Pharmaceutical emulsification reactor

Abstract

The application relates to the technical field of chemical pharmacy, and provides an emulsification reaction kettle for pharmacy, which comprises a reaction kettle body, a stirring assembly, a feeding port and a discharging port formed in the reaction kettle body, and the feeding port and the discharging port can be opened or closed; the stirring assembly comprises a stirring shaft and a first driving piece for driving the stirring shaft to rotate, the first driving piece is arranged outside the reaction kettle body, the stirring shaft is rotationally arranged in the reaction kettle body, and a heating sheet is arranged on the stirring shaft; a heat exchange shell is arranged outside the reaction kettle body, a heat exchange interlayer is formed between the inner side wall of the heat exchange shell and the outer side wall of the reaction kettle body, and a heat exchange inlet and a heat exchange outlet are formed in the heat exchange shell. The application can improve the heating uniformity of materials in the reaction kettle.

Description

Technical Field

[0001] This application relates to the technical field of chemical pharmaceuticals, and in particular to an emulsifying reactor for pharmaceutical use. Background Technology

[0002] Emulsifying reactors are important pieces of equipment in the pharmaceutical industry, used for emulsification reactions to produce drugs, cosmetics, food additives, and other products. The main function of an emulsifying reactor is to provide a sealed reaction environment that allows different liquid or solid materials to mix and react uniformly.

[0003] The working principle of an emulsification reactor is mainly to disperse liquid materials into tiny droplets or particles through mechanical stirring and the action of emulsifiers, thereby increasing their surface area and promoting the reaction rate. Simultaneously, the emulsification reactor also has heating and cooling functions, which can control the reaction temperature and ensure the reaction proceeds under optimal conditions.

[0004] In the pharmaceutical industry, emulsifying reactors are commonly used in processes such as drug synthesis, drug dispersion, drug dissolution, and drug crystallization. For example, in the preparation of liposome drugs, emulsifying reactors can uniformly mix liposome materials and drugs, and by controlling reaction conditions, achieve drug encapsulation and targeted delivery.

[0005] A common method for temperature control in emulsification reactors is to install a heat exchange circulating medium on the outer wall of the reactor, using the reciprocating flow of hot and cold media to change the reactor temperature. However, when processing high-concentration emulsions, due to the poor fluidity of the emulsion, the heat exchange effect is uneven for materials near the reactor sidewalls, while the heat exchange effect is poor for materials in the middle of the reactor. This results in uneven heat exchange within the reactor, affecting the emulsification effect. Summary of the Invention

[0006] In order to improve the uniformity of heating of materials in the reactor, this application provides a pharmaceutical emulsification reactor.

[0007] This application provides a pharmaceutical emulsification reactor, which adopts the following technical solution:

[0008] A pharmaceutical emulsification reactor, comprising:

[0009] The reactor body has an inlet and an outlet, both of which can be opened or closed.

[0010] A stirring assembly, comprising a stirring shaft and a first driving member for driving the stirring shaft to rotate, the first driving member being disposed outside the reactor body, the stirring shaft being rotatably disposed inside the reactor body, and a heating element being disposed on the stirring shaft;

[0011] The reactor body is provided with a heat exchange shell, and a heat exchange interlayer is formed between the inner wall of the heat exchange shell and the outer wall of the reactor body. The heat exchange shell is provided with a heat exchange inlet and a heat exchange outlet.

[0012] By adopting the above technical solution, the operator can add the materials to be mixed into the reactor body through the feed inlet. Activating the first drive unit will rotate the stirring shaft, stirring the materials inside the reactor body and dispersing them into small particles for thorough reaction. When heating of the materials inside the reactor body is required, a high-temperature medium is introduced into the heat exchange jacket through the heat exchange inlet. The high-temperature medium exchanges heat with the materials inside the reactor and then exits from the heat exchange outlet, achieving circulating heat exchange. Simultaneously, the heating elements are activated to directly heat the inside of the reactor, achieving uniform heating of the materials inside. This internal and external mixed heating method improves the heating uniformity of the materials inside the reactor body.

[0013] Optionally, a first guide plate is provided inside the heat exchange jacket. The first guide plate is spirally wound around the outer wall of the reactor body. The heat exchange inlet and the heat exchange outlet are located at both ends of the heat exchange shell.

[0014] By adopting the above technical solution, a first guide plate is installed inside the heat exchange jacket, and the first guide plate is spirally arranged around the outside of the reactor body, forming a spiral channel for the flow of the heat exchange medium within the heat exchange jacket. The heat exchange medium enters the heat exchange jacket through the heat exchange inlet and flows along the spiral channel to the heat exchange outlet. On the one hand, the arrangement of the first guide plate facilitates the filling of the entire heat exchange jacket with the heat exchange medium; on the other hand, it prolongs the residence time of the heat exchange medium within the heat exchange jacket, allowing the heat exchange medium to achieve sufficient heat exchange with the materials inside the reactor body.

[0015] Optionally, the heat exchange jacket is covered with an insulation shell, and an insulation jacket is formed between the inner wall of the insulation shell and the inner wall of the insulation shell.

[0016] By adopting the above technical solution, the insulation jacket is set to improve the insulation performance of the reactor body and improve the stability of the reaction temperature, thereby ensuring the smooth progress of the reaction; while reducing heat loss, it can also reduce the influence of the external ambient temperature on the reactor body.

[0017] Optionally, a heat exchange tank is provided on the reactor body, and the heat exchange tank is located in the middle of the reactor body;

[0018] A sealing plate is provided at the opening of the heat exchange tank, and an auxiliary heat exchange cavity is formed between the sealing plate and the heat exchange tank. A temperature control inlet and a temperature control outlet are provided on the sealing plate.

[0019] By adopting the above technical solution, an auxiliary heat exchange chamber is formed in the middle of the reactor body through the setting of the heat exchange tank. The heat exchange medium is filled into the auxiliary heat exchange chamber from the temperature control inlet. The heat exchange medium moves to the middle of the reactor body through the auxiliary heat exchange chamber and exchanges heat with the material located in the middle of the reactor body, thereby further improving the heating uniformity of the material in the reactor body.

[0020] Optionally, the heat exchange tank is provided with multiple flow pipes, both ends of which are connected to the interior of the reactor body.

[0021] By adopting the above technical solution, multiple flow pipes are installed in the heat exchange tank, and both ends of the flow pipes are connected to the inside of the reactor body. When the material inside the reactor body passes through the flow pipes under the action of the stirring shaft, the multiple flow pipes shear the material to improve the mixing effect of the material inside the reactor body.

[0022] Optionally, the flow tube is bent upwards.

[0023] By adopting the above technical solution, the flow tube is bent upward, so that the material entering the flow tube can flow along the tube wall to the outside of the flow tube, thereby reducing the material residue in the flow tube.

[0024] Optionally, a filter plate is slidably disposed inside the reactor body, and a second driving member is disposed outside the reactor body for driving the filter plate to slide in the vertical direction.

[0025] By adopting the above technical solution, after the stirring component has been running for a period of time, the filter plate is driven to slide vertically upward by the second driving component. If there are lumps in the reactor body, the lumps will affect the heating effect of the material in the reactor body. The upward sliding of the filter plate can filter out the lumps from the material, which is beneficial to the normal reaction of the material in the reactor body.

[0026] Optionally, a waste collection box is connected to one side of the reactor body, and an observation window is provided on the waste collection box; a waste pusher plate is slidably disposed inside the reactor body, and a third driving component is provided on the reactor body for driving the waste pusher plate to slide.

[0027] By adopting the above technical solution, after the filter plate transports the agglomerated material in the reactor body to the waste collection box, the third driving component drives the waste pusher plate to move closer to the waste collection box, and the waste pusher pushes the agglomerated material on the filter plate into the waste collection box. Operators can observe the collection of agglomerated material in the waste collection box through the observation window and adjust the emulsion environment of the material in the reactor body in a timely manner according to the agglomerated material formation.

[0028] Optionally, the waste collection box is equipped with a filter screen, and the bottom of the waste collection box is connected to a recovery pipe, with the end of the recovery pipe away from the waste collection box connected to the reactor body.

[0029] By adopting the above technical solution, when the agglomerated material moves into the waste collection box, it will carry some normal material into the waste collection box. After entering the waste collection box, the normal material flows through the filter screen and returns to the reactor body through the recovery pipe to continue emulsification.

[0030] Optionally, an anti-corrosion layer is provided on the inner wall of the reactor body, and the anti-corrosion layer is made of titanium.

[0031] By adopting the above technical solution, titanium is used to make the anti-corrosion layer, which plays a role in corrosion resistance, high temperature resistance, wear resistance and non-toxicity, thereby improving the service life and safety of the reactor.

[0032] In summary, this application includes at least one of the following beneficial effects:

[0033] 1. In this application, a heat exchange jacket is provided outside the reactor body, and heating plates are provided on the stirring shaft. When it is necessary to heat the material inside the reactor body, the heat exchange jacket and heating plates are used to heat the inside and outside of the reactor body at the same time. The heating uniformity of the material inside the reactor body is improved by mixing the inside and outside heating.

[0034] 2. In this application, a heat exchange tank is provided on the reactor body, and an auxiliary heat exchange cavity is formed between the heat exchange tank and the sealing plate. The heat exchange medium is filled into the auxiliary heat exchange cavity from the temperature control inlet. The heat exchange medium moves to the middle of the reactor body through the auxiliary heat exchange cavity and exchanges heat with the material located in the middle of the reactor body, thereby further improving the heating uniformity of the material in the reactor body.

[0035] 3. In this application, the heat exchange tank is provided with multiple flow pipes, and both ends of the flow pipes are connected to the inside of the reactor body. When the material inside the reactor body passes through the flow pipes under the action of the stirring shaft, the multiple flow pipes shear the material to improve the mixing effect of the material inside the reactor body. Attached Figure Description

[0036] Figure 1 This is a schematic diagram of the overall structure of a pharmaceutical emulsification reactor according to Embodiment 1 of this application;

[0037] Figure 2 This is a cross-sectional view of a pharmaceutical emulsification reactor according to Embodiment 1 of this application;

[0038] Figure 3 This is a schematic diagram of the overall structure of a pharmaceutical emulsification reactor according to Embodiment 2 of this application;

[0039] Figure 4 This is a cross-sectional view of a pharmaceutical emulsification reactor according to Embodiment 2 of this application;

[0040] Figure 5 This is a schematic diagram of the filter plate structure of Embodiment 2 of this application.

[0041] Explanation of reference numerals in the attached drawings: 1. Reactor body; 11. Reactor body; 111. Discharge pipe; 12. Reactor cover; 121. Feed pipe; 122. Heat exchange shell; 1221. Heat exchange tube; 1222. Heat exchange tube array; 123. Heat exchange jacket; 124. Insulation shell; 125. Insulation jacket; 13. Heat exchange tank; 14. Sealing plate; 141. Air inlet pipe; 142. Exhaust pipe; 15. Auxiliary heat exchange chamber; 16. Opening and closing plate; 17. Opening and closing component; 2. Stirring assembly; 21. Stirring shaft; 211. First rotating shaft; 212. Second rotating shaft; 213. Linkage rotating shaft; 22. First driving component; 23. Heating plate; 24. Stirring blade; 3. First guide plate; 4. Flow pipe; 5. Filter plate; 51. Clearance notch; 6. Second driving component; 7. Waste collection box; 71. Observation window; 73. Third driving component; 74. Filter screen; 75. Recovery pipe; 76. Waste inlet; 8. Waste pusher plate; 9. Frame; 10. Second guide plate. Detailed Implementation

[0042] The following is in conjunction with the appendix Figure 1-5 This application will be described in further detail.

[0043] Example 1:

[0044] Embodiment 1 of this application provides a pharmaceutical emulsification reactor.

[0045] refer to Figure 1 A pharmaceutical emulsification reactor includes a reactor body 1 and a stirring assembly 2 mounted on the reactor body 1. The reactor body 1 includes a detachably connected vessel body 11 and a vessel cover 12. A connecting flange is integrally formed at one end of the vessel body 11 near the vessel cover 12, and a connecting flange is also integrally formed at one end of the vessel cover 12 near the vessel body 11. The two connecting flanges are connected by bolts, thus achieving a detachable connection of the vessel cover 12 to the vessel body 11. A feed inlet is provided on the vessel cover 12, connected to a feed pipe 121. An opening / closing plate 16 is detachably connected to the end of an air inlet pipe 141 away from the vessel cover 12 to control the opening or closing of the feed inlet. A discharge outlet is provided at the bottom of the vessel body 11, connected to a discharge pipe 111. An opening / closing element 17 is installed on the air inlet pipe 141 to control the opening or closing of the discharge outlet.

[0046] Both the lid 12 and the inner wall of the vessel body 11 are fixed with anti-corrosion layers, and the anti-corrosion layers are made of titanium.

[0047] refer to Figure 2A heat exchange shell 122 is fitted over the vessel body 11 and fixed to the outer wall of the vessel body 11. A heat exchange interlayer 123 is formed between the inner wall of the heat exchange shell 122 and the outer wall of the vessel body 11. The heat exchange shell 122 has a heat exchange inlet and a heat exchange outlet. The heat exchange inlet is located at the end of the heat exchange shell 122 near the vessel cover 12, and the heat exchange outlet is located at the bottom of the heat exchange shell 122. A heat exchange tube 1221 is connected to the heat exchange inlet, and a heat exchange manifold 1222 is connected to the heat exchange outlet. A first guide plate 3 is provided inside the heat exchange interlayer 123 and is spirally wound around the outer wall of the vessel body 11. One side of the first guide plate 3 is fixedly connected to the outer wall of the vessel body 11, and the other side of the first guide plate 3 is fixedly connected to the inner wall of the heat exchange shell 122. The first guide plate 3 is configured to form a spiral channel within the heat exchange jacket 123, with one end of the spiral channel connected to the heat exchange outlet and the other end connected to the heat exchange outlet.

[0048] When it is necessary to heat the material inside the reactor body 1, high-temperature steam is introduced into the heat exchange jacket 123 through the heat exchange tube 1221. Under the action of the first guide plate 3, the high-temperature steam moves along the spiral channel from top to bottom into the heat exchange jacket 123 to fill the entire heat exchange jacket 123, thereby heating the material inside the reactor body 1.

[0049] refer to Figure 2 An insulation shell 124 is fitted over and fixedly connected to the heat exchange shell 122. An insulation interlayer 125 is formed between the inner wall of the insulation shell 124 and the outer wall of the heat exchange shell 122, reducing heat loss and improving the stability of the reaction temperature inside the reactor body 1, thereby ensuring the smooth progress of the reaction. In other methods, insulation material can also be filled into the insulation interlayer 125.

[0050] refer to Figure 2 The stirring assembly 2 includes a first driving component 22 and a stirring shaft 21 rotatably disposed within the reactor body 1. A frame 9 is fixed on the outer wall of the reactor cover 12, and a first driving source is fixed within the frame 9. One end of the stirring shaft 21 passes through the reactor cover 12 and enters the frame 9. A reducer is connected between the stirring shaft 21 and the first driving component 22. In this embodiment, the first driving component 22 is specifically configured as a motor. A stirring blade 24 is fixed to the end of the stirring shaft 21 away from the first driving source, and a heating element 23 is also fixed on the stirring shaft 21. The number of heating elements 23 can be set according to specific needs. In this embodiment, two heating elements 23 are provided. When high-temperature steam is introduced into the phase heat exchange jacket 123, the heating elements 23 need to be turned on simultaneously to heat the interior of the reactor body 1, thereby improving the heating uniformity of the material inside the reactor body 1.

[0051] The implementation principle of a pharmaceutical emulsification reactor according to an embodiment of this application is as follows: The opening and closing plate 16 is opened, and the materials to be mixed are added into the reactor body 11 through the feed pipe 121. After the materials are added, the opening and closing plate 16 is closed. The motor is started to drive the stirring shaft 21 to rotate, stirring the materials inside the reactor body 11. During the stirring process, high-temperature steam is introduced into the heat exchange jacket 123 through the heat exchange pipe 1221, and at the same time, the heating element 23 is activated to heat the interior of the reactor body 11.

[0052] Example 2:

[0053] Embodiment 2 of this application provides a pharmaceutical emulsification reactor.

[0054] refer to Figure 3 and Figure 4 The difference between Embodiment 2 and Embodiment 1 is that in this embodiment, the discharge port is located on the side wall of the vessel body 11. Correspondingly, one end of the discharge pipe 111 is connected to the discharge port, and the other end passes through the heat exchange shell 122 and the insulation shell 124 in sequence. The bottom of the vessel body 11 is concave upward, and a heat exchange tank 13 is integrally formed therein, with the heat exchange tank 13 located in the middle of the vessel body 11. A sealing plate 14 is fixed at the opening of the heat exchange tank 13, and an auxiliary heat exchange cavity 15 is formed between the sealing plate 14 and the inner side wall of the heat exchange tank 13. A second guide plate 10 is provided in the auxiliary heat exchange cavity 15. One end of the second guide plate 10 is fixedly connected to the sealing plate 14; the other end is located near the bottom of the heat exchange tank 13, and both sides of the second guide plate 10 are attached to and fixedly connected to the inner side wall of the heat exchange tank 13. The sealing plate 14 has a temperature control inlet and a temperature control outlet, which are located on both sides of the second guide plate 10. The temperature control inlet is connected to the air inlet pipe 141, and the temperature control outlet is connected to the exhaust pipe 142.

[0055] refer to Figure 4 When it is necessary to heat the material inside the reactor body 1, high-temperature steam can be introduced into the auxiliary heat exchange chamber 15 through the air inlet pipe 141. After heat exchange, the steam is discharged through the exhaust pipe 142. This further improves the heating uniformity of the material inside the reactor body 1.

[0056] refer to Figure 4 A flow pipe 4 is fixed inside the heat exchange chamber, and multiple flow pipes 4 are arranged at equal intervals along the vertical direction. Specifically, the flow pipe 4 is configured as an upwardly bent pipe, and both ends of the flow pipe 4 pass through the side wall of the heat exchange tank 13 and are connected to the inside of the reactor body 11. When the material inside the reactor body 1 passes through the flow pipe 4 under the action of the stirring shaft 21, the multiple flow pipes 4 shear the material to improve the mixing effect of the material inside the reactor body 1.

[0057] refer to Figure 4In this embodiment, the stirring shaft 21 includes a first rotating shaft 211, a second rotating shaft 212, and a linkage rotating shaft 213 connecting the first rotating shaft 211 and the second rotating shaft 212. Both the first rotating shaft 211 and the second rotating shaft 212 are vertically arranged, with one end of the first rotating shaft 211 connected to a reducer. The linkage rotating shaft 213 is perpendicular to the first rotating shaft 211. The heating element 23 and the stirring blade 24 are located on the second rotating shaft 212. Furthermore, in this embodiment, two second rotating shafts 212 are spaced apart, and the dimensions of the heating element 23 and the stirring blade 24 are smaller than those in Embodiment 1.

[0058] refer to Figure 4 and Figure 5 A filter plate 5 is slidably disposed inside the vessel body 11. The filter plate 5 is specifically annular, and its inner diameter is the same as the outer diameter of the heat exchange tank 13, allowing the filter plate 5 to pass through the heat exchange tank 13. The filter plate 5 also has a clearance notch 51 for the stirring shaft 21 to pass through. A second driving component 6 is disposed below the vessel body 11. The second driving component 6 is specifically configured as a lifting cylinder, and the piston rod of the lifting cylinder passes through the vessel body 11 and is fixedly connected to the filter plate 5.

[0059] refer to Figure 3 and Figure 4 A waste collection box 7 is provided on the side of the vessel body 11 near the vessel lid 12, and the waste collection box 7 is fixed to the outer wall of the vessel body 11. A waste inlet 76 is opened at the end of the waste collection box 7 near the vessel body 11, and the waste inlet 76 is connected to the interior of the vessel body 11. A filter screen 74 is also fixed inside the waste collection box 7. An installation port is opened on the side of the waste collection box 7 away from the vessel body 11, and an observation window 71 is fixed in the installation port. A recovery pipe 75 is connected to the bottom of the waste collection box 7, and the end of the recovery pipe 75 away from the waste recovery box is connected to the vessel body 11.

[0060] refer to Figure 4 A waste pusher plate 8 is slidably disposed inside the vessel body 11, and the waste pusher plate 8 is positioned opposite to the waste inlet 76. A third driving component 73 is fixed to the outside of the vessel body 11. The third driving component 73 is specifically configured as a pushing cylinder, and the piston rod of the pushing cylinder passes through the side wall of the vessel body 11 and is fixedly connected to the waste pusher plate 8. In this embodiment, two waste pushers 8 are spaced apart, and the third driving component 73 is configured in a one-to-one correspondence with the waste pusher plate 8. The distance between the two waste pushers 8 is greater than or equal to the diameter of the first rotating shaft 211, allowing the waste pusher plate 8 to slide smoothly inside the vessel body 11. In this embodiment, the distance between the two waste pushers 8 is equal to the diameter of the first rotating shaft 211.

[0061] refer to Figure 4After the motor-driven stirring shaft 21 stirs within the reactor body 11 for a period of time, the first motor is turned off, aligning the stirring blades 24 on the stirring shaft 21 with the clearance notch 51 on the filter plate 5. Then, the lifting cylinder is activated, driving the filter plate 5 to move vertically upwards. As the filter plate 5 moves, the agglomerated material formed within the reactor body 11 falls onto the filter plate 5 and moves with it. When the filter plate 5 reaches the waste inlet 76, the pushing cylinder is activated to drive the waste pushing plate 8 towards the waste inlet 76, pushing the agglomerated material on the filter plate 5 into the waste collection box 7. The operator can observe the collection of agglomerated material in the waste collection box 7 through the observation window 71 and adjust the emulsification environment of the material within the reactor body 1 in a timely manner based on the agglomerated material formation.

[0062] The above are all preferred embodiments of this application, and are not intended to limit the scope of protection of this application. Therefore, all equivalent changes made in accordance with the structure, shape and principle of this application should be covered within the scope of protection of this application.

Claims

1. A pharmaceutical emulsifying reactor, characterized in that, include: The reactor body (1) is provided with a feed inlet and a discharge outlet, both of which can be opened or closed. The stirring assembly (2) includes a stirring shaft (21) and a first driving member (22) for driving the stirring shaft (21) to rotate. The first driving member (22) is disposed outside the reactor body (1), and the stirring shaft (21) is rotatably disposed inside the reactor body (1). A heating element (23) is disposed on the stirring shaft (21). A heat exchange shell (122) is provided outside the reactor body (1). A heat exchange jacket (123) is formed between the inner side wall of the heat exchange shell (122) and the outer side wall of the reactor body (1). A heat exchange inlet and a heat exchange outlet are provided on the heat exchange shell (122). A heat exchange tank (13) is provided on the reactor body (1), and the heat exchange tank (13) is located in the middle of the reactor body (1); A sealing plate (14) is provided at the opening at the bottom of the heat exchange tank (13), and an auxiliary heat exchange cavity (15) is formed between the sealing plate (14) and the heat exchange tank (13). A temperature control inlet and a temperature control outlet are provided on the sealing plate (14). The auxiliary heat exchange chamber (15) is provided with a second guide plate (10), one end of which is fixedly connected to the sealing plate (14); the other end is located near the bottom wall of the heat exchange tank (13), and the temperature control inlet and the temperature control outlet are located on both sides of the second guide plate (10). The heat exchange tank (13) is provided with multiple flow pipes (4), both ends of which are connected to the interior of the reactor body (1), and the flow pipes (4) are bent upwards. A filter plate (5) is slidably disposed inside the reactor body (1), and a second driving member (6) is disposed outside the reactor body (1) for driving the filter plate (5) to slide in the vertical direction. The filter plate (5) is annular, and the inner diameter of the filter plate (5) is the same as the outer diameter of the heat exchange tank (13), so that the filter plate (5) can pass through the heat exchange tank (13). The filter plate (5) is also provided with a clearance notch (51) for the stirring shaft (21) to pass through.

2. The pharmaceutical emulsifying reactor according to claim 1, characterized in that, The heat exchange jacket (123) is provided with a first guide plate (3), which is spirally wrapped around the outer wall of the reactor body (1). The heat exchange inlet and the heat exchange outlet are located at both ends of the heat exchange shell (122).

3. The pharmaceutical emulsifying reactor according to claim 1, characterized in that, The heat exchange jacket (123) is covered with an insulation shell (124), and an insulation jacket (125) is formed between the inner wall of the insulation shell (124) and the inner wall of the insulation shell (124).

4. The pharmaceutical emulsifying reactor according to claim 1, characterized in that, A waste collection box (7) is connected to one side of the reactor body (1), and an observation window (71) is provided on the waste collection box (7); a waste pusher plate (8) is slidably arranged inside the reactor body (1), and a third driving component (73) is provided on the reactor body (1) for driving the waste pusher plate (8) to slide.

5. A pharmaceutical emulsifying reactor according to claim 4, characterized in that, The waste collection box (7) is equipped with a filter screen (74), and the bottom of the waste collection box (7) is connected to a recovery pipe (75). The end of the recovery pipe (75) away from the waste collection box (7) is connected to the reactor body (1).

6. The pharmaceutical emulsifying reactor according to claim 1, characterized in that, The inner wall of the reactor body (1) is provided with an anti-corrosion layer, which is made of titanium.

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