Nutritional composition rich in roxburgh rose SOD (superoxide dismutase) and various peptides and formula proportion of nutritional composition

Abstract

The invention discloses a nutritional composition rich in roxburgh rose SOD (superoxide dismutase) and various peptides and a formula proportion of the nutritional composition, and relates to the field of nutritional supplement and health care. The fifteen plant peptides are black sesame peptide, black bean peptide, quinoa peptide, oat peptide, millet peptide, corn peptide, Chinese yam peptide, puerarin peptide, Chinese chestnut peptide, walnut peptide, sea-buckthorn peptide, grape seed peptide, medlar peptide, spina date seed peptide and selenium-enriched malt peptide; according to the nutritional composition rich in the roxburgh rose SOD and the various peptides and the formula proportion of the nutritional composition, the roxburgh rose SOD and the fifteen plant peptides are combined together, the synergistic effect of various nutritional ingredients is exerted, and comprehensive nutritional supplement and health care effects are provided; all the components are derived from natural food materials, so that the product is safe and reliable and has no side effect; sOD and plant peptide substances have the characteristics of small molecular weight and easiness in absorption, can be quickly absorbed and utilized by a human body, improve the bioavailability of nutritional ingredients, and are suitable for adults of all ages.

Description

Technical Field

[0001] The invention relates to a nutritional supplement health care technology, and in particular to a nutritional composition rich in roxburghii superoxide dismutase (SOD) and multiple peptides and a formula ratio thereof. Background Art

[0002] With the rapid development of modern social economy and the significant improvement of people's quality of life, people are paying more and more attention to health issues, especially the demand for foods and medicines with health care functions is showing a rapid growth trend. This change has prompted the health industry to continue to innovate and strive to develop more efficient, safe and multifunctional health products to meet market demand. In the field of health care, antioxidants have attracted much attention because they can effectively fight free radicals in the body, delay cell aging, and prevent a variety of chronic diseases. Among them, superoxide dismutase (SOD), as a key endogenous antioxidant enzyme, has become a hot topic in antioxidant research due to its powerful free radical scavenging ability. SOD can catalyze the dismutation reaction of superoxide anion radicals to generate hydrogen peroxide and oxygen, thereby effectively protecting cells from damage caused by oxidative stress, which is of great significance for maintaining the health of the body.

[0003] As the hydrolyzate of protein, peptides have shown significant advantages in regulating human physiological functions, enhancing immunity, promoting metabolism, and improving sleep quality due to their small molecular weight, easy absorption, and diverse biological activities. In recent years, with the in-depth research on peptides, peptides from different sources, such as black sesame peptides and black bean peptides, have gradually been favored by the market due to their unique nutritional value and health benefits. As a natural food rich in SOD, roxburgh not only contains rich nutrients such as vitamins and minerals, but also has significant antioxidant and health care effects due to its high SOD content. However, the development and utilization of roxburgh SOD in the market is currently limited to the extraction and application of a single component, and has failed to give full play to its synergistic effect with other functional ingredients.

[0004] At the same time, although there are many health products based on peptides on the market, there are few products that effectively combine Rosa roxburghii SOD with multiple peptides. This combination is expected to further enhance the health function of the product through the synergistic effect between different ingredients and meet consumers' demand for diversified and high-performance health products. Summary of the invention

[0005] The purpose of the invention is to provide a nutrient composition rich in roxburghii SOD and multiple peptides and a formula ratio thereof, so as to solve the shortcomings of various existing products.

[0006] In order to achieve the above-mentioned object, the present invention provides the following technical scheme: a nutrient composition rich in roxburgh SOD and multiple peptides and its formula ratio, comprising roxburgh SOD and fifteen plant peptides.

[0007] Furthermore, the fifteen plant peptides are black sesame peptide, black bean peptide, quinoa peptide, oat peptide, millet peptide, corn peptide, yam peptide, kudzu peptide, chestnut peptide, walnut peptide, sea buckthorn peptide, grape seed peptide, wolfberry peptide, jujube kernel peptide and selenium-enriched malt peptide.

[0008] Furthermore, the raw materials of the nutritional composition include, by weight: 5 parts of sea buckthorn SOD2, 5 parts of black sesame peptide, 5 parts of black bean peptide, 5 parts of quinoa peptide, 5 parts of oat peptide, 5 parts of millet peptide, 5 parts of corn peptide, 5 parts of yam peptide, 5 parts of kudzu root peptide, 5 parts of chestnut peptide, 5 parts of walnut peptide, 5 parts of sea buckthorn peptide, 5 parts of grape seed peptide, 5 parts of wolfberry peptide, 5 parts of jujube kernel peptide and 5 parts of selenium-rich malt peptide.

[0009] Compared with the prior art, the nutrient composition rich in roxburgh SOD and multiple plant peptides provided by the present invention and its formula ratio, by combining roxburgh SOD and fifteen plant peptides together, exerting the synergistic effect of multiple nutrients, providing comprehensive nutritional supplement and health care effects; all ingredients are derived from natural food materials, and are subjected to strict screening and extraction processes to ensure the safety and reliability of the product without side effects; SOD and peptide substances have the characteristics of small molecular weight and easy absorption, can be quickly absorbed and utilized by the human body, and improve the bioavailability of nutrients; it is suitable for people of all adult age groups, especially for middle-aged and elderly people, people with low immunity, people with poor sleep, patients with cardiovascular and cerebrovascular diseases, etc. BRIEF DESCRIPTION OF THE DRAWINGS

[0010] In order to more clearly illustrate the embodiments of the present application or the technical solutions in the prior art, the drawings required for use in the embodiments will be briefly introduced below. Obviously, the drawings described below are only some embodiments recorded in the present invention. For ordinary technicians in this field, other drawings can also be obtained based on these drawings.

[0011] Figure 1 The present invention provides a flow chart of a method for preparing a nutritional composition according to an embodiment of the present invention. DETAILED DESCRIPTION

[0012] In order to enable those skilled in the art to better understand the technical solution of the present invention, the present invention will be further described in detail below with reference to the accompanying drawings.

[0013] Embodiment 1:

[0014] See also Figure 1, a nutritional composition rich in roxburgh SOD and multiple peptides and its formula ratio, including roxburgh SOD and fifteen kinds of plant peptides, the fifteen kinds of plant peptides are black sesame peptide, black bean peptide, quinoa peptide, oat peptide, millet peptide, corn peptide, yam peptide, kudzu peptide, chestnut peptide, walnut peptide, sea buckthorn peptide, grape seed peptide, wolfberry peptide, jujube kernel peptide and selenium-enriched malt peptide; the raw materials of the nutritional composition include by weight: 25 parts of roxburgh SOD, 5 parts of black sesame peptide, 5 parts of black bean peptide, 5 parts of quinoa peptide, 5 parts of oat peptide, 5 parts of millet peptide, 5 parts of corn peptide, 5 parts of yam peptide, 5 parts of kudzu peptide, 5 parts of chestnut peptide, 5 parts of walnut peptide, 5 parts of sea buckthorn peptide, 5 parts of grape seed peptide, 5 parts of wolfberry peptide, 5 parts of jujube kernel peptide and 5 parts of selenium-enriched malt peptide.

[0015] The specific implementation method is that 25 portions of sea buckthorn SOD can not only meet the body's daily metabolic needs, but also avoid the high cost and side effects caused by excessive content.

[0016] Rosa roxburghii SOD (superoxide dismutase) has many benefits to the human body, mainly reflected in the following aspects:

[0017] Antioxidant and anti-aging: Seabuckthorn SOD is an important antioxidant enzyme that can remove harmful oxygen free radicals produced by organisms during metabolism, reduce their damage to cells, and thus delay the aging process; by removing free radicals, SOD can protect cells from damage and maintain the normal function and vitality of cells.

[0018] Regulating blood lipids and preventing cardiovascular diseases: SOD can enter blood vessels to remove deposited free radicals, allowing the deposited lipoproteins to return to a free state, thereby lowering blood lipids; by regulating blood lipid levels, SOD helps prevent the occurrence of cardiovascular diseases such as atherosclerosis.

[0019] Enhance immune function: Seabuckthorn SOD can increase the content of antioxidants in plasma and improve the body's antioxidant capacity; by enhancing the body's antioxidant capacity, SOD can indirectly enhance immune function and improve the body's ability to resist invasion by viruses and bacteria.

[0020] Anti-tumor effect: Rosa roxburghii SOD has a significant blocking effect on the synthesis of N-nitrosoproline, a strong carcinogen, in humans and animals; Rosa roxburghii juice has a significant inhibitory effect on the proliferation of human leukemia K562 tumor cells, and the active ingredients extracted from Rosa roxburghii also have a significant inhibitory effect on the proliferation of gastric cancer and endometrial adenocarcinoma cells;

[0021] In summary, Rosa roxburghii SOD has significant benefits in anti-oxidation, anti-aging, regulating blood lipids, enhancing immune function, anti-tumor, and preventing and treating diabetes. These benefits are mainly due to the powerful antioxidant capacity of SOD, which can remove harmful free radicals in the body and protect cells and tissues from damage.

[0022] Black sesame peptide, black bean peptide, quinoa peptide, oat peptide, millet peptide, corn peptide, yam peptide, kudzu peptide, chestnut peptide, walnut peptide, sea buckthorn peptide, grape seed peptide, wolfberry peptide, jujube kernel peptide and selenium-rich malt peptide, etc. These bioactive peptides extracted from natural ingredients each have unique amino acid composition and health benefits, and have many benefits to the human body. The following is a summary of the effects of these peptides:

[0023] Strengthen muscles: promote muscle growth and repair, improve athletic ability and physical fitness;

[0024] Assist in regulating blood sugar and blood lipids: It has the effect of lowering blood sugar and has a certain auxiliary therapeutic effect on diabetic patients; it reduces the cholesterol and triglyceride levels in the blood and prevents cardiovascular diseases;

[0025] Protect cardiovascular system: reduce blood cholesterol level and prevent cardiovascular diseases such as arteriosclerosis;

[0026] Moisturizes the intestines and promotes bowel health: promotes intestinal peristalsis and relieves constipation; maintains the balance of intestinal flora, promotes the growth of probiotics, and inhibits the reproduction of harmful bacteria;

[0027] Nourishes the liver and kidneys: It improves the symptoms caused by liver and kidney deficiency, replenishes the nutrients needed by the kidneys, improves kidney function, and nourishes the qi and stomach;

[0028] Improve immunity: enhance the vitality of immune cells and improve immune function;

[0029] Promote metabolism: Promote the discharge of metabolic waste in the body, help lose weight and improve obesity;

[0030] Antioxidant: remove free radicals, reduce cellular oxidative damage, and delay aging;

[0031] Nutritional supplement: provide essential amino acids and other nutrients;

[0032] Promote digestion and absorption: small molecular weight, direct absorption and utilization; improve the absorption and utilization rate of nutrients;

[0033] Improve sleep: regulate body secretion and improve sleep quality.

[0034] Although the materials used are not Chinese medicine ingredients, they are based on the principle of monarch, minister, assistant and envoy of the profound theory of traditional Chinese medicine. Rosa roxburghii SOD is the monarch, and the other fifteen kinds of plant peptides are the ministers. It is a pure plant new resource food that is convenient to carry and drink by combining the highest nutritional essence of food with modern technology. The nutritional composition combines Rosa roxburghii SOD with fifteen kinds of plant peptides from different sources, exerts the synergistic effect of multiple nutrients, and provides comprehensive nutrition and health care effects. The product is of natural origin, safe and reliable, easy to absorb, and suitable for a wide range of people. Through the verification of specific implementation methods and trial drinking, it is proved that the nutritional composition of the present invention has the effect of significantly improving immunity and anti-aging, and has broad market prospects and application value.

[0035] The following are the advantages of the organic combination of fifteen plant peptides and the complementary amino acids:

[0036] 1. Comprehensive and rich nutrition

[0037] These fifteen peptides are derived from different natural ingredients, covering multiple types of plants. Black sesame peptides, black bean peptides, etc. come from cereals and beans, are rich in a variety of essential amino acids for the human body, and provide the body with a high-quality source of protein. Seabuckthorn peptides, grape seed peptides, etc. are extracted from fruits rich in antioxidants. While providing amino acids, they also bring rich bioactive substances. This diverse source enables the nutritional composition to provide comprehensive nutritional support and meet the human body's needs for various nutrients.

[0038] 2. Amino acid complementation enhances nutritional value

[0039] Different peptides contain different types and proportions of amino acids. For example, oat peptides are rich in lysine, while corn peptides contain higher levels of tryptophan. By organically combining these fifteen peptides, amino acid complementarity can be achieved. When the amino acids lacking in certain peptides can be supplemented in other peptides, the overall amino acid composition is closer to the ideal pattern required by the human body, thereby improving the bioavailability of protein. This advantage of amino acid complementarity helps maintain the body's normal physiological functions, promote growth and development, repair tissue damage, etc.

[0040] 3. Synergistic effects to achieve multiple physiological effects

[0041] 1. Enhance immunity: Lycium barbarum peptides, yam peptides and other nourishing peptides can regulate the immune system, and the selenium in selenium-rich malt peptides also helps to enhance the activity of immune cells. The combined effect of multiple peptides can significantly improve the body's immunity and reduce the risk of disease.

[0042] 2. Antioxidant and anti-aging: Grape seed peptide and sea buckthorn peptide also have strong antioxidant capacity. They work synergistically with sea buckthorn SOD to more effectively remove free radicals in the body, reduce oxidative damage, delay cell aging, and maintain skin elasticity and physical health.

[0043] 3. Promote brain development and improve sleep: Walnut peptide promotes brain development and memory. Jujube peptide helps improve sleep quality. The combination of the two provides double protection for the health of the nervous system.

[0044] 4. Protect the liver and stomach: Corn peptide can promote alcohol metabolism and protect the liver. Millet peptide and yam peptide have a good regulating effect on gastrointestinal function. Multiple peptides work together to protect the health of the digestive system and liver.

[0045] The perfect combination of sea buckthorn SOD and peptide acts on every cell in the five internal organs and eight systems of the human body, activating, repairing, improving and promoting the body's functions and working ability in all aspects!

[0046] Embodiment 2:

[0047] See also Figure 1 This embodiment provides a technical solution based on the first embodiment: a nutritional composition rich in roxburghii SOD and multiple peptides and its formula ratio, and its preparation method specifically comprises the following steps:

[0048] S1, raw material cleaning: the pear, black sesame, black bean, quinoa, oat, millet, corn, yam, kudzu root, chestnut, walnut, sea buckthorn, grape seed, wolfberry, spiny jujube kernel and selenium-enriched malt are cleaned by a cleaning device, the cleaning time of the cleaning device is 5-10min, and impurities on the surface of the raw materials are removed. After the cleaning, the pear, black sesame, black bean, quinoa, oat, millet, corn, yam, kudzu root, chestnut, walnut, sea buckthorn, grape seed, wolfberry, spiny jujube kernel and selenium-enriched malt are taken out and placed on a filter to drain and dry;

[0049] S2. Extraction of sea buckthorn SOD: SOD is extracted from sea buckthorn by biotechnology, and is purified and concentrated to ensure the activity and purity of sea buckthorn SOD; the biotechnology includes raw material processing, enzymatic hydrolysis-assisted extraction and extract preparation steps, and the purification step includes preliminary purification, ion exchange chromatography and gel filtration chromatography; the enzymatic agent used in the enzymatic hydrolysis-assisted extraction step is a mixture of cellulase and pectinase.

[0050] The specific implementation method is as follows: the cleaned roxburghii is de-cored, crushed, and ground into powder or slurry; a mixture of cellulase and pectinase is selected for auxiliary extraction, and these enzymes can destroy the cell wall of the roxburghii, so that effective ingredients such as SOD are more easily released into the extract; the enzymatically hydrolyzed roxburghii is mixed with water for extraction to ensure sufficient release of SOD;

[0051] After the extraction is completed, the solid residue is removed by filtration to obtain an extract containing SOD, and then the extract is centrifuged to remove suspended matter and impurities therein, thereby further improving the purity of SOD; the extract is chromatographed using ion exchange resins, and SOD is separated and purified based on the difference in charge properties between SOD and other components; small molecular impurities are further removed by gel filtration chromatography to improve the purity of SOD, and gel filtration chromatography utilizes the sieving effect of gel particles to separate and purify SOD based on molecular size;

[0052] The purified SOD-containing extract is concentrated by ultrafiltration to effectively remove water from the solution while maintaining the activity of SOD, thereby increasing the concentration of SOD.

[0053] S3. Preparation of fifteen peptides: extracting peptide substances from black sesame, black beans, quinoa, oats, millet, corn, yam, kudzu root, chestnut, walnut, sea buckthorn, grape seeds, wolfberry, jujube kernel and selenium-enriched malt respectively, and obtaining high-purity peptides with a molecular weight of 500-800 Da by enzymatic hydrolysis and purification process; selecting a suitable enzymatic hydrolysis system according to the characteristics of different raw materials during the enzymatic hydrolysis process, mixing the enzymatic enzyme with the food powder at a temperature of 45°C to 55°C and a pH value of 7.0 to 11.0, and performing enzymatic hydrolysis reaction, After the reaction time is 2 to 4 hours, an enzymolysis solution is obtained; the enzymolysis enzyme includes papain, bromelain, alkaline protease, neutral protease, trypsin, pepsin or pronase; the purification process includes: centrifuging the enzymolysis solution to remove insoluble matter to obtain a supernatant; using membrane separation technology to preliminarily separate and purify the supernatant to remove large molecular impurities and some small molecular impurities; further using gel filtration chromatography or ion exchange chromatography separation and purification technology to finely separate peptide substances to obtain high-purity peptide substances.

[0054] The specific implementation method is to select a suitable enzymatic hydrolysis system according to the chemical composition and physical properties of each food material. For protein-rich food materials, such as black sesame, black beans, quinoa, oats, millet, walnuts and chestnuts, papain, bromelain and alkaline protease are selected; for food materials containing more cellulose, such as oats, quinoa, black beans, corn, yam and kudzu root, neutral protease, trypsin, pepsin and pronase need to be added, the enzymatic hydrolyzate is centrifuged to remove insoluble matter to obtain a supernatant; membrane separation technology is used to perform preliminary separation and purification of the supernatant to remove large molecular impurities and some small molecular impurities; gel filtration chromatography or ion exchange chromatography separation and purification technology is further used to finely separate peptide substances to obtain high-purity peptide substances.

[0055] The gel filtration chromatography method is that the porous network structure of the gel particles allows small molecules to enter its interior, while large molecules are excluded from the outside. When a sample solution containing a variety of molecules of different sizes passes through the gel layer, small molecules can enter the pores inside the gel particles and flow along the pores, so their flow path is longer and their migration speed is slower; while large molecules cannot enter the interior of the gel particles and can only flow in the gaps between the gel particles, so their flow path is shorter and their migration speed is faster. Therefore, during the elution process, large molecules will be eluted first, and small molecules will be eluted later, thereby achieving molecular separation.

[0056] Ion exchange chromatography is a chromatographic method that uses ion exchangers as stationary phases and performs separation based on the difference in binding strength between component ions in the mobile phase and the counter ions on the exchanger when they are reversibly exchanged. Ion exchangers are usually composed of charged resins or cellulose. Those with negative charges are called anion exchange resins, and those with positive charges are called cation resins. The solute ions in the sample are exchanged with the ions on the ion exchanger. Since different solute ions have different affinities and binding conditions with the ionized groups on the ion exchanger, when the eluent flows through, the ions in the sample will be eluted in order according to the strength of the binding force.

[0057] S4, raw material mixing: SOD extracted from roxburghii and 15 peptides respectively extracted from black sesame, black bean, quinoa, oat, millet, corn, yam, kudzu root, chestnut, walnut, sea buckthorn, grape seed, wolfberry, jujube kernel and selenium-enriched malt are mixed evenly in proportion to obtain a nutritional composition;

[0058] S5, packaging and storage: At this time, the nutritional composition of S4 is taken out and made into a powder for easy consumption. The nutritional composition is then sterilized using a sterilization device, and then bagged through packaging bags, and then labels are affixed to the packaging bags, and then stored in the warehouse using a conveying device.

[0059] Embodiment three:

[0060] This embodiment provides a technical solution based on the second embodiment: the activity of SOD extracted from Rosa roxburghii is 20000-40000u.

[0061] The above description is only by way of illustration of certain exemplary embodiments of the present invention. It is undoubted that those skilled in the art can modify the described embodiments in various ways without departing from the spirit and scope of the present invention. Therefore, the above drawings and descriptions are illustrative in nature and should not be construed as limiting the scope of protection of the claims of the present invention.

Claims

1. A nutritional composition rich in roxburghii SOD and multiple peptides and its formula ratio, characterized in that: The nutritional composition comprises roxburghii SOD and fifteen plant peptides.

2. A nutritional composition rich in roxburghii SOD and multiple peptides and its formula ratio according to claim 1, characterized in that: The fifteen peptides are black sesame peptide, black bean peptide, quinoa peptide, oat peptide, millet peptide, corn peptide, yam peptide, kudzu peptide, chestnut peptide, walnut peptide, sea buckthorn peptide, grape seed peptide, wolfberry peptide, jujube kernel peptide and selenium-enriched malt peptide.

3. A nutritional composition rich in roxburghii SOD and multiple peptides and its formula ratio according to claim 2, characterized in that: The raw materials of the nutritional composition include, by weight: 25 parts of roxburghii SOD, 5 parts of black sesame peptide, 5 parts of black bean peptide, 5 parts of quinoa peptide, 5 parts of oat peptide, 5 parts of millet peptide, 5 parts of corn peptide, 5 parts of yam peptide, 5 parts of kudzu root peptide, 5 parts of chestnut peptide, 5 parts of walnut peptide, 5 parts of sea buckthorn peptide, 5 parts of grape seed peptide, 5 parts of wolfberry peptide, 5 parts of jujube kernel peptide and 5 parts of selenium-enriched malt peptide.

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