Oral cleaning and nursing composition for tooth whitening

Abstract

The invention relates to the technical field of whitening gels, in particular to an oral cavity cleaning and nursing composition for tooth whitening, which is prepared from the following components: a thickening agent, an activating agent, an auxiliary agent, a grafting modified compound, urea peroxide, phthalimide peroxyhexanoic acid, glycerol, ammonium persulfate and water, the tooth bleaching and whitening gel prepared by the invention has the effect of removing exogenous stains, and the active ingredients in the tooth bleaching and whitening gel are subjected to chemical reaction with attached colors on the surfaces of the teeth to play a role in decomposing and removing hyperpigmentation on the teeth by coating the surfaces of the teeth with the tooth bleaching and whitening gel, so that the tooth bleaching and whitening gel can be used for whitening the teeth. Therefore, the tooth whitening agent is separated from the tooth surface and recovers the original color of the tooth, so that the whitening effect is achieved.

Description

Technical Field

[0001] The invention relates to the technical field of whitening gels, in particular to an oral cleaning and care composition for teeth whitening. Background Art

[0002] Teeth are one of the most important organs in the human mouth and have many key functions: Chewing food: This is the most important function of teeth. Through chewing, teeth grind food into small pieces to facilitate subsequent digestion and absorption. Human teeth are divided into two categories: front teeth and back teeth. The front teeth are mainly used to bite off and tear food, while the back teeth are used to grind food; Assisting pronunciation: Teeth also play an important role in the pronunciation process. They limit the range of movement of the tongue during pronunciation, as well as the positional relationship between the tongue, lips, and teeth, thereby affecting the accuracy of pronunciation and the clarity of speech; Beautifying appearance: Neat and white teeth can significantly improve a person's appearance, making people look healthier, more confident and attractive. Therefore, modern society pays more and more attention to oral beauty, including the increasing demand for teeth whitening, correction and implants.

[0003] With the improvement of national consumption level, people's awareness of oral care has been greatly improved, especially in the past decade, from only focusing on basic oral cleaning to now focusing on the neatness and whiteness of teeth. A mouthful of white teeth has become the "standard" for healthy people today. In daily life, the residues of tobacco, tea, coffee, colored foods, etc. are easily deposited on the tooth surface through the salivary protein on the tooth surface to form an acquired film. If it is not cleaned promptly and effectively, after a long period of accumulation, it can cause the teeth to gradually turn yellow or even black, forming exogenous tooth stains, which not only affects oral hygiene, but also affects the appearance of teeth. Summary of the invention

[0004] In view of the problems existing in the prior art, the present invention provides an oral cleaning and care composition for teeth whitening.

[0005] To achieve the above object, the present invention provides the following technical solutions:

[0006] A tooth whitening oral cleaning and care composition comprises the following ingredients by weight: 10-15 parts of a thickener, 2-3 parts of an activator, 0.01-0.02 parts of an auxiliary agent, 30-40 parts of a grafted modified composite, 8-15 parts of urea peroxide, 2-3 parts of phthalimidoperoxycaproic acid, 5-8 parts of glycerol, 0.2-0.3 parts of ammonium persulfate, and 40-50 parts of water.

[0007] As a further technical solution, the thickener is sodium carboxymethyl cellulose.

[0008] As a further technical solution, the activator is: sodium hexametaphosphate.

[0009] As a further technical solution, the auxiliary agent is calcium fluoride.

[0010] As a further technical solution, the method for preparing the graft-modified composite is:

[0011] First, sodium alginate is added into deionized water to prepare a sodium alginate solution;

[0012] Add cyclodextrin to deionized water, stir and mix evenly to obtain a cyclodextrin dispersion;

[0013] preparing nitric acid into a nitric acid solution;

[0014] Add the cyclodextrin dispersion into the reactor, then adjust the pH of the cyclodextrin dispersion to weak acidity, and then add the sodium alginate solution into the reactor while stirring. After the addition is complete, add the nitric acid solution and the enhancer, continue stirring for 2 hours, let it stand for 30 minutes, and then freeze-dry and crush it in vacuum to obtain a grafted modified composite.

[0015] As a further technical solution, the mass fraction of the sodium alginate solution is 4-5%;

[0016] The mass fraction of the cyclodextrin dispersion is 12-14%;

[0017] The mass fraction of the nitric acid solution is 1.0-1.2%.

[0018] As a further technical solution, the mixing volume ratio of the sodium alginate solution, the cyclodextrin dispersion and the nitric acid solution is 1:1.2:0.8;

[0019] The enhancer accounts for 5% of the mass of the nitric acid solution.

[0020] As a further technical solution, the reinforcing agent is nano titanium dioxide.

[0021] As a further technical solution, the preparation method of the teeth bleaching and whitening gel is: add each component in weight to a container in sequence, stir and mix evenly, set for 20 hours, and then seal to obtain.

[0022] As a further technical solution, the method for using the gel for teeth bleaching and whitening is: apply the gel for teeth bleaching and whitening to the surface of the patient's teeth to form a coating layer with a thickness of 0.5mm±0.1mm, use a purple light source with a wavelength of 380-400nm to irradiate the coating layer for 5-8min, then let it stand for 10min, and finally wash off the coating layer.

[0023] Before using the gel, make sure the tooth surface is clean and free of stains so that the gel can adhere better to the teeth and improve the whitening effect.

[0024] After use, rinse your mouth thoroughly with clean water to remove gel residue and avoid any impact on oral health.

[0025] Compared with the prior art, the present invention has the following beneficial effects:

[0026] The tooth bleaching and whitening gel prepared by the present invention has the effect of removing exogenous stains. By coating the tooth surface with the bleaching and whitening gel prepared by the present invention, the active ingredients in the tooth can chemically react with the attached color on the tooth surface to decompose and remove the pigmentation on the tooth, thereby separating the pigmentation from the tooth surface and restoring the original color of the tooth, thereby achieving a whitening effect.

[0027] The present invention introduces a grafted modified composite in the preparation process of the bleaching and whitening gel, which can not only improve the stability of the gel, but also contain bleaching components, which can enable the bleaching and whitening gel to continuously release the bleaching components, thereby continuously decomposing the color-limiting components attached to the tooth surface, and under the action of blue light, the photocatalytic effect can be further enhanced, and the color components attached to the tooth surface can be more thoroughly decomposed and separated, thereby greatly improving the bleaching and whitening effect on the teeth, and the bleaching and whitening effect on the teeth is not irritating or corrosive to the teeth, and is safe to use. BRIEF DESCRIPTION OF THE DRAWINGS

[0028] In order to more clearly illustrate the technical solutions of the embodiments of the present invention, the accompanying drawings required for describing the embodiments will be briefly introduced below. Obviously, the accompanying drawings described below are only some embodiments of the present invention. For ordinary technicians in this field, other accompanying drawings can be obtained based on these accompanying drawings without paying creative work.

[0029] Figure 1 Picture of teeth before using the product;

[0030] Figure 2 This is a picture of teeth improvement after using the product. DETAILED DESCRIPTION

[0031] The technical solutions in the embodiments of the present invention are described clearly and completely below. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of them. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0032] The following are specific embodiments:

[0033] Example 1

[0034] A tooth whitening oral cleaning and care composition comprises the following ingredients by weight: 10 parts of sodium carboxymethyl cellulose, 2 parts of sodium hexametaphosphate, 0.01 parts of calcium fluoride, 30 parts of grafted modified composite, 8 parts of urea peroxide, 2 parts of phthalimidoperoxycaproic acid, 5 parts of glycerol, 0.2 parts of ammonium persulfate and 40 parts of water.

[0035] The preparation method of the graft modified composite is as follows:

[0036] First, sodium alginate is added into deionized water to prepare a sodium alginate solution;

[0037] Add cyclodextrin to deionized water, stir and mix evenly to obtain a cyclodextrin dispersion;

[0038] preparing nitric acid into a nitric acid solution;

[0039] Add the cyclodextrin dispersion into the reactor, then adjust the pH of the cyclodextrin dispersion to weak acidity, and then add the sodium alginate solution into the reactor while stirring. After the addition is complete, add the nitric acid solution and the enhancer, continue stirring for 2 hours, let it stand for 30 minutes, and then freeze-dry and crush it in vacuum to obtain a grafted modified composite.

[0040] The mass fraction of sodium alginate solution is 4%;

[0041] The mass fraction of the cyclodextrin dispersion is 12%;

[0042] The mass fraction of the nitric acid solution is 1.0%.

[0043] The mixing volume ratio of sodium alginate solution, cyclodextrin dispersion and nitric acid solution is 1:1.2:0.8;

[0044] The enhancer accounts for 5% of the mass of the nitric acid solution.

[0045] The reinforcing agent is nano titanium dioxide.

[0046] The preparation method of the teeth bleaching and whitening gel is as follows: each component is added into a container in order according to its weight portion, stirred and mixed evenly, shaped for 20 hours, and then sealed to obtain.

[0047] The preparation method of the gel for teeth bleaching and whitening is as follows: apply the gel for teeth bleaching and whitening to the surface of the patient's teeth to form a coating layer with a thickness of 0.5mm±0.1mm, irradiate the coating layer with a violet light source with a wavelength of 380nm for 5min, then let it stand for 10min, and finally wash off the coating layer.

[0048] Example 2

[0049] A tooth whitening oral cleaning and care composition comprises the following ingredients by weight: 12 parts of sodium carboxymethyl cellulose, 2.5 parts of sodium hexametaphosphate, 0.018 parts of calcium fluoride, 33 parts of a grafted modified composite, 12 parts of urea peroxide, 2.8 parts of phthalimidoperoxycaproic acid, 6 parts of glycerol, 0.24 parts of ammonium persulfate, and 45 parts of water.

[0050] The preparation method of the graft modified composite is as follows:

[0051] First, sodium alginate is added into deionized water to prepare a sodium alginate solution;

[0052] Add cyclodextrin to deionized water, stir and mix evenly to obtain a cyclodextrin dispersion;

[0053] preparing nitric acid into a nitric acid solution;

[0054] Add the cyclodextrin dispersion into the reactor, then adjust the pH of the cyclodextrin dispersion to weak acidity, and then add the sodium alginate solution into the reactor while stirring. After the addition is complete, add the nitric acid solution and the enhancer, continue stirring for 2 hours, let it stand for 30 minutes, and then freeze-dry and crush it in vacuum to obtain a grafted modified composite.

[0055] The mass fraction of sodium alginate solution is 4.5%;

[0056] The mass fraction of the cyclodextrin dispersion is 13%;

[0057] The mass fraction of the nitric acid solution is 1.1%.

[0058] The mixing volume ratio of sodium alginate solution, cyclodextrin dispersion and nitric acid solution is 1:1.2:0.8;

[0059] The enhancer accounts for 5% of the mass of the nitric acid solution.

[0060] The reinforcing agent is nano titanium dioxide.

[0061] The preparation method of the teeth bleaching and whitening gel is as follows: each component is added into a container in order according to its weight portion, stirred and mixed evenly, shaped for 20 hours, and then sealed to obtain.

[0062] The preparation method of the gel for teeth bleaching and whitening is as follows: apply the gel for teeth bleaching and whitening to the surface of the patient's teeth to form a coating layer with a thickness of 0.5mm±0.1mm, irradiate the coating layer with a violet light source with a wavelength of 390nm for 7 minutes, then let it stand for 10 minutes, and finally wash off the coating layer.

[0063] Example 3

[0064] A tooth whitening oral cleaning and care composition comprises the following ingredients by weight: 15 parts of sodium carboxymethyl cellulose, 3 parts of sodium hexametaphosphate, 0.02 parts of calcium fluoride, 40 parts of grafted modified composites, 15 parts of urea peroxide, 3 parts of phthalimidoperoxycaproic acid, 8 parts of glycerol, 0.3 parts of ammonium persulfate, and 50 parts of water.

[0065] The preparation method of the graft modified composite is as follows:

[0066] First, sodium alginate is added into deionized water to prepare a sodium alginate solution;

[0067] Add cyclodextrin to deionized water, stir and mix evenly to obtain a cyclodextrin dispersion;

[0068] preparing nitric acid into a nitric acid solution;

[0069] Add the cyclodextrin dispersion into the reactor, then adjust the pH of the cyclodextrin dispersion to weak acidity, and then add the sodium alginate solution into the reactor while stirring. After the addition is complete, add the nitric acid solution and the enhancer, continue stirring for 2 hours, let it stand for 30 minutes, and then freeze-dry and crush it in vacuum to obtain a grafted modified composite.

[0070] The mass fraction of sodium alginate solution is 5%;

[0071] The mass fraction of the cyclodextrin dispersion is 14%;

[0072] The mass fraction of the nitric acid solution is 1.2%.

[0073] The mixing volume ratio of sodium alginate solution, cyclodextrin dispersion and nitric acid solution is 1:1.2:0.8;

[0074] The enhancer accounts for 5% of the mass of the nitric acid solution.

[0075] The reinforcing agent is nano titanium dioxide.

[0076] The preparation method of the teeth bleaching and whitening gel is as follows: each component is added into a container in order according to its weight portion, stirred and mixed evenly, shaped for 20 hours, and then sealed to obtain.

[0077] The preparation method of the gel for teeth bleaching and whitening is as follows: apply the gel for teeth bleaching and whitening to the surface of the patient's teeth to form a coating layer with a thickness of 0.5mm±0.1mm, irradiate the coating layer with a violet light source with a wavelength of 400nm for 8min, then let it stand for 10min, and finally wash off the coating layer.

[0078] Comparative Example 1: This comparative example is basically the same as Example 2, except that the graft-modified composite is replaced by an equal amount of cyclodextrin.

[0079] Comparative Example 2: This comparative example is basically the same as Example 2, except that no reinforcing agent is added during the preparation of the graft-modified composite.

[0080] test:

[0081] The experiment was designed according to the standard of "T / COCIA7-2020 Laboratory Evaluation Method for the Efficacy Evaluation of Toothpaste for Oral Cleaning and Care Products for Removing Exogenous Stains" and the literature "Systematic Evaluation Method for a New Whitening Toothpaste to Remove Exogenous Stains from Teeth" and "Research Progress on the Mechanism and Removal Methods of Natural Tooth Staining". The whitening efficacy of the product was verified through negative control, and the teeth whitening efficacy of the product was explored by testing its ability to remove exogenous stains.

[0082] Test Materials:

[0083] Main reagent materials: isolated bovine permanent teeth, standard toothbrush, phytic acid, hydrochloric acid, sodium carbonate, artificial saliva, gastric mucin, coffee, black tea;

[0084] Main instruments: constant temperature box, colorimeter;

[0085] Staining solution: Dissolve gastric mucin with hot water, then add coffee and black tea, stir evenly, and store at 2-8℃ for later use. The final concentration of each component is: coffee 4.0g / L, black tea 4.0g / L;

[0086] Negative control group: pure water;

[0087] Specific steps:

[0088] (1) Bovine tooth screening: Select the permanent teeth of the bovine, scrape off all soft tissue residues and clean them thoroughly.

[0089] (2) Acid etching: Immerse the permanent teeth in 1% hydrochloric acid, stir for 1 minute, rinse with water, and then immerse in saturated sodium carbonate solution and stir for 60 seconds.

[0090] (3) Rinse with clean water; finally, immerse in 1% phytic acid solution, stir for 60 seconds, and rinse with clean water. Staining: After preparing the staining solution, place the acid-etched bovine teeth in a beaker filled with the staining solution in a constant temperature box for staining for 12 days.

[0091] (4) Test: After dyeing, remove the teeth, rinse off the surface dirt, and wipe off the surface moisture. Use a colorimeter to measure the whiteness value (L * ), 8 in each group. After the teeth were numbered, the whiteness value (L * ) and visually evaluate the Lobene stain index of the sample. The index grading is shown in the table below.

[0092] Table 1 Lobene stain index grading

[0093]

[0094] Simulated gel use process:

[0095] The teeth were cleaned once a day. After each cleaning, the samples of the embodiment and the comparative example were applied to the surface of the permanent teeth of the bovine. The samples were treated according to the methods used in the embodiment and the comparative example, and the whiteness value and the Lobene stain index of the permanent teeth of the bovine were evaluated on day 0, day 7, and day 14. In the test, after each cleaning, the teeth were put back into the artificial saliva for soaking.

[0096] Calculate L before and after brushing * The difference between the values ​​△L * , △L * =L * 使用后 - L * 使用前 , calculate the Lobene spot area score and Lobene spot degree score;

[0097] Judgment basis:

[0098] Table 2

[0099]

[0100] Table 3 Test data after 7 days of testing

[0101]

[0102]

[0103]

[0104] Table 4 Test data after 14 days of testing

[0105]

[0106]

[0107] The experimental results show:

[0108] (1) After 7 days of using the product, the improvement in the enamel whiteness value L value was 7.97, and the teeth became significantly whiter compared with the control group. After 7 days of using the product, the Lonebe stain area level decreased by 0.75, and the tooth stain area was significantly reduced compared with the control group. After 7 days of using the product, the Lonebe stain degree decreased by 0.29, and there was no significant change in the tooth stain degree compared with the control group.

[0109] (2) After 14 days of product use, the improvement in the enamel whiteness value L value was 14.21, and the teeth became significantly whiter compared with the control group. After 14 days of product use, the Lonebe stain area level decreased by 1.43, and the tooth stain area was significantly reduced compared with the control group. After 14 days of product use, the Lonebe stain degree decreased by 1.57, and the tooth stain degree was significantly lighter compared with the control group.

[0110] Reference Figure 1 and Figure 2 In summary, it can be seen that the product of the present invention has the effect of removing exogenous spots.

[0111] The preferred embodiments of the present invention disclosed above are only used to help illustrate the present invention. The preferred embodiments do not describe all the details in detail, nor do they limit the invention to the specific implementation methods described. Obviously, many modifications and changes can be made according to the content of this specification. This specification selects and specifically describes these embodiments in order to better explain the principles and practical applications of the present invention, so that those skilled in the art can understand and use the present invention well. The present invention is limited only by the claims and their full scope and equivalents.

Claims

1. A composition for cleaning and caring for teeth whitening oral cavity, characterized in that: The invention comprises the following ingredients by weight: 10-15 parts of thickener, 2-3 parts of activator, 0.01-0.02 parts of auxiliary agent, 30-40 parts of graft modified compound, 8-15 parts of urea peroxide, 2-3 parts of phthalimido peroxycaproic acid, 5-8 parts of glycerol, 0.2-0.3 parts of ammonium persulfate and 40-50 parts of water.

2. The oral cleaning and care composition for teeth whitening according to claim 1, characterized in that: The thickener is sodium carboxymethyl cellulose.

3. The oral cleaning and care composition for teeth whitening according to claim 2, characterized in that: The activator is sodium hexametaphosphate.

4. The oral cleaning and care composition for teeth whitening according to claim 1, characterized in that: The auxiliary agent is calcium fluoride.

5. The oral cleaning and care composition for teeth whitening according to claim 1, characterized in that: The preparation method of the graft modified composite is: First, sodium alginate is added into deionized water to prepare a sodium alginate solution; Add cyclodextrin to deionized water, stir and mix evenly to obtain a cyclodextrin dispersion; preparing nitric acid into a nitric acid solution; Add the cyclodextrin dispersion into the reactor, then adjust the pH of the cyclodextrin dispersion to weak acidity, and then add the sodium alginate solution into the reactor while stirring. After the addition is complete, add the nitric acid solution and the enhancer, continue stirring for 2 hours, let it stand for 30 minutes, and then freeze-dry and crush it in vacuum to obtain a grafted modified composite.

6. The oral cleaning and care composition for teeth whitening according to claim 5, characterized in that: The mass fraction of the sodium alginate solution is 4-5%; The mass fraction of the cyclodextrin dispersion is 12-14%; The mass fraction of the nitric acid solution is 1.0-1.2%.

7. The oral cleaning and care composition for teeth whitening according to claim 6, characterized in that: The mixing volume ratio of the sodium alginate solution, the cyclodextrin dispersion and the nitric acid solution is 1:1.2:0.8; The enhancer accounts for 5% of the mass of the nitric acid solution.

8. The oral cleaning and care composition for teeth whitening according to claim 7, characterized in that: The reinforcing agent is nano titanium dioxide.

9. The oral cleaning and care composition for teeth whitening according to claim 8, characterized in that: The preparation method of the teeth bleaching and whitening gel comprises the following steps: adding each component in parts by weight into a container in sequence, stirring and mixing evenly, setting the mixture for 20 hours, and then sealing the mixture to obtain the gel.

10. The oral cleaning and care composition for teeth whitening according to claim 1, characterized in that: The method for using the gel for teeth bleaching and whitening is as follows: applying the gel for teeth bleaching and whitening to the surface of the patient's teeth to form a coating layer with a thickness of 0.5 mm±0.1 mm, irradiating the coating layer with a violet light source with a wavelength of 380-400 nm for 5-8 minutes, then leaving it to stand for 10 minutes, and finally washing off the coating layer.

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