A simulated human chest-lung-breathing tumor model and a manufacturing method thereof

Abstract

The application discloses a kind of simulation human thoracic lung respiratory tumor model and its manufacturing method, belong to medical instrument field, using multiple shell mold assembly formation is provided with cavity lung shell mold, using flexible material forms hollow respiratory cavity structure, according to the location of tumor, liquid flexible material is injected into cavity, after flexible material solidification, metal ball of simulating tumor is placed, respiratory cavity structure is placed in cavity, according to the number of tumor and the location continues to inject liquid flexible material and place metal ball until cavity is filled to form the lung model containing tumor model, rib model is sleeved into lung model, multiple split mold is closed to lung model and forms chest mold, liquid flexible material is injected into chest mold, and solidification demolding obtains thoracic lung respiratory tumor model, the simulation human thoracic lung respiratory tumor model made simulates human respiration by inflation or deflation, accurately determines displacement change caused by tumor with respiration in the process of respiration.

Description

TECHNICAL FIELD

[0001] The present application relates to the field of medical devices, in particular to a simulation of human chest lung breathing tumor model and its manufacturing method. BACKGROUND

[0002] Most of the chest tumor radiotherapy is irradiated from the outside, and the accuracy of the radiation position is very high during radiotherapy. The patient cannot move or can only move in a very small range during the treatment. If the patient moves too much or the breathing amplitude is too large, it may cause the treatment area to move out of the treatment target area, affecting the treatment effect.

[0003] In the prior art, the position of the tumor in different postures of the patient is determined by establishing a lung breathing model. However, most of the lung breathing models are made of rigid materials and can only achieve a similar appearance. They cannot simulate the breathing effect, cannot realize the displacement change of the tumor caused by the human body breathing, or can only simulate the principle of breathing, cannot realize the effect of lung breathing expansion, and cannot realize the breathing linkage effect combined with the human chest and abdomen. Therefore, it is difficult to accurately determine the displacement change of the tumor caused by breathing during the breathing process. SUMMARY

[0004] In order to overcome the shortcomings of the prior art, one of the purposes of the present application is to provide a simulation of human chest lung breathing tumor model manufacturing method which can accurately determine the displacement change of the tumor caused by breathing during the breathing process.

[0005] In order to overcome the shortcomings of the prior art, the second purpose of the present application is to provide a simulation of human chest lung breathing tumor model which can accurately determine the displacement change of the tumor caused by breathing during the breathing process.

[0006] One of the purposes of the present application is achieved by the following technical solutions:

[0007] A simulation of human chest lung breathing tumor model manufacturing method, comprising the following steps:

[0008] Manufacturing lung shell mold: a plurality of shell molds are assembled to form a lung shell mold, and a cavity is formed inside the lung shell mold;

[0009] Manufacturing breathing cavity structure: a hollow breathing cavity structure is formed by using flexible material, and a flexible tube is provided on the breathing cavity structure, and the flexible tube is in communication with the hollow structure inside;

[0010] Lung model forming: according to the location of the tumor, inject liquid flexible material into the cavity, and after the flexible material solidifies, place a metal ball to simulate the tumor. Disassemble at least one of the shells to open the cavity, place two breathing cavity structures in the cavity, and assemble the disassembled shells to the lung shell mold. According to the number and location of the tumor, continue to inject liquid flexible material and place metal balls until the cavity is filled. The lung shell mold forms a lung model containing a tumor model.

[0011] Chest model forming: fit the rib model into the lung model, fold and assemble the multiple split molds around the lung model to form a chest mold, and the flexible tube extends from the rib model and the chest mold. Inject liquid flexible material into the chest mold, and after solidification, demold to obtain a chest-lung-breathing-tumor model.

[0012] Further, the step of making a breathing cavity structure is: placing a cavity inner mold in a cavity outer mold, injecting liquid flexible material between the cavity inner mold and the cavity outer mold, and solidifying the liquid flexible material to form a main body. Remove the main body from between the cavity inner mold and the cavity outer mold, place the main body into a cavity bottom sealing mold with liquid flexible material, form a sealing surface on the main body, and provide a connecting hole on the sealing surface. The flexible tube is fixed to the connecting hole.

[0013] Further, the flexible material is silicone.

[0014] Further, the lung model is made of silicone E615, the breathing cavity structure is made of silicone E615, and the chest model is made of silicone G05.

[0015] Further, in the lung model forming step, the metal ball is a tungsten ball.

[0016] Further, the method for making a simulated human chest-lung-breathing-tumor model further includes obtaining human data, and the step of obtaining human data is before the step of making a lung shell mold. The step of obtaining human data is: obtaining medical images of the human body, obtaining tumor quantity, size, and location information from the medical images, and obtaining lung, rib, and chest size data of the human body.

[0017] Further, in the step of making a lung shell mold, multiple shell molds are made by 3D printing according to the human lung size data, and in the step of forming a chest model, the split molds are made by 3D printing according to the human chest data.

[0018] Further, in the lung shell mold manufacturing method, the number of the shell molds is three, the three shell molds are a first shell mold, a second shell mold and a third shell mold, the first shell mold and the second shell mold are assembled to form a half lung model, the first shell mold is located above the second shell mold, the first shell mold is provided with a feeding hole, the feeding hole is located at the top of the first shell mold, and the third shell mold is fixed with the first shell mold and the second shell mold to form the lung shell mold.

[0019] The second purpose of the present application is achieved by the following technical scheme:

[0020] The simulation human chest-lung-breathing-tumor model is manufactured by any one of the simulation human chest-lung-breathing-tumor model manufacturing methods, and the simulation human chest-lung-breathing-tumor model comprises a chest model, a rib model, a lung model and a tumor model, the lung model is made of flexible material, the lung model has a hollow structure and is communicated with the outside through a flexible pipe, the tumor model is embedded in the lung model, the rib model is sleeved outside the lung model, the chest model is formed outside the rib model, the chest model is made of flexible material, and the simulation human breathing can be realized by inflating or deflating the flexible pipe.

[0021] Further, the lung model is made of silica gel E615, and the chest model is made of silica gel G05.

[0022] Compared with the prior art, the simulation human chest-lung-breathing-tumor model manufacturing method adopts a plurality of shell molds to assemble a lung shell mold, a cavity is formed in the lung shell mold, a hollow breathing cavity structure is formed by using flexible material, a flexible pipe is arranged on the breathing cavity structure, the flexible pipe is communicated with the hollow structure inside, liquid flexible material is injected into the cavity according to the position of the tumor, a metal ball is placed after the flexible material is solidified, the metal ball is used to simulate the tumor, at least one shell is disassembled to open the cavity, the breathing cavity structure is placed in the cavity, the disassembled shell is mounted to the lung shell mold, liquid flexible material is continuously injected and the metal ball is placed according to the number and position of the tumor until the cavity is filled, a lung model containing a tumor model is formed in the lung shell mold, a rib model is sleeved into the lung model, a plurality of split molds are folded and assembled around the lung model to form a chest mold, the flexible pipe extends from the rib model and the chest mold, liquid flexible material is injected into the chest mold, and a chest-lung-breathing-tumor model is obtained after solidification and demolding. Through the above steps, the simulation human chest-lung-breathing-tumor model can simulate human breathing by inflating or deflating, so that the displacement change of the tumor caused by breathing during the breathing process can be accurately judged. Attached Figure Description

[0023] Figure 1 This is a flowchart of the method for creating a simulated human chest and lung respiratory tumor model according to the present invention;

[0024] Figure 2 A three-dimensional drawing of the lung shell mold;

[0025] Figure 3 for Figure 2 A perspective view of the first shell mold of the lung shell mold;

[0026] Figure 4 for Figure 2 A perspective view of the second shell mold of the lung shell mold;

[0027] Figure 5 for Figure 2 A three-dimensional view of the lung shell mold in its open state;

[0028] Figure 6 A three-dimensional view of the external mold of the cavity;

[0029] Figure 7 A three-dimensional view of the mold inside the cavity;

[0030] Figure 8 A three-dimensional view of a cavity sealing mold;

[0031] Figure 9 A three-dimensional diagram of the structure of the breathing cavity;

[0032] Figure 10 A 3D model of a breast mold;

[0033] Figure 11 A three-dimensional view of a thoracic and pulmonary respiratory tumor model;

[0034] Figure 12 This is a three-dimensional diagram of the internal structure of a thoracic and pulmonary respiratory tumor model.

[0035] In the diagram: 10. Lung shell mold; 11. First shell mold; 110. Feeding hole; 111. First fixing hole; 112. Second fixing hole; 12. Second shell mold; 120. Third fixing hole; 13. Third shell mold; 130. Fourth fixing hole; 14. Cavity; 21. External cavity mold; 22. Internal cavity mold; 23. Bottom cavity mold; 230. Base plate; 231. Extension column; 30. Breathing cavity structure; 31. Main body; 32. Sealing surface; 33. Flexible tube; 40. Chest mold; 41. Split mold; 410. Sprue; 100. Chest and lung respiratory tumor model; 101. Chest model; 102. Rib model; 103. Lung model; 104. Tumor model. Detailed Implementation

[0036] The technical solutions in the embodiments of the present application will be clearly and completely described below with reference to the drawings in the embodiments of the present application. Obviously, the described embodiments are only a part of the embodiments of the present application, rather than all the embodiments of the present application. Based on the embodiments in the present application, all the other embodiments obtained by a person of ordinary skill in the art without creative effort belong to the scope of the present application.

[0037] Unless otherwise defined, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this application belongs. The terminology used in the description herein is for describing particular embodiments only and is not intended to be limiting of the application. As used in this description, the singular forms "a", "an" and "the" include plural references unless the context clearly dictates otherwise.

[0038] Please refer to Figure 1 The present application is a method for manufacturing a chest-lung-breathing-tumor model, comprising the following steps:

[0039] Manufacturing a lung shell mold: a plurality of shell molds are assembled to form a lung shell mold, and a cavity is formed inside the lung shell mold;

[0040] Manufacturing a breathing cavity structure: a hollow breathing cavity structure is formed by using a flexible material, and a flexible tube is arranged on the breathing cavity structure, and the flexible tube is in communication with the hollow structure inside;

[0041] Forming a lung model: according to the position of the tumor, liquid flexible material is injected into the cavity, and a metal ball is placed after the flexible material solidifies, the metal ball is used to simulate the tumor, at least one shell is disassembled to open the cavity, and two breathing cavity structures are placed in the cavity, the disassembled shell is installed to the lung shell mold, and liquid flexible material is continuously injected and the metal ball is placed according to the number and position of the tumor until the cavity is filled, and a lung model containing a tumor model is formed inside the lung shell mold;

[0042] Forming a chest model: the rib model is sleeved into the lung model, a plurality of split molds are folded and assembled around the lung model to form a chest mold, the flexible tube extends from the rib model and the chest mold, liquid flexible material is injected into the chest mold, and the chest-lung-breathing-tumor model is obtained after solidification and demolding.

[0043] The method for manufacturing the human chest-lung tumor breathing model further comprises the step of obtaining human data, which is performed before the step of manufacturing the lung shell mold. The step of obtaining human data specifically comprises the following steps: obtaining human medical images, obtaining tumor quantity, size, and location information from the medical images, and obtaining human lung, rib, and chest size data. The human medical images are obtained by CT, and three-dimensional modeling of the lung, tumor, rib, and chest is performed based on the human medical images.

[0044] Please continue to refer to Figures 2-3 The lung shell mold 10 is formed by detachably assembling a plurality of shell molds, so that the breathing cavity structure 30 can be placed in the lung shell mold 10 and the lung model 103 can be demolded after being formed. Specifically, the number of shell molds is three, and the three shell molds are a first shell mold 11, a second shell mold 12, and a third shell mold 13. The first shell mold 11, the second shell mold 12, and the third shell mold 13 are all formed by 3D printing based on the lung data obtained from the human medical images.

[0045] The first shell mold 11 is a quarter structure, and the first shell mold 11 is provided with a feeding hole 110 at the top to facilitate the subsequent addition of liquid flexible material. The first shell mold 11 is provided with a first fixing hole 111 and a second fixing hole 112. The first fixing hole 111 is located inside the first shell mold 11, and the second fixing hole 112 is located at the bottom of the first shell mold 11. The first fixing hole 111 is used to fix the first shell mold 11 and the third shell mold 13, and the second fixing hole 112 is used to fix the first shell mold 11 and the second shell mold 12.

[0046] The second shell mold 12 is a quarter structure, and the second shell mold 12 is provided with a third fixing hole 120. The third fixing hole 120 is fixed with the first shell mold 11.

[0047] The third shell mold 13 is a half structure, and the third shell mold 13 is provided with a fourth fixing hole 130. The fourth fixing hole 130 is fixed with the first shell mold 11.

[0048] The first shell mold 11, the second shell mold 12, and the third shell mold 13 are fixed with each other to form the lung shell mold 10. The lung shell mold 10 is a hollow structure, and a forming cavity 14 is formed inside.

[0049] Please continue to refer to Figures 6-9The step of manufacturing the breathing cavity structure 30 is specifically: placing the cavity inner mold 22 in the cavity outer mold 21, injecting liquid flexible material between the cavity inner mold 22 and the cavity outer mold 21, solidifying the liquid flexible material to form the main body 31, taking out the main body 31 from between the cavity inner mold 22 and the cavity outer mold 21, placing the main body 31 into the cavity bottom sealing mold 23 with the liquid flexible material, forming a sealing surface 32 on the main body 31, and providing a connecting hole on the sealing surface 32, and fixing the flexible tube 33 to the connecting hole.

[0050] Specifically, the cavity outer mold 21 is in a rectangular shape and is a hollow structure. The cavity inner mold 22 is also in a rectangular shape and is a hollow structure. The cavity bottom sealing mold 23 includes a bottom plate 230 and an extension column 231 extending from the bottom plate 230, and the extension column 231 is used to form the connecting hole. The flexible material is silicone, and further, the silicone E615 is used. The cavity outer mold 21, the cavity inner mold 22, and the cavity bottom sealing mold 23 are all formed according to the lung data 3D printed from human medical images. The flexible tube 33 is a silicone tube and is bonded to the connecting hole by silicone glue.

[0051] In the forming step of the lung model 103, the number, size, and location information of the tumor can be obtained through human medical images. Taking one tumor as an example, the forming process of the lung model 103 is described as follows: liquid flexible material is injected into the cavity 14 through the charging hole 110. In this embodiment, the liquid flexible material is silicone E615, and the silicone E615 is mixed with AB skin color in a one-to-one ratio, 200 ml of the mixture is poured into each of the two charging holes 110, and the volume of the mixture poured is determined by the location of the tumor. After the flexible material solidifies, a metal ball is placed in it, which serves as a tumor model 104 for simulating a tumor. In this embodiment, the metal ball is a tungsten ball. The diameter of the metal ball is determined by the size of the tumor. In this embodiment, the diameter of the metal ball is 1 cm. The first shell mold 11 is disassembled, as shown in FIG. 6, to expose the two cavities each containing 200 ml of silicone; the two breathing cavity structures 30 are placed in the cavities, the disassembled first shell mold 11 is installed to the lung shell mold 10, the flexible tube 33 extends out of the charging hole 110, the E615 mixed silicone liquid is poured into the charging hole 110 until it is full, and the lung model 103 containing the tumor model 104 is formed in the lung shell mold 10 after the solidification and demolding. Figure 5

[0052] Please continue to refer to Figure 10 ​The chest mold 40 comprises four separate molds 41, with a sprue 410 at the top. The chest model forming process is as follows: A 1cm thick layer of white clay is laid on a flat surface. The prepared lung model 103 is placed in the center and gently pressed down to secure it. Then, the rib model 102 is fitted over the lung model 103 from above, and the flexible tube 33 is removed from above. Finally, the four chest molds are joined together around the lung model, using clay for added fixation. The flexible tube 33 extends from the two sprue 410s at the top. After fixation, a 1:1 mixture of Guoyuan silicone G05 is poured in until full. After curing, the model is demolded the next day, completing the fabrication of the simulated human chest and lung breathing model.

[0053] Simulated human chest and lung breathing model, such as Figure 11 as well as Figure 12 As shown, the model includes a chest model 101, a rib model 102, a lung model 103, and a tumor model 104. The lung model 103 is made of flexible material, has a hollow structure, and is connected to the outside via a flexible tube 33. The tumor model 104 is embedded in the lung model 103. The rib model 102 is fitted onto the outside of the lung model 103. The chest model 101 is formed outside the rib model 102 and is made of flexible material. The chest model 101 and lung model 103 use silicone of different hardnesses to organically combine the lung breathing model and the chest and abdomen model. A tungsten ball is inserted to simulate a tumor. The lung model 103 is inflated and deflated via the flexible tube 33, achieving a synchronized breathing effect during inflation and deflation. The tumor's position changes continuously with respiration, allowing for precise determination of the tumor's displacement during breathing. This solves the problems of low simulation accuracy, unclear effects, and impracticality of traditional tumor breathing models.

[0054] The above embodiments merely illustrate several implementation methods of the present invention, and their descriptions are relatively specific and detailed, but they should not be construed as limiting the scope of the invention patent. It should be noted that, for those skilled in the art, several modifications and improvements can be made without departing from the concept of the present invention. These are all equivalent modifications and improvements made to the above embodiments based on the essential technology of the present invention, and all of these fall within the protection scope of the present invention.

Claims

1. A method for creating a simulated human chest and lung respiratory tumor model, characterized in that, The method comprises the following steps: Manufacturing a lung shell mold: a plurality of shell molds are assembled to form a lung shell mold, the inside of the lung shell mold is formed into a cavity, the number of the shell molds is three, the three shell molds are a first shell mold, a second shell mold and a third shell mold, the first shell mold and the second shell mold are assembled to form a half lung model, the first shell mold is located above the second shell mold, the first shell mold is provided with a feeding hole, the feeding hole is located at the top of the first shell mold, the third shell mold is fixed with the first shell mold and the second shell mold to form the lung shell mold; Manufacturing a breathing cavity structure: a hollow breathing cavity structure is formed by using a flexible material, the breathing cavity structure is provided with a flexible tube, the flexible tube is in communication with the hollow structure inside, a cavity inner mold is placed in a cavity outer mold, liquid flexible material is injected between the cavity inner mold and the cavity outer mold, the liquid flexible material is solidified to form a main body, the main body is taken out from between the cavity inner mold and the cavity outer mold, the main body is placed into a cavity bottom sealing mold with liquid flexible material, a sealing surface is formed on the main body, the sealing surface is provided with a connecting hole, and the flexible tube is fixed in the connecting hole; Lung model forming: according to the location of the tumor, liquid flexible material is injected into the cavity, a metal ball is placed after the flexible material is solidified, the metal ball is used to simulate the tumor, at least one shell is disassembled to open the cavity, two breathing cavity structures are placed in the cavity, the disassembled shell is installed to the lung shell mold, and according to the number and location of the tumor, liquid flexible material is continuously injected and a metal ball is placed until the cavity is filled, a lung model containing a tumor model is formed in the lung shell mold; Chest model forming: a rib model is sleeved into the lung model, a plurality of split molds are folded and assembled around the lung model to form a chest mold, the flexible tube extends from the rib model and the chest mold, liquid flexible material is injected into the chest mold, and a chest-lung-breathing-tumor model is obtained after solidification and demolding.

2. The method of claim 1, wherein the method further comprises: The flexible material is silica gel. ​ 3. The method of claim 2, wherein the method further comprises: The lung model is made of silica gel E615, the breathing cavity structure is made of silica gel E615, and the chest model is made of silica gel G05. ​ 4. The method of claim 1, wherein the method further comprises: providing a lung tumor model having a tumor volume of about 0.1 cm3 to about 1.0 cm3. In the lung model forming step, the metal ball is a tungsten ball.

5. The method of claim 1, wherein the method further comprises: The method for manufacturing a simulated human chest-lung-breathing-tumor model further comprises obtaining human data, the obtaining human data step is located before the manufacturing lung shell mold step, and the obtaining human data specifically comprises: obtaining human medical images, obtaining tumor quantity, size and location information according to the medical images, and obtaining human lung, rib and chest size data. ​ 6. The method of claim 5, wherein the method further comprises: providing a lung tumor model having a tumor volume of about 0.1 cm3 to about 1.0 cm3. In the step of manufacturing the lung shell mold, a plurality of the shell molds are manufactured by 3D printing according to human lung size data, and in the step of forming the chest model, the split mold is manufactured by 3D printing according to human chest size data.

7. A simulated human thoracic-lung-breathing tumor model, which is prepared by the method according to any one of claims 1 to 6. The simulated human chest-lung-breathing-tumor model comprises a chest model, a rib model, a lung model and a tumor model, the lung model is made of flexible material, the lung model is a hollow structure and is in communication with the outside through a flexible tube, the tumor model is embedded in the lung model, the rib model is sleeved outside the lung model, the chest model is formed outside the rib model, the chest model is made of flexible material, and inflation or deflation through the flexible tube can simulate human respiration.

8. The simulated human thoracic-lung tumor model of claim 7, wherein: The lung model is made of silicone E615, and the chest model is made of silicone G05.

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