A composition containing bromopropylate and dinotefuran, and a preparation method and application thereof

Abstract

The application relates to the technical field of insecticidal compositions. The application discloses a composition containing chlorantraniliprole and dinotefuran as well as a preparation method and application thereof. Raw material composition of the composition comprises chlorantraniliprole, dinotefuran, d-cycloprothrin, d-phenothrin, azocyclotin, polyethylene diamine, sophoraflavescens aiton, grapefruit peel extract, capsicum annuum extract, plant essential oil and solvent. The preparation method comprises the following steps: S1, mixing chlorantraniliprole, dinotefuran, d-cycloprothrin and azocyclotin, and stirring; S2, adding polyethylene diamine and solvent, and stirring and mixing; S3, adding sophoraflavescens aiton, grapefruit peel extract, capsicum annuum extract and plant essential oil, stirring and mixing, and preparing the composition. The application also discloses application of the composition in the field of pest control. The prepared composition containing chlorantraniliprole and dinotefuran can effectively improve the pest control effect and has a long effective duration.

Description

Technical Field

[0001] This application relates to the field of insecticidal composition technology, and in particular to a composition containing bromocyanamide and dinotefuran, its preparation method and application. Background Technology

[0002] Mosquitoes, flies, and cockroaches are three major pests in human life, carrying and transmitting various diseases. For example, mosquitoes are vectors for diseases such as malaria, dengue fever, and Japanese encephalitis; flies can carry and transmit various pathogens; and cockroaches themselves carry 40-50 kinds of bacteria pathogenic to vertebrates, such as Escherichia coli, Shigella, and Yersinia pestis, as well as eggs of various worms such as roundworms, hookworms, beef tapeworms, pinworms, and whipworms, posing a significant threat to human health. The secretions and excrement of mosquitoes, flies, and cockroaches can cause allergic reactions in humans, such as rashes and asthma. The presence of these pests also disrupts human life, such as through bites and food contamination. Therefore, effective control of mosquitoes, flies, and cockroaches is of great practical significance for human health and well-being.

[0003] Currently, chemical control is the most effective, inexpensive, and convenient method for controlling mosquitoes, flies, and cockroaches. Among chemical insecticides, bromocyanamide and dinotefuran are characterized by high efficiency, broad spectrum, and low toxicity, making them very safe for crops, humans, livestock, and the environment.

[0004] However, cyantraniliprole is highly resistant to pests, requiring continuously increasing dosages to maintain its effectiveness, and it tends to lose its effectiveness over time, reducing its efficacy. Fipronil, on the other hand, has a shorter residual effect, requiring frequent application to maintain its control.

[0005] Therefore, in view of the problems existing in the control of pests by broflanilide and fipronil, there is an urgent need to develop a composition containing broflanilide and fipronil that can effectively improve the control effect and has a long-lasting effect. Summary of the Invention

[0006] In order to solve at least one of the above-mentioned technical problems, and to develop a composition containing bromocyanamide and fipronil that can effectively improve the pest control effect and have a long-lasting effect, this application provides a composition containing bromocyanamide and fipronil, its preparation method and application.

[0007] On the one hand, the composition containing bromocyanamide and fipronil provided in this application, by weight, comprises the following raw materials: 5-10 parts bromocyanamide, 10-15 parts fipronil, 1-2 parts dextromethorphan, 0.3-1 parts dextromethorphan, 1-1.5 parts azone, 5-10 parts polyethylene glycol, 0.5-1 parts matrine, 0.5-1 parts grapefruit peel extract, 0.5-1 parts capsicum extract, 0.5-1 parts plant essential oil, and 80-100 parts solvent.

[0008] By adopting the above technical solution, this application uses specific raw materials and proportions to prepare a composition containing bromocyanamide and fipronil, which can effectively improve the pest control effect, has a long-lasting effect, and can also absorb carbon dioxide, reducing the carbon dioxide concentration in the environment. The composition containing bromocyanamide and fipronil of this application can knock down mosquitoes, flies, and cockroaches in a short time and prevent them from reviving, thereby achieving the purpose of pest control.

[0009] In this application, bromocyanamide and dinotefuran are the main components of the composition, which are characterized by high efficiency, broad spectrum, and low toxicity, and have control effects on a variety of pests. The addition of d-cypermethrin and d-fenofibrate in this application can affect the nervous system of mosquitoes, flies, and cockroaches, leading to paralysis and death. Azone, as a synergist, can increase the activity of the composition and promote its penetration into the insect body surface, thereby improving the control effect. Polyethylene diamine can enhance the adhesion and penetration ability of the composition, improve its stability and effectiveness, and can also absorb carbon dioxide, reducing the carbon dioxide concentration in the environment. Matrine, grapefruit peel extract, chili extract, and plant essential oils are all natural plant-derived components that can enhance the insecticidal activity of the composition while being environmentally friendly.

[0010] Optionally, the composition containing bromocyanamide and fipronil, by weight, comprises the following raw materials: 6-8 parts bromocyanamide, 12-13 parts fipronil, 1.5-2 parts d-cypermethrin, 0.5-0.8 parts d-phenylephrine, 1.3-1.5 parts azone, 6-8 parts polyethylene glycol, 0.8-1 part matrine, 0.8-1 part grapefruit peel extract, 0.8-1 part capsicum extract, 0.8-1 part plant essential oil, and 85-95 parts solvent.

[0011] Optionally, the composition containing bromocyanamide and fipronil, by weight, comprises the following raw materials: 7 parts bromocyanamide, 12.6 parts fipronil, 1.8 parts dextromethorphan, 0.7 parts dextromethorphan, 1.4 parts azone, 7 parts polyethylene glycol, 0.9 parts matrine, 1 part grapefruit peel extract, 0.9 parts capsicum extract, 0.9 parts plant essential oil, and 90 parts solvent.

[0012] Optionally, the weight ratio of the bromocyanamide to the dextromethorphan is 8 to 12:1.

[0013] By adopting the above technical solution, the combined use of bromocyanamide and dextromethorphan in this application can enhance the control effect on pests while reducing the development of pesticide resistance. The appropriate weight ratio allows the two components to exert their optimal effect.

[0014] Optionally, the weight ratio of the bromocyanamide to the dextromethorphan is 10:1.

[0015] Optionally, the molecular weight of the polyethylene glycol is 10,000 to 100,000.

[0016] By adopting the above technical solution, the molecular weight range of the polyethylene glycol in this application can achieve a balance between permeability and durability. If the molecular weight is lower, its permeability is better, but its durability is poorer, and it may need to be applied repeatedly; if the molecular weight is higher, its durability is better, but its permeability is poorer, and it takes longer to achieve the desired effect.

[0017] Optionally, the molecular weight of the polyethylene glycol is 50,000 to 80,000.

[0018] Optionally, the weight ratio of the fipronil to the matrine is 13-15:1.

[0019] By employing the above-mentioned technical solution, this application combines fipronil and matrine, thereby improving the activity of the composition, enhancing the control effect on pests, and reducing the development of pest resistance. The appropriate weight ratio of fipronil and matrine in this application achieves better pest control, allowing both to exert their optimal effect.

[0020] Optionally, the weight ratio of the fipronil to the matrine is 14:1.

[0021] Optionally, the plant essential oil is selected from at least one of tea tree oil, peppermint oil, chamomile oil, and eucalyptus oil.

[0022] By adopting the above technical solution, the addition of plant essential oils in this application can improve permeability, increase the insecticidal effect of the composition, and inhibit the development of pesticide resistance in pests.

[0023] Optionally, the plant essential oil is chamomile essential oil and eucalyptus essential oil.

[0024] By adopting the above technical solution, the addition of chamomile essential oil and eucalyptus essential oil together can enhance the insecticidal effect of the composition and improve the control effect.

[0025] Optionally, the solvent is selected from at least one of methanol, ethanol, ethyl acetate, and ethyl ketone.

[0026] By adopting the above technical solution, the addition of solvent in this application can dissolve the active ingredients, improve the stability of the composition, and extend its service life.

[0027] Secondly, this application provides a method for preparing the above-mentioned composition containing bromocyanamide and dinotefuran, comprising the following steps:

[0028] S1. Mix the bromocyanamide, fipronil, dextromethorphan, dextromethorphan, and azone, and stir for 10-30 minutes to obtain mixture A.

[0029] S2. Add the mixture A and the polyethylene glycol to the solvent and stir for 30-60 minutes to obtain mixture B; S3. Add the matrine, grapefruit peel extract, chili extract and plant essential oil to mixture B and stir for 60-90 minutes to obtain the composition containing bromocyanamide and fipronil.

[0030] By adopting the above technical solution, this application uses a three-step mixing process to ensure that all components are fully mixed and dissolved to achieve the best effect, thereby improving the uniformity and stability of the composition. The resulting composition containing bromocyanamide and fipronil has good stability, effectively improves the pest control effect, and has a long-lasting effect.

[0031] Optionally, in step S1, the stirring speed is 500-700 r / min; in step S2, the stirring speed is 600-700 r / min; and in step S3, the stirring speed is 600-800 r / min.

[0032] By adopting the above technical solution, this application uses a specific stirring speed to ensure appropriate mixing and dissolution rates at different stages, resulting in a uniform and stable composition. If the stirring speed is too slow, the components may not mix evenly, affecting the composition's effectiveness; if the stirring speed is too fast, a large amount of foam may be generated, affecting the composition's stability and performance.

[0033] Thirdly, this application provides the application of the above-mentioned composition containing bromocyanamide and dinotefuran in the field of pest control.

[0034] Optionally, the composition containing bromocyanamide and dinotefuran can be used in the control of mosquitoes, flies, and cockroaches.

[0035] By adopting the above technical solution, the composition containing bromocyanamide and fipronil obtained in this application can be widely used in the field of pest control, especially in controlling mosquitoes, flies, and cockroaches. This is of great significance for protecting public health and improving the quality of life.

[0036] In summary, the present invention has at least one of the following beneficial technical effects:

[0037] 1. This application uses specific raw materials and proportions to prepare a composition containing bromocyanamide and fipronil, which can effectively improve the pest control effect, has a long-lasting effect, and can also absorb carbon dioxide and reduce the concentration of carbon dioxide in the environment.

[0038] 2. The composition of this application containing bromocyanamide and fipronil can knock down mosquitoes, flies, and cockroaches in a short period of time and prevent them from reviving, thereby achieving the purpose of prevention and control.

[0039] 3. The addition of polyethylene glycol in this application can enhance the adhesion and penetration ability of the composition, improve the stability and performance of the composition, and also absorb carbon dioxide, reducing the concentration of carbon dioxide in the environment.

[0040] 4. The preparation method of this application involves three mixing steps to ensure that all components are fully mixed and dissolved to achieve the best effect, thereby improving the uniformity and stability of the composition. The resulting composition containing bromocyanamide and fipronil has good stability, effectively improves the pest control effect, and has a long-lasting effect. Detailed Implementation

[0041] The present application will be further described in detail below with reference to the embodiments.

[0042] This application designs a composition containing bromocyanamide and fipronil. By weight, its raw material composition includes: 5-10 parts bromocyanamide, 10-15 parts fipronil, 1-2 parts dextromethorphan, 0.3-1 parts dextromethorphan, 1-1.5 parts azone, 5-10 parts polyethylene glycol, 0.5-1 parts matrine, 0.5-1 parts grapefruit peel extract, 0.5-1 parts capsicum extract, 0.5-1 parts plant essential oil, and 80-100 parts solvent.

[0043] The composition containing bromocyanamide and dinotefuran of this application is prepared by the following method, including the following steps:

[0044] S1. Mix the bromocyanamide, fipronil, dextromethorphan, dextromethorphan, and azone, and stir for 10-30 minutes to obtain mixture A.

[0045] S2. Add the mixture A and the polyethylene glycol to the solvent and stir for 30-60 minutes to obtain mixture B; S3. Add the matrine, grapefruit peel extract, chili extract and plant essential oil to mixture B and stir for 60-90 minutes to obtain the composition containing bromocyanamide and fipronil.

[0046] The composition containing bromocyanamide and dinotefuran of this application can be used in the field of pest control.

[0047] The applicant has designed the technical solution to address the problems of cyantraniliprole and dinotefuran in pest control, namely, the ease with which pests develop resistance, short residual effect, and insufficient control efficacy.

[0048] This application first discloses a composition containing brofenoxam and dinotefuran, comprising: brofenoxam, dinotefuran, d-methoxyfenozide, d-phenylmethoxyfenozide, azone, polyethylene glycol, matrine, grapefruit peel extract, chili extract, plant essential oil, and solvent. It can effectively improve pest control efficacy, has a long-lasting effect, and can also absorb carbon dioxide, reducing the concentration of carbon dioxide in the environment.

[0049] Secondly, the preparation method of the composition containing bromocyanamide and fipronil used in this application involves mixing in three steps to ensure that each component is fully mixed and dissolved, thereby achieving the best effect, improving the uniformity and stability of the composition, and thus enhancing the control effect.

[0050] The raw materials used in this application are as follows:

[0051] Bromnipotent: CAS: 736994-63-1.

[0052] Fipronil: CAS: 165252-70-0.

[0053] Dextromethorphan: CAS: 1166-46-7.

[0054] Dextrorotatory cypermethrin: CAS: 39515-40-7.

[0055] Azone: CAS: 59227-89-3.

[0056] Matrine: CAS: 16837-52-8.

[0057] Grapefruit peel extract: purity, 99%.

[0058] Capsicum extract: CAS: 84625-29-6.

[0059] Tea tree oil: CAS: 68647-73-4.

[0060] Peppermint essential oil: CAS: 68917-18-0.

[0061] Chamomile essential oil: CAS: 8002-66-2.

[0062] Eucalyptus essential oil: CAS: 8000-48-4.

[0063] Methanol: CAS: 67-56-1.

[0064] Ethanol: CAS: 64-17-5.

[0065] Ethyl acetate: CAS: 141-78-6.

[0066] Ethyl ketone: CAS: 67-64-1. Specific Implementation

[0068] Examples 1-5

[0069] Example 1

[0070] This embodiment provides a composition containing bromocyanamide and fipronil. By weight, its raw material composition includes: 5 parts bromocyanamide, 15 parts fipronil, 1 part d-cypermethrin, 1 part d-phenylephrine, 1 part azone, 5 parts polyethylene glycol, 1 part matrine, 1.5 parts grapefruit peel extract, 0.5 parts capsicum extract, 0.5 parts tea tree oil, and 80 parts methanol. The polyethylene glycol has a molecular weight of 10,000.

[0071] The preparation method includes the following steps:

[0072] S1. Mix the bromocyanamide, fipronil, dextromethorphan, dextromethorphan, and azone, and stir at a stirring speed of 600 r / min for 20 min to obtain mixture A.

[0073] S2. Add the mixture A and the polyethylene glycol to the methanol and stir at a stirring speed of 650 r / min for 45 min to obtain mixture B;

[0074] S3. Add the matrine, grapefruit peel extract, chili extract and tea tree oil to the mixture B, and stir at a stirring speed of 700 r / min for 75 min to obtain the composition containing bromocyanamide and fipronil.

[0075] Example 2

[0076] This embodiment provides a composition containing bromocyanamide and fipronil. By weight, its raw material composition includes: 8 parts bromocyanamide, 12 parts fipronil, 1.5 parts d-cypermethrin, 0.5 parts d-phenylephrine, 1.3 parts azone, 6 parts polyethylene glycol, 0.8 parts matrine, 1.2 parts grapefruit peel extract, 0.8 parts capsicum extract, 1 part tea tree oil, and 85 parts methanol. The polyethylene glycol has a molecular weight of 10,000.

[0077] The preparation method includes the following steps:

[0078] S1. Mix the bromocyanamide, fipronil, dextromethorphan, dextromethorphan, and azone, and stir at a stirring speed of 600 r / min for 20 min to obtain mixture A.

[0079] S2. Add the mixture A and the polyethylene glycol to the methanol and stir at a stirring speed of 650 r / min for 45 min to obtain mixture B;

[0080] S3. Add the matrine, grapefruit peel extract, chili extract and tea tree oil to the mixture B, and stir at a stirring speed of 700 r / min for 75 min to obtain the composition containing bromocyanamide and fipronil.

[0081] Example 3

[0082] This embodiment provides a composition containing brofenoxam and fipronil. By weight, its raw material composition includes: 7 parts brofenoxam, 12.6 parts fipronil, 1.8 parts d-cypermethrin, 0.7 parts d-phenylephrine, 1.4 parts azone, 7 parts polyethylene glycol, 0.9 parts matrine, 1 part grapefruit peel extract, 0.9 parts capsicum extract, 0.9 parts tea tree oil, and 90 parts methanol. The polyethylene glycol has a molecular weight of 10,000.

[0083] The preparation method includes the following steps:

[0084] S1. Mix the bromocyanamide, fipronil, dextromethorphan, dextromethorphan, and azone, and stir at a stirring speed of 600 r / min for 20 min to obtain mixture A.

[0085] S2. Add the mixture A and the polyethylene glycol to the methanol and stir at a stirring speed of 650 r / min for 45 min to obtain mixture B;

[0086] S3. Add the matrine, grapefruit peel extract, chili extract and tea tree oil to the mixture B, and stir at a stirring speed of 700 r / min for 75 min to obtain the composition containing bromocyanamide and fipronil.

[0087] Example 4

[0088] This embodiment provides a composition containing bromocyanamide and fipronil. By weight, its raw material composition includes: 6 parts bromocyanamide, 13 parts fipronil, 2 parts d-cypermethrin, 0.8 parts d-phenylephrine, 1.5 parts azone, 8 parts polyethylene glycol, 1 part matrine, 0.8 parts grapefruit peel extract, 1 part capsicum extract, 0.8 parts tea tree oil, and 95 parts methanol. The polyethylene glycol has a molecular weight of 10,000.

[0089] The preparation method includes the following steps:

[0090] S1. Mix the bromocyanamide, fipronil, dextromethorphan, dextromethorphan, and azone, and stir at a stirring speed of 600 r / min for 20 min to obtain mixture A.

[0091] S2. Add the mixture A and the polyethylene glycol to the methanol and stir at a stirring speed of 650 r / min for 45 min to obtain mixture B;

[0092] S3. Add the matrine, grapefruit peel extract, chili extract and tea tree oil to the mixture B, and stir at a stirring speed of 700 r / min for 75 min to obtain the composition containing bromocyanamide and fipronil.

[0093] Example 5

[0094] This embodiment provides a composition containing brofenoxam and fipronil. By weight, its raw material composition includes: 10 parts brofenoxam, 10 parts fipronil, 2 parts d-cypermethrin, 0.3 parts d-phenylephrine, 1.5 parts azone, 10 parts polyethylene glycol, 0.5 parts matrine, 0.5 parts grapefruit peel extract, 1 part capsicum extract, 1 part tea tree oil, and 100 parts methanol. The polyethylene glycol has a molecular weight of 10,000.

[0095] The preparation method includes the following steps:

[0096] S1. Mix the bromocyanamide, fipronil, dextromethorphan, dextromethorphan, and azone, and stir at a stirring speed of 500-700 r / min for 10-30 min to obtain mixture A.

[0097] S2. Add the mixture A and the polyethylene glycol to the methanol, and stir and mix at a stirring speed of 600-700 r / min for 30-60 min to obtain mixture B;

[0098] S3. Add the matrine, grapefruit peel extract, chili extract and tea tree oil to the mixture B, and stir at a stirring speed of 600-800 r / min for 60-90 min to obtain the composition containing bromocyanamide and fipronil.

[0099] Comparative Examples 1-5

[0100] Comparative Example 1

[0101] The difference between Comparative Example 1 and Example 3 is that Comparative Example 1 did not contain d-aminopyrethrin and d-phenylephrine.

[0102] Comparative Example 2

[0103] The difference between Comparative Example 2 and Example 3 is that Polyethylene Diamine was not added to Comparative Example 2.

[0104] Comparative Example 3

[0105] The difference between Comparative Example 3 and Example 3 is that Comparative Example 3 did not contain matrine.

[0106] Comparative Example 4

[0107] The difference between Comparative Example 4 and Example 3 is that Comparative Example 4 did not include grapefruit peel extract.

[0108] Comparative Example 5

[0109] The difference between Comparative Example 5 and Example 3 is that the preparation method in Comparative Example 5 is as follows: all raw materials are mixed and stirred at a stirring speed of 700 r / min for 120 min.

[0110] Experimental testing

[0111] Testing items and testing methods

[0112] Carbon dioxide absorption detection: At room temperature, 20% carbon dioxide gas was continuously blown into 50 ml of a composition containing bromocyanamide and fipronil at a concentration of 900 μg / mL for 60 minutes, and the carbon dioxide concentration in the composition was measured to obtain the carbon dioxide absorption.

[0113] Experimental subjects: Culex pipiens pallens, female adult mosquitoes that did not feed on blood on the 3rd to 5th day after emergence; houseflies, adult mosquitoes on the 3rd to 4th day after emergence, half male and half female; German cockroaches, adult mosquitoes on the 10th to 15th day of age, half male and half female.

[0114] Test method: KT was tested according to GB / T 13917.2-2009 "Indoor Efficacy Test and Evaluation of Sanitary Insecticides for Pesticide Registration". 50 (Time required to knock down half of the test insects) and the 24-hour mortality rate of the test subjects.

[0115] The concentrations of the compositions containing bromocyanamide and dinotefuran prepared in Examples 1-5 and Comparative Examples 1-5 were diluted to 900 μg / mL, and KT was detected. 50 To determine the mortality rate of the test subjects, the compositions containing bromocyanamide and fipronil prepared in Examples 1-5 and Comparative Examples 1-5 were stored at room temperature for 60 days and then diluted to 900 μg / mL. The KT (knockout rate) of the German cockroach was then measured. 50 The mortality rate and test results are shown in Table 1.

[0116] Table 1

[0117]

[0118]

[0119] As shown in Table 1, the compositions containing bromocyanamide and dinotefuran prepared in Examples 1-5 exhibit significant control effects against mosquitoes, flies, and cockroaches, rapidly knocking them down and causing their death. Furthermore, after 60 days of storage at room temperature, KT... 50The minimal changes indicate that the compositions containing bromocyanamide and dinotefuran prepared in Examples 1-5 have a long duration of action. Among them, the composition containing bromocyanamide and dinotefuran prepared in Example 3 showed the best control effect against mosquitoes, flies, and cockroaches.

[0120] In Comparative Example 1, without the addition of d-cypermethrin and d-fenfluramide, the composition containing bromocyanamide and dinotefuran showed a significant decrease in control efficacy against mosquitoes, flies, and cockroaches. 50 The length was greatly increased, and the mortality rate was also reduced significantly.

[0121] In Comparative Example 2, without the addition of polyethylene glycol (PEG), the composition containing bromocyanamide and dinotefuran showed a decreased control efficacy against mosquitoes, flies, and cockroaches. Carbon dioxide uptake was measured in Examples 3 and 2; Example 3 showed an uptake of 20 g / L, while Comparative Example 2 showed an uptake of 5 g / L. This indicates that PEG can effectively increase carbon dioxide uptake.

[0122] Comparative Example 3 did not contain matrine, and Comparative Example 4 did not contain grapefruit peel extract. The control efficacy of the compositions containing bromocyanamide and fipronil against mosquitoes, flies, and cockroaches was also reduced.

[0123] In Comparative Example 5, the raw materials were not mixed in three steps, but all of them were mixed and stirred at the same time. The resulting composition containing bromocyanamide and fipronil showed a decrease in the control effect on mosquitoes, flies, and cockroaches. Moreover, the control effect decreased significantly after 60 days, indicating poor persistence. The inventors speculated that the uneven mixing of the components affected the stability of the composition.

[0124] Examples 6-20

[0125] Example 6

[0126] The difference between Example 6 and Example 3 is that in Example 6, the weight ratio of bromocyanamide to dextromethorphan is 8:1, and the total weight of bromocyanamide and dextromethorphan is 7.7 parts.

[0127] Example 7

[0128] The difference between Example 7 and Example 3 is that in Example 7, the weight ratio of bromocyanamide to dextromethorphan is 12:1, and the total weight of bromocyanamide and dextromethorphan is 7.7 parts.

[0129] Example 8

[0130] The difference between Example 8 and Example 3 is that in Example 8, the molecular weight of polyethylene diamine is 50,000.

[0131] Example 9

[0132] The difference between Example 9 and Example 3 is that in Example 9, the molecular weight of polyethylene diamine is 100,000.

[0133] Example 10

[0134] The difference between Example 10 and Example 3 is that in Example 10, the weight ratio of fipronil to matrine is 13:1, and the total weight of fipronil and matrine is 13.5 parts.

[0135] Example 11

[0136] The difference between Example 11 and Example 3 is that in Example 11, the weight ratio of fipronil to matrine is 15:1, and the total weight of fipronil and matrine is 13.5 parts.

[0137] Example 12

[0138] The difference between Example 12 and Example 8 is that in Example 12, 0.9 parts of tea tree oil were replaced with an equal amount of peppermint oil.

[0139] Example 13

[0140] The difference between Example 13 and Example 8 is that in Example 13, 0.9 parts of tea tree oil are replaced with 0.4 parts of chamomile oil and 0.5 parts of eucalyptus oil.

[0141] Example 14

[0142] The difference between Example 14 and Example 13 is that in Example 14, 90 parts of methanol are replaced with 30 parts of ethanol, 30 parts of ethyl acetate and 30 parts of acetone.

[0143] Example 15

[0144] The difference between Example 15 and Example 3 is that in step S1 of Example 15, the stirring speed is 500 r / min.

[0145] Example 16

[0146] The difference between Example 16 and Example 3 is that in step S1 of Example 16, the stirring speed is 700 r / min.

[0147] Example 17

[0148] The difference between Example 17 and Example 3 is that in step S2 of Example 17, the stirring speed is 600 r / min.

[0149] Example 18

[0150] The difference between Example 18 and Example 3 is that in step S2 of Example 18, the stirring speed is 700 r / min.

[0151] Example 19

[0152] The difference between Example 19 and Example 3 is that in step S3 of Example 19, the stirring speed is 600 r / min.

[0153] Example 20

[0154] The difference between Example 20 and Example 3 is that in step S3 of Example 20, the stirring speed is 800 r / min.

[0155] The concentrations of the compositions containing bromocyanamide and dinotefuran prepared in Examples 6-20 were diluted to 900 μg / mL, and KT was measured. 50 To determine the mortality rate of the test subjects, the compositions containing bromocyanamide and fipronil prepared in Examples 6-20 were stored at room temperature for 60 days and then diluted to 900 μg / mL. The KT (knockout rate) of the German cockroach was then measured. 50 The mortality rate and test results are shown in Table 2.

[0156] Table 2

[0157]

[0158] As can be seen from the test results in Table 2, the difference between Example 6, Example 7 and Example 3 lies in the different weight ratios of bromocyanamide and dextromethorphan. Among them, the composition containing bromocyanamide and fipronil prepared in Example 3 has the best control effect on mosquitoes, flies and cockroaches.

[0159] The difference between Examples 8, 9 and 3 lies in the molecular weight of the polyethylene glycol. Among them, the composition containing bromocyanamide and fipronil prepared in Example 8 has the best control effect on mosquitoes, flies and cockroaches.

[0160] The difference between Examples 10, 11 and 3 lies in the different weight ratios of fipronil and matrine. Among them, the composition containing bromocyanamide and fipronil prepared in Example 3 has the best control effect on mosquitoes, flies and cockroaches.

[0161] In Example 12, the tea tree oil in Example 8 was replaced with an equal amount of peppermint oil. The resulting composition containing bromocyanamide and fipronil showed little change in its control effect on mosquitoes, flies, and cockroaches compared to Example 8.

[0162] In Example 13, the tea tree oil in Example 8 was replaced with chamomile oil and eucalyptus oil. The resulting composition containing bromocyanamide and fipronil showed better control effects against mosquitoes, flies, and cockroaches than that in Example 8.

[0163] Example 14 replaced methanol in Example 13 with ethanol, ethyl acetate and acetone. The resulting composition containing bromocyanamide and fipronil showed better control effects against mosquitoes, flies and cockroaches than in Example 13.

[0164] The stirring speeds in step S1 of Examples 15 and 16 are different from those in Example 3; the stirring speeds in step S2 of Examples 17 and 18 are different from those in Example 3; and the stirring speeds in step S3 of Examples 19 and 20 are different from those in Example 3. The compositions containing bromocyanamide and fipronil prepared in Examples 15-20 are less effective against mosquitoes, flies, and cockroaches than those in Example 3.

[0165] The above are all preferred embodiments of this application, and are not intended to limit the scope of protection of this application. Therefore, all equivalent changes made in accordance with the structure, shape and principle of this application should be covered within the scope of protection of this application.

Claims

1. A composition containing bromocyanamide and fipronil, characterized in that, The raw material composition, by weight parts, includes: 5-10 parts of bromocyanamide, 10-15 parts of fipronil, 1-2 parts of dextromethorphan, 0.3-1 parts of dextromethorphan, 1-1.5 parts of azone, 5-10 parts of polyethylene glycol, 0.5-1 part of matrine, 0.5-1.5 parts of grapefruit peel extract, 0.5-1 part of capsicum extract, 0.5-1 part of plant essential oil, and 80-100 parts of solvent. The weight ratio of bromocyanamide to dextromethorphan is 8-12:1, and the molecular weight of polyethylene glycol is 10,000-100,000.

2. The composition containing bromocyanamide and dinotefuran according to claim 1, characterized in that, By weight, its raw material composition includes: 6-8 parts of bromocyanamide, 12-13 parts of fipronil, 1.5-2 parts of dextromethorphan, 0.5-0.8 parts of dextromethorphan, 1.3-1.5 parts of azone, 6-8 parts of polyethylene glycol, 0.8-1 part of matrine, 0.8-1.2 parts of grapefruit peel extract, 0.8-1 part of capsicum extract, 0.8-1 part of plant essential oil, and 85-95 parts of solvent.

3. The composition containing bromocyanamide and dinotefuran according to claim 1, characterized in that, The weight ratio of the fipronil to the matrine is 13-15:

1.

4. The composition containing bromocyanamide and dinotefuran according to claim 1, characterized in that, The plant essential oil is selected from at least one of tea tree oil, peppermint oil, chamomile oil, and eucalyptus oil.

5. The composition containing bromocyanamide and dinotefuran according to claim 1, characterized in that, The solvent is selected from at least one of methanol, ethanol, ethyl acetate, and ethyl ketone.

6. A method for preparing the composition containing bromocyanamide and dinotefuran according to claim 1, characterized in that, Includes the following steps: S1. Mix the bromocyanamide, fipronil, dextromethorphan, dextromethorphan, and azone, and stir for 10-30 minutes to obtain mixture A. S2. Add the mixture A and the polyethylene glycol diamine to the solvent and stir for 30-60 minutes to obtain the mixture B. S3. Add the matrine, grapefruit peel extract, chili extract and plant essential oil to the mixture B, stir and mix for 60-90 minutes to obtain the composition containing bromocyanamide and fipronil.

7. The method for preparing the composition containing bromocyanamide and dinotefuran according to claim 6, characterized in that, In step S1, the stirring speed is 500~700 r / min; in step S2, the stirring speed is 600~700 r / min; and in step S3, the stirring speed is 600~800 r / min.

8. The application of the composition containing bromocyanamide and dinotefuran as described in any one of claims 1 to 5 in the field of pest control.

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