An acupoint patch for promoting the absorption of subchorionic hematoma in the early pregnancy and its preparation method

Abstract

The present invention belongs to the technical field of traditional Chinese medicine, and specifically relates to an acupoint patch for promoting the absorption of subchorionic hematoma in the early stage of pregnancy. The acupoint patch comprises a traditional Chinese medicine composition, which is prepared by pulverizing the following raw materials and mixing them with vinegar: Eucommia ulmoides, Boehmeria nivea root, Psoralea corylifolia, Artemisia argyi carbon, Cassia obtusifolia, Rheum palmatum, Areca catechu, Foeniculum vulgare, Akebia quinata, Zanthoxylum bungeanum, Syzygium aromaticum, Cinnamomum cassia, stir-fried Atractylodes macrocephala. The present invention uses the external treatment method of traditional Chinese medicine to treat subchorionic hematoma in the early stage of pregnancy. The traditional Chinese medicine patch used has remarkable curative effect, is safe and convenient, and has a wide range of applications.

Description

Technical Field

[0001] The present invention relates to the technical field of traditional Chinese medicine, and particularly to an acupoint patch for promoting the absorption of subchorionic hematoma in the early pregnancy and a preparation method thereof. Background Art

[0002] Subchorionic hematoma (SCH) refers to the separation and bleeding between the chorionic plate and the decidua basalis, causing blood to accumulate between the chorion and the decidua basalis to form a hematoma. Early pregnancy threatened abortion is one of the common diseases in obstetrics and gynecology. In recent years, the incidence of spontaneous abortion has shown an increasing trend year by year. Its main clinical manifestations are a small amount of vaginal bleeding, abdominal distension, soreness in the waist accompanied by a feeling of falling in the lower abdomen; or the cervix of the patient is not opened, the fetal membrane is intact and has not been damaged, and the pregnancy product has not been discharged; the duration of amenorrhea is consistent with the size of the uterus. Its etiology and pathogenesis are not yet clear. Some scholars believe that during the invasion of the outer layer of the chorion of the fetal membrane into the decidua in the early pregnancy, due to the imbalance of the maternal immune system, the expression of protective cytokines is inhibited, and the expression of damaging cytokines is overexpressed, resulting in abnormal coagulation function of the decidua blood vessels; at the same time, a large amount of proteolytic enzymes are released by the syncytiotrophoblast on the outer layer of the chorion, causing the rupture of the decidua blood vessels, resulting in bleeding between the decidua and the chorion, and finally forming blood accumulation and placental membrane detachment. Subchorionic hematoma is a common complication of early threatened abortion. Ultrasound shows a crescent, triangular or irregular high-gray area, hypoechoic or anechoic area between the gestational sac and the uterine wall. Subchorionic hematoma can occur at all stages of pregnancy. Some studies have shown that the incidence of this disease is as high as 48%. If the disease is intervened earlier, the prognosis is generally better.

[0003] At present, the main treatment of this disease with western medicine is to supplement progesterone, add hemostatic agents, and add drugs to inhibit uterine contractions (phloroglucinol) for those with lower abdominal pain. For subchorionic hematoma that does not disappear for a long time, antibiotics are added for anti-infection and anti-inflammatory treatment. The modern doctor He Shaoshan often adds a small amount of traditional Chinese medicine for promoting blood circulation and removing blood stasis in the treatment of pregnancy complicated with subchorionic hematoma, and has achieved good clinical results. Professor Luo Songping believes that the main pathogenesis of subchorionic hematoma during pregnancy is kidney deficiency and blood stasis. Therefore, when treating this disease, the basic treatment principles are to strengthen the kidney and prevent miscarriage, and promote blood circulation to remove blood stasis, and the effects are obvious by promoting blood circulation to remove blood stasis and preventing miscarriage simultaneously. Professor Chu Yuxia believes that the main pathogenesis of subchorionic hematoma during pregnancy is deficiency of the spleen and kidney, yin deficiency and blood heat, and concurrent blood stasis. Clinically, the main treatment principles are to invigorate the spleen and tonify the kidney, cool the blood and promote blood circulation to remove blood stasis. The commonly used modified Chu's anti-abortion prescription (Cuscuta chinensis, Dipsacus asper, Atractylodes macrocephala, Chinese yam, Sanguisorba officinalis, Eclipta prostrata, Colla Corii Asini, Perilla stem, Amomum villosum, Salvia miltiorrhiza, Scutellaria baicalensis, roasted licorice) is often used. Feng Lina et al. treated 30 cases of pregnancy complicated with subchorionic hematoma with the method of strengthening the kidney to prevent miscarriage, promoting blood circulation to remove blood stasis, and the effective rate was 93.3%. Shao Rong et al. used dydrogesterone tablets, intramuscular injection of HCG needles, and orally administered traditional Chinese medicine Yigu Baotai Decoction for patients with pregnancy complicated with intrauterine fluid accumulation after IVF-ET, and the success rate of fetal protection was 77.78%.

[0004] However, most of the above-mentioned treatment methods adopt traditional Chinese medicine oral prescriptions, and there is still little research on the external treatment method of traditional Chinese medicine for early pregnancy chorionic hematoma. Summary of the Invention

[0005] The object of the present invention is to provide an acupoint patch for promoting the absorption of chorionic hematoma in the early pregnancy. The present invention uses the external treatment method of traditional Chinese medicine to treat early pregnancy chorionic hematoma. It has a significant therapeutic effect on the formation of hematoma caused by the downward aggregation of yin blood to nourish the fetus after pregnancy, the more prosperous blood heat due to yin blood deficiency, the heat lurking in Chong and Ren meridians, the excessive yang and blood heat, the overflow of blood due to heat, and the forced blood to flow erratically. It has the functions of stopping bleeding and preventing miscarriage, and the traditional Chinese medicine patch adopted has remarkable curative effect, is safe and convenient, and has a wide range of applications.

[0006] To achieve the above object, the technical solution adopted by the present invention is as follows:

[0007] An acupoint patch for promoting the absorption of chorionic hematoma in the early pregnancy, characterized in that the acupoint patch comprises a traditional Chinese medicine composition, and the traditional Chinese medicine composition is made by grinding the following raw materials and mixing them with vinegar: Eucommia ulmoides, Boehmeria nivea root, Psoralea corylifolia, Artemisia argyi carbon, Cassia obtusifolia, Rheum officinale, Areca catechu, Foeniculum vulgare, Akebia quinata, Zanthoxylum bungeanum, Eugenia caryophyllata, Cinnamomum cassia, stir-fried Atractylodes macrocephala.

[0008] Preferably, by mass ratio, Eucommia ulmoides: Boehmeria nivea root: Psoralea corylifolia: Artemisia argyi carbon: Cassia obtusifolia: Rheum officinale: Areca catechu: Foeniculum vulgare: Akebia quinata: Zanthoxylum bungeanum: Eugenia caryophyllata: Cinnamomum cassia: stir-fried Atractylodes macrocephala is 30-60: 20-40: 20-40: 10-20: 15-30: 30-60: 15-30: 20-40: 10-20: 10-20: 10-20: 10-20: 15-30.

[0009] Preferably, by mass ratio, Eucommia ulmoides: Boehmeria nivea root: Psoralea corylifolia: Artemisia argyi carbon: Cassia obtusifolia: Rheum officinale: Areca catechu: Foeniculum vulgare: Akebia quinata: Zanthoxylum bungeanum: Eugenia caryophyllata: Cinnamomum cassia: stir-fried Atractylodes macrocephala is 3: 2: 2: 1: 1.5: 3: 1.5: 2: 1: 1: 1: 1: 1.5.

[0010] The present invention also claims the manufacturing method of the acupoint patch for promoting the absorption of chorionic hematoma in the early pregnancy, weighing each traditional Chinese medicine, grinding them into powder, then adding vinegar to make a paste, and then evenly coating the paste-like traditional Chinese medicine composition on a gauze patch, and then covering another layer of gauze patch to obtain it.

[0011] Preferably, the thickness of the coated paste-like traditional Chinese medicine composition is about 5 mm.

[0012] The present invention also protects the acupoint patch for promoting the absorption of chorionic hematoma in the early pregnancy obtained by the above manufacturing method and the using method of the acupoint patch.

[0013] Preferably, the usage method is to remove the upper gauze patch of the acupoint patch and apply it to the abdomen, covering the Shenque acupoint upwards and the Guanyuan acupoint downwards, within the range of three inches beside the midline of the umbilicus.

[0014] In the present invention, the properties and functions of the traditional Chinese medicines used are as follows:

[0015] Eucommia ulmoides: It is sweet and warm in nature, enters the liver and kidney meridians, can tonify the liver and kidney, strengthen tendons and bones, and prevent miscarriage. It is an excellent medicine for treating threatened abortion or fetal movement restlessness. It has functions such as sedation, immune regulation, antioxidant, anti-fatigue, antiviral, antibacterial, and neuroprotection, and has antibacterial effects on Staphylococcus aureus, Escherichia coli, and Salmonella to varying degrees.

[0016] Fennel: It is pungent and warm in nature and flavor, and belongs to the liver, kidney, spleen, and stomach meridians. It has the effects of dispelling cold and relieving pain, regulating qi and harmonizing the stomach. Hot compress can relieve constipation and abdominal distension, reduce abdominal pain, and stop bleeding. It has certain effects on the human internal organ system, central nervous system, cardiovascular system, endocrine system, immune system, and chemotherapy, including regulating gastrointestinal function, analgesia, anti-inflammatory, anti-hepatotoxic and nephrotoxic effects, reducing blood lipid, reducing blood sugar, antioxidant, antibacterial, antiviral, anti-tumor, regulating estrogen level and other functional activities.

[0017] Zanthoxylum bungeanum: It is pungent, dispersing, warm and dry in nature, enters the spleen and stomach, can warm the middle-jiao to relieve pain and relieve itching, and has pharmacological effects such as analgesia, anti-inflammatory, promoting skin absorption, local anesthesia, antibacterial, antioxidant, and dispelling wind and dampness.

[0018] Clove: It is pungent and warm in nature, has the effects of warming the middle-jiao to reduce adverse qi and tonifying the kidney to assist yang, and has various effects such as antibacterial and anti-inflammatory, antipyretic and analgesic, antioxidant, anti-ulcer, anesthesia, promoting transdermal absorption, and neuroprotection.

[0019] Cinnamon: It is pungent, sweet and warm in nature, and belongs to the kidney and spleen meridians. It can lead fire back to its origin, dispel cold and relieve pain, and tonify fire and assist yang. It has various pharmacological effects such as antibacterial effect, anti-inflammatory, antioxidant, neuroprotection, hypoglycemic, lipid-lowering, and uric acid-lowering. It also has functions such as freshness preservation, deodorization, and good fragrance retention.

[0020] Psoralea corylifolia: It is bitter, pungent and warm in nature, can warm the spleen and kidney, and astringe essence. Pharmacological research has proved that it has good anti-tumor, antioxidant, antibacterial, anti-inflammatory, antidepressant, regulating estrogen level, promoting bone growth, liver protection, blood vessel protection, and neuroprotection effects.

[0021] Artemisia argyi carbon: It is warm in nature, can warm the meridians and warm the uterus, stop bleeding and prevent miscarriage, and has various pharmacological activities such as hemostasis, anti-fungal, antiviral, anti-tumor, and antioxidant. It has good curative effects on treating threatened abortion with symptoms of lower abdominal pain and vaginal bleeding.

[0022] Akebia quinata: It is bitter in taste and cold in nature, belongs to the heart, small intestine, and bladder meridians, can clear the heart and remove vexation, and promote diuresis. It has the effects of anti-inflammatory, antibacterial, and promoting diuresis.

[0023] Ramie root: It is sweet, cold in nature, cooling blood for hemostasis and preventing miscarriage. Ramie root can treat miscarriage through immune, coagulation, apoptosis, and nervous system regulation, with good effects and wide application in preventing miscarriage.

[0024] Areca nut: It is pungent, bitter, and warm in nature, promoting qi flow, relieving food retention, and promoting diuresis. Its pharmacological effects mainly include promoting gastrointestinal motility, anti-inflammatory and analgesic, antibacterial and bacteriostatic, anti-fatigue, antidepressant, anti-aging, antioxidant, hypoglycemic, and regulating blood lipid.

[0025] Cassia seed: It tastes sweet, bitter, and salty, and belongs to the liver and large intestine meridians. It can clear heat and moisten the intestines for defecation. It contains various chemical components and shows various pharmacological activities, such as regulating gastrointestinal function, antibacterial, protecting the liver and improving eyesight, bacteriostatic, antioxidant, antihypertensive, and regulating blood lipid.

[0026] Rhubarb: It is bitter and cold in nature, belonging to the spleen, stomach, and large intestine meridians. It can clear heat and purge fire, cool blood for hemostasis, and remove blood stasis and dredge meridians. It can be used for those with swelling pain or bleeding due to blood stasis and heat, especially those with constipation or uncomfortable defecation.

[0027] Compared with the prior art, the beneficial effects of the present invention are as follows:

[0028] (1) In the whole formula of the present invention, a large amount of ramie root is used, and the cold nature of Akebia quinata is taken to enter the heart meridian of the shaoyin, reducing heart fire, clearing heat and stopping bleeding to prevent miscarriage. At the same time, Eucommia ulmoides, Psoralea corylifolia, and Artemisia argyi charcoal are combined to enter the kidney meridian of the shaoyin, tonifying the liver and kidney, warming the kidney and boosting yang, increasing the operation of qi, blood, and body fluids in the body, improving metabolism, and promoting the absorption of hematoma while stopping bleeding. The above drugs are used with both cold and heat properties, so as to achieve the balance of water and fire, preventing miscarriage and stopping bleeding. Fennel, Chinese prickly ash, clove, and cinnamon can not only enhance the effect of warming the kidney but also promote transdermal absorption and increase the utilization rate of drugs. Areca nut, cassia seed, and rhubarb promote qi flow and defecation, enhance gastrointestinal motility, improve digestive tract function, reduce constipation, make the stool smooth, and prevent the increase of abdominal pressure caused by constipation, thus avoiding further bleeding due to uterine compression. The above combination of traditional Chinese medicines together exerts the effect of stopping bleeding and preventing miscarriage.

[0029] (2) The present invention has a significant therapeutic effect on the treatment of hematoma formed due to the downward aggregation of yin blood to nourish the fetus after pregnancy, the more prosperous blood heat caused by yin blood deficiency, the heat lurking in the thoroughfare and conception vessels, the excessive yang and blood heat, the blood overflowing due to heat, and the forced and reckless movement of blood. Its therapeutic effect is not inferior to that of western medicine.

[0030] (3) The present invention is a traditional Chinese medicine acupoint patch for treating subchorionic hematoma in the early pregnancy by external application of traditional Chinese medicine. During the use process, it has very little side effect on pregnant women, is safe and convenient, and has wide application. BRIEF DESCRIPTION OF THE DRAWINGS

[0031] Figure 1 is the actual application of an acupoint patch for promoting the absorption of subchorionic hematoma in the early pregnancy of the present invention Figure 1 ;

[0032] Figure 2 is the actual application of an acupoint patch for promoting the absorption of subchorionic hematoma in the early pregnancy of the present inventionFigure 2 。 Detailed implementation manners

[0033] In order to enable those skilled in the art to better understand the solution of the present invention, the technical solutions in the embodiments of the present invention will be clearly and completely described below. Obviously, the described embodiments are only a part of the embodiments of the present invention, rather than all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those of ordinary skill in the art without making creative efforts shall fall within the protection scope of the present invention.

[0034] It should be noted that the terms "first", "second", etc. in the description and claims of the present invention are used to distinguish similar objects, and do not necessarily need to describe a specific order or sequence. It should be understood that such used data can be interchanged under appropriate circumstances so that the embodiments of the present invention described here can be implemented in an order other than those illustrated or described here. In addition, the terms "comprising" and "having" and any variations thereof are intended to cover non-exclusive inclusion. For example, a process, method, system, product or device comprising a series of steps or units does not necessarily have to be limited to those clearly listed steps or units, but may include other steps or units not clearly listed or inherent to these processes, methods, products or devices.

[0035] Embodiment 1

[0036] A method for making an acupoint patch for promoting the absorption of subchorionic hematoma in the early stage of pregnancy, the specific steps are as follows: weigh 30 parts of eucommia ulmoides, 20 parts of ramie root, 20 parts of psoralea corylifolia, 10 parts of carbonized mugwort leaf, 15 parts of cassia seed, 30 parts of rhubarb, 15 parts of areca nut, 20 parts of fennel, 10 parts of akebia quinata, 10 parts of Chinese prickly ash, 10 parts of cloves, 10 parts of cinnamon, 15 parts of stir-fried atractylodes macrocephala, grind the traditional Chinese medicines into powder, then add vinegar to reconcile into a paste, then evenly coat the paste-like traditional Chinese medicine composition on a gauze patch, and then cover it with another gauze patch to obtain.

[0037] Embodiment 2

[0038] A method for making an acupoint patch for promoting the absorption of subchorionic hematoma in the early stage of pregnancy, the specific steps are as follows: weigh 40 parts of eucommia ulmoides, 30 parts of ramie root, 30 parts of psoralea corylifolia, 15 parts of carbonized mugwort leaf, 20 parts of cassia seed, 45 parts of rhubarb, 20 parts of areca nut, 30 parts of fennel, 15 parts of akebia quinata, 15 parts of Chinese prickly ash, 15 parts of cloves, 15 parts of cinnamon, 20 parts of stir-fried atractylodes macrocephala, grind the traditional Chinese medicines into powder, then add vinegar to reconcile into a paste, then evenly coat the paste-like traditional Chinese medicine composition on a gauze patch, and then cover it with another gauze patch to obtain.

[0039] Embodiment 3

[0040] A method for preparing an acupoint patch for promoting the absorption of subchorionic hematoma in the early stage of pregnancy, the specific steps are as follows: Weigh 50 parts of Eucommia ulmoides, 35 parts of Boehmeria nivea root, 35 parts of Psoralea corylifolia, 15 parts of carbonized Artemisia argyi, 25 parts of Cassia obtusifolia, 50 parts of Rheum officinale, 25 parts of Areca catechu, 35 parts of Foeniculum vulgare, 15 parts of Akebia quinata, 15 parts of Zanthoxylum bungeanum, 15 parts of Eugenia caryophyllata, 15 parts of Cinnamomum cassia, 25 parts of stir-fried Atractylodes macrocephala, grind the traditional Chinese medicines into powder, then add vinegar to reconcile into a paste, then evenly coat the paste-like traditional Chinese medicine composition on a gauze patch, and then cover it with another layer of gauze patch to obtain the product.

[0041] Example 4

[0042] A method for preparing an acupoint patch for promoting the absorption of subchorionic hematoma in the early stage of pregnancy, the specific steps are as follows: Weigh 60 parts of Eucommia ulmoides, 60 parts of Boehmeria nivea root, 60 parts of Psoralea corylifolia, 20 parts of carbonized Artemisia argyi, 30 parts of Cassia obtusifolia, 60 parts of Rheum officinale, 30 parts of Areca catechu, 40 parts of Foeniculum vulgare, 40 parts of Akebia quinata, 40 parts of Zanthoxylum bungeanum, 40 parts of Eugenia caryophyllata, 40 parts of Cinnamomum cassia, 30 parts of stir-fried Atractylodes macrocephala, grind the traditional Chinese medicines into powder, then add vinegar to reconcile into a paste, then evenly coat the paste-like traditional Chinese medicine composition on a gauze patch, and then cover it with another layer of gauze patch to obtain the product.

[0043] Application example

[0044] 1. Case selection: Select patients who received fetal protection treatment in the Department of Traditional Chinese Medicine of Hubei Maternal and Child Health Hospital from July 2020 to July 2022. Observe 120 patients with threatened abortion in early pregnancy complicated with subchorionic hematoma, and divide them into two groups, namely Group A and Group B, with 60 patients in each group. The general data of the two groups of patients in terms of age, average number of abortions, average abortion and current gestational week numbers were analyzed statistically, and the differences were not statistically significant (all P>0.05), and the groups were comparable. See Table 1 for details.

[0045] Table 1 Comparison of the average age, average number of abortions, average abortion and current gestational week numbers of pregnant patients

[0046]

[0047] The comparison between the two groups showed P>0.05, with no significant differences and no statistical significance. It indicates that the two groups are comparable.

[0048] 2. Diagnostic criteria: (1) Diagnostic criteria for threatened abortion in early pregnancy: refer to "Obstetrics and Gynecology" and "Clinical Guidelines for New Chinese Medicines (Trial)": ① A small amount of vaginal bleeding occurs before the 12th week of pregnancy, no pregnancy products are discharged, and lower abdominal pain or back pain occurs successively; ② Gynecological examination shows that the cervix is not dilated and the size of the uterus is consistent with the number of weeks of amenorrhea; ③ B-ultrasound examination shows that the size of the uterus, gestational sac, embryo or fetus is consistent with the gestational age. (2) Diagnostic criteria for subchorionic hematoma: refer to "Obstetrics and Gynecology Ultrasound Atlas", B-ultrasound images show an echo-free area between the uterine wall and the gestational sac in the uterine cavity, and the shape is mostly crescent, triangle or polygonal.

[0049] (1) Inclusion criteria: ① Meet the diagnostic criteria for threatened abortion in early pregnancy; ② Subchorionic hematoma on B-ultrasound examination; ③ Age 20 to 40 years old; ④ Voluntary to accept the treatment of this trial, no major diseases of the heart, liver, kidney and other organs, and the spouse is in good health (especially no organic lesions of the reproductive system); ⑤ Sign the informed consent form.

[0050] (2) Exclusion criteria: ① Patients with ≥ 3 consecutive spontaneous abortions; ② Patients infected with rubella, cytomegalovirus, toxoplasmosis, or herpes simplex virus; ③ Patients with severe anemia, heart failure, chronic nephritis, hypertension, diabetes, or systemic infection such as high fever; ④ Patients with uterine malformation, uterine fibroids, or adenomyosis; ⑤ Patients with untreated intrauterine adhesions, intrauterine effusions, endometrial polyps, or endometrial hyperplasia; ⑥ Patients with mental illness; ⑦ Patients who cannot adhere to the course of treatment.

[0051] 3. Treatment methods:

[0052] Group A: The patients started to receive traditional pregnancy-preserving treatment from the time of consultation, using progesterone injection (National Medicine Standard No. H33020828, Zhejiang Xianjun Pharmaceutical Co., Ltd., 20 mg / vial, adjusted to 20-60 mg according to the condition, once a day) + dydrogesterone tablets (registration number H20170221, Abbott Healthcare Products BV, the Netherlands, 10 mg / tablet, adjusted according to the condition, 1 tablet each time, 3 times a day) until the subchorionic hematoma disappeared.

[0053] Group B: The patient lies in supine or sitting position, and the upper gauze patch of the multiple acupoint patches prepared in Example 1 is removed. The actual application of the patch is as follows: Figures 1 to 2 As shown, apply on the abdomen from Shenque point up to Guanyuan point down, three inches away from the midline of the navel, twice a day, 5 days as a course of treatment, 5 courses of treatment are required.

[0054] 4. Efficacy evaluation: (1) Color ultrasound examination: The ultrasonic instrument used is the GE Voluson 730 three-dimensional color Doppler ultrasound instrument, with an abdominal probe frequency of 3.5 MHz. A specialized doctor operates to measure the bilateral uterine arteries, the area of subchorionic hematoma, and the area of gestational sac of the patient through transvaginal color Doppler ultrasound before treatment, 10 days after treatment, 18 days after treatment, and 25 days after treatment. (2) The SPSS 22.0 statistical software is used for data analysis. First, normality and homogeneity of variance tests are performed. Measurement data conforming to normal distribution are expressed as mean ± standard deviation (x-±s). The t-test for two independent samples is used for comparison between two groups, and the paired-sample t-test is used for comparison before and after treatment within the group. Non-parametric rank sum test is used for non-normal distribution; the rank sum test for rank data is used for comparison of clinical efficacy, and the X test is used for comparison of count data. A P < 0.05 is considered statistically significant.

[0055] 5. Treatment results:

[0056] Table 2 Comparison of the area of subchorionic hematoma in two groups of patients before treatment, 10 days after treatment, 18 days after treatment, and 25 days after treatment

[0057]

[0058] Table 3 Comparison of pregnancy outcomes in two groups of patients

[0059]

[0060] From the above evaluation results, it can be seen that the acupoint patch for hematoma absorption prepared by the present invention has better effects compared with western medicine treatment, with significant curative effects. Moreover, the external traditional Chinese medicine patch is safer and more convenient, and has greater comprehensive significance for fetal protection treatment.

[0061] The above is only a preferred specific embodiment of the present invention, and the protection scope of the present invention is not limited thereto. Any simple change or equivalent replacement of the technical solutions that can be obviously obtained by those skilled in the art within the technical scope disclosed by the present invention all fall within the protection scope of the present invention.

Claims

1. An acupoint patch for promoting the absorption of subchorionic hematoma in the early pregnancy, characterized in that, The acupoint patch is made of a traditional Chinese medicine composition, which is made by pulverizing the following raw materials and mixing them with vinegar: Eucommia ulmoides Oliv., Boehmeria nivea roots, Psoralea corylifolia L., Artemisia argyi Levl. et Vant. carbonized, Cassia obtusifolia L., Rheum palmatum L., Areca catechu L., Foeniculum vulgare Mill., Akebia quinata (Thunb.) Decne., Zanthoxylum bungeanum Maxim., Eugenia caryophyllata Thunb., Cinnamomum cassia Presl., stir-fried Atractylodes macrocephala Koidz. In terms of mass ratio, the traditional Chinese medicine composition is Eucommia ulmoides Oliv.: Boehmeria nivea roots: Psoralea corylifolia L.: Artemisia argyi Levl. et Vant. carbonized: Cassia obtusifolia L.: Rheum palmatum L.: Areca catechu L.: Foeniculum vulgare Mill.: Akebia quinata (Thunb.) Decne.: Zanthoxylum bungeanum Maxim.: Eugenia caryophyllata Thunb.: Cinnamomum cassia Presl.: stir-fried Atractylodes macrocephala Koidz. = 30 - 60:20 - 40:20 - 40:10 - 20:15 - 30:30 - 60:15 - 30:20 - 40:10 - 20:10 - 20:10 - 20:10 - 20:15 - 30.

2. The acupoint patch according to claim 1, characterized in that, In terms of mass ratio, Eucommia ulmoides Oliv.: Boehmeria nivea roots: Psoralea corylifolia L.: Artemisia argyi Levl. et Vant. carbonized: Cassia obtusifolia L.: Rheum palmatum L.: Areca catechu L.: Foeniculum vulgare Mill.: Akebia quinata (Thunb.) Decne.: Zanthoxylum bungeanum Maxim.: Eugenia caryophyllata Thunb.: Cinnamomum cassia Presl.: stir-fried Atractylodes macrocephala Koidz. = 3:2:2:1:1.5:3:1.5:2:1:1:1:1:1.

5.

3. A method for preparing an acupoint patch for promoting the absorption of subchorionic hematoma in the early pregnancy according to any one of claims 1-2, characterized in that, Weigh each traditional Chinese medicine and grind it into powder, then add vinegar and mix it into a paste. Then evenly coat the paste of the traditional Chinese medicine composition on a gauze patch, and then cover it with another layer of gauze patch to obtain the product.

4. The manufacturing method according to claim 3, characterized in that, The thickness of the coated paste of the traditional Chinese medicine composition is about 5 mm.

5. An acupoint patch for promoting the absorption of subchorionic hematoma in the early pregnancy, which is prepared by the production method according to any one of claims 3 - 4.

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