A bacteriostatic, lubricating, coconut oil-containing composition and method of making same
By preparing a composition containing virgin coconut oil, coconut oil extract, Zanthoxylum nitidum extract and Ligustrum lucidum extract, the problem of the narrow application range of coconut oil was solved, and the high-efficiency antibacterial and lubricating effects were achieved, while improving the stability and emulsifying properties of the composition.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- HAIKOU ZHIZHISU BIOLOGICAL RESOURCES RES INST CO LTD
- Filing Date
- 2024-03-21
- Publication Date
- 2026-06-05
Smart Images
Figure BDA0004752258670000061 
Figure BDA0004752258670000071
Abstract
Description
Technical Field
[0001] This invention relates to the field of coconut oil product preparation technology, and in particular to a method for preparing an antibacterial and lubricating coconut oil-containing composition. Background Technology
[0002] Coconut oil is an oil extracted from the flesh of coconut palms. Due to its high saturation level (over 90%), it exhibits good stability, antioxidant properties, and high-temperature resistance. More than 50% of coconut oil is lauric acid, a medium-chain fatty acid and a major component of breast milk. Lauric acid can enhance the body's immunity and has strong antibacterial properties against bacteria, viruses, and even intestinal parasites.
[0003] Chinese patent CN103589537A describes a beauty and antibacterial soap that enhances its cleaning power by adding coconut oil, palm oil, and olive oil, thus giving it antibacterial and whitening effects. This patent adds coconut oil to the soap to improve its antibacterial effect. To broaden the application range of coconut oil, a method for preparing an antibacterial and lubricating coconut oil-containing composition is proposed. Summary of the Invention
[0004] In view of this, the present invention proposes a method for preparing an antibacterial and lubricating coconut oil-containing composition to solve the above problems.
[0005] The technical solution of this invention is implemented as follows:
[0006] An antibacterial and lubricating coconut oil composition, comprising, by weight, 10-12 parts virgin coconut oil, 8-12 parts coconut oil extract, 0.1-0.2 parts Zanthoxylum nitidum extract and 0.3-0.4 parts Ligustrum lucidum extract.
[0007] Furthermore, the method for preparing the coconut oil extract involves mixing virgin coconut oil and water, adding sodium hydroxide, heating to 270-300℃ and reacting for 5-7 hours, centrifuging, collecting the precipitate, mixing the precipitate with water, adjusting the pH to 6-7, dialyzing, collecting the dialysate, and drying.
[0008] Furthermore, the virgin coconut oil is extracted using supercritical carbon dioxide extraction at an extraction pressure of 35 MPa, an extraction temperature of 55°C, an extraction time of 75 min, and a carbon dioxide flow rate of 18 L / h.
[0009] Furthermore, the preparation method of the Zanthoxylum nitidum extract is to pulverize Zanthoxylum nitidum to obtain Zanthoxylum nitidum powder, and then extract the Zanthoxylum nitidum powder with an ethanol solution.
[0010] Furthermore, the preparation method of the privet extract is to pulverize privet fruit to obtain privet fruit powder, and then add the privet fruit powder to an ethanol solution for ultrasonic extraction.
[0011] Furthermore, the concentration of the ethanol solution is 60-70 wt%, the ratio of Zanthoxylum bungeanum powder to ethanol solution is 1 g: 50-70 ml, the extraction time is 3-5 h / time, the number of extractions is 2-3 times, and the extraction temperature is 50-60℃.
[0012] Furthermore, the ratio of privet fruit to ethanol solution is 1g:80-120ml, the ultrasonic extraction temperature is 30-40℃, the ultrasonic time is 20-30min, and the ultrasonic power is 380-450W.
[0013] Furthermore, the mass ratio of the virgin coconut oil to water is 1:1.5-1.8, and 1-3 mol / L sodium hydroxide is added to adjust the pH to 8-9.
[0014] Furthermore, the method for preparing the antibacterial and lubricating coconut oil-containing composition involves mixing virgin coconut oil, coconut oil extract, Zanthoxylum nitidum extract, and Ligustrum lucidum extract. The coconut oil mixture is stirred at 25-30°C for 20-30 minutes to obtain a coconut oil mixture. Water is added to the coconut oil mixture in two batches and mixed to obtain the finished product.
[0015] Furthermore, the process of adding water to the coconut oil mixture in two stages involves the following steps: First, water is added to the coconut oil mixture at a mass ratio of 1:1.1-1.3, and the mixture is stirred at 15000-16000 rpm for 5-8 minutes. Second, water is added to the coconut oil mixture at a rate of 7-10 ml / min, with a mass ratio of 1:0.6-0.8, and the mixture is stirred at 10000-12000 rpm for 2-4 minutes to obtain the final product.
[0016] Compared with the prior art, the beneficial effects of the present invention are:
[0017] This invention utilizes virgin coconut oil, coconut oil extract, Zanthoxylum nitidum extract, and Ligustrum lucidum extract to prepare a composition with lubricating and antibacterial effects. The virgin coconut oil is extracted using supercritical carbon dioxide extraction, resulting in a high extraction rate. The virgin coconut oil contains 55.17% lauric acid. Extraction of virgin coconut oil enhances the antibacterial effect of the composition and also helps reduce the particle size of the finished product during processing, leading to a more stable product. Furthermore, by extracting the active ingredients from Zanthoxylum nitidum and Ligustrum lucidum, this invention not only improves the efficacy of the finished product, but the Zanthoxylum nitidum extract and Ligustrum lucidum extract also act as emulsifiers, exhibiting better hydration and emulsifying properties, further enhancing the stability of the finished product. Detailed Implementation
[0018] To better understand the technical content of this invention, specific embodiments are provided below to further illustrate the invention.
[0019] Unless otherwise specified, the experimental methods used in the embodiments of this invention are all conventional methods.
[0020] Unless otherwise specified, all materials and reagents used in the embodiments of this invention are commercially available.
[0021] Example 1
[0022] Coconut meat was dried at 50℃ for 36 hours and then crushed. The virgin coconut oil was obtained by supercritical carbon dioxide extraction at an extraction pressure of 35MPa, an extraction temperature of 55℃, an extraction time of 75min, and a carbon dioxide flow rate of 18L / h.
[0023] The lauric acid content of virgin coconut oil was determined using the gas chromatography method disclosed by Zhang Shuqiong for the determination of coconut oil components. The lauric acid content of the virgin coconut oil obtained in Example 1 was 55.17%.
[0024] Example 2
[0025] The method for preparing coconut oil extract is as follows: virgin coconut oil and water are mixed at a mass ratio of 1:1.5, 1 mol / L sodium hydroxide is added to adjust the pH to 8, the temperature is raised to 270℃ and reacted for 5 h, centrifuged, the precipitate is collected, the precipitate is mixed with water, the pH is adjusted to 6, and dialyzed with deionized water at 4℃ for 48 h, with the water changed every 8 h, the dialysate is collected and dried.
[0026] The preparation method of Zanthoxylum nitidum extract is as follows: Zanthoxylum nitidum is pulverized to obtain Zanthoxylum nitidum powder. The ratio of Zanthoxylum nitidum powder to 60wt% ethanol solution is 1g:50ml. The extraction time is 3h / time, the number of extractions is 2, the extraction temperature is 50℃, the extracts are combined and dried to obtain Zanthoxylum nitidum extract.
[0027] Weigh out 10 parts by weight of virgin coconut oil, 8 parts of coconut oil extract, 0.1 parts of Zanthoxylum nitidum extract and 0.3 parts of Ligustrum lucidum extract.
[0028] Virgin coconut oil, coconut oil extract, Zanthoxylum nitidum extract, and Ligustrum lucidum extract were mixed. The coconut oil mixture was stirred at 25°C for 20 minutes to obtain a coconut oil mixture. Water was added to the coconut oil mixture at a mass ratio of 1:1.1, and the mixture was stirred at 16,000 rpm for 5 minutes. Water was then added to the coconut oil mixture at a rate of 7 ml / min at a mass ratio of 1:0.6, and the mixture was stirred at 10,000 rpm for 2 minutes to obtain the final product.
[0029] Example 3
[0030] The method for preparing coconut oil extract is as follows: virgin coconut oil and water are mixed at a mass ratio of 1:1.8, 3 mol / L sodium hydroxide is added to adjust the pH to 9, the temperature is raised to 300℃ and reacted for 7 h, centrifuged, the precipitate is collected, the precipitate is mixed with water, the pH is adjusted to 7, and dialyzed with deionized water at 4℃ for 48 h, with the water changed every 8 h, the dialysate is collected and dried.
[0031] The preparation method of Zanthoxylum nitidum extract is as follows: Zanthoxylum nitidum is pulverized to obtain Zanthoxylum nitidum powder. The ratio of Zanthoxylum nitidum powder to 70wt% ethanol solution is 1g:70ml. The extraction time is 5h / time, the number of extractions is 3, the extraction temperature is 60℃, the extracts are combined, dried, and Zanthoxylum nitidum extract is obtained.
[0032] Weigh out 12 parts by weight of virgin coconut oil, 12 parts of coconut oil extract, 0.2 parts of Zanthoxylum nitidum extract and 0.4 parts of Ligustrum lucidum extract.
[0033] Virgin coconut oil, coconut oil extract, Zanthoxylum nitidum extract, and Ligustrum lucidum extract were mixed. The coconut oil mixture was stirred at 30°C for 30 minutes to obtain a coconut oil mixture. Water was added to the coconut oil mixture at a mass ratio of 1:1.3, and the mixture was stirred at 16000 rpm for 8 minutes. Water was then added to the coconut oil mixture at a rate of 10 ml / min at a mass ratio of 1:0.8, and the mixture was stirred at 12000 rpm for 4 minutes to obtain the final product.
[0034] Example 4
[0035] The coconut oil extract was prepared by mixing virgin coconut oil and water at a mass ratio of 1:1.65, adding 2 mol / L sodium hydroxide to adjust the pH to 8.5, heating to 280℃ and reacting for 6 hours, centrifuging, collecting the precipitate, mixing the precipitate with water, adjusting the pH to 6.5, dialyzing with deionized water at 4℃ for 48 hours, changing the water every 8 hours, collecting the dialysate and drying it.
[0036] The preparation method of Zanthoxylum nitidum extract is as follows: Zanthoxylum nitidum is pulverized to obtain Zanthoxylum nitidum powder. The ratio of Zanthoxylum nitidum powder to 65wt% ethanol solution is 1g:60ml. The extraction time is 4h / time, the number of extractions is 3, and the extraction temperature is 55℃. The extracts are combined and dried to obtain Zanthoxylum nitidum extract.
[0037] Weigh out 11 parts by weight of virgin coconut oil, 10 parts of coconut oil extract, 0.15 parts of Zanthoxylum nitidum extract and 0.35 parts of Ligustrum lucidum extract.
[0038] Virgin coconut oil, coconut oil extract, Zanthoxylum nitidum extract, and Ligustrum lucidum extract were mixed. The coconut oil mixture was stirred at 27°C for 25 minutes to obtain a coconut oil mixture. Water was added to the coconut oil mixture at a mass ratio of 1:1.2, and the mixture was stirred at 1500 rpm for 7 minutes. Water was then added to the coconut oil mixture at a rate of 8 ml / min at a mass ratio of 1:0.7, and the mixture was stirred at 11000 rpm for 3 minutes to obtain the final product.
[0039] Comparative Example 1
[0040] Based on Example 4, the raw material components were adjusted as follows:
[0041] The coconut oil extract was prepared by mixing virgin coconut oil and water at a mass ratio of 1:1.65, adding 2 mol / L sodium hydroxide to adjust the pH to 8.5, heating to 280℃ and reacting for 6 hours, centrifuging, collecting the precipitate, mixing the precipitate with water, adjusting the pH to 6.5, dialyzing with deionized water at 4℃ for 48 hours, changing the water every 8 hours, collecting the dialysate and drying it.
[0042] The preparation method of Zanthoxylum nitidum extract is as follows: Zanthoxylum nitidum is pulverized to obtain Zanthoxylum nitidum powder. The ratio of Zanthoxylum nitidum powder to 65wt% ethanol solution is 1g:60ml. The extraction time is 4h / time, the number of extractions is 3, and the extraction temperature is 55℃. The extracts are combined and dried to obtain Zanthoxylum nitidum extract.
[0043] Weigh out 11 parts by weight of virgin coconut oil, 10 parts of coconut oil extract, 0.4 parts of Zanthoxylum nitidum extract and 0.1 parts of Ligustrum lucidum extract.
[0044] Virgin coconut oil, coconut oil extract, Zanthoxylum nitidum extract, and Ligustrum lucidum extract were mixed. The coconut oil mixture was stirred at 27°C for 25 minutes to obtain a coconut oil mixture. Water was added to the coconut oil mixture at a mass ratio of 1:1.2, and the mixture was stirred at 1500 rpm for 7 minutes. Water was then added to the coconut oil mixture at a rate of 8 ml / min at a mass ratio of 1:0.7, and the mixture was stirred at 11000 rpm for 3 minutes to obtain the final product.
[0045] Comparative Example 2
[0046] The preparation method of the coconut oil composition was adjusted based on Example 4, specifically as follows:
[0047] The coconut oil extract was prepared by mixing virgin coconut oil and water at a mass ratio of 1:1.65, adding 2 mol / L sodium hydroxide to adjust the pH to 8.5, heating to 280℃ and reacting for 6 hours, centrifuging, collecting the precipitate, mixing the precipitate with water, adjusting the pH to 6.5, dialyzing with deionized water at 4℃ for 48 hours, changing the water every 8 hours, collecting the dialysate and drying it.
[0048] The preparation method of Zanthoxylum nitidum extract is as follows: Zanthoxylum nitidum is pulverized to obtain Zanthoxylum nitidum powder. The ratio of Zanthoxylum nitidum powder to 65wt% ethanol solution is 1g:60ml. The extraction time is 4h / time, the number of extractions is 3, and the extraction temperature is 55℃. The extracts are combined and dried to obtain Zanthoxylum nitidum extract.
[0049] Weigh out 11 parts by weight of virgin coconut oil, 10 parts of coconut oil extract, 0.15 parts of Zanthoxylum nitidum extract and 0.35 parts of Ligustrum lucidum extract.
[0050] Virgin coconut oil, coconut oil extract, Zanthoxylum nitidum extract, and Ligustrum lucidum extract were mixed. The coconut oil mixture was stirred at 27°C for 25 minutes to obtain a coconut oil mixture. Water was added to the coconut oil mixture at a mass ratio of 1:1.2, and the mixture was stirred at 1500 rpm for 7 minutes. Water was added to the coconut oil mixture again at a mass ratio of 1:0.7, and the mixture was stirred at 11000 rpm for 3 minutes to obtain the finished product.
[0051] Experimental Example 1
[0052] Antibacterial test
[0053] Test strains: Gardnerella vaginalis, Candida albicans
[0054] Experimental reagents: Coconut oil-containing compositions prepared in Example 4 and Comparative Examples 1-2
[0055] Experimental procedure: Gardnerella vaginalis and Candida albicans were diluted to a concentration of 1×10⁻⁶ using PBS buffer. 7 CPU / ml, the diluted bacterial solution was added to LB solid agar medium, 0.5 ml of the coconut oil-containing composition was added to the medium, and the mixture was incubated at 37°C for 24 h. The diameter of the inhibition zone was measured using the streak method.
[0056] name Gardnerella vaginalis (mm) Candida albicans (mm) Example 4 14.95 20.78 Comparative Example 1 10.59 12.67 Comparative Example 2 13.06 18.94
[0057] Experimental results show that the coconut oil-containing composition prepared in this invention has a significant inhibitory effect on Gardnerella vaginalis and Candida albicans.
[0058] Experimental Example 2
[0059] The average particle size D (μm) of the finished product was determined using a BT-9300H laser particle size analyzer.
[0060] Experimental procedure: The average particle size of the coconut oil-containing compositions prepared in Example 4 and Comparative Examples 1-2 was measured at 0 days, 30 days, and 60 days, and the storage temperature was 24°C.
[0061]
[0062]
[0063] Experimental results show that the coconut oil-containing composition prepared by this invention has a small particle size, and the average particle size does not change significantly after 60 days of storage, indicating that the finished product prepared by this invention has good stability. In Comparative Example 1, the raw material components were adjusted, resulting in a larger particle size. With prolonged storage, the average particle size of the coconut oil-containing composition increased, indicating that the emulsion exhibited coagulation or aggregation. In this invention, the rational proportioning of virgin coconut oil, coconut oil extract, Zanthoxylum nitidum extract, and Ligustrum lucidum extract significantly improves the stability of the finished product. In Comparative Example 2, adjusting the preparation method of the coconut oil composition resulted in an increase in the average particle size of the coconut oil-containing composition and a decrease in stability.
[0064] The above description is only a preferred embodiment of the present invention and is not intended to limit the present invention. Any modifications, equivalent substitutions, improvements, etc., made within the spirit and principles of the present invention should be included within the protection scope of the present invention.
Claims
1. A composition containing coconut oil that has antibacterial and lubricating properties, characterized in that, The composition comprises, by weight, 10-12 parts virgin coconut oil, 8-12 parts coconut oil extract, 0.1-0.2 parts Zanthoxylum nitidum extract and 0.3-0.4 parts Ligustrum lucidum extract; The method for preparing the coconut oil extract is as follows: virgin coconut oil and water are mixed, sodium hydroxide is added and mixed, the mixture is heated to 270-300℃ and reacted for 5-7 hours, centrifuged, the precipitate is collected, the precipitate is mixed with water, the pH is adjusted to 6-7, dialyzed, the dialysate is collected and dried. The preparation method of the Zanthoxylum nitidum extract is to pulverize Zanthoxylum nitidum to obtain Zanthoxylum nitidum powder, and then extract the Zanthoxylum nitidum powder with ethanol solution. The preparation method of the privet fruit extract is to crush privet fruit into privet fruit powder, and then add privet fruit powder to ethanol solution for ultrasonic extraction. The method for preparing the antibacterial and lubricating coconut oil-containing composition is as follows: virgin coconut oil, coconut oil extract, Zanthoxylum nitidum extract, and Ligustrum lucidum extract are mixed and stirred at 25-30℃ for 20-30 minutes to obtain a coconut oil mixture. Water is added to the coconut oil mixture in two batches. In the first batch, water is added to the coconut oil mixture at a mass ratio of 1:1.1-1.3, and the mixture is stirred at 15000-16000 rpm for 5-8 minutes. In the second batch, water is added to the coconut oil mixture at a rate of 7-10 ml / min at a mass ratio of 1:0.6-0.8, and the mixture is stirred at 10000-12000 rpm for 2-4 minutes to obtain the finished product.
2. The antibacterial and lubricating coconut oil-containing composition as described in claim 1, characterized in that, In the preparation method of the Zanthoxylum nitidum extract, the concentration of the ethanol solution is 60-70 wt%, the ratio of Zanthoxylum nitidum powder to ethanol solution is 1 g: 50-70 ml, the extraction time is 3-5 h / time, the number of extractions is 2-3 times, and the extraction temperature is 50-60℃.
3. The antibacterial and lubricating coconut oil-containing composition as described in claim 1, characterized in that, In the preparation method of the privet fruit extract, the ratio of privet fruit to ethanol solution is 1g:80-120ml, the concentration of ethanol solution is 65-75wt%, the ultrasonic extraction temperature is 30-40℃, the ultrasonic time is 20-30min, and the ultrasonic power is 380-450W.
4. The antibacterial and lubricating coconut oil-containing composition as described in claim 1, characterized in that, The mass ratio of the virgin coconut oil to water is 1:1.5-1.8, and 1-3 mol / L sodium hydroxide is added to adjust the pH to 8-9.