Liquid storage and release device

Abstract

The present invention discloses a liquid storage and release device. The liquid storage and release device includes: a pushing device, a liquid storage device and a chip. The liquid storage device is provided with multiple chambers, the pushing device extends into the liquid storage device, and the bottom of the pushing device is slidably connected to the liquid storage device. One end of the liquid storage device is connected to the buckle above the pushing device, and the other end of the liquid storage device is connected to the chip buckle. When using the liquid storage and release device to release liquid, the liquid storage device is first connected to the chip buckle, and then the buckle above the pushing device is squeezed and the pushing device is pressed downward to release the liquid in the multiple chambers inside the liquid storage device at the same time, thereby achieving the purpose of releasing the liquid to the device to be tested before testing. The liquid storage and release device has a simple structure and is easy to operate, and can release multiple samples to be tested at the same time to achieve the technical effect of testing multiple samples at the same time.

Description

Technical Field

[0001] The present invention relates to the field of liquid storage and release, and in particular to a liquid storage and release device. Background Art

[0002] Before nucleic acid testing, the nucleic acid sample needs to be stored and transferred. After the sample is sent to the testing center, the nucleic acid sample and reaction reagents are released into the testing instrument for nucleic acid testing. However, due to the lack of coordination between the liquid storage device and the testing equipment, when the nucleic acid sample is transferred, the nucleic acid sample is often not well preserved or lost during the transfer process. At the same time, the liquid storage device in the existing technology is expensive, and the process of releasing the liquid is relatively complicated, and it is not possible to release multiple collected samples at the same time.

[0003] Therefore, the liquid storage and release devices in the prior art have technical problems such as high cost, complex operation, and inability to release multiple pre-embedded reagents simultaneously. Summary of the Invention

[0004] In view of this, the main purpose of the present invention is to provide a liquid storage and release device that is low in cost, simple to operate, and can release multiple pre-embedded reagents simultaneously.

[0005] To achieve the above object, the technical solution of the present invention is achieved as follows:

[0006] The liquid storage and release device comprises: a pushing device, a liquid storage device and a chip; the liquid storage device is provided with a plurality of chambers, the pushing device extends into the liquid storage device, and the bottom of the pushing device is slidably connected to the liquid storage device;

[0007] One end of the liquid storage device is connected to the upper part of the pushing device by a buckle, and the other end of the liquid storage device is connected to the chip by a buckle.

[0008] In one embodiment, the pushing device includes: a pressing cover, a push rod and a piston, wherein the piston is fixedly connected to the tail of the push rod, the piston extends into the interior of the liquid storage device, and the piston is slidably connected to the liquid storage device so that one end of the liquid storage device is sealed;

[0009] The pressing cover is above the push rod, and the pressing cover is snap-connected with the liquid storage device.

[0010] In one embodiment, it further includes: a limiting device, which is arranged between the push rod and the piston.

[0011] In one embodiment, the liquid storage device includes: a liquid storage device body, a sample liquid storage chamber, and a reaction reagent liquid storage chamber, wherein the liquid storage device body is connected to the chip buckle, and the sample liquid storage chamber and the reaction reagent liquid storage chamber are opened inside the liquid storage device body;

[0012] The upper end of the sample liquid storage chamber is sealed by a sealing cover, and the lower end is sealed by aluminum foil; the upper end of the reaction reagent liquid storage chamber is sealed by a piston, and the lower end is sealed by aluminum foil.

[0013] In one embodiment, the liquid storage device further includes: a reaction reagent expansion chamber, which is opened inside the liquid storage device body; one end of the reaction reagent expansion chamber is sealed by a piston, and the other end is sealed by the liquid storage device; the reaction reagent expansion chamber is connected to the sample liquid storage chamber.

[0014] In one embodiment, a spike structure is provided inside the chip, and a plurality of the spike structures are provided and are located below the sample liquid storage cavity and the reaction reagent liquid storage cavity.

[0015] In one embodiment, the lower ends of the sample liquid storage chamber and the reaction reagent liquid storage chamber are made of plastic material, and the aluminum foil is hot-pressed and bonded to the lower ends of the sample liquid storage chamber and the reaction reagent liquid storage chamber.

[0016] In one embodiment, the sealing cover is made of plastic.

[0017] The liquid storage and release device of the present invention has the following beneficial effects:

[0018] The liquid storage and release device includes a pushing device, a liquid storage device, and a chip. The liquid storage device is provided with multiple chambers, and the pushing device extends into the liquid storage device, slidingly connecting the bottom of the pushing device to the liquid storage device. One end of the liquid storage device is connected to the buckle above the pushing device, and the other end of the liquid storage device is connected to the chip buckle. When using the liquid storage and release device to release liquid, the liquid storage device is first connected to the chip buckle, then the buckle above the pushing device is squeezed and the pushing device is pressed downward, so that the liquid in the multiple chambers inside the liquid storage device is released simultaneously, achieving the purpose of releasing the liquid to the device to be tested before testing.

[0019] The liquid storage and release device has a simple structure and is easy to operate, and can release multiple samples to be tested at the same time to achieve the technical effect of testing multiple samples at the same time. BRIEF DESCRIPTION OF THE DRAWINGS

[0020] In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the following briefly introduces the drawings required for use in the embodiments or the description of the prior art. Obviously, the drawings described below are only some embodiments of the present invention. For ordinary technicians in this field, other drawings can be obtained based on these drawings without paying any creative work.

[0021] Figure 1 An exploded view of a liquid storage and release device according to an embodiment of the present disclosure;

[0022] Figure 2 A front view of a liquid storage and release device according to an embodiment of the present disclosure;

[0023] Figure 3 A right side view of a liquid storage and release device according to an embodiment of the present disclosure;

[0024] Figure 4 Based on Figure 3 The AA line cross-sectional view is shown.

[0025]

Main component symbol description

[0026] 1. Pushing device; 11. Pressing cover; 12. Push rod; 13. Piston; 2. Liquid storage device; 21. Liquid storage device body; 22. Sample liquid storage chamber; 23. Reaction reagent liquid storage chamber; 24. Reaction reagent expansion chamber; 3. Chip; 4. Limiting device; 5. Sealing cover; 6. Aluminum foil; 7. Spike structure. DETAILED DESCRIPTION

[0027] The liquid storage and release device of the invention will be further described in detail below with reference to the accompanying drawings and embodiments of the invention.

[0028] It should be noted that, in the absence of conflict, the embodiments and features of the embodiments in this application can be combined with each other. The present invention will be described in detail below with reference to the accompanying drawings and in combination with the embodiments.

[0029] It should be noted that the terms used herein are only for describing specific embodiments and are not intended to limit the exemplary embodiments according to the present application. As used herein, unless the context clearly indicates otherwise, the singular form is also intended to include the plural form. In addition, it should be understood that when the terms "comprising" and / or "including" are used in this specification, they indicate the presence of features, steps, operations, devices, components and / or combinations thereof.

[0030] It should be noted that the terms "first", "second", etc. in the specification and claims of this application and the above-mentioned drawings are used to distinguish similar objects, and are not necessarily used to describe a specific order or sequence. It should be understood that the numbers used in this way can be interchangeable where appropriate, so that the embodiments of the present application described herein can, for example, be implemented in an order other than those illustrated or described herein. In addition, the terms "including" and "having" and any variations thereof are intended to cover non-exclusive inclusions. For example, a process, method, system, product or device that includes a series of steps or units is not necessarily limited to those steps or units clearly listed, but may include other steps or units that are not clearly listed or inherent to these processes, methods, products or devices.

[0031] For ease of description, spatially relative terms such as "above", "above", "on the upper surface", "on", etc. may be used herein to describe the spatial positional relationship of a device or feature to other devices or features as shown in the figures. It should be understood that the spatially relative terms are intended to encompass different orientations of the device in use or operation in addition to the orientation described in the figures. For example, if the device in the figures is inverted, the device described as "above" or "on top of" other devices or structures will be later positioned as "below" or "below" other devices or structures. Thus, the exemplary term "above" can include both the orientations of "above" and "below". The device may also be positioned in other different ways (rotated 90 degrees or in other orientations), and the spatially relative descriptions used herein will be interpreted accordingly.

[0032] like Figure 1-Figure 4 As shown, the liquid storage and release device includes: a pushing device 1, a liquid storage device 2 and a chip 3. A plurality of chambers are provided inside the liquid storage device 2, so that the pushing device 1 extends into the liquid storage device 2, and the bottom of the pushing device 1 is slidably connected to the liquid storage device 2. One end of the liquid storage device 2 is snap-connected to the top of the pushing device 1, and the other end of the liquid storage device 2 is snap-connected to the chip 1. When using the liquid storage and release device to release liquid, first snap-connect the liquid storage device 2 to the chip 3, then squeeze the snap on the top of the pushing device 1, and press the pushing device 1 downward, so that the liquid in the multiple chambers inside the liquid storage device 2 is released simultaneously, thereby achieving the purpose of releasing the liquid to the device to be tested before detection.

[0033] The liquid storage and release device has a simple structure and is easy to operate, and can release multiple samples to be tested at the same time to achieve the technical effect of testing multiple samples at the same time.

[0034] In a specific embodiment, the sample to be tested is a nucleic acid sample, and the specific sample collected is a throat swab.

[0035] In order to facilitate the release of the nucleic acid reagent, the pushing device 1 includes: a pressing cover 11, a push rod 12 and a piston 13. The piston 13 is fixedly connected to the tail of the push rod 12, and the piston 13 extends into the liquid storage device 2. The piston 13 is slidably connected to the liquid storage device 2, so that one end of the liquid storage device 2 is sealed.

[0036] The push-on cover 11 is positioned above the push rod 12 and is snap-connected to the liquid storage device 2. To release the nucleic acid reagent, the snap on the push-on cover 11 is pressed, and then the push-on cover 11 is pushed downward, driving the push rod 12 and piston 13. This pneumatic drive then forces the liquid into the chip 3. This liquid release mechanism is simple, and the liquid above the liquid storage device 2 is sealed by the piston 13, eliminating the need for additional sealing devices and significantly reducing sample testing costs.

[0037] In order to prevent premature release of liquid due to operational errors, the liquid storage and release device further includes a limiting device 4, which is provided between the push rod 22 and the piston 23. In a specific embodiment, the limiting device 4 is detachably connected to the top of the liquid storage device 2.

[0038] In order to achieve simultaneous release of liquids from different chambers, the liquid storage device 2 includes: a liquid storage device body 21, a sample liquid storage chamber 22, and a reaction reagent liquid storage chamber 23. The liquid storage device body 21 is snap-connected to the chip 3, and the sample liquid storage chamber 22 and the reaction reagent liquid storage chamber 23 are opened inside the liquid storage device body 21;

[0039] The upper end of the sample liquid storage chamber 22 is sealed by a sealing cover 5 , and the lower end is sealed by an aluminum foil 6 . The upper end of the second reaction reagent liquid storage chamber 23 is sealed by a piston 13 , and the lower end is sealed by an aluminum foil 6 .

[0040] Furthermore, the liquid storage device 2 also includes: a reaction reagent expansion chamber 24, the reaction reagent expansion chamber 24 is opened inside the liquid storage device body 21; one end of the reaction reagent expansion chamber 24 is sealed by the piston 13, and the other end is sealed by the liquid storage device 2; the reaction reagent expansion chamber 24 is connected to the sample liquid storage chamber 22. When storing the sample, the sealing cover 5 is opened, the sample liquid storage chamber 22 is filled with liquid reagent, the collected throat swab is placed in the sample liquid storage chamber 22, stirred, and then the sealing cover is re-covered. When releasing the liquid, the push rod 12 and the piston 13 in the reaction reagent liquid storage chamber 23 and the reaction reagent expansion chamber 24 are pneumatically driven to drive the liquid in the reaction reagent liquid storage chamber 23 and the sample liquid storage chamber 22 into the chip 3 to complete the detection of the sample.

[0041] To force the liquid in the reaction reagent reservoir 23 and the sample reservoir 22 into the interior of the chip 3, a plurality of spike structures 7 are provided within the chip 3, each located below the sample reservoir 22 and the reaction reagent reservoir 23. During the liquid release process, the aluminum foil 6 below the reaction reagent reservoir 23 and the sample reservoir 22 comes into contact with the spike structures 7, squeezing and puncturing the aluminum foil 6 to release the liquid.

[0042] In order to facilitate the sealing of the sample liquid storage chamber 22 and the reaction reagent liquid storage chamber 23, the lower ends of the sample liquid storage chamber 22 and the reaction reagent liquid storage chamber 23 are made of plastic material, and the aluminum foil 6 is hot-pressed and bonded to the lower ends of the sample liquid storage chamber 22 and the reaction reagent liquid storage chamber 23.

[0043] Furthermore, in order to improve the sealing effect of the sample liquid storage chamber 22 , the sealing cover 5 is made of plastic material.

[0044] The above are only preferred embodiments of the present invention and are not intended to limit the scope of protection of the present invention.

Claims

1. A liquid storage and release device, characterized in that include: A pushing device (1), a liquid storage device (2) and a chip (3); the liquid storage device (2) is provided with a plurality of chambers, the pushing device (1) extends into the liquid storage device (2), and the bottom of the pushing device (1) is slidably connected to the liquid storage device (2); One end of the liquid storage device (2) is snap-connected to the top of the pushing device (1), and the other end of the liquid storage device (2) is snap-connected to the chip (3); The liquid storage device (2) comprises: a liquid storage device body (21), a sample liquid storage cavity (22) and a reaction reagent liquid storage cavity (23); the liquid storage device body (21) is snap-connected to the chip (3); and the sample liquid storage cavity (22) and the reaction reagent liquid storage cavity (23) are provided inside the liquid storage device body (21); The upper end of the sample liquid storage chamber (22) is sealed by a sealing cover (5), and the lower end is sealed by an aluminum foil (6); the upper end of the reaction reagent liquid storage chamber (23) is sealed by a piston (13), and the lower end is sealed by an aluminum foil (6); A spike structure (7) is provided inside the chip (3), and a plurality of spike structures (7) are provided and are located below the sample liquid storage cavity (22) and the reaction reagent liquid storage cavity (23).

2. A liquid storage and release device according to claim 1, characterized in that: The pushing device (1) comprises: a pressing cover (11), a push rod (12) and a piston (13); the piston (13) is fixedly connected to the tail of the push rod (12); the piston (13) extends into the interior of the liquid storage device (2); the piston (13) is slidably connected to the liquid storage device (2), so that one end of the liquid storage device (2) is sealed; The pressing cover (11) is above the push rod (12), and the pressing cover (11) is snap-connected to the liquid storage device (2).

3. A liquid storage and release device according to claim 2, characterized in that: Also includes: A limiting device (4) is provided between the push rod (12) and the piston (13).

4. A liquid storage and release device according to claim 1, characterized in that: The liquid storage device (2) further comprises: a reaction reagent expansion chamber (24), the reaction reagent expansion chamber (24) being arranged inside the liquid storage device body (21); one end of the reaction reagent expansion chamber (24) being sealed by a piston (13), and the other end being sealed by the liquid storage device (2); and the reaction reagent expansion chamber (24) being in communication with the sample liquid storage chamber (22).

5. A liquid storage and release device according to claim 1, characterized in that: The lower ends of the sample liquid storage chamber (22) and the reaction reagent liquid storage chamber (23) are made of plastic material, and the aluminum foil (6) is hot-pressed and bonded to the lower ends of the sample liquid storage chamber (22) and the reaction reagent liquid storage chamber (23).

6. A liquid storage and release device according to claim 1, characterized in that: The sealing cover (5) is made of plastic.

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