Zhuang herbal medicine liquid for treating scars and preparation method of Zhuang herbal medicine liquid

Abstract

The invention provides Zhuang herbal medicine liquid for treating scars and a preparation method, and belongs to the technical field of traditional Chinese medicine. The traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: 25-50 parts of radix notoginseng, 15-25 parts of radix ranunculi ternati, 15-25 parts of gadfly, 5-15 parts of willow bark, 15-25 parts of silkworm larva, 15-25 parts of concha arcae, 5-15 parts of lantana caerulea, 5-15 parts of wikstroemia indica, 5-15 parts of impatiens balsamina, 5-15 parts of wild sophora flavescens, 15-25 parts of Guangxi golden-edge leech, 5-15 parts of selfheal, 15-25 parts of radix taxilli, 5-15 parts of brucea javanica, 5-15 parts of kelp and 5-15 parts of adder tongue herb. The traditional Chinese medicine composition is prepared from 5-15 parts of flos chrysanthemi indici, 5-15 parts of periostracum cicadae, 5-15 parts of flos physalis alkekengi, 5-15 parts of camphor powder and 5-15 parts of plum blossom borneol powder. The pharmaceutical composition is reasonable in formula and exact in curative effect, and has the effects of easing pain, relieving itching, softening hardness, dissipating binds and promoting scar tissue softening, fading, fading and smoothing.

Description

Technical Field

[0001] The invention relates to the technical field of traditional Chinese medicines, and in particular to a herbal medicine liquid for treating scars and a preparation method thereof. Background Art

[0002] In our daily life and work, various scars are often left on the human body due to trauma, burns, surgery, sore treatment and other reasons, causing the body skin to be extremely unsightly. Human body scars can be roughly divided into the following categories: epidermal no bumps and only red purple black tea color changes of the skin color of the deposition scars; epidermal bumps and red purple black tea color changes of color spots; epidermal high convex hard and red purple changes of "pimple" scars; epidermal spontaneous high convex hard red purple changes, and constantly expand, unlimited development of the tower-like skin tumor, etc. Although scars are not considered serious diseases, they affect the beauty of the face, bring pain to patients, and cause regrets. At present, although there are various therapeutic drugs, but there are problems of poor efficacy and large side effects. The drugs sold on the market for the treatment of scars often have allergic reactions, and the treatment effect is not obvious, and the effect is slow. Summary of the invention

[0003] The purpose of the present invention is to provide a herbal liquid for treating scars and a preparation method thereof, which is mainly used for treating hypertrophic scars, scars, and keloids caused by burns, scalds, skin trauma, surgery, etc. and a preparation method thereof.

[0004] The technical solution of the present invention is achieved in this way:

[0005] The invention provides a strong herbal liquid for treating scars. The liquid is prepared from the following raw materials in parts by weight: 25-50 parts of bamboo leaf panax notoginseng, 15-25 parts of cat scratching grass, 15-25 parts of horseflies, 5-15 parts of willow barks, 15-25 parts of white silkworm, 15-25 parts of corrugated seeds, 5-15 parts of five-color flowers, 5-15 parts of king wormwood, 5-15 parts of impatiens, 5-15 parts of wild sophora flavescens, 15-25 parts of Guangxi golden-edged ant king, 5-15 parts of selfheal, 15-25 parts of ten thousand wormwood, 5-15 parts of brucea brucea, 5-15 parts of kelp, 5-15 parts of arrowroot, 5-15 parts of wild chrysanthemum, 5-15 parts of cicada shells, 5-15 parts of golden lantern, 5-15 parts of camphor powder and 5-15 parts of plum blossom borneol powder.

[0006] As a further improvement of the present invention, the invention is prepared from the following raw materials in parts by weight: 30-40 parts of bamboo leaf Panax notoginseng, 17-22 parts of cat scratching grass, 17-22 parts of horseflies, 7-12 parts of willow bark, 17-22 parts of white silkworm, 17-22 parts of corrugated seeds, 7-12 parts of five-color flower, 7-12 parts of king of wormwood, 7-12 parts of impatiens, 7-12 parts of wild sophora flavescens, 17-22 parts of Guangxi golden-edged ant king, 7-12 parts of selfheal, 17-22 parts of ten thousand celery, 7-12 parts of Brucea brucea, 7-12 parts of kelp, 7-12 parts of one arrow, 7-12 parts of wild chrysanthemum, 7-12 parts of cicada shells, 7-12 parts of golden lantern, 7-12 parts of camphor powder, and 7-12 parts of plum blossom borneol powder.

[0007] As a further improvement of the present invention, the invention is prepared from the following raw materials in parts by weight: 35 parts of bamboo leaf Panax notoginseng, 20 parts of cat scratching grass, 20 parts of horseflies, 10 parts of willow bark, 20 parts of white silkworm, 20 parts of corrugated seeds, 10 parts of five-color flower, 10 parts of king of leukorrhiza, 10 parts of impatiens, 10 parts of wild sophora flavescens, 20 parts of Guangxi golden-edged ant king, 10 parts of selfheal, 20 parts of 10000 clover, 10 parts of Brucea brucea, 10 parts of kelp, 10 parts of one arrow, 10 parts of wild chrysanthemum, 10 parts of cicada shell, 10 parts of golden lantern, 10 parts of camphor powder, and 10 parts of plum blossom borneol powder.

[0008] The present invention further protects a method for preparing the above-mentioned herbal liquid for treating scars, comprising the following steps:

[0009] Grind Panax notoginseng, cat's scratch grass, horsefly, willow bark, white silkworm, corrugated stone, five-color flower, king of wormwood, Impatiens balsamina, wild sophora flavescens, Guangxi golden-edged ant king, selfheal, schizonepeta tenuifolia, Brucea javanica, kelp, wild chrysanthemum, cicada shell, and golden lantern into coarse powder, soak in water, decocted over low heat for three times, combine the three decocted medicinal liquids, further heat and concentrate, finally add camphor powder and plum blossom borneol powder and stir repeatedly to make a strong herbal liquid for treating scars.

[0010] As a further improvement of the present invention, the mass ratio of water to coarse powder is 5-10:1.

[0011] As a further improvement of the present invention, the mass ratio of water to coarse powder is 8:1.

[0012] As a further improvement of the present invention, the soaking time is 10-15 hours.

[0013] As a further improvement of the present invention, the soaking time is 12 hours.

[0014] As a further improvement of the present invention, the concentration is performed to a relative density of 1.3-1.33.

[0015] As a further improvement of the present invention, the concentration is performed to a relative density of 1.32.

[0016] The present invention has the following beneficial effects:

[0017] The Guangxi Zhuang herbal liquid medicine of the present invention is mainly used for treating hypertrophic scars, scars and keloids caused by burns, scalds, skin trauma, surgery and the like, and the preparation method thereof. The combined medicine comprises 25-50 parts of bamboo leaf Panax notoginseng, 15-25 parts of cat scratching grass, 15-25 parts of horseflies, 5-15 parts of willow bark, 15-25 parts of white silkworm, 15-25 parts of corrugated seeds, 5-15 parts of five-color flowers, 5-15 parts of king of leukorrhiza, 5-15 parts of impatiens, 5-15 parts of wild sophora flavescens, 15-25 parts of Guangxi golden-edged ant king, 5-15 parts of selfheal, 15-25 parts of mulberry, 5-15 parts of brucea brucea, 5-15 parts of kelp, 5-15 parts of one arrowhead, The composition comprises 5-15 parts of wild chrysanthemum, 5-15 parts of cicada slough, 5-15 parts of golden lantern, 5-15 parts of camphor powder and 5-15 parts of plum blossom borneol powder. The production method is that in addition to camphor and plum blossom borneol, bamboo leaf Panax notoginseng, cat scratching grass, horsefly, willow bark, white silkworm, corrugated, five-color flower, king of wormwood, Impatiens, wild sophora flavescens, Guangxi golden-edged ant king, selfheal, 100,000 wormwood, Brucea brucea, kelp, wild chrysanthemum, cicada slough, golden lantern are beaten into coarse powder, soaked in 8 times of water for 12 hours, boiled and extracted liquid repeatedly three times with gentle and martial fire, the three decoctions are combined and further heated and concentrated to a consistency close to honey, and finally camphor powder and plum blossom borneol powder are added and repeatedly stirred into concentrated liquid. The pharmaceutical composition described in this product has reasonable prescription, definite curative effect, analgesia and itching, softening and dispersing nodules, and promoting the softening, disappearance, dilution and recovery of scar tissue. No stimulation and no toxic side effects. DETAILED DESCRIPTION

[0018] The technical solutions in the embodiments of the present invention are described clearly and completely below. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of them. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0019] Example 1

[0020] This embodiment provides a method for preparing a strong herbal liquid for treating scars.

[0021] Raw material composition (by weight): 25 parts of bamboo leaf Panax notoginseng, 15 parts of cat scratching grass, 15 parts of horseflies, 5 parts of willow bark, 15 parts of white silkworm, 15 parts of corrugated seeds, 5 parts of five-color flower, 5 parts of king of leukorrhea, 5 parts of impatiens, 5 parts of wild sophora flavescens, 15 parts of Guangxi golden edge ant king, 5 parts of selfheal, 15 parts of ten thousand clover, 5 parts of Brucea brucea, 5 parts of kelp, 5 parts of one arrow, 5 parts of wild chrysanthemum, 5 parts of cicada shell, 5 parts of golden lantern, 5 parts of camphor powder, and 5 parts of plum blossom borneol powder.

[0022] The following steps are involved:

[0023] Grind Panax notoginseng, cat's scratch grass, horsefly, willow bark, white silkworm, corrugated seed, five-color flower, king of wormwood, Impatiens balsamina, wild sophora flavescens, Guangxi golden-edged ant king, selfheal, schizonepeta tenuifolia, Brucea javanica, kelp, wild chrysanthemum, cicada shell, and golden lantern into coarse powder, soak in 5 times the weight of water for 10 hours, decocted over low heat for three times, combine the three decocted medicinal liquids, further heat and concentrate to a relative density of 1.3, finally add camphor powder and plum blossom borneol powder and stir repeatedly to make a strong herbal liquid for treating scars.

[0024] Example 2

[0025] This embodiment provides a method for preparing a strong herbal liquid for treating scars.

[0026] Raw material composition (by weight): 50 parts of bamboo leaf Panax notoginseng, 25 parts of cat scratching grass, 25 parts of horseflies, 15 parts of willow bark, 25 parts of white silkworm, 25 parts of corrugated seeds, 15 parts of five-color flower, 15 parts of king of leukorrhea, 15 parts of impatiens, 15 parts of wild sophora flavescens, 25 parts of Guangxi golden edge ant king, 15 parts of selfheal, 25 parts of 100,000 cucurbit, 15 parts of Brucea brucea, 15 parts of kelp, 15 parts of one arrow, 15 parts of wild chrysanthemum, 15 parts of cicada shells, 15 parts of golden lantern, 15 parts of camphor powder, and 15 parts of plum blossom borneol powder.

[0027] The following steps are involved:

[0028] Grind into coarse powder Panax notoginseng, cat's scratch grass, horsefly, willow bark, white silkworm, corrugated seed, five-color flower, king of wormwood, Impatiens balsamina, wild sophora flavescens, Guangxi golden-edged ant king, selfheal, schizonepeta tenuifolia, Brucea javanica, kelp, wild chrysanthemum, cicada shell, and golden lantern into powder, add 10 times the weight of water and soak for 15 hours, decocted over mild and strong fire to extract the liquid, repeat three times, combine the three decocted liquids, further heat and concentrate to a relative density of 1.33, finally add camphor powder and plum blossom borneol powder and stir repeatedly to make a strong herbal liquid for treating scars.

[0029] Example 3

[0030] This embodiment provides a method for preparing a strong herbal liquid for treating scars.

[0031] Raw material composition (by weight): 35 parts of bamboo leaf Panax notoginseng, 20 parts of cat scratching grass, 20 parts of horseflies, 10 parts of willow bark, 20 parts of white silkworm, 20 parts of corrugated seeds, 10 parts of five-color flower, 10 parts of king of leukorrhea, 10 parts of impatiens, 10 parts of wild sophora flavescens, 20 parts of Guangxi golden edge ant king, 10 parts of selfheal, 20 parts of 10000 cucurbitacins, 10 parts of Brucea brucea, 10 parts of kelp, 10 parts of one arrow, 10 parts of wild chrysanthemum, 10 parts of cicada shells, 10 parts of golden lantern, 10 parts of camphor powder, and 10 parts of plum blossom borneol powder.

[0032] The following steps are involved:

[0033] Grind Panax notoginseng, cat's scratch grass, horsefly, willow bark, white silkworm, corrugated seed, five-color flower, king of wormwood, Impatiens balsamina, wild sophora flavescens, Guangxi golden-edged ant king, selfheal, schizonepeta tenuifolia, Brucea javanica, kelp, wild chrysanthemum, cicada shell, and golden lantern into coarse powder, soak in 8 times the weight of water for 12 hours, decocted over mild and strong fire for three times, combine the three decocted medicinal liquids, further heat and concentrate to a relative density of 1.32, finally add camphor powder and plum blossom borneol powder and stir repeatedly to make a strong herbal liquid for treating scars.

[0034] Example 4

[0035] This embodiment provides a method for preparing a strong herbal liquid for treating scars.

[0036] Raw material composition (by weight): 30 parts of bamboo leaf Panax notoginseng, 17 parts of cat scratching grass, 17 parts of horseflies, 7 parts of willow bark, 17 parts of white silkworm, 17 parts of corrugated seeds, 7 parts of five-color flower, 7 parts of king of leukorrhiza, 7 parts of impatiens, 7 parts of wild sophora flavescens, 17 parts of Guangxi golden edge ant king, 7 parts of selfheal, 17 parts of ten thousand cuo, 7 parts of Brucea brucea, 7 parts of kelp, 7 parts of one arrow, 7 parts of wild chrysanthemum, 7 parts of cicada shell, 7 parts of golden lantern, 7 parts of camphor powder, and 7 parts of plum blossom borneol powder.

[0037] The following steps are involved:

[0038] Grind Panax notoginseng, cat's scratch grass, horsefly, willow bark, white silkworm, corrugated seed, five-color flower, king of wormwood, Impatiens balsamina, wild sophora flavescens, Guangxi golden-edged ant king, selfheal, schizonepeta tenuifolia, Brucea javanica, kelp, wild chrysanthemum, cicada shell, and golden lantern into coarse powder, soak in 8 times the weight of water for 12 hours, decocted over mild and strong fire for three times, combine the three decocted medicinal liquids, further heat and concentrate to a relative density of 1.32, finally add camphor powder and plum blossom borneol powder and stir repeatedly to make a strong herbal liquid for treating scars.

[0039] Example 5

[0040] This embodiment provides a method for preparing a strong herbal liquid for treating scars.

[0041] Raw material composition (by weight): 40 parts of bamboo leaf Panax notoginseng, 22 parts of cat scratching grass, 22 parts of horseflies, 12 parts of willow bark, 22 parts of white silkworm, 22 parts of corrugated seeds, 12 parts of five-color flowers, 12 parts of king of leukorrhea, 12 parts of impatiens, 12 parts of wild sophora flavescens, 22 parts of Guangxi golden edge ant king, 12 parts of selfheal, 22 parts of 100,000 cuo, 12 parts of Brucea brucea, 12 parts of kelp, 12 parts of one arrow, 12 parts of wild chrysanthemum, 12 parts of cicada shells, 12 parts of golden lantern, 12 parts of camphor powder, and 12 parts of plum blossom borneol powder.

[0042] The following steps are involved:

[0043] Grind Panax notoginseng, cat's scratch grass, horsefly, willow bark, white silkworm, corrugated seed, five-color flower, king of wormwood, Impatiens balsamina, wild sophora flavescens, Guangxi golden-edged ant king, selfheal, schizonepeta tenuifolia, Brucea javanica, kelp, wild chrysanthemum, cicada shell, and golden lantern into coarse powder, soak in 8 times the weight of water for 12 hours, decocted over mild and strong fire for three times, combine the three decocted medicinal liquids, further heat and concentrate to a relative density of 1.32, finally add camphor powder and plum blossom borneol powder and stir repeatedly to make a strong herbal liquid for treating scars.

[0044] Test Example 1

[0045] 60 healthy adult rabbits weighing 3.0-5.5kg, uneven sex, were selected and randomly divided into Example 1-5 groups and a blank control group. Rabbits in the experimental group and the control group were anesthetized by intraperitoneal injection of 1% sodium pentobarbital (30mg / kg). After successful anesthesia, the rabbits were scalded with 90°C boiling water on the back and bilateral sides for 2min to create a 1% (deep II°) area burn model. The Example 1-5 groups were given the corresponding prepared scar treatment Zhuang herbal liquid on the burn wound surface every day, 2mL / rabbit, and the blank control group was given the same amount of normal saline. The administration was continued for 2 weeks.

[0046] Cajal pyridine silver staining was used to stain nerve endings in pathological sections for qualitative research. S-100 protein immunohistochemistry was used to stain nerve endings for quantitative research. The results are shown in Table 1.

[0047] Table 1 Number of nerve endings in burn wounds and tissues after wound healing (unit: root / high power field)

[0048]

[0049] It can be seen from the above table that the scar treating Zhuangcao liquid prepared in Examples 1-3 of the present invention has a good recovery promoting function on nerve endings.

[0050] Immunohistochemistry was used to detect the expression and distribution of substance P (neuropeptide). The results are shown in Table 2.

[0051] Table 2 SP content in burn wounds and wound healing tissues (pg / mg)

[0052]

[0053] It can be seen from the above table that the scar treating Zhuangcao liquid prepared in Examples 1-3 of the present invention has a significant effect on improving the SP content.

[0054] The above description is only a preferred embodiment of the present invention and is not intended to limit the present invention. Any modifications, equivalent substitutions, improvements, etc. made within the spirit and principle of the present invention should be included in the protection scope of the present invention.

Claims

1. A herbal medicine for treating scars, characterized in that: The invention is prepared from the following raw materials in parts by weight: 25-50 parts of bamboo leaf Panax notoginseng, 15-25 parts of cat scratching grass, 15-25 parts of horseflies, 5-15 parts of willow barks, 15-25 parts of white silkworm, 15-25 parts of corrugated seeds, 5-15 parts of five-color flowers, 5-15 parts of king of leukorrhiza, 5-15 parts of impatiens, 5-15 parts of wild sophora flavescens, 15-25 parts of Guangxi golden-edged ant king, 5-15 parts of selfheal, 15-25 parts of ten thousand celery, 5-15 parts of Brucea brucea, 5-15 parts of kelp, 5-15 parts of arrowhead, 5-15 parts of wild chrysanthemum, 5-15 parts of cicada shells, 5-15 parts of golden lantern, 5-15 parts of camphor powder and 5-15 parts of plum blossom borneol powder.

2. The herbal medicine for treating scars according to claim 1, characterized in that: The invention is prepared from the following raw materials in parts by weight: 30-40 parts of bamboo leaf Panax notoginseng, 17-22 parts of cat scratching grass, 17-22 parts of horseflies, 7-12 parts of willow barks, 17-22 parts of white silkworm, 17-22 parts of corrugated seeds, 7-12 parts of flos cichorii, 7-12 parts of king leukorrhiza, 7-12 parts of impatiens, 7-12 parts of wild sophora flavescens, 17-22 parts of Guangxi golden edge ant king, 7-12 parts of selfheal, 17-22 parts of ten thousand celery, 7-12 parts of Brucea brucea, 7-12 parts of kelp, 7-12 parts of aconite, 7-12 parts of wild chrysanthemum, 7-12 parts of cicada shells, 7-12 parts of golden lantern, 7-12 parts of camphor powder and 7-12 parts of plum blossom borneol powder.

3. The herbal medicine for treating scars according to claim 2, characterized in that: The invention is prepared from the following raw materials in parts by weight: 35 parts of bamboo leaf Panax notoginseng, 20 parts of cat scratching grass, 20 parts of horseflies, 10 parts of willow barks, 20 parts of white silkworm, 20 parts of corrugated seeds, 10 parts of flos cinnamomeae, 10 parts of king leukorrhiza, 10 parts of impatiens, 10 parts of wild sophora flavescens, 20 parts of Guangxi golden edge ant king, 10 parts of selfheal, 20 parts of ten thousand clover, 10 parts of Brucea brucea, 10 parts of kelp, 10 parts of aconite, 10 parts of wild chrysanthemum, 10 parts of cicada shells, 10 parts of golden lantern, 10 parts of camphor powder and 10 parts of plum blossom borneol powder.

4. A method for preparing the herbal liquid for treating scars as claimed in any one of claims 1 to 3, characterized in that: The following steps are involved: Grind Panax notoginseng, cat's scratch grass, horsefly, willow bark, white silkworm, corrugated stone, five-color flower, king of wormwood, Impatiens balsamina, wild sophora flavescens, Guangxi golden-edged ant king, selfheal, schizonepeta tenuifolia, Brucea javanica, kelp, wild chrysanthemum, cicada shell, and golden lantern into coarse powder, soak in water, decocted over low heat for three times, combine the three decocted medicinal liquids, further heat and concentrate, finally add camphor powder and plum blossom borneol powder and stir repeatedly to make a strong herbal liquid for treating scars.

5. The preparation method according to claim 4, characterized in that: The mass ratio of water to coarse powder is 5-10:

1.

6. The preparation method according to claim 5, characterized in that: The mass ratio of water to coarse powder is 8:

1.

7. The preparation method according to claim 4, characterized in that: The soaking time is 10-15 hours.

8. The preparation method according to claim 8, characterized in that: The soaking time is 12 hours.

9. The preparation method according to claim 8, characterized in that: The concentration is performed to a relative density of 1.3-1.

33.

10. The preparation method according to claim 8, characterized in that: The concentration is to a relative density of 1.32.

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