An obstetric amniotic fluid sampling device

Abstract

The present invention relates to the technical field of obstetric medical devices, and particularly relates to an obstetric amniotic fluid sampling device, which comprises a device body, a puncture needle and a negative pressure mechanism. The device body includes a vertically arranged outer cylinder with both ends closed, a primary stage tank, a liquid storage tank, a negative pressure pipe group, a liquid inlet pipe group and a control unit for controlling the on-off of the negative pressure pipe group and the liquid inlet pipe group, which are arranged inside the outer cylinder. The negative pressure mechanism is communicated with the upper inner cavity of the primary stage tank and the upper inner cavity of the liquid storage tank through the negative pressure pipe group. The puncture needle is communicated with the lower inner cavity of the primary stage tank and the lower inner cavity of the liquid storage tank through the liquid inlet pipe group. A sampling pipe is arranged on the liquid storage tank. One end of the sampling pipe is hermetically communicated with the lower inner cavity of the liquid storage tank, and the other end of the sampling pipe extends out of the outer cylinder. A cap for opening or blocking the sampling pipe is arranged at the end of the sampling pipe extending out of the outer cylinder. The operation of the obstetric amniotic fluid sampling device using this solution is simple, and can be operated by one person for sampling and can isolate the primary stage amniotic fluid from the amniotic fluid for subsequent detection.

Description

Technical Field

[0001] The present invention relates to the technical field of obstetric medical devices, and particularly to an obstetric amniotic fluid sampling device. Background Art

[0002] Amniotic fluid examination is mostly carried out during the 16th to 20th week of pregnancy. Through amniocentesis, amniotic fluid is taken for examination to determine the maturity and health status of the fetus, and to diagnose whether the fetus is normal or suffers from certain genetic diseases. During the amniotic fluid sampling process using the puncture method, the front end tube of the puncture needle will carry maternal blood or maternal tissue. When these maternal blood or maternal tissue are drawn along with the amniotic fluid, the obtained sampled amniotic fluid will contain maternal blood or tissue, causing maternal cell contamination of the sampled amniotic fluid, resulting in abnormal test results and misdiagnosis. In order to prevent the occurrence of maternal cell contamination during amniotic fluid puncture sampling, it is necessary to remove the first 2 - 3 milliliters of amniotic fluid during the sampling process to improve the accuracy of the test. The existing amniotic fluid puncture sampling method usually uses a syringe to draw amniotic fluid. The method of removing the first 2 - 3 milliliters of amniotic fluid is usually that after the puncture is successful, the medical staff first uses a 2 - milliliter syringe to draw 2 milliliters of amniotic fluid and then discard it, and then replace it with a new syringe to complete the subsequent amniotic fluid sampling. Since it is necessary to use an ultrasonic probe to constantly detect and monitor the position of the puncture needle during the puncture sampling process to avoid harming the fetus, it is necessary for 1 person to fix the puncture needle and the ultrasonic probe, and another person to replace the syringe and draw the amniotic fluid. Therefore, this amniotic fluid sampling process requires the cooperation of 2 medical staff, with cumbersome operation and a large amount of syringe waste. Summary of the Invention

[0003] Aiming at the deficiencies of the above - mentioned prior art, the technical problem to be solved by the present invention is: to provide an obstetric amniotic fluid sampling device to solve the problems of requiring the cooperation of 2 people, cumbersome operation, and syringe waste when using the existing amniotic fluid sampling device for amniotic fluid sampling as mentioned in the background art.

[0004] To solve the above technical problems, a technical solution adopted by the present invention is: to provide an obstetric amniotic fluid sampling device, including a device body, a puncture needle and a negative pressure mechanism. The device body includes a vertically arranged outer cylinder with both ends closed, a primary stage tank, a liquid storage tank, a negative pressure pipe group, a liquid inlet pipe group and a control unit for controlling the on-off of the negative pressure pipe group and the liquid inlet pipe group arranged inside the outer cylinder. Both the primary stage tank and the liquid storage tank are vertically arranged tanks with both ends closed. The negative pressure mechanism is connected to the upper inner cavity of the primary stage tank and the upper inner cavity of the liquid storage tank through the negative pressure pipe group. The puncture needle is connected to the lower inner cavity of the primary stage tank and the lower inner cavity of the liquid storage tank through the liquid inlet pipe group. A sampling pipe is arranged on the liquid storage tank. One end of the sampling pipe is hermetically connected to the lower inner cavity of the liquid storage tank, and the other end of the sampling pipe extends out of the outer cylinder. A cap for opening or blocking the sampling pipe is arranged at the end of the sampling pipe extending out of the outer cylinder.

[0005] In the above solution, after the puncture needle is correctly punctured with the assistance of an ultrasonic probe, first, the control unit is used to connect the upper inner cavity of the primary stage tank to the negative pressure mechanism and connect the lower inner cavity of the primary stage tank to the puncture needle. The negative pressure mechanism is operated to generate negative pressure so that the primary amniotic fluid enters the primary stage tank. Then, the control unit is used to connect the upper inner cavity of the liquid storage tank to the negative pressure mechanism and connect the lower inner cavity of the liquid storage tank to the puncture needle. The negative pressure mechanism is operated to generate negative pressure so that the amniotic fluid enters the liquid storage tank, achieving the purpose of isolating the primary amniotic fluid from the subsequent detected amniotic fluid. After sampling, the cap is opened to extract the amniotic fluid in the liquid storage tank for cultivation and detection.

[0006] Further, the control unit includes a riser pipe vertically arranged with openings at both ends, a sliding column arranged in the riser pipe and sealingly slidingly connected to the riser pipe, a first piston arranged in the initial stage tank and sealingly slidingly connected to the initial stage tank, a first push rod fixedly connected to the lower end of the first piston and vertically extending out of the initial stage tank at the upper end, a stop rod horizontally arranged with one end fixedly connected to the sliding column and the other end extending out of the riser pipe, a vertical groove corresponding to the stop rod and opened on the side wall of the riser pipe to allow the stop rod to slide along the axial direction of the riser pipe, an upper through hole horizontally penetrating the upper end of the sliding column along the radial direction of the sliding column, a lower through hole horizontally penetrating the lower end of the sliding column along the radial direction of the sliding column, a cavity arranged inside the lower end of the sliding column, an upper through hole arranged on the side wall of the cavity to communicate the upper inner cavity of the cavity with the external space of the sliding column, a lower through hole arranged on the side wall of the cavity to communicate the lower inner cavity of the cavity with the external space of the sliding column, and a first spring arranged at the upper end of the sliding column. The upper end of the first spring is fixedly connected to the top plate of the outer cylinder, the lower end of the first spring is fixedly connected to the upper end surface of the sliding column. An upper air hole is opened on the top plate of the outer cylinder corresponding to the inner cavity of the riser pipe to communicate the upper inner cavity of the riser pipe with the external space of the outer cylinder. A lower air hole is opened on the bottom plate of the outer cylinder corresponding to the inner cavity of the riser pipe to communicate the lower inner cavity of the riser pipe with the external space of the outer cylinder. A one-way valve one allowing only air flow to enter the lower inner cavity of the riser pipe is arranged at the lower air hole. The upper end of the riser pipe is fixedly connected to the top plate of the outer cylinder, and the lower end of the riser pipe is sealingly and fixedly connected to the bottom plate of the outer cylinder;

[0007] The negative pressure pipe group includes a first negative pressure pipe, a first transverse negative pressure pipe, and a second transverse negative pressure pipe coaxially arranged with the first transverse negative pressure pipe. The first negative pressure pipe connects the upper inner cavity of the initial stage tank with the negative pressure mechanism. One end of the first transverse negative pressure pipe is sealingly connected to the inner cavity of the first negative pressure pipe, and the other end of the first transverse negative pressure pipe is sealingly connected to the upper inner cavity of the riser pipe. One end of the second transverse negative pressure pipe is sealingly connected to the upper inner cavity of the riser pipe, and the other end of the second transverse negative pressure pipe is sealingly connected to the upper inner cavity of the liquid storage tank;

[0008] The liquid inlet pipe group includes a first liquid inlet pipe with one end connected to the puncture needle and the other end sealingly connected to the lower inner cavity of the riser pipe, a second liquid inlet pipe with one end sealingly connected to the lower inner cavity of the riser pipe and the other end sealingly connected to the lower inner cavity of the initial stage tank, a liquid inlet bypass pipe located above the first liquid inlet pipe with one end sealingly connected to the middle inner cavity of the first liquid inlet pipe and the other end sealingly connected to the inner cavity of the riser pipe, and a third liquid inlet pipe located above the liquid inlet bypass pipe with one end sealingly connected to the inner cavity of the riser pipe and the other end sealingly connected to the lower inner cavity of the liquid storage tank.

[0009] Further, the negative pressure mechanism includes a cylinder with one end closed. A second piston is hermetically and slidably connected inside the cylinder. A second push rod is arranged along the axis of the cylinder on the second piston. One end of the second push rod is fixedly connected to the second piston, and the other end of the second push rod extends out of the cylinder from the closed end of the cylinder. The second push rod is hermetically and slidably connected to the closed end of the cylinder. The end of the first negative pressure tube away from the initial stage tank communicates with the inner cavity of the closed end of the cylinder.

[0010] Further, an intake air bypass pipe is arranged below the second liquid inlet pipe. One end of the intake air bypass pipe is hermetically connected to the inner cavity of the middle part of the second liquid inlet pipe, and the other end of the intake air bypass pipe is hermetically connected to the inner cavity of the lower part of the riser pipe.

[0011] Further, the end of the first liquid inlet pipe connected to the puncture needle is provided with an external thread, and the outlet end of the puncture needle is provided with an internal thread. The puncture needle is threadedly connected to the first liquid inlet pipe.

[0012] Further, the cylinder is detachably connected to the outer cylinder. The upper end of the first negative pressure tube extends upward out of the outer cylinder. The lower end of the first negative pressure tube is hermetically connected to the upper inner cavity of the initial stage tank. A jack for communicating the inner cavity of the closed end of the cylinder with the external space of the cylinder is arranged on the side wall near the closed end of the cylinder. The upper end of the first negative pressure tube is hermetically inserted into the jack.

[0013] Further, the outer cylinder, the initial stage tank and the liquid storage tank are all made of transparent materials.

[0014] Further, scale lines are provided on the side wall of the liquid storage tank, and a third piston is hermetically and slidably connected inside the liquid storage tank.

[0015] Further, the cylinder is snap-connected to the outer cylinder.

[0016] Compared with the existing method of using a syringe for sampling, which requires at least two people to cooperate for amniotic fluid sampling, the present solution has the beneficial effects that amniotic fluid sampling can be completed by a single person, the operation is simple, the initial stage amniotic fluid can be separated from the subsequent amniotic fluid without the need for others to help replace the syringe during the whole amniotic fluid sampling process, and syringes are saved. BRIEF DESCRIPTION OF THE DRAWINGS

[0017] The drawings described herein are used to provide a further understanding of the present application, and constitute a part of the present application. The illustrative embodiments and descriptions thereof of the present application are used to explain the present application and do not constitute an improper limitation to the present application. In the drawings:

[0018] Figure 1 It is a schematic structural diagram of an embodiment of the present invention.

[0019] Figure 2 Figure 1 Enlarged view of part A.

[0020] Figure 3 Figure 1 Enlarged view of part B.

[0021] Figure 4 It is a schematic structural diagram in a working state of an embodiment of the present invention.

[0022] Figure 5 is Figure 4 Enlarged view of part C.

[0023] The meanings of the reference numerals in the drawings are as follows:

[0024] Device body 10, outer cylinder 101, upper air hole 1011, lower air hole 1012, one-way valve 1013, initial stage tank 102, piston 1021, push rod 1022, liquid storage tank 103, piston 3 1031, sampling tube 1032, cap 1033, puncture needle 20, negative pressure mechanism 30, air cylinder 301, piston 2 302, push rod 2 303, vertical pipe 41, vertical groove 411, sliding column 42, stop rod 421, upper through hole 422, lower through hole 423, cavity 424, upper through hole 425, lower through hole 426, first spring 43, first negative pressure pipe 51, horizontal negative pressure pipe 1 52, horizontal negative pressure pipe 2 53, liquid inlet pipe 1 61, liquid inlet pipe 2 62, liquid inlet pipe 3 63, liquid inlet bypass pipe 64, air inlet bypass pipe 70. Specific embodiments

[0025] In order to make the objectives, technical solutions and advantages of the present application clearer, the technical solutions of the present application will be clearly and completely described below in conjunction with specific embodiments of the present application and the corresponding drawings. Obviously, the described embodiments are only a part of the embodiments of the present application, rather than all the embodiments. Based on the embodiments in the present application, all other embodiments obtained by those of ordinary skill in the art without making creative efforts shall fall within the protection scope of the present application.

[0026] Unless otherwise defined, all technical and scientific terms used herein have the same meaning as commonly understood by those skilled in the technical field to which the present invention belongs. The terms used in the description of the present invention herein are only for the purpose of describing specific embodiments and are not intended to limit the present invention.

[0027] An obstetric amniotic fluid sampling device of this embodiment, such as Figures 1-5As shown in the figure, it includes a device body 10, a puncture needle 20 and a negative pressure mechanism 30. The device body 10 includes a vertically arranged outer cylinder 101 with both ends closed, a primary stage tank 102 arranged inside the outer cylinder 101, a liquid storage tank 103, a negative pressure pipe group, a liquid inlet pipe group, and a control unit for controlling the on / off of the negative pressure pipe group and the liquid inlet pipe group. Both the primary stage tank 102 and the liquid storage tank 103 are vertically arranged tanks with both ends closed. The primary stage tank 102 and the liquid storage tank 103 are both fixedly connected to the inner wall of the outer cylinder 101. The inner cavity of the primary stage tank 102 can accommodate 3 - 5 milliliters of liquid, and the inner cavity of the liquid storage tank 103 can accommodate 20 - 30 milliliters of liquid. The outer cylinder 101, the primary stage tank 102, and the liquid storage tank 103 are all made of transparent materials, preferably made of acrylic. A scale line is provided on the side wall of the liquid storage tank 103 to facilitate reading the volume of the liquid in the liquid storage tank 103. A piston three 1031 is hermetically and slidably connected inside the liquid storage tank 103. The negative pressure mechanism 30 is communicated with the upper inner cavity of the primary stage tank 102 and the upper inner cavity of the liquid storage tank 103 through the negative pressure pipe group. The puncture needle 20 is communicated with the lower inner cavity of the primary stage tank 102 and the lower inner cavity of the liquid storage tank 103 through the liquid inlet pipe group. A sampling pipe 1032 is arranged on the liquid storage tank 103. One end of the sampling pipe 1032 is hermetically communicated with the lower inner cavity of the liquid storage tank 103, and the other end of the sampling pipe 1032 extends out of the outer cylinder 101. A cap 1033 that can open or block the sampling pipe 1032 is arranged at the end of the sampling pipe 1032 that extends out of the outer cylinder 101. Specifically, the cap 1033 is threadedly and hermetically connected to the pipe orifice of the sampling pipe 1032.

[0028] As Figure 1 shown in the figure, the negative pressure mechanism 30 includes a cylinder 301 with one end closed. The cylinder 301 is detachably connected to the upper end face of the outer cylinder 101. Specifically, the cylinder 301 is snap - connected to the upper end face of the outer cylinder 101. A slot is arranged on the upper end face of the outer cylinder 101, and a clamping plate is arranged on the cylinder 301 to be engaged with the slot to achieve the snap - connection. This snap - connection method is a conventional technology and will not be elaborated. A piston two 302 is hermetically and slidably connected inside the cylinder 301. A push rod two 303 is arranged on the piston two 302 along the axis of the cylinder 301. One end of the push rod two 303 is fixedly connected to the piston two 302, and the other end of the push rod two 303 extends out of the cylinder 301 from the closed end of the cylinder 301. The push rod two 303 is hermetically and slidably connected to the closed end of the cylinder 301. An insertion hole is arranged on the side wall near the closed end of the cylinder 301 to communicate the inner cavity of the closed end of the cylinder 301 with the external space of the cylinder 301.

[0029] As Figures 1-3As shown, the control unit includes a riser 41 with open ends vertically arranged, a sliding column 42 arranged inside the riser 41 and sealingly and slidably connected to the riser 41, a first piston 1021 arranged inside the initial stage tank 102 and sealingly and slidably connected to the initial stage tank 102, a first push rod 1022 with its lower end fixedly connected to the first piston 1021 and its upper end vertically extending out of the initial stage tank 102, a stop rod 421 horizontally arranged with one end fixedly connected to the sliding column 42 and the other end extending out of the riser 41, a vertical groove 411 corresponding to the stop rod 421 and opened on the side wall of the riser 41 to allow the stop rod 421 to slide along the axial direction of the riser 41, an upper through hole 422 horizontally penetrating the upper end of the sliding column 42 along the radial direction of the sliding column 42, a lower through hole 423 horizontally penetrating the lower end of the sliding column 42 along the radial direction of the sliding column 42, a cavity 424 arranged inside the lower end of the sliding column 42, an upper through hole 425 arranged on the side wall of the cavity 424 to connect the upper inner cavity of the cavity 424 with the external space of the sliding column 42, a lower through hole 426 arranged on the side wall of the cavity 424 to connect the lower inner cavity of the cavity 424 with the external space of the sliding column 42, and a first spring 43 arranged at the upper end of the sliding column 42. An upper air hole 1011 is opened on the top plate of the outer cylinder 101 corresponding to the inner cavity of the riser 41 to connect the upper inner cavity of the riser 41 with the external space of the outer cylinder 101, and a lower air hole 1012 is opened on the bottom plate of the outer cylinder 101 corresponding to the inner cavity of the riser 41 to connect the lower inner cavity of the riser 41 with the external space of the outer cylinder 101. A one-way valve 1013 that only allows air flow to enter the lower inner cavity of the riser 41 is arranged at the lower air hole 1012.

[0030] In the above solution, the first push rod 1022 is sealingly and slidably connected to the top plate of the initial stage tank 102. The upper end of the first spring 43 is fixedly connected to the top plate of the outer cylinder 101, and the lower end of the first spring 43 is fixedly connected to the upper end surface of the sliding column 42. The upper end of the riser 41 is fixedly connected to the top plate of the outer cylinder 101, and the lower end of the riser 41 is sealingly and fixedly connected to the bottom plate of the outer cylinder 101. The first push rod 1022 is sealingly and slidably connected to the top plate of the initial stage tank 102. The axis of the stop rod 421 and the axis of the first push rod 1022 are arranged in the same plane. The stop rod 421 can only slide up and down in the vertical groove 411, so that the sliding column 42 can only slide up and down and cannot rotate around its own axis. The cavity 424 is arranged above the lower through hole 423.

[0031] The negative pressure tube group includes a first negative pressure tube 51, a transverse negative pressure tube 1 52 and a transverse negative pressure tube 2 53 coaxially arranged with the transverse negative pressure tube 1 52. The first negative pressure tube 51 connects the upper inner cavity of the initial stage tank 102 with the negative pressure mechanism 30, one end of the transverse negative pressure tube 1 52 is sealedly connected to the inner cavity of the first negative pressure tube 51, and the other end of the transverse negative pressure tube 1 52 is also sealedly connected to the upper inner cavity of the stand pipe 41, one end of the transverse negative pressure tube 2 53 is sealedly connected to the upper inner cavity of the stand pipe 41, and the other end of the transverse negative pressure tube 2 53 is also sealedly connected to the upper inner cavity of the liquid storage tank 103, the upper end of the first negative pressure tube 51 extends upward out of the outer tube 101, the lower end of the first negative pressure tube 51 is sealedly connected to the upper inner cavity of the initial stage tank 102, and the upper end of the first negative pressure tube 51 is sealedly plugged into the socket.

[0032] The liquid inlet tube group includes a liquid inlet tube 1 61 whose one end is connected to the puncture needle 20 and whose other end is sealedly connected to the lower inner cavity of the stand pipe 41, a liquid inlet tube 2 62 whose one end is sealedly connected to the lower inner cavity of the stand pipe 41 and whose other end is sealedly connected to the lower inner cavity of the initial tank 102, a liquid inlet bypass tube 64 located above the liquid inlet tube 1 61 and whose one end is sealedly connected to the middle inner cavity of the liquid inlet tube 1 61 and whose other end is sealedly connected to the inner cavity of the stand pipe 41, and a liquid inlet bypass tube 64 located above the liquid inlet bypass tube 64 and whose one end is sealedly connected to the inner cavity of the stand pipe 41. The other end of the liquid inlet pipe 63 is sealed and connected to the lower inner cavity of the liquid storage tank 103, and an air intake bypass pipe 70 is arranged below the liquid inlet pipe 2 62. One end of the air intake bypass pipe 70 is sealed and connected to the middle inner cavity of the liquid inlet pipe 2 62, and the other end of the air intake bypass pipe 70 is sealed and connected to the lower inner cavity of the stand pipe 41. An external thread is arranged on the end of the liquid inlet pipe 1 61 connected to the puncture needle 20, and an internal thread is arranged on the outlet end of the puncture needle 20. The puncture needle 20 is threaded and sealedly connected to the liquid inlet pipe 1 61.

[0033] When the present invention is used, Figures 1-3 As shown, under the elastic force of the first spring 43, the lower end of the sliding column 42 contacts the bottom plate of the outer cylinder 101 so that the sliding column 42 blocks the air intake bypass pipe 70 and makes the liquid inlet pipe 1 61, the liquid inlet pipe 2 62 and the lower through hole 423 conductive, and at the same time makes the upper through hole 425 staggered with the liquid inlet pipe 3 63, the lower through hole 426 staggered with the liquid inlet bypass pipe 64, and the transverse negative pressure pipe 1 52, the transverse negative pressure pipe 2 53 and the upper through hole 422 staggered. At this time, the piston 3 1031 is located at the lower part of the inner cavity of the liquid storage tank 103, the piston 1 1021 is located at the lower part of the inner cavity of the initial stage tank 102, so that the push rod 1 1022 is away from the blocking rod 421, and the cap 1033 blocks the sampling tube 1032.

[0034] Insert the upper end of the first negative pressure tube 51 into the jack in a sealed manner and snap the syringe barrel 301 onto the top of the outer cylinder 101. With the assistance of the ultrasonic probe, correctly puncture the puncture needle 20. After correct puncture, thread the puncture needle 20 and the first liquid inlet tube 61 together in a sealed manner. When starting to extract the amniotic fluid in the fetus, the medical staff holds the outer cylinder 101 with one hand and presses the second push rod 303 with the thumb to slide the second piston 302 towards the open end of the syringe barrel 301, causing a negative pressure to be generated in the inner cavity of the closed end of the syringe barrel 301. The negative pressure causes the first piston 1021 to rise through the first negative pressure tube 51. The initial amniotic fluid in the fetus sequentially passes through the puncture needle 20, the first liquid inlet tube 61, the lower through hole 423, and the second liquid inlet tube 62 and enters the lower inner cavity of the initial stage tank 102. When the first piston 1021 rises to contact the top plate of the initial stage tank 102, the amount of amniotic fluid in the initial stage tank 102 is 2 - 3 milliliters. Combining Figure 4 , Figure 5 As shown, when the first piston 1021 rises to a certain height, the first push rod 1022 that moves with the first piston 1021 starts to push the stop rod 421, causing the sliding column 42 to gradually slide upward. External gas enters the inner cavity of the vertical pipe 41 below the sliding column 42 through the lower air hole 1012, and the gas above the sliding column 42 is discharged outside the outer cylinder 101 through the upper air hole 1011. When the sliding column 42 slides upward under the push of the first push rod 1022 to completely stagger the lower through hole 423, the first liquid inlet tube 61, and the second liquid inlet tube 62, the lower end of the sliding column 42 crosses the end port of the intake side pipe 70 communicating with the inner cavity of the vertical pipe 41. Gas enters the initial stage tank 102 through the intake side pipe 70, enabling the first piston 1021 to continue moving upward under negative pressure to continue pushing the sliding column 42 upward and ultimately connecting the upper through hole 425 with the third liquid inlet tube 63, connecting the lower through hole 426 with the liquid inlet side pipe 64, and connecting the first horizontal negative pressure tube 52, the second horizontal negative pressure tube 53, and the upper through hole 422. At this time, the negative pressure generated by the syringe barrel 301 starts to act on the upper inner cavity of the liquid storage tank 103, causing the third piston 1031 to slide upward. Subsequently, the posterior amniotic fluid sequentially passes through the puncture needle 20, the first liquid inlet tube 61, the liquid inlet side pipe 64, the lower through hole 426, the cavity 424, the upper through hole 425, and the third liquid inlet tube 63 and enters the lower inner cavity of the liquid storage tank 103. At this time, since the first push rod 1022 is in contact with the stop rod 421 and the one-way valve 1013 does not allow gas to flow out of the lower inner cavity of the vertical pipe 41, the first spring 43 cannot cause the sliding column 42 to slide downward at this time, and the initial amniotic fluid in the initial stage tank 102 cannot flow outwards. When the medical staff observes that the amount of amniotic fluid entering the liquid storage tank 103 reaches the required amount, stop pressing the second push rod 303 and keep the second push rod 303 stationary. Withdraw the puncture needle 20 from the patient and separate the puncture needle 20 from the first liquid inlet tube 61. Invert the outer cylinder 101 so that the second piston 302 is below the amniotic fluid in the liquid storage tank 103, and then separate the syringe barrel 301 from the outer cylinder 101. Open the cap 1033 to extract the amniotic fluid in the liquid storage tank 103 for cultivation and testing.

[0035] Compared with the existing method of amniotic fluid sampling using a syringe, which requires at least two people to cooperate, the present solution has the beneficial effects of simple operation, allowing a single person to complete amniotic fluid sampling, separating the initial amniotic fluid from the subsequent amniotic fluid without the need for others to help replace the syringe during the entire amniotic fluid sampling process, and saving syringes.

[0036] The above are only embodiments of the present invention. Common knowledge such as specific structures and characteristics well-known in the art are not described in detail herein. It should be noted that for those skilled in the art, without departing from the structure of the present invention, several modifications and improvements can be made, which should also be regarded as the protection scope of the present invention, and these will not affect the implementation effect of the present invention and the practicality of the patent. The protection scope required by this application shall be subject to the content of its claims, and the specific implementation manners described in the specification can be used to interpret the content of the claims.

Claims

1. An obstetric amniotic fluid sampling device, comprising a device body, a puncture needle and a negative pressure mechanism, characterized in that: The device body includes a vertically arranged outer cylinder with closed ends at both ends, a primary tank, a liquid storage tank, a negative pressure pipe group, a liquid inlet pipe group, and a control unit for controlling the on-off of the negative pressure pipe group and the liquid inlet pipe group, which are arranged inside the outer cylinder. The primary tank and the liquid storage tank are both vertically arranged tanks with closed ends at both ends. The negative pressure mechanism is communicated with the upper inner cavity of the primary tank and the upper inner cavity of the liquid storage tank through the negative pressure pipe group. The puncture needle is communicated with the lower inner cavity of the primary tank and the lower inner cavity of the liquid storage tank through the liquid inlet pipe group. A sampling pipe is arranged on the liquid storage tank. One end of the sampling pipe is hermetically communicated with the lower inner cavity of the liquid storage tank, and the other end of the sampling pipe extends outside the outer cylinder. A cap for opening or blocking the sampling pipe is arranged at the end of the sampling pipe extending outside the outer cylinder; The control unit includes a vertically arranged riser with open ends at both ends, a sliding column arranged inside the riser and hermetically slidingly connected with the riser, a first piston arranged inside the primary tank and hermetically slidingly connected with the primary tank, a first push rod with its lower end fixedly connected to the first piston and its upper end vertically extending out of the primary tank, a stop rod horizontally arranged with one end fixedly connected to the sliding column and the other end extending out of the riser, a vertical groove opened on the side wall of the riser corresponding to the stop rod for allowing the stop rod to slide along the axial direction of the riser, an upper through hole horizontally penetrating the upper end of the sliding column in the radial direction of the sliding column, a lower through hole horizontally penetrating the lower end of the sliding column in the radial direction of the sliding column, a cavity arranged inside the lower end of the sliding column, an upper through hole arranged on the side wall of the cavity for communicating the upper inner cavity of the cavity with the external space of the sliding column, a lower through hole arranged on the side wall of the cavity for communicating the lower inner cavity of the cavity with the external space of the sliding column, and a first spring arranged at the upper end of the sliding column. The upper end of the riser is fixedly connected to the top plate of the outer cylinder, and the lower end of the riser is hermetically and fixedly connected to the bottom plate of the outer cylinder; The negative pressure pipe group includes a first negative pressure pipe, a first horizontal negative pressure pipe, and a second horizontal negative pressure pipe coaxially arranged with the first horizontal negative pressure pipe. The first negative pressure pipe communicates the upper inner cavity of the primary tank with the negative pressure mechanism. One end of the first horizontal negative pressure pipe is hermetically communicated with the inner cavity of the first negative pressure pipe, and the other end of the first horizontal negative pressure pipe is hermetically communicated with the upper inner cavity of the riser. One end of the second horizontal negative pressure pipe is hermetically communicated with the upper inner cavity of the riser, and the other end of the second horizontal negative pressure pipe is hermetically communicated with the upper inner cavity of the liquid storage tank; The liquid inlet pipe group includes a first liquid inlet pipe with one end communicated with the puncture needle and the other end hermetically communicated with the lower inner cavity of the riser, a second liquid inlet pipe with one end hermetically communicated with the lower inner cavity of the riser and the other end hermetically communicated with the lower inner cavity of the primary tank, a liquid inlet bypass pipe located above the first liquid inlet pipe with one end hermetically communicated with the middle inner cavity of the first liquid inlet pipe and the other end hermetically communicated with the inner cavity of the riser, and a third liquid inlet pipe located above the liquid inlet bypass pipe with one end hermetically communicated with the inner cavity of the riser and the other end hermetically communicated with the lower inner cavity of the liquid storage tank; When the negative pressure mechanism operates to generate negative pressure, the negative pressure mechanism first generates negative pressure in the upper inner cavity of the initial stage tank through the first negative pressure pipe, so that the initial stage amniotic fluid first enters the lower inner cavity of the initial stage tank through the liquid inlet pipe one and then through the liquid inlet pipe two, and makes the piston one drive the push rod one to move upward, and pushes the sliding column to slide upward through the blocking rod. When the lower inner cavity of the initial stage tank is filled with the initial stage amniotic fluid, the push rod one pushes the sliding column to slide upward until the negative pressure mechanism is communicated with the upper inner cavity of the liquid storage tank and the lower inner cavity of the liquid storage tank is communicated with the liquid inlet pipe one. The negative pressure mechanism generates negative pressure in the upper inner cavity of the liquid storage tank, so that the subsequent amniotic fluid enters the lower inner cavity of the liquid storage tank.

2. The obstetric amniotic fluid sampling device according to claim 1, characterized in that: The lower end of the first spring is fixedly connected to the upper end surface of the sliding column. An upper air hole for communicating the upper inner cavity of the riser pipe with the external space of the outer cylinder is opened on the top plate of the outer cylinder corresponding to the inner cavity of the riser pipe, and a lower air hole for communicating the lower inner cavity of the riser pipe with the external space of the outer cylinder is opened on the bottom plate of the outer cylinder corresponding to the inner cavity of the riser pipe. A one-way valve one that only allows air flow to enter the lower inner cavity of the riser pipe is arranged at the lower air hole.

3. The obstetric amniotic fluid sampling device according to claim 2, wherein: The negative pressure mechanism includes a cylinder with one end closed. A piston two is hermetically and slidably connected in the cylinder. A push rod two is arranged on the piston two along the axis of the cylinder. One end of the push rod two is fixedly connected to the piston two, and the other end of the push rod two extends out of the cylinder from the closed end of the cylinder. The push rod two is hermetically and slidably connected to the closed end of the cylinder. The end of the first negative pressure pipe far from the initial stage tank is communicated with the inner cavity of the closed end of the cylinder.

4. The obstetric amniotic fluid sampling device according to claim 3, wherein: An air inlet bypass pipe is arranged below the liquid inlet pipe two. One end of the air inlet bypass pipe is hermetically communicated with the middle inner cavity of the liquid inlet pipe two, and the other end of the air inlet bypass pipe is hermetically communicated with the lower inner cavity of the riser pipe.

5. The obstetric amniotic fluid sampling device according to claim 4, wherein: The end of the liquid inlet pipe one connected to the puncture needle is provided with an external thread, and the outlet end of the puncture needle is provided with an internal thread. The puncture needle is threadedly connected to the liquid inlet pipe one.

6. The obstetric amniotic fluid sampling device according to claim 5, wherein: The cylinder is detachably connected to the outer cylinder. The upper end of the first negative pressure pipe extends upward out of the outer cylinder. The lower end of the first negative pressure pipe is hermetically communicated with the upper inner cavity of the initial stage tank. A jack for communicating the inner cavity of the closed end of the cylinder with the external space of the cylinder is arranged on the side wall near the closed end of the cylinder. The upper end of the first negative pressure pipe is hermetically inserted into the jack.

7. The obstetric amniotic fluid sampling device according to claim 6, characterized in that: The outer cylinder, the initial stage tank and the liquid storage tank are all made of transparent materials.

8. The obstetric amniotic fluid sampling device according to claim 7, wherein: Scale lines are provided on the side wall of the liquid storage tank, and a piston three is hermetically and slidably connected in the liquid storage tank.

9. The obstetric amniotic fluid sampling device according to claim 7, wherein: The cylinder is clamped to the outer cylinder.

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