A kind of insecticide composition containing trifluanid and its application

Abstract

The present invention belongs to the field of pesticide insecticide technology and discloses an insecticidal composition containing trifluanid and its application. The active ingredients in the insecticidal composition include active ingredient A and active ingredient B, wherein active ingredient A is trifluanid and active ingredient B is either bifenthrin or isoxathiapiprolin. The mass ratio of active ingredient A to active ingredient B is 1:50 to 30:1. The insecticidal composition has excellent control effects on various crop pests. Due to the emergence of pests resistant to existing drugs, this application develops a new type of agricultural and horticultural insecticide.

Description

Technical Field

[0001] The invention belongs to the technical field of pesticide killing, and discloses an insecticidal composition containing trifluanid and application thereof. Background Art

[0002] Triflumezopyrim, also known internationally as triflumezopyrim and in Chinese as 2,4-dioxy-1-(5-pyrimidinylmethyl)-3-[3-(trifluoromethyl)phenyl]-3,4-dihydro-2H-pyrido[1,2-a]pyrimidin-1-cation-3-carbanion, has a CAS number of 1263133-33-0. Triflumezopyrim is a competitive modulator of nicotinic acetylcholine receptors (nAChRs) that acts on the insect nervous system. Binding to the acetylcholine site on the nAChRs, it induces a range of symptoms in insects, from hyperexcitability to lethargy and paralysis. Acetylcholine is the primary excitatory neurotransmitter in the insect central nervous system. Triflumezopyrim is effective against pests such as rice planthoppers that have developed resistance to neonicotinoid insecticides.

[0003] Bifenthrin, commonly known as bifenthrin, CAS number: 82657-04-3, acts on the nervous system of insects by disrupting their function through the action of sodium ion channels. Bifenthrin is a pyrethroid insecticide and acaricide with contact and stomach properties. It has a broad spectrum of insecticides, acts rapidly, is immobilized in soil, and is relatively safe for the environment with a long-lasting effect.

[0004] Isocycloseramide, commonly known as isocycloseram and CAS number 2061933-85-3, has a novel mechanism of action. It is an allosteric modulator of γ-aminobutyric acid (GABA)-gated chloride channels, disrupting the normal conduction of insect nerve impulses, leading to hyperexcitement and convulsions. This compound has a broad insecticide spectrum, effectively controlling Lepidoptera, Hemiptera, Coleoptera, Thysanoptera, Diptera pests, and mites. It is also safe for pollinators such as bees and can be used on crops such as cotton, vegetables, fruits, and corn, as well as cash crops such as tobacco.

[0005] Chemical control is the primary method for agricultural pest control. The use of a single pesticide is often limited by factors such as efficacy, scope of application, and potential for harmful effects. Furthermore, as pest resistance develops, control effectiveness gradually decreases. To overcome the shortcomings of single pesticides, the rational blending of pesticides of different types and modes of action can improve control effectiveness, reduce dosage, and lower labor costs. Summary of the Invention

[0006] To address the aforementioned problems existing in the prior art, the present invention provides an insecticide composition containing trifluanid. This insecticide composition exhibits excellent control efficacy against a variety of agricultural, horticultural, and forestry pests, reduces pesticide dosage, and slows the development of pest resistance. Furthermore, the present invention provides the use of this insecticide composition for controlling Hemiptera pests.

[0007] In order to achieve the above object, the present invention adopts the following technical solution: an insecticidal composition containing trifluanid, wherein the active ingredients in the insecticidal composition include active ingredient A and active ingredient B, the active ingredient A is trifluanid, the active ingredient B is any one of bifenthrin or isoxathiapyr, and the mass ratio of the active ingredient A to the active ingredient B is 1:50 to 30:1, or any value within the above numerical range.

[0008] Furthermore, the active ingredient B is bifenthrin, and the mass ratio of the active ingredient A to the active ingredient B is 1:50 to 15:1, or any value within the above numerical range;

[0009] Furthermore, the active ingredient B is bifenthrin, and the mass ratio of the active ingredient A to the active ingredient B is 1:50, 1:35, 1:15, 1:5, 1:2, 1:1, 2:1, 5:1, and 15:1;

[0010] Furthermore, the active ingredient B is isoxathiapiprole, and the mass ratio of the active ingredient A to the active ingredient B is 1:30 to 30:1, or any value within the above numerical range;

[0011] Furthermore, the active ingredient B is isoxathiapiprolin, and the mass ratio of the active ingredient A to the active ingredient B is 1:30; 1:20, 1:10, 1:5, 5:1, 10:1, 20:1, 30:1;

[0012] Furthermore, the active ingredient B is bifenthrin, and the mass ratio of the active ingredient A to the active ingredient B is 1:35 to 5:1, or any value within the above numerical range;

[0013] Furthermore, the active ingredient B is bifenthrin, and the mass ratio of the active ingredient A to the active ingredient B is 1:35, 1:15, 1:5, 1:2, 1:1, 2:1, and 5:1;

[0014] Furthermore, the active ingredient B is isoxathiapiprolin, and the mass ratio of the active ingredient A to the active ingredient B is 1:20 to 20:1, or any value within the above numerical range;

[0015] Furthermore, the active ingredient B is isoxathiapiprole, and the mass ratio of the active ingredient A to the active ingredient B is 1:20, 1:10, 1:5, 5:1, 10:1, and 20:1;

[0016] Furthermore, the total weight of the insecticide composition is 100 wt%, and the total weight of the active ingredient A and the active ingredient B accounts for 0.2% to 75% of the total weight of the insecticide composition;

[0017] Furthermore, the total weight of the insecticide composition is 100 wt%, and the total weight of the active ingredient A and the active ingredient B accounts for 1% to 60% of the total weight of the insecticide composition;

[0018] Furthermore, the insecticide composition further comprises auxiliary ingredients in addition to the active ingredient, and the active ingredient is selected from one or more of a wetting agent, a dispersant, an emulsifier, a thickener, a disintegrant, an antifreeze agent, a defoaming agent, a preservative, a stabilizer, a synergist or a carrier;

[0019] The wetting agent is selected from one or more of alkylbenzene sulfonate, alkylnaphthalene sulfonate, lignin sulfonate, sodium lauryl sulfate, sodium dioctyl sulfosuccinate, α-olefin sulfonate, alkylphenol polyoxyethylene ether, castor oil polyoxyethylene ether, alkylphenol ethoxylate, fatty alcohol ethoxylate, fatty alcohol polyoxyethylene ether sodium sulfate, silkworm feces, soapberry powder, soapberry powder, SOPA, detergent, emulsifier 2000 series and wetting penetrant F; and / or

[0020] The dispersant is selected from one or more of lignin sulfonate, alkylnaphthalene sulfonate formaldehyde condensate, naphthalene sulfonate, tristyrylphenol ethoxylate phosphate, fatty alcohol ethoxylate, alkylphenol polyoxyethylene ether, alkylphenol polyoxyethylene ether methyl ether condensate sulfate, fatty amine polyoxyethylene ether, glycerol fatty acid ester polyoxyethylene ether, polycarboxylates, polyacrylic acids, phosphates, EO-PO block copolymers and EO-PO graft copolymers; and / or

[0021] The emulsifier is selected from one or more of calcium dodecylbenzenesulfonate, alkylphenol formaldehyde resin polyoxyethylene ether, phenylethylphenol polyoxyethylene polyoxypropylene ether, fatty alcohol ethylene oxide-propylene oxide copolymer, styrylphenol polyoxyethylene ether, castor oil polyoxyethylene ether and alkylphenol ether phosphate; and / or

[0022] The thickener is selected from one or more of xanthan gum, organobentonite, gum arabic, sodium alginate, magnesium aluminum silicate, carboxymethyl cellulose and white carbon black; and / or

[0023] Disintegrants: The disintegrants are selected from one or more of sodium sulfate, ammonium sulfate, aluminum chloride, sodium chloride, ammonium chloride, bentonite, glucose, sucrose, starch, cellulose, urea, sodium carbonate, sodium bicarbonate, citric acid and tartaric acid; and / or

[0024] The antifreeze agent is selected from one or more of alcohols, alcohol ethers, chlorinated hydrocarbons and inorganic salts; and / or

[0025] Defoaming agent selected from C 10 -C 20 Saturated fatty acid compounds, silicone oil, silicone compounds, C8-C 10 One or more of fatty alcohols; and / or

[0026] The solvent is selected from one or more of benzene, toluene, xylene, durene, methanol, ethanol, isopropanol, n-butanol, dimethyl sulfoxide, dimethylformamide, cyclohexanone, alkylene carbonate, diesel, solvent oil, vegetable oil, vegetable oil derivatives and water; and / or

[0027] The preservative is selected from one or more of propionic acid, sodium propionic acid, sorbic acid, sodium sorbic acid, potassium sorbic acid, benzoic acid, sodium benzoic acid, sodium p-hydroxybenzoic acid, methyl p-hydroxybenzoate, kasone and 1,2-benzisothiazolin-3-one; and / or

[0028] The stabilizer is selected from one or more of disodium hydrogen phosphate, oxalic acid, succinic acid, adipic acid, borax, 2,6-di-tert-butyl-p-cresol, triethanolamine oleate, epoxidized vegetable oil, kaolin, bentonite, attapulgite, white carbon black, talc, montmorillonite and starch; and / or

[0029] Synergists are selected from synergist, piperonyl butoxide; and / or

[0030] The carrier is selected from one or more of ammonium salts, ground natural minerals, ground artificial minerals, silicates, resins, waxes, solid fertilizers, water, organic solvents, mineral oils, vegetable oils and vegetable oil derivatives;

[0031] Furthermore, the formulation of the insecticide composition is a solid preparation or a liquid preparation;

[0032] Furthermore, the solid preparation includes powders, granules, pellets, tablets, strips, wettable powders, oil-dispersible powders, emulsion powders, water-dispersible granules, emulsion granules, water-dispersible tablets, soluble powders, soluble tablets or soluble granules;

[0033] The liquid preparations include soluble solutions, soluble gels, oils, film-spreading oils, emulsifiable concentrates, latexes, dispersible solutions, ointments, aqueous emulsions, oil emulsions, microemulsions, lipid suspensions, microcapsule suspensions, oil suspensions, dispersible oil suspensions, suspoemulsions, microcapsule suspension-suspension concentrates, microcapsule suspension-water emulsions, or microcapsule suspension-suspoemulsions;

[0034] Furthermore, the formulation is in the form of a suspension, emulsifiable concentrate, microemulsion, aqueous emulsion, dispersible oil suspension, wettable powder, or water-dispersible granules.

[0035] The present invention also discloses the use of the insecticide composition for preventing and controlling agricultural pests.

[0036] Furthermore, the pests are Hemiptera pests;

[0037] The Hemiptera pests include, but are not limited to, stink bugs: Acrosternum hilare (green stink bug), Blissus leucopterus (chinch bug), Calocoris norvegicus (potato mirid), Cimex hemipterus (tropical bed bug), Cimex lectularius (bed hug), Daghertus fasciatus, Dichelops furcatus, Dysdercus suturellus (cotton stainer), Edessa meditabunda, Eurygaster maura (cereal bug), Euschistus heros, Euschistus servus (brown stink bug), Helopeltis antonii, Helopeltis theivora (tea blight plant bug), Lagynotomus spp. (stink bugs), Leptocorisa oratorius, Leptocorisa varicornis, Lygus spp. (plant bugs), Lygus hesperus (western tarnished plant bug), Maconellicoccus hirsutus, Neurocolpus longirostris, Nezara viridula (southern green stink bug), PhyLocoris spp.) (lygus), Phytocoris californicus, Phytocoris relativus, Piezodorus guildingi, Poecilocapsus lineatus (fourlined plant bug), Psallus vaccinicola, Pseudacysta perseae, Scaptocoris castanea, and Triatoma spp. (bloodsucking conenoses / kissing bugs), Acrythosiphonpisum (pea aphid), Adelges spp. (adelgids), Aleurodes proletella (cabbage whitefly), Aleurodicus disperses, Aleurothrixus flccosus (woolly whitefly) (whitefly), Aluacaspis spp., Amrasca bigutella bigutella, Aphrophora spp. (leahopper), Aonidiella aurantii (California redscale), Aphis spp. (aphids), Aphis gossypii (cotton aphid), Aphis pomi (apple aphid), Aulacorthitm solani (foxglove aphid), Bemisia spp. (whitefly), Bemisia argentifolii, Bemisia tabaci (sweetpotato whitefly), Brachycolus noxius (Russian aphid), aphid), Brachycorynclia asparagi (asparagus aphid), Brevennia rehi, Brevicoryne brassicae (cabbage aphid), Ceroplastes spp.) (scale), Ceroplastes rubens (red wax scale), Chionaspis spp. (scale), Chrysomphalus spp. (scale), Coccus spp. (scale), Dysaphis plantaginea (rosy apple aphid), Empoasca spp. (leafhopper), Eriosomalanigerum (woolly apple aphid), Icerya purchasi (cottony cushion scale), Idioscopus nitidulus (mango leafhopper), Laodelphax striatellus (smaller brown planthopper), Lepidosaphes spp., Macrosiphum spp.), Macrosiphum euphorbiae (potato aphid), Macrosiphum granarium (English grain aphid), Macrosiphum rosae (rose aphid), Macrosteles quadrilineatus (asterleafhopper), Mahanarva frimbiolata, Metopolophium dirhodum (rose grain aphid), Midis longicornis, Myzus persicae (green peach aphid), Nephotettix spp.) (leafhopper), Nephotettix cinctipes (green leafhopper), Nilaparvata lugens (brown planthopper), Parlatoria pergandii (chaff scale), Parlatoria ziziphi (ebonyscale), Peregrinus maidis (corndelphacid), Philaenus spp. (blowing insects), Phylloxera vitifoliae (grape phylloxera), Physokermes piceae (spruce budscale), Planococcus spp. (mealybugs), Pseudococcus spp. (mealybugs), Pseudococcus brcvipcs (pinc apple mealybugs) mcalybug), Quadraspidiotus perniciosus (San Jose scale), Rhapalosiphum spp. (aphids), Rhapalosiphum maida (corn leaf aphid), Rhapalosiphum padi (oatbird-cherry aphid), Saissetia spp. (scale), Saissetiaoleae (black scale), Schizaphis graminum (wheat aphid), Sitobion avenge (British wheat aphid), Sogatella furcifera (white-backed planthopper), Therioaphis spp. (aphids), Toumeyella spp. (scale), Toxoptera spp. (aphids), Trialeurodes spp.) (whitefly), Trialeurodes vaporariorum (greenhouse whitefly), Trialeurodes abutiloneus (bandedwing whitefly), Unaspis spp. (scale), Unaspis yanonensis (arrowhead scale), and Zulia entreriana.

[0038] In particular, the pesticide composition of the present invention has excellent control effects on aphids, plant hoppers or whiteflies.

[0039] Furthermore, the pesticide composition or its formulation is applied to the pests to be controlled or the medium in which they grow.

[0040] In order to obtain the desired insecticidal effect, the dosage of the pesticide composition varies depending on various factors, such as the crop to be protected, the type of pest, the degree of infection, climatic conditions, application site, application method, dosage form used, etc.

[0041] The beneficial effects of the present invention are as follows:

[0042] 1) The present invention rationally combines compounds with different mechanisms of action, and at appropriate mass ratios, has a significant synergistic effect against Hemiptera pests;

[0043] 2) The insecticide composition of the present invention effectively improves the pest control effect, reduces the dosage of the pesticide, and alleviates environmental pressure. DETAILED DESCRIPTION

[0044] In order to make the technical solutions, objectives and advantages of the present invention more clearly understood, the present invention is described with reference to the following specific embodiments. However, the present invention can be implemented in various forms and should not be limited to the embodiments described herein.

[0045] Preparation Example

[0046] Preparation Example 1: 22% trifluanid·bifenthrin suspension (1:10)

[0047] Formula: 2% trifluanid, 20% bifenthrin, 1% sodium lauryl sulfate, 2% naphthalenesulfonate formaldehyde condensate, 4% polyoxyethylene sorbitan monooleate, 4% alkylphenol polyoxyethylene ether phosphate, 0.2% xanthan gum, 1% magnesium aluminum silicate, 5% ethylene glycol, 0.1% kason, 0.25% silicone oil, and deionized water to make up the balance;

[0048] Preparation method: According to the formula ratio, the active ingredients, surfactants and other functional additives are placed in a reactor in sequence, water is added and mixed evenly, and the suspension product is obtained by high-speed shearing, wet sand grinding, and finally homogenization filtration.

[0049] Preparation Example 2: 6% trifluanid·bifenthrin emulsion in water (1:5)

[0050] Formula: 1% triflumuron, 5% bifenthrin, 5% xylene, 15% cyclohexanone, 1% BHT, 1% arylphenol polyoxyethylene ether phosphate, 6% ethylene oxide-propylene oxide copolymer, 5% glycerol, 0.05% silicone defoamer, 0.1% xanthan gum, 0.1% benzoic acid, and deionized water to make up the balance;

[0051] Preparation method: According to the formula ratio, the active ingredient is dissolved in the solvent and an emulsifier is added to dissolve it into a uniform oil phase. Deionized water and antifreeze are mixed together to form a uniform water phase. Under high-speed shear, the oil phase is added to the water phase. Finally, a thickener, preservative and defoaming agent are added to form a well-dispersed water emulsion product.

[0052] Preparation Example 3: 12% trifluanid·bifenthrin emulsifiable concentrate (5:1)

[0053] Formula: 10% trifluanid, 2% bifenthrin, 15% DMF, 20% cyclohexanone, 14% styrylphenol polyoxyethylene ether, 2% calcium dodecylbenzenesulfonate, 20% propylene carbonate, and xylene makes up the balance;

[0054] Preparation method: according to the formula ratio, the active ingredient, solvent and cosolvent are added to the mixing kettle and stirred to dissolve, then the emulsifier is added and the balance is supplemented with the remaining solvent, and the mixture is stirred evenly in the stirring kettle. After filtering, the desired emulsifiable concentrate of the present invention is obtained.

[0055] Preparation Example 4: 24% trifluanid·bifenthrin dispersible oil suspension (1:2)

[0056] Formula: 8% trifluanid, 16% bifenthrin, 2% succinic acid sulfonate, 14% alkylaryl polyoxyethylene polyoxypropylene ether, 3% fatty alcohol polyoxyethylene ether, 2% calcium dodecylbenzene sulfonate, 1% silicon dioxide, 1% organic bentonite, 20% 200# solvent oil, and methyl oleate to make up the balance;

[0057] Preparation method: According to the formula ratio, the active ingredients, surfactants and other functional additives are placed in the reactor in sequence, oil is added and mixed evenly, and the dispersible oil suspension product is obtained by high-speed shearing, wet sand grinding, and finally homogenization filtration.

[0058] Preparation Example 5: 3% trifluanid·bifenthrin microemulsion (1:1)

[0059] Formula: 1.5% trifluanid, 1.5% bifenthrin, 10% glycerol fatty acid ester polyoxyethylene ether, 3% ethylene glycol oxyethylene polyoxypropylene ether, 2% polyoxyethylene sorbitan monooleate, 1% calcium dodecylbenzenesulfonate, 5% xylene, 18% cyclohexanone, 5% glycerol, 0.5% glycerol, 0.05% silicone defoamer, and deionized water to make up the balance;

[0060] Preparation method: According to the formula ratio of the embodiment, the active ingredient, solvent, emulsifier, etc. are mixed to prepare the oil phase, and the antifreeze agent and water are mixed to prepare the aqueous phase. The oil phase is added to the aqueous phase under stirring and stirred evenly. The shearing is continued for 10 minutes, and then the defoaming agent is added and stirred evenly to obtain small droplets of oil phase particles of 0.01 to 0.1 microns, that is, the microemulsion product is prepared.

[0061] Preparation Example 6: 20% trifluanid·bifenthrin water dispersible granules (3:1)

[0062] Formula: 15% trifluanid, 5% bifenthrin, 12% naphthalenesulfonate formaldehyde condensate, 5% lignin sulfonate, 3% sodium lauryl sulfate, 5% white carbon black, 25% starch, and kaolin to make up the balance;

[0063] Preparation method: According to the formula ratio, the active ingredient is added to the carrier, and surfactants and other functional additives are added thereto, mixed, and after air flow grinding, 10-25% water is added, and then kneading, granulation, drying, and screening are carried out to obtain a water-dispersible granule product; or the crushed powder is sprayed with water in a boiling granulator, granulated, dried, and then sieved to obtain the product.

[0064] Preparation Example 7: 33% trifluanid·bifenthrin wettable powder (10:1)

[0065] Formula: 30% trifluanid, 3% bifenthrin, 5% sodium lignin sulfonate, 5% naphthalene sulfonate formaldehyde condensate, 3% flaking powder BX, 5% white carbon black, and kaolin to make up the balance;

[0066] Preparation method: According to the formula ratio, the active ingredients, dispersants, wetting agents and fillers are mixed, uniformly stirred in a stirring kettle, and pulverized and mixed uniformly multiple times in a jet mill to prepare the wettable powder of the composition of the present invention.

[0067] Preparation Example 8: 16% trifluanid·isoxazole suspension (1:15)

[0068] Formula: 1% trifluanid, 15% isoxathiapiprolin, 1% triphenol polyoxyethylene ether, 4% arylphenol polyoxyethylene ether phosphate, 1% sodium lignin sulfonate, 0.25% xanthan gum, 1% magnesium aluminum silicate, 5% ethylene glycol, 0.01% isothiazolinone, 0.5% silicone oil, and deionized water to make up the balance;

[0069] Preparation method: Same as Preparation Example 1.

[0070] Preparation Example 9: 1.2% trifluanid·isoxazole emulsion in water (1:5)

[0071] Formula: 0.2% trifluanid, 1% isoxathiapiprolin, 2% BHT, 5% xylene, 30% cyclohexanone, 2% alkylphenol polyoxyethylene ether phosphate, 8% ethylene oxide-propylene oxide copolymer, 3% ethylene glycol, 4% glycerol, 0.05% silicone defoamer, 0.25% xanthan gum, 0.01% kason, and deionized water to make up the balance;

[0072] Preparation method: Same as Preparation Example 2.

[0073] Preparation Example 10: 11% trifluanid and isoxazole amide emulsifiable concentrate (10:1)

[0074] Formula: 10% trifluanid, 1% isoxathiapiprolin, 20% N-methylpyrrolidone, 15% fatty amine polyoxyethylene ether, 3% calcium dodecylbenzenesulfonate, 8% DMF, 20% cyclohexanone, and methyl oleate makes up the balance;

[0075] Preparation method: Same as Preparation Example 3.

[0076] Preparation Example 11: 26% trifluanid and isoxazole dispersible oil suspension (12:1)

[0077] Formula: 24% trifluanid, 2% isoxathiapiprolin, 15% castor oil polyoxyethylene ether, 2% alkylphenol polyoxyethylene ether, 1% calcium dodecylbenzenesulfonate, 2% sodium sulfosuccinate, 0.5% fumed silica, and soybean oil makes up the balance;

[0078] Preparation method: same as Preparation Example 4.

[0079] Preparation Example 12: 1.5% trifluanid·isoxazole microemulsion (2:1)

[0080] Formula: 1% trifluanid, 0.5% isoxazole amide, 10% styrylphenol polyoxyethylene ether, 5% anhydrous sorbitan polyoxyethylene ether, 2% styrylphenol polyoxyethylene ether phosphate, 1% calcium dodecylbenzenesulfonate, 2% xylene, 20% cyclohexanone, 5% ethylene glycol, 0.5% glycerol, 0.05% silicone defoamer, and deionized water to make up the balance;

[0081] Preparation method: Same as Preparation Example 5.

[0082] Preparation Example 13: 30% trifluanid and isoxazole water dispersible granules (5:1)

[0083] Formula: 25% trifluanid, 5% isoxazole amide, 8% sodium lignin sulfonate, 2% succinate ester sulfonate, 8% naphthalene sulfonate formaldehyde condensate, 5% white sugar, kaolin makes up the balance;

[0084] Preparation method: Same as Preparation Example 6.

[0085] Preparation Example 14: 28.5% trifluanid·isoxazole thiabendazim wettable powder (18:1)

[0086] Formula: 27% trifluanid, 1.5% isoxadiazole, 12% sodium lignin sulfonate, 2% succinate sulfonate, 2% sodium polycarboxylate, 6% bentonite, and kaolin makes up the balance;

[0087] Preparation method: Same as Preparation Example 7.

[0088] Indoor biological activity test

[0089] Example 1: Determination of toxicity to rice planthoppers

[0090] Test target: Brown planthopper (Nilaparvata lugens), 3rd instar nymph.

[0091] Test agents: triflumuron technical, cypermethrin technical, and isoxathiapiprolin technical.

[0092] Test Method: Healthy, uniformly growing rice seedlings approximately 10 cm in length were collected in groups of 15. These were washed and air-dried in a cool, dry place for later use. The test agent was dissolved in a suitable solvent to prepare a stock solution of a desired concentration. This stock solution was then diluted to five concentrations with a 0.1% Tween-80 solution. The rice seedlings were immersed in the solution for 30 seconds, then removed and air-dried. The base of the seedlings was wrapped with absorbent cotton, and the bottoms were immersed in water and placed in disposable plastic cups. Each cup was inoculated with approximately 40 uniformly sized, mid-instar nymphs and sealed with gauze. Each treatment was replicated four times, with a 0.1% Tween-80 solution serving as a blank control. After inoculation, the seedlings were incubated in an intelligent artificial climate chamber at a temperature of (28 ± 1)°C, a relative humidity of 75% ± 5%, and a photoperiod of 16 L:8 D. After 48 hours, the seedlings were inspected for mortality by gently touching the insects with a #0 brush; those that showed no movement were considered dead.

[0093] Calculation method:

[0094] Based on the survey data, calculate the mortality rate of each treatment. Calculate as follows:

[0095]

[0096] Where:

[0097] P——mortality rate, in percentage (%);

[0098] K——indicates the number of dead insects, the unit is head;

[0099] N——represents the total number of insects processed, in heads.

[0100]

[0101] Where:

[0102] P1——adjusted mortality rate, in percentage (%);

[0103] P t ——Treatment mortality rate, expressed in percentage (%);

[0104] P0 - blank control mortality rate, in percentage (%).

[0105] If the control mortality rate is less than 5%, no correction is required; if the control mortality rate is between 5% and 20%, correction should be made according to the correction mortality formula; if the control mortality rate is greater than 20%, the test needs to be repeated.

[0106] The DPS statistical analysis system was used to analyze the toxicity regression equation, correlation coefficient and LC 50 The activity of the test agent on the biological test material is evaluated by the value.

[0107] The co-toxicity coefficient (CTC value) of the mixture is calculated as follows:

[0108]

[0109] Where:

[0110] ATI - measured toxicity index of mixture;

[0111] S——LC of standard acaricide 50 , the unit is milligrams per liter (mg / L);

[0112] M——LC of the mixture 50 , the unit is milligrams per liter (mg / L).

[0113] TTI=TI A ×P A +TI B ×P B

[0114] Where:

[0115] TTI – Theoretical Toxicity Index of Mixtures;

[0116] TI A ——Agent toxicity index;

[0117] P A ——The percentage of agent A in the mixture, in percentage (%);

[0118] TI B ——Toxicity index of agent B;

[0119] P B ——The percentage of agent B in the mixture, in percentage (%).

[0120]

[0121] Where:

[0122] CTC – Co-toxicity coefficient;

[0123] ATI - measured toxicity index of mixture;

[0124] TTI - Theoretical Toxicity Index of Mixture.

[0125] A co-toxicity coefficient (CTC) of ≥120 indicates a synergistic effect; a CTC of ≤80 indicates an antagonistic effect; and a CTC of 80 < CTC <120 indicates an additive effect. The results of the laboratory test are shown in the table below:

[0126] Table 1 Results of indoor toxicity bioactivity test of trifluanid and isoxathiapiprolin against rice planthoppers

[0127]

[0128]

[0129] Indoor toxicity results showed that the combination of trifluanid and isoxafluanid exhibited good activity against rice planthoppers at appropriate mass ratios. At a mass ratio of 1:50 to 50:1, the co-toxicity coefficient against rice planthoppers was greater than 80, indicating an additive or synergistic effect. At a mass ratio of 1:30 to 20:1, the co-toxicity coefficient was greater than 120, indicating a synergistic effect. At a mass ratio of 1:20 to 10:1, the co-toxicity coefficient was greater than 130, indicating a significant synergistic effect.

[0130] Example 2: Alfalfa aphid toxicity assay

[0131] Test target: Alfalfa aphid (Aphis craccivora Koch).

[0132] Test agents: triflumuron technical, cypermethrin technical, and isoxathiapiprolin technical.

[0133] Test method: Dilute the test solution with water according to 5 concentration gradients, and use clean water as the control. Collect young alfalfa leaves with aphids from the alfalfa, and use a brush to select wingless adult aphids of basically the same size and body shape. 30 heads are used for each treatment, and each treatment is repeated 4 times. Immerse the leaves with aphids in the solution for 5 seconds, and soak the leaves with clean water for the blank control. After soaking the leaves, absorb the excess solution with filter paper and place them in a culture dish with moistened filter paper. Place them in a constant temperature box at (25±2)℃ for 24 hours and check the results. Criteria for judging the death of test insects: Use a brush to gently touch the insect body. If the insect body is completely motionless, it is considered dead, otherwise it is alive. Record the number of live and dead insects and calculate the mortality rate.

[0134] Calculation method of drug efficacy:

[0135] Based on the survey data, calculate the mortality rate of each treatment. Calculate as follows:

[0136]

[0137] Where:

[0138] P——mortality rate, in percentage (%);

[0139] K——indicates the number of dead insects, the unit is head;

[0140] N——represents the total number of insects processed, in heads.

[0141]

[0142] Where:

[0143] P1——adjusted mortality rate, in percentage (%);

[0144] P t ——Treatment mortality rate, expressed in percentage (%);

[0145] P0 - blank control mortality rate, in percentage (%).

[0146] If the control mortality rate is less than 5%, no correction is required; if the control mortality rate is between 5% and 20%, correction should be made according to the correction mortality formula; if the control mortality rate is greater than 20%, the test needs to be repeated.

[0147] The DPS statistical analysis system was used to analyze the toxicity regression equation, correlation coefficient and LC 50 The activity of the test agent on the biological test material is evaluated by the value.

[0148] The co-toxicity coefficient (CTC value) of the mixture is calculated as follows:

[0149]

[0150] Where:

[0151] ATI - measured toxicity index of mixture;

[0152] S——LC of standard acaricide 50 , the unit is milligrams per liter (mg / L);

[0153] M——LC of the mixture 50 , the unit is milligrams per liter (mg / L).

[0154] TTI=TI A ×P A +TI B ×P B

[0155] Where:

[0156] TTI – Theoretical Toxicity Index of Mixtures;

[0157] TI A ——Agent toxicity index;

[0158] P A ——The percentage of agent A in the mixture, in percentage (%);

[0159] TI B ——Toxicity index of agent B;

[0160] P B ——The percentage of agent B in the mixture, in percentage (%).

[0161]

[0162] Where:

[0163] CTC – Co-toxicity coefficient;

[0164] ATI - measured toxicity index of mixture;

[0165] TTI - Theoretical Toxicity Index of Mixture.

[0166] A co-toxicity coefficient (CTC) of 120 or higher indicates a synergistic effect; a co-toxicity coefficient (CTC) of 80 or lower indicates an antagonistic effect; and a co-toxicity coefficient (CTC) of 80 or lower indicates an additive effect.

[0167] The indoor test results are shown in the table below:

[0168] Table 2 Results of indoor bioactivity test on aphids using trifluanid and isoxathiapiprolin.

[0169]

[0170]

[0171] Indoor toxicity results showed that trifluanid and isoxafluanid compounded at appropriate mass ratios exhibited good activity against aphids. The co-toxicity coefficient against aphids was greater than 80 when the mass ratio of trifluanid to isoxafluanid was 1:50-50:1, indicating an additive or synergistic effect. The co-toxicity coefficient was greater than 120 when the mass ratio of trifluanid to isoxafluanid was 1:20-30:1, indicating a synergistic effect. The co-toxicity coefficient was greater than 130 when the mass ratio of trifluanid to isoxafluanid was 1:10-10:1, indicating a significant synergistic effect.

[0172] Table 3 Results of indoor bioactivity test of triflumuron and bifenthrin against aphids

[0173]

[0174] Indoor toxicity tests showed that triflubenzuron and bifenthrin, when combined at appropriate mass ratios, exhibited excellent control efficacy against aphids. At a mass ratio of 1:50 to 15:1, the co-toxicity coefficient was greater than 120, indicating a synergistic effect. At a mass ratio of 1:15 to 2:1, the co-toxicity coefficient was greater than 130, indicating a significant synergistic effect.

[0175] Field efficacy test:

[0176] Example 3: Field efficacy test on cotton aphid

[0177] Test basis: Refer to the national standard GB / T 17980.75-2004 "Guidelines for Field Efficacy Tests of Pesticides (II) Part 75: Insecticides for Control of Cotton Aphids".

[0178] Test location: This test was conducted in the cotton fields of Shahuliu Village, Qinhuangtai Township, Bincheng District, Binzhou City, Shandong Province. The soil fertility of the test site was medium.

[0179] Test target: cotton aphid (Aphis gossypii).

[0180] Experimental crops: cotton (Lumian 338).

[0181] Experimental design: experimental plot area 30m 2 Each treatment was repeated 4 times, and isolation zones were set between each experimental plot.

[0182] Test Method: The test was conducted once in May 2023. Spray application was carried out according to the experimental design. The target plants were sprayed with a backpack electric sprayer. Live insect counts were measured 1, 3, 7, and 14 days after application. The survey used a five-point diagonal sampling method, with four plants surveyed at each point. Live insect counts were determined on all leaves.

[0183] Calculation method of drug efficacy:

[0184]

[0185] Field efficacy test results:

[0186] Table 4 Field efficacy test on cotton aphid

[0187]

[0188] The results of field efficacy tests showed that the dosage of the active ingredient of 22% trifluanid·bifenthrin suspension concentrate (1:10) and 24% trifluanid·bifenthrin dispersible oil suspension concentrate (1:2) was 13 g / hm2. 2 , 1 day after application, the control effect on cotton aphids was higher than 86%, showing good rapid effect. 14 days after application, the control effect of the compound preparation was significantly better than that of the single-dose control, with a long-lasting effect.

[0189] Example 4: Field efficacy test on green peach aphid

[0190] Experimental Area: The experiment was conducted in an eggplant field in Xiaojia Village, Tanfang Town, Qingzhou City. Conventional production management was used, and the crop growth was generally consistent. The soil was loamy with an above-average organic matter content.

[0191] Test target: Green peach aphid (Myzus persicae).

[0192] Experimental crops: Eggplant.

[0193] Experimental design: The experiment set up 5 treatments, each treatment was repeated 4 times, the experimental plots were arranged in random blocks, and each treatment was repeated 4 times.

[0194] Test Method: Spray once in June 2023, during the peak aphid infestation period. Each agent was applied using a Shandong Weishi WS-16D manual sprayer. To prepare the agent, first add a small amount of water to the sprayer, then add the appropriate amount of the solution, shake thoroughly, and finally add enough water to meet the test requirements. Mix thoroughly before use.

[0195] Survey Method: Five random sampling points were selected from each experimental plot, with three plants designated at each point, for a total of 15 plants surveyed. Two leaves were collected from the top, middle, and bottom of the designated plants. The baseline insect population was determined before application. The number of surviving aphids in each treatment was then measured 3, 7, and 20 days after application. The corrected efficacy of each pesticide was then calculated.

[0196] Calculation method of drug efficacy:

[0197]

[0198] Field efficacy test results:

[0199] Table 5 Field efficacy test on green peach aphid

[0200]

[0201] The results of field efficacy tests showed that 11% trifluanid·isoxazole emulsifiable concentrate (10:1) and 1.2% trifluanid·isoxazole emulsifiable concentrate (1:5) had excellent control effects on peach aphids.

[0202] Example 5: Field efficacy test on rice planthoppers

[0203] The test site is a rice field in Baihu Town, Lujiang County, Hefei City, Anhui Province. The test site has a flat terrain, medium fertility, and convenient irrigation and drainage.

[0204] Test target: Rice.

[0205] Test subject: Rice planthopper.

[0206] Experimental design: The experiment set up 5 treatments, each treatment was repeated 4 times. Each experimental plot was randomly arranged in blocks, and each plot was 30m2 in size. 2 .

[0207] Test method: The test was conducted on August 7, 2023. A Gongnong-16 backpack sprayer was used to spray the entire rice plant.

[0208] Survey Method: Survey the base population before application and survey the number of rice planthoppers in each treatment 3, 7, and 15 days after application. Surveys were conducted using the parallel jump method at 10 locations per plot, with two rice clumps per location. The rice clumps were shaken or tapped, and the number of planthoppers floating on the water between the clumps was counted to calculate the reduction rate.

[0209] Calculation method of drug efficacy:

[0210]

[0211] Field efficacy test results:

[0212] Table 6 Results of field efficacy tests on rice planthoppers

[0213]

[0214] After the application of the pesticides, the entire process was recorded and compared. It was found that after 3d, 7d, and 15d of spraying of each compound preparation, the rice grew well, the spraying drug dosage was within the safe range, did not affect the growth of the plants, and had an ideal effect on the prevention and control of rice planthoppers, ensuring the healthy growth of rice.

[0215] In summary, through indoor toxicity tests and field efficacy tests, it can be seen that the pesticide composition of the present invention has a good control effect on Hemiptera pests, is safe for target crops, has significant control effects, and is superior to a single agent in delaying the development of resistance and prolonging the effectiveness.

[0216] Although the present application describes specific embodiments in detail by way of example, the disclosure of the present application may adopt various modifications and alternative forms. However, it should be understood that the disclosure of the present application is not limited to the specific forms disclosed. On the contrary, the disclosure of the present application covers all modifications, equivalents and alternative forms within the scope of the disclosure of the present application, and the scope of the present application is limited by the appended claims and their legal equivalents.

Claims

1. An insecticidal composition containing trifluralin, characterized in that: The active ingredients in the insecticidal composition include active ingredient A and active ingredient B, the active ingredient A is trifluanid, the active ingredient B is isoxathiapiprolin, and the mass ratio of the active ingredient A to the active ingredient B is 1:30 to 30:

1.

2. The insecticidal composition according to claim 1, wherein the mass ratio of the active ingredient A to the active ingredient B is 1:20 to 20:

1.

3. The insecticidal composition according to claim 1, characterized in that The total weight of the insecticide composition is 100 wt %, and the total weight of the active ingredient A and the active ingredient B accounts for 0.2% to 75% of the total weight of the insecticide composition.

4. The insecticidal composition according to claim 1, characterized in that The insecticide composition contains auxiliary ingredients in addition to the active ingredients, and the auxiliary ingredients are selected from one or more of wetting agents, dispersants, emulsifiers, thickeners, disintegrants, antifreeze agents, defoaming agents, preservatives, stabilizers, synergists or carriers.

5. The insecticidal composition according to claim 1, characterized in that The formulation of the insecticide composition is a solid preparation or a liquid preparation.

6. The insecticidal composition according to claim 5, characterized in that The preparation dosage forms are suspension, emulsifiable concentrate, microemulsion, aqueous emulsion, dispersible oil suspension, wettable powder and water dispersible granules.

7. Use of the insecticidal composition according to any one of claims 1 to 6 for controlling agricultural pests, characterized in that: The pests are Hemiptera pests, and the Hemiptera pests are aphids or plant hoppers.

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