the upper outer wall of the anti-corrosion drum. The inner end of the piston rod of each horizontal centrifugal electric cylinder is movable through the through hole at the corresponding position and extends into the centrifugal main cavity of the anti-corrosion drum. A horizontal centrifugal magnetic stirrer is fixed at the inner end of the piston rod of each horizontal centrifugal electric cylinder. Each horizontal centrifugal magnetic stirrer is coaxially arranged with the test tube storage tube in the horizontal centrifugal state at the corresponding position.
6. A urine sample detection test centrifuge processing system for achieving urine sediment separation according to claim 5, characterized in that: The centrifugal drive assembly includes a centrifugal motor fixedly mounted on the bottom of the lower chamber, a belt transmission member is mounted on the output shaft of the centrifugal motor, a vertical shaft support bearing seat is movably mounted on the bottom of the central axis of the driven pulley of the belt transmission member, and the top of the central axis of the driven pulley of the belt transmission member is movably extended into the interior of the upper chamber and fixedly connected to the bottom center of the anti-corrosion drum.
Citation Information
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