A skin healing oil containing ginseng and astragalus, and a preparation method and application thereof

Abstract

The application discloses a ginseng and astragalus root skin healing oil and a preparation method and application thereof, and belongs to the technical field of traditional Chinese medicine. The ginseng and astragalus root skin healing oil and the preparation method and application thereof are provided in the application in the light of the problems of a complicated formula of an existing skin healing oil and a treatment effect to be improved, and are composed of the following raw materials in parts by weight: angelica 180-220 parts, ginseng 130-170 parts, frankincense 60-100 parts, myrrh 60-100 parts, dragon's blood 60-100 parts, calcined oyster shell 130-170 parts, catechu 60-100 parts, baizhi 60-100 parts, radix lithospermi 60-100 parts, borneol 60-100 parts, raw licorice 100-140 parts, sesame oil 800-1500 parts. The ginseng and astragalus root skin healing oil has the functions of nourishing blood and benefiting qi, promoting blood circulation to remove heat, detoxifying and promoting tissue regeneration, has no stimulation to skin mucosa, can rapidly reduce purulent exudates of a wound surface, can effectively control wound infection, improves the nutritional state of the wound surface, and thus promotes healing.

Description

Technical Field

[0001] This invention belongs to the field of traditional Chinese medicine technology, specifically relating to a ginseng and angelica skin-healing oil, its preparation method, and its application. Background Technology

[0002] Pressure ulcers in ICU patients are caused by qi and blood deficiency due to severe illness. Because these patients are bedridden, local pressure and friction on the body lead to poor blood circulation, malnutrition of the skin, and ultimately, skin necrosis. The core pathogenesis is qi and blood deficiency and poor blood circulation, and long-term qi and blood stagnation often manifests as heat in the affected area. Western medicine treatment for pressure ulcers often uses disinfectants or antibiotics, which can effectively inhibit bacteria and prevent further deterioration, but also affect wound regeneration, resulting in slower healing. Traditional Chinese medicine (TCM) treatment for pressure ulcers has fewer side effects and is safer; therefore, it is necessary to research TCM formulas for treating pressure ulcers and other pressure injuries.

[0003] The invention patent with patent number CN 102836414 B discloses a topical Chinese medicine oil for treating shingles, burns, and bedsores. It has the effects of promoting blood circulation, removing blood stasis, astringing and promoting tissue regeneration, and reducing inflammation and relieving pain. However, its formula is complex and the therapeutic effect needs to be improved. Summary of the Invention

[0004] In view of the problem that the traditional Chinese medicine formulas of the topical Chinese medicine oils used to treat bedsores are complex and the therapeutic effect needs to be improved, the present invention provides a ginseng and angelica skin-healing oil, its preparation method and application.

[0005] The technical solution adopted in this invention is as follows:

[0006] A ginseng and angelica skin-healing oil is composed of the following raw materials in parts by weight: 180-220 parts of angelica, 130-170 parts of ginseng, 60-100 parts of frankincense, 60-100 parts of myrrh, 60-100 parts of dragon's blood, 130-170 parts of calcined dragon bone, 60-100 parts of catechu, 60-100 parts of angelica dahurica, 60-100 parts of gromwell root, 60-100 parts of borneol, 100-140 parts of raw licorice, and 800-1500 parts of sesame oil.

[0007] In this prescription, Angelica sinensis invigorates qi and nourishes blood, promotes blood circulation, relieves pain, removes necrotic tissue, and promotes tissue regeneration; Angelica dahurica reduces swelling and relieves pain, and treats carbuncles and sores; Glycyrrhiza uralensis clears heat and detoxifies, and disperses pain and swelling; Lithospermum erythrorhizon cools blood, invigorates blood circulation, clears heat and detoxifies; Dragon's blood (for external use) astringes and stops bleeding, softens hard masses, disperses nodules, and promotes tissue regeneration; Frankincense invigorates blood and relieves pain; Myrrh has anti-inflammatory and antibacterial properties; Catechu invigorates blood circulation, promotes tissue regeneration, and astringes sores; Borneol is pungent and cool, disperses stagnant heat, reduces swelling and relieves pain, and promotes local absorption; Calcined dragon bone astringes and promotes tissue regeneration. This prescription uses Angelica sinensis and ginseng as the principal herbs to invigorate qi and nourish blood, and invigorate blood circulation. Frankincense, Myrrh, and Angelica dahurica are used as assistant herbs to invigorate blood circulation, promote tissue regeneration, and drain pus. Dragon's blood, calcined dragon bone, and Catechu are used as adjuvant herbs to remove necrotic tissue, astringe sores, and promote tissue regeneration. Lithospermum erythrorhizon and Borneol clear heat and detoxify. Glycyrrhiza uralensis and sesame oil are used as guiding herbs to invigorate qi, detoxify, moisturize the skin, and harmonize the effects of all the herbs. When used together, these herbs work synergistically to nourish blood and qi, invigorate blood and clear heat, detoxify and promote tissue regeneration. They are also non-irritating to the skin and mucous membranes, can rapidly reduce purulent discharge from wounds, effectively control wound infection, improve the nutritional status of the wound, and thus promote healing.

[0008] As a preferred choice, the ingredients are: 200g Angelica sinensis, 150g ginseng, 80g frankincense, 80g myrrh, 80g dragon's blood, 150g calcined dragon bone, 80g catechu, 80g Angelica dahurica, 80g Lithospermum erythrorhizon, 80g borneol, 120g raw licorice, and 1000ml sesame oil.

[0009] A method for preparing a ginseng and angelica skin-healing oil includes the following steps:

[0010] Step A: Add 180-220 parts of Angelica sinensis, 130-170 parts of ginseng, 60-100 parts of frankincense, 60-100 parts of myrrh, 60-100 parts of dragon's blood, 130-170 parts of calcined dragon bone, 60-100 parts of catechu, 60-100 parts of Angelica dahurica, and 100-140 parts of raw licorice to 800-1500 parts of sesame oil, mix well, and then proceed with the first boiling.

[0011] Step B: After the first decoction, remove the dregs and immediately add 60-100 parts of purple gromwell root for the second decoction;

[0012] Step C: After the second decoction is completed, remove the dregs and add 60-100 parts of borneol after the liquid has cooled. After the borneol melts, you will get Ginseng and Angelica Skin Healing Oil. Refrigerate the Ginseng and Angelica Skin Healing Oil for later use.

[0013] Preferably, the oil temperature for the first boiling in step A is 100-150℃, and the boiling time is 80-120 minutes.

[0014] Preferably, the second cooking time in step B is 5-20 minutes.

[0015] Preferably, the refrigeration temperature in step C is 2-8°C.

[0016] The application of the above-mentioned ginseng and angelica skin-healing oil or the ginseng and angelica skin-healing oil prepared by the above-mentioned preparation method in the treatment of bedsores, pressure injuries, arteriovenous ulcers, burns, incontinence dermatitis and edema.

[0017] After adopting this technical solution, this formula treats the root cause of pressure injury by invigorating qi and nourishing blood, while focusing on promoting blood circulation and removing blood stasis, and adding a small amount of heat-clearing, detoxifying, and wound-healing herbs to treat the symptoms.

[0018] In summary, due to the adoption of the above technical solution, the beneficial effects of the present invention are:

[0019] 1. In this prescription, Angelica sinensis invigorates qi and nourishes blood, promotes blood circulation, relieves pain, removes necrotic tissue, and promotes tissue regeneration; Angelica dahurica reduces swelling and relieves pain, and treats carbuncles and sores; Glycyrrhiza uralensis clears heat and detoxifies, and disperses pain and swelling; Lithospermum erythrorhizon cools blood, invigorates blood circulation, clears heat and detoxifies; Dragon's blood (for external use) astringes and stops bleeding, softens hard masses, disperses nodules, and promotes tissue regeneration; Frankincense invigorates blood and relieves pain; Myrrh has anti-inflammatory and antibacterial properties; Catechu invigorates blood circulation, promotes tissue regeneration, and astringes sores; Borneol is pungent and cool, disperses stagnant heat, reduces swelling and relieves pain, and promotes local absorption; Calcined dragon bone astringes and promotes tissue regeneration. This prescription uses Angelica sinensis and ginseng as the chief ingredients to invigorate qi and nourish blood, and invigorate blood circulation. Frankincense, Myrrh, and Angelica dahurica are used as assistant ingredients to invigorate blood circulation, promote tissue regeneration, and drain pus. Dragon's blood, calcined dragon bone, and Catechu are used as adjuvant ingredients to remove necrotic tissue, astringe sores, and promote tissue regeneration. Lithospermum erythrorhizon and Borneol clear heat and detoxify. Glycyrrhiza uralensis and sesame oil are used as guiding ingredients to invigorate qi, detoxify, moisturize the skin, and harmonize all the ingredients.

[0020] 2. When used together, these herbs nourish blood and qi, invigorate blood and clear heat, detoxify and promote tissue regeneration. They are non-irritating to the skin and mucous membranes, can quickly reduce purulent discharge from wounds, effectively control wound infection, improve the nutritional status of wounds, and thus promote healing.

[0021] 3. This formula addresses the root cause of stress injury by invigorating qi and nourishing blood, while focusing on promoting blood circulation and removing blood stasis. It also includes a small amount of heat-clearing, detoxifying, and wound-healing herbs to treat the symptoms. Detailed Implementation

[0022] To make the objectives, technical solutions, and advantages of the embodiments of this application clearer, the technical solutions in the embodiments of this application will be clearly and completely described below. Obviously, the described embodiments are only some embodiments of this application, and not all embodiments.

[0023] Example 1

[0024] A ginseng and angelica skin-healing oil is composed of the following ingredients: 200g angelica sinensis, 150g ginseng, 80g frankincense, 80g myrrh, 80g dragon's blood, 150g calcined dragon bone, 80g catechu, 80g angelica dahurica, 80g gromwell root, 80g borneol, 120g raw licorice root, and 1000ml sesame oil. The preparation method of this ginseng and angelica skin-healing oil includes the following steps:

[0025] Step A: Add 200g of Angelica sinensis, 150g of ginseng, 80g of frankincense, 80g of myrrh, 80g of dragon's blood, 150g of calcined dragon bone, 80g of catechu, 80g of Angelica dahurica, and 120g of raw licorice to 1000ml of sesame oil and mix well. Then, make the first decoction at 120 degrees Celsius for 90 minutes.

[0026] Step B: After the first decoction, remove the dregs, then add 80g of purple gromwell root for a second decoction at 120 degrees Celsius for 10 minutes.

[0027] Step C: After the second decoction, remove the dregs, then add 80g of borneol. After the borneol melts, you will get Ginseng and Angelica Skin Healing Oil. Refrigerate the Ginseng and Angelica Skin Healing Oil at 4℃ for later use.

[0028] Example 2

[0029] A ginseng and angelica skin-healing oil is composed of the following ingredients: 180g angelica sinensis, 120g ginseng, 60g frankincense, 60g myrrh, 60g dragon's blood, 130g calcined dragon bone, 60g catechu, 60g angelica dahurica, 60g gromwell root, 60g borneol, 100g raw licorice root, and 800ml sesame oil. The preparation method of this ginseng and angelica skin-healing oil includes the following steps:

[0030] Step A: Add 180g of Angelica sinensis, 120g of ginseng, 60g of frankincense, 60g of myrrh, 60g of dragon's blood, 130g of calcined dragon bone, 60g of catechu, 60g of Angelica dahurica, and 100g of raw licorice to 800ml of sesame oil and mix well. Then, make the first decoction at 150 degrees Celsius for 80 minutes.

[0031] Step B: After the first decoction, remove the dregs, then add 60g of purple gromwell root for a second decoction at 150 degrees Celsius for 8 minutes.

[0032] Step C: After the second decoction, remove the dregs, then add 60g of borneol. After the borneol melts, you will get Ginseng and Angelica Skin Healing Oil. Refrigerate the Ginseng and Angelica Skin Healing Oil at 6℃ for later use.

[0033] Example 3

[0034] A ginseng and angelica skin-healing oil is composed of the following ingredients: 220g angelica sinensis, 170g ginseng, 100g frankincense, 100g myrrh, 100g dragon's blood, 170g calcined dragon bone, 100g catechu, 100g angelica dahurica, 100g gromwell root, 100g borneol, 140g raw licorice root, and 1500ml sesame oil. The preparation method of this ginseng and angelica skin-healing oil includes the following steps:

[0035] Step A: Add 220g of Angelica sinensis, 170g of ginseng, 100g of frankincense, 100g of myrrh, 100g of dragon's blood, 170g of calcined dragon bone, 100g of catechu, 100g of angelica dahurica, and 140g of raw licorice to 1500ml of sesame oil and mix well. Then, make the first decoction at 100 degrees Celsius for 120 minutes.

[0036] Step B: After the first decoction, remove the dregs, then add 100g of purple gromwell root for a second decoction. The decoction temperature is 100 degrees Celsius and the decoction time is 15 minutes.

[0037] Step C: After the second decoction, remove the dregs, then add 100g of borneol. After the borneol melts, you will get Ginseng and Angelica Skin Healing Oil. Refrigerate the Ginseng and Angelica Skin Healing Oil at 2°C for later use.

[0038] (I) The application of the ginseng and angelica skin-healing oil prepared in Example 1 in the treatment of pressure injuries is as follows:

[0039] The clinical application method is as follows: apply wet dressing with gauze as a medium, or apply directly to superficial wounds, and change the dressing 1-2 times a day.

[0040] Case selection criteria:

[0041] Table 1 Comparison of general conditions of patients in the two groups before treatment.

[0042]

[0043] The following are typical cases of using this ginseng and angelica skin-healing oil to treat pressure injuries:

[0044] Case 1

[0045] Mr. Su, male, 48 years old, was diagnosed with pneumonia and wheezing, and stroke according to Traditional Chinese Medicine; and with severe pneumonia, septic shock, and acute respiratory distress syndrome according to Western medicine. He was of average development, malnourished, and his nutritional risk screening score (NRS2002) was moderate. He suffered a stage 4 pressure injury to the sacrococcygeal region. After cleaning and disinfecting with povidone-iodine and saline solution to remove necrotic tissue and secretions, the wound was treated with the oil-soaked gauze of this invention, followed by a sterile gauze dressing to reduce pressure. The dressing was changed once a day for 10 consecutive days, after which the wound shrank and eventually healed.

[0046] Case 2

[0047] Mr. Xing, male, 92 years old, was diagnosed with pulmonary failure (lung and kidney deficiency syndrome) by Traditional Chinese Medicine; and with chronic obstructive pulmonary disease (respiratory failure), multiple cerebral infarctions, and chronic renal failure (CKD5, renal anemia) by Western medicine, with a severe score on the Nutritional Risk Screening Scale (NRS2002). He had a stage 3 pressure injury to his left hip. After cleaning and disinfecting with povidone-iodine and saline solution to remove necrotic tissue and secretions, the wound was treated with the oil-soaked gauze of this invention, followed by a sterile gauze dressing to reduce pressure. The dressing was changed once a day for 10 consecutive days, after which the wound shrank and eventually healed.

[0048] Case 3

[0049] Ms. Ning, 86 years old, was diagnosed with pneumonia and wheezing (lung and spleen qi deficiency syndrome) by Traditional Chinese Medicine; and with type II respiratory failure (post-tracheotomy), secondary epilepsy (Parkinson's disease), and atrial fibrillation by Western Medicine; she was also malnourished, with a severe nutritional risk screening score (NRS2002). She had a stage II pressure injury on her left upper arm. After cleaning and disinfecting with povidone-iodine and saline solution to remove necrotic tissue and secretions, the wound was treated with the oil-soaked gauze of this invention, then covered with sterile gauze to reduce pressure. The dressing was changed once a day, and after two consecutive days of treatment, the wound shrank and eventually healed.

[0050] Case 4

[0051] Mr. Lu, male, 89 years old, was diagnosed with stroke (phlegm and blood stasis syndrome) by Traditional Chinese Medicine and severe pneumonia (type I respiratory failure), basal ganglia hemorrhage, and pleural effusion by Western medicine. He was well-nourished, with a moderate nutritional risk assessment score on the National Nutritional Risk Screening System (NRS2002). He suffered a stage II pressure injury to the sacrococcygeal region. After cleaning and disinfecting with povidone-iodine and saline solution to remove necrotic tissue and secretions, the wound was treated with the oil-soaked gauze of this invention, followed by a sterile gauze dressing to reduce pressure. The dressing was changed once a day for two consecutive days, after which the wound shrank and eventually healed.

[0052] Case 5

[0053] Mr. Liao, male, 88 years old, was diagnosed with renal failure (spleen and kidney deficiency syndrome) by Traditional Chinese Medicine; and with chronic renal failure (CKD stage 5), severe pneumonia, and chronic heart failure (NYHA Class III) by Western medicine. He was malnourished, with a severe nutritional risk screening score (NRS2002). He suffered a stage 2 pressure injury to the sacrococcygeal region. After cleaning and disinfecting with povidone-iodine and saline solution to remove necrotic tissue and secretions, the wound was treated with the oil-soaked gauze of this invention, followed by a sterile gauze dressing to reduce pressure. The dressing was changed once a day for 7 consecutive days, after which the wound shrank and eventually healed.

[0054] Case 6

[0055] Ms. Zhu, 90 years old, was diagnosed with heart-water disease (cardiopulmonary qi deficiency syndrome) by Traditional Chinese Medicine; and with hypoglycemia, type 2 diabetes, and persistent atrial fibrillation by Western Medicine. She was of normal development and well-nourished, with a moderate nutritional risk assessment score (NRS2002). She suffered a stage 2 pressure injury to the sacrococcygeal region. After cleaning and disinfecting with povidone-iodine and saline solution to remove necrotic tissue and secretions, the wound was treated with the oil-soaked gauze of this invention, followed by a sterile gauze dressing to reduce pressure. The dressing was changed once a day for 7 consecutive days, after which the wound shrank and eventually healed.

[0056] Case 7

[0057] Ms. Yi, 77 years old, was diagnosed with pulmonary failure (spleen deficiency and phlegm dampness syndrome) by Traditional Chinese Medicine; and with central respiratory failure (difficulty in extubation after tracheotomy), sequelae of hypoxic-ischemic encephalopathy (secondary epilepsy), and sequelae of cerebral infarction by Western medicine. She was well-nourished, with a moderate nutritional risk score on the National Nutritional Risk Screening System (NRS2002). She suffered a stage II pressure injury to her left upper arm and axilla. After cleaning and disinfecting with povidone-iodine and saline solution to remove necrotic tissue and secretions, the wound was treated with the oil-soaked gauze of this invention, followed by a sterile gauze dressing to reduce pressure. The dressing was changed once a day for three consecutive days, after which the wound shrank and eventually healed.

[0058] Case 8

[0059] Mr. Ji, male, 89 years old, was diagnosed with pneumonia and cough (phlegm-heat stagnation syndrome) and stroke (qi deficiency and blood stasis syndrome) by Traditional Chinese Medicine; and with Klebsiella pneumoniae pneumonia, recovery period of left basal ganglia hemorrhage, and multiple cerebral infarctions by Western medicine. He was of normal development and well-nourished, with a moderate nutritional risk assessment score (NRS2002). He suffered a stage 4 pressure injury to the sacrococcygeal region. After cleaning and disinfecting with povidone-iodine and saline solution to remove necrotic tissue and secretions, the wound was treated with the oil-soaked gauze of this invention, followed by a sterile gauze dressing to reduce pressure. The dressing was changed once a day for 10 consecutive days, after which the wound shrank and eventually healed.

[0060] Case 9

[0061] Ms. Ze, 33 years old, was diagnosed with collapse syndrome (exhaustion of Yang Qi) in Traditional Chinese Medicine; and with severe traumatic shock ARDS, complicated abdominal infection, and a penetrating abdominal wound with extensive abdominal wall skin rupture (exposed intestines, ruptured stomach / duodenum) in Western medicine. She was of normal development, moderately nutritious, and her Nutritional Risk Screening Score (NRS2002) was moderate. The chest and abdominal wounds were cleaned and disinfected with povidone-iodine and saline solution to remove necrotic tissue and secretions. The wound was then treated with the oil-soaked gauze of this invention, followed by a sterile gauze dressing to reduce pressure. The dressing was changed twice daily for 14 consecutive days, after which the wound shrank and eventually healed.

[0062] Efficacy assessment method: Wound healing was assessed by wound and stoma specialist nurses at patient enrollment, 7 days, 14 days, and 21 days. The length and width of the wound were measured using specialized calipers, and the wound area was calculated. The wound healing rate was calculated based on the wound area [Wound healing rate = (Wound area before intervention - Wound area after xx days of intervention) / Wound area before intervention * 100%].

[0063] Efficacy evaluation criteria: Cure: The wound is completely covered with new epithelium, and there are no false healing phenomena such as subcutaneous pus accumulation;

[0064] Significant effect: Wound healing area >75%, fresh granulation tissue;

[0065] Improvement: 25% < wound healing area ≤ 75%, with a small amount of granulation tissue visible;

[0066] Ineffective: Wound healing area ≤25%, no granulation tissue.

[0067]

[0068] Efficacy analysis: The comparison of cytokine levels in the wound tissues of the two groups is shown in Table 2. The control group received routine treatment, including cleaning the wound with 0.9% sterile saline. If there was a lot of necrotic tissue, it could be removed with forceps or scissors. If infection occurred, it was disinfected with povidone-iodine. Depending on the size of the wound, it was covered with a Vaseline gauze pad, then a sterile gauze pad, and finally wrapped with a medical cotton pad and properly secured. The dressing was changed once a day. The comparison of wound healing between the two groups is shown in Table 3. The comparison of the overall clinical efficacy between the two groups is shown in Table 4.

[0069] Table 2

[0070]

[0071]

[0072] Note: *P<0.05, **P<0.01 compared with pre-treatment values; compared with the control group, # P < 0.05 ## P < 0.01;

[0073] As can be seen from Table 2, the reduction in IL-Iβ, IL-6 and TNF-α after using the Ginseng and Angelica Skin Oil of Example 1 was significantly greater than that in the blank control group.

[0074] Table 3

[0075]

[0076] Note: *P<0.05, **P<0.01 compared with pre-treatment values; compared with the control group, # P < 0.05## P < 0.01;

[0077] As can be seen from Table 3, the wound area was reduced more significantly after using the Ginseng and Angelica Healing Oil of Example 1 compared to the blank control group, and the wound healing rate was more than twice that of the blank control group.

[0078] Table 4

[0079]

[0080] As can be seen from Table 4, the total effective rate of the Ginseng and Angelica Skin Oil of Example 1 was much higher than that of the blank control group, and it was effective for all patients and could be used to treat pressure injuries.

[0081] The above embodiments demonstrate that the ginseng and angelica skin-healing oil of the present invention can effectively treat stress injuries with significant results.

[0082] The embodiments described above merely illustrate specific implementation methods of this application, and while the descriptions are detailed and specific, they should not be construed as limiting the scope of protection of this application. It should be noted that those skilled in the art can make various modifications and improvements without departing from the concept of the technical solution of this application, and these modifications and improvements all fall within the scope of protection of this application.

Claims

1. A ginseng and angelica skin-healing oil, characterized in that: The raw materials are: Angelica sinensis 180-220 parts, ginseng 130-170 parts, frankincense 60-100 parts, myrrh 60-100 parts, dragon's blood 60-100 parts, calcined dragon bone 130-170 parts, catechu 60-100 parts, angelica dahurica 60-100 parts, gromwell root 60-100 parts, borneol 60-100 parts, raw licorice root 100-140 parts, and sesame oil 800-1500 parts.

2. The ginseng and angelica skin-healing oil according to claim 1, characterized in that: The ingredients are: 200g Angelica sinensis, 150g ginseng, 80g frankincense, 80g myrrh, 80g dragon's blood, 150g calcined dragon bone, 80g catechu, 80g Angelica dahurica, 80g Lithospermum erythrorhizon, 80g borneol, 120g raw licorice, and 1000ml sesame oil.

3. A method for preparing the ginseng and angelica skin-healing oil as described in claim 1, characterized in that: Includes the following steps: Step A: Add 180-220 parts of Angelica sinensis, 130-170 parts of ginseng, 60-100 parts of frankincense, 60-100 parts of myrrh, 60-100 parts of dragon's blood, 130-170 parts of calcined dragon bone, 60-100 parts of catechu, 60-100 parts of Angelica dahurica, and 100-140 parts of raw licorice to 800-1500 parts of sesame oil, mix well, and then proceed with the first boiling. Step B: After the first decoction, remove the dregs and immediately add 60-100 parts of purple gromwell root for the second decoction; Step C: After the second decoction is completed, remove the dregs and add 60-100 parts of borneol after the liquid has cooled. After the borneol melts, you will get Ginseng and Angelica Skin Healing Oil. Refrigerate the Ginseng and Angelica Skin Healing Oil for later use.

4. The method for preparing a ginseng and angelica skin-healing oil according to claim 3, characterized in that: In step A, the oil temperature for the first boiling is 100-150℃, and the boiling time is 80-120 minutes.

5. The method for preparing a ginseng and angelica skin-healing oil according to claim 3, characterized in that: The second simmering time in step B is 5-20 minutes.

6. The method for preparing a ginseng and angelica skin-healing oil according to claim 3, characterized in that: The refrigeration temperature in step C is 2-8℃.

7. The use of the ginseng and angelica skin-healing oil according to any one of claims 1-2, or the ginseng and angelica skin-healing oil prepared by the preparation method of the ginseng and angelica skin-healing oil according to any one of claims 3-6, in the preparation of a drug for treating pressure injuries.

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