Sodium alginate-pectin aerogel and preparation method and application thereof
Sodium alginate-pectin aerogel was prepared by emulsification gelation and internal coagulation methods, which solved the problems of low concentration and poor stability of alginate microspheres at the mucosal absorption site in the existing technology. This method achieves efficient mucosal targeted drug delivery and drug stability, and is suitable for various mucosal drug delivery routes.
CN117447762BActive Publication Date: 2026-07-03DONGWOTONGTAI (FENGCHENG) BIOENGINEERING CO LTD
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- DONGWOTONGTAI (FENGCHENG) BIOENGINEERING CO LTD
- Filing Date
- 2023-03-21
- Publication Date
- 2026-07-03
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Figure CN117447762B_ABST
Abstract
This invention provides a sodium alginate-pectin aerogel, its preparation method, and its applications, relating to the field of gel materials technology. This invention employs an emulsification gelation method and an internal coagulation method to prepare the sodium alginate-pectin aerogel. In this invention, pectin and sodium alginate have better interaction; the addition of pectin increases the degree of cross-linking between the two polysaccharides, resulting in a higher specific surface area for the sodium alginate-pectin aerogel. The sodium alginate-pectin aerogel provided by this invention has a high specific surface area and can carry a large amount of drug; it can serve as a novel mucosal targeted drug delivery carrier, as it does not alter cell growth and is a non-cytotoxic material.
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