A catalytic reaction apparatus for processing fluoropyridinamide derivatives

Abstract

The application relates to the technical field of chemical production equipment, and particularly discloses a catalytic reaction device for processing fluoropyridine amide derivatives, which comprises a shell for placing reaction materials, a reaction cavity arranged in the shell, and a plurality of flow-limiting mechanisms for limiting the one-way passing of catalysts with a certain particle size, and a circulation cavity is formed between the shell and the reaction cavity; a stirring assembly is arranged in the reaction cavity. The reaction cavity and the circulation cavity in communication with the reaction cavity are arranged, in the reaction process, the plurality of flow-limiting mechanisms limit the one-way passing of catalysts with a certain particle size, and the reaction materials in the circulation cavity are recycled and delivered into the reaction cavity for reaction, the problem that the particle size of catalytic materials cannot be effectively controlled when the existing catalytic reaction device is used for processing fluoropyridine amide derivatives is solved, and the catalytic reaction device has a wide market prospect.

Description

TECHNICAL FIELD

[0001] The application belongs to the technical field of chemical production equipment, and specifically relates to a catalytic reaction device for processing fluoropyridine amide derivatives. BACKGROUND

[0002] With the development of modernization of agriculture, herbicides are also widely used in agricultural production to improve production efficiency. As a product that can be used to eliminate or inhibit the growth of plants, herbicides can be widely used to control weeds and other harmful plants in farmland, orchard, river, etc. and have wide application value in actual agricultural production. Among them, herbicides are generally divided into organic compounds or inorganic compounds. Generally, organic compound herbicides are mainly synthesized from organic compounds such as benzene, alcohol, fatty acid and organic amine, such as ethers, substituted ureas, phenoxyacetic acids, pyridines, amides, organophosphorus compounds, etc.

[0003] At present, amides and their derivatives, especially fluorine-containing pyrazole amide derivatives, generally have significant antifungal activity, which can provide a basis for the development of new fungicides with fluorine-containing pyrazole amide derivatives as active ingredients. Generally, herbicides containing pyridine amide structure can inhibit the synthesis of carotenoid biosynthesis in herbaceous plants, and are a broad-spectrum selective herbicide, mainly suitable for preventing and controlling grass weeds and broadleaf weeds in barley and corn fields, etc. The preparation of new fluoropyridine amide compounds and their application in herbicides have become a research hotspot. For example, the existing Chinese patent with the publication number CN113666868A discloses a synthesis method of fluoropyridine amide derivatives, which uses trifluoromethyltrimethylsilane as a trifluoromethylating reagent, performs trifluoromethylation on the aromatic ring of pyridine carboxylic acid compound in a synergistic catalytic system of potassium fluoride and silver trifluoromethanesulfonate, generates m-trifluoromethyl pyridine carboxylic acid compound, and then continues to react in a catalytic system of N-hydroxy succinimide and dicyclohexyl carbodiimide to generate a derivative containing fluoropyridine amide structure. One of the key steps of the method is to add pyridine carboxylic acid compound and trifluoromethyltrimethylsilane as a trifluoromethylating reagent into 1,2-dichloroethane, stir and dissolve, then add catalyst potassium fluoride and co-catalyst silver trifluoromethanesulfonate, perform warming reaction, perform vacuum distillation, separation and purification, and obtain m-trifluoromethyl pyridine carboxylic acid compound.

[0004] However, the prior art in the above has the following defects: in the processing of fluoropyridine amide derivatives, a synergistic catalytic system of potassium fluoride and silver trifluoromethanesulfonate is used, and the existing catalytic reaction device for processing fluoropyridine amide derivatives cannot effectively control the particle size of the catalytic material, which affects the stable progress of the reaction as the particle size of the catalytic material becomes smaller and smaller during the continuous reaction. SUMMARY

[0005] The embodiment of the present application aims to provide a catalytic reaction device for processing fluoropyridine amide derivatives, so as to solve the problem that the existing catalytic reaction device cannot effectively control the particle size of the catalytic material when used for processing fluoropyridine amide derivatives.

[0006] The embodiment of the present application is implemented as follows: a catalytic reaction device for processing fluoropyridine amide derivatives comprises a shell for placing reaction materials, and further comprises:

[0007] a reaction cavity arranged inside the shell and used for accommodating the reaction materials and adding a catalyst for catalytic reaction, wherein the shell and the reaction cavity form a circulation cavity;

[0008] a stirring assembly arranged in the reaction cavity and used for stirring the reaction materials in the reaction cavity; and

[0009] a plurality of flow limiting mechanisms uniformly arranged on the side of the shell of the reaction cavity facing the circulation cavity and used for limiting the one-way passage of the catalyst with a certain particle size.

[0010] Preferably, the flow limiting mechanism comprises a pipe body and a discharge cavity arranged in the pipe body, and a movable piece is arranged at the end of the pipe body away from the shell of the reaction cavity; the flow limiting mechanism further comprises a screening mechanism, and the pipe body is in communication with the reaction cavity through the screening mechanism.

[0011] Preferably, the screening mechanism comprises a connecting pipe for communicating with the pipe body, and a blocking piece is arranged in the connecting pipe, and a plurality of screen holes are formed between the blocking piece and the inner wall of the connecting pipe.

[0012] The present application has the following beneficial effects:

[0013] Compared with the prior art, the catalytic reaction device for processing fluoropyridine amide derivatives provided by the embodiment of the present application comprises a shell for placing reaction materials, a reaction cavity arranged inside the shell, and a plurality of flow limiting mechanisms for limiting the one-way passage of the catalyst with a certain particle size, wherein the shell and the reaction cavity form a circulation cavity; and a stirring assembly is arranged in the reaction cavity. The device is provided with the reaction cavity and the circulation cavity in communication with the reaction cavity, and in the reaction process, the plurality of flow limiting mechanisms limit the one-way passage of the catalyst with a certain particle size, and the reaction materials in the circulation cavity are recirculated and delivered into the reaction cavity for reaction, thereby solving the problem that the existing catalytic reaction device cannot effectively control the particle size of the catalytic material when used for processing fluoropyridine amide derivatives, and improving the practicability of the device. BRIEF DESCRIPTION OF DRAWINGS

[0014] In order to make the technical solutions in the embodiments of the present application clearer, the accompanying drawings needed in the embodiments or prior art description will be briefly introduced. Obviously, the accompanying drawings in the following description only show some embodiments of the present application.

[0015] Figure 1 A perspective view of a catalytic reaction device for processing fluoropyridine amide derivatives according to an embodiment of the present application.

[0016] Figure 2 A structural schematic view of a catalytic reaction device for processing fluoropyridine amide derivatives according to an embodiment of the present application.

[0017] Figure 3 A structural schematic view of a flow limiting mechanism in a catalytic reaction device for processing fluoropyridine amide derivatives according to an embodiment of the present application.

[0018] Figure 4 A structural schematic view of a screening mechanism in a catalytic reaction device for processing fluoropyridine amide derivatives according to an embodiment of the present application.

[0019] Figure 5 An internal structural schematic view of a catalytic reaction device for processing fluoropyridine amide derivatives according to another embodiment of the present application.

[0020] Figure 6 A structural schematic view of a stirring assembly in a catalytic reaction device for processing fluoropyridine amide derivatives according to another embodiment of the present application.

[0021] Figure 7 A connection relationship between a sealing rotating shaft and a transmission in a catalytic reaction device for processing fluoropyridine amide derivatives according to another embodiment of the present application.

[0022] Figure 8 A structural schematic view of a slag cleaning mechanism in a catalytic reaction device for processing fluoropyridine amide derivatives according to another embodiment of the present application.

[0023] Figure 9 A structural schematic view of a cleaning brush in a catalytic reaction device for processing fluoropyridine amide derivatives according to another embodiment of the present application.

[0024] In the figure: 1 - shell; 2 - connecting cover; 3 - communication port; 4 - feeding port; 5 - first circulating pipeline; 6 - second circulating pipeline; 7 - pump body; 8 - base; 9 - discharging port; 10 - circulating cavity; 11 - reaction cavity; 12 - flow limiting mechanism; 13 - pipe body; 14 - discharging cavity; 15 - movable piece; 16 - screening mechanism; 17 - connecting pipe; 18 - screen hole; 19 - blocking piece; 20 - driving mechanism; 21 - sealing rotating shaft; 22 - stirring piece; 23 - sealing limiting piece; 24 - locking piece; 25 - speed changer; 26 - driving motor; 27 - slag removing mechanism; 28 - fixing piece; 29 - built-in driver; 30 - telescopic shaft; 31 - cleaning brush; 32 - brush body; 33 - connecting clamping groove. DETAILED DESCRIPTION

[0025] In order to make the technical problems, technical solutions and beneficial effects of the present application clearer, the technical solutions in the embodiments of the present application will be described clearly and completely below in conjunction with the accompanying drawings of the embodiments of the present application. Obviously, the described embodiments are only part of the embodiments of the present application, rather than all the embodiments. Based on the embodiments in the present application, all other embodiments obtained by those of ordinary skill in the art without creative effort belong to the scope of protection of the present application.

[0026] In the description of the present application, it should be understood that, unless explicitly specified and limited, "on" or "under" of a first feature to a second feature can include that the first and second features are in direct contact, or that the first and second features are not in direct contact but are in contact through another feature between them. Moreover, "on", "above" and "over" of the first feature to the second feature includes that the first feature is directly above and obliquely above the second feature, or only indicates that the horizontal height of the first feature is higher than that of the second feature. "Below", "under" and "underneath" of the first feature to the second feature includes that the first feature is directly below and obliquely below the second feature, or only indicates that the horizontal height of the first feature is less than that of the second feature. The above indicated orientation or positional relationship is based on the orientation or positional relationship shown in the drawings, which is only for the convenience of describing the present application and simplifying the description, and therefore cannot be understood as a limitation on the present application. In addition, the terms "first", "second" and the like are only for descriptive purposes, and cannot be understood as indicating or implying relative importance or implicitly indicating the number of the indicated technical features. Therefore, the features limited by "first", "second" and the like can explicitly or implicitly include one or more of the features. In the description of the present application, unless otherwise stated, the meaning of "a plurality of" is two or more.

[0027] The specific implementation of the present application will be described in detail below in conjunction with specific embodiments.

[0028] As Figures 1-4As shown, a structural diagram of a catalytic reaction device for processing fluoropyridine amide derivatives is provided, and the catalytic reaction device for processing fluoropyridine amide derivatives comprises a shell 1 for placing reaction materials, and additionally, the catalytic reaction device for processing fluoropyridine amide derivatives further comprises:

[0029] A reaction cavity 11 is arranged inside the shell 1 and is used to accommodate reaction materials and add catalysts for catalytic reaction, and the shell 1 and the reaction cavity 11 form a circulation cavity 10 therebetween;

[0030] A stirring assembly is arranged in the reaction cavity 11 and is used to stir the reaction materials in the reaction cavity 11, so as to promote the mixing uniformity of the reaction materials, ensure sufficient contact between the reaction materials and between the reaction materials and the catalysts during the reaction process, and improve the catalytic reaction efficiency; and

[0031] A plurality of flow limiting mechanisms 12 are uniformly arranged on the side of the shell of the reaction cavity 11 facing the circulation cavity 10, and are used to limit the one-way passage of catalysts with a certain particle size, so as to solve the problem that the existing catalytic reaction device cannot effectively control the particle size of the catalytic materials when used for processing fluoropyridine amide derivatives.

[0032] It should be noted that the existing Chinese patent with publication number CN113666868A discloses a synthesis method of fluoropyridine amide derivatives, which adopts a synergistic catalytic system of potassium fluoride and silver trifluoromethanesulfonate. One of the key steps of the method is to add pyridine carboxylic acid compound and trifluoromethyl trimethyl silane as a trifluoromethylating reagent into 1,2-dichloroethane, stir and dissolve, and then add catalyst potassium fluoride and co-catalyst silver trifluoromethanesulfonate, and after warming and reaction, reduce pressure distillation, separation and purification, to obtain m-trifluoromethyl pyridine carboxylic acid compound. However, in the processing of fluoropyridine amide derivatives, potassium fluoride is a crystalline powder, and silver trifluoromethanesulfonate is also known as silver trifluoromethyl sulfonate or silver trifluoromethane sulfonate, which has strong thermodynamic and chemical stability. When used as a catalytic system, the particle size of the two has certain requirements, and cannot be too large or too small. The existing catalytic reaction device for processing fluoropyridine amide derivatives has the problem of being unable to effectively control the particle size of the catalytic materials, so that the particle size of the catalytic materials will become smaller and smaller during the continuous reaction, thereby affecting the reaction efficiency, and also increasing the difficulty of subsequent filtration treatment.

[0033] In the embodiment of the present application, by setting the reaction cavity 11 and the circulation cavity 10 which can communicate with the reaction cavity 11, the reactant and the catalyst are placed in the reaction cavity 11 to perform the catalytic reaction in the reaction process, and the plurality of flow limiting mechanisms 12 limit the one-way passing of the catalyst with a certain particle size, that is, after the catalyst particle size is broken into smaller particle size by the stirring assembly, the smaller particle size catalyst can be filtered into the circulation cavity 10 through the flow limiting mechanism 12, and then the catalyst residue is filtered out through the external pipeline, and the reaction material in the circulation cavity 10 is recycled and delivered to the reaction cavity 11 to perform the reaction, thereby solving the problem that the existing catalytic reaction device cannot effectively control the particle size of the catalyst when used for processing fluoropyridine amide derivatives.

[0034] In an example of the present application, the flow limiting mechanism 12 is used to limit the one-way passing of the catalyst with a certain particle size, and the particle size requirement of the catalyst can be determined according to the actual catalytic reaction needs, which is not limited here, and is usually slightly smaller than the catalyst particle size corresponding to the optimal catalytic efficiency, that is, the catalyst with a particle size slightly smaller than the catalyst particle size corresponding to the optimal catalytic efficiency is limited to pass, and the catalyst with a particle size corresponding to the optimal catalytic efficiency cannot pass.

[0035] Further, as a preferred embodiment of the present application, the flow limiting mechanism 12 is arranged on the upper side of the shell of the reaction cavity 11, and the catalyst can be filtered one-way from the reaction cavity 11 into the circulation cavity 10.

[0036] In the embodiment of the present application, specifically, by arranging the flow limiting mechanism 12 on the upper side of the shell of the reaction cavity 11, in actual application, the flow limiting mechanism 12 can limit the one-way passing of the catalyst with a certain particle size from the reaction cavity 11 to the circulation cavity 10, that is, under the stirring of the stirring assembly, a rotating material flow path is formed, thereby generating a certain impact force to the flow limiting mechanism 12 and opening the opening of the flow limiting mechanism 12, after the catalyst is broken into smaller particle size by the stirring of the stirring assembly, the smaller particle size catalyst can pass through the opening of the flow limiting mechanism 12 and flow into the circulation cavity 10, thereby realizing the control of the catalyst particle size, and at the same time, the stirring process of the stirring assembly can be intermittent stirring, so that after the stirring is stopped, the impact force disappears, and the larger particle size catalyst particles which do not pass through the opening of the flow limiting mechanism 12 will fall back to the bottom of the reaction cavity 11 to participate in the catalytic reaction.

[0037] In addition, it should be noted that if there is a blockage, the outer wall of the shell 1 can be knocked to generate a downward impact force, so that the larger particle size catalyst particles fall back to the bottom of the reaction cavity 11 to participate in the catalytic reaction, and in addition, according to the production needs, after the reaction is completed, the upper side of the inner wall of the reaction cavity 11 can be cleaned by the cleaning brush to remove the blocked catalyst particles.

[0038] In one example of the present application, of course, in actual application, stirring will also be generated due to reworking of the stirring assembly, collisions between catalyst particles will occur so as to break the clogged larger particle catalyst into smaller particles, and after reaching a certain particle size, the catalyst particles will continue to pass through the flow limiting mechanism 12, which is a repeated cycle, so that the problem of catalyst particle clogging generally does not occur.

[0039] Further, as a preferred embodiment of the present application, the flow limiting mechanism 12 comprises a pipe body 13 and an exhaust cavity 14 arranged in the pipe body 13, and the pipe body 13 is rotatably arranged with a movable element 15 at one end away from the shell of the reaction cavity 11.

[0040] In the embodiment of the present application, specifically, the movable element 15 can be hingedly arranged at one end of the opening of the pipe body 13, and since it is arranged on the upper side of the shell of the reaction cavity 11 and the catalyst can be filtered from the reaction cavity 11 to the circulation cavity 10 in one direction, the movable element 15 can be in a closed state due to gravity in a non-stirring state, and will be opened due to impact force when stirring, so that catalysts of a certain particle size can pass through.

[0041] Of course, a spring can also be connected between the lower end of the movable element 15 and the inner wall of the pipe body 13 as needed, so as to achieve a closing effect, and only when the impact force is greater than the elastic force under the action of the impact force, the opening effect can be achieved. In addition, a one-way valve product in the prior art can also be used as needed, which will not be described here.

[0042] Further, as a preferred embodiment of the present application, the flow limiting mechanism 12 further comprises a screening mechanism 16 for limiting catalysts of a certain particle size to pass in one direction, and the pipe body 13 is in communication with the reaction cavity 11 through the screening mechanism 16.

[0043] In the embodiment of the present application, the pipe body 13 is in communication with the reaction cavity 11 through the screening mechanism 16, and the screening mechanism 16 of the flow limiting mechanism 12 is used to limit the catalysts of a certain particle size to pass in one direction, thereby solving the problem that the existing catalytic reaction device cannot effectively control the particle size of the catalytic material when used for processing fluoropyridine amide derivatives.

[0044] Further, as a preferred embodiment of the present application, the screening mechanism 16 comprises a connecting pipe 17 for communication with the pipe body 13, and a blocking piece 19 is arranged in the connecting pipe 17, and a plurality of screen holes 18 are formed between the blocking piece 19 and the inner wall of the connecting pipe 17.

[0045] In the embodiment of the present application, specifically, the blocking piece 19 can be similar to a sieve plate, and the screen holes 18 can be arranged in the sieve plate. Figure 4The cross-shaped structure shown, of course, can also be required to be provided with other number of sieve holes 18, here the cross-shaped structure is taken as an example to illustrate that four sieve holes 18 are formed between the barrier 19 and the inner wall of the connecting pipe 17, the size of the sieve hole 18 is slightly smaller than the suitable particle size of the catalyst required for catalytic reaction, thus it can ensure that the catalyst of this particle size remains in the reaction cavity 11 for catalysis, at the same time, since the cross-shaped structure is provided, the catalyst of larger particle size will hit on the cross-shaped structure and is not easy to block at the sieve hole 18.

[0046] Further, as a preferred embodiment of the present application, the connecting pipe 17 and the reaction cavity 11 are detachably connected, which can be connected in a threaded connection manner, so that the flow limiting mechanism 12 with a suitable screening particle size can be conveniently replaced according to the reaction needs.

[0047] Further, as a preferred embodiment of the present application, the shell 1 is provided with a connecting cover 2 at one end opening, the middle part of the connecting cover 2 is provided with a communication port 3 for mounting the stirring assembly, and the output end of the stirring assembly passes through the communication port 3 and extends into the reaction cavity 11.

[0048] In the embodiment of the present application, specifically, the connecting cover 2 can play a sealing effect, which can ensure the stirring of the stirring assembly while ensuring the sealing, of course, an insulation layer can also be provided between the connecting cover 2 and the shell 1 according to needs, the insulation layer is provided with an opening in the middle part for the output end of the stirring assembly to pass through, and the insulation layer can cover the communication between the right end of the circulating cavity 10 and the reaction cavity 11, so that the entire circulating path is only from top to right and then to bottom, in the shape of C, and finally the catalyst of small particle size is precipitated at the bottom and is discharged through the pipeline.

[0049] In an example of the present application, the connecting cover 2 and the shell 1 can be connected and fixed by using a positioning piece, which can be a nut, a buckle, a screw rod, etc., and in the present example, preferably, the positioning piece is a combination of a nut and a bolt.

[0050] Further, as a preferred embodiment of the present application, the catalytic reaction device for processing fluopyramamide derivatives further comprises a feeding port 4, the feeding port 4 is communicated with the reaction cavity 11, and is used for putting in reactants and catalysts.

[0051] As shown in the figure, Figures 2-4 As a preferred embodiment of the present application, the catalytic reaction device for processing fluopyramamide derivatives further comprises a first circulating pipeline 5 and a second circulating pipeline 6, the first circulating pipeline 5 is communicated with the circulating cavity 10, the second circulating pipeline 6 is communicated with the reaction cavity 11, and the shell 1 is provided with a pump body 7 outside for being communicated with the first circulating pipeline 5 and the second circulating pipeline 6, respectively.

[0052] In the embodiment of the present application, by setting the first circulating pipeline 5 and the second circulating pipeline 6, the small-particle-size catalysts screened by the flow-limiting mechanism 12 are precipitated in the stirring gap, at this time, by the working of the pump body 7, the reactants and solvents in the circulating cavity 10 are recycled and delivered to the reaction cavity 11, thereby improving the reaction efficiency of the materials, and in addition, the cleaning of the inside of the circulating cavity 10 can be realized when not in use.

[0053] As shown in Figures 1-9 Further, as a preferred embodiment of the present application, the stirring assembly comprises a driving mechanism 20, the output end of the driving mechanism 20 is provided with a sealed rotating shaft 21, one end of the sealed rotating shaft 21 extends into the reaction cavity 11, and the part of the sealed rotating shaft 21 located in the reaction cavity 11 is provided with a plurality of stirring pieces 22.

[0054] In the embodiment of the present application, the stirring assembly with the sealing structure can realize the stirring and mixing of the materials in the reaction cavity 11, thereby improving the catalytic reaction efficiency.

[0055] In an example of the present application, the structure of the stirring piece 22 will have a certain influence on the stirring effect, and the embodiment of the present application does not limit the specific structure of the stirring piece 22, for example, the stirring piece 22 can be U-shaped, rectangular, triangular, L-shaped or even flat, and can be adjusted according to the installation environment, here, for the convenience of description, the flat stirring piece 22 is taken as an example for description, but it is not limited thereto.

[0056] Further, as a preferred embodiment of the present application, the driving mechanism 20 comprises a driving motor 26, the output end of the driving motor 26 is connected with a speed changer 25, one end of the speed changer 25 is connected with the sealed rotating shaft 21 through a sealing limiting piece 23.

[0057] In the embodiment of the present application, the driving motor 26 can be a motor product in the prior art, for example, it can be a direct-current motor, an asynchronous motor or a synchronous motor, and the specific selection is made according to the actual demand, which is not limited here, as long as it can drive the sealed rotating shaft 21 to rotate.

[0058] Specifically, the driving motor 26 generates a driving force, and at the same time, the speed changer 25 can be used to realize speed changing as needed, thereby driving the sealed rotating shaft 21 to rotate, and the sealing limiting piece 23 ensures the sealing effect between the sealed rotating shaft 21 and the shell 1, the reaction cavity 11 and the connecting cover 2 when the sealed rotating shaft 21 rotates, thereby ensuring the stirring effect of the materials in the reaction cavity 11.

[0059] In one example of the present application, the lower end of the driving mechanism 20 is further provided with a plurality of locking members 24, through which the driving mechanism 20 can be fixed in position with the outside, ensuring that no deviation occurs during stirring.

[0060] In another example of the present application, the lower end of the shell 1 is further provided with a plurality of bases 8, and the lower end side of the shell 1 is provided with a discharge port 9, through which the last small-particle-diameter catalyst can be discharged after being precipitated at the bottom. Of course, manual or mechanical discharge of the precipitate can be used according to production needs, facilitating subsequent recycling and reuse.

[0061] Further, as a preferred embodiment of the present application, the lower part of the shell 1 can be further provided with a slag removal mechanism 27 for removing the material accumulated at the bottom of the shell 1.

[0062] In one example of the present application, of course, whether to provide the slag removal mechanism 27 can be selected as needed. When the slag removal mechanism 27 is used, specifically, the smaller-particle-diameter catalyst is circulated after passing through the screening of the flow limiting mechanism 12, and the last small-particle-diameter catalyst is precipitated at the bottom and discharged through the pipeline. The accumulated small-particle-diameter catalyst can also be removed by the slag removal mechanism 27 after the reaction is completed according to production needs.

[0063] Further, as a preferred embodiment of the present application, the slag removal mechanism 27 includes a fixing member 28 and a built-in drive 29 arranged inside the fixing member 28, and the output end of the built-in drive 29 is connected to a cleaning brush 31 through a telescopic shaft 30. Through the driving of the built-in drive 29, the movement of the cleaning brush 31 can be achieved, so that the material accumulated at the bottom of the shell 1 can be collected and recycled.

[0064] Specifically, the built-in drive 29 can be a motor product that produces a rotating effect, and can be a direct current motor, an asynchronous motor or a synchronous motor, which can be selected according to actual needs, and is not limited here, as long as it can drive the telescopic shaft 30 to rotate. A servo motor that can be used in a liquid environment can be used in the prior art, of course. The built-in drive 29 can also be a telescopic rod that produces a telescopic motion, or other existing telescopic mechanism products that can be used in a liquid environment, which can further drive the telescopic shaft 30 and the cleaning brush 31 to move left and right reciprocally, so as to clean and remove the material at the bottom.

[0065] In one example of the present application, both the motor product that produces a rotating effect and the existing telescopic mechanism product that produces a telescopic motion can be used at the same time, which can further drive the telescopic shaft 30 and the cleaning brush 31 to rotate and move left and right reciprocally, so as to clean and remove the material at the bottom, improving the cleaning effect.

[0066] In still another example of the present application, the telescopic rod can be a telescopic hollow cylindrical rod rolled from a metal strip or a plastic sheet, and the specific model can be selected according to requirements, which is not limited here. The telescopic rod drives the telescopic shaft 30 and the cleaning brush 31 to move back and forth left and right, so that the material at the bottom can be cleaned and removed, avoiding long-term accumulation of the material.

[0067] Further, as a preferred embodiment of the present application, the cleaning brush 31 comprises a connecting clamping groove 33 for connecting with the telescopic shaft 30, and an annular brush body 32 is arranged outside the connecting clamping groove 33. Of course, other types of brush bodies 32 can also be arranged according to requirements. Since the connecting clamping groove 33 is provided, the appropriate type of cleaning brush 31 can be replaced according to requirements, which is simple and convenient.

[0068] The implementation principle of the embodiment is as follows: during the reaction, the reactant and the catalyst are placed in the reaction cavity 11 to perform catalytic reaction, and at the same time, the intermittent stirring is realized by the stirring assembly. After the catalyst particle size is broken into smaller particle size by the stirring of the stirring assembly, the smaller particle size catalyst can be filtered into the circulating cavity 10 through the flow limiting mechanism 12, that is, under the agitation of the stirring assembly, a rotating material flow path is formed, so that a certain impact force is generated to impact the flow limiting mechanism 12 and open the opening of the flow limiting mechanism 12. After the catalyst particle size is broken into smaller particle size by the stirring of the stirring assembly, the smaller particle size catalyst can pass through the opening of the flow limiting mechanism 12 and flow into the circulating cavity 10, so as to realize the control of the catalyst particle size. After the stirring is stopped, the larger particle size catalyst particles that do not pass through the opening of the flow limiting mechanism 12 will fall back to the bottom of the reaction cavity 11 due to gravity and participate in the catalytic reaction.

[0069] The electrical appliances appearing in the text can be connected with the main controller of the outside world, and the main controller can be a computer or other conventional known device that can be controlled.

[0070] In the description of the present application, it should be noted that, unless otherwise explicitly specified and limited, the terms "mounting", "connection" and "connection" should be understood in a broad sense. For example, it can be fixedly connected, or it can be detachably connected, or integrally connected. It can be mechanically connected, or it can be electrically connected. It can be directly connected, or it can be indirectly connected through an intermediate medium. It can be the communication inside two elements. For those skilled in the art, the specific meaning of the above terms in the present application can be understood according to the specific circumstances.

[0071] It needs to be further explained that in this paper, the term "including", "containing" or any other variant thereof is intended to cover non-exclusive containing, so that the process, method, article or equipment including a series of elements not only includes those elements, but also includes other elements not explicitly listed, or also includes elements inherent to such process, method, article or equipment. Without more limitation. The statement "including a limited element does not exclude the existence of another same element in the process, method, article or equipment including the element". The standard parts used in the present application can be purchased from the market, and the special-shaped parts can be ordered according to the description and drawings. The specific connection mode of each part can adopt the conventional means such as bolt, rivet and welding in the prior art, which will not be described in detail here.

[0072] The basic principles, main features and advantages of the present application are shown and described above. Those skilled in the art should understand that the present application is not limited by the above examples, and the above examples and descriptions in the specification are only preferred examples of the present application and are not intended to limit the present application. Without departing from the spirit and scope of the present application, various changes and improvements can be made to the present application, and these changes and improvements all fall within the scope of the claimed present application. The scope of protection of the present application is defined by the appended claims and their equivalents.

Claims

1. A catalytic reaction apparatus for processing fluoropyrimidine amide derivatives, comprising a housing (1) for placing a reaction material, characterized in that, The catalytic reaction device for processing fluoropyridine amide derivatives further comprises: a reaction cavity (11) arranged inside the shell (1) for accommodating reaction materials and adding catalysts for catalytic reaction, and a circulation cavity (10) formed between the shell (1) and the reaction cavity (11); a stirring assembly arranged in the reaction cavity (11) for stirring the reaction materials in the reaction cavity (11); and a plurality of flow limiting mechanisms (12) uniformly arranged on the side of the shell of the reaction cavity (11) facing the circulation cavity (10) for limiting the one-way passage of catalysts with a certain particle size.

2. The catalytic reaction apparatus for processing fluoropyridine amide derivatives according to claim 1, wherein The flow limiting mechanism (12) comprises a pipe body (13) and a discharge cavity (14) arranged in the pipe body (13), and a movable part (15) is arranged at the end of the pipe body (13) away from the shell of the reaction cavity (11).

3. The catalytic reaction apparatus for processing fluoropyridine amide derivatives according to claim 2, characterized by The flow limiting mechanism (12) further comprises a screening mechanism (16), and the pipe body (13) is communicated with the reaction cavity (11) through the screening mechanism (16).

4. The catalytic reaction apparatus for processing fluoropyridine amide derivatives according to claim 3, characterized by The screening mechanism (16) comprises a connecting pipe (17) for communication with the pipe body (13), and a blocking part (19) is arranged in the connecting pipe (17), and a plurality of screen holes (18) are formed between the blocking part (19) and the inner wall of the connecting pipe (17).

5. The catalytic reaction apparatus for processing fluoropyridine amide derivatives according to claim 4, characterized by A connecting cover (2) is arranged at the opening of one end of the shell (1), a communication port (3) for mounting the stirring assembly is arranged in the middle of the connecting cover (2), and the output end of the stirring assembly penetrates through the communication port (3) and extends into the reaction cavity (11).

6. The catalytic reaction apparatus for processing fluoropyridine amide derivatives according to claim 5, wherein The catalytic reaction device for processing fluoropyridine amide derivatives further comprises a feeding port (4) communicated with the reaction cavity (11).

7. The catalytic reaction apparatus for processing fluoropyridine amide derivatives according to claim 6, wherein The catalytic reaction device for processing fluoropyridine amide derivatives further comprises a first circulation pipeline (5) and a second circulation pipeline (6), the first circulation pipeline (5) is communicated with the circulation cavity (10), the second circulation pipeline (6) is communicated with the reaction cavity (11), and a pump body (7) for communication with the first circulation pipeline (5) and the second circulation pipeline (6) respectively is arranged outside the shell (1).

8. The catalytic reaction apparatus for processing fluoropyridine amide derivatives according to claim 7, characterized by The stirring assembly comprises a driving mechanism (20), a sealing rotating shaft (21) is arranged at the output end of the driving mechanism (20), one end of the sealing rotating shaft (21) extends into the reaction cavity (11), and a plurality of stirring parts (22) are arranged on the part of the sealing rotating shaft (21) in the reaction cavity (11).

9. A catalytic reaction apparatus for processing a fluoropyrimidine amide derivative according to any one of claims 1 to 8, characterized by A slag removal mechanism (27) for removing accumulated materials at the bottom of the shell (1) is arranged at the lower part of the shell (1).

10. The catalytic reaction apparatus for processing fluoropyridine amide derivatives according to claim 9, wherein The slag removal mechanism (27) comprises a fixed part (28) and an internal driver (29) arranged in the fixed part (28), and a cleaning brush (31) is connected to the output end of the internal driver (29) through a telescopic shaft (30).

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