A method and device based on tissue harmonic imaging optimization

Abstract

The present invention provides a method and device based on tissue harmonic imaging optimization, including: S1: in the process of medical detection imaging, continuously sending pulses with the same pulse frequency and a phase difference of 180 degrees to obtain a pulse signal; S2: collecting the voltage values ​​of the positive and negative pulses of the pulse signal, and determining the positive pulse area and the negative pulse area based on the absolute value of the positive pulse voltage, the absolute value of the negative pulse voltage and the pulse emission time length; S3: determining the supplementary pulse type and the number of supplementary pulses based on the area difference between the positive pulse area and the negative pulse area; S4: outputting a medical ultrasound image based on the supplementary pulse type and the number of supplementary pulses; through this method, the image quality of harmonic imaging can be optimized, the influence of the difference between positive and negative pulses on the image can be eliminated, the imaging quality can be improved, it is beneficial for doctors to make a diagnosis, and the risk of doctors misjudgment due to image quality can be reduced.

Description

Technical Field

[0001] The present invention relates to the technical field of image processing, and in particular to a method and a device based on tissue harmonic imaging optimization. Background Art

[0002] Ultrasound imaging is generally used by doctors to observe the internal tissue structure of the human body. Doctors place the probe on the skin surface corresponding to the human body part to obtain an ultrasound image of the part. Ultrasound imaging has become the main auxiliary means of diagnosis for doctors due to its safety, convenience, non-destructiveness and low cost.

[0003] In the field of ultrasound imaging, harmonic imaging has better spatial resolution and contrast. There are three common methods for tissue harmonic extraction, namely bandpass filtering imaging, pulse inversion harmonic imaging and pulse amplitude modulation harmonic imaging.

[0004] The present invention is optimized based on the principle of pulse inversion harmonic imaging. In this imaging process, two pulses are sent continuously with the same pulse frequency and a phase difference of 180 degrees. The two received pulse signals are added. After addition, theoretically, the fundamental wave and odd harmonics cancel each other out, and the even harmonics become twice the original and are enhanced. The imaging effect is best when the positive pulse and the negative pulse have equal areas and can be just offset by addition. However, in actual application, due to various factors such as the nonlinearity of the ultrasonic system hardware, there are inevitably some deviations between the pulse and the negative pulse, which will lead to a decrease in image quality and bring inconvenience to doctors' diagnosis. Summary of the invention

[0005] The present invention provides a method and device based on tissue harmonic imaging optimization, which are used to solve the problems raised in the background technology.

[0006] A method based on tissue harmonic imaging optimization, comprising:

[0007] S1: In the process of medical imaging, pulses with the same pulse frequency and a phase difference of 180 degrees are continuously sent to obtain pulse signals;

[0008] S2: collecting the voltage values ​​of the positive and negative pulses of the pulse signal, and determining the positive pulse area and the negative pulse area based on the absolute value of the positive pulse voltage, the absolute value of the negative pulse voltage and the pulse emission time length;

[0009] S3: determining the type of supplementary pulse and the number of supplementary pulses based on the area difference between the positive pulse area and the negative pulse area;

[0010] S4: Based on the supplementary pulse type and the number of supplementary pulses, a medical ultrasound image is output.

[0011] Preferably, the pulse frequency in S1 is determined as follows:

[0012] Based on the medical diagnosis feature, determine the medical diagnosis accuracy, and determine the image accuracy of the medical ultrasound image according to the medical diagnosis accuracy;

[0013] The pulse frequency is determined based on the correlation between the pulse frequency and the image accuracy.

[0014] Preferably, in S2, collecting the voltage values ​​of the positive and negative pulses of the pulse signal includes:

[0015] Determine the acquisition granularity pre-configured by the analog front-end chip and determine the number of acquisition granularities;

[0016] Based on the acquisition granularity and its corresponding quantity, the sampling channel of the analog front-end chip is allocated to the pulse signal;

[0017] The positive and negative pulses of the pulse signal are collected according to the assigned sampling channels, and the voltage values ​​of the positive and negative pulses are determined based on the collection results.

[0018] In this embodiment, the acquisition granularity is the period of the acquisition pulse signal.

[0019] Preferably, in S2, determining the positive pulse area and the negative pulse area based on the absolute value of the positive pulse voltage, the absolute value of the negative pulse voltage and the pulse emission time length includes:

[0020] The product of the absolute value of the positive pulse voltage and the pulse emission time length is taken as the positive pulse area;

[0021] The product of the absolute value of the negative pulse voltage and the pulse emission time length is taken as the negative pulse area.

[0022] Preferably, in S3, determining the type of supplementary pulse and the number of supplementary pulses based on the area difference between the positive pulse area and the negative pulse area includes:

[0023] Determine whether the area difference between the positive pulse area and the negative pulse area is equal to zero;

[0024] If so, it is determined that pulse supplementation is not necessary;

[0025] Otherwise, it is determined that pulse supplementation is required, and when the area difference between the positive pulse area and the negative pulse area is greater than zero, the supplementary pulse type is determined to be negative pulse supplementation, otherwise, the supplementary pulse type is determined to be positive pulse supplementation;

[0026] Based on the absolute value of the area difference, the pulse supplement number under the supplement pulse type is determined.

[0027] Preferably, determining the pulse supplement quantity under the supplement pulse type based on the absolute value of the area difference comprises:

[0028] When the supplementary pulse type is determined to be positive pulse supplementation, the number of supplementary positive pulses is the value of the ratio of the absolute value of the area difference to the absolute value of the positive pulse voltage rounded up;

[0029] When the supplementary pulse type is determined to be negative pulse supplementation, the number of supplementary negative pulses is the value rounded up to the integer of the ratio of the absolute value of the area difference to the absolute value of the negative pulse voltage.

[0030] Preferably, in S4, outputting a medical ultrasound image based on the supplementary pulse type and the number of supplementary pulses includes:

[0031] In the process of imaging using the pulse signal, a compensation pulse signal according to the type and number of supplementary pulses is added to obtain ultrasonic image data;

[0032] The imaging quality is evaluated based on the ultrasound image data, and according to the evaluation results, the subsequent imaging process using the pulse signal is corrected to finally obtain a medical ultrasound image.

[0033] Preferably, based on the acquisition granularity and its corresponding quantity, the sampling channels of the analog front-end chip are allocated, including:

[0034] Determine the number of sampling channels of the analog front-end chip;

[0035] Based on the acquisition granularity and its corresponding quantity, all acquisition granularities are matched to corresponding sampling channels for the pulse signal in order with the acquisition granularity as a unit to obtain a first matching result;

[0036] Determine a first sampling channel corresponding to the positive pulse and a second sampling channel corresponding to the pulse based on the first matching result, and judge whether a channel sampling feature in the first sampling channel is consistent with a channel sampling feature in the second sampling channel;

[0037] If so, based on the first matching result, assigning a sampling channel of the analog front-end chip to the pulse signal;

[0038] Otherwise, the first matching result is adjusted based on the feature difference between the channel sampling features in the first sampling channel and the channel sampling features in the second sampling channel to obtain a second matching result, and based on the second matching result, a sampling channel of the analog front-end chip is allocated to the pulse signal.

[0039] Preferably, adjusting the first matching result to obtain the second matching result based on the feature difference between the channel sampling feature in the first sampling channel and the channel sampling feature in the second sampling channel includes:

[0040] Determine a channel selection difference and a sampling interval difference from the feature difference, make a first adjustment to the channel allocation in the first matching result based on the channel selection difference, and make a second adjustment to the channel allocation order in the first matching result based on the sampling interval difference;

[0041] Based on the first adjustment and the second adjustment, a second matching result is obtained.

[0042] Preferably, the imaging quality is evaluated based on the ultrasound image data, and according to the evaluation result, the subsequent imaging process using the pulse signal is corrected to finally obtain the medical ultrasound image, including:

[0043] Based on standard ultrasound image data corresponding to the standard medical ultrasound image, the imaging quality is evaluated based on the ultrasound image data to obtain an evaluation result;

[0044] Based on the evaluation results, determine whether the ultrasound image data meets the medical diagnosis requirements;

[0045] If so, no correction is made to the subsequent imaging process using the pulse signal;

[0046] Otherwise, the correction features are determined according to the abnormal ultrasound image data that does not meet the medical diagnosis requirements in the evaluation results, and the subsequent imaging process using the pulse signal is corrected based on the correction features to finally obtain a medical ultrasound image.

[0047] Preferably, a device based on tissue harmonic imaging optimization comprises:

[0048] The pulse sending module is used to continuously send pulses with the same pulse frequency and a phase difference of 180 degrees to obtain a pulse signal during the medical detection imaging process;

[0049] A pulse analysis module, used to collect the voltage values ​​of the positive and negative pulses of the pulse signal, and determine the positive pulse area and the negative pulse area based on the absolute value of the positive pulse voltage, the absolute value of the negative pulse voltage and the pulse emission time length;

[0050] a quantity determination module, for determining the type of supplementary pulses and the quantity of supplementary pulses based on the area difference between the positive pulse area and the negative pulse area;

[0051] The supplementary output module is used to output a medical ultrasound image based on the supplementary pulse type and the supplementary pulse quantity.

[0052] Compared with the prior art, the present invention has achieved the following beneficial effects:

[0053] By continuously sending pulses with the same pulse frequency and a phase difference of 180 degrees during medical detection imaging, a pulse signal is obtained to realize pulse inversion harmonic imaging, which provides a basis for obtaining medical ultrasound images. Then, the voltage values ​​of the positive and negative pulses of the pulse signal are collected, and the positive pulse area and the negative pulse area are determined based on the absolute value of the positive pulse voltage, the absolute value of the negative pulse voltage and the pulse emission time length. The supplementary pulse type and the supplementary pulse number are determined based on the area difference between the positive pulse area and the negative pulse area. Based on the supplementary pulse type and the supplementary pulse number, a medical ultrasound image is output. This method can optimize the image quality of harmonic imaging, eliminate the influence of the difference between positive and negative pulses on the image, improve the imaging quality, facilitate doctors to make diagnoses, and reduce the risk of doctors misjudgment due to image quality.

[0054] Other features and advantages of the present invention will be described in the following description, and partly become apparent from the description, or understood by practicing the present invention. The purpose and other advantages of the present invention can be realized and obtained by the structures particularly pointed out in the written description, claims, and drawings.

[0055] The technical solution of the present invention is further described in detail below through the accompanying drawings and embodiments. BRIEF DESCRIPTION OF THE DRAWINGS

[0056] The accompanying drawings are used to provide a further understanding of the present invention and constitute a part of the specification. Together with the embodiments of the present invention, they are used to explain the present invention and do not constitute a limitation of the present invention. In the accompanying drawings:

[0057] Figure 1 It is a flow chart of a method based on tissue harmonic imaging optimization in an embodiment of the present invention;

[0058] Figure 2 This is a flow chart of collecting the voltage values ​​of positive and negative pulses in an embodiment of the present invention;

[0059] Figure 3 A flowchart of outputting a medical ultrasound image in an embodiment of the present invention;

[0060] Figure 4 This is a structural diagram of a device based on tissue harmonic imaging optimization in an embodiment of the present invention. DETAILED DESCRIPTION

[0061] The preferred embodiments of the present invention are described below in conjunction with the accompanying drawings. It should be understood that the preferred embodiments described herein are only used to illustrate and explain the present invention, and are not used to limit the present invention.

[0062] Embodiment 1:

[0063] The embodiment of the present invention provides a method based on tissue harmonic imaging optimization, such as Figure 1 As shown, including:

[0064] S1: In the process of medical imaging, pulses with the same pulse frequency and a phase difference of 180 degrees are continuously sent to obtain pulse signals;

[0065] S2: collecting the voltage values ​​of the positive and negative pulses of the pulse signal, and determining the positive pulse area and the negative pulse area based on the absolute value of the positive pulse voltage, the absolute value of the negative pulse voltage and the pulse emission time length;

[0066] S3: determining the type of supplementary pulse and the number of supplementary pulses based on the area difference between the positive pulse area and the negative pulse area;

[0067] S4: Based on the supplementary pulse type and the number of supplementary pulses, a medical ultrasound image is output.

[0068] In this embodiment, the supplementary pulse type is positive pulse compensation or negative pulse supplement.

[0069] In this embodiment, the product of the absolute value of the voltage and the pulse emission time length is the pulse area.

[0070] The beneficial effect of the above design scheme is: by continuously sending pulses with the same pulse frequency and a phase difference of 180 degrees during the medical detection imaging process, a pulse signal is obtained to realize pulse inversion harmonic imaging, which provides a basis for the acquisition of medical ultrasound images, and then the voltage values ​​of the positive and negative pulses of the pulse signal are collected, and the positive pulse area and the negative pulse area are determined based on the absolute value of the positive pulse voltage, the absolute value of the negative pulse voltage and the pulse emission time length, and the supplementary pulse type and the supplementary pulse number are determined based on the area difference between the positive pulse area and the negative pulse area, and the medical ultrasound image is output based on the supplementary pulse type and the supplementary pulse number. Through this method, the image quality of harmonic imaging can be optimized, the influence of the difference between positive and negative pulses on the image can be eliminated, the imaging quality can be improved, it is beneficial for doctors to make diagnoses, and the risk of doctors misjudgment due to image quality can be reduced.

[0071] Embodiment 2:

[0072] Based on Example 1, the present invention provides a method based on tissue harmonic imaging optimization. The method for determining the pulse frequency in S1 is as follows:

[0073] Based on the medical diagnosis feature, determine the medical diagnosis accuracy, and determine the image accuracy of the medical ultrasound image according to the medical diagnosis accuracy;

[0074] The pulse frequency is determined based on the correlation between the pulse frequency and the image accuracy.

[0075] The beneficial effects of the above design scheme are: by determining the medical diagnosis accuracy based on the medical diagnosis characteristics, and determining the image accuracy of the medical ultrasound image based on the medical diagnosis accuracy; based on the correlation between the pulse frequency and the image accuracy, the pulse frequency is determined, so that the image quality of the medical ultrasound image obtained at the pulse frequency better meets the needs of medical diagnosis.

[0076] Embodiment 3:

[0077] Based on Example 1, the present invention provides a method based on tissue harmonic imaging optimization, such as Figure 2 As shown, in S2, the voltage values ​​of the positive and negative pulses of the pulse signal are collected, including:

[0078] Determine the acquisition granularity pre-configured by the analog front-end chip and determine the number of acquisition granularities;

[0079] Based on the acquisition granularity and its corresponding quantity, the sampling channel of the analog front-end chip is allocated to the pulse signal;

[0080] The positive and negative pulses of the pulse signal are collected according to the assigned sampling channels, and the voltage values ​​of the positive and negative pulses are determined based on the collection results.

[0081] In this embodiment, the acquisition granularity is the period of the acquisition pulse signal.

[0082] In this embodiment, all numbers of acquisition granularities are accumulated to achieve the acquisition of all pulse echo signals.

[0083] In this embodiment, the analog front-end chip capital includes multiple sampling channels.

[0084] The beneficial effects of the above design scheme are: by allocating sampling channels of the analog front-end chip to the pulse signal based on the acquisition granularity and its corresponding quantity; collecting the positive and negative pulses of the pulse signal according to the allocated sampling channels, and determining the voltage values ​​of the positive and negative pulses based on the acquisition results, reducing sampling errors, and ensuring the accuracy of the voltage values ​​of the positive and negative pulses.

[0085] Embodiment 4:

[0086] Based on Example 1, the embodiment of the present invention provides a method based on tissue harmonic imaging optimization, in S2, based on the absolute value of the positive pulse voltage, the absolute value of the negative pulse voltage and the pulse emission time length, the positive pulse area and the negative pulse area are determined, including:

[0087] The product of the absolute value of the positive pulse voltage and the pulse emission time length is taken as the positive pulse area;

[0088] The product of the absolute value of the negative pulse voltage and the pulse emission time length is taken as the negative pulse area.

[0089] The beneficial effect of the above design is that the pulse area is obtained by taking the product of the absolute value of the positive pulse voltage and the pulse emission time length as the positive pulse area and taking the product of the absolute value of the negative pulse voltage and the pulse emission time length as the negative pulse area.

[0090] Embodiment 5:

[0091] Based on Example 1, the embodiment of the present invention provides a method based on tissue harmonic imaging optimization. In S3, based on the area difference between the positive pulse area and the negative pulse area, the type of supplementary pulse and the number of supplementary pulses are determined, including:

[0092] Determine whether the area difference between the positive pulse area and the negative pulse area is equal to zero;

[0093] If so, it is determined that pulse supplementation is not necessary;

[0094] Otherwise, it is determined that pulse supplementation is required, and when the area difference between the positive pulse area and the negative pulse area is greater than zero, the supplementary pulse type is determined to be negative pulse supplementation, otherwise, the supplementary pulse type is determined to be positive pulse supplementation;

[0095] Based on the absolute value of the area difference, the pulse supplement number under the supplement pulse type is determined.

[0096] The beneficial effect of the above design scheme is: the type of supplementary pulse is determined by judging the size of the area difference between the positive pulse area and the negative pulse area and zero, and based on the absolute value of the area difference, the number of pulse supplements under the supplementary pulse type is determined, thereby optimizing the image quality of harmonic imaging, eliminating the impact of the difference between positive and negative pulses on the image, and improving the imaging quality.

[0097] Embodiment 6:

[0098] Based on Example 5, the embodiment of the present invention provides a method based on tissue harmonic imaging optimization, which determines the number of pulse supplements under the supplementary pulse type based on the absolute value of the area difference, including:

[0099] When the supplementary pulse type is determined to be positive pulse supplementation, the number of supplementary positive pulses is the value of the ratio of the absolute value of the area difference to the absolute value of the positive pulse voltage rounded up;

[0100] When the supplementary pulse type is determined to be negative pulse supplementation, the number of supplementary negative pulses is the value rounded up to the integer of the ratio of the absolute value of the area difference to the absolute value of the negative pulse voltage.

[0101] The beneficial effect of the above design scheme is: providing a method for determining the number of pulse supplements under the supplementary pulse type, providing a data basis for image optimization.

[0102] Embodiment 7:

[0103] Based on Example 1, the present invention provides a method based on tissue harmonic imaging optimization, such as Figure 3 As shown, in S4, based on the supplementary pulse type and the number of supplementary pulses, a medical ultrasound image is output, including:

[0104] In the process of imaging using the pulse signal, a compensation pulse signal according to the type and number of supplementary pulses is added to obtain ultrasonic image data;

[0105] The imaging quality is evaluated based on the ultrasound image data, and according to the evaluation results, the subsequent imaging process using the pulse signal is corrected to finally obtain a medical ultrasound image.

[0106] The beneficial effect of the above design scheme is: by adding a compensation pulse signal according to the type and number of supplementary pulses in the process of imaging using the pulse signal, ultrasonic image data is obtained;

[0107] The imaging quality is evaluated based on the ultrasound image data, and the subsequent imaging process using the pulse signal is corrected according to the evaluation results, and finally a medical ultrasound image is obtained. This method can optimize the image quality of harmonic imaging, eliminate the impact of the difference between positive and negative pulses on the image, improve the imaging quality, facilitate doctors' diagnosis, and reduce the risk of doctors' misjudgment due to image quality.

[0108] Embodiment 8:

[0109] Based on Example 3, the embodiment of the present invention provides a method based on tissue harmonic imaging optimization, which allocates sampling channels of an analog front-end chip based on acquisition granularity and its corresponding quantity, including:

[0110] Determine the number of sampling channels of the analog front-end chip;

[0111] Based on the acquisition granularity and its corresponding quantity, all acquisition granularities are matched to corresponding sampling channels for the pulse signal in order with the acquisition granularity as a unit to obtain a first matching result;

[0112] Determine a first sampling channel corresponding to the positive pulse and a second sampling channel corresponding to the pulse based on the first matching result, and judge whether a channel sampling feature in the first sampling channel is consistent with a channel sampling feature in the second sampling channel;

[0113] If so, based on the first matching result, assigning a sampling channel of the analog front-end chip to the pulse signal;

[0114] Otherwise, the first matching result is adjusted based on the feature difference between the channel sampling features in the first sampling channel and the channel sampling features in the second sampling channel to obtain a second matching result, and based on the second matching result, a sampling channel of the analog front-end chip is allocated to the pulse signal.

[0115] In this embodiment, all acquisition granularities are matched to corresponding sampling channels for pulse signals in order, and the sampling channels are numbered, and channels are provided for the acquisition granularities in sequence according to the numbering order.

[0116] The beneficial effect of the above design scheme is: by matching the corresponding sampling channels for the pulse signal in order according to all the acquisition granularities, a first matching result is obtained to realize the allocation of sampling channels, and then based on the first matching result, the first sampling channel corresponding to the positive pulse and the second sampling channel corresponding to the pulse are determined, and it is judged whether the channel sampling characteristics in the first sampling channel are consistent with the channel sampling characteristics in the second sampling channel; if so, based on the first matching result, the sampling channel of the analog front-end chip is allocated to the pulse signal; otherwise, based on the feature difference between the channel sampling characteristics in the first sampling channel and the channel sampling characteristics in the second sampling channel, the first matching result is adjusted to obtain a second matching result, and based on the second matching result, the sampling channel of the analog front-end chip is allocated to the pulse signal, so as to realize accurate allocation of sampling channels and provide a basis for realizing accurate acquisition of pulse voltage values.

[0117] Embodiment 9:

[0118] Based on Example 8, the embodiment of the present invention provides a method based on tissue harmonic imaging optimization, which adjusts the first matching result based on the feature difference between the channel sampling feature in the first sampling channel and the channel sampling feature in the second sampling channel to obtain a second matching result, including:

[0119] Determine a channel selection difference and a sampling interval difference from the feature difference, make a first adjustment to the channel allocation in the first matching result based on the channel selection difference, and make a second adjustment to the channel allocation order in the first matching result based on the sampling interval difference;

[0120] Based on the first adjustment and the second adjustment, a second matching result is obtained.

[0121] In this embodiment, the channel selection difference is that the channel selection ratio between positive and negative pulses is not equal, which will affect the acquisition accuracy.

[0122] In this embodiment, the sampling interval difference is the difference in channel acquisition sequence between positive and negative pulses, and an unbalanced sequence will also affect the acquisition accuracy.

[0123] The beneficial effects of the above design scheme are: by determining the channel selection difference and the sampling interval difference from the feature difference, a first adjustment is made to the channel allocation itself in the first matching result based on the channel selection difference, and a second adjustment is made to the channel allocation order in the first matching result based on the sampling interval difference; based on the first adjustment and the second adjustment, a second matching result is obtained, and accurate allocation of sampling channels is achieved, providing a basis for achieving accurate collection of pulse voltage values.

[0124] Embodiment 10:

[0125] Based on Example 7, the embodiment of the present invention provides a method based on tissue harmonic imaging optimization, which evaluates the imaging quality based on ultrasound image data, and corrects the subsequent imaging process using pulse signals according to the evaluation results, and finally obtains a medical ultrasound image, including:

[0126] Based on standard ultrasound image data corresponding to the standard medical ultrasound image, the imaging quality is evaluated based on the ultrasound image data to obtain an evaluation result;

[0127] Based on the evaluation results, determine whether the ultrasound image data meets the medical diagnosis requirements;

[0128] If so, no correction is made to the subsequent imaging process using the pulse signal;

[0129] Otherwise, the correction features are determined according to the abnormal ultrasound image data that does not meet the medical diagnosis requirements in the evaluation results, and the subsequent imaging process using the pulse signal is corrected based on the correction features to finally obtain a medical ultrasound image.

[0130] In this embodiment, the subsequent imaging process using the pulse signal is corrected based on the correction feature, for example, the pulse voltage value determination method and the pulse area calculation process are corrected.

[0131] The beneficial effects of the above design scheme are: based on the standard ultrasound image data corresponding to the standard medical ultrasound image, the imaging quality is evaluated based on the ultrasound image data to obtain an evaluation result; based on the evaluation result, it is determined whether the ultrasound image data meets the medical diagnosis requirements; if so, the subsequent imaging process using the pulse signal is not corrected; otherwise, the correction features are determined according to the abnormal ultrasound image data that does not meet the medical diagnosis requirements in the evaluation results, and the subsequent imaging process using the pulse signal is corrected based on the correction features to finally obtain a medical ultrasound image. By means of evaluation and correction at the same time, the medical ultrasound image is optimized and the imaging quality is improved, which is beneficial for doctors to make a diagnosis and reduces the risk of doctors misjudgment due to image quality.

[0132] Embodiment 11:

[0133] Based on the method based on tissue harmonic imaging optimization described in any one of embodiments 1-10, a device based on tissue harmonic imaging optimization is provided, such as Figure 4 As shown, including:

[0134] The pulse sending module is used to continuously send pulses with the same pulse frequency and a phase difference of 180 degrees to obtain a pulse signal during the medical detection imaging process;

[0135] A pulse analysis module, used to collect the voltage values ​​of the positive and negative pulses of the pulse signal, and determine the positive pulse area and the negative pulse area based on the absolute value of the positive pulse voltage, the absolute value of the negative pulse voltage and the pulse emission time length;

[0136] a quantity determination module, for determining the type of supplementary pulses and the quantity of supplementary pulses based on the area difference between the positive pulse area and the negative pulse area;

[0137] The supplementary output module is used to output a medical ultrasound image based on the supplementary pulse type and the supplementary pulse quantity.

[0138] In this embodiment, the supplementary pulse type is positive pulse compensation or negative pulse supplement.

[0139] In this embodiment, the product of the absolute value of the voltage and the pulse emission time length is the pulse area.

[0140] In this embodiment, the device based on tissue harmonic imaging optimization also includes a pulse receiving module, which is used to receive the pulse signal obtained by the pulse sending module, and send it to the pulse analysis module for signal analysis after being processed by the signal processing module. It also includes an image display module for displaying the medical ultrasound image obtained by the supplementary output module. For the integrity of the device, the pulse receiving module, the signal processing module and the supplementary output module are conventional and necessary design features of the ultrasound device and are explained here.

[0141] The beneficial effect of the above design scheme is: by continuously sending pulses with the same pulse frequency and a phase difference of 180 degrees during the medical detection imaging process, a pulse signal is obtained to realize pulse inversion harmonic imaging, which provides a basis for the acquisition of medical ultrasound images, and then the voltage values ​​of the positive and negative pulses of the pulse signal are collected, and the positive pulse area and the negative pulse area are determined based on the absolute value of the positive pulse voltage, the absolute value of the negative pulse voltage and the pulse emission time length, and the supplementary pulse type and the supplementary pulse number are determined based on the area difference between the positive pulse area and the negative pulse area, and the medical ultrasound image is output based on the supplementary pulse type and the supplementary pulse number. Through this method, the image quality of harmonic imaging can be optimized, the influence of the difference between positive and negative pulses on the image can be eliminated, the imaging quality can be improved, it is beneficial for doctors to make diagnoses, and the risk of doctors misjudgment due to image quality can be reduced.

[0142] Obviously, those skilled in the art can make various changes and modifications to the present invention without departing from the spirit and scope of the present invention. Thus, if these modifications and variations of the present invention fall within the scope of the claims of the present invention and their equivalents, the present invention is also intended to include these modifications and variations.

Claims

1. A method based on tissue harmonic imaging optimization, characterized in that: include: S1: In the process of medical imaging, pulses with the same pulse frequency and a phase difference of 180 degrees are continuously sent to obtain pulse signals; S2: collecting the voltage values ​​of the positive and negative pulses of the pulse signal, and determining the positive pulse area and the negative pulse area based on the absolute value of the positive pulse voltage, the absolute value of the negative pulse voltage and the pulse emission time length; S3: determining the type of supplementary pulse and the number of supplementary pulses based on the area difference between the positive pulse area and the negative pulse area; S4: outputting a medical ultrasound image based on the supplementary pulse type and the number of supplementary pulses; In S4, based on the supplementary pulse type and the number of supplementary pulses, a medical ultrasound image is output, including: In the process of imaging using the pulse signal, a compensation pulse signal according to the type and number of supplementary pulses is added to obtain ultrasonic image data; The imaging quality is evaluated based on the ultrasound image data, and according to the evaluation results, the subsequent imaging process using the pulse signal is corrected to finally obtain a medical ultrasound image.

2. The method based on tissue harmonic imaging optimization according to claim 1, characterized in that: The pulse frequency in S1 is determined as follows: Based on the medical diagnosis feature, determine the medical diagnosis accuracy, and determine the image accuracy of the medical ultrasound image according to the medical diagnosis accuracy; The pulse frequency is determined based on the correlation between the pulse frequency and the image accuracy.

3. The method based on tissue harmonic imaging optimization according to claim 1, characterized in that: In S2, the voltage values ​​of the positive and negative pulses of the pulse signal are collected, including: Determine the acquisition granularity pre-configured by the analog front-end chip and determine the number of acquisition granularities; Based on the acquisition granularity and its corresponding quantity, the sampling channel of the analog front-end chip is allocated to the pulse signal; The positive and negative pulses of the pulse signal are collected according to the assigned sampling channels, and the voltage values ​​of the positive and negative pulses are determined based on the collection results.

4. The method based on tissue harmonic imaging optimization according to claim 1, characterized in that: In S2, based on the absolute value of the positive pulse voltage, the absolute value of the negative pulse voltage and the pulse emission time length, the positive pulse area and the negative pulse area are determined, including: The product of the absolute value of the positive pulse voltage and the pulse emission time length is taken as the positive pulse area; The product of the absolute value of the negative pulse voltage and the pulse emission time length is taken as the negative pulse area.

5. The method based on tissue harmonic imaging optimization according to claim 1, characterized in that: In S3, based on the area difference between the positive pulse area and the negative pulse area, determining the type of supplementary pulse and the number of supplementary pulses includes: Determine whether the area difference between the positive pulse area and the negative pulse area is equal to zero; If so, it is determined that pulse supplementation is not necessary; Otherwise, it is determined that pulse supplementation is required, and when the area difference between the positive pulse area and the negative pulse area is greater than zero, the supplementary pulse type is determined to be negative pulse supplementation, otherwise, the supplementary pulse type is determined to be positive pulse supplementation; Based on the absolute value of the area difference, the pulse supplement number under the supplement pulse type is determined.

6. The method based on tissue harmonic imaging optimization according to claim 5, characterized in that: Based on the absolute value of the area difference, the pulse supplement quantity under the supplement pulse type is determined, including: When the supplementary pulse type is determined to be positive pulse supplementation, the number of supplementary positive pulses is the value of the ratio of the absolute value of the area difference to the absolute value of the positive pulse voltage rounded up; When the supplementary pulse type is determined to be negative pulse supplementation, the number of supplementary negative pulses is the value rounded up to the integer of the ratio of the absolute value of the area difference to the absolute value of the negative pulse voltage.

7. The method based on tissue harmonic imaging optimization according to claim 3, characterized in that: Based on the acquisition granularity and its corresponding quantity, the sampling channels of the analog front-end chip are allocated, including: Determine the number of sampling channels of the analog front-end chip; Based on the acquisition granularity and its corresponding quantity, all acquisition granularities are matched to corresponding sampling channels for the pulse signal in order with the acquisition granularity as a unit to obtain a first matching result; Determine a first sampling channel corresponding to the positive pulse and a second sampling channel corresponding to the pulse based on the first matching result, and judge whether a channel sampling feature in the first sampling channel is consistent with a channel sampling feature in the second sampling channel; If so, based on the first matching result, assigning a sampling channel of the analog front-end chip to the pulse signal; Otherwise, the first matching result is adjusted based on the feature difference between the channel sampling features in the first sampling channel and the channel sampling features in the second sampling channel to obtain a second matching result, and based on the second matching result, a sampling channel of the analog front-end chip is allocated to the pulse signal.

8. The method based on tissue harmonic imaging optimization according to claim 7, characterized in that: Adjusting the first matching result based on a feature difference between a channel sampling feature in the first sampling channel and a channel sampling feature in the second sampling channel to obtain a second matching result includes: Determine a channel selection difference and a sampling interval difference from the feature difference, make a first adjustment to the channel allocation in the first matching result based on the channel selection difference, and make a second adjustment to the channel allocation order in the first matching result based on the sampling interval difference; Based on the first adjustment and the second adjustment, a second matching result is obtained.

9. The method based on tissue harmonic imaging optimization according to claim 1, characterized in that: The imaging quality is evaluated based on the ultrasound image data, and the subsequent imaging process using the pulse signal is corrected according to the evaluation results, and finally a medical ultrasound image is obtained, including: Based on standard ultrasound image data corresponding to the standard medical ultrasound image, the imaging quality is evaluated based on the ultrasound image data to obtain an evaluation result; Based on the evaluation results, determine whether the ultrasound image data meets the medical diagnosis requirements; If so, no correction is made to the subsequent imaging process using the pulse signal; Otherwise, the correction features are determined according to the abnormal ultrasound image data that does not meet the medical diagnosis requirements in the evaluation results, and the subsequent imaging process using the pulse signal is corrected based on the correction features to finally obtain a medical ultrasound image.

10. According to the method based on tissue harmonic imaging optimization according to any one of claims 1 to 9, a device based on tissue harmonic imaging optimization is provided, characterized in that: include: The pulse sending module is used to continuously send pulses with the same pulse frequency and a phase difference of 180 degrees to obtain a pulse signal during the medical detection imaging process; A pulse analysis module, used to collect the voltage values ​​of the positive and negative pulses of the pulse signal, and determine the positive pulse area and the negative pulse area based on the absolute value of the positive pulse voltage, the absolute value of the negative pulse voltage and the pulse emission time length; a quantity determination module, for determining the type of supplementary pulses and the quantity of supplementary pulses based on the area difference between the positive pulse area and the negative pulse area; The supplementary output module is used to output a medical ultrasound image based on the supplementary pulse type and the supplementary pulse quantity.

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