Active foliar fertilizer with insecticidal effect

Abstract

The present invention relates to the technical field of pesticides, and in particular to an active foliar fertilizer with insecticidal efficacy. An insecticidal composition, characterized in that its active ingredient is a binary compound of cyclohexaprid and farnesol. The insecticidal mechanisms of farnesol and other active ingredients in the insecticidal composition of the present invention are different. When used in combination, they can effectively delay the development of insecticide resistance and extend the service life of the insecticidal composition. Secondly, the pest control effect can be improved, the amount of active ingredients used can be reduced, and the cost of pest control can be reduced. In addition, the active foliar fertilizer of the present invention contains both insecticidal ingredients and water-soluble fertilizer ingredients. When used, it can not only prevent and control crop pests, but also provide nutrients for crops. The two cooperate with each other to improve the yield and quality of crops.

Description

Technical Field

[0001] The invention relates to the technical field of pesticides, and in particular to an active foliar fertilizer with insecticide efficacy. Background Art

[0002] Farnesol, English name Farnesol, CAS number: 4602-84-0, molecular formula: C 15 H 26 O, the structural formula is as follows:

[0003]

[0004] Farnesol is the main component of the essential oil of the spice plant Cinamomum tenuipilum Kosterm. It has complex biological activities against a variety of arthropods and, as a component of insect juvenile hormone, can affect insect development. "Combined toxicity of farnesol and nicotine against apple yellow aphids" (Li Zhenxi et al., Chinese Journal of Biological Control, February 2019, 35(1)37-43) was used to test the combined aphidicide activity of farnesol and nicotine, finding that the combination of farnesol and nicotine had a significant synergistic effect in killing aphids.

[0005] Aphids, also known as sticky insects or honey beetles, belong to the order Hemiptera, class Insecta, phylum Arthropoda. Nearly 5,000 species are known worldwide, with over 1,000 species discovered in my country. Aphids pose a serious threat to plants. They directly harm plants by sucking sap or releasing toxic substances, affecting their normal physiological metabolism and growth. Furthermore, aphids are vectors of plant pathogens, spreading the majority of common viral diseases, further increasing their impact on plants.

[0006] Chemical pesticides still dominate aphid control, but long-term application of a single chemical can easily lead to pest resistance, while also causing a range of problems, including pesticide residues and environmental pollution. Several aphid species, such as the wheat aphid, have developed varying degrees of resistance to a variety of existing chemical pesticides.

[0007] Combining pesticide active ingredients with different mechanisms of action is an effective and efficient way to develop new pesticides and control resistant pests and diseases. Compounding different pesticide active ingredients can exhibit three types of effects: additive, synergistic, and antagonistic. Through extensive laboratory experiments, the inventors discovered that combining abamectin, butene-fipronil, cyclohexaprid, or pymetrozine with farnesol exhibits a synergistic effect against aphids. This could provide support for integrated aphid control and the development of new chemical agents for aphid control.

[0008] There are no relevant reports on related compounding at present. Summary of the Invention

[0009] The purpose of the present invention is to provide an active foliar fertilizer with insecticidal efficacy to solve the problems existing when using a single chemical agent.

[0010] To achieve the above object, the present invention provides the following technical solutions:

[0011] The first object of the present invention is to provide an insecticidal composition, the active ingredients of which are a binary compound of abamectin, butene fipronil, cyclohexaprid or pymetrozine and farnesol.

[0012] Preferably, the mass ratio of avermectin to farnesol is 1-9:10-1.

[0013] Preferably, the mass ratio of the butene fipronil to farnesol is 1-25:5-1.

[0014] Preferably, the mass ratio of cyclohexaprid to farnesol is 1-7:30-1.

[0015] Preferably, the mass ratio of pymetrozine to farnesol is 1-15:3-1.

[0016] The second object of the present invention is to provide an insecticide, which is composed of the insecticide composition containing farnesol and auxiliary ingredients allowed to be added in pesticide science.

[0017] Preferably, the mass of the farnesol-containing insecticide composition accounts for 0.75-80% of the total mass of the insecticide.

[0018] Preferably, the pesticide is in the form of a wettable powder, a water dispersible granule or a suspension concentrate.

[0019] The third object of the present invention is to provide a foliar fertilizer, which is composed of the insecticide and a water-soluble fertilizer, wherein the water-soluble fertilizer is selected from one or more of potassium sulfate, ammonium chloride, potassium nitrate, zinc sulfate and sodium octaborate tetrahydrate.

[0020] Compared with the prior art, the present invention has the following beneficial effects:

[0021] (1) The avermectin in the insecticide composition of the present invention interferes with neurophysiological activities and stimulates the release of γ-aminobutyric acid, which has an inhibitory effect on nerve conduction in arthropods;

[0022] The mechanism of action of butene fipronil is to hinder the chloride metabolism controlled by insect γ-aminobutyric acid, and it has high insecticidal activity against pests such as aphids, leafhoppers and planthoppers;

[0023] Cyclohexaprid selectively inhibits the nicotinic acetylcholinesterase receptors of the insect nervous system and is a highly effective neonicotinoid insecticide.

[0024] Pymetrozine can specifically block the feeding behavior of insects, causing the insects to stop feeding immediately. Although they can still move, they will eventually die of starvation due to the irreversible feeding effect.

[0025] Farnesol, as one of the components of insect juvenile hormone, can affect insect development.

[0026] As can be seen from the above, farnesol and other active ingredients in the insecticidal composition of the present invention have different insecticidal mechanisms. When used in combination, they can effectively delay the development of insecticide resistance in pests and extend the service life of the insecticidal composition.

[0027] (2) When the active ingredients in the insecticide composition of the present invention are compounded, they exhibit a synergistic effect, which can improve the pest control effect, reduce the amount of active ingredients used, and reduce the cost of pest control.

[0028] (3) The active foliar fertilizer of the present invention contains both insecticide components and water-soluble fertilizer components. When used, it can not only prevent and control crop pests, but also provide nutrients for crops. The two work together to improve the yield and quality of crops. DETAILED DESCRIPTION

[0029] The present invention can be better understood according to the following examples. The contents described in the examples are only used to illustrate the present invention, and should not and will not limit the present invention described in detail in the claims.

[0030] Example :Indoor biological activity test of farnesol compound

[0031] 1. Test subjects: Aphids were collected from wheat fields in the suburbs of Zhengzhou. After 6 generations of rearing in the laboratory, healthy, wingless adult aphids with uniform body shape were selected as test subjects.

[0032] 2. Test agents

[0033] 92% Abamectin technical (Jiangsu Fengyuan Bioengineering Co., Ltd.)

[0034] 96% Butene-fipronil technical (Dalian Jiuxin Crop Science Co., Ltd.)

[0035] 95% cyclohexaprid technical (Sichuan Hebang Biotechnology Co., Ltd.)

[0036] 98% pymetrozine technical (Shandong United Pesticide Industry Co., Ltd.)

[0037] 95% farnesol technical (Shanghai Aladdin Biochemical Technology Co., Ltd.)

[0038] The original drug was first dissolved in dimethyl sulfoxide to prepare a single-dose stock solution, and then diluted with a 0.1% Tween-80 aqueous solution. Multiple groups of proportions were set up, and each single dose and each group of mixed proportions were set to 7 gradient mass concentrations according to the equal proportion method for standby use.

[0039] 3. Test method: (Refer to "NY / T 1154.6-2006 Pesticide Indoor Bioassay Test Guidelines Insecticides Part 6: Insecticide Activity Test - Insect Immersion Method")

[0040] Test insects were immersed in the solution for 10 seconds. Excess solution was removed with filter paper and the insects were then transferred to normal rearing conditions. Each treatment was repeated four times, with 20 insects immersed in each repetition. A treatment containing only 0.1% Tween-80 served as a blank control. Mortality was observed 24 hours after treatment, and the total number of insects and the number of dead insects were recorded for each treatment. This was used to calculate the corrected mortality rate for each treatment.

[0041]

[0042] In the above formula: P is the mortality rate, in %; K is the number of dead insects; N is the total number of insects treated.

[0043]

[0044] In the above formula: P1--corrected mortality rate, unit is %; P t --Treatment mortality, unit is %; P0--blank control mortality, unit is %.

[0045] 4. Data analysis: DPS software was used to perform regression analysis on the logarithmic concentration of each treatment agent and the corrected mortality probability value of each treatment, and the LC value of each treatment agent was calculated. 50 , and calculated the co-toxicity coefficient (CTC value) of the mixture according to Sun Yunpei's method.

[0046]

[0047] In the above formula: ATI - the toxicity index of the mixture; S - the LC of the standard agent 50 , the unit is mg / L; M--LC of the mixture 50 , unit is mg / L.

[0048] TTI=TI A ×P A +TI B ×P B

[0049] In the above formula: TTI - theoretical toxicity index of mixture; TI A --Toxicity index of agent A; P A--The percentage of agent A in the mixture, expressed as percentage (%); TI B --Toxicity index of agent B; P B --The percentage of agent B in the mixture, in percentage (%).

[0050]

[0051] In the above formula: CTC - co-toxicity coefficient; ATI - measured toxicity index of mixture; TTI - theoretical toxicity index of mixture.

[0052] 5. Efficacy evaluation

[0053] The synergistic effect of the agents was evaluated based on the calculated co-toxicity coefficient (CTC). CTC ≤ 80 indicated an antagonistic effect, 80 < CTC < 120 indicated an additive effect, and CTC ≥ 120 indicated a synergistic effect. The results are shown in Tables 1-4.

[0054] Table 1 Results of toxicity test of avermectin and farnesol complex against aphids

[0055]

[0056]

[0057] As can be seen from Table 1, within the mass ratio of 1-9:10-1, the co-toxicity coefficient of abamectin and farnesol against aphids was greater than 120, showing a synergistic effect.

[0058] Table 2 The results of toxicity test of the combination of butene-fipronil and farnesol to aphids

[0059]

[0060] As can be seen from Table 2, within the mass ratio of 1-25:5-1, the co-toxicity coefficient of butene-fipronil and farnesol to aphids was greater than 120, showing a synergistic effect.

[0061] Table 3 The results of toxicity test of cyclohexaprid and farnesol complex to aphids

[0062]

[0063] As can be seen from Table 3, within the mass ratio range of 1-7:30-1, the co-toxicity coefficient of cyclohexaprid and farnesol to aphids was greater than 120, showing a synergistic effect.

[0064] Table 4 Toxicity test results of pymetrozine and farnesol complex to aphids

[0065]

[0066] As can be seen from Table 4, within the mass ratio range of 1-15:3-1, the co-toxicity coefficient of pymetrozine and farnesol to aphids was greater than 120, showing a synergistic effect.

[0067] The above is only a preferred embodiment of the present invention. Those skilled in the art can make appropriate improvements without departing from the principles of the present invention. These improvements are also within the scope of protection of the present invention.

Claims

1. An insecticidal composition, characterized in that The active ingredient is prepared by binary compounding of cyclohexaprid and farnesol, wherein the mass ratio of the cyclohexaprid to farnesol is 1-7:30-1.

2. An insecticide, characterized in that The insecticide is composed of the insecticide composition according to claim 1 and auxiliary ingredients allowed to be added in pesticide science.

3. The insecticide according to claim 2, characterized in that The mass of the insecticide composition accounts for 0.75-80% of the total mass of the insecticide.

4. The insecticide according to claim 2, characterized in that The formulation of the insecticide is wettable powder, water dispersible granules or suspension.

5. A foliar fertilizer, characterized in that: The method comprises the insecticide according to claim 4 and a water-soluble fertilizer, wherein the water-soluble fertilizer is selected from one or more of potassium sulfate, ammonium chloride, potassium nitrate, zinc sulfate and sodium octaborate tetrahydrate.

Images