A plaster for treating chronic neck, shoulder, waist and leg pain and a method for manufacturing the same

Abstract

The application discloses a plaster for treating chronic neck-shoulder-lumb-and-leg pain and a preparation method thereof, and belongs to the technical field of medicines. The plaster is prepared from the following raw materials in parts by weight: herba rhizomatis, herba tubae, fructus, drynaria, eucommia ulmoides, rhizoma, radix paeoniae rubra, ligusticum, angelica sinensis, rhizoma, herba, eupolyphaga, palmate begonia, radix, artemisia rupestris, rhizoma, radix, rhizoma, radix, radix, radix, radix, and radix angelicae. The plaster has the advantages that the plaster has safe, effective, cheap, and non-toxic medicinal components, is prepared according to traditional ancient methods, and is combined with modern transdermal absorption technology and anti-allergy formula, so that the plaster is more convenient, safe, and green to use. The plaster can be directly applied to a pain part, reaches the disease site, has more remarkable curative effect, is more convenient to use, can treat both symptoms and root causes, and has the effects of long-term relieving and even radical curing.

Description

Technical Field

[0001] This invention relates to the field of medical technology, and more specifically, to a plaster for treating chronic neck, shoulder, back and leg pain and its manufacturing method. Background Technology

[0002] Due to the widespread use of electronic products, many people in modern society suffer from common ailments such as cervical spondylosis and lumbar spondylosis because of prolonged periods of looking down and sitting. In general, Western medicine treats neck, shoulder, back and leg pain through conventional methods, such as surgery depending on the specific cause, or non-steroidal anti-inflammatory drugs, analgesics, and anti-osteoporosis medications to address the symptoms. However, the disadvantages are that surgery carries high risks, and the effects of drug treatment are not always satisfactory and have significant side effects. Traditional Chinese medicine believes that the external causes of neck, shoulder, back and leg pain are the invasion of external pathogens such as wind, cold and dampness, while the internal cause is the deficiency of vital energy. Therefore, it is generally believed that the treatment of chronic neck, shoulder, back and leg pain should focus on tonifying the liver and kidneys and strengthening the tendons and bones to address the root cause, promoting blood circulation and unblocking the meridians, and dispelling wind and dampness to relieve pain.

[0003] In current technologies, surgery causes significant damage to the human body and fails to adequately address the biomechanical causes, resulting in generally poor long-term efficacy. Chemical drugs have a significant impact on gastrointestinal function, and long-term use can lead to patient resistance. Moreover, current treatments primarily focus on relieving pain and addressing symptoms in the acute phase, rather than addressing the root cause and symptoms in the chronic phase. Currently, traditional Chinese medicine treatments for neck, shoulder, back, and leg pain often use herbs containing highly toxic substances such as Aconitum carmichaelii and Aconitum kusnezoffii, which have cardiotoxic, neurotoxic, and skin toxicity. Other treatments include massage, traction, physiotherapy, acupuncture, small needle knife therapy, and special needle release techniques. While these methods can provide temporary relief, relapse is common after treatment is discontinued.

[0004] Therefore, how to address the additional physical damage caused to patients by long-term use of Western medicine or Chinese medicine containing Aconitum carmichaelii or Aconitum kusnezoffii, as well as the recurrence rate of chronic neck, shoulder, back and leg pain after conventional Western medical treatment, are problems that urgently need to be solved by those skilled in the art. Summary of the Invention

[0005] To overcome the problems of additional harm to the body caused by long-term use of Western medicine or traditional Chinese medicine containing aconite and cassia in existing technologies, and the easy recurrence of chronic neck, shoulder, back, and leg pain after conventional Western medicine treatment, this invention provides a plaster for treating chronic neck, shoulder, back, and leg pain and its manufacturing method. The plaster, with safe medicinal ingredients, can be directly applied to the painful area, reaching the affected area directly, resulting in more significant efficacy, easier use, and the ability to treat both the symptoms and the root cause, providing long-term relief or even a cure. The specific technical solution is as follows:

[0006] A plaster for treating chronic neck, shoulder, back and leg pain, characterized in that it is prepared from at least the following raw materials by weight: 20-80 parts of Curculigo orchioides, 15-60 parts of Epimedium, 20-80 parts of Drynaria fortunei, 20-80 parts of Broussonetia papyrifera, 20-80 parts of Eucommia ulmoides, and 20-80 parts of Dipsacus asper.

[0007] Based on the above technical solution, the present invention can be further improved as follows, and the plaster for treating chronic neck, shoulder, waist and leg pain is prepared from at least the following raw materials: 10-50 parts of Paeonia lactiflora, 10-50 parts of Ligusticum chuanxiong, 10-50 parts of Angelica sinensis, 15-60 parts of Corydalis yanhusuo, 15-60 parts of Homalomena occulta, 5-30 parts of Eupolyphaga sinensis, 15-60 parts of Pterocarya stenoptera, and 15-60 parts of Achyranthes bidentata.

[0008] Furthermore, the plaster used to treat chronic neck, shoulder, back and leg pain is prepared from at least the following raw materials: 15-60 parts of Artemisia argyi, 15-60 parts of Lycopodium clavatum, 15-60 parts of Clematis chinensis, 15-60 parts of Clematis armandii, 15-60 parts of Clematis chinensis, 15-60 parts of Geranium wilfordii and 15-60 parts of Pyrola rotundifolia.

[0009] Furthermore, the plaster used to treat chronic neck, shoulder, back and leg pain is prepared from at least the following raw materials: 5-30 parts of Notopterygium incisum and 5-30 parts of Angelica pubescens.

[0010] Furthermore, the plaster used to treat chronic neck, shoulder, lower back, and leg pain is prepared from at least the following raw materials: 25-75 parts of Curculigo orchioides, 20-55 parts of Epimedium brevicornu, 25-75 parts of Drynaria fortunei, 25-75 parts of Broussonetia papyrifera, 25-75 parts of Eucommia ulmoides, 25-75 parts of Dipsacus asper, 15-45 parts of Paeonia lactiflora, 15-45 parts of Ligusticum chuanxiong, 15-45 parts of Angelica sinensis, 20-55 parts of Corydalis yanhusuo, and 1000 grams of chrysanthemum greens. 20-55 parts of *Gynostemma pentaphyllum*, 10-25 parts of *Eupolyphaga sinensis*, 20-55 parts of *Achyranthes bidentata*, 20-55 parts of *Artemisia argyi*, 20-55 parts of *Lycopodium clavatum*, 20-55 parts of *Clematis chinensis*, 20-55 parts of *Hedyotis diffusa*, 20-55 parts of *Gnaphalium affine*, 20-55 parts of *Platycodon grandiflorus*, 20-55 parts of *Geranium wilfordii*, 20-55 parts of *Pyrola rotundifolia*, 10-25 parts of *Notopterygium incisum*, and 10-25 parts of *Angelica pubescens*.

[0011] The external plaster formula of this invention has a reasonable combination of ingredients, with each ingredient working synergistically to enhance its effects. It has the functions of tonifying the kidneys and strengthening bones, promoting blood circulation and removing blood stasis, and dispelling wind and unblocking the meridians. It is particularly suitable for the treatment of chronic neck, shoulder, back and leg pain. By treating internal diseases externally, the medicinal effects penetrate the skin and reach the meridians directly, regulating the qi, blood, yin and yang of the internal organs, thereby achieving the purpose of supporting the body's resistance and eliminating pathogenic factors, and curing diseases.

[0012] This invention provides a method for preparing a plaster for treating chronic neck, shoulder, back, and leg pain, comprising the following steps:

[0013] A. Soak the ingredients in pre-prepared sesame oil, with a ratio of 1:2 (medicinal oil to sesame oil), ensuring they are thoroughly soaked.

[0014] B. Heat the soaked Chinese herbal medicine slices and medicinal oil from step A, stirring constantly to ensure even heating of the medicine. First, use high heat, then low heat, until the herbs are golden brown or blackened. Once all the herbs float to the surface of the oil, remove the residue and filter out the residue, leaving only the medicinal oil.

[0015] C. Put the litharge into the prepared iron pot and stir-fry repeatedly to remove the moisture from the litharge;

[0016] D. Put the medicinal oil obtained in step B into a pot, first bring it to a high heat so that the oil bubbles rise from the inside out, then simmer the medicinal oil in the pot over a low heat. When the gas rises around the pot, occasionally dip a small amount into the prepared cold water, and the water droplets will form beads.

[0017] E. Add 7-40 kg of litharge obtained in step C to the refined medicinal oil and stir constantly to ensure that litharge reacts fully with the medicinal oil. Generally, the ratio is 195 g litharge to 500 g medicinal oil (16:7). However, the ratio may vary slightly depending on the season. More litharge is needed in summer and less in autumn and winter.

[0018] F. Remove the fire toxin: Quickly immerse the refined paste in prepared cold water, change the water once a day, and let it sit for more than a week;

[0019] G. Adding fine ingredients: Add precious and fine medicines, such as camphor and borneol, to the melted plaster and stir constantly;

[0020] H. Pressing the plaster: Remove the cooked plaster from the heat, pick it up with bamboo chopsticks, place it on the prepared cloth, and use the bamboo chopsticks to press the center of the cloth and rotate it around to spread the plaster evenly. After the plaster cools and solidifies, it can be cut into pieces of appropriate size.

[0021] Furthermore, the weight range of the sesame oil in step A is 0.6-6 kg.

[0022] Furthermore, the oil temperature range for extracting the medicinal materials in step B is 200-220℃.

[0023] Furthermore, the weight range of litharge in step C is 7-40 kg.

[0024] Furthermore, the oil temperature range during refining in step D is 200-300℃.

[0025] This invention relates to a method for preparing a plaster for treating chronic neck, shoulder, back, and leg pain. It employs traditional processing and refining methods, combined with modern transdermal absorption technology and an anti-allergy formula. Using this method not only improves the purity of the plaster but also significantly enhances its therapeutic effect.

[0026] The inventive concept of this invention is as follows: Six herbs—Epimedium, Curculigo orchioides, Broussonetia papyrifera, Drynaria fortunei, Eucommia ulmoides, and Dipsacus asper—are used as the principal herbs to tonify the kidneys and strengthen bones, promote healing of injuries and relieve pain. This treatment primarily targets the main pathogenesis of chronic neck and lower back pain—liver and kidney deficiency leading to malnourishment of tendons and bones. Among them, Epimedium and Curculigo orchioides tonify kidney yang, while Broussonetia papyrifera tonifies kidney yin, achieving a balance of yin and yang tonification. Drynaria fortunei tonifies the kidneys and strengthens bones, promotes healing of injuries and relieves pain, making it particularly suitable for kidney deficiency causing lower back pain and tendon and bone injuries. Eucommia ulmoides tonifies the liver and kidneys and strengthens tendons and bones, showing good efficacy for lower back pain and weakness in the legs and knees. Dipsacus asper has the effects of tonifying the liver and kidneys, strengthening tendons and bones, and promoting healing of fractures, making it suitable for liver and kidney deficiency and tendon and bone injuries.

[0027] In terms of the herbal medicine, eight herbs were selected: ground beetle, red peony root, chuanxiong rhizome, angelica root, corydalis rhizome, primordial ginseng, dwarf dragon's blood, and achyranthes root. These herbs all have the effects of promoting qi and blood circulation, clearing the meridians and removing blood stasis, and are used to treat chronic neck and back pain, which is characterized by blood stasis due to prolonged illness.

[0028] The adjuvant herbs include a variety of traditional Chinese medicinal materials such as Artemisia argyi, Lycopodium clavatum, Clematis chinensis, Clematis armandii, Geranium wilfordii, and Pyrola rotundifolia. They either work in conjunction with the principal and assistant herbs to enhance the therapeutic effect or directly treat secondary symptoms. For example, Artemisia argyi dispels wind and dampness, invigorates blood and relieves pain; Lycopodium clavatum and Clematis chinensis dispel wind and dampness, relax muscles and unblock meridians; Clematis armandii invigorates blood and relieves pain, reduces swelling and detoxifies; Clematis armandii dispels wind and dampness, relaxes muscles and invigorates blood; Geranium wilfordii dispels wind and dampness, unblocks meridians; and Pyrola rotundifolia dispels wind and dampness, strengthens muscles and bones.

[0029] In terms of the medicinal ingredients, two herbs, Qianghuo and Duhuo, were selected. They not only have the effects of dispelling wind and dampness, relieving pain and numbness, but also guide the other herbs in the prescription to the affected area to exert their therapeutic effects.

[0030] Beneficial effects:

[0031] The beneficial effects of adopting the technical solution of this invention are as follows:

[0032] (1) The external plaster formula of the present invention has a reasonable combination of ingredients, and the combination of the ingredients complements each other. It has the effects of tonifying the kidney and strengthening bones, promoting blood circulation and removing blood stasis, and dispelling wind and unblocking the meridians. It is especially suitable for the treatment of chronic neck, shoulder, waist and leg pain. By treating internal diseases externally, the medicinal effects can penetrate the skin and reach the meridians, regulate the qi, blood, yin and yang of the internal organs, and achieve the purpose of supporting the body's resistance and eliminating pathogens, and curing diseases.

[0033] (2) The method for making the plaster for treating chronic neck, shoulder, back and leg pain of the present invention adopts the traditional ancient processing and refining method, and combines modern transdermal absorption technology and anti-allergy formula. The method for making the plaster using the present invention can not only improve the purity of the plaster, but also significantly improve the efficacy of plaster application. Detailed Implementation

[0034] The principles and features of the present invention are described below. The examples given are only for explaining the present invention and are not intended to limit the scope of the present invention.

[0035] Example 1

[0036] A. Soak 30 parts of Curculigo orchioides, 20 parts of Epimedium, 30 parts of Drynaria fortunei, 30 parts of Broussonetia papyrifera, 30 parts of Eucommia ulmoides, 30 parts of Dipsacus asper, 15 parts of Paeonia lactiflora, 15 parts of Ligusticum chuanxiong, 15 parts of Angelica sinensis, 20 parts of Corydalis yanhusuo, 20 parts of Homalomena occulta, 10 parts of Eupolyphaga sinensis, 20 parts of Achyranthes bidentata, 20 parts of Artemisia argyi, 20 parts of Lycopodium clavatum, 20 parts of Clematis chinensis, 20 parts of Clematis armandii, 20 parts of Clematis chinensis ...10 parts of Notopterygium incisum, and 10 parts of Angelica pubescens in pre-prepared sesame oil. The ratio of medicine to oil should be 1:2, and the medicine should be thoroughly soaked.

[0037] B. Heat the soaked Chinese herbal medicine slices and medicinal oil from step A, stirring constantly to ensure even heating. First, use high heat, then low heat, until the herbs are golden brown or blackened. Once all the herbs float to the surface of the oil, remove the residue and filter out the remaining medicinal oil.

[0038] C. Put the litharge into the prepared iron pot and stir-fry repeatedly to remove the moisture from the litharge.

[0039] D. Place the medicinal oil obtained in step B into a pot. First, bring it to a high heat so that the oil bubbles rise from the inside out, then simmer it over a low heat. As the gas rises and swirls around the pot, occasionally dip a small amount into the pot and drip it into prepared cold water; the droplets will form beads.

[0040] E. Add 7 kg of litharge obtained in step C to the refined medicinal oil and stir constantly to ensure that the litharge reacts fully with the medicinal oil. Generally, the ratio is 195 g of litharge to 500 g of medicinal oil (16:7). However, the ratio may vary slightly depending on the season. More litharge is needed in summer and less in autumn and winter.

[0041] F. Remove the fire toxin: Quickly immerse the prepared paste in prepared cold water, change the water once a day, and let it sit for more than a week.

[0042] G. Adding fine ingredients: Add precious and fine medicines, such as camphor and borneol, to the melted plaster and stir continuously.

[0043] H. Pressing the plaster: Remove the cooked plaster from the heat, pick it up with bamboo chopsticks, place it on the prepared cloth, and use the bamboo chopsticks to press the center of the cloth and rotate it around to spread the plaster evenly. After the plaster cools and solidifies, it can be cut into pieces of appropriate size.

[0044] Example 2

[0045] A. Soak 50 parts of Curculigo orchioides, 30 parts of Epimedium, 50 parts of Drynaria fortunei, 50 parts of Broussonetia papyrifera, 50 parts of Eucommia ulmoides, 50 parts of Dipsacus asper, 25 parts of Paeonia lactiflora, 25 parts of Ligusticum chuanxiong, 25 parts of Angelica sinensis, 30 parts of Corydalis yanhusuo, 30 parts of Homalomena occulta, 15 parts of Eupolyphaga sinensis, 30 parts of Achyranthes bidentata, 30 parts of Artemisia argyi, 30 parts of Lycopodium clavatum, 30 parts of Clematis chinensis, 30 parts of Clematis armandii, 30 parts of Clematis chinensis ...15 parts of Notopterygium incisum, and 15 parts of Angelica pubescens in pre-prepared sesame oil. The ratio of medicine to oil should be 1:2, and the medicine should be thoroughly soaked.

[0046] B. Heat the soaked Chinese herbal medicine slices and medicinal oil from step A, stirring constantly to ensure even heating. First, use high heat, then low heat, until the herbs are golden brown or blackened. Once all the herbs float to the surface of the oil, remove the residue and filter out the remaining medicinal oil.

[0047] C. Put the litharge into the prepared iron pot and stir-fry repeatedly to remove the moisture from the litharge.

[0048] D. Place the medicinal oil obtained in step B into a pot. First, bring it to a high heat so that the oil bubbles rise from the inside out, then simmer it over a low heat. As the gas rises and swirls around the pot, occasionally dip a small amount into the pot and drip it into prepared cold water; the droplets will form beads.

[0049] E. Add 14 kg of litharge obtained in step C to the refined medicinal oil and stir constantly to allow the litharge and medicinal oil to react fully. Generally, the ratio is 195 g of litharge to 500 g of medicinal oil (16:7). However, the ratio may vary slightly depending on the season. More litharge is needed in summer and less in autumn and winter.

[0050] F. Remove the fire toxin: Quickly immerse the prepared paste in prepared cold water, change the water once a day, and let it sit for more than a week.

[0051] G. Adding fine ingredients: Add precious and fine medicines, such as camphor and borneol, to the melted plaster and stir continuously.

[0052] H. Pressing the plaster: Remove the cooked plaster from the heat, pick it up with bamboo chopsticks, place it on the prepared cloth, and use the bamboo chopsticks to press the center of the cloth and rotate it around to spread the plaster evenly. After the plaster cools and solidifies, it can be cut into pieces of appropriate size.

[0053] Example 3

[0054] A. Soak 70 parts of Curculigo orchioides, 50 parts of Epimedium, 70 parts of Drynaria fortunei, 70 parts of Broussonetia papyrifera, 70 parts of Eucommia ulmoides, 70 parts of Dipsacus asper, 40 parts of Paeonia lactiflora, 40 parts of Ligusticum chuanxiong, 40 parts of Angelica sinensis, 50 parts of Corydalis yanhusuo, 50 parts of Homalomena occulta, 20 parts of Eupolyphaga sinensis, 50 parts of Achyranthes bidentata, 50 parts of Artemisia argyi, 50 parts of Lycopodium clavatum, 50 parts of Clematis chinensis, 50 parts of Clematis armandii, 50 parts of Clematis chinensis ...20 parts of Notopterygium incisum, and 20 parts of Angelica pubescens in pre-prepared sesame oil. The ratio of medicine to oil should be 1:2, and the medicine should be thoroughly soaked.

[0055] B. Heat the soaked Chinese herbal medicine slices and medicinal oil from step A, stirring constantly to ensure even heating. First, use high heat, then low heat, until the herbs are golden brown or blackened. Once all the herbs float to the surface of the oil, remove the residue and filter out the remaining medicinal oil.

[0056] C. Put the litharge into the prepared iron pot and stir-fry repeatedly to remove the moisture from the litharge.

[0057] D. Place the medicinal oil obtained in step B into a pot. First, bring it to a high heat so that the oil bubbles rise from the inside out, then simmer it over a low heat. As the gas rises and swirls around the pot, occasionally dip a small amount into the pot and drip it into prepared cold water; the droplets will form beads.

[0058] E. Add 25 kg of litharge obtained in step C to the refined medicinal oil and stir constantly to allow the litharge and medicinal oil to react fully. Generally, the ratio is 195 g of litharge to 500 g of medicinal oil (16:7). However, the ratio may vary slightly depending on the season. More litharge is needed in summer and less in autumn and winter.

[0059] F. Remove the fire toxin: Quickly immerse the prepared paste in prepared cold water, change the water once a day, and let it sit for more than a week.

[0060] G. Adding fine ingredients: Add precious and fine medicines, such as camphor and borneol, to the melted plaster and stir continuously.

[0061] H. Pressing the plaster: Remove the cooked plaster from the heat, pick it up with bamboo chopsticks, place it on a prepared cloth, and use the bamboo chopsticks to press the center of the cloth and rotate it around to spread the plaster evenly. After the plaster cools and solidifies, it can be cut into pieces of appropriate size.

[0062] Example 4

[0063] A. Soak 80 parts of Curculigo orchioides, 60 parts of Epimedium, 80 parts of Drynaria fortunei, 80 parts of Broussonetia papyrifera, 80 parts of Eucommia ulmoides, 80 parts of Dipsacus asper, 50 parts of Paeonia lactiflora, 50 parts of Ligusticum chuanxiong, 50 parts of Angelica sinensis, 60 parts of Corydalis yanhusuo, 60 parts of Homalomena occulta, 30 parts of Eupolyphaga sinensis, 60 parts of Achyranthes bidentata, 60 parts of Artemisia argyi, 60 parts of Lycopodium clavatum, 60 parts of Clematis chinensis, 60 parts of Clematis armandii, 60 parts of Clematis chinensis ...30 parts of Notopterygium incisum, and 30 parts of Angelica pubescens in pre-prepared sesame oil. The ratio of medicine to oil should be 1:2, and the medicine should be thoroughly soaked.

[0064] B. Heat the soaked Chinese herbal medicine slices and medicinal oil from step A, stirring constantly to ensure even heating. First, use high heat, then low heat, until the herbs are golden brown or blackened. Once all the herbs float to the surface of the oil, remove the residue and filter out the remaining medicinal oil.

[0065] C. Put the litharge into the prepared iron pot and stir-fry repeatedly to remove the moisture from the litharge.

[0066] D. Place the medicinal oil obtained in step B into a pot. First, bring it to a high heat so that the oil bubbles rise from the inside out, then simmer it over a low heat. As the gas rises and swirls around the pot, occasionally dip a small amount into the pot and drip it into prepared cold water; the droplets will form beads.

[0067] E. Add 32 kg of litharge obtained in step C to the refined medicinal oil and stir constantly to allow the litharge and medicinal oil to react fully. Generally, the ratio is 195 g of litharge to 500 g of medicinal oil (16:7). However, the ratio may vary slightly depending on the season. More litharge is needed in summer and less in autumn and winter.

[0068] F. Remove the fire toxin: Quickly immerse the prepared paste in prepared cold water, change the water once a day, and let it sit for more than a week.

[0069] G. Adding fine ingredients: Add precious and fine medicines, such as camphor and borneol, to the melted plaster and stir continuously.

[0070] H. Pressing the plaster: Remove the cooked plaster from the heat, pick it up with bamboo chopsticks, place it on a prepared cloth, and use the bamboo chopsticks to press the center of the cloth and rotate it around to spread the plaster evenly. After the plaster cools and solidifies, it can be cut into pieces of appropriate size.

[0071] Clinical observation of the efficacy of this invention in treating chronic neck, shoulder, back and leg pain:

[0072] The study included 80 patients with chronic neck, shoulder, back, and leg pain who visited our department between June 2020 and June 2023. All patients presented with persistent pain at the time of their visit. Among them, 35 were male and 45 were female, with ages ranging from 21 to 84 years (mean age 52 years). The duration of their illness ranged from six months to 20 years (mean duration 5 years). None of the patients had impairments in cognitive ability, intelligence, or organic lesions. Patients were divided into experimental and control groups according to their treatment plans. There were no significant differences in baseline data between the groups (P > 0.05), indicating comparability.

[0073] Treatment methods:

[0074] Experimental group: Patients in this group used the herbal plaster of this invention for external application treatment, changing the plaster daily, applying it for 7-8 hours each time, and the course of treatment was four weeks.

[0075] Control group: Patients in this group applied Compound Nanxing Analgesic Plaster (produced by Jiangsu Kangyuan Sunshine Pharmaceutical Co., Ltd.) to the affected area for 4-6 hours per plaster, with a course of treatment of four weeks.

[0076] The numerical pain score was used to assess the severity of chronic neck, shoulder, back, and leg pain in patients; higher scores indicated more severe pain. The Student's Life Quality-36 (SF-36) scale was used to assess patients' quality of life; higher scores indicated a higher quality of life. The total pain scores and SF-36 scores of both groups were observed and recorded before and after treatment.

[0077] Statistical methods: SPSS 19.0 software was used for statistical analysis of clinical data. Count data were presented as percentages (%) and analyzed using a chi-square test. Measurement data, such as patient pain levels (1) and quality of life scores (2) before and after the experiment, were presented as linear data and analyzed using t-tests. A p-value < 0.05 was considered statistically significant between groups.

[0078] Treatment results:

[0079] Comparison of total pain scores before and after treatment between the two groups: Before the experiment, there was no significant difference in total pain scores between the two groups (P>0.05). After the experiment, the total pain scores of both groups decreased compared to before the experiment (P<0.05), with the experimental group showing better total pain scores than the control group (P<0.05). Detailed data are shown in Table 1 below.

[0080] Comparison of changes in total quality of life scores before and after treatment between the two groups: Before the experiment, there was no significant difference in total quality of life scores between the two groups (P > 0.05). After the experiment, the total quality of life scores of both groups improved compared to before the experiment (P < 0.05), with the experimental group showing significantly higher total quality of life scores than the control group (P < 0.05). Detailed data are shown in Table 2 below.

[0081] Table 1 Comparison of total pain scores before and after treatment between the two groups of patients with chronic neck, shoulder, back and leg pain.

[0082]

[0083] Group Number of examples Before the experiment After the experiment experimental group 40 8.05±5.85 3.15±3.30 control group 40 7.87±4.04 5.41±3.98 t-value 0.0228 2.4980 p-value 0.9818 0.0146

[0084] Table 2 Comparison of changes in total quality of life scores before and after treatment between the two groups of patients with chronic neck, shoulder, back and leg pain.

[0085] Group Number of examples Before the experiment After the experiment experimental group 40 71.05±3.0 115.80±9.15 control group 40 69.06±4.80 80.05±6.02 t-value 0.3242 3.1680 p-value 0.7466 0.0022

[0086] The following are 16 case studies of patients seeking medical treatment:

[0087] 1. Neck pain

[0088] Mr. Hu, male, 39 years old, occupation: accountant. Date of consultation: October 17, 2020. Location: Baiyun Campus of Guangdong University of Technology and Teacher Education, Jianggao Town, Baiyun District, Guangzhou, Guangdong Province.

[0089] The patient complains of neck pain, accompanied by pain in the upper inner angle of the right scapula, for nearly a year. In October 2020, the patient fell off a bicycle and experienced neck pain accompanied by pain in the right upper arm, which recurred repeatedly and has not healed to this day. A hospital in Guangzhou diagnosed the patient with cervical spondylosis. Medication and traction provided some relief, but the pain persists. Currently, the patient presents with a sallow complexion, fatigue, poor sleep, normal bowel movements, a dark red tongue with a thin white coating, and a wiry, thready pulse.

[0090] Traditional Chinese Medicine Diagnosis: Cervical Bi Syndrome

[0091] Apply this plaster to the painful area. Use one plaster daily for 15 days. The patient reported improvement in neck pain. Continue applying the plaster for another 15 days to consolidate the effect. During a one-year follow-up, the symptoms were basically relieved.

[0092] 2. Low back pain

[0093] Mr. Ouyang, male, 53 years old. Date of visit: June 18, 2020. Address: Room 702, No. 55, Fazheng Road, Yuexiu District, Guangzhou.

[0094] The patient complained of recurrent lower back pain for one year, which worsened in the past week.

[0095] Present illness: One year ago, the patient developed lower back pain without any obvious cause. The pain worsened after exertion or prolonged sitting or standing, without radiating pain in the lower limbs. Current symptoms: fatigue, lower back pain and soreness, intolerance to exertion, limited range of motion in bending and stretching, pale complexion, moderate build, dark red tongue with a thin white coating, dark purple and tortuous sublingual veins, and a wiry and thready pulse.

[0096] Traditional Chinese Medicine Diagnosis: Lumbar Bi (a traditional Chinese medicine term for lumbar pain)

[0097] Apply this plaster to the painful area. Use one plaster daily for 14 days. At the follow-up visit, the lower back pain was significantly improved, and the symptoms of lower back soreness were alleviated. Continue applying the plaster for another 14 days to consolidate the effect. During the one-year follow-up, the symptoms were basically relieved.

[0098] 3. Shoulder pain

[0099] Ms. Xu, female, 22 years old, date of consultation: September 8, 2019. Guangzhou Normal University, Tianhe District.

[0100] The patient complains of right shoulder pain for nearly 10 months, caused by prolonged work in an air-conditioned room with the air conditioner vent pointing directly at the right shoulder. Gradually, this has led to difficulty raising the right shoulder and extending it backward, especially at night. The tongue is red with a thin white coating, and the pulse is wiry.

[0101] Traditional Chinese Medicine Diagnosis: Shoulder Pain

[0102] The plaster of this invention was applied and changed once a day. After two weeks, a follow-up visit showed that the symptoms had not recurred since the application of the plaster.

[0103] 4. Low back pain

[0104] Ms. Deng, 53 years old, date of consultation: March 6, 2019. Address: No. 33, Huanshi West Road, Yuexiu District, Guangzhou.

[0105] The patient complained of soreness and discomfort in the right lower back and buttocks for more than a year. A year ago, the patient went on a road trip and experienced the above symptoms due to the bumpy ride and prolonged sitting. The symptoms did not improve significantly after rest, and have worsened in the past month due to fatigue.

[0106] Traditional Chinese Medicine Diagnosis: Lumbar Bi (a traditional Chinese medicine term for lumbar pain)

[0107] After applying the plaster of this invention and changing it once a day, the soreness in the right buttock was significantly reduced after two weeks, and the right waist occasionally felt sore and swollen after sitting for a long time.

[0108] 5. Neck pain

[0109] Mr. Ou, male, 63 years old, date of consultation: December 5, 2018. Sanyuanli, Baiyun District, Guangzhou City.

[0110] The patient complained of neck tightness and discomfort for more than 10 years, occasionally accompanied by dizziness, which worsened after working at a desk and was not significantly relieved after rest. She also had poor sleep, difficulty falling asleep, and was easily awakened. She had a history of primary hypertension and hyperlipidemia for many years and had been taking medication to control them.

[0111] Traditional Chinese Medicine Diagnosis: Cervical Bi Syndrome

[0112] After applying the plaster of this invention and changing it once a day, the tightness in the neck was relieved after two weeks, and the dizziness did not recur. I asked the doctor to prescribe a few more plasters for later use.

[0113] 6. Low back pain

[0114] Ms. Chen, female, 60 years old, date of consultation: October 12, 2017. Address: No. 2, Ganliwuchang Village, Xinbao Town, Xinyi City, Guangdong Province.

[0115] The patient complained of lower back and hip pain for more than two years after sitting for a long time. The symptoms were slightly relieved after applying heat or engaging in physical activity, but worsened after exposure to cold. The pain was severe at night, affecting sleep, and the symptoms gradually became more serious.

[0116] Traditional Chinese Medicine Diagnosis: Lumbar Bi (a traditional Chinese medicine term for lumbar pain)

[0117] Apply the plaster of this invention, changing it once a day. After two weeks, the lower back and hip pain has been reduced, and sleep at night is improved. Prescribe another 10 plasters to consolidate the therapeutic effect.

[0118] 7. Shoulder pain

[0119] Ms. Liu, 69 years old, date of visit: September 6, 2016. Room 501, No. 5, Jiren Lane, Yuexiu District, Guangzhou.

[0120] The patient complained of recurrent pulling pain in the right neck and inner side of the scapula for more than a year. The pain in the right shoulder worsened when looking down at a mobile phone for a long time or when exposed to cold. The pain was severe at night and affected sleep.

[0121] Traditional Chinese Medicine Diagnosis: Shoulder Pain

[0122] Apply the plaster of this invention and change it once a day. After two weeks, the pain in the right shoulder will be significantly relieved, and you can sleep peacefully at night. Keep the plaster with you for future use.

[0123] 8. Low back pain

[0124] Huang Moumin, male, 29 years old, born on March 5, 2016. No. 9, Lane 9, Zhengjieyuan, Dalang Village, Baiyun District, Guangzhou City.

[0125] Patient complains of recurrent right-sided lower back and leg pain for 3 years, which worsens after prolonged sitting or heavy lifting and is slightly relieved when lying flat. An MRI showed a central protrusion of the right side of the L4 / L5 intervertebral disc and stenosis of the right recess.

[0126] Traditional Chinese Medicine Diagnosis: Lumbar Bi (a traditional Chinese medicine term for lumbar pain)

[0127] Apply the plaster of this invention and change it once a day. After two weeks, the pain in the right lower back and leg will be relieved. The pain will not be obvious when you wake up in the morning. Keep the plaster with you for future use.

[0128] 9. Neck pain

[0129] Chen Mouhua, female, 50 years old, born on June 9, 2015. Room 502, No. 8-1, Fujin East Road, Yuexiu District, Guangzhou.

[0130] The patient complained of soreness and discomfort in the left side of the neck, shoulder, and back for more than half a year. The pain was worse at night, especially when lying on the left side. The patient also experienced numbness and swelling in both hands, with the left hand being particularly affected.

[0131] Traditional Chinese Medicine Diagnosis: Cervical Bi Syndrome

[0132] The patient applied the plaster of this invention and changed it once a day. After two weeks, the patient returned for a follow-up visit and reported that the soreness in the left neck, shoulder and back had been significantly relieved and the numbness and swelling in the right hand had disappeared. The patient was advised to keep the plaster with them for future use.

[0133] 10. Low back pain

[0134] Tang Mou-dong, male, 53 years old, born on March 16, 2015. 3rd Floor, No. 10-1, Houfu New Street, Liwan District, Guangzhou.

[0135] Complaint: I have been experiencing soreness and discomfort in my lumbosacral region for nearly 2 years after sitting for a long time. It has worsened in the past month and is slightly relieved after activity. I cannot sleep in a flat position at night, and it hurts when I turn over in bed. Applying heat can reduce the pain.

[0136] Traditional Chinese Medicine Diagnosis: Lumbar Bi (a traditional Chinese medicine term for lumbar pain)

[0137] Apply the plaster of this invention and change it once a day. After two weeks, the symptoms will be greatly relieved. You can lie flat to sleep in the first half of the night and turn over in bed without pain. Keep the plaster with you for future use.

[0138] 11. Neck pain

[0139] Zhang Mouling, female, 43 years old, born on September 6, 2014. No. 56, Wanggou Group, Xiangbei Village, Xianghua Town, Xichuan County, Henan Province.

[0140] The patient complained of recurrent soreness, numbness, swelling and discomfort in the neck and back for more than a year, with limited mobility. She also experienced occasional postural vertigo and had undergone manual repositioning for benign paroxysmal positional vertigo, but the symptoms still recurred from time to time.

[0141] Traditional Chinese Medicine Diagnosis: Cervical Bi Syndrome

[0142] After applying the plaster of this invention and changing it once a day for two weeks, the numbness and swelling in the neck and back were significantly reduced, and postural vertigo did not recur.

[0143] 12. Low back pain

[0144] Ms. Xu, 57 years old, date of consultation: September 2, 2013. Address: XX Garden, Baiyun District, Guangzhou.

[0145] The patient complained of recurrent lumbosacral pain and discomfort for more than 3 years, which worsened after prolonged sitting, standing, or walking and was relieved when lying flat. An MRI showed a bulging disc at L5 / S1.

[0146] Traditional Chinese Medicine Diagnosis: Lumbar Bi (a traditional Chinese medicine term for lumbar pain)

[0147] Apply the plaster of this invention and change it once a day. After two weeks, the original symptoms will be significantly relieved. Then, apply the plaster for another two weeks to consolidate the therapeutic effect.

[0148] 13. Low back pain

[0149] Ms. Zhang, 48 years old, date of consultation: July 2, 2012. Address: Nanhang Biyuan Garden, Shanqian Avenue, Shiling Town, Huadu District, Guangzhou City.

[0150] The patient complained of lower back pain when standing or bending over for nearly two years, which worsened after doing housework such as washing vegetables, cooking, and washing dishes. The painful area was relieved by warmth and pressure.

[0151] Traditional Chinese Medicine Diagnosis: Lumbar Bi (a traditional Chinese medicine term for lumbar pain)

[0152] The patient applied the plaster of this invention, changing it once a day. After two weeks, the patient returned for a follow-up visit and reported that the symptoms had significantly improved. The patient was advised to keep the plaster with them for future use.

[0153] 14. Low back pain

[0154] Yang Mouhua, male, 44 years old, date of consultation: October 12, 2011. Address: Room 701, No. 12 Yingxiang Road, Haizhu District, Guangzhou.

[0155] The patient complained of stiffness and discomfort in her lower back for 3 years. She had sprained her lower back while playing sports 3 years ago and was treated conservatively, but the stiffness and discomfort in her lower back remained. The symptoms were especially noticeable in the morning or after sitting for a long time.

[0156] Traditional Chinese Medicine Diagnosis: Lumbar Bi (a traditional Chinese medicine term for lumbar pain)

[0157] The patient applied the plaster of this invention and changed it once a day. After two weeks, the patient returned for a follow-up visit and reported that the stiffness and discomfort in the lower back had been greatly relieved. The patient was then prescribed another two weeks of plaster to consolidate the therapeutic effect.

[0158] 15. Neck pain

[0159] Ms. Huang, female, 30 years old, date of consultation: June 9, 2011. Address: Room 2402, Building 5, Zhongcun Qifu Mingdu, Zhongcun Subdistrict, Panyu District, Guangzhou City, Guangdong Province.

[0160] The patient complained of neck pain accompanied by recurrent dizziness and headache for 5 years, which worsened after exertion. Each episode of dizziness and headache lasted about 2 to 3 days and often occurred before menstruation. Occasionally, there was transient blurred vision and temporary blackouts in front of the eyes.

[0161] Traditional Chinese Medicine Diagnosis: Cervical Bi Syndrome

[0162] The patient applied the plaster of this invention and changed it once a day. Two weeks later, at the follow-up visit, the patient reported that the neck pain had been greatly relieved and that there was no dizziness or headache. The patient was advised to keep the plaster with them for future use.

[0163] 16. Low back pain

[0164] Mr. Lin, male, 78 years old, date of consultation: May 7, 2010. Fuli Taoyuan, Baiyun District, Guangzhou.

[0165] The patient complained of lower back and hip pain accompanied by weakness in the right lower limb for 5 years, with symptoms significantly worsening after prolonged walking and relieved by sitting. A previous MRI revealed multi-segmental lumbar disc herniation or bulging, thickening of the ligamentum flavum, and secondary spinal stenosis in the corresponding segments.

[0166] Traditional Chinese Medicine Diagnosis: Lumbar Bi (a traditional Chinese medicine term for lumbar pain)

[0167] The patient applied the plaster of this invention and changed it once a day. After two weeks, the patient returned for a follow-up visit and reported that the pain in the lower back and buttocks had been reduced and that walking was painless. The patient was then prescribed another two weeks of plaster to consolidate the therapeutic effect.

[0168] The above description is merely a preferred embodiment of the present invention and is not intended to limit the invention. Various modifications and variations can be made to the invention by those skilled in the art. Any modifications, equivalent substitutions, or improvements made within the spirit and principles of the invention should be included within the scope of protection of the invention.

Claims

1. A plaster for treating chronic neck, shoulder, back, and leg pain, characterized in that, The product is prepared from the following raw materials by weight: 20-80 parts of Curculigo orchioides, 15-60 parts of Epimedium, 20-80 parts of Drynaria fortunei, 20-80 parts of Broussonetia papyrifera, 20-80 parts of Eucommia ulmoides, 20-80 parts of Dipsacus asper, 10-50 parts of Paeonia lactiflora, 10-50 parts of Ligusticum chuanxiong, 10-50 parts of Angelica sinensis, 15-60 parts of Corydalis yanhusuo, 15-60 parts of Homalomena occulta, 5-30 parts of Eupolyphaga sinensis, 15-60 parts of Pterocarya stenoptera, 15-60 parts of Achyranthes bidentata, 15-60 parts of Artemisia argyi, 15-60 parts of Lycopodium clavatum, 15-60 parts of Clematis chinensis, 15-60 parts of Clematis armandii, 15-60 parts of Clematis chinensis, 15-60 parts of Clematis chinensis, 15-60 parts of Clematis chinensis, 15-60 parts of Clematis chinensis, 15-60 parts of Geranium wilfordii, 15-60 parts of Pyrola rotundifolia, 5-30 parts of Notopterygium incisum, and 5-30 parts of Angelica pubescens.

2. The plaster for treating chronic neck, shoulder, back and leg pain according to claim 1, characterized in that, It is prepared from the following raw materials: 25-75 parts of Curculigo orchioides, 20-55 parts of Epimedium, 25-75 parts of Drynaria fortunei, 25-75 parts of Broussonetia papyrifera, 25-75 parts of Eucommia ulmoides, 25-75 parts of Dipsacus asper, 15-45 parts of Paeonia lactiflora, 15-45 parts of Ligusticum chuanxiong, 15-45 parts of Angelica sinensis, 20-55 parts of Corydalis yanhusuo, 20-55 parts of Homalomena occulta, 10-25 parts of Eupolyphaga sinensis, 20-55 parts of Pterocarya stenoptera, 20-55 parts of Achyranthes bidentata, 20-55 parts of Artemisia argyi, 20-55 parts of Lycopodium clavatum, 20-55 parts of Clematis chinensis, 20-55 parts of Clematis armandii, 20-55 parts of Clematis chinensis, 20-55 parts of Clematis chinensis, 20-55 parts of Clematis chinensis, 20-55 parts of Geranium wilfordii, 20-55 parts of Pyrola rotundifolia, 10-25 parts of Notopterygium incisum, and 10-25 parts of Angelica pubescens.

3. A method for preparing a plaster for treating chronic neck, shoulder, back, and leg pain according to any one of claims 1 or 2, characterized in that, Includes the following steps: A. Soaking: Soak each ingredient in the prepared sesame oil in a ratio of 1:2, ensuring thorough soaking. B. Explosives: Heat the soaked Chinese medicinal herbs and medicinal oil from step A, stirring constantly to ensure even heating. First, use high heat, then low heat, until the herbs are golden brown or blackened. Once all the herbs float to the surface of the oil, remove the residue and filter out the residue, leaving only the medicinal oil. C. Stir-frying the litharge: Put the litharge into a prepared iron pot and stir-fry repeatedly to remove the moisture from the litharge; D. Refining the oil: Put the medicinal oil obtained in step B into a pot, first use high heat to make the oil bubbles rise from the inside to the outside, then use low heat to refine the oil in the pot. When the gas rises around the pot, occasionally dip a little and drip it into the prepared cold water. The water droplets will form beads. E. Adding the lead oxide: Add 7-40 kg of lead oxide obtained in step C to the refined medicinal oil, stirring constantly to ensure that the lead oxide and the medicinal oil react fully. Generally, 195 g of lead oxide is added for every 500 g of medicinal oil. F. Remove the fire toxin: Quickly immerse the refined paste in prepared cold water, change the water once a day, and let it sit for more than a week; G. Add fine ingredients: Add camphor and borneol to the melted plaster and stir constantly; H. Pressing the plaster: Remove the cooked plaster from the heat, pick it up with bamboo chopsticks, place it on the prepared cloth, and use the bamboo chopsticks to press the center of the cloth and rotate it around to spread the plaster evenly. After the plaster cools and solidifies, it can be cut into pieces of appropriate size.

4. A method for preparing a plaster for treating chronic neck, shoulder, back, and leg pain according to claim 3, characterized in that, The weight range of the sesame oil in step A is 0.6-6 kg.

5. A method for preparing a plaster for treating chronic neck, shoulder, back, and leg pain according to claim 3, characterized in that, The oil temperature range for extracting the medicinal materials in step B is 200-220℃.

6. A method for preparing a plaster for treating chronic neck, shoulder, back, and leg pain according to claim 3, characterized in that, The weight range of litharge in step C is 7-40 kg.

7. A method for preparing a plaster for treating chronic neck, shoulder, back, and leg pain according to claim 3, characterized in that, The oil temperature range during refining in step D is 200-300℃.

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