Near-infrared optical imaging system for microgravity scenarios and method of use thereof

By designing a near-infrared optical imaging system for microgravity scenarios, the problem that existing systems cannot effectively analyze and evaluate the emotional and psychological state of the subject in a microgravity environment is solved, and reliable brain function imaging and evaluation in a microgravity environment is achieved.

CN119184697BActive Publication Date: 2025-04-29HUICHUANGKEYI (BEIJING) TECH CO LTD
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Patent Information

Application Number
CN202411725076.0
Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
Filing Date
2024-11-28
Publication Date
2025-04-29
Estimated Expiration
2044-11-28

AI Technical Summary

Technical Problem

The existing near-infrared optical imaging systems are mainly used for brain function analysis in conventional environments. They lack in-depth research and application in microgravity scenarios, and cannot effectively analyze and evaluate the emotional and psychological state of the subject in microgravity environment.

Method used

A near-infrared optical imaging system for microgravity scenarios is designed, including fixed components, portable signal acquisition devices, head caps and processing devices. The system fixes the signal acquisition device and the body of the subject through a bench, and fixes the cables through a wearable piece to ensure the reliable operation of the head cap and the signal acquisition device. Install a spare probe on the head cap to replace the potentially damaged probe to ensure system stability and reliability.

Benefits of technology

In a microgravity environment, the system can reliably image the subject's brain function, analyze the corresponding changes in his emotional state and brain, and provide quantitative evaluation data.

✦ Generated by Eureka AI based on patent content.

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Abstract

The embodiment of the present application provides a near-infrared optical imaging system for use in a microgravity scenario and a method of using the same. The system includes a fixed component, a portable signal acquisition device, a head cap and a processing device. The fixed component includes a stand and a wearable component. The head cap is a structure with an open top when worn, and is used to detachably install a transmitting probe and a receiving probe. The transmitting probe includes a target transmitting probe and a spare transmitting probe, and the receiving probe includes a target receiving probe and a spare receiving probe, so that the imaging range covers the target positions of the frontal lobe, temporal lobe, and occipital lobe. The transmitting probe and the receiving probe are connected to the signal acquisition device through at least a part of the cable; the signal acquisition device is used to collect the brain function imaging time series data of the subject, and send the brain function imaging time series data to the processing device for display or analysis. In this way, the emotional state of the subject in a microgravity environment and the corresponding changes in his brain can be analyzed.
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Description

Technical Field

[0001] The present application relates to the technical field of near-infrared optical imaging and detection systems, and in particular, to a near-infrared optical imaging system used in a microgravity scenario, and in particular to the arrangement and optical transmission settings of components in the near-infrared optical imaging system in a microgravity scenario. In addition, the present application also relates to a method for using the near-infrared optical imaging system. Background Art

[0002] Infrared brain functional imaging technology can use near-infrared light to detect the hemodynamic response in brain tissue to indirectly reflect the neuronal activity and its changing patterns in local brain tissue. The hemodynamic response of the brain will be affected by the environment. Existing studies have confirmed that gravitational acceleration will affect the blood supply to the brain. In hypergravity scenarios, blood will be transferred from the upper body to the lower body, resulting in reduced brain perfusion and acute ischemia and hypoxia in brain tissue. In microgravity scenarios, blood will be transferred from the lower body to the upper body, resulting in increased brain perfusion, causing benign intracranial pressure in the human body and producing idiopathic hypertension effects. These changes have important research significance and practical value in the formulation of detection indicators, setting of usage specifications, and equipment upgrades of near-infrared optical imaging systems in corresponding scenarios.

[0003] In related technologies, near-infrared optical imaging systems are often only used for scenarios such as brain function analysis in conventional environments, and lack in-depth research in unconventional usage scenarios such as microgravity scenarios and hypergravity scenarios. Summary of the invention

[0004] In order to analyze and evaluate the emotions and / or psychological state of the subject in a microgravity scene, according to the first aspect of the present application, a near-infrared optical imaging system for use in a microgravity scene is provided, the near-infrared optical imaging system comprising a fixed component, a portable signal acquisition device, a head cap and a processing device, wherein:

[0005] The fixing assembly includes a stand and a wearable piece, the stand is configured to fix the signal acquisition device on a table surface and fix the subject's body in front of the table surface, the wearable piece is configured to be worn by the subject to pass through and fix the optical fiber cable and the power supply cable from the head cap; the head cap is detachably mounted with a near-infrared light transmitting probe and a receiving probe, the transmitting probe includes a target transmitting probe and a spare transmitting probe, the receiving probe includes a target receiving probe and a spare receiving probe, so that the imaging range covers the target positions of the frontal lobe, temporal lobe, and occipital lobe brain regions, the transmitting probe is connected to the signal acquisition device via the power supply cable, so that the light source component in the transmitting probe is powered by the electric energy transmitted by the signal acquisition device; the receiving probe is connected to the signal acquisition device via the optical fiber cable, so as to transmit near-infrared light to the signal acquisition device via the optical fiber cable; the signal acquisition device is configured to acquire the brain function imaging time series data of the subject, and send the brain function imaging time series data to the processing device for display or analysis by the processing device.

[0006] According to the second aspect of the present application, a method for using a near-infrared optical imaging system in a microgravity scenario is provided. The near-infrared optical imaging system includes a fixed component, a portable signal acquisition device, a transmitting probe connected to a power supply cable, a receiving probe connected to an optical fiber cable, a head cap, and a processing device, wherein the fixed component includes a stand and a wearable device, and the method for using the signal acquisition device includes: fixing the signal acquisition device to a table through the stand, and installing the power supply cable and the optical fiber cable to the signal acquisition device so that the transmitting probe and the receiving probe are connected to the signal acquisition device; installing the target transmitting probe in the transmitting probe and the target receiving probe in the receiving probe at a set position on the head cap; fixing the subject in front of the table, and wearing the head cap on the subject's head; wearing the wearable device on the subject's upper body, and using the cable fixing component in the wearable device to pass at least part of the cable through and fix it to the subject's back; using the signal acquisition device to collect the subject's brain function imaging time series data, and sending the brain function imaging time series data to the processing device for display or analysis by the processing device.

[0007] In the near-infrared optical imaging system provided in the embodiment of the present application, the signal acquisition device is reliably fixed on the table by the stand, and the body of the subject is fixed in front of the table, and the cable connected to the head cap is fixed to the body of the subject by the wearable piece, thereby ensuring the reliable operation of the head cap and the signal acquisition device. In addition, the spare probe installed on the head cap can conveniently replace the damaged probe when the target probe is damaged when being transported to the microgravity scene. For example, the spare transmitting probe can directly replace the target transmitting probe, and the spare receiving probe can directly replace the target receiving probe, which can be easily identified. In addition, the other end of the cable connected to the spare transmitting probe and the spare receiving probe has been connected to the signal acquisition device, so it only needs to change the position of the probe for normal use. Based on the reliable operation of the head cap and the signal acquisition device, by making the imaging range cover the target positions of the frontal lobe, temporal lobe, and occipital lobe brain regions, the subject can be subjected to near-infrared brain functional imaging in a microgravity environment, and the subject's state can be evaluated based on psychology and / or cognitive neuroscience. This allows analysis of the emotional state of the subject in a microgravity environment, as well as the corresponding changes in his or her brain, thereby accumulating data and subsequently conducting a quantitative assessment of the subject's actual situation based on the data changes.

[0008] A series of simplified concepts are introduced in the summary of the invention, which will be further described in detail in the detailed description. The summary of the invention does not mean to attempt to define the key features and essential technical features of the claimed technical solution, nor does it mean to attempt to determine the scope of protection of the claimed technical solution.

[0009] The advantages and features of the present application are described in detail below in conjunction with the accompanying drawings. BRIEF DESCRIPTION OF THE DRAWINGS

[0010] The following drawings of the present application are hereby used as part of the present application for understanding the present application. The drawings show the implementation methods of the present application and their descriptions, and are used to explain the principles of the present application. In the drawings,

[0011] Figure 1 A schematic diagram showing the use of a near-infrared optical imaging system according to an exemplary embodiment of the present application is shown;

[0012] Figure 2 Shows Figure 1 Schematic diagram of the near-infrared optical imaging system in;

[0013] Figure 3 A structural diagram of a head cap and a signal acquisition device of a near-infrared optical imaging system according to an exemplary embodiment of the present application is shown;

[0014] Figure 4A partial stereoscopic view of a near-infrared optical imaging system before assembly with a head cap according to an exemplary embodiment of the present application is shown;

[0015] Figure 5 Shows Figure 4 A partial stereoscopic view of the probe and head cap of the illustrated embodiment after assembly;

[0016] Figure 6 A cross-sectional view of a cable of a near-infrared optical imaging system according to an exemplary embodiment of the present application is shown;

[0017] Figure 7A-7E The corresponding point diagrams of the transmitting probe and the receiving probe of the near-infrared optical imaging system according to an exemplary embodiment of the present application on the brain of the subject are respectively shown;

[0018] Figure 7F The figure shows the installation relationship between the hole position on the head cap and the transmitting probe and the receiving probe, wherein the installation position of the transmitting probe and the receiving probe is Figure 7A-7E corresponding;

[0019] Figure 8 A schematic flowchart showing a method for using a near-infrared optical imaging system according to an exemplary embodiment of the present application; and

[0020] Fig. 9 Shows Figure 8 The specific flow chart of step S1 is shown. DETAILED DESCRIPTION

[0021] In the following description, a large amount of details are provided so that the present application can be thoroughly understood. However, it will be appreciated by those skilled in the art that the following description only exemplarily illustrates the preferred embodiments of the present application, and the present application can be implemented without one or more such details. In addition, in order to avoid confusion with the present application, some technical features well known in the art are not described in detail.

[0022] In order to thoroughly understand the implementation of the present application, a detailed structure will be presented in the following description. Obviously, the implementation of the implementation of the present application is not limited to the specific details familiar to those skilled in the art. The preferred implementation of the present application is described in detail below, but in addition to these detailed descriptions, the present application may also have other implementations.

[0023] The present application provides a near-infrared optical imaging system. The near-infrared optical imaging system is particularly suitable for use in microgravity scenarios. A microgravity scenario refers to an environment where the apparent weight of a system is much smaller than its actual weight under the action of gravity. The near-infrared optical imaging system can be used to detect data on products related to nervous system activity and / or hemodynamic responses of subjects in different states, such as cerebral blood oxygen data, in order to understand the state of the subject based on psychology and / or cognitive neuroscience. The term "ground" used hereinafter refers to a place with a gravitational acceleration of 1 g, and the gravitational acceleration in a microgravity scenario can be less than g (g ≈ 9.80 m / s²).

[0024] Figure 1-2 An exemplary near-infrared optical imaging system according to the present application is shown. Figure 1-2 As shown, the near-infrared optical imaging system may include a fixing component, a portable signal acquisition device 200 , a head cap 300 , and a processing device 400 .

[0025] The fixing assembly may include a stand (not shown) and a wearable device 100. The stand is configured to fix the signal acquisition device 200 on a table 110. The table 110 may be any suitable support surface in a space, such as a wall, a table, or other surface on which a device can be placed. Optionally, the stand may include any component that can conveniently fix the signal acquisition device 200, such as a strap, a Velcro, or an adhesive tape.

[0026] Optionally, the stand may include components such as a ball head connection bracket, a movable arm connection bracket, etc. that can conveniently adjust the position and angle of the signal acquisition device 200. In some embodiments, the stand may also fix the subject's body in front of the stand.

[0027] Exemplarily, the stand may include armrests, and the subject may hold the armrests to ensure their own position. Exemplarily, the stand may include Velcro, straps, etc., which may fix the subject in front of the table 110. Exemplarily, the stand may include foot fixing sleeves that may fix the subject's feet. The foot fixing sleeves may, for example, be in a semicircular shape and be installed on a standing surface in the usage scenario, and the subject's feet may be inserted into the foot fixing sleeves. The wearable item 100 may be worn by the subject to pass through and fix the optical fiber cables and power supply cables from the head cap 300. The wearable item 100 may include but is not limited to vests, waistcoats, jackets, belts, etc., and may also include structures that are directly attached to the subject's body by Velcro, or may include bracelets, etc. In this way, it is possible to avoid cables from floating around and getting entangled or even damaged in a microgravity scenario. See. Figure 1 , multiple cables can be bundled and wrapped in a tube or strip shape, leaving only a small part of the cables exposed, thus minimizing their fluttering or entanglement.

[0028] The head cap 300 itself can be elastic and adjustable, so as to be suitable for different subjects. Exemplarily, the head cap 300 can be a ring-shaped structure with an open top when worn. This not only allows for a larger adjustable range, but also can play a positioning role, and the inspection results are more accurate. In a microgravity environment, the subject's head will swell, and the ring-shaped structure is more comfortable than the fully wrapped structure, and the claustrophobic feeling it brings to the user is also weaker. Exemplarily, the head cap 300 can cover the entire brain of the subject when worn.

[0029] The head cap 300 is detachably mounted with a transmitting probe and a receiving probe. The transmitting probe may include a target transmitting probe and a spare transmitting probe. The receiving probe may include a target receiving probe and a spare receiving probe. The positions for installing the target transmitting probe and the target receiving probe on the head cap 300 are configured so that the imaging range covers the target positions of the frontal lobe, temporal lobe, and occipital lobe. Exemplarily, the target transmitting probe and the target receiving probe are mainly targeted at the brain areas related to emotion regulation, so as to focus on detecting the changes in the emotions of the subject in a microgravity environment or a claustrophobic microgravity environment. All target transmitting probes, target receiving probes, spare transmitting probes, and spare receiving probes can be installed on the head cap 300. Therefore, the present application does not expect to limit the shape of the head cap 300 itself, as long as the transmitting probe and the receiving probe can cover the target positions of each brain area after being installed thereon, the transmitting probe is connected to the signal acquisition device through the power supply cable, and the light source assembly in the transmitting probe is powered by the electric energy transmitted by the signal acquisition device; the receiving probe is connected to the signal acquisition device through the optical fiber cable, so as to transmit near-infrared light to the signal acquisition device through the optical fiber cable. For the sake of brevity, the target transmitting probe and the target receiving probe are collectively referred to as target probes, and the spare transmitting probe and the spare receiving probe are collectively referred to as spare probes.

[0030] Since the near-infrared optical imaging system needs to be sent into microgravity and is subject to the influence of many factors such as overload, vibration, weightlessness and radiation during use, there is a certain risk of damage to the probe and cable. The present application reduces the dependence on the maintenance of the probe and cable by providing a spare probe that can be easily activated at any time. In order to avoid entanglement, collision and damage of too many target probes and spare probes and the connected cables, the target probe and spare probe can be separated from the head cap 300 and can also be protected by a packaging box during delivery to the microgravity environment. Installing the target probe and spare probe to the head cap 300 in the microgravity environment can prevent the cables from being entangled and the probes from colliding with each other in a weightless state. And this makes wiring more convenient. Of course, the present application does not exclude an embodiment in which the target probe and spare probe are installed to the head cap 300 in advance.

[0031] The signal acquisition device 200 can be used to acquire the brain function imaging time series data of the subject, and send the brain function imaging time series data to the processing device 400 for display or analysis by the processing device 400. The processing device 400 can include any suitable computer device such as a desktop computer, a server, a laptop, a tablet computer, a mobile phone, etc.

[0032] In a preferred embodiment, the processing device 400 can be a computer already in the microgravity scene with the acquisition software installed. In one embodiment, the signal acquisition device 200 can be used only to receive the electrical signal from the processing device 400, so that the target transmitting probe emits near-infrared light, and converts the near-infrared light signal detected by the target receiving probe into an electrical signal and transmits it to the processing device 400. In other embodiments, the signal acquisition device 200 can also include a processor and other components capable of performing computing functions, and communicate with the processing device 400 to control the light-emitting element of the near-infrared light so that the target transmitting probe emits near-infrared light, and converts the near-infrared light signal detected by the target receiving probe into an electrical signal and sends it to the processing device 400 after processing. In short, due to the relatively strong computing power of the processing device 400, the processing device 400 can be made to undertake all or most of the computing functions, thereby simplifying the structure of the signal acquisition device 200 to ensure that it is light enough and reliable enough. In some embodiments, the signal acquisition device 200 is also reinforced to resist overload and radiation to ensure that it can still be used normally after experiencing a transmission environment that may be overloaded and highly radiated and reaching a microgravity environment.

[0033] In the near-infrared optical imaging system provided in the embodiment of the present application, the signal acquisition device 200 is reliably fixed on the table by the table, and the body of the subject is fixed in front of the table, and the cable connected to the head cap 300 is fixed to the body of the subject by the wearable piece, thereby ensuring the reliable operation of the head cap 300 and the signal acquisition device 200. In addition, the spare probe installed on the head cap 300 can conveniently replace the damaged probe when the target probe is damaged when being transported to the microgravity scene. For example, the spare transmitting probe can directly replace the target transmitting probe, and the spare receiving probe can directly replace the target receiving probe, which can be easily identified. In addition, the other end of the cable connected to the spare transmitting probe and the spare receiving probe is already connected to the signal acquisition device 200, so it only needs to change the position of the probe for normal use. Based on the reliable operation of the head cap 300 and the signal acquisition device 200, by making the imaging range cover the target position within the frontal lobe, temporal lobe, and occipital lobe, the subject can be subjected to a near-infrared brain function examination in a microgravity environment, and the subject's state can be evaluated based on psychology and / or cognitive neuroscience. This allows analysis of the emotional state of the subject in a microgravity environment, as well as the corresponding changes in his or her brain, thereby accumulating data and subsequently conducting a quantitative assessment of the subject's actual situation based on the data changes.

[0034] Continue to refer Figure 1 to Figure 2 , illustratively, the near-infrared optical imaging system may further include a paradigm material display device 500. The paradigm material display device 500 is set to a suitable position above and in front of the subject with an adjustable bracket 600 to display paradigm materials matching the paradigm to the subject during the signal acquisition process. The adjustable bracket 600 includes but is not limited to a joint movable arm bracket, a scissor adjustment bracket, etc. Thus, the subject can adjust the distance between the paradigm material display device 500 and the eyes to obtain the best viewing angle and distance. Paradigm materials may include materials such as pictures and videos that provide external stimuli. The paradigm material display device 500 may include but is not limited to LCD screens, tablet computers, slides, virtual reality (VR) devices, augmented reality (AR) devices, and other devices that can display paradigm materials to the subject.

[0035] like Figure 1 and Figure 2 In the microgravity environment shown, taking the paradigm material display device 500 as a tablet computer as an example, the preferred arrangement is that the paradigm material display device 500 and the computer as the processing device 400 can be respectively arranged on the left and right sides in front of the subject, so that the subject can easily observe the display screens of the two at the same time, which is convenient for operating the two. Of course, in other embodiments, the two can also be fixed up and down or all placed on the left or right side.

[0036] In some embodiments, the paradigm material display device 500 may only include a display screen, which can display the paradigm material to the subject, but cannot directly receive the user's operation. In this embodiment, the subject can perform a marking operation when the paradigm material display device 500 displays the paradigm material through a marking device such as a mouse, keyboard, joystick, or handle connected to the signal acquisition device 200. The marking operation includes but is not limited to clicking on a target pattern, drawing a circle to encircle the target pattern, etc. The signal acquisition device 200 can process the marking data generated in response to the marking operation.

[0037] In some possible embodiments, the paradigm material display device 500 can be communicatively connected to the signal acquisition device 200. The paradigm material display device 500 can also be used to respond to the marking operation during the paradigm material display process, send the marking data to the signal acquisition device 200, so that the signal acquisition device 200 can process the marking data, or send the marking data and the collected brain function imaging time series data to the processing device 400 for processing. In these embodiments, the paradigm material display device 500 can include a touch screen, etc., which can directly receive the operation of the subject, thereby making it more convenient to perform the marking operation.

[0038] Exemplarily, the transmitting probe is used to transmit near-infrared light of at least one preset wavelength to the head of the subject, and the receiving probe is used to receive the near-infrared light emitted from the head of the subject. The signal acquisition device 200 may include a near-infrared light transmitting element and a near-infrared light receiving element, the transmitting element includes but is not limited to a laser, a light emitting diode, etc., the receiving element may include a photodiode, a silicon photocell, etc., and may also be matched with a filter that matches the wavelength of the near-infrared light emitted by the transmitting element. Optionally, the signal acquisition device 200 may also be provided with a processor chip such as an MCU, a CPU, an MPU, a RISC processor, an FPGA, a DSP, etc. and its peripheral circuits, digital and analog chips, and circuits of peripheral components, memories, etc. The signal acquisition device 200 may be connected to the aforementioned transmitting probe and receiving probe via a cable. In this case, the cable may include an optical fiber. The transmitting element cooperates with an optical element to collimate the near-infrared light and input it into the optical fiber, and the transmitting probe optically adjusts the near-infrared light of the outgoing optical fiber. The receiving probe can collect the near-infrared light emitted from the head of the subject and transmit it to the receiving element via the optical fiber.

[0039] In other embodiments, the signal acquisition device 200 may not include a transmitting element and / or a receiving element. The transmitting element and the receiving element may be respectively arranged on a transmitting probe and a receiving probe. In this case, the cable may be used to transmit power between the transmitting probe and the signal acquisition device 200, and / or between the receiving probe and the signal acquisition device 200.

[0040] In some embodiments, a spare transmitting probe and a spare receiving probe can be installed in the corresponding area of ​​the occipital part of the head cap 300. The spare probe installed in this way can maintain a certain distance from the target probe, and there are fewer target probes installed in the occipital part, so the subject is not easily affected by the spare probe during the process of adjusting the target probe. In other embodiments, the spare probe is installed adjacent to and corresponding to at least part of the target transmitting probe and / or at least part of the target receiving probe, and is used to replace the faulty probe located in the same cerebral hemisphere. The spare probe can also correspond to different cerebral hemispheres, and when the target probe is damaged, it can be replaced and enabled accordingly. The cables of the target probe and the spare probe of the ipsilateral cerebral hemisphere can be adjacent or can be tied at a certain distance from the probe. When replacing, the cables of the spare probe and the target probe corresponding to the ipsilateral cerebral hemisphere are not easy to be entangled with each other after replacement, and the cable distribution is more reasonable.

[0041] like Figure 3 As shown, exemplarily, the cable has a first end connected to the transmitting probe or the receiving probe, and the cable can be constrained into a bundle by a cable harness assembly. The cable harness assembly can bundle more and scattered cables into a bundle, which is more tidy, and can also protect each cable from entanglement, pulling and scratching. The cable harness assembly can be made of nylon, PVC, etc., which can have a high tensile strength. The near-infrared optical imaging system can also include a first tensile member. The first tensile member can be connected between the head cap 300 and the first position of the cable harness assembly. During the process of wearing the head cap 300 or before wearing the head cap 300, there may be a situation where the head cap 300 is hooked when the subject pulls the cable harness assembly. The length of the portion of the cable between the first position and the first end can be greater than the length of the first tensile member. In this way, the first tensile member can be straightened first to prevent the force during pulling from directly acting on the cable, thereby protecting the cable. The first tensile member can include nylon rope, steel wire, chain, etc.

[0042] Exemplarily, the cable may have a second end connected to the signal acquisition device 200. The near-infrared optical imaging system may further include a second tensile member. The second tensile member may be connected between the signal acquisition device 200 and the second position of the cable assembly. The length of the portion of the cable between the second position and the second end may be greater than the length of the second tensile member. When the subject pulls the cable assembly and the signal acquisition device 200 is fixed to the table, the second tensile member can prevent a large external force from acting on the cable to protect the cable. The second tensile member may also include a nylon rope, a steel wire, a chain, etc.

[0043] Exemplarily, the wearable device 100 may include a cable fixing assembly that passes at least part of the cable through and fixes it to the back of the subject. In this way, the subject does not need to worry about the cable during the test. The cable can extend relatively straight from the head cap 300 to the wearable device 100 and be fixed on the subject without affecting the subject's movements. Moreover, it can prevent the cable from floating in a microgravity environment and affecting the normal use of other equipment, or from getting entangled in the subject's body and causing accidents.

[0044] As described above, the target transmitting probe and the target receiving probe are mainly targeted at brain areas related to emotion regulation, and there is an upper limit to the installation density of the probes on the head cap 300. Therefore, for the lobes with more detection points, the area covered by the head cap 300 is also increased accordingly, so that more probes can be securely installed. Brain areas with fewer points to be detected, such as the brain areas corresponding to the occipital lobe, can be installed with fewer probes, so the area covered by the head cap 300 can be reduced to reduce the sense of restraint. Exemplarily, the area of ​​the first brain area of ​​the frontal lobe of the subject covered by the head cap 300 can be larger than the area of ​​the second brain area of ​​the occipital lobe of the subject covered by the head cap 300. Exemplarily, the area of ​​the third brain area of ​​the temporal lobe of the subject covered by the head cap 300 can be larger than the area of ​​the second brain area. Optionally, in other embodiments, the area of ​​the first brain area can be equal to or less than the area of ​​the second brain area. Optionally, in other embodiments, the area of ​​the third brain area can also be less than or equal to the area of ​​the second brain area.

[0045] Exemplarily, the transmitting probe and the receiving probe are respectively fixedly connected to their respective upper buckles, and the transmitting probe and the receiving probe are detachably connected to the lower buckles of the corresponding mounting positions on the head cap 300 through their respective upper buckles. Figure 4 and Figure 5 The connection process of the probe 700 with the upper buckle 710 and the lower buckle 720 is shown. The probe 700 can be any one of a transmitting probe and a receiving probe. As shown in the figure, the probe 700 can be first fixed to the upper buckle 710, and then the upper buckle 710 can be installed on the lower buckle 720. Exemplarily, the probe 700 can be pre-bonded to the upper buckle 710. The lower buckle 720 can be pre-fixed on the head cap 300. In the microgravity scenario, it is only necessary to install the upper buckle 710 to the lower buckle 720 to complete the connection between the probe 700 and the head cap 300. In this way, when the near-infrared optical imaging system is sent to the microgravity experimental environment, the probe and the head cap 300 can be placed separately, so as to avoid damage to the probe and the head cap 300 due to factors such as overload when arriving at the microgravity experimental environment. The buckle structure is a relatively mature design, and the detachable structure can facilitate the replacement of the target probe with a spare probe.

[0046] Exemplarily, the head cap 300 may be provided with first marks corresponding to each installation position, and the upper buckles corresponding to the transmitting probe and the receiving probe may be provided with second marks. For each of the transmitting probe and the receiving probe, the second mark on the corresponding upper buckle may be associated with the corresponding first mark on the head cap 300. The first mark may be provided on the head cap 300 by means of embroidery, printing, etc., or may be engraved or laser marked on the lower buckle of the head cap 300. The second mark of the upper buckle may also be engraved, printed or laser marked thereon.

[0047] The first mark on the existing head cap 300, and the second marks on the transmitting probe and the receiving probe can be set as follows: the first mark of the installation position of the transmitting probe on the head cap 300 and the second mark on the transmitting probe are correspondingly marked as S1, S2, S3..., the transmitting probe marked with S1 is installed to the installation position marked with S1, the transmitting probe marked with S2 is installed to the installation position marked with S2, and so on. The first mark of the installation position of the receiving probe on the head cap 300 and the second mark on the receiving probe are correspondingly marked as D1, D2, D3..., and the installation method is the same as the installation of S1 and S2.

[0048] To simplify the installation process, in the present application, all the first identification marks on the head cap 300 for identifying the transmitting probe and the receiving probe can be numbered consecutively, such as 1, 2, 3... However, the identification marks S1, S2, S3... can still be used on the transmitting probe; the identification marks D1, D2, D3... can still be used on the receiving probe. During the installation process, the probe labeled S1 can be inserted into hole 1 on the head cap 300, and the probe labeled S2 can be inserted into hole 2 on the head cap 300, and so on. In some embodiments not shown, the identification marks on the transmitting probe and the receiving probe can also be set to pure numbers, and it is only necessary to install the numbers on the probes corresponding to the numbers of the installation positions.

[0049] Figure 7A-7E The regions of the subject's brain corresponding to the transmitting probe and the receiving probe are shown. Figure 7F FIG. 1 shows the deployed position diagram of the transmitting probe and the receiving probe on the head cap according to an exemplary embodiment of the present application. The S logo corresponds to the transmitting probe, and the D logo corresponds to the receiving probe. Figure 7F As shown in the figure, each circle represents a mounting position on the head cap for mounting the target probe, that is, the "hole position" marked by the red words in the figure. Among them, the purple circle represents the mounting position of the target transmitting probe; the blue circle represents the mounting position of the target receiving probe. Figure 7FA total of 40 holes from O1 to O40 are included, including 24 target transmitting probe mounting positions and 16 target receiving probe mounting positions. In the illustrated embodiment, mounting positions O1 and O2 are connected to target receiving probes D1 and D2, respectively. Mounting positions O3 to O8 are connected to target transmitting probes S1 to S6, respectively. Mounting positions O9 to O12 are connected to target receiving probes D3 to D6, respectively. Mounting positions O13 to O18 are connected to target transmitting probes S7 to S12, respectively. Mounting positions O19 to O22 are connected to target receiving probes D7 to D10, respectively. Mounting positions O23 to O28 are connected to target transmitting probes S13 to S18, respectively. Mounting positions O29 to O32 are connected to target receiving probes D11 to D14, respectively. Mounting positions O33 to O36 are connected to target transmitting probes S19 to S22, respectively. Mounting positions O37 to O38 are connected to target receiving probes D15 to D16, respectively. The mounting positions O39 to O40 are connected to the target launch probes S23 to S24 respectively.

[0050] The number of spare probe installation positions can be set as needed. For example, installation positions O41 to O50 can be additionally set as spare probe installation positions.

[0051] Optionally, in other embodiments not shown, a part of the installation positions with consecutive numbers can also be used as the target transmitting probe, and another part of the installation positions with consecutive numbers can be used as the target receiving probe installation position. Still taking the 40 installation positions including O1 to O40 as an example, the installation positions O1 to O24 can be sequentially connected to the target transmitting probes S1 to S24, and the installation positions O25 to O40 can be sequentially connected to the target receiving probes D1 to D16. In this case, for example, the installation positions O41 to O50 can be used as spare probe installation positions. Optionally, in other embodiments not shown, a part of the installation positions with consecutive numbers can also be used as the installation positions of all transmitting probes (including the target transmitting probe and the spare transmitting probe), and another part of the installation positions with consecutive numbers can be used as the installation positions of all receiving probes (including the target receiving probe and the spare receiving probe). Exemplarily, the installation positions O1 to O29 can be used to connect the transmitting probe marked with S. Exemplarily, the installation positions O1 to O24 can be connected to the target transmitting probe, and the installation positions O25 to O29 can be connected to the spare transmitting probe. The mounting positions O30 to O45 can be used to connect the target receiving probe, and the mounting positions O46 to O50 can be used to connect the spare receiving probe. In short, those skilled in the art can assign corresponding digital numbers to each mounting position as needed, and set the corresponding relationship between all probes and digital numbers as needed.

[0052] The inventors are aware and understand that one of the main reasons for the breakage and damage of optical fibers in optical fiber cables is that the optical fibers are subjected to pulling forces along their longitudinal direction. The optical fibers in currently common optical fiber cables include a guide fiber core and a cladding coated outside the guide fiber core. Light is transmitted in the guide fiber core in a total reflection manner, and the cladding can prevent the guide fiber core from breaking, and form an interface with a large refractive index difference with the guide fiber core. An optical fiber cable may include one or more optical fibers. A protective layer is usually provided on the outside of the optical fiber, which is used to prevent the optical fiber from being damaged or broken due to wear or scratching during use. The inventors have found that in existing optical fiber cables, the optical fiber is usually tightly fitted with the protective layer, or the gap between the optical fiber and the protective layer is filled with fillers. Although this ensures the strength of the optical fiber cable, it will also cause a large pressure or friction coefficient between the optical fiber and the protective layer, and further make the maximum static friction between the optical fiber and the protective layer very large. Under the action of static friction, the optical fiber and the protective layer are always stationary and move synchronously with each other. Especially in a microgravity environment, unexpected drifting of the subject's body may generate a large force on the cable, and the external force acting on the protective layer will be directly transmitted to the inner optical fiber, causing the optical fiber to easily break and be damaged.

[0053] like Figure 6As shown, the optical fiber cable 1 used in the present application may include an optical fiber 11, a fabric layer 12, and a jacket layer 13. The fabric layer 12 is sleeved on the optical fiber 11 as a protective layer on the outside of the optical fiber 11. In at least the middle section of the optical fiber cable 1, the fabric layer 12 is slidable relative to the optical fiber 11 at least along the longitudinal direction of the optical fiber 11. The longitudinal direction can be considered to be consistent with the length direction of the optical fiber 11. It should be noted that in actual use, the optical fiber cable 1 is usually curved, so the longitudinal direction may be different for different sections of the optical fiber 11. For example, for a vertical section of the optical fiber 11, the longitudinal direction of this section of the optical fiber 11 is the vertical direction; and for a horizontal section of the optical fiber 11, the longitudinal direction is the horizontal direction. The aforementioned "slidable" means that there is a small friction coefficient between the fabric layer 12 and the optical fiber 11, and there is no other mutual binding force between the two except the friction force. Exemplarily, the method of reducing the friction between the fabric layer 12 and the optical fiber 11 includes but is not limited to: using a lubricant, reducing the friction coefficient of the outer surface of the optical fiber 11 and / or the inner surface of the fabric layer 12, etc. When the optical fiber cable 1 is subjected to an external force, the fabric layer 12 can slide relative to the optical fiber 11. The benefit brought by this is that when the middle section of the optical fiber cable 1 is suddenly subjected to a component force in the longitudinal direction, for example, the user suddenly pulls the middle section of the optical fiber cable 1, or the middle section of the optical fiber cable 1 suddenly falls, since the fabric layer 12 and the optical fiber 11 can slide at least in the longitudinal direction, the fabric layer 12 and the jacket layer 13 can play a buffering role, so that the acceleration and / or moving distance of the optical fiber 11 is smaller than that of the fabric layer 12 and the jacket layer 13, thereby protecting the optical fiber 11 and preventing the above external force from being directly transmitted to the optical fiber 11.

[0054] The present application sets the fabric layer 12 to have an elongation in the longitudinal direction lower than the first threshold value. The elongation can be considered as the degree to which an object can be stretched after being subjected to a tensile force. When subjected to the same tensile force and the same size of the material, the lower the elongation of the material itself, the shorter the length of stretchability. In this way, during or at least one period of time after the movement of the optical fiber cable 1, the fabric layer 12 is in a tensioned state, and the optical fiber 11 is preferably in a relaxed state in the fabric layer 12, thereby avoiding the optical fiber 11 from being subjected to force. The inventor has found that when moving the optical fiber cable 1, the user usually needs to apply pressure to hold the optical fiber cable 1 to increase the friction between the hand and the outer surface of the optical fiber cable 1, thereby avoiding the optical fiber cable 1 from sliding in the hand. When the pressure applied by the user is large enough, the friction between the fabric layer 12 and the optical fiber 11 will also increase, and the optical fiber 11 will also move with the fabric layer 12. Of course, being able to move the inner layer of the optical fiber 11 is also desired by the user. Even in the case described above, after the fabric layer 12 slides relative to the optical fiber 11, it is ultimately expected that the optical fiber 11 can be moved. During or after the optical fiber 11 is moved, the tension applied by the user in the longitudinal direction is expected to be borne by the fabric layer 12 or by the fabric layer 12 and the jacket layer 13 together. It is best for the optical fiber 11 to be moved only by the fabric layer 12 without directly bearing the tension applied by the user.

[0055] The fabric layer 12 is slidable at least along the longitudinal direction relative to the optical fiber 11, and the elongation of the fabric layer 12 along the longitudinal direction is lower than the first threshold value, which complement each other. Specifically, the smaller the first threshold value is, the better, and it is best that the fabric layer 12 cannot be stretched under the action of external force. Even if the fabric layer 12 can be stretched under the action of external force, it is also expected that the tension acting on the optical fiber 11 is reduced when the fabric layer 12 is straightened to avoid damaging the optical fiber 11. On the other hand, when the tension along the longitudinal direction is transmitted from the outside to the inside of the optical fiber cable 1, since the fabric layer 12 is slidable at least along the longitudinal direction of the optical fiber 11 relative to the optical fiber 11, the tension acting on the fabric layer 12 may not be completely applied to the optical fiber 11 due to the slippage of the optical fiber 11, thereby reducing the possibility of the optical fiber 11 being stretched to a certain extent and reducing the risk of the optical fiber 11 breaking.

[0056] Since both ends of the optical fiber cable 1 are fixed on the signal acquisition device 200 and the probe assembled on the head cap 300, when the head cap 300 is worn on the head of the subject, there is usually a certain distance between it and the signal acquisition device 200. Therefore, during use, the middle section of the optical fiber cable 1 may be held by the user and caught by surrounding objects. Therefore, the fabric layer 12 can be slidable along the longitudinal direction relative to the optical fiber 11 only in the middle section of the optical fiber cable 1. Of course, the present application does not exclude the embodiment in which the fabric layer 12 is slidable along the longitudinal direction relative to the optical fiber 11 in the entire optical fiber cable 1. As described above, the direction in which the optical fiber cable 1 is subjected to force may not be limited to the longitudinal direction. Therefore, in some embodiments, the fabric layer 12 is also slidable along other directions relative to the optical fiber 11. Exemplarily, the optical fiber cable 1 may also be partially twisted during use, and the slidable fabric layer 12 relative to the optical fiber 11 along the circumferential direction can also provide a buffer when the optical fiber cable 1 is twisted, avoiding the torsional force and / or the acceleration of the torsional force from acting directly on the optical fiber 11.

[0057] The outer jacket 13 of the optical fiber cable 1 can be sleeved on the fabric layer 12 as a protective layer outside the fabric layer 12. The outer jacket 13 is opaque and flexible. The wear resistance and snag resistance of the fabric layer 12 may be relatively poor. The outer jacket 13 can protect the fabric layer 12 and extend its service life. The outer jacket 13 can be made of a material with high wear resistance, such as PVC or nylon. Moreover, PVC and nylon materials are also flexible and can be bent freely, even with a large curvature to meet on-site needs, and are opaque to avoid leakage during near-infrared light transmission or interference from external light.

[0058] Since the signal acquisition device in the related scheme is used in a conventional gravity environment, in order to facilitate the subject to move within a certain range, the signal acquisition device can be placed in a backpack, and the signal acquisition device can communicate wirelessly with the communication module connected to the processing device 400. As a result, the processing device 400 (such as a computer) can be used within a certain range away from the signal acquisition device after connecting the communication module. However, in a microgravity experimental environment, when transmitting brain function imaging time series data to the processing device 400, due to the large amount of data, the interference that may be received is also large. And a longer communication distance requires a stronger signal, which may interfere with the electronic equipment in the microgravity experimental environment. Exemplarily, the processing device 400 can be connected to the signal acquisition device 200 by wire through the communication module, and the communication module can be placed in the signal acquisition device 200. In the signal acquisition device 200, the circuit of the signal acquisition device 200 communicates with the communication module at a very close distance, and then the communication module transmits the data to the processing device 400 by wire, and there will be no change in compatibility after modifying the circuit design, and its reliability can be retained. The shorter wireless communication transmission distance between the internal circuit of the signal acquisition device and the communication module, as well as the wired transmission between the communication module and the processing device 400 can also reduce the negative impact of signal interference.

[0059] Exemplarily, the near-infrared optical imaging system may also include a phantom device for testing the performance of the optical transmission path in the near-infrared optical imaging system. The phantom device is portable and includes a housing, an optical attenuation component, and a storage module. The housing is provided with a communication interface and a plurality of probe interfaces arranged in pairs. The probe interfaces arranged in pairs are used to plug in the paired transmitting probes and receiving probes in the signal acquisition device 200. These paired probe interfaces correspond one to one with the target probe positions on the head cap 300. The optical attenuation component is arranged in the housing and includes a stacked filter layer and an attenuation body. The optical attenuation component is arranged corresponding to the light-emitting end of the transmitting probe and the light-receiving end of the receiving probe, so that the near-infrared light emitted by the transmitting probe is transmitted to the receiving probe via the filter layer and the attenuation body in turn.

[0060] The light attenuation component is used to make the near-infrared light on the optical path between the paired transmitting probe and the receiving probe attenuate with the calibrated attenuation parameter. Since the human head has a large attenuation of near-infrared light, the sensitivity of the receiving element is set to be relatively high. If the received near-infrared light comes directly from the transmitting element or is not sufficiently attenuated, it may cause the measurement data to exceed the range or even damage the receiving element. The light attenuation component can simulate the light intensity of the near-infrared light that actually irradiates the head of the subject when it is emitted from the head to a certain extent, so that the phantom can be used to detect whether the probe is intact. In some embodiments, the light attenuation component may not be completely consistent with the attenuation of the human body, and it is only necessary to make the detected near-infrared light intensity within the detection range and the attenuation stable. The storage module can be arranged in the housing of the phantom device, the storage module stores the calibrated attenuation parameter, and the communication interface is used to output the calibrated attenuation parameter. The signal acquisition device 200 can also obtain the calibrated attenuation parameter via the communication interface of the phantom device. Among them, the difference between the calibrated attenuation parameter and the reference attenuation parameter is within a preset range. The signal acquisition device 200 can emit near-infrared light to the phantom device, and determine the detected attenuation parameter based on the received near-infrared light signal. The signal acquisition device 200 can also compare the detected attenuation parameter with the calibrated attenuation parameter. When the difference between the two is large and exceeds the preset range, it can be considered that one or both of the corresponding transmitting probe and the corresponding receiving probe have failed. The structure of the phantom is relatively strong and simple. It is not easy to fail under the influence of overload and vibration, and can be used to detect whether the probe is damaged.

[0061] In a specific embodiment, the phantom may include multiple pairs of probe interfaces, and for each pair of probe interfaces, after obtaining the incident light, the test attenuation light intensity data of the outgoing light is obtained. The phantom may be tested on the ground before being sent into the microgravity experimental environment to determine the calibration attenuation parameters. The light attenuation calibration results corresponding to each pair of probe interfaces may be determined based on the calibration attenuation parameters and the test attenuation parameters corresponding to each pair of probe interfaces. When using the phantom, it may be determined whether the probe is damaged according to the light attenuation calibration results, and in the case where the probe is damaged, the brain function imaging time series data of the subject is collected using the spare probe that has passed the detection. In this way, before collecting the brain function imaging time series data of the subject, the phantom is used to detect whether the near-infrared optical imaging system can work normally, and the brain function imaging time series data of the subject is collected again if it can work normally, so as to ensure that the collected brain function imaging time series data of the subject is accurate, and avoid the deviation of the brain function analysis results caused by the imaging equipment.

[0062] The present application also provides a method for using the near-infrared optical imaging system according to various embodiments of the present application. Figure 8 As shown, the method of use includes:

[0063] Step S1: fix the signal acquisition device 200 to the table surface through the stand, and install the power supply cable and the optical fiber cable to the signal acquisition device 200 so that the transmitting probe and the receiving probe are connected to the signal acquisition device 200.

[0064] Step S2: Install the target transmitting probe in the transmitting probe and the target receiving probe in the receiving probe at the set positions on the head cap 300.

[0065] Step S3: Fix the subject in front of the table and wear the head cap 300 on the subject's head.

[0066] Step S4: Wear the wearable device 100 on the upper body of the subject, and use the cable fixing component in the wearable device 100 to pass at least part of the cable through and fix it to the back of the subject.

[0067] Step S5: using the signal acquisition device 200 to acquire the brain function imaging time series data of the subject, and sending the brain function imaging time series data to the processing device 400 for display or analysis by the processing device 400.

[0068] In actual use, step S4 can also be executed at any time before steps S1, S2 and S3. In short, except for step S5 which is executed last, the other steps may not be executed strictly in order. For example, the probe is first installed on the head cap 300 only for the convenience of single-person operation. In actual use, it is not ruled out that the head cap 300 is worn first, and then the probe is installed on the head cap 300 by other persons other than the subject.

[0069] For example, Fig. 9 As shown, using the signal acquisition device 200 to collect the brain function imaging time series data of the subject may include the following:

[0070] Step S11, obtaining a calibrated attenuation parameter of a phantom device, wherein the phantom device is used to simulate the attenuation of incident light in the subject;

[0071] Step S12, obtaining the initial light intensity detection result of the outgoing light emitted from the phantom device after the incident light enters the detection environment of the phantom device;

[0072] Step S13, determining a standard light intensity detection result of the optical transmission path in the near-infrared optical imaging system under a standard phantom detection environment based on the initial light intensity detection result and the calibrated attenuation parameter of the phantom device;

[0073] Step S14, comparing the standard light intensity detection result with the standard light intensity range to determine the detection result of the light transmission path in the near-infrared optical imaging system;

[0074] Step S15 , when the detection result of the light transmission path in the near-infrared optical imaging system is that the detection is passed, the signal acquisition device 200 is used to acquire the brain function imaging time series data of the subject.

[0075] It should be noted that Fig. 9 All steps shown can be found in Figure 8 The step S2 shown is performed before, so as to determine whether there is a faulty probe in the transmitting probe and the receiving probe.

[0076] In the description of the present application, it should be understood that the orientation or positional relationship indicated by directional words such as "front", "back", "up", "down", "left", "right", "lateral", "vertical", "vertical", "horizontal", "top", "bottom", etc. is usually based on the orientation or positional relationship shown in the drawings, and is only for the convenience of describing the present application and simplifying the description. Unless otherwise specified, these directional words do not indicate or imply that the device or element referred to must have a specific orientation or be constructed and operated in a specific orientation, and therefore cannot be understood as limiting the scope of protection of the present invention; the directional words "inside" and "outside" refer to the inside and outside relative to the outline of each component itself.

[0077] For ease of description, regional relative terms such as "above", "above", "on the upper surface", "above", etc. may be used here to describe the regional positional relationship between one or more components or features shown in the figure and other components or features. It should be understood that regional relative terms include not only the orientation of the components as described in the figure, but also different orientations in use or operation. For example, if the components in the accompanying drawings are inverted as a whole, the components "above other components or features" or "above other components or features" will include the situation where the components are "below other components or structures" or "below other components or structures". Therefore, the exemplary term "above" may include both "above" and "below". In addition, these components or features may also be positioned at other different angles (e.g., rotated 90 degrees or other angles), and this article is intended to include all of these situations.

[0078] It should be noted that the terms used herein are only for describing specific embodiments and are not intended to limit the exemplary embodiments according to the present application. As used herein, unless the context clearly indicates otherwise, the singular form is also intended to include the plural form. In addition, it should be understood that when the terms "comprise" and / or "include" are used in this specification, it indicates the presence of features, steps, operations, parts, components and / or combinations thereof.

[0079] It should be noted that the terms "first", "second", etc. in the specification and claims of the present application and the above-mentioned drawings are used to distinguish similar subjects, and are not necessarily used to describe a specific order or sequence. It should be understood that the numbers used in this way can be interchanged where appropriate, so that the embodiments of the present application described herein can be implemented in an order other than those illustrated or described herein.

[0080] The present application has been described through the above-mentioned embodiments, but it should be understood that the above-mentioned embodiments are only for the purpose of example and description, and are not intended to limit the present application to the scope of the described embodiments. In addition, it can be understood by those skilled in the art that the present application is not limited to the above-mentioned embodiments, and more variations and modifications can be made according to the teachings of the present application, and these variations and modifications all fall within the scope of the protection claimed by the present invention. The protection scope of the present invention is defined by the attached claims and their equivalent scope.

Claims

1. A near-infrared optical imaging system for use in microgravity scenarios, characterized in that: The near-infrared optical imaging system includes a fixed component, a portable signal acquisition device, a head cap and a processing device, wherein: The signal acquisition device is reinforced to resist overload; The fixing assembly includes a stand and a wearable piece, the stand is configured to fix the signal acquisition device on the stand and fix the subject's body in front of the stand, the wearable piece is configured to be worn by the subject to thread and fix the optical fiber cable and the power supply cable from the head cap, and the wearable piece includes a cable fixing assembly for threading and fixing at least part of the cables to the back of the subject; The head cap is detachably mounted with a near-infrared light transmitting probe and receiving probe, the transmitting probe includes a target transmitting probe and a spare transmitting probe, and the receiving probe includes a target receiving probe and a spare receiving probe, so that the imaging range covers the target positions of the frontal lobe, temporal lobe, and occipital lobe brain regions. The transmitting probe is connected to the signal acquisition device via the power supply cable, so that the light source assembly in the transmitting probe is powered by the electric energy transmitted by the signal acquisition device; the receiving probe is connected to the signal acquisition device via the optical fiber cable, so that near-infrared light is transmitted to the signal acquisition device via the optical fiber cable, and the cables of the target probe and the spare probe of the ipsilateral cerebral hemisphere are tied tightly at a certain distance from the probes; The signal acquisition device is used to acquire the brain function imaging time series data of the subject, and send the brain function imaging time series data to the processing device for display or analysis by the processing device.

2. The near-infrared optical imaging system according to claim 1, characterized in that: The near-infrared optical imaging system also includes a paradigm material display device, which is set to a suitable position above and in front of the subject with an adjustable bracket to display paradigm materials matching the selected paradigm to the subject during signal acquisition.

3. The near-infrared optical imaging system according to claim 2, characterized in that: The paradigm material display device is communicatively connected to the signal acquisition device, and the paradigm material display device is also used for: In response to the marking operation during the presentation of the paradigm material, the marking data is sent to the signal acquisition device so that the marking data is processed by the signal acquisition device.

4. The near-infrared optical imaging system according to claim 1, characterized in that: The transmitting probe is used to transmit near-infrared light of at least one preset wavelength to the head of the subject, and the receiving probe is used to receive the near-infrared light emitted from the head of the subject.

5. The near-infrared optical imaging system according to any one of claims 1 to 4, characterized in that: The optical fiber cable comprises an optical fiber, a fabric layer and a jacket layer, wherein: The fabric layer is sleeved on the optical fiber, and in at least the middle section of the cable, the fabric layer is slidable relative to the optical fiber at least along the longitudinal direction of the optical fiber; and the extension of the fabric layer along the longitudinal direction is lower than a first threshold; The outer covering layer is sleeved on the fabric layer, and the outer covering layer is lightproof and flexible.

6. The near-infrared optical imaging system according to any one of claims 1 to 4, characterized in that: The backup transmitting probe and the backup receiving probe are installed in the corresponding area of ​​the occipital part of the head cap, or are installed correspondingly adjacent to at least part of the target transmitting probe and at least part of the target receiving probe, so as to replace the faulty probe located in the same cerebral hemisphere.

7. The near-infrared optical imaging system according to any one of claims 1 to 4, characterized in that: The cable has a first end connected to the transmitting probe or the receiving probe, and the cable is bounded into a bundle by a cable bundle assembly. The near-infrared optical imaging system also includes a first tensile member, which is connected between the head cap and a first position of the cable assembly, and the length of a portion of the cable between the first position and the first end is greater than the length of the first tensile member.

8. The near-infrared optical imaging system according to any one of claims 1 to 4, characterized in that: The cable has a second end connected to the signal acquisition device, and the cable is bounded into a bundle by a cable harness assembly. The near-infrared optical imaging system also includes a second tensile member, which is connected between the signal acquisition device and the second position of the cable assembly, and the length of the portion of the cable between the second position and the second end is greater than the length of the second tensile member.

9. The near-infrared optical imaging system according to any one of claims 1 to 4, characterized in that: The head cap covers a first brain region of the subject's frontal lobe, which is larger than the second brain region of the subject's occipital lobe; the head cap covers a third brain region of the subject's temporal lobe, which is larger than the second brain region.

10. The near-infrared optical imaging system according to any one of claims 1 to 4, characterized in that: The transmitting probe and the receiving probe are respectively fixedly connected to their respective upper buckles, and the transmitting probe and the receiving probe are detachably connected to the lower buckles of the corresponding mounting positions on the head cap through their respective upper buckles.

11. The near-infrared optical imaging system according to claim 10, characterized in that: The head cap is provided with first marks corresponding to the respective installation positions, and the upper buckles corresponding to the transmitting probe and the receiving probe are provided with second marks, wherein: For each of the transmitting probe and the receiving probe, the second mark on the corresponding upper buckle is associated with the corresponding first mark on the head cap.

12. The near-infrared optical imaging system according to any one of claims 1 to 4, characterized in that: The processing device is connected to the signal acquisition device by wire through a communication module, and the communication module is placed in the signal acquisition device.

13. The near-infrared optical imaging system according to any one of claims 1 to 4, characterized in that: The near-infrared optical imaging system further comprises a phantom device for testing the performance of the optical transmission path in the near-infrared optical imaging system, wherein the phantom device is portable and comprises a housing, a light attenuation component, and a storage module, wherein: The housing is provided with a communication interface and a plurality of probe interfaces arranged in pairs, wherein the probe interfaces arranged in pairs are used to plug in a pair of transmitting probes and receiving probes in the signal acquisition device; The optical attenuation component is arranged in the housing and includes a stacked filter layer and an attenuation body. The optical attenuation component is arranged corresponding to the light-emitting end of the transmitting probe and the light-receiving end of the receiving probe, so that the near-infrared light emitted by the transmitting probe is transmitted to the receiving probe via the filter layer and the attenuation body in sequence. The optical attenuation component is used to cause the near-infrared light on the optical path between the paired transmitting probe and the receiving probe to be optically attenuated with a calibrated attenuation parameter, wherein the difference between the calibrated attenuation parameter and the reference attenuation parameter is within a preset range; The storage module is disposed in the housing, the storage module stores the calibrated attenuation parameters, and the communication interface is used to output the calibrated attenuation parameters.

14. A method for using a near-infrared optical imaging system in a microgravity scenario, characterized in that: The near-infrared optical imaging system comprises a fixed component, a portable signal acquisition device, a transmitting probe connected to a power supply cable, a receiving probe connected to an optical fiber cable, a head cap and a processing device, the transmitting probe comprises a target transmitting probe and a spare transmitting probe, the receiving probe comprises a target receiving probe and a spare receiving probe, the signal acquisition device is reinforced to resist overload, the fixed component comprises a stand and a wearable component, the cables of the target probe and the spare probe of the ipsilateral cerebral hemisphere are tied tightly at a certain distance from the probe, and the method of use comprises: Fixing the signal acquisition device to the table through the stand, and installing the power supply cable and the optical fiber cable to the signal acquisition device, so that the transmitting probe and the receiving probe are connected to the signal acquisition device; Installing the target transmitting probe in the transmitting probe and the target receiving probe in the receiving probe at set positions on the head cap; Fixing the subject in front of the table, and wearing the head cap on the subject's head; Wearing the wearable device on the upper body of the subject, and using the cable fixing component in the wearable device to pass at least part of the cable through and fix it to the back of the subject; The signal acquisition device is used to acquire the brain function imaging time series data of the subject, and the brain function imaging time series data is sent to the processing device for display or analysis by the processing device.

15. The method for using the near-infrared optical imaging system according to claim 14, characterized in that: The method of collecting the brain function imaging time series data of the subject by using the signal collection device includes: Acquiring calibrated attenuation parameters of a phantom device, wherein the phantom device is used to simulate the attenuation of incident light in the subject; Acquiring an initial light intensity detection result of the outgoing light emitted from the phantom device after the incident light enters the detection environment of the phantom device; Determining a standard light intensity detection result of the optical transmission path in the near-infrared optical imaging system under a standard phantom detection environment based on the initial light intensity detection result and the calibrated attenuation parameter of the phantom device; Comparing the standard light intensity detection result with the standard light intensity range to determine the detection result of the light transmission path in the near-infrared optical imaging system; When the detection result of the light transmission path in the near-infrared optical imaging system is detection passed, the signal acquisition device is used to acquire the brain function imaging time series data of the subject.

Citation Information

Patent Citations

  • Evaluation method for working memory ability under simulated weightlessness condition based on cerebral blood flow

    CN110755041A

  • Simulation device for measuring performance of optical transmission path in near-infrared brain function imaging equipment

    CN118717057A

  • Optical fiber cable and near-infrared brain function imaging system with same

    CN118897365A