A sanitary insecticide composition and its application

Abstract

The invention discloses a sanitary insecticide composition and application thereof. The active ingredients are compounded by component A and component B. By weight, the total weight of component A and component B accounts for 2% to 60% of the total weight of the insecticide composition, and the balance is auxiliary materials. Component A is a piperic acid derivative compound; component B is any one of imidacloprid, acetamiprid, thiacloprid, thiamethoxam, dinotefuran, flupyradone, and sulfoxaflor. The compounded insecticide composition of the invention has a synergistic effect at a certain ratio, and has improved knockdown and lethal effects on flies compared with a single agent.

Description

Technical Field

[0001] The present invention relates to a sanitary insecticide composition and application thereof. The active ingredients of the sanitary insecticide composition are component A and component B. Component A is a piperic acid derivative compound, and component B is any one of imidacloprid, acetamiprid, thiacloprid, thiamethoxam, dinotefuran, flupyradone, and sulfoxaflor. Background Art

[0002] Due to long-term use of pesticides, pests are becoming increasingly resistant to organophosphates, carbamates, and pyrethroids, and resistance is becoming a serious problem. In practical applications, highly active compounds are needed to improve control efficacy and reduce pesticide usage.

[0003] Chinese invention patent CN112457288 discloses a piperic acid derivative and its applications, including compound I-72, which exhibits contact and stomach toxicity, as well as good conductivity. Furthermore, compound I-72 has not been found to be useful for residual spraying of sanitary pests. The compound exhibits high activity and low resistance. The present invention, through experimental screening, has identified a synergistic nicotinic insecticide with the compound. The compound, with its two different mechanisms of action, exhibits significantly improved efficacy compared to a single dose of Formula I, and significantly higher efficacy than commercially available products.

[0004] The structural formula of the compound is as follows:

[0005]

[0006] Residual spraying is a common method of applying pesticides in the field of pest control. Traditional residual spraying requires large amounts of spraying to increase the contact area with flies, passively killing pests. The present invention reduces the application rate by adding an attractant composition, improving the efficacy of the drug through active attraction and reducing the frequency of application. Summary of the Invention

[0007] The technical problem to be solved by the present invention is to address the deficiencies in the prior art and provide a sanitary insecticide composition and its application. A piperic acid derivative compound (Compound I-72) is used as one of the active ingredients and is compounded with a nicotine insecticide with strong lethality. The composition can significantly improve the knockdown rate and mortality rate, quickly reduce fly density, delay the development of resistance, and reduce the frequency of application.

[0008] In order to achieve the above object, the present invention adopts the following technical solutions:

[0009] The present invention first provides a sanitary insecticide composition and its application.

[0010] The present invention provides a sanitary insecticide composition, wherein the active ingredients are compounded from component A and component B, wherein the total weight of component A and component B accounts for 2% to 60% of the total weight of the insecticide composition, and the remainder is auxiliary materials; the component A is a piperic acid derivative compound represented by formula I (referred to as compound I-72);

[0011]

[0012] The component B is any one of imidacloprid, acetamiprid, thiacloprid, thiamethoxam, dinotefuran, flupyradone and sulfoxaflor.

[0013] In the above technical solution, the weight ratio of component A to component B is 10:1 to 1:20, preferably 2:1 to 1:20.

[0014] In the above technical solution, the auxiliary materials include adjuvants and attractant compositions, wherein the adjuvants are a mixture of any three or more of a dispersant, a wetting agent, a disintegrant, a filler, an antifreeze agent, a thickener, a preservative, a defoaming agent and deionized water in any proportion.

[0015] In the above technical solution, the insecticide composition is in the form of a wettable powder, a suspension concentrate, a water-dispersible granule or a dry suspension concentrate.

[0016] In the above technical solution, the insecticide composition, when in the form of a wettable powder, comprises the following raw materials in weight percentage: 1-20% component A, 1-40% component B, 2-6% wetting agent, 7-18% dispersant, 2-5% attractant composition, and the filler is supplemented to 100%.

[0017] In the above technical solution, the insecticide composition, when in the form of a suspension, comprises the following raw materials in weight percentage: 1-20% of component A, 1-20% of component B, 1-8% of a wetting agent, 1-8% of a dispersant, 3-7% of an antifreeze agent, 0.3-2% of a preservative, 0.1-1% of a defoaming agent, 0.5-3% of a thickener, 2-5% of an attractant composition, and deionized water is added to 100%.

[0018] In the above technical solution, the insecticide composition, when in the form of water-dispersible granules, comprises the following raw materials in weight percentage: 1-20% component A, 1-40% component B, 2-12% wetting agent, 5-15% dispersant, 2-5% disintegrant, 2-5% attractant composition, and the filler is supplemented to 100%.

[0019] In the above technical solution, the insecticide composition, when in the form of a dry suspension, comprises the following raw materials in weight percentage: 1-20% component A, 1-40% component B, 1-8% wetting agent, 1-8% dispersant, 2-5% attractant composition, and the filler is supplemented to 100%.

[0020] In the above technical solution, the attractant composition includes the following raw materials in weight percentage: 5% agar, 5% sorbitol, 60% attractant, 8% β-cyclodextrin, 0.5% xanthan gum, 0.3% to 1.5% titanium dioxide and the balance deionized water; the attractant is any one or more of indole, furanone, lactic acid, n-heptanoic acid, methyl acrylate, trimethyl indole, and dimethyl disulfide.

[0021] In the above technical solution, the attractant composition is prepared by the following method: agar, sorbitol, attractant, β-cyclodextrin, xanthan gum, and water are weighed in proportion, heated to a puffed state, 0.3% to 1.0% titanium dioxide is added, and stirred evenly to obtain a wet gel-like attractant composition; the same steps are followed, but when the amount of titanium dioxide added is 1.0% to 1.5%, the attractant composition is naturally dried or oven-dried and then crushed to obtain a dry gel-like attractant composition.

[0022] In the above technical solution, the wet gel-like attractant composition gel can be directly added to the suspension; the dry gel-like attractant composition can be used in wettable powders, water-dispersible granules, and dry suspensions after being pulverized by air flow.

[0023] In the above technical solution, the dispersant is selected from any one of polycarboxylates, lignin sulfonates, alkylphenol polyoxyethylene ether formaldehyde condensates, naphthalenesulfonic acid formaldehyde condensates sodium salt, nonionic hydroxy polyethylene oxide block copolymers, fatty amine polyoxyethylene ethers, fatty acid polyoxyethylene esters, and glycerol fatty acid ester polyoxyethylene ethers, or a mixture of two or more in any proportion.

[0024] In the above technical solution, the wetting agent is selected from: any one of naphthalenesulfonate, sodium lauryl sulfate, pull-opening powder BX, alkylphenol polyoxyethylene ether formaldehyde condensate sulfate, alkylbenzene polyoxyethylene ether phosphate, phenylethylphenol polyoxyethylene ether phosphate, alkyl sulfate, alkyl sulfonate, dodecylbenzenesulfonic acid, or a mixture of two or more in any proportion.

[0025] In the above technical solution, the disintegrant is selected from: any one of sodium chloride, ammonium sulfate, sodium carbonate, sodium bicarbonate, and sodium sulfate, or a mixture of two or more of the above in any proportion.

[0026] In the above technical solution, the filler is selected from: any one of kaolin, white carbon black, corn starch, attapulgite, calcium carbonate, light calcium, diatomaceous earth, or a mixture of two or more of them in any proportion.

[0027] In the above technical solution, the antifreeze agent is any one of ethylene glycol, propylene glycol, glycerol, glycerin, and urea, or a mixture of two or more of them in any proportion.

[0028] In the above technical solution, the thickener is any one of xanthan gum, hydroxyethyl cellulose, methyl cellulose, magnesium aluminum silicate, and organic bentonite, or a mixture of two or more of the above in any proportion.

[0029] In the above technical solution, the preservative is any one of sodium benzoate, benzoic acid, potassium sorbate, and kasone, or a mixture of two or more of the above in any proportion.

[0030] In the above technical solution, the defoaming agent is any one of polydimethylsiloxane, silicone oil, glycerol ricinoleate, and distearylethylenediamine, or a mixture of two or more in any proportion.

[0031] The present invention also provides an application of the sanitary insecticide composition for preventing and controlling sanitary pests in places where sanitary pests are present.

[0032] In the above technical solution, the sanitary pests are flies.

[0033] In the above technical solution, the flies include flies of the Muscidae family and the Calliphoridae family, specifically house flies, city flies, summer toilet flies, toilet flies, stable flies, big-headed golden flies, silk-colored green flies, copper green flies, bright green flies, red-headed blowflies, giant-tailed Ali flies, bedflies, and new land bedflies.

[0034] In the above technical solution, when the sanitary insecticide composition is used to control sanitary pests, the sanitary insecticide composition is diluted 50-1000 times with water and sprayed on the surfaces of objects such as walls, doors and windows, ceilings, plants and household items in places where sanitary pests are infested, so that the insecticide composition remains on the surfaces of the above objects, thereby knocking down and killing the sanitary pests. Its applicable dosage forms are suspension concentrate, wettable powder, water-dispersible granules and dry suspension concentrate.

[0035] Compared with the existing technology, it has the following characteristics:

[0036] The insecticide composition of the present invention has a synergistic effect at a certain ratio. The combination of two insecticides with different action mechanisms has higher activity than a single agent, can significantly increase the knockdown rate and mortality rate, quickly reduce fly density, and delay the development of resistance. At the same time, the addition of the attractant composition improves the application effect and reduces the application frequency. DETAILED DESCRIPTION

[0037] The following describes in detail the specific implementation of the technical solution of the present invention, but the present invention is not limited to the following description:

[0038] The attractant composition in the embodiment of the present invention is prepared by the following method:

[0039] Agar, sorbitol, attractant, β-cyclodextrin, xanthan gum and water are weighed in proportion, heated to a puffed state, 0.5% titanium dioxide is added and stirred evenly to obtain a wet gel-like attractant composition; the same steps are used as above, but when the amount of titanium dioxide added is 1.5%, the mixture is naturally dried or oven-dried and then crushed to obtain a dry gel-like attractant composition.

[0040] The preparation methods of the various dosage forms in the embodiments of the present invention are as follows:

[0041] The laboratory preparation method of wettable powder is: add component A, component B, wetting agent, dispersant, dry gel attractant composition and filler into a food processor and mix them evenly, then put them into a jet mill to grind them.

[0042] The laboratory preparation method of the suspension concentrate is as follows: weigh the wetting agent, dispersant, antifreeze, preservative, defoaming agent, wet gel-like attractant composition and deionized water according to the ratio, add them into a beaker and mix evenly, then add component A and component B into the beaker, and then transfer to a sand mill, add zirconium oxide beads into the sand mill, grind for 2-3 hours, add thickener and continue grinding for 0.5 hours to control the particle size D95 to below 5 microns, filter to remove the zirconium oxide beads, and the suspension concentrate can be prepared.

[0043] The laboratory preparation method of water-dispersible granules is as follows: add component A, component B, wetting agent, dispersant, disintegrant, dry gel-like attractant composition and filler into a food processor and mix them evenly, then put them into a jet mill for grinding, mix them again with a food processor, add an appropriate amount of water, extrude granules with a granulator and dry them.

[0044] The laboratory preparation method of the dry suspension concentrate is: weigh the wetting agent, dispersant, dry gel-like attractant composition, filler and water according to the ratio, add them into a beaker and mix evenly, then add component A and component B into the beaker, and then transfer it to a sand mill, add zirconium oxide beads into the sand mill, grind for 2-3 hours to control the particle size D95 to below 5 microns, filter to remove the zirconium oxide beads, and dry the obtained material in a spray dryer to obtain the product.

[0045] The present invention will be described below in conjunction with specific embodiments:

[0046] Formulation Example 1: 2% Compound I-72·sulfoxaflor suspension concentrate

[0047] Compound I-721g, sulfoxaflor 1g, sodium lauryl sulfate 4g, sodium lignin sulfonate 6g, attractant composition 5g (attractant: methyl acrylate), propylene glycol 2g, ethylene glycol 3g, potassium sorbate 0.5g, magnesium aluminum silicate 1g, xanthan gum 0.3g, silicone oil 0.2g, and deionized water to 100g. A suspension concentrate was prepared as described above.

[0048] Formulation Example 2: 20% Compound I-72·sulfoxaflor suspension concentrate

[0049] Compound I-725g, sulfoxaflor 15g, sodium lauryl sulfate 4g, sodium lignin sulfonate 6g, attractant composition 5g (attractant: trimethyl indole), propylene glycol 2g, ethylene glycol 3g, potassium sorbate 0.5g, magnesium aluminum silicate 1g, xanthan gum 0.3g, polydimethylsiloxane 0.2g, and deionized water to 100g. A suspension concentrate was prepared as described above.

[0050] Formulation Example 3: 20% Compound I-72·sulfoxaflor suspension concentrate

[0051] Compound I-7215g, sulfoxaflor 5g, sodium lauryl sulfate 4g, potassium lignin sulfonate 6g, propylene glycol 4g, attractant composition 5g (attractant: furanone), potassium sorbate 0.5g, magnesium aluminum silicate 1g, xanthan gum 0.3g, glyceryl ricinoleate 0.2g, and deionized water to 100g. A suspension concentrate was prepared as described above.

[0052] Preparation Example 4: 15% Compound I-72·Flupyrrolidone Suspension

[0053] Compound I-725g, imidacloprid 10g, alkyl sulfate sodium salt 6g, alkyl sulfonic acid sodium salt 2g, polycarboxylate potassium salt 3g, lignin sulfonic acid sodium salt 4g, attractant composition 3g (attractant: furanone), propylene glycol 1g, urea 3g, potassium sorbate 0.5g, magnesium aluminum silicate 0.5g, xanthan gum 0.4g, distearyl ethylenediamine 0.2g, and deionized water to 100g. A suspension concentrate was prepared as described above.

[0054] Formulation Example 5: 20% Compound I-72·Imidacloprid Suspension

[0055] Compound I-722g, imidacloprid 18g, alkylbenzene polyoxyethylene ether phosphate 2g, alkyl sulfonic acid sodium salt 2g, lignin sulfonic acid sodium salt 4g, attractant composition 4g (attractant: lactic acid), glycerin 5g, sodium benzoate 0.5g, kasone 0.3g, magnesium aluminum silicate 0.5g, xanthan gum 0.2g, silicone oil 0.2g, and deionized water to 100g. A suspension concentrate was prepared as described above.

[0056] Formulation Example 6: 60% Compound I-72·Dinotefuran Water Dispersible Granules

[0057] Water-dispersible granules were prepared by the following method: 20 g of compound I-72, 40 g of dinotefuran, 2 g of potassium alkyl sulfate, 5 g of sodium ligninsulfonate, 5 g of sodium naphthalenesulfonic acid formaldehyde condensate, 1 g of sodium sulfate, 3 g of ammonium sulfate, 2 g of attractant composition (attractant: dimethyl disulfide), and corn starch to make up to 100 g.

[0058] Formulation Example 7: 42% Compound I-72·Dinotefuran Water Dispersible Granules

[0059] Water-dispersible granules were prepared by the following method: 22g of compound I-7, 40g of dinotefuran, 8g of lakai powder BX, 3g of sodium lauryl sulfate, 10g of naphthalenesulfonic acid formaldehyde condensate sodium salt, 5g of ammonium sulfate, 5g of attractant composition (attractant: dimethyl disulfide), and kaolin to make up to 100g.

[0060] Formulation Example 8: 40% Compound I-72·Thiamethoxam Water Dispersible Granules

[0061] Water-dispersible granules were prepared by the above method: 25 g of compound I-7, 35 g of thiamethoxam, 6 g of sodium lauryl sulfate, 8 g of sodium ligninsulfonate, 6 g of sodium naphthalenesulfonic acid formaldehyde condensate, 3 g of sodium sulfate, 5 g of attractant composition (attractant: n-heptanoic acid), and corn starch to make up to 100 g.

[0062] Formulation Example 9: 50% Compound I-72·Acetamiprid Wettable Powder

[0063] A wettable powder was prepared by the following method: 10 g of compound I-72, 40 g of acetamiprid, 4 g of alkylbenzene polyoxyethylene ether phosphate, 6 g of naphthalenesulfonic acid formaldehyde condensate sodium salt, 4 g of ligninsulfonic acid sodium salt, 3 g of white carbon black, 5 g of attractant composition (attractant: n-heptanoic acid), and kaolin to make up to 100 g.

[0064] Formulation Example 10: 30% Compound I-72·Acetamiprid Wettable Powder

[0065] A wettable powder was prepared by the following method: 10 g of compound I-72, 20 g of acetamiprid, 5 g of sodium sulfate of alkylphenol polyoxyethylene ether formaldehyde condensate, 10 g of sodium naphthalenesulfonic acid formaldehyde condensate, 2 g of fatty amine polyoxyethylene ether, 3 g of white carbon black, 5 g of attractant composition (attractant: methyl acrylate), and kaolin to 100 g.

[0066] Formulation Example 11: 42% Compound I-72·Imidacloprid Wettable Powder

[0067] A wettable powder was prepared by the following method: 22g of compound I-7, 40g of acetamiprid, 4g of sodium lauryl sulfate, 12g of naphthalenesulfonic acid formaldehyde condensate sodium salt, 3g of white carbon black, 15g of corn starch, 5g of an attractant composition (attractant: trimethyl indole), and diatomaceous earth to make up to 100g.

[0068] Formulation Example 12: 60% Compound I-72·Imidacloprid Dry Suspension

[0069] A dry suspension concentrate was prepared by the following method: 20 g of compound I-72, 40 g of imidacloprid, 5 g of sodium dodecylbenzenesulfonate, 5 g of potassium polycarboxylate, 3 g of sodium naphthalenesulfonic acid formaldehyde condensate, 5 g of attractant composition (attractant: methyl acrylate), and corn starch to make up to 100 g.

[0070] Formulation Example 13: 42% Compound I-72·sulfoxaflor dry suspension

[0071] A dry suspension concentrate was prepared by the above method: 22g of compound I-7, 40g of sulfoxaflor, 4g of sodium lauryl sulfate, 4g of naphthalenesulfonic acid sodium salt, 3g of naphthalenesulfonic acid formaldehyde condensate sodium salt, 5g of attractant composition (attractant: furanone), 10g of white carbon black, and corn starch to make up to 100g.

[0072] Comparative Example 1: 20% Compound I-72 Wettable Powder

[0073] A wettable powder was prepared by the following method: 20 g of compound I-72, 5 g of potassium alkyl sulfate, 10 g of sodium naphthalenesulfonic acid formaldehyde condensate, 2 g of fatty amine polyoxyethylene ether, 3 g of white carbon black, 5 g of attractant composition (attractant: methyl acrylate), and kaolin to make up to 100 g.

[0074] Comparative Example 2: 20% dinotefuran wettable powder

[0075] A wettable powder was prepared by the following method: 20 g of dinotefuran, 5 g of potassium salt of alkyl sulfate, 10 g of sodium salt of naphthalenesulfonic acid formaldehyde condensate, 2 g of fatty amine polyoxyethylene ether, 3 g of white carbon black, 5 g of attractant composition (attractant: methyl acrylate), and kaolin to make up to 100 g.

[0076] Comparative Example 3: 20% Compound I-72·sulfoxaflor suspension concentrate

[0077] Compound I-725g, sulfoxaflor 15g, sodium lauryl sulfate 4g, lignin sulfonate 6g, propylene glycol 2g, ethylene glycol 3g, potassium sorbate 0.5g, magnesium aluminum silicate 1g, xanthan gum 0.3g, silicone oil 0.2g, and deionized water to 100g. A suspension concentrate was prepared as described above.

[0078] Comparative Example 4: 42% Compound I-72·Dinotefuran Water Dispersible Granules

[0079] Water-dispersible granules were prepared by the above method: 22g of compound I-7, 40g of dinotefuran, 8g of lakai powder BX, 3g of sodium lauryl sulfate, 10g of naphthalenesulfonic acid formaldehyde condensate sodium salt, 5g of ammonium sulfate, and kaolin to make up to 100g.

[0080] Comparative Example 5: 30% Compound I-72·Acetamiprid Wettable Powder

[0081] Compound I-72 10g, acetamiprid 20g, alkyl sulfate potassium salt 5g, naphthalenesulfonic acid formaldehyde condensate sodium salt 10g, fatty amine polyoxyethylene ether 2g, white carbon black 3g, kaolin to 100g. Prepare a wettable powder according to the above method.

[0082] Control agent 1: 10% highly effective chlorfenapyr wettable powder (commercially available)

[0083] Verification test 1: co-toxicity coefficient test

[0084] (1) Test subjects: Houseflies (laboratory-reared)

[0085] (2) Test method: Refer to GB / T26350-2010 "Test methods for insecticide resistance in flies - Housefly bioassay" and NY / T1154.7-2006 "Guidelines for indoor bioassay of pesticides - Insecticides - Part 7: Determination of the combined effect of mixtures"

[0086] (3) Data statistics: The test agent was first dissolved in dichloromethane, and then serially diluted with an aqueous solution containing 0.1% Triton-X100 at a ratio of 1:9. 1 mL of each diluted solution was added to a 150 mL serum bottle. The serum bottle was rotated continuously to evenly distribute the solution on the inner wall of the bottle. The bottle was placed in a fume hood overnight to allow the organic solvent to evaporate completely. Test insects were placed in the concentration range that resulted in 100% mortality and 100% survival. Within this range, the appropriate concentration was selected and serially diluted with an aqueous solution containing 0.1% Triton-X100. 1 mL of each diluted solution was added to a 150 mL serum bottle. The serum bottle was rotated continuously to evenly distribute the solution on the inner wall of the bottle. The bottle was placed in a fume hood overnight to allow the organic solvent to evaporate completely. Vaseline was then applied to the neck of the serum bottle. 20 test insects were placed in each bottle. The experiment was repeated 5 times. The corresponding solvent treatment was used as the control group. After 1 hour, all test insects were transferred to clean containers for standard feeding. After 24 hours, the number of deaths was examined and counted. The LC50 and 95% confidence limits of each agent were calculated using SPSS statistical analysis software. The results are shown in the following table:

[0087] Table 1 Co-toxicity coefficient of component A and thiacloprid to housefly

[0088]

[0089] As can be seen from Table 1, when the combination ratio of compound I-72: thiacloprid is between 10:1 and 1:20, the co-toxicity coefficient to houseflies is greater than 120, showing a synergistic effect. In particular, when the combination ratio is between 2:1 and 1:20, the co-toxicity coefficient to houseflies is greater than 150, showing a significant synergistic effect.

[0090] Table 2 Co-toxicity coefficient of component A and flupyrazone to housefly

[0091]

[0092] As can be seen from Table 2, when the compound I-72: flupyradifurone ratio is between 10:1 and 1:20, the co-toxicity coefficient to housefly is greater than 120, showing a synergistic effect. In particular, when the compound ratio is between 2:1 and 1:20, the co-toxicity coefficient to housefly is greater than 150, showing a significant synergistic effect.

[0093] In addition, when the compound I-72 and other components B are mixed at a ratio of 2:1 to 1:20, there is also a similar synergistic effect on flies.

[0094] Verification test 2: Fly retention efficacy test

[0095] (1) Test subjects: Housefly

[0096] (2) Test method: Refer to GB / T13917.1-2009 Indoor efficacy test and evaluation of public health insecticides for pesticide registration, residual spray test.

[0097] (3) Test agents: Preparation Examples 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, and 13 were diluted with water to 400 ppm, and Comparative Example 1, Comparative Example 2, and Control Agent 1 were diluted with water to 400 ppm.

[0098] (4) Statistics:

[0099] Table 4 Results of efficacy tests on houseflies using several treatments

[0100] Treatment group target KT50 24 mortality rate Preparation Example 1 Housefly 5′02″ 91.7％ Preparation Example 2 Housefly 3′45″ 100％ Preparation Example 3 Housefly 3′56″ 93.3％ Preparation Example 4 Housefly 4′25″ 95％ Preparation Example 5 Housefly 4′23″ 95％ Preparation Example 6 Housefly 4′08″ 100％ Preparation Example 7 Housefly 4′11″ 96.7％ Preparation Example 8 Housefly 4′31″ 95％ Preparation Example 9 Housefly 4′27″ 95％ Preparation Example 10 Housefly 3′41″ 96.7％ Formulation Example 11 Housefly 3′36″ 96.7％ Formulation Example 12 Housefly 3′36″ 96.7％ Formulation Example 13 Housefly 4′26″ 95％ Comparative Example 1 Housefly 5′26″ 85％ Comparative Example 2 Housefly 6′46″ 75％ Control drug 1 Housefly 8′42″ 70.0％

[0101] Verification test 3: Effect of attractant composition on drug efficacy

[0102] (1) Test subjects: Housefly

[0103] (2) Test method: Refer to GB / T13917.1-2009 Indoor efficacy test and evaluation of public health insecticides for pesticide registration, residual spray test.

[0104] (3) Test agent:

[0105] Formulation Examples 2, 7, and 10 were diluted with water to 400 ppm, and Comparative Examples 3, 4, and 5 were diluted with water to 400 ppm.

[0106] (4) Statistics:

[0107] Table 4 Results of efficacy tests on houseflies using several treatments

[0108] Treatment group target KT50 24-hour mortality rate Preparation Example 2 Housefly 3′41″ 100％ Comparative Example 3 Housefly 4′56″ 86.7％ Preparation Example 7 Housefly 4′22″ 96.7％ Comparative Example 4 Housefly 5′16″ 81.7％ Preparation Example 10 Housefly 3′47″ 96.7％ Comparative Example 5 Housefly 4′52″ 85％

[0109] The test results show that the knockdown time and mortality rate of the agent with the attractant composition added are better than those without the attractant composition.

[0110] The above examples are only for illustrating the technical concept and technical features of the present invention and are not intended to limit the scope of protection of the present invention. Any equivalent transformation or modification made based on the essence of the present invention should be included in the scope of protection of the present invention.

Claims

1. A sanitary insecticide composition, characterized in that The active ingredient is compounded from component A and component B. The total weight of component A and component B accounts for 2% to 60% of the total weight of the insecticide composition, and the remainder is auxiliary materials, which include an attractant composition. The component A is a piperic acid derivative compound shown in formula I The component B is any one of imidacloprid, acetamiprid, thiacloprid, thiamethoxam, dinotefuran, flupyradone, and sulfoxaflor; the weight ratio of the component A to the component B is 10:1 to 1:20; The attractant composition comprises the following raw materials in percentage by weight: 5% agar, 5% sorbitol, 60% attractant, 8% beta-cyclodextrin, 0.5% xanthan gum, 0.3% to 1.5% titanium dioxide and the balance deionized water; the attractant is any one or more of indole, furanone, lactic acid, n-heptanoic acid, methyl acrylate, trimethyl indole and dimethyl disulfide.

2. The sanitary insecticide composition according to claim 1, characterized in that The auxiliary materials include adjuvants and attractant compositions, wherein the adjuvants are a mixture of any three or more of a dispersant, a wetting agent, a disintegrant, a filler, an antifreeze agent, a thickener, a preservative, a defoaming agent and deionized water in any proportion; the insecticide composition is in the form of a wettable powder, a suspension, a water-dispersible granule or a dry suspension.

3. The sanitary insecticide composition according to claim 2, characterized in that The insecticide composition, when in the form of a wettable powder, comprises the following raw materials in weight percentage: 1-20% of component A, 1-40% of component B, 2-6% of a wetting agent, 7-18% of a dispersant, 2-5% of an attractant composition, and the filler is supplemented to 100%.

4. The sanitary insecticide composition according to claim 2, characterized in that The insecticide composition, when in the form of a suspension, comprises the following raw materials in weight percentage: 1-20% of component A, 1-20% of component B, 1-8% of a wetting agent, 1-8% of a dispersant, 3-7% of an antifreeze agent, 0.3-2% of a preservative, 0.1-1% of a defoaming agent, 0.5-3% of a thickener, 2-5% of an attractant composition, and deionized water is added to make up the total weight to 100%.

5. The sanitary insecticide composition according to claim 2, characterized in that The insecticide composition, when in the form of water-dispersible granules, comprises the following raw materials in weight percentage: 1-20% of component A, 1-40% of component B, 2-12% of a wetting agent, 5-15% of a dispersant, 2-5% of a disintegrant, 2-5% of an attractant composition, and the filler makes up to 100%.

6. The sanitary insecticide composition according to claim 2, characterized in that The insecticide composition, when in the form of a dry suspension, comprises the following raw materials in weight percentage: 1-20% of component A, 1-40% of component B, 1-8% of a wetting agent, 1-8% of a dispersant, 2-5% of an attractant composition, and the filler makes up to 100%.

7. The sanitary insecticide composition according to claim 1, characterized in that The attractant composition is prepared by the following method: agar, sorbitol, attractant, β-cyclodextrin, xanthan gum and water are weighed in proportion, heated to a puffed state, 0.3% to 1.0% titanium dioxide is added, and stirred evenly to obtain a wet gel-like attractant composition; the same steps are followed, but when the amount of titanium dioxide added is 1.0% to 1.5%, the attractant composition is naturally dried or oven-dried and then crushed to obtain a dry gel-like attractant composition; the wet gel-like attractant composition gel can be directly added to a suspension agent; the dry gel-like attractant composition is crushed by air flow and used in wettable powders, water-dispersible granules and dry suspension agents.

8. Use of the sanitary insecticide composition according to claim 1 for controlling sanitary pests in places where sanitary pests are present, characterized in that: The sanitary pests specifically include house flies, city flies, summer toilet flies, toilet flies, stable flies, big-headed golden flies, silk-tailed green flies, copper green flies, bright green flies, red-headed blowflies, giant-tailed blowflies, leech flies, and new land blowflies.

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