Use of prunella vulgaris extract in preventing and treating fish parasitic disease infection

As a drug for the prevention and treatment of parasitic diseases in fish, Prunella vulgaris extract, by preparing a methanol extract and adding it to fish feed, solves the problems of toxicity and environmental pollution of existing chemical agents, and achieves safe and efficient killing of Trichodina and healthy growth of fish.

CN118453690BActive Publication Date: 2026-06-05INST OF AQUATIC LIFE ACAD SINICA +1

Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
INST OF AQUATIC LIFE ACAD SINICA
Filing Date
2024-05-14
Publication Date
2026-06-05

AI Technical Summary

Technical Problem

Existing chemical agents have problems such as high toxicity, disruption of the micro-ecological balance, and environmental pollution when used to control fish parasitic diseases. Finding safe and effective alternative drugs is an urgent problem to be solved.

Method used

Prunella vulgaris extract was used as a drug for the prevention and treatment of parasitic diseases in fish. A methanol extract of Prunella vulgaris was prepared and added to fish feed at a concentration of 2.5–10 μg/ml to kill fish parasites.

Benefits of technology

Prunella vulgaris extract effectively kills Chilodonella asiatica, inhibits its growth, enhances fish immunity, reduces plasma ALT and AST levels, promotes fish growth, and has no toxic side effects.

✦ Generated by Eureka AI based on patent content.

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Abstract

The application discloses application of Prunella vulgaris extract in prevention and treatment of fish parasitic disease infection. Inclined tube worm in-vitro soaking experiments show that the insecticidal effect of Prunella vulgaris extract and zinc sulfate is equivalent after 48 hours, and the mortality rate is above 95.44%; based on the growth condition of rainbow trout feeding on Prunella vulgaris extract, the specific growth rate of fish is significantly improved, the growth performance is improved, and the growth of fish is promoted; the plasma biochemical indexes after parasitic infection show that the addition of 0.25% to 1% Prunella vulgaris extract in feed can significantly reduce stress caused by pathogenic stress and protect the health of fish liver.
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