Ultrafiltration perfusion device and ultrafiltration perfusion system

Abstract

The invention relates to the technical field of medical equipment, and aims to provide an ultrafiltration perfusion device and an ultrafiltration perfusion system. The ultrafiltration perfusion device is simple in function, only performs ultrafiltration perfusion treatment on a patient, and is simple in structure, easy to operate and convenient to carry. The ultrafiltration perfusion device comprises a box body, a blood guide piece and an ultrafiltration perfusion device, the blood guide part is arranged in the box body, an inlet of the blood guide part is communicated with one end of the blood supply device, an outlet of the blood guide part is connected with a liquid inlet of the ultrafiltration perfusion device, a liquid outlet of the ultrafiltration perfusion device is connected with the other end of the blood supply device, and the ultrafiltration perfusion device is used for performing ultrafiltration and perfusion treatment on blood extracted by the blood guide part. The problems that in the prior art, CRRT equipment is large in size and weight and tedious in operation, a patient cannot carry the CRRT equipment for transferring, excessive treatment can be caused to the patient, and the economic burden is increased are solved.

Description

Technical Field

[0001] The present invention relates to the technical field of medical equipment, and in particular to an ultrafiltration perfusion device and an ultrafiltration perfusion system. Background Art

[0002] Most critically ill patients with cardiopulmonary insufficiency who are assisted by ECMO (Extracorporeal Membrane Oxygenation) are accompanied by excessive fluid load, severe inflammatory response and even sepsis. The blood needs to be ultrafiltered to remove water. If there is a severe inflammatory response, perfusion is required to absorb inflammatory factors to reduce the inflammatory response and reduce the risk of infection.

[0003] At present, CRRT (continuous renal replacement therapy) equipment is usually used for ultrafiltration perfusion therapy. There are many treatment modes of CRRT equipment, such as ultrafiltration, perfusion, dialysis, etc. The CRRT equipment includes a blood pump and four liquid pumps. The blood in the patient's body is drawn out to the device corresponding to the treatment mode through the blood pump, and then the liquid with the corresponding treatment function is introduced into different devices for corresponding treatment through the corresponding liquid pump. However, due to the diversity and complexity of CRRT treatment modes, the size and weight of CRRT equipment are too large, and the pipelines and operations are cumbersome. When the patient needs to be examined or operated, the CRRT equipment cannot be transported during the transportation process and the CRRT treatment is forced to be interrupted. If the connection between the CRRT equipment and the patient is interrupted, blood coagulation and thrombosis will form in the CRRT pipeline, so that the machine is forced to end the treatment, the life of the consumables is shortened and blood is wasted. In addition, when the patient only undergoes ultrafiltration perfusion treatment or some relatively simplified treatments, it will cause a waste of medical resources (consumables, medical workload), lead to overtreatment, and increase the risk of patient treatment and economic burden. Summary of the invention

[0004] Therefore, the technical problem to be solved by the present invention is to overcome the defects of the CRRT equipment in the prior art, such as large size and weight, cumbersome operation, inability of patients to carry the CRRT machine for transportation, excessive treatment of patients, and increased economic burden, thereby providing an ultrafiltration perfusion device and ultrafiltration perfusion system with simple functions, which only performs ultrafiltration perfusion treatment on patients, and has a simple structure, simple operation, and is easy to carry.

[0005] In order to solve the above problems, the present invention provides an ultrafiltration perfusion device, comprising:

[0006] Box body;

[0007] A blood-drawing piece is arranged in the box body, and an inlet of the blood-drawing piece is connected to one end of the blood supply device;

[0008] The ultrafiltration perfusion device has an outlet of the blood drawing component connected to a liquid inlet of the ultrafiltration perfusion device, and a liquid outlet of the ultrafiltration perfusion device connected to the other end of the blood supply device. The ultrafiltration perfusion device is used to perform ultrafiltration and perfusion treatment on the blood drawn by the blood drawing component.

[0009] Optionally, the ultrafiltration perfusion device includes: a tube body, the inner cavity of the tube body includes an ultrafiltration chamber and a perfusion chamber separated from each other, the ultrafiltration chamber inlet is connected to the liquid inlet, the ultrafiltration chamber outlet is connected to the perfusion chamber inlet, and the perfusion chamber outlet is connected to the liquid outlet.

[0010] Optionally, a water filter is provided in the ultrafiltration chamber, and a side wall of the ultrafiltration chamber has an ultrafiltrate outlet.

[0011] Optionally, there are two ultrafiltrate outlets, one of which is close to the ultrafiltration chamber inlet, and the other is close to the ultrafiltration chamber outlet.

[0012] Optionally, an adsorption structure is provided in the perfusion chamber.

[0013] Optionally, the adsorption structure includes an adsorption medium and a filter screen arranged at the outlet of the perfusion chamber.

[0014] Optionally, a power supply device and a driving device are provided in the box body, the power supply device is electrically connected to the driving device, the driving end of the driving device is connected to the blood-drawing piece, and the control unit is communicatively connected to the driving device.

[0015] Optionally, it also includes a control unit, a display panel and a flow rate adjustment key, the control unit is arranged in the box body, the display panel and the flow rate adjustment key are arranged on the side wall of the box body, the flow rate adjustment key is communicatively connected to the control unit, and the control unit is communicatively connected to the display panel and the driving device.

[0016] Optionally, the inlet of the blood guide piece and one end of the blood supply device, as well as the outlet of the ultrafiltration perfusion device and the other end of the blood supply device are connected via an infusion pipeline, and antibacterial and anticoagulant substances are provided in the infusion pipeline.

[0017] An ultrafiltration perfusion system, comprising the ultrafiltration perfusion device, and also comprising an ECMO device, wherein the ECMO device comprises an ECMO pump and an oxygenator arranged in sequence along the blood flow direction, the inlet of the blood guide is connected to the rear end of the ECMO pump, and the liquid outlet of the ultrafiltration perfusion device is connected to the front end of the ECMO pump;

[0018] Or the inlet of the blood guide is connected to the rear end of the oxygenator, and the outlet of the ultrafiltration cartridge is connected to the front end of the ECMO pump;

[0019] Alternatively, the inlet of the blood-introducing component is connected to the rear end of the oxygenator, and the liquid outlet of the ultrafiltration cartridge is connected to the front end of the oxygenator.

[0020] The present invention has the following advantages:

[0021] 1. The ultrafiltration perfusion device provided by the present invention comprises a box body, a blood-drawing piece and an ultrafiltration perfusion device. The blood-drawing piece is arranged in the box body, and the inlet of the blood-drawing piece is connected to one end of the blood supply device, the liquid inlet of the ultrafiltration perfusion device is connected to the outlet of the blood-drawing piece, and the liquid outlet of the ultrafiltration perfusion device is connected to the other end of the blood supply device. Blood is drawn into the ultrafiltration perfusion device through the blood-drawing piece, and ultrafiltration and perfusion are performed in the ultrafiltration perfusion device to filter the overload liquid in the blood and adsorb inflammatory factors. This ultrafiltration perfusion device has simple functions, low manufacturing costs, and low economic burden on patients. It also has a simple structure and is easy to carry and transport. The transportation process is safe and simple, and does not affect most of the patient's autonomous activities.

[0022] 2. The ultrafiltration perfusion device provided by the present invention comprises a tube body, the inner cavity of the tube body has an ultrafiltration chamber and a perfusion chamber separated from each other, the ultrafiltration chamber inlet is connected to the liquid inlet, the ultrafiltration chamber outlet is connected to the perfusion chamber inlet, and the perfusion chamber outlet is connected to the liquid outlet. After the blood enters the ultrafiltration chamber, it passes through the ultrafiltration chamber and the perfusion chamber in turn, and is subjected to ultrafiltration and perfusion treatments correspondingly. This ultrafiltration chamber can integrate the ultrafiltration and perfusion functions together, has a simple structure and strong functionality, and the ultrafiltration chamber and the perfusion chamber are separated from each other and do not interfere with each other, so the treatment effect is better.

[0023] 3. The ultrafiltration perfusion device provided by the present invention has a power supply device and a driving device in the box body, the power supply device supplies power to the driving device, and the driving device drives the blood-drawing device to work. With the power supply device, the ultrafiltration perfusion device does not need to be plugged in all the time, so it is easy to transport and carry.

[0024] 4. The ultrafiltration perfusion device provided by the present invention also includes a control unit, a display panel and a flow rate adjustment key. The control unit is arranged in the box body, the display panel and the flow rate adjustment key are arranged on the side wall of the box body, the flow rate adjustment key is connected to the control unit in communication, and the control unit is connected to the display panel and the drive device in communication. The output speed of the drive device can be controlled by the flow rate adjustment key and the control unit, thereby adjusting the blood drawing speed of the blood drawing device, which can meet the needs of different treatment modes, and can also avoid air intake at the interface between the blood drawing device and the blood supply device, thereby reducing the risk of patient treatment.

[0025] 5. In the ultrafiltration perfusion device provided by the present invention, the inlet of the blood guide piece is connected to one end of the blood supply device, and the outlet of the ultrafiltration perfusion device is connected to the other end of the blood supply device through an infusion pipeline. Antibacterial and anticoagulant substances are arranged in the infusion pipeline, which can effectively prevent blood coagulation and thrombus formation in the infusion pipeline, extend the service life of the infusion pipeline, and save medical expenses.

[0026] 6. The ultrafiltration perfusion system provided by the present invention includes an ultrafiltration perfusion device and an ECMO device, and the ECMO device includes an ECMO pump and an oxygenator arranged in sequence along the direction of blood flow. There are three ways to connect the ultrafiltration perfusion device to the ECMO device: the inlet of the blood-drawing piece is connected to the rear end of the ECMO pump, and the outlet of the ultrafiltration perfusion device is connected to the front end of the ECMO pump; or the inlet of the blood-drawing piece is connected to the rear end of the oxygenator, and the outlet of the ultrafiltration perfusion device is connected to the front end of the ECMO pump; or the inlet of the blood-drawing piece is connected to the rear end of the oxygenator, and the outlet of the ultrafiltration perfusion device is connected to the front end of the ECMO pump; or the inlet of the blood-drawing piece is connected to the rear end of the oxygenator, and the outlet of the ultrafiltration perfusion device is connected to the front end of the oxygenator. By connecting the ultrafiltration perfusion device in parallel to the ECMO device, blood ultrafiltration and perfusion can be performed simultaneously for patients treated with ECMO equipment. Compared with the existing CRRT machine for blood ultrafiltration and perfusion, this ultrafiltration perfusion system has low usage costs, and the equipment is small in size, easy to transport and carry, and will not affect the patient's activities. BRIEF DESCRIPTION OF THE DRAWINGS

[0027] In order to more clearly illustrate the specific implementation methods of the present invention or the technical solutions in the prior art, the drawings required for use in the specific implementation methods or the description of the prior art will be briefly introduced below. Obviously, the drawings described below are some implementation methods of the present invention. For ordinary technicians in this field, other drawings can be obtained based on these drawings without paying creative work.

[0028] Figure 1 is a schematic diagram of an ultrafiltration perfusion device of the present invention;

[0029] Figure 2 It is a schematic diagram of a box body and a blood guide member in the ultrafiltration perfusion device of the present invention;

[0030] Figure 3 It is a schematic diagram of the ultrafiltration perfusion device in the ultrafiltration perfusion device of the present invention.

[0031] Description of reference numerals:

[0032] 1. Box body, 101. Base, 102. Cover, 103. Buckle, 104. Handle, 105. Connector;

[0033] 2. Blood-drawing parts;

[0034] 3. Ultrafiltration perfusion device, 301. liquid inlet, 302. liquid outlet, 303. tube body, 3031. ultrafiltration chamber, 3032. perfusion chamber, 304. water filter, 305. ultrafiltrate outlet, 306. adsorption medium, 307. filter screen, 308. partition;

[0035] 4. Display panel;

[0036] 5. Flow rate adjustment button;

[0037] 6. Infusion pipeline. DETAILED DESCRIPTION

[0038] The technical solution of the present invention will be described clearly and completely below in conjunction with the accompanying drawings. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0039] In the description of the present invention, it should be noted that the terms "center", "upper", "lower", "left", "right", "vertical", "horizontal", "inner", "outer", etc., indicating the orientation or positional relationship, are based on the orientation or positional relationship shown in the drawings, and are only for the convenience of describing the present invention and simplifying the description, rather than indicating or implying that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore cannot be understood as limiting the present invention. In addition, the terms "first", "second", and "third" are used for descriptive purposes only, and cannot be understood as indicating or implying relative importance.

[0040] In the description of the present invention, it should be noted that, unless otherwise clearly specified and limited, the terms "installed", "connected", and "connected" should be understood in a broad sense, for example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be a direct connection, or it can be indirectly connected through an intermediate medium, or it can be the internal communication of two components. For ordinary technicians in this field, the specific meanings of the above terms in the present invention can be understood according to specific circumstances.

[0041] In addition, the technical features involved in the different embodiments of the present invention described below can be combined with each other as long as they do not conflict with each other.

[0042] like Figure 1 As shown, it is a preferred embodiment of the ultrafiltration perfusion device of the present invention. This ultrafiltration perfusion device can be applied to critically ill patients who are treated with ECMO. The ultrafiltration perfusion device can be used to ultrafilter and perfuse the patient's blood. Compared with the CRRT machine, this ultrafiltration perfusion device has simple functions and only performs ultrafiltration and perfusion treatment on the patient. It will not cause overtreatment when used and has low cost. The economic burden on the patient is relatively small. In addition, the ultrafiltration perfusion device has a simple structure, a small size, and is easy to carry and transport.

[0043] The above-mentioned ultrafiltration perfusion device includes: a box body 1, a blood-drawing piece 2 and an ultrafiltration perfusion device 3. The blood-drawing piece 2 is arranged in the box body 1. The inlet of the blood-drawing piece 2 is connected to one end of the blood supply device, the outlet of the blood-drawing piece 2 is connected to the liquid inlet 301 of the ultrafiltration perfusion device 3, and the liquid outlet 302 of the ultrafiltration perfusion device 3 is connected to the other end of the blood supply device. The blood-drawing piece 2 draws out part of the blood in the blood supply device and draws it into the ultrafiltration perfusion device 3. The ultrafiltration perfusion device 3 is used to ultrafilter and perfuse the blood drawn out by the blood-drawing piece 2, and then return the treated blood to the blood supply device. The ultrafiltration perfusion device only realizes ultrafiltration and perfusion effects, has simple functions, and the blood-drawing piece 2 is arranged in the box body 1. The volume of the box body 1 and the ultrafiltration perfusion device 3 is small, which is convenient for carrying and transportation. The blood supply device can be a device that can draw blood from the human body, such as an ECMO pump. The ECMO pump can draw blood from the human body and then send it back to the human body. The inlet of the blood drawing piece 2 is connected to the end of the ECMO pump that returns blood to the human body, and the liquid outlet 302 of the ultrafiltration perfusion device 3 is connected to the end of the ECMO pump that draws blood from the human body. In addition, the ultrafiltration perfusion device can also be directly connected to the human body, that is, the human body is regarded as a blood supply device, the inlet of the blood drawing piece 2 is connected to the deep vein of the human body to draw blood, and enter the ultrafiltration perfusion device 3 for ultrafiltration and perfusion, and the liquid outlet 302 of the ultrafiltration perfusion device 3 is connected to the deep vein of the human body to return the treated blood to the human body.

[0044] Further, such as Figure 2 As shown, the box body 1 includes a base 101 and a cover 102, one end of the cover 102 is hinged to the base 101, and the cover 102 can be covered on the base 101. After the cover 102 is covered on the base 101, it is connected by a buckle 103 arranged on the other end of the cover 102 and the base 101. A handle 104 is also arranged on the cover 102 for easy carrying. When the box body 1 needs to be carried and moved, the cover 102 and the base 101 are connected together by the buckle 103, and the box body 1 can be moved by hand by carrying the handle 104. The buckle 103 can be provided to prevent the base 101 and the cover 102 from separating when the box body 1 is carried. In other embodiments, the number of the buckles 103 can also be two, three, etc. Other types of buckles can also be used to lock the base 101 and the cover 102, such as push-pull buckles, twisting buckles, etc., and padlocks and other lock structures can also be used.

[0045] The blood-drawing component 2 is arranged on the base 101. In this embodiment, the blood-drawing component 2 is preferably a roller pump. The blood-drawing blood path of the roller pump is arranged in a U-shape. The blood-drawing blood path is arranged in a slot of the base 101 and is fixed by a clamping component 105 on the slot. The two ends of the blood-drawing blood path are the inlet and outlet of the blood-drawing component 2.

[0046] In addition, the side walls of the box body 1 are also provided with nuts for fixing the box body 1, so as to facilitate the box body 1 to be fixed on some frames or walls.

[0047] A power supply device and a driving device are provided in the box body 1, the power supply device is electrically connected to the driving device, and the driving end of the driving device is connected to the blood-drawing member 2. Specifically, in this embodiment, the power supply device and the driving device are arranged in the base 101. The power supply device is a power source, which can be plugged in and can store electrical energy when plugged in, so the power supply device can also be used when the power is off. When the power is off, the electrical energy stored in the power supply device can power the driving device. The driving device is preferably a motor, which can drive the roller pump to rotate.

[0048] The ultrafiltration perfusion device also includes a control unit, a display panel 4 and a flow rate adjustment key 5. The control unit is arranged in the box body 1, and the display panel 4 and the flow rate adjustment key 5 are arranged on the side wall of the box body 1, and the side wall is inclined to facilitate people to observe the information on the display panel 4. The flow rate adjustment key 5 is connected to the control unit in communication, and the control unit is connected to the display panel 4 and the drive device in communication. In this embodiment, the flow rate adjustment key 5 is a knob type. By rotating the flow rate adjustment key 5, the control unit can be controlled to change the rotation speed of the drive device, thereby changing the flow rate when the blood drawing component 2 draws blood. In other embodiments, the flow rate adjustment key 5 can also use a press-type button, set multiple gears in advance, and adjust a certain rotation speed each time it is pressed. The display panel 4 can display some basic parameters, such as the power of the power supply device, the rotation speed of the blood drawing component 2, the blood flow rate, etc.

[0049] The inlet of the blood-drawing component 2 and one end of the blood supply device, as well as the outlet of the ultrafiltration cartridge 3 and the other end of the blood supply device, are connected via an infusion pipe 6. The infusion pipe 6 is a flexible pipe that is easy to install and connect. Antibacterial and anticoagulant substances are provided in the infusion pipe 6 to prevent blood from coagulating during circulation, thereby causing device failure. In this embodiment, an anticoagulant and antibacterial substance coating is provided on the wall of the infusion pipe 6, and the outlet of the blood-drawing component 2 and the inlet of the ultrafiltration cartridge 3 are also connected via the infusion pipe 6. In other embodiments, the outlet of the blood-drawing component 2 and the inlet of the ultrafiltration cartridge 3 may also be directly connected without passing through the infusion pipe 6.

[0050] like Figure 3 As shown, the ultrafiltration perfusion device 3 includes: a tube body 303, the inner cavity of the tube body 303 includes an ultrafiltration chamber 3031 and a perfusion chamber 3032 separated from each other, the ultrafiltration chamber inlet is connected to the liquid inlet, the ultrafiltration chamber outlet is connected to the perfusion chamber inlet, and the perfusion chamber outlet is connected to the liquid outlet. Specifically, in this embodiment, the tube body 303 is a hollow circular tube, and detachable end caps are provided at both ends of the circular tube, and the two end caps are respectively provided with a liquid inlet 301 and a liquid outlet 302. In other embodiments, the tube body 303 can also be a square tube or a tube of other shapes. And in normal use, the ultrafiltration perfusion device 3 is in a vertical state, the lower end is the ultrafiltration chamber inlet, and the upper end is the ultrafiltration chamber outlet. This ultrafiltration perfusion device 3 can concentrate the ultrafiltration and perfusion functions together and perform them simultaneously, and the ultrafiltration chamber and the perfusion chamber are separated from each other and do not interfere with each other, so the treatment effect is better.

[0051] A partition plate 308 is provided inside the tube body 303. In this embodiment, the partition plate 308 is integrally formed with the tube body 303. The two sides of the partition plate 308 are the ultrafiltration chamber 3031 and the perfusion chamber 3032. A through hole is opened on the partition plate 308, so that the ultrafiltration chamber outlet is connected with the perfusion chamber inlet.

[0052] In other embodiments, the partition plate 308 may not be integrally formed with the tube body 303, that is, the partition plate 308 is installed independently, so that the partition plates 308 with holes of different apertures can be manufactured. The selection of different partition plates 308 can adjust the flow area of ​​blood, thereby changing the rate of blood ultrafiltration and perfusion.

[0053] A water filter 304 is provided in the ultrafiltration chamber 3031, one end of the water filter 304 is connected to the liquid inlet 301, and the other end is connected to the through hole on the partition plate 308. The side wall of the ultrafiltration chamber 3031 has an ultrafiltrate outlet 305. Specifically, in this embodiment, the water filter 304 is an antibacterial and anticoagulant hollow fiber semipermeable membrane, and an antibacterial and anticoagulant coating can also be provided on the inner side of the water filter 304. There are two ultrafiltrate outlets 305, and they are staggered, which can improve the liquid discharge efficiency of the ultrafiltrate. One of the ultrafiltrate outlets 305 is close to the ultrafiltration chamber inlet, and the other ultrafiltrate outlet 305 is close to the ultrafiltration chamber outlet. After the blood enters the water filter 304 from the liquid inlet 301, it flows to one side of the through hole, and under the action of the semipermeable membrane, the excess water in the blood is precipitated from the inner side of the semipermeable membrane to the outer side, and discharged through the ultrafiltrate outlet 305, so as to achieve the blood ultrafiltration effect.

[0054] An adsorption structure is provided in the perfusion chamber 3032, and the adsorption structure includes an adsorption medium 306 and a filter 307 provided at the outlet of the perfusion part, wherein the adsorption medium 306 includes a synthetic resin adsorbent and a liquid containing antibacterial and anticoagulant substances, and the liquid can be sterile water for injection or physiological saline, and the synthetic resin adsorbent is in a granular form, which can adsorb inflammatory factors in the blood to achieve blood perfusion. The filter 307 can filter the synthetic resin adsorbent, so that the blood is discharged from the liquid outlet 302 through the filter 307, while the adsorption medium 306 is retained in the perfusion chamber 3032.

[0055] This embodiment also provides an ultrafiltration perfusion system, including an ultrafiltration perfusion device and an ECMO device, wherein the structure of the ultrafiltration perfusion device is the same as that of the ultrafiltration perfusion device in the above embodiment, so it will not be repeated.

[0056] ECMO equipment includes an ECMO pump and an oxygenator that are arranged in sequence along the direction of blood flow. The ECMO equipment includes an ECMO pump and an oxygenator. The blood is drawn out of the human body through the ECMO pump, the blood is introduced through the ECMO pump, and then the ECMO pump sends the blood to the oxygenator for blood oxygenation, and finally the blood is transported back to the human body. The front end of the ECMO pump is negative pressure to introduce blood, and the back end is positive pressure to transport blood to the oxygenator.

[0057] There are three ways to connect the ultrafiltration perfusion device to the ECMO equipment: the inlet of the blood draw piece is connected to the rear end of the ECMO pump, and the outlet of the ultrafiltration perfusion device is connected to the front end of the ECMO pump; or the inlet of the blood draw piece is connected to the rear end of the oxygenator, and the outlet of the ultrafiltration perfusion device is connected to the front end of the ECMO pump; or the inlet of the blood draw piece is connected to the rear end of the oxygenator, and the outlet of the ultrafiltration perfusion device is connected to the front end of the oxygenator.

[0058] In this embodiment, the inlet of the blood-drawing component is connected to the rear end of the ECMO pump, and the outlet of the ultrafiltration perfusion device is connected to the front end of the ECMO pump. The ECMO pump is a blood supply device, and one end of the blood supply device connected to the inlet of the blood-drawing component 2 is the rear end of the ECMO pump, and the other end of the blood supply device connected to the outlet 302 of the ultrafiltration perfusion device 3 is the front end of the ECMO pump. The ultrafiltration perfusion device is equivalent to being connected in parallel to the ECMO pump. The blood-drawing speed of the ECMO pump is greater than the blood-drawing speed of the blood-drawing component 2. The blood-drawing component 2 is used to introduce part of the blood drawn by the ECMO pump from the rear end of the ECMO pump into the ultrafiltration perfusion device 3 for ultrafiltration and perfusion. The treated blood is then incorporated into the front end of the ECMO pump and finally returns to the human body.

[0059] In other embodiments, the connection method between the ultrafiltration perfusion device and the ECMO equipment can also be selected as follows: the inlet of the blood draw piece is connected to the rear end of the oxygenator, and the liquid outlet of the ultrafiltration perfusion device is connected to the front end of the ECMO pump; or the inlet of the blood draw piece is connected to the rear end of the oxygenator, and the liquid outlet of the ultrafiltration perfusion device is connected to the front end of the oxygenator.

[0060] The working process of the ultrafiltration perfusion system provided in this embodiment is described as follows:

[0061] The front end of the ECMO pump is connected to the human vena cava to draw blood, and then the blood is transported from the back end of the ECMO pump to the oxygenator for oxygenation. The blood is then transported from the oxygenator back to the human body.

[0062] In the process of blood flowing from the front end of the ECMO pump to the back end of the ECMO pump, the blood guide 2 will introduce a small amount of blood from the back end of the ECMO pump into the ultrafiltration perfusion device, and under the action of the blood guide 2, the blood will be transported to the ultrafiltration perfusion device 3. After the blood enters from the liquid inlet 301, under the action of the osmotic pressure of the semipermeable membrane, the overloaded liquid in the blood will precipitate to the outside of the semipermeable membrane. Then the filtrate is discharged from the ultrafiltration perfusion device 3 from the ultrafiltrate outlet 305.

[0063] After ultrafiltration, the blood enters the perfusion chamber 3032 from the through hole on the partition plate 308. Under the action of the adsorption medium 306, the inflammatory factors in the blood are adsorbed away. Then, after the blood is filtered through the filter 307, it is discharged from the liquid outlet 302, enters the front end of the ECMO pump, and finally returns to the human body.

[0064] Obviously, the above embodiments are merely examples for the purpose of clear explanation, and are not intended to limit the implementation methods. For those skilled in the art, other different forms of changes or modifications can be made based on the above description. It is not necessary and impossible to list all the implementation methods here. The obvious changes or modifications derived therefrom are still within the scope of protection of the present invention.

Claims

1. An ultrafiltration perfusion device, characterized in that: include: Box body (1); A blood-drawing piece (2) is arranged in the box body (1), and an inlet of the blood-drawing piece (2) is connected to one end of a blood supply device; The ultrafiltration perfusion device (3) has an outlet of the blood drawing component (2) connected to a liquid inlet (301) of the ultrafiltration perfusion device (3), and a liquid outlet (302) of the ultrafiltration perfusion device (3) connected to the other end of the blood supply device. The ultrafiltration perfusion device (3) is used to perform ultrafiltration and perfusion treatment on the blood drawn by the blood drawing component (2).

2. The ultrafiltration perfusion device according to claim 1, characterized in that: The ultrafiltration perfusion device (3) comprises: a tube body (303); the inner cavity of the tube body (303) comprises an ultrafiltration cavity (3031) and a perfusion cavity (3032) separated from each other; the ultrafiltration cavity inlet is connected to the liquid inlet (301); the ultrafiltration cavity outlet is connected to the perfusion cavity inlet; and the perfusion cavity outlet is connected to the liquid outlet (302).

3. The ultrafiltration perfusion device according to claim 2, characterized in that: A water filter (304) is disposed in the ultrafiltration chamber (3031), and a side wall of the ultrafiltration chamber (3031) has an ultrafiltrate outlet (305).

4. The ultrafiltration perfusion device according to claim 3, characterized in that: There are two ultrafiltrate outlets (305), one of which is close to the ultrafiltration chamber inlet and the other is close to the ultrafiltration chamber outlet.

5. The ultrafiltration perfusion device according to claim 2, characterized in that: An adsorption structure is arranged in the perfusion cavity (3032).

6. The ultrafiltration perfusion device according to claim 5, characterized in that: The adsorption structure comprises an adsorption medium (306) and a filter screen (307) arranged at the outlet of the perfusion chamber.

7. The ultrafiltration perfusion device according to claim 1, characterized in that: A power supply device and a driving device are arranged in the box body (1); the power supply device is electrically connected to the driving device, and the driving end of the driving device is connected to the blood-drawing member (2).

8. The ultrafiltration perfusion device according to claim 7, characterized in that: It also comprises a control unit, a display panel (4) and a flow rate adjustment key (5), wherein the control unit is arranged in the box body (1), the display panel (4) and the flow rate adjustment key (5) are arranged on the side wall of the box body (1), the flow rate adjustment key (5) is communicatively connected with the control unit, and the control unit is communicatively connected with the display panel (4) and the driving device.

9. The ultrafiltration perfusion device according to any one of claims 1 to 8, characterized in that: The inlet of the blood guide (2) and one end of the blood supply device, as well as the outlet of the ultrafiltration perfusion device (3) and the other end of the blood supply device, are connected via an infusion pipeline (6), and antibacterial and anticoagulant substances are provided in the infusion pipeline (6).

10. An ultrafiltration perfusion system, comprising the ultrafiltration perfusion device according to any one of claims 1 to 9, and further comprising an ECMO device, wherein the ECMO device comprises an ECMO pump and an oxygenator arranged in sequence along the direction of blood flow, characterized in that: The inlet of the blood guide (2) is connected to the rear end of the ECMO pump, and the liquid outlet (302) of the ultrafiltration perfusion device (3) is connected to the front end of the ECMO pump; Alternatively, the inlet of the blood guide (2) is connected to the rear end of the oxygenator, and the liquid outlet (302) of the ultrafiltration perfusion device (3) is connected to the front end of the ECMO pump; Alternatively, the inlet of the blood guide (2) is connected to the rear end of the oxygenator, and the liquid outlet (302) of the ultrafiltration perfusion device (3) is connected to the front end of the oxygenator.

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