Scutellaria baicalensis root extract-containing soothing, cleaning and antibacterial composition as well as preparation method and application thereof

Abstract

The invention relates to the technical field of cosmetics, and discloses a relieving, cleaning and bacteriostatic composition containing a scutellaria baicalensis root extract and a preparation method and application of the relieving, cleaning and bacteriostatic composition. Sodium methyl cocoyl taurate and lauryl glucoside are added into the composition to serve as solubilizers to promote the solubility of the scutellaria baicalensis root extract in water; sodium methyl cocoyl taurate, lauryl glucoside and cocamidopropyl betaine are used as surfactants and have the technical effects of sterilization, strong detergency, strong foaming power, no toxicity, no harm and small irritation, and the scutellaria baicalensis root extract has the effects of repairing skin, inhibiting bacteria and sterilizing; the antioxidant can improve the stability of the composition, prolong the shelf life of the product, ensure the solubility of the scutellaria baicalensis root extract, and ensure that the problem that particles are separated out and precipitated after the product is stored for a long time can not occur all the time.

Description

Technical Field

[0001] The present invention relates to the technical field of cosmetics, and in particular to a soothing, cleaning and antibacterial composition containing a scutellaria root extract, a preparation method and an application thereof. Background Art

[0002] Scutellaria root extract is a flavonoid compound extracted and separated from the root of Scutellaria baicalensis. It is a light yellow powder with significant biological activity. It has antibacterial, diuretic, anti-inflammatory, anti-allergic, antispasmodic and anti-cancer effects, and has important medical value. Baicalin in Scutellaria root extract also has the effects of absorbing ultraviolet rays, scavenging oxygen free radicals, inhibiting melanin production, soothing skin inflammation, improving skin tolerance and repairing skin barrier. The effective concentration of Scutellaria root extract is low, and it is also an important functional active raw material for cosmetics. However, since Scutellaria root extract is not easy to dissolve in water, problems such as particle precipitation will occur, which also limits the application of Scutellaria root extract in aqueous preparations.

[0003] At present, cleaning products on the market are mainly divided into several categories: one is a system with sulfate surfactant as the main surfactant, which has a decent cleaning ability but is very irritating to the skin; the other is a pure amino acid system that is advertised as safe, but has the disadvantages of weak cleaning ability, incomplete cleaning and high cost; and another is a system with soap as the main surfactant and a small amount of anionic surfactant. This type of product has too strong degreasing ability and will cause certain damage to the skin barrier if used for a long time. Surfactants are chemical substances that can reduce the surface tension of liquids. They can help detergents, facial cleansers, shampoos and other cleaning products to better remove dirt and clean, so as to obtain a clean and comfortable use experience. However, the unreasonable use of surfactants, especially for special groups such as infant skin with weak skin barrier, dry skin and sensitive skin, may cause adverse reactions such as dry skin, sensitivity and allergies. Patent CN116687778B discloses a mild, tear-free, non-irritating amino acid cleansing foam for children and its preparation method. The cleansing product is mild, tear-free, and non-irritating, but due to its low surfactant content, its cleaning ability is poor and it cannot meet the use of shampoo, hand sanitizer and other products that require strong decontamination and cleaning power. Therefore, it is necessary to develop a composition that is mild, non-irritating, reasonably priced, and has appropriate cleaning effects, while also having certain skin repair functions. Summary of the invention

[0004] In order to overcome the problem of poor solubility of scutellaria root extract in water products and low stability in the prior art, the present invention provides a soothing, cleaning and antibacterial composition containing scutellaria root extract, a preparation method and an application thereof. In the composition, sodium methyl cocoyl taurate and lauryl glucoside are added as solubilizers to promote the solubility of scutellaria root extract in water and increase the content of scutellaria root extract in the aqueous product. Sodium methyl cocoyl taurate, lauryl glucoside and cocamidopropyl betaine as surfactants have the technical effects of strong bactericidal, detersive and foaming power, non-toxicity, harmlessness and low irritation. The scutellaria root extract has the effects of repairing skin and inhibiting and killing bacteria. The antioxidant can improve the stability of the composition, increase the shelf life of the product, ensure the solubility of the scutellaria root extract, and ensure that the product will not have the problem of particle precipitation during long-term storage.

[0005] The specific technical scheme of the present invention is: A soothing, cleaning and antibacterial composition containing scutellaria root extract, comprising, by weight: 0.01-2 parts of Scutellaria baicalensis root extract, 3-8 parts of sodium methyl cocoyl taurate, 5-8 parts of lauryl glucoside, 5-8 parts of cocamidopropyl betaine, Antioxidant 0.01-0.2 parts, 20-40 parts of water.

[0006] Preferably, the antioxidant is one or both of sodium sulfite and sodium pyrosulfite.

[0007] Preferably, the baicalin content in the Scutellaria baicalensis root extract is ≥80%.

[0008] Preferably, the purity of the sodium methyl cocoyl taurate is ≥27%.

[0009] Preferably, the purity of cocamidopropyl betaine is ≥35%.

[0010] The invention provides a soothing, cleaning and antibacterial composition containing a scutellaria root extract. The composition comprises a scutellaria root extract, sodium methyl cocoyl taurate, lauryl glucoside, cocamidopropyl betaine and water. In the composition, sodium methyl cocoyl taurate is added to water to form an alkaline solution, and the alkaline solution can increase the solubility of the extract. In addition, the alkaline solution obtained by compounding sodium methyl cocoyl taurate and lauryl glucoside can further ensure the solubility of the scutellaria root extract, and can ensure that the product will not have the problem of particle precipitation during long-term storage.

[0011] The flavonoid components in Scutellaria baicalensis root extract can inhibit inflammatory responses. At the same time, Scutellaria baicalensis extract has a strong inhibitory effect on hyaluronidase, which can significantly reduce the probability of skin allergies. Scutellaria baicalensis root extract also has inhibitory effects on a variety of bacteria and viruses.

[0012] Methyl cocoyl taurate is an amino acid type surfactant with rich, delicate and stable foam. It has good compatibility and excellent washing, wetting, emulsifying and dispersing abilities.

[0013] Lauryl glucoside is a nonionic surfactant with the characteristics of common nonionic and anionic surfactants, good foaming power, high detergency, low surface tension, no cloud point, adjustable HLB value, strong wetting power, significant detergency, rich and delicate foam, non-toxic, harmless, no irritation to the skin, rapid and thorough biodegradation, can be compounded with any type of surfactant, with obvious synergistic effect, significant thickening effect, easy to dilute, no gel phenomenon, easy to use. It is also resistant to strong alkali, strong acid, hard water, strong salt resistance, and has unique properties such as sterilization and enzyme activity improvement. It is a green surfactant with comprehensive performance.

[0014] Cocamidopropyl betaine is a zwitterionic surfactant that has excellent stability under acidic and alkaline conditions, showing cationic and anionic properties respectively. It is often used with anionic, cationic and nonionic surfactants, and has good compatibility. It has low irritation, is easily soluble in water, is stable to acid and alkali, has a lot of foam, has strong detergency, and has excellent thickening, softness, bactericidal, antistatic, and hard water resistance.

[0015] A method for preparing the above-mentioned soothing, cleaning and antibacterial composition containing scutellaria root extract comprises the following steps: adding sodium methyl cocoyl taurate and lauryl glucoside to water, heating and stirring at 60-65° C. until dissolved, cooling to 40-50° C. after dissolution, adding scutellaria root extract and stirring until uniform, then adding cocamidopropyl betaine and stirring until uniform, and then adding an antioxidant and stirring evenly to prepare a soothing, cleaning and antibacterial composition containing scutellaria root extract.

[0016] A soothing, cleaning and antibacterial composition containing scutellaria root extract is used in cosmetics. Cosmetics are made from cosmetic raw materials, wherein the cosmetic raw materials include the soothing, cleaning and antibacterial composition containing scutellaria root extract.

[0017] Preferably, the soothing, cleaning and antibacterial composition containing the scutellaria root extract is added in an amount of 30 to 60%.

[0018] Preferably, the cosmetic is one of an aqueous solution, an emulsion and an ointment.

[0019] Preferably, the cosmetic is one of shampoo, shower gel, facial cleanser and hand soap.

[0020] Compared with the prior art, this application has the following technical effects: The present invention provides a soothing, cleaning and antibacterial composition containing scutellaria root extract, a preparation method and an application thereof. In the composition, sodium methyl cocoyl taurate and lauryl glucoside are added as solubilizers to promote the solubility of the scutellaria root extract in water and increase the content of the scutellaria root extract in an aqueous product. Sodium methyl cocoyl taurate, lauryl glucoside and cocamidopropyl betaine are used as surfactants and have the technical effects of strong bactericidal, strong detergency and foaming power, being non-toxic, harmless and having low irritation. The scutellaria root extract has the effects of repairing skin and inhibiting and killing bacteria. The antioxidant can improve the stability of the composition, increase the shelf life of the product, ensure the solubility of the scutellaria root extract, and ensure that the product will not have the problem of particle precipitation during long-term storage. DETAILED DESCRIPTION

[0021] The present invention will be further described below in conjunction with the embodiments.

[0022] Embodiment 1: A soothing, cleaning and antibacterial composition containing scutellaria root extract, comprising, by mass, 0.05 parts of scutellaria root extract, 3 parts of sodium methyl cocoyl taurate, 5 parts of lauryl glucoside, 5 parts of cocamidopropyl betaine, 0.01 parts of an antioxidant (sodium sulfite) and 20 parts of water.

[0023] A method for preparing the above-mentioned soothing, cleaning and antibacterial composition containing Scutellaria baicalensis root extract comprises the following steps: Weigh scutellaria root extract, sodium methyl cocoyl taurate, lauryl glucoside, cocamidopropyl betaine, sodium sulfite and water according to the mass proportion of the above raw materials, add sodium methyl cocoyl taurate and lauryl glucoside to water, stir and heat to a temperature of 60-65°C. After complete dissolution, start to cool down. After cooling to 40-45°C, add scutellaria root extract and stir evenly, then add cocamidopropyl betaine and stir evenly, then add sodium sulfite and stir evenly to prepare a soothing, cleaning and antibacterial composition containing scutellaria root extract.

[0024] An application of the soothing, cleansing and antibacterial composition containing scutellaria root extract in shampoo comprises the following steps: mixing shampoo raw materials evenly to prepare a soothing, cleansing and antibacterial shampoo, wherein the shampoo raw materials are 40% by mass of the soothing, cleansing and antibacterial composition containing scutellaria root extract, 5% by mass of acrylic acid (ester) copolymer, 0.5% by mass of phenoxyethanol, 0.3% by mass of sodium benzoate, 0.3% by mass of essence and the remainder by mass of water.

[0025] Embodiment 2: A soothing, cleaning and antibacterial composition containing scutellaria root extract, comprising, by mass, 2 parts of scutellaria root extract, 8 parts of sodium methyl cocoyl taurate, 8 parts of lauryl glucoside, 8 parts of cocamidopropyl betaine, 0.2 parts of an antioxidant (sodium sulfite) and 40 parts of water.

[0026] A method for preparing the above-mentioned soothing, cleaning and antibacterial composition containing Scutellaria baicalensis root extract comprises the following steps: Weigh scutellaria root extract, sodium methyl cocoyl taurate, lauryl glucoside, cocamidopropyl betaine, sodium sulfite and water according to the mass proportion of the above raw materials, add sodium methyl cocoyl taurate and lauryl glucoside to water, stir and heat to a temperature of 60-65°C. After complete dissolution, start to cool down. After cooling to 40-45°C, add scutellaria root extract and stir evenly, then add cocamidopropyl betaine and stir evenly, then add sodium sulfite and stir evenly to prepare a soothing, cleaning and antibacterial composition containing scutellaria root extract.

[0027] An application of the soothing, cleansing and antibacterial composition containing scutellaria root extract in shampoo comprises the following steps: mixing shampoo raw materials evenly to prepare a soothing, cleansing and antibacterial shampoo, wherein the shampoo raw materials are 40% by mass of the soothing, cleansing and antibacterial composition containing scutellaria root extract, 5% by mass of acrylic acid (ester) copolymer, 0.5% by mass of phenoxyethanol, 0.3% by mass of sodium benzoate, 0.3% by mass of essence and the remainder by mass of water.

[0028] Embodiment 3: A soothing, cleaning and antibacterial composition containing scutellaria root extract, comprising, by mass, 0.5 parts of scutellaria root extract, 6 parts of sodium methyl cocoyl taurate, 6 parts of lauryl glucoside, 6 parts of cocamidopropyl betaine, 0.1 parts of an antioxidant (sodium sulfite) and 30 parts of water.

[0029] A method for preparing the above-mentioned soothing, cleaning and antibacterial composition containing Scutellaria baicalensis root extract comprises the following steps: Weigh scutellaria root extract, sodium methyl cocoyl taurate, lauryl glucoside, cocamidopropyl betaine, sodium sulfite and water according to the mass proportion of the above raw materials, add sodium methyl cocoyl taurate and lauryl glucoside to water, stir and heat to a temperature of 60-65°C. After complete dissolution, start to cool down. After cooling to 40-45°C, add scutellaria root extract and stir evenly, then add cocamidopropyl betaine and stir evenly, then add sodium sulfite and stir evenly to prepare a soothing, cleaning and antibacterial composition containing scutellaria root extract.

[0030] An application of the soothing, cleansing and antibacterial composition containing scutellaria root extract in shampoo comprises the following steps: mixing shampoo raw materials evenly to prepare a soothing, cleansing and antibacterial shampoo, wherein the shampoo raw materials are 40% by mass of the soothing, cleansing and antibacterial composition containing scutellaria root extract, 5% by mass of acrylic acid (ester) copolymer, 0.5% by mass of phenoxyethanol, 0.3% by mass of sodium benzoate, 0.3% by mass of essence and the remainder by mass of water.

[0031] Embodiment 4: A soothing, cleaning and antibacterial composition containing scutellaria root extract, comprising, by mass, 0.5 parts of scutellaria root extract, 6 parts of sodium methyl cocoyl taurate, 6 parts of lauryl glucoside, 6 parts of cocamidopropyl betaine, 0.1 parts of an antioxidant (sodium metabisulfite) and 30 parts of water.

[0032] A method for preparing the above-mentioned soothing, cleaning and antibacterial composition containing Scutellaria baicalensis root extract comprises the following steps: Weigh scutellaria root extract, sodium methyl cocoyl taurate, lauryl glucoside, cocamidopropyl betaine, sodium sulfite and water according to the mass proportion of the above raw materials, add sodium methyl cocoyl taurate and lauryl glucoside to water, stir and heat to a temperature of 60-65°C. After complete dissolution, start to cool down. After cooling to 40-45°C, add scutellaria root extract and stir evenly, then add cocamidopropyl betaine and stir evenly, then add sodium sulfite and stir evenly to prepare a soothing, cleaning and antibacterial composition containing scutellaria root extract.

[0033] An application of the soothing, cleansing and antibacterial composition containing scutellaria root extract in shampoo comprises the following steps: mixing shampoo raw materials evenly to prepare a soothing, cleansing and antibacterial shampoo, wherein the shampoo raw materials are 40% by mass of the soothing, cleansing and antibacterial composition containing scutellaria root extract, 5% by mass of acrylic acid (ester) copolymer, 0.5% by mass of phenoxyethanol, 0.3% by mass of sodium benzoate, 0.3% by mass of essence and the remainder by mass of water.

[0034] Embodiment 5: A soothing, cleaning and antibacterial composition containing scutellaria root extract, comprising, by mass, 0.5 parts of scutellaria root extract, 6 parts of sodium methyl cocoyl taurate, 6 parts of lauryl glucoside, 6 parts of cocamidopropyl betaine, 0.1 parts of antioxidants (0.05 parts of sodium metabisulfite and 0.05 parts of sodium sulfite) and 30 parts of water.

[0035] A method for preparing the above-mentioned soothing, cleaning and antibacterial composition containing Scutellaria baicalensis root extract comprises the following steps: Weigh scutellaria root extract, sodium methyl cocoyl taurate, lauryl glucoside, cocamidopropyl betaine, sodium sulfite and water according to the mass proportion of the above raw materials, add sodium methyl cocoyl taurate and lauryl glucoside to water, stir and heat to a temperature of 60-65°C. After complete dissolution, start to cool down. After cooling to 40-45°C, add scutellaria root extract and stir evenly, then add cocamidopropyl betaine and stir evenly, then add sodium sulfite and stir evenly to prepare a soothing, cleaning and antibacterial composition containing scutellaria root extract.

[0036] An application of the soothing, cleansing and antibacterial composition containing scutellaria root extract in shampoo comprises the following steps: mixing shampoo raw materials evenly to prepare a soothing, cleansing and antibacterial shampoo, wherein the shampoo raw materials are 40% by mass of the soothing, cleansing and antibacterial composition containing scutellaria root extract, 5% by mass of acrylic acid (ester) copolymer, 0.5% by mass of phenoxyethanol, 0.3% by mass of sodium benzoate, 0.3% by mass of essence and the remainder by mass of water.

[0037] Embodiment 6: A soothing, cleaning and antibacterial composition containing scutellaria root extract, comprising, by mass, 0.05 parts of scutellaria root extract, 3 parts of sodium methyl cocoyl taurate, 5 parts of lauryl glucoside, 5 parts of cocamidopropyl betaine, 0.01 parts of an antioxidant (sodium sulfite) and 20 parts of water.

[0038] A method for preparing the above-mentioned soothing, cleaning and antibacterial composition containing Scutellaria baicalensis root extract comprises the following steps: Weigh scutellaria root extract, sodium methyl cocoyl taurate, lauryl glucoside, cocamidopropyl betaine, sodium sulfite and water according to the mass proportion of the above raw materials, add sodium methyl cocoyl taurate and lauryl glucoside to water, stir and heat to a temperature of 60-65°C. After complete dissolution, start to cool down. After cooling to 40-45°C, add scutellaria root extract and stir evenly, then add cocamidopropyl betaine and stir evenly, then add sodium sulfite and stir evenly to prepare a soothing, cleaning and antibacterial composition containing scutellaria root extract.

[0039] An application of the soothing, cleansing and antibacterial composition containing scutellaria root extract in cleansing bubbles comprises the following steps: mixing the cleansing bubble raw materials evenly to form soothing, cleansing and antibacterial cleansing bubbles, wherein the cleansing bubble raw materials are 50% by mass of the soothing, cleansing and antibacterial composition containing scutellaria root extract, 0.5% by mass of 1,2-hexanediol, 6% by mass of glycerol, 0.3% by mass of sodium benzoate and the remainder by mass of water.

[0040] Embodiment 7: A soothing, cleaning and antibacterial composition containing scutellaria root extract, comprising, by mass, 0.5 parts of scutellaria root extract, 6 parts of sodium methyl cocoyl taurate, 6 parts of lauryl glucoside, 6 parts of cocamidopropyl betaine, 0.1 parts of an antioxidant (sodium metabisulfite) and 30 parts of water.

[0041] A method for preparing the above-mentioned soothing, cleaning and antibacterial composition containing Scutellaria baicalensis root extract comprises the following steps: Weigh scutellaria root extract, sodium methyl cocoyl taurate, lauryl glucoside, cocamidopropyl betaine, sodium sulfite and water according to the mass proportion of the above raw materials, add sodium methyl cocoyl taurate and lauryl glucoside to water, stir and heat to a temperature of 60-65°C. After complete dissolution, start to cool down. After cooling to 40-45°C, add scutellaria root extract and stir evenly, then add cocamidopropyl betaine and stir evenly, then add sodium sulfite and stir evenly to prepare a soothing, cleaning and antibacterial composition containing scutellaria root extract.

[0042] An application of the soothing, cleansing and antibacterial composition containing scutellaria root extract in cleansing bubbles comprises the following steps: mixing the cleansing bubble raw materials evenly to form soothing, cleansing and antibacterial cleansing bubbles, wherein the cleansing bubble raw materials are 50% by mass of the soothing, cleansing and antibacterial composition containing scutellaria root extract, 0.5% by mass of 1,2-hexanediol, 6% by mass of glycerol, 0.3% by mass of sodium benzoate and the remainder by mass of water.

[0043] Embodiment 8: A soothing, cleaning and antibacterial composition containing scutellaria root extract, comprising, by mass, 0.5 parts of scutellaria root extract, 6 parts of sodium methyl cocoyl taurate, 6 parts of lauryl glucoside, 6 parts of cocamidopropyl betaine, 0.1 parts of antioxidants (0.05 parts of sodium metabisulfite and 0.05 parts of sodium sulfite) and 30 parts of water.

[0044] A method for preparing the above-mentioned soothing, cleaning and antibacterial composition containing Scutellaria baicalensis root extract comprises the following steps: Weigh scutellaria root extract, sodium methyl cocoyl taurate, lauryl glucoside, cocamidopropyl betaine, sodium sulfite and water according to the mass proportion of the above raw materials, add sodium methyl cocoyl taurate and lauryl glucoside to water, stir and heat to a temperature of 60-65°C. After complete dissolution, start to cool down. After cooling to 40-45°C, add scutellaria root extract and stir evenly, then add cocamidopropyl betaine and stir evenly, then add sodium sulfite and stir evenly to prepare a soothing, cleaning and antibacterial composition containing scutellaria root extract.

[0045] An application of the soothing, cleansing and antibacterial composition containing scutellaria root extract in cleansing bubbles comprises the following steps: mixing the cleansing bubble raw materials evenly to form soothing, cleansing and antibacterial cleansing bubbles, wherein the cleansing bubble raw materials are 50% by mass of the soothing, cleansing and antibacterial composition containing scutellaria root extract, 0.5% by mass of 1,2-hexanediol, 6% by mass of glycerol, 0.3% by mass of sodium benzoate and the remainder by mass of water.

[0046] Embodiment 9: A soothing, cleaning and antibacterial composition containing scutellaria root extract, comprising, by mass, 0.05 parts of scutellaria root extract, 3 parts of sodium methyl cocoyl taurate, 5 parts of lauryl glucoside, 5 parts of cocamidopropyl betaine, 0.01 parts of an antioxidant (sodium sulfite) and 20 parts of water.

[0047] A method for preparing the above-mentioned soothing, cleaning and antibacterial composition containing Scutellaria baicalensis root extract comprises the following steps: Weigh scutellaria root extract, sodium methyl cocoyl taurate, lauryl glucoside, cocamidopropyl betaine, sodium sulfite and water according to the mass proportion of the above raw materials, add sodium methyl cocoyl taurate and lauryl glucoside to water, stir and heat to a temperature of 60-65°C. After complete dissolution, start to cool down. After cooling to 40-45°C, add scutellaria root extract and stir evenly, then add cocamidopropyl betaine and stir evenly, then add sodium sulfite and stir evenly to prepare a soothing, cleaning and antibacterial composition containing scutellaria root extract.

[0048] An application of the soothing, cleaning and antibacterial composition containing scutellaria root extract in hand soap comprises the following steps: mixing hand soap raw materials evenly to prepare soothing, cleaning and antibacterial hand soap, wherein the hand soap raw materials are 40% by mass of the soothing, cleaning and antibacterial composition containing scutellaria root extract, 5% by mass of butylene glycol and the balance of water.

[0049] Embodiment 10: A soothing, cleaning and antibacterial composition containing scutellaria root extract, comprising, by mass, 2 parts of scutellaria root extract, 8 parts of sodium methyl cocoyl taurate, 8 parts of lauryl glucoside, 8 parts of cocamidopropyl betaine, 0.2 parts of an antioxidant (sodium sulfite) and 40 parts of water.

[0050] A method for preparing the above-mentioned soothing, cleaning and antibacterial composition containing Scutellaria baicalensis root extract comprises the following steps: Weigh scutellaria root extract, sodium methyl cocoyl taurate, lauryl glucoside, cocamidopropyl betaine, sodium sulfite and water according to the mass proportion of the above raw materials, add sodium methyl cocoyl taurate and lauryl glucoside to water, stir and heat to a temperature of 60-65°C. After complete dissolution, start to cool down. After cooling to 40-45°C, add scutellaria root extract and stir evenly, then add cocamidopropyl betaine and stir evenly, then add sodium sulfite and stir evenly to prepare a soothing, cleaning and antibacterial composition containing scutellaria root extract.

[0051] An application of the soothing, cleaning and antibacterial composition containing scutellaria root extract in hand soap comprises the following steps: mixing hand soap raw materials evenly to prepare soothing, cleaning and antibacterial hand soap, wherein the hand soap raw materials are 40% by mass of the soothing, cleaning and antibacterial composition containing scutellaria root extract, 5% by mass of butylene glycol and the balance of water.

[0052] Embodiment 11: A soothing, cleaning and antibacterial composition containing scutellaria root extract, comprising, by mass, 0.5 parts of scutellaria root extract, 6 parts of sodium methyl cocoyl taurate, 6 parts of lauryl glucoside, 6 parts of cocamidopropyl betaine, 0.1 parts of an antioxidant (sodium sulfite) and 30 parts of water.

[0053] A method for preparing the above-mentioned soothing, cleaning and antibacterial composition containing Scutellaria baicalensis root extract comprises the following steps: Weigh scutellaria root extract, sodium methyl cocoyl taurate, lauryl glucoside, cocamidopropyl betaine, sodium sulfite and water according to the mass proportion of the above raw materials, add sodium methyl cocoyl taurate and lauryl glucoside to water, stir and heat to a temperature of 60-65°C. After complete dissolution, start to cool down. After cooling to 40-45°C, add scutellaria root extract and stir evenly, then add cocamidopropyl betaine and stir evenly, then add sodium sulfite and stir evenly to prepare a soothing, cleaning and antibacterial composition containing scutellaria root extract.

[0054] An application of the soothing, cleaning and antibacterial composition containing scutellaria root extract in hand soap comprises the following steps: mixing hand soap raw materials evenly to prepare soothing, cleaning and antibacterial hand soap, wherein the hand soap raw materials are 40% by mass of the soothing, cleaning and antibacterial composition containing scutellaria root extract, 5% by mass of butylene glycol and the balance of water.

[0055] Comparative Example 1: Compared with Example 1, in Comparative Example 1, sodium methyl cocoyl taurate and lauryl glucoside were not added.

[0056] Comparative Example 2: Compared with the examples, no lauryl glucoside was added in Comparative Example 2.

[0057] Comparative Example 3: Compared with the examples, no antioxidant was added in Comparative Example 3.

[0058] Comparative Example 4: Compared with the examples, in Comparative Example 4, no Scutellaria baicalensis root extract was added.

[0059] Comparative Example 5: Compared with the example, in Comparative Example 5, an equal amount of Scutellaria baicalensis root extract is replaced by sodium lauryl alcohol polyether sulfate.

[0060] Comparative Example 6: Compared with the embodiment, in Comparative Example 5, an equal amount of Scutellaria baicalensis root extract was replaced by Portulaca oleracea extract.

[0061] Test example 1: The compositions prepared in the above Examples 1 to 5 and Comparative Examples 1 to 2 were tested, and the test items included: immediate solubility, 48-hour stability and antioxidant properties; Instant solubility test: After the soothing, cleaning and antibacterial composition containing scutellaria root extract is prepared, the texture of the composition is immediately observed; 48-hour stability test: After the soothing, cleaning and antibacterial composition containing scutellaria root extract is left at room temperature for 48 hours, the texture of the composition is observed; Antioxidant test: After the soothing, cleaning and antibacterial composition containing scutellaria root extract is stored at 45° C. for 14 days, the color of the composition is observed; the test results are shown in Table 1; Table 1 Immediate solubility, 48-hour stability and antioxidant properties Instant solubility 48 hours stability Antioxidant Example 1 Clarity and transparency Clarity and transparency yellow Example 2 Clarity and transparency Clarity and transparency yellow Example 3 Clarity and transparency Clarity and transparency yellow Example 4 Clarity and transparency Clarity and transparency yellow Example 5 Clarity and transparency Clarity and transparency yellow Comparative Example 1 There are suspended particles, opaque There is precipitation yellow Comparative Example 2 Clarity and transparency There is sedimentation yellow Comparative Example 3 There are suspended particles, opaque There is sedimentation brown As shown in Table 1, by analyzing the solubility results, Examples 1 to 5 added sodium methyl cocoyl taurate and lauryl glucoside. Compared with Comparative Example 1, the addition of sodium methyl cocoyl taurate and lauryl glucoside can significantly increase the immediate solubility of the Scutellaria baicalensis root extract; by analyzing the 48-hour stability results, Examples 1 to 5 added sodium methyl cocoyl taurate and lauryl glucoside and remained clear and transparent after being placed for 48 hours, while the composition of Comparative Example 2, which only added sodium methyl cocoyl taurate, had precipitation after being placed for 48 hours. The above results show that the sodium methyl cocoyl taurate and lauryl glucoside obtained by the invention can increase the solubility of the scutellaria root extract during long-term storage, so that the scutellaria root extract can still maintain excellent solubility during long-term storage after being dissolved; after analyzing the antioxidant results, it was found that after adding the antioxidant, the color of the composition did not change significantly after being stored at high temperature for 14 days, while the color of the composition without adding the antioxidant changed from yellow to brown after being stored at high temperature for 14 days. The above results show that the antioxidant of the present application has an excellent antioxidant effect on the composition.

[0062] Test example 2: The compositions prepared in Examples 1 to 5 and Comparative Example 4 were tested for eye irritation, and eye irritation scores were performed by the chicken embryo chorioallantoic membrane (HET-CAM) test method to evaluate the risk of eye irritation of the composition and the safety of the composition; the test steps included: placing eggs incubated for 10 days on an egg rack with the air chamber end facing upward. Under the light, the eggshell at the air chamber end was broken with the toothed tweezers, and the eggshell was carefully peeled off with curved tweezers. 2 ml of saline was dripped, the egg membrane was soaked, the saline was sucked off, the egg membrane was peeled off with curved tweezers, and the integrity of the CAM was observed. If the CAM was damaged, it was discarded, and the surface of the CAM must be intact before the next experiment could be carried out. Using a stereo microscope with a magnification of 16 times, images of capillaries and blood flow can be observed, and the surface of the CAM can be observed on a computer with an HDCE-X5 camera. The test sample was preheated in an incubator, 0.3 mL of the sample was directly dripped on the CAM surface, the CAM was observed, and the initial time of the bleeding time SH, the vascular melting disappearance time SL, and the coagulation time SC was recorded within 5 minutes. The stimulation score was calculated according to the formula, and each sample was tested with six chicken embryos and the average value was taken; Formula: IS = (301-SH) × 5 ÷ 300 + (301-SL) × 7 ÷ 300 + (301-SC) × 9 ÷ 300 SH (bleeding time) - the average time when bleeding begins to occur on the CAM membrane, in seconds (s); SL ​​(vascular lysis time) - the average time when vascular lysis begins to occur on the CAM membrane, in seconds (s); SC (coagulation time) - the average time when coagulation begins to occur on the CAM membrane, in seconds (s); Test sample: the composition was diluted to 1%, the negative control was 0.9% saline, and the positive control was 1% AES (sodium laureth sulfate); Irritation score evaluation criteria: 0-1 points, no irritation; 1-8 points, mild irritation; 8-14 points, moderate irritation; 14-21 points, strong irritation. The test results are shown in Table 2. IS Scoring Irritant Example 1 7.62 Mild irritation Example 2 7.34 Mild irritation Example 3 6.58 Mild irritation Example 4 7.02 Mild irritation Example 5 6.82 Mild irritation Comparative Example 4 9.49 Moderate stimulation Negative control 0 No stimulation Positive Control 14.62 Strong stimulation As shown in Table 2, compared with Comparative Example 4, the eye irritation level of Examples 1 to 5 is reduced from moderate irritation to mild irritation, indicating that the addition of Scutellaria baicalensis root extract to the composition of the present application can significantly reduce the irritation of the composition. Compared with the rabbit eye test method of the "Technical Specification for Safety of Cosmetics" (2015 edition) through the HET-CAM test method, the HET-CAM moderate and below irritation is equivalent to no irritation to the rabbit eye. The above results show that the composition of the present application has mild and non-irritating properties.

[0063] Test Example 3: The compositions prepared in Examples 1 to 5 and Comparative Example 4 were subjected to a skin irritation test, and the skin irritation risk of the compositions was evaluated by a patch test. The test steps included: referring to the "Technical Specification for Safety of Cosmetics" (2015 Edition) (Chapter VII 2 Human Skin Patch Test), the test was conducted on 33 subjects, and the skin reactions were observed and scored 0.5 hours, 24 hours and 48 hours after the test patch tester was removed. The scoring levels were: Level 0-negative reaction; Level 1-suspicious reaction, only weak erythema; Level 2-weak positive reaction (erythema reaction): erythema, infiltration, edema, papules may occur; Level 3-strong positive reaction (herpes reaction): erythema, infiltration, edema, papules, herpes, and the reaction may exceed the test area; Level 4-very strong positive reaction (fusion herpes reaction): obvious erythema, severe infiltration, edema, fusion herpes, and the reaction exceeds the test area; the test results are shown in Table 3; Table 3 Skin patch test As shown in Table 3, the compositions prepared in Examples 1 to 5 were scored as 0 at 0.5h, 24h and 48h after the test object was removed from the spot tester, and there was no adverse reaction on the skin; in the comparative example 4, 3 cases of grade 1 adverse reaction occurred at 0.5h, and 1 case of grade 2 adverse reaction occurred at 24h; the above results indicate that the scutellaria root extract in the composition has a soothing effect, resists irritation to the skin, and can significantly improve the skin's tolerance.

[0064] Test example 4: The use effects of the shampoos prepared in Examples 1 to 5 and Comparative Example 1 were evaluated by the subjective feelings of the subjects. The number of subjects was 50, and the subjects used the shampoos 5 times. The use feelings were evaluated after using the shampoos. The evaluation items were: A: cleaning ability, B: eye irritation, C: no itching of the scalp after washing, and D: mildness. The 4-point scoring method was adopted, and the evaluation criteria were: 1 point - unsatisfactory, 2 points - general, 3 points - satisfied, and 4 points - very satisfied. The test results are shown in Table 4; Table 4 Subjective evaluation of shampoo use As shown in Table 4, compared with Comparative Example 1, Examples 1 to 5 added sodium methyl cocoyl taurate and lauryl glucoside in the composition of the shampoo raw materials. The results showed that Examples 1 to 5 all achieved 100% recognition in terms of cleaning ability, no irritation to the eyes, no itching of the scalp after washing, and mildness, while the recognition of no irritation to the eyes of Comparative Example 1 was only 44%, and the recognition of no itching of the scalp after washing and mildness was also low. The above results show that the addition of sodium methyl cocoyl taurate and lauryl glucoside to the composition of the present application can significantly increase the no irritation to the eyes, no itching of the scalp after washing, and mildness of the shampoo.

[0065] Test example 5: The cleansing bubbles prepared in Examples 6 to 8 and Comparative Examples 3 to 5 were tested, and the test items included: a trial test on sensitive skin subjects, a repair efficacy test, a soothing efficacy test, and a stability test; The trial test steps for sensitive skin subjects include: randomly distributing 30 samples of the cleansing foam prepared in Examples 6 to 8 and Comparative Examples 3 to 5 to sensitive skin subjects, cleaning their faces in the morning and evening for a total of 3 days, and evaluating whether discomfort reactions such as tingling and itching occur during the cleaning process; The steps of the repair efficacy test and the soothing efficacy test include: distributing the cleansing bubbles prepared in Examples 6 to 8 and Comparative Examples 3 to 5 to subjects with sensitive skin (subjects with dry, sensitive skin, lactic acid stinging score ≥ 3 points, and facial TEWL value ≥ 15 g / h / m 2 Before using the product, 1 day after using the product, 3 days after using the product and 7 days after using the product, the transepidermal water loss rate (TEWL value) was measured with Tewameter TM HEX to evaluate the skin repair effect, and the facial image analysis system (Visia+IPP) was used to analyze the red area of ​​the cheek (a * value) to evaluate the skin soothing effect; The stability test step includes: placing the cleansing bubbles prepared in Examples 6 to 8 and Comparative Examples 3 to 5 at -10°C, 5°C, 20°C and 45°C to test the appearance and pH changes; the test results are shown in Table 5; Table 5 Cleansing foam test results As shown in Table 5, the cleansing bubbles prepared in Examples 6 to 8 had no abnormal reactions on subjects with sensitive skin, and the TEWL value and a* value showed a downward trend over time, while the cleansing bubbles prepared in Comparative Examples 4 and 5 had a tingling sensation on the skin of subjects with sensitive skin, and even caused dryness and peeling, and the TEWL value and a* value showed an upward trend over time. The above results indicate that the cleansing bubbles prepared in the present invention have the ability to gently cleanse the skin without irritation, repair the skin barrier, and have a significant repairing effect on people with damaged or weak skin barrier function.

[0066] Test Example 6: The antibacterial effect of the cleansing bubbles prepared in Examples 9 to 11 and Comparative Examples 3, 4 and 6 was tested; the antibacterial effect test was performed according to WS / T650-2019 "Antibacterial and Antibacterial Effect Evaluation Method" 5.1.1 Suspension Quantitative Antibacterial Test Method for 6 hours for testing and calculation of the antibacterial rate; the test results are shown in Table 6; Table 6 Antibacterial effect Staphylococcus aureus (%) Propionibacterium acnes (%) Escherichia coli (%) Candida albicans (%) Example 9 35 100 77 28 Example 10 28 100 55 22 Embodiment 11 30 100 64 27 Comparative Example 3 16 100 6 15 Comparative Example 4 8 0 16 7 Comparative Example 6 2 0 14 6 As shown in Table 6, the hand sanitizers prepared in Examples 9 to 10 have inhibitory effects on Staphylococcus aureus, Propionibacterium acnes, Escherichia coli and Candida albicans, and the antibacterial effect on Propionibacterium acnes can reach 100%. In Comparative Example 3, no antioxidant was added, and it also had inhibitory effects on Staphylococcus aureus, Propionibacterium acnes, Escherichia coli and Candida albicans, but the antibacterial effects on Staphylococcus aureus, Escherichia coli and Candida albicans were lower than those in Examples 9 to 11. In Comparative Examples 4 and 6, scutellaria root extract was added, and the antibacterial rates of Comparative Examples 4 and 6 on Propionibacterium acnes were both 0%. The above results show that the hand sanitizer containing scutellaria root extract in the present application has a very high antibacterial effect on Propionibacterium acnes, and also has excellent antibacterial effects on Staphylococcus aureus, Escherichia coli and Candida albicans.

[0067] The above description is only a preferred embodiment of the present invention and does not limit the present invention in any way. Any simple modification, change and equivalent transformation made to the above embodiment based on the technical essence of the present invention still falls within the protection scope of the technical solution of the present invention.

Claims

1. A soothing, cleaning and antibacterial composition containing Scutellaria baicalensis root extract, characterized in that: Included by mass: 0.01~2 parts of Scutellaria baicalensis root extract, 3-8 parts of sodium methyl cocoyl taurate, 5-8 parts of lauryl glucoside, 5-8 parts of cocamidopropyl betaine, Antioxidant 0.01~0.2 parts, 20~40 parts of water.

2. The soothing, cleaning and antibacterial composition containing Scutellaria baicalensis root extract according to claim 1, characterized in that: The antioxidant is one or both of sodium sulfite and sodium pyrosulfite.

3. The soothing, cleaning and antibacterial composition containing Scutellaria baicalensis root extract according to claim 1, characterized in that: The baicalin content in the Scutellaria baicalensis root extract is ≥80%.

4. The soothing, cleaning and antibacterial composition containing Scutellaria baicalensis root extract according to claim 1, characterized in that: The purity of the sodium methyl cocoyl taurate is ≥27%.

5. The soothing, cleaning and antibacterial composition containing Scutellaria baicalensis root extract according to claim 1, characterized in that: The purity of cocamidopropyl betaine is ≥35%.

6. A method for preparing a soothing, cleaning and antibacterial composition containing a scutellaria root extract according to any one of claims 1 to 5, characterized in that: The method comprises the following steps: adding sodium methyl cocoyl taurate and lauryl glucoside into water, heating at 60-65 DEG C and stirring until dissolved; cooling to 40-50 DEG C after dissolved, adding scutellaria root extract and stirring until uniform; adding cocamidopropyl betaine and stirring until uniform; and adding an antioxidant and stirring evenly to prepare a soothing, cleaning and antibacterial composition containing scutellaria root extract.

7. Application of a soothing, cleansing and antibacterial composition containing scutellaria root extract in cosmetics, characterized in that: The cosmetic raw materials are made into cosmetics, wherein the cosmetic raw materials include the soothing, cleaning and antibacterial composition containing the scutellaria root extract according to any one of claims 1 to 3.

8. The use according to claim 7, characterized in that: The addition amount of the soothing, cleaning and antibacterial composition containing the scutellaria root extract is 30-60%.

9. The use according to claim 7, characterized in that: The cosmetic is one of an aqueous solution, an emulsion and an ointment.

10. The use according to claim 7 or 9, characterized in that: The cosmetic is one of shampoo, shower gel, facial cleanser and hand soap.

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