Traditional Chinese medicine composition for improving arteriosclerosis and preparation method and application thereof

By using Chinese medicine composition composed of traditional Chinese medicines such as Qingqianliu, the problem of limited efficacy and recurrence in the treatment of arteriosclerosis in the treatment of arteriosclerosis in the treatment of existing technology has been solved, and efficient therapeutic effects are achieved.

CN119367484APending Publication Date: 2025-01-28HUNAN UNIV OF CHINESE MEDICINE
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Patent Information

Application Number
CN202411225589.5
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2024-09-03
Publication Date
2025-01-28

AI Technical Summary

Technical Problem

The prior art has limited efficacy in the treatment of arteriosclerosis and is prone to recurrence of drug treatment.

Method used

Provide a Chinese medicine composition, which is composed of green money willow, red song, Danshen, chrysanthemum, red peony, vinegar, borosity, bamboo Ru, stir -fried lady, chicken inside gold, ginkgo leaves, pearl grass, and fried lentils. Specific preparation methods improve the treatment effect.

Benefits of technology

The total effective rate of the Chinese medicine composition in the treatment of arteriosclerosis reached 88%, significantly higher than the 72%of the control group, and it is not easy to relapse.

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Abstract

The invention relates to the technical field of traditional Chinese medicines, in particular to a traditional Chinese medicine composition for improving arteriosclerosis and a preparation method and application thereof. The traditional Chinese medicine composition is prepared from the following components: cyclocarya paliurus, red yeast rice, radix salviae miltiorrhizae, endive, radix paeoniae rubra, vinegar-processed curcuma zedoary, fingered citron, bamboo shavings, fried semen raphani, endothelium corneum gigeriae galli, folium ginkgo, common leafflower herb and fried white hyacinth bean. The total effective rate of the traditional Chinese medicine composition on arteriosclerosis is 88%, and the total effective rate of a control group is 72%.
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Description

Technical Field

[0001] The present invention relates to the technical field of traditional Chinese medicines, and in particular to a traditional Chinese medicine composition for improving arteriosclerosis, and a preparation method and application thereof. Background Art

[0002] Atherosclerosis is a vascular disease that occurs with age. It occurs in adolescence and worsens and develops in old age. The most important causes of arteriosclerosis are hypertension, hyperlipidemia, and smoking. Obesity, diabetes, lack of exercise, and stress can also cause arteriosclerosis. Arteriosclerosis often affects the cardiovascular and cerebrovascular systems and is the main pathological factor for diseases such as stroke, coronary heart disease, myocardial infarction, and hypertension. Cerebral arteriosclerosis is more common in men over 40 years old and menopausal women. The main changes are fatty degeneration and cholesterol deposition in the deep layer of the arterial intima, forming atherosclerotic plaques and various secondary lesions, causing the lumen to spasm, narrow, or even occlude, which in turn causes a series of neuropsychiatric disorders.

[0003] At present, there are two main treatments for arteriosclerosis, one is surgical treatment and the other is drug treatment. Surgical treatment is expensive and causes great harm to the patient's body, so patients usually choose drug treatment. Drug treatment is mainly Western medicine treatment, which has a short course of treatment, but only treats the symptoms and not the root cause, and is prone to recurrence. Summary of the invention

[0004] In order to solve the above problems, the present invention provides a Chinese medicine composition for improving arteriosclerosis, and a preparation method and application thereof. The Chinese medicine composition provided by the present invention improves the effect of treating arteriosclerosis and is less likely to recur.

[0005] In order to achieve the above object, the present invention provides the following technical solutions:

[0006] The present invention provides a traditional Chinese medicine composition for improving arteriosclerosis, which is prepared from the following components in parts by weight:

[0007] 10-25 parts of Cyclocarya paliurus, 10-18 parts of red yeast rice, 10-25 parts of Salvia miltiorrhiza, 10-20 parts of chicory, 8-20 parts of red peony root, 4-10 parts of vinegar-curcuma, 5-15 parts of bergamot, 8-15 parts of bamboo shavings, 5-15 parts of stir-fried radish seeds, 5-15 parts of chicken's gizzard lining, 4-10 parts of ginkgo leaves, 5-15 parts of pearl grass and 8-15 parts of stir-fried white hyacinth bean.

[0008] Preferably, it is prepared from the following components in parts by weight:

[0009] 20 parts of Cyclocarya paliurus, 15 parts of red yeast rice, 20 parts of Salvia miltiorrhiza, 12 parts of chicory, 15 parts of red peony root, 6 parts of vinegar-curcuma, 10 parts of bergamot, 10 parts of bamboo shavings, 10 parts of stir-fried radish seeds, 8 parts of chicken's gizzard lining, 8 parts of ginkgo leaves, 8 parts of pearl grass and 10 parts of stir-fried white labiatae.

[0010] The present invention also provides a method for preparing the Chinese medicine composition described in the above technical solution, comprising the following steps:

[0011] 1) mixing the Cyclocarya paliurus, red yeast rice, salvia miltiorrhiza, chicory, red peony root, vinegared zedoaria, citron, bamboo shavings, stir-fried radish seeds, chicken gizzard lining, ginkgo leaf, pearl grass and stir-fried white hyacinth bean to obtain a mixed medicine;

[0012] 2) mixing the mixed medicine obtained in step 1) with water and soaking them to obtain soaked original medicine;

[0013] 3) boiling the soaked raw medicine obtained in step 2) over high heat, then boiling over low heat, filtering, and obtaining a medicinal solution and medicinal residues;

[0014] 4) The residue obtained in step 3) is decocted twice through steps 2) and 3), and the medicinal liquids obtained three times are combined to obtain a traditional Chinese medicine composition.

[0015] Preferably, the mass ratio of the mixed drug to water in step 2) is 1:8-10.

[0016] Preferably, the soaking time in step 2) is 30 to 40 minutes.

[0017] Preferably, the time of decocting over low heat in step 3) is 40 to 50 minutes.

[0018] The present invention also provides the use of the traditional Chinese medicine composition described in the above technical solution in the preparation of a drug for improving arteriosclerosis.

[0019] The beneficial effects of the present invention are:

[0020] The total effective rate of the Chinese medicinal composition provided by the invention on arteriosclerosis is 88%, while that of the control group is 72%.

[0021] In the Chinese medicinal composition for improving arteriosclerosis of the present invention:

[0022] Cyclocarya paliurus: clearing away heat and detoxifying, reducing swelling and relieving pain, dispelling wind and unblocking meridians. The "Chinese Traditional Medicine Resources" records that Cyclocarya paliurus leaves have the effects of clearing heat, relieving thirst and detoxifying. The "National Chinese Herbal Medicine Collection" records that the bark, leaves and roots of Cyclocarya paliurus have the effects of killing insects and relieving itching, and reducing inflammation, relieving pain and dispelling wind. Pharmacological studies have shown that it has the effects of lowering blood sugar, reducing fat, lowering urine sugar, and lowering blood pressure. It is clinically used in traditional Chinese medicine to treat diabetes. The medicine contains saponins, flavonoids, polysaccharides and other ingredients, which have the effect of assisting in lowering blood pressure.

[0023] Red yeast rice: sweet and warm in nature, enters the liver meridian, spleen meridian, and large intestine meridian; promotes blood circulation and removes blood stasis, strengthens the stomach and helps digestion. It is often used for food stagnation, abdominal distension, red and white diarrhea, postpartum lochia, and traumatic injuries.

[0024] Danshen: bitter, slightly cold; enters the heart, pericardium, and liver meridians, and has the effects of promoting blood circulation and regulating menstruation, removing blood stasis and relieving pain, cooling blood and eliminating carbuncle, and relieving restlessness and calming the mind. It is mainly used to treat irregular menstruation, amenorrhea, dysmenorrhea, abdominal pain due to postpartum stasis, heart pain due to blood stasis, abdominal pain, accumulation of lumps and masses, traumatic injuries, rheumatic arthralgia, sores, carbuncle, swelling and poison, fever, restlessness and coma, palpitations and insomnia.

[0025] Chicory: slightly bitter and salty, cool in nature; enters the spleen, liver, bladder, and bladder meridians. It clears the liver and promotes bile secretion, strengthens the stomach and helps digestion, and promotes diuresis and reduces swelling. It is used for damp-heat jaundice, stomachache, loss of appetite, edema, and oliguria.

[0026] Red peony root: bitter, slightly cold; enters the liver meridian. It has the effects of clearing heat and cooling blood, promoting blood circulation and removing blood stasis. It is mainly used to treat fever and toxicity, vomiting and bleeding due to blood heat, red and swollen eyes, carbuncle, liver depression and flank pain, amenorrhea and dysmenorrhea, abdominal pain due to lumps, and traumatic injuries.

[0027] Vinegar Curcuma: pungent, bitter, warm in nature; enters the liver and spleen meridians; has the effects of promoting qi and removing blood, eliminating accumulation and relieving pain. It is often used for heartache caused by blood and qi, food stagnation, abdominal distension and pain, blood stasis, amenorrhea, dysmenorrhea, lumps and masses, and injuries from falls.

[0028] Citron: Spicy, bitter, sour, warm in nature; enters the liver, spleen, stomach, and lung meridians; has the effects of soothing the liver and relieving depression, regulating qi and harmonizing the middle, and drying up dampness and resolving phlegm. It is mainly used for chest and flank pain and abdominal distension caused by liver depression and qi stagnation and liver-stomach disharmony, abdominal distension and pain caused by spleen and stomach qi stagnation, nausea and loss of appetite, prolonged cough with a lot of sputum, and chest pain.

[0029] Bamboo Shavings: sweet in taste, slightly cold in nature; enters the lung, stomach, heart, and gallbladder meridians; has the effects of clearing away heat and resolving phlegm, relieving restlessness, and stopping vomiting. It is used for cough due to phlegm heat, phlegm with gallbladder fire, palpitations, restlessness, insomnia, stroke due to phlegm, stiff tongue and speechlessness, vomiting due to stomach heat, nausea during pregnancy, and restless fetus.

[0030] Fried Radish Seeds: Spicy, sweet, neutral in nature; enters the lung, spleen, and stomach meridians; helps digestion and relieves bloating, lowers qi and resolves phlegm. Mainly used to treat food stagnation, qi stagnation, cough, asthma, excessive phlegm, chest tightness, and loss of appetite.

[0031] Chicken gizzard lining: sweet, neutral in nature; enters the spleen, stomach, small intestine, and bladder meridians; helps digestion and resolves stagnation, strengthens the spleen and stomach, and stops nocturnal emission. It is mainly used to treat food stagnation, infantile malnutrition, nocturnal emission and enuresis due to kidney deficiency, sandstone stranguria, and gallstones.

[0032] Ginkgo biloba: bitter, cool in nature; enters the lung meridian; has the effects of promoting blood circulation and removing blood stasis, dredge meridians and relieve pain, astringe the lungs and relieve asthma, remove turbidity and reduce fat. Used for blood stasis blocking meridians, chest pain and heart pain, hemiplegia due to stroke, cough and asthma due to lung deficiency, and hyperlipidemia.

[0033] Pearl grass: sweet, bitter, cool in nature; enters the liver and lung meridians; has the effects of removing dampness and jaundice, clearing away heat and detoxifying, improving eyesight, and eliminating accumulation. It is mainly used to treat damp-heat jaundice, diarrhea, stranguria, sores and swelling, snake and dog bites, red and swollen eyes, and malnutrition in children.

[0034] White lentil: sweet, slightly warm; enters the spleen and stomach meridians; has the effects of tonifying the spleen and stopping diarrhea, eliminating heat and dampness, and harmonizing and detoxifying. Mainly used for spleen deficiency diarrhea, dampness and leucorrhea, vomiting and diarrhea due to heat and dampness, alcohol poisoning or fish and crab poisoning. Contains an enzyme that non-competitively inhibits the activity of trypsin. 10mg / kg of this enzyme prolongs the coagulation time of citrate plasma from 20 seconds to 60 seconds.

[0035] In the prescription, Danshen is the main drug, which has the effects of promoting blood circulation and regulating menstruation, removing blood stasis and relieving pain. It has the reputation of "one Danshen has the same effect as four herbs". The assistants are bergamot, vinegar curcuma, and red peony root. Among them, bergamot can relieve liver depression, regulate qi and resolve phlegm. Qi is the leader of blood, and blood can flow when qi moves; vinegar curcuma can promote qi and resolve blood, eliminate accumulation and relieve pain; red peony root can clear heat and cool blood, promote blood circulation and remove blood stasis. The three herbs are combined, and qi and blood are regulated, which helps Danshen to promote blood circulation and remove blood stasis. Phlegm, food accumulation, and pathogenic heat are most likely to stagnate the qi mechanism, which is a common cause of blood stasis; after blood stasis is formed, it in turn hinders the qi mechanism, which is also a secondary cause of endogenous phlegm and pathogenic heat. Activating blood circulation is often combined with regulating qi, resolving phlegm, digesting food, and clearing heat, so ginkgo leaves, bamboo shavings, white lentils, chicken gizzard lining, stir-fried radish seeds, chicory, green willow, and pearl grass are used as assistants. Among them, Ginkgo biloba can promote blood circulation and remove blood stasis, dredge meridians and relieve pain, remove turbidity and reduce lipids, Bamboo Shavings can clear heat and resolve phlegm, White lentil can nourish the spleen and remove dampness, consolidate the foundation and nourish the essence, so as to help Ginkgo biloba and Bamboo Shavings to remove phlegm and turbidity; Chicken gizzard lining can help digestion and resolve accumulation, strengthen the spleen and stomach, stir-fried radish seeds can help digestion and eliminate swelling, reduce qi and resolve phlegm, the two medicines are used together, strengthen the spleen and digestion to help promote blood circulation; Chicory can clear the liver and promote bile, Green Palaeochrysum can clear heat and detoxify, reduce swelling and relieve pain, dispel wind and dredge meridians, Pearl grass can clear heat and detoxify, and eliminate accumulation, the three medicines are used together to play the role of clearing heat. Red yeast rice is used as an adjuvant, and "Compendium of Materia Medica" says: "It enters the camp and breaks blood, dries the stomach and digests food, and promotes blood circulation and blood. It treats injuries from falls". Red yeast rice leads the medicine into the camp and blood, and has the functions of promoting blood circulation and removing blood stasis, strengthening the stomach and digesting food. Coenzyme Q10 can be separated after fermentation of red yeast rice, which is an activator of cell metabolism and cell respiration, can improve the function of mitochondrial respiration, and promote oxidative phosphorylation reaction. It is a natural oxidant produced by cells themselves, which can inhibit mitochondrial peroxidation and protect the structural integrity of the biological membrane of vascular endothelial cells. The combination of various medicines works together from different angles, such as regulating qi, promoting blood circulation, resolving phlegm, digesting food, and clearing away heat, and helps to promote blood circulation and remove blood stasis. DETAILED DESCRIPTION

[0036] The present invention provides a Chinese medicine composition for improving arteriosclerosis, which is prepared from the following components in parts by weight: 10-25 parts of Cyclocarya paliurus, 10-18 parts of Red Yeast, 10-25 parts of Salvia miltiorrhiza, 10-20 parts of Chicory, 8-20 parts of Red Peony Root, 4-10 parts of Curcuma zedoariae, 5-15 parts of Citron, 8-15 parts of Bamboo Shavings, 5-15 parts of Fried Radish Seeds, 5-15 parts of Chicken's Gizzard Stone, 4-10 parts of Ginkgo Biloba Leaves, 5-15 parts of Pearl Grass, and 8-15 parts of Fried White Hyacinthus Beans. In the present invention, the Chinese medicine composition is preferably prepared from the following components in parts by weight: 20 parts of Cyclocarya paliurus, 15 parts of Red Yeast, 20 parts of Salvia miltiorrhiza, 12 parts of Chicory, 15 parts of Red Peony Root, 6 parts of Curcuma zedoariae, 10 parts of Citron, 10 parts of Bamboo Shavings, 10 parts of Fried Radish Seeds, 8 parts of Chicken's Gizzard Stone, 8 parts of Ginkgo Biloba Leaves, 8 parts of Pearl Grass, and 10 parts of Fried White Hyacinthus Beans. The present invention has no special limitation on the source of the above-mentioned medicines, and conventional commercially available Chinese herbal medicines can be used.

[0037] The present invention also provides a method for preparing the Chinese medicine composition described in the above technical solution, comprising the following steps:

[0038] 1) mixing the Cyclocarya paliurus, red yeast rice, salvia miltiorrhiza, chicory, red peony root, vinegared zedoaria, citron, bamboo shavings, stir-fried radish seeds, chicken gizzard lining, ginkgo leaf, pearl grass and stir-fried white hyacinth bean to obtain a mixed medicine;

[0039] 2) mixing the mixed medicine obtained in step 1) with water and soaking them to obtain soaked original medicine;

[0040] 3) boiling the soaked raw medicine obtained in step 2) over high heat, then boiling over low heat, filtering, and obtaining a medicinal solution and medicinal residues;

[0041] 4) The residue obtained in step 3) is decocted twice through steps 2) and 3), and the medicinal liquids obtained three times are combined to obtain a traditional Chinese medicine composition.

[0042] The invention mixes the Cyclocarya paliurus, red yeast rice, salvia miltiorrhiza, chicory, red peony root, vinegared zedoaria, citron, bamboo shavings, fried radish seeds, chicken gizzard lining, ginkgo leaf, pearl grass and fried white hyacinth bean to obtain a mixed medicine.

[0043] The present invention mixes the obtained mixed medicine with water and soaks it to obtain the soaked original medicine. In the present invention, the mass ratio of the mixed medicine to water is preferably 1:8 to 10. In the present invention, the soaking time is preferably 30 to 40 minutes.

[0044] The present invention boils the soaked original medicine with high heat until it boils, then boils it with low heat, and filters it to obtain the medicine liquid and medicine residue. In the present invention, the time of the low heat boiling is preferably 40 to 50 minutes.

[0045] In the present invention, the method of using the Chinese medicine composition is preferably: taking the Chinese medicine composition twice a day, once in the morning and once in the evening. 15 days is a course of treatment, and each course of treatment is separated by 2 to 3 days.

[0046] The present invention also provides the use of the traditional Chinese medicine composition described in the above technical solution in the preparation of a drug for improving arteriosclerosis.

[0047] In order to further illustrate the present invention, the present invention is described in detail below in conjunction with embodiments, but they should not be construed as limiting the scope of protection of the present invention.

[0048] Example 1

[0049] A Chinese medicine composition for improving arteriosclerosis is prepared from the following components:

[0050] 20g of Cyclocarya paliurus, 15g of Monascus yeast, 15g of Salvia miltiorrhiza, 12g of Chicory, 15g of Red Peony Root, 6g of Curcuma zedoaria with vinegar, 8g of Citron, 12g of Rhizoma Anemarrhenae, 10g of stir-fried radish seeds, 10g of chicken gizzard lining, 8g of Ginkgo biloba leaves, 10g of Phyllostachys pearlwort and 15g of stir-fried white lentil.

[0051] Preparation method:

[0052] Mix Cyclocarya paliurus, red yeast rice, salvia miltiorrhiza, chicory, red peony root, zedoaria officinalis, bergamot, bamboo shavings, stir-fried radish seeds, chicken gizzard lining, ginkgo leaf, pearl grass and stir-fried white hyacinth bean to obtain a mixed medicine;

[0053] 2) mixing the mixed drug obtained in step 1) with 8 times the mass of water and soaking for 30 minutes to obtain soaked original drug;

[0054] 3) boiling the soaked raw medicine obtained in step 2) over high heat until boiling, then boiling over low heat for 40 minutes, filtering to obtain a medicinal solution and medicinal residues;

[0055] 4) The residue obtained in step 3) is decocted twice through steps 2) and 3), and the medicinal liquids obtained three times are combined to obtain a traditional Chinese medicine composition.

[0056] Example 2

[0057] A Chinese medicine composition for improving arteriosclerosis is prepared from the following components:

[0058] 15g of Cyclocarya paliurus, 18g of red yeast rice, 20g of Salvia miltiorrhiza, 10g of chicory, 10g of red peony root, 9g of Curcuma zedoaria with vinegar, 10g of bergamot, 15g of bamboo shavings, 12g of stir-fried radish seeds, 8g of chicken gizzard lining, 10g of ginkgo leaf, 12g of pearl grass and 10g of stir-fried white hyacinth bean.

[0059] Preparation method:

[0060] Mix Cyclocarya paliurus, red yeast rice, salvia miltiorrhiza, chicory, red peony root, zedoaria officinalis, bergamot, bamboo shavings, stir-fried radish seeds, chicken gizzard lining, ginkgo leaf, pearl grass and stir-fried white hyacinth bean to obtain a mixed medicine;

[0061] 2) mixing the mixed drug obtained in step 1) with 10 times the mass of water and soaking for 40 minutes to obtain soaked original drug;

[0062] 3) boiling the soaked raw medicine obtained in step 2) over high heat until boiling, then boiling over low heat for 50 min, filtering to obtain a medicinal solution and medicinal residues;

[0063] 4) The residue obtained in step 3) is decocted twice through steps 2) and 3), and the medicinal liquids obtained three times are combined to obtain a traditional Chinese medicine composition.

[0064] Example 3

[0065] A Chinese medicine composition for improving arteriosclerosis is prepared from the following components:

[0066] 25g of Cyclocarya paliurus, 10g of red yeast rice, 12g of Salvia miltiorrhiza, 15g of chicory, 12g of red peony root, 8g of Curcuma zedoaria with vinegar, 9g of citron, 10g of Rhizoma Anemarrhenae, 15g of stir-fried radish seeds, 12g of chicken gizzard lining, 12g of ginkgo leaf, 8g of pearl grass and 12g of stir-fried white lentil.

[0067] Preparation method:

[0068] Mix Cyclocarya paliurus, red yeast rice, salvia miltiorrhiza, chicory, red peony root, zedoaria officinalis, bergamot, bamboo shavings, stir-fried radish seeds, chicken gizzard lining, ginkgo leaf, pearl grass and stir-fried white hyacinth bean to obtain a mixed medicine;

[0069] 2) mixing the mixed drug obtained in step 1) with 10 times the mass of water and soaking for 35 minutes to obtain soaked original drug;

[0070] 3) boiling the soaked raw medicine obtained in step 2) over high heat until boiling, then boiling over low heat for 45 minutes, filtering to obtain a medicinal solution and medicinal residues;

[0071] 4) The residue obtained in step 3) is decocted twice through steps 2) and 3), and the medicinal liquids obtained three times are combined to obtain a traditional Chinese medicine composition.

[0072] Drug efficacy example

[0073] 1. General Information

[0074] 200 patients with confirmed arteriosclerosis were selected for clinical observation. The main symptoms were dizziness, headache, tinnitus, blurred vision, poor sleep, memory loss, palpitations, panic, chest tightness, chest pain, abdominal pain, refractory hypertension, limb heaviness, distending pain, numbness, lower limb coldness, intermittent claudication, cramps, etc. Then they were randomly divided into a treatment group and a control group. There were 150 cases in the treatment group, including 92 males and 58 females, aged 41-75 years old, with the shortest course of disease being 5 months and the longest being 4 years and 8 months.

[0075] There were 50 cases in the control group, including 30 males and 20 females, aged 40-74 years. The shortest course of disease was 4 months and the longest was 4 years and 6 months.

[0076] The treatment group and the control group were statistically comparable in terms of gender, age, disease course, severity of the disease and clinical characteristics (t test, P value <0.5).

[0077] Diagnostic criteria: All cases were diagnosed according to the TCM disease diagnosis and efficacy criteria issued by the State Administration of Traditional Chinese Medicine of the People's Republic of China's TCM industry standards.

[0078] 2. Treatment Methods

[0079] The treatment group was divided into 3 groups, and each group took the Chinese medicine composition prepared by Examples 1 to 3 of the present invention respectively. Each group was randomly divided into 50 patients, and the taking method was: take the Chinese medicine composition twice a day, once in the morning and once in the evening, 15 days as a course of treatment, 3 days between each course of treatment, and 6 courses of treatment were taken.

[0080] The control group took Tongmai granules purchased from the market orally, twice a day, once in the morning and once in the evening, 10g each time, 15 days as a course of treatment, with an interval of 3 days between each course, and 6 courses of treatment were taken.

[0081] 3. Efficacy evaluation criteria

[0082] The efficacy of TCM syndrome treatment was determined according to the Guiding Principles for Clinical Research of New TCM Drugs: cured: clinical symptoms disappeared, and syndrome score decreased by ≥95%; markedly effective: clinical symptoms were significantly relieved, and syndrome score decreased by ≥70% but less than 95%; effective: clinical symptoms were alleviated, and syndrome score decreased by ≥30% but less than 70%; ineffective: clinical symptoms remained basically unchanged, and syndrome score decreased by <30% after treatment; aggravated: clinical symptoms worsened, and syndrome score did not decrease but showed an upward trend after treatment.

[0083] 4. Treatment Outcomes

[0084] The treatment results are shown in Table 1.

[0085] Table 1 The therapeutic effect of Chinese medicine composition on arteriosclerosis

[0086]

[0087] It can be seen from Table 1 that the total effective rate of the Chinese medicine composition provided by the present invention on arteriosclerosis is 88%, while that of the control group is 72%.

[0088] Although the above embodiment describes the present invention in detail, it is only a part of the embodiments of the present invention, not all of the embodiments. People can also obtain other embodiments based on this embodiment without creativity, and these embodiments all fall within the protection scope of the present invention.

Claims

1. A Chinese medicine composition for improving arteriosclerosis, characterized in that: Prepared from the following components in parts by weight: 10-25 parts of Cyclocarya paliurus, 10-18 parts of red yeast rice, 10-25 parts of Salvia miltiorrhiza, 10-20 parts of chicory, 8-20 parts of red peony root, 4-10 parts of vinegar-curcuma, 5-15 parts of bergamot, 8-15 parts of bamboo shavings, 5-15 parts of stir-fried radish seeds, 5-15 parts of chicken's gizzard lining, 4-10 parts of ginkgo leaves, 5-15 parts of pearl grass and 8-15 parts of stir-fried white hyacinth bean.

2. The Chinese medicine composition according to claim 1, characterized in that: Prepared from the following components in parts by weight: 20 parts of Cyclocarya paliurus, 15 parts of red yeast rice, 20 parts of Salvia miltiorrhiza, 12 parts of chicory, 15 parts of red peony root, 6 parts of vinegar-curcuma, 10 parts of bergamot, 10 parts of bamboo shavings, 10 parts of stir-fried radish seeds, 8 parts of chicken's gizzard lining, 8 parts of ginkgo leaves, 8 parts of pearl grass and 10 parts of stir-fried white labiatae.

3. A method for preparing the Chinese medicine composition according to claim 1 or 2, characterized in that: The following steps are involved: 1) mixing the Cyclocarya paliurus, red yeast rice, salvia miltiorrhiza, chicory, red peony root, vinegared zedoaria, citron, bamboo shavings, stir-fried radish seeds, chicken gizzard lining, ginkgo leaf, pearl grass and stir-fried white hyacinth bean to obtain a mixed medicine; 2) mixing the mixed medicine obtained in step 1) with water and soaking them to obtain soaked original medicine; 3) boiling the soaked raw medicine obtained in step 2) over high heat, then boiling over low heat, filtering, and obtaining a medicinal solution and medicinal residues; 4) The residue obtained in step 3) is decocted twice through steps 2) and 3), and the medicinal liquids obtained three times are combined to obtain a traditional Chinese medicine composition.

4. The preparation method according to claim 3, characterized in that: In the step 2), the mass ratio of the mixed drug to water is 1:8-10.

5. The preparation method according to claim 3, characterized in that: The soaking time in step 2) is 30 to 40 minutes.

6. The preparation method according to claim 3, characterized in that: The time of decocting over low heat in step 3) is 40 to 50 minutes.

7. Use of the Chinese medicine composition according to claim 1 or 2 in the preparation of a drug for improving arteriosclerosis.