Aerosol exposure test device

By designing an aerosol exposure test device that uses a cabin and a hard frame support structure, equipped with half-body protective clothing and high-efficiency filtering device, the aerosol leakage risks and isolation operation problems in existing equipment are solved, and an effective isolation and safe operating environment for high-risk operations are achieved.

CN119594497APending Publication Date: 2025-03-11INST OF MEDICAL SUPPORT TECH OF ACAD OF SYST ENG OF ACAD OF MILITARY SCI
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Patent Information

Application Number
CN202411895747.8
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2022-05-11
Publication Date
2025-03-11

AI Technical Summary

Technical Problem

Existing bioaerosol exposure infection equipment poses a risk of aerosol leakage, and the equipment is large in size and heavy in weight, making it difficult to meet the requirements of biosafety protection and isolation operations.

Method used

Aerosol exposure test device was designed, using a cabin and a hard frame support structure, equipped with half-body protective clothing and high-efficiency filtering device, which achieved physical isolation for high-risk operations through negative pressure control and airtight isolation.

Benefits of technology

It effectively reduces the risk of aerosol leakage, improves the protection level of operators, prevents environmental pollution, and realizes flexible disassembly and assembly and easy handling of the device.

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Abstract

The invention discloses an aerosol exposure test device which can be used as an isolation device for a test with a biological aerosol exposure infection risk. The aerosol exposure test device of the present invention comprises: a cabin; a half-body type protective suit is arranged in the cabin body; the half-body protective clothing is at least of a double-layer structure; the half-body type protective clothing is further provided with an air supply filtering device. Air outlets are respectively formed in the neck and the sleeves of the half-body protective clothing inner layer; a working table top is arranged at a horizontal position which can be touched by the half-body type protective clothing in the cabin body; an air inlet device and an air exhaust device are arranged on the side wall of the cabin body. Through a cabin body and a hard frame supporting structure, flexible disassembly and assembly of the test device are realized, and the test device is easy to carry; based on negative pressure control, airtight isolation and high-grade personnel protection design mechanisms, physical isolation of high-risk operation is achieved, protection on operators is effectively achieved, and pollution to the environment is prevented.
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Description

[0001] This application is a divisional application of the invention patent whose parent application name is "An aerosol exposure isolation device"; the application number of the parent application is: CN202210513299.5; the application date of the parent application is: 2022.05.11. Technical Field

[0002] The invention relates to the technical field of isolation protection devices, and in particular to an aerosol exposure test device. Background Art

[0003] Aerosol refers to a gaseous dispersion system composed of solid or liquid particles suspended in a gas medium. The density of the solid or liquid particles can be slightly different from that of the gas medium, or it can be very different. Bioaerosol refers to an aerosol containing biological particles, including bacteria, viruses, allergenic pollen, mold spores, fern spores, and parasite eggs. In addition to the characteristics of general aerosols, it is also infectious and allergenic.

[0004] In the process of conducting life science research, in order to develop vaccines and drugs for the prevention and treatment of infectious diseases, it is necessary to conduct pathogenic microorganism related experiments, such as animal infection experiments. Bioaerosol exposure infection equipment is a scientific device specifically used to conduct aerosol infection experiments on small animals. However, there is a risk of aerosol leakage during the experiment. Since the aerosol itself has harmful effects on the human body and the environment, the aerosol should be avoided as much as possible from leaking into the external environment of the equipment. In addition, the existing bioaerosol exposure infection equipment is large in size and heavy in weight. The isolation device needs to be equipped with a large sealed door and needs to be placed at the bottom of the isolation device. The operation panel is set on the side, and the top needs to be opened, animal cages are placed, and animals are caught. At the same time, the test personnel need to have a large range of activities. In order to facilitate the relevant test operations, the isolation device needs to be equipped with various forms of operation interfaces, and items need to be transferred during the test. Therefore, the existing isolation device is difficult to meet the requirements of biosafety protection and isolation operation of bioaerosol exposure infection equipment, and is affected by the size of the inlet and outlet channels of the operating environment. The large volume of the isolation device cannot achieve the non-specificity of site selection.

[0005] To this end, the development and design of isolation devices that can effectively reduce the risk of bioaerosol leakage from medium and large instruments and equipment such as animal bioaerosol exposure and infection equipment has become a technical issue that needs to be urgently addressed at this stage. Summary of the invention

[0006] The purpose of the present invention is to provide an aerosol exposure test device to solve the problems existing in the above-mentioned prior art.

[0007] The present invention adopts the following technical solutions:

[0008] The present invention provides an aerosol exposure test device, comprising a cabin; a half-body protective suit is arranged in the cabin; the half-body protective suit is at least a double-layer structure; the half-body protective suit is also equipped with an air supply filter device, the air supply filter device comprises a fan, a filter box and a high-efficiency filter, and is used to provide clean air for the half-body protective suit, the high-efficiency filter is installed in the filter box, and is used to send air in the environment into the half-body protective suit after high-efficiency filtration; the air supply filter device is connected with the interior of the half-body protective suit through an air pipe, and the half-body protective suit is supported by positive pressure; the inner layer of the half-body protective suit is respectively provided with air outlets at the neck and sleeve positions; a work surface is provided at a horizontal position in the cabin that is accessible to the half-body protective suit; and an air inlet device and an air exhaust device are provided on the side wall of the cabin.

[0009] Preferably, it also includes a hard frame, which is fixedly connected by overlapping; the cabin is a flexible cabin; the cabin is provided with a connecting edge at a corresponding position for connecting the hard frame.

[0010] Preferably, the work surface is provided with a hollow in the middle to allow operators to move around;

[0011] The bottom side of the half-body protective suit is sealed to the raised flange at the hollow lower portion of the work surface, and the cabin is sealed to the flange.

[0012] Preferably, isolation operation gloves are also provided on the test device at the bottom of the half-body protective suit, and the isolation operation gloves are sealed and connected to the cabin body, and are used to operate the bioaerosol exposure infection equipment placed at the bottom of the aerosol exposure test device.

[0013] Preferably, a sealing door is further provided on the side of the cabin away from the exhaust device, and the sealing door is used for entry and exit of bioaerosol exposure infection equipment;

[0014] A transfer device is also provided on the upper part of the work surface of the cabin body for transferring small items. The transfer device is sealed with the cabin body and is sealed with a sealed bag on the outside. The transferred items are placed in the sealed bag and removed after being tied and sealed or heat-sealed to complete the transfer of items from the inside of the test device to the outside during the experiment. The items can also be placed in the sealed bag outside the test device, and the sealed bag can be tied and sealed inside the test device or heat-sealed outside the test device, and the items can be taken out of the sealed bag by cutting inside the test device to complete the transfer process of the items from the outside to the inside of the test device.

[0015] Preferably, the air intake device is an air intake high-efficiency filter device, which is sealed and connected to the cabin. The air intake high-efficiency filter device is provided with an air inlet, and the air inlet is provided with a quick interface, which can be quickly connected to the disinfection pipeline, and a high-efficiency filter is installed inside.

[0016] Preferably, the exhaust device is a high-efficiency exhaust filter device, including a first-stage exhaust high-efficiency filter device and a second-stage exhaust high-efficiency filter device;

[0017] The first-stage exhaust high-efficiency filter device is provided with an air inlet, which is sealed and connected to the cabin. A high-efficiency air filter is installed inside the first-stage exhaust high-efficiency filter device, and an exhaust port is provided downstream. The exhaust port is sealed and connected to the second-stage exhaust high-efficiency filter device through a connecting pipeline. The connecting pipeline is provided with aerosol interfaces near both ends, respectively. The aerosol interfaces are divided into a front-end interface and a rear-end interface. The front-end interface is used for the injection of aerosol upstream of the second-stage exhaust high-efficiency filter device, and the rear-end interface is used for aerosol sampling downstream of the first-stage exhaust high-efficiency filter device and aerosol sampling upstream of the second-stage exhaust high-efficiency filter device.

[0018] The second-stage exhaust high-efficiency filter device is provided with an exhaust high-efficiency filter inside, and a downstream aerosol sampling port and an exhaust fan are provided downstream; after the exhaust fan is started, the interior of the aerosol exposure test device presents a negative pressure. Under the action of the negative pressure, the air outside the test device enters the test device through the air inlet device and gradually reaches equilibrium.

[0019] Preferably, the air inlet of the air inlet device and the air outlet of the exhaust device are both provided with quick flanges. When the internal space of the test device and the air inlet device and the exhaust device are disinfected, the disinfection machine is respectively connected to the air inlet and the exhaust outlet through pipelines to form a closed loop, and gas circulation disinfection is performed through the exhaust fan.

[0020] Preferably, a control panel is also provided on one side of the test device, a controller is provided and connected to the control panel, and the control panel is provided with a start / stop button and a speed regulating device for the air supply filter device and the exhaust fan;

[0021] The hollow in the middle of the work surface is a circular hollow;

[0022] A lighting device is also provided at the top of the separation device, and the lighting device is connected to the control panel to facilitate lighting control during the operation process.

[0023] Preferably, the flexible material is an extrudable and deformable material; the flexible material comprises a thermal insulation protective layer and an internal anti-scratch layer from the outside to the inside; or, the flexible material comprises a thermal insulation protective layer, a dimensional reinforcement layer and an internal anti-scratch layer from the outside to the inside.

[0024] Compared with the prior art, the aerosol exposure test device provided by the present invention has the following beneficial effects:

[0025] 1. The present invention uses the cabin and the hard frame support structure to achieve flexible disassembly and assembly of the test device, which is easy to carry and can be arranged in operating environments of various required sizes and can be conveniently installed in existing laboratories;

[0026] 2. The present invention is based on negative pressure control, airtight isolation and high-level personnel protection design mechanisms, which realizes the physical isolation of high-risk operations, can effectively solve the protection of operators, and prevent pollution to the environment. BRIEF DESCRIPTION OF THE DRAWINGS

[0027] In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings required for use in the embodiments will be briefly introduced below. Obviously, the drawings described below are only some embodiments of the present invention. For ordinary technicians in this field, other drawings can be obtained based on these drawings without paying creative work.

[0028] Figure 1 A schematic diagram of the structure of an aerosol exposure test device according to an embodiment of the present invention is shown;

[0029] Figure 2 A schematic diagram of an isolation operation glove for an aerosol exposure test device according to an embodiment of the present invention is shown;

[0030] Figure 3 A schematic diagram of an air inlet device of an aerosol exposure test device according to an embodiment of the present invention is shown;

[0031] Figure 4 A schematic diagram of an exhaust device of an aerosol exposure test device according to an embodiment of the present invention is shown;

[0032] In the figure: 1. Cabin; 2. Half-body protective clothing; 3. Work surface; 4. Air inlet device; 401. Air inlet; 402. Quick connector (flange); 403. High efficiency filter; 5. Exhaust device; 501. First-stage exhaust high efficiency filter device; 511. Air inlet; 512. High efficiency air filter; 513. Exhaust port; 502. Second-stage exhaust high efficiency filter device; 522. Downstream aerosol sampling port; 523. Exhaust fan; 503. Aerosol interface; 531. Front interface; 532. Rear interface; 6. Hard frame; 7. Protective clothing air supply filter device; 701. Protective clothing air supply fan; 702. Protective clothing air supply filter box; 703. Protective clothing air supply high efficiency filter; 8. Isolation operation gloves; 9. Sealed door; 10. Transfer device; 11. Control panel; 12. Protective clothing mounting base; 13. Disinfection interface; 14. Lighting equipment. DETAILED DESCRIPTION

[0033] The exemplary embodiments of the present application will be described in more detail below with reference to the accompanying drawings. Although the exemplary embodiments of the present application are shown in the accompanying drawings, it should be understood that the present application can be implemented in various forms and should not be limited by the embodiments set forth herein. On the contrary, these embodiments are provided in order to enable a more thorough understanding of the present application and to fully convey the scope of the present application to those skilled in the art.

[0034] See also Figure 1 The present invention provides an aerosol exposure test device, comprising: a cabin 1, a half-body protective suit 2 is arranged in the cabin 1, the half-body protective suit 2 can effectively protect the operator to avoid harmful gases in the operation process causing human body harm; a work surface 3 is arranged in the cabin 1 at a horizontal position that the half-body protective suit 2 can touch, the work surface can be used for placing objects in the operation process, and it is convenient for the operator to perform test operations within the range of activities; an air inlet device 4 and an air exhaust device 5 are arranged on the side wall of the cabin 1 to ensure the air pressure control in the cabin, so as to realize safe operation and effectively protect the operator and the environment from being invaded by harmful substances.

[0035] The cabin 1 is a flexible cabin, which is made of flexible materials. The flexible material is an extrudable and deformable material, including but not limited to fiber fabrics such as glass cloth supplemented with foamed polyurethane or polyvinyl butyral, etc. It has toughness, elasticity and good safety. It can adapt to the pressure changes in the operating room during the exposure and infection operation, and can also ensure that a safe isolation environment is provided during the operation process. Preferably, the flexible material comprises a thermal insulation protective layer and an internal anti-scratch layer from the outside to the inside; preferably, the flexible material comprises a thermal insulation protective layer, a dimensional reinforcement layer and an internal anti-scratch layer from the outside to the inside; wherein the thermal insulation protective layer comprises but is not limited to nylon, polyester film and similar materials, and is used to ensure that the operating environment temperature and the external environment temperature will not affect the internal operating temperature of the test isolation device; the dimensional reinforcement layer comprises but is not limited to poly(p-phenylene terephthalamide), sub-phenylene materials and similar materials, which have low density, high strength, good toughness, high temperature resistance, and are easy to process and form, and are used to ensure that the test isolation device has a certain shape and strength, and ensures the isolation effect of the operating space and the inside and outside of the device; the internal anti-scratch layer comprises but is not limited to p-phenylene terephthalamide and meta-polyaramid products, which have dimensional stability, strong mechanical properties and good flexibility, and can effectively prevent damage to the flexible cabin during the isolation operation while bringing good sealing, further avoiding the occurrence of exposure incidents and damage to personnel and the environment, and improving operational safety. The use of this protective material can prevent the operating environment from being affected by the external temperature, the isolated operating environment is stable, and the pressure changes inside and outside the device will not affect the normal operation. It has good airtightness, avoids the damage that the isolation operation may cause to the flexible cabin, and improves the safety of personnel and the environment in the isolation operation.

[0036] The aerosol exposure test device also includes a rigid frame 6, which is fixedly connected by overlapping, and the cabin 1 is provided with a connecting edge at a corresponding position for connecting the rigid frame 6. The connecting edge is made of the material used for the flexible cabin, and at least two pairs of edges are provided diagonally on the upper bottom surface of the cabin rigid frame 6 to ensure the stability of the cabin space; combined with the flexible cabin, the support structure of the flexible cabin and the rigid frame can be ensured, and flexible disassembly and easy handling can be effectively realized, and it can be arranged in an operating environment with a variety of required sizes of space, and can be conveniently installed in an existing laboratory.

[0037] The half-body protective suit 2 is at least a double-layer structure. The material selected for the structure can be the same as the flexible material of the flexible cabin, or other flexible materials with similar functions can be selected. While ensuring the integrity and safety of the cabin operation, it is convenient for personnel to operate flexibly in the test isolation device.

[0038] The half-body protective suit 2 is also provided with an air supply filter device 7, which comprises a fan 701, a filter box 702 and a high-efficiency filter 703, and is used to provide clean air for the half-body protective suit 2; the high-efficiency filter 703 is installed in the filter box 702, and is used to send the air in the environment into the half-body protective suit 2 after high-efficiency filtration; the air supply filter device 7 is connected with the interior of the half-body protective suit 2 through an air pipe, and supports the half-body protective suit 2 through positive pressure; the inner layer of the half-body protective suit 2 is provided with air outlets at the neck, sleeves and other positions, which can meet the breathing, ventilation and protection requirements of the operator.

[0039] See also Figure 2 , a hollow is provided in the middle of the work surface 3, and the operator can perform the test operation in the test device at this position to meet the activity requirements of the operator; the bottom side of the half-body protective suit 2 is sealed with the flange raised at the bottom of the hollow of the work surface 3, and the cabin 1 of the aerosol exposure test device is sealed with the flange; preferably, a protective suit mounting base 12 is provided at the connection; preferably, the hollow in the middle of the work surface 3 is a circular hollow. The sealed connection between the bottom side of the half-body protective suit 2 and the work surface 3 can effectively ensure the isolation of the inside and outside of the operating environment, achieve the safety of the operation, and thus ensure the safety of personnel and the environment. The test device at the bottom of the half-body protective suit 2 is also provided with isolation operation gloves 8, which are sealed with the cabin 1 and are used to operate the biological aerosol exposure infection equipment placed at the bottom of the aerosol exposure test device. Using the half-body protective suit 2 as the personnel isolation operation equipment and the isolation operation gloves 8 installed at the bottom as the auxiliary operation equipment can effectively increase the activity range of the personnel isolation operation and solve the problem of isolation operation of the aerosol exposure infection equipment.

[0040] See also Figure 3 A sealing door 9 is also provided on the side of the cabin 1 away from the exhaust filter device, and the sealing door 9 is used for the entry and exit of the bioaerosol exposure infection equipment.

[0041] A transfer device 10 is also provided on the upper part of the work surface 3 of the cabin 1 for transferring small items. The transfer device 10 is sealed with the cabin 1 and can be sealed with a sealed bag on the outside. The transfer items can be placed in the sealed bag and removed after being sealed to complete the transfer of items inside the test device to the outside during the experiment.

[0042] The air inlet device 4 arranged on the side wall of the cabin 1 is an air inlet high-efficiency filter device, which is sealed and connected to the cabin 1. The air inlet high-efficiency filter device is provided with an air inlet 401, and the air inlet 401 is provided with a quick interface 402, which can be quickly connected to the disinfection pipeline, and a high-efficiency filter 403 is installed inside it; wherein, the high-efficiency filter 403 selects a high-efficiency filter that meets the standards of biosafety laboratories; preferably, a high-efficiency / ultra-high-efficiency air particle filter (HEPA / ULPA), or a similar filter composed of a filter membrane with a hard shell support and an extended, pleated medium can be selected to ensure that the air in the test device reaches the specified cleanliness by filtering dust and other particles outside the test device; and filter out possible contaminated particles outside the device to protect samples and avoid cross-contamination between samples and during operations.

[0043] See also Figure 4, an exhaust device 5 is arranged on the side wall of the cabin 1, and the exhaust filter device 5 is a high-efficiency exhaust filter device; it includes a first-stage exhaust high-efficiency filter device 501 and a second-stage exhaust high-efficiency filter device 502; preferably, the first-stage exhaust high-efficiency filter device 501 is provided with an air inlet 511, and the air inlet 511 is sealed and connected to the cabin 1, a high-efficiency air filter 512 is installed inside the first-stage exhaust high-efficiency filter device 501, and an exhaust port 513 is arranged downstream, and the exhaust port 513 is sealed and connected to the second-stage exhaust high-efficiency filter device 502 through a pipeline, and aerosol interfaces 503 are respectively arranged near both ends of the connecting pipeline, and the aerosol interface 503 is divided into a front end interface 531 and a rear end interface 532, the front end interface 531 is used for the injection of aerosol upstream of the second-stage exhaust high-efficiency filter device 502, and the rear end interface 532 is used for the downstream aerosol sampling of the first-stage exhaust high-efficiency filter device 501 and the second-stage exhaust high-efficiency filter device 502 Upstream aerosol sampling; the second-stage exhaust high-efficiency filter device 502 is provided with an exhaust high-efficiency filter inside, and a downstream aerosol sampling port 522 and an exhaust fan 523 are provided downstream; the first-stage exhaust high-efficiency filter device 501 and the second-stage exhaust high-efficiency filter device 502 are both provided with high-efficiency filters, and high-efficiency filters that meet the standards of biosafety laboratories are selected; preferably, a high-efficiency / ultra-high-efficiency air particle filter (HEPA / ULPA), or a similar filter composed of a filter membrane with a hard shell support and an extended, pleated medium can be selected to filter out dust and other particles outside the test device to ensure that the air in the test device reaches the specified cleanliness; by filtering out dangerous particles such as aerosols that may be generated during the test process, the samples are protected and cross-contamination between samples and during operations is avoided; and further avoid the direct discharge of dangerous particles into the environment during the air discharge process inside the test device to ensure the safety of personnel and the environment.

[0044] After the exhaust fan 523 is started, the inside of the aerosol exposure test device presents negative pressure. Under the effect of negative pressure, the air outside the test device enters the inside of the test device through the air inlet device 4 and gradually reaches equilibrium. Based on the principles of negative pressure control, airtight isolation and high-level personnel protection, physical isolation of high-risk operations is achieved, effectively solving the problem of protecting operators and preventing environmental pollution.

[0045] The air inlet 401 of the air inlet device 4 and the exhaust port of the exhaust device 5 are both provided with quick flanges. When the internal space of the test device and the air inlet device 4 and the exhaust device 5 are disinfected, the sterilizer can be connected to the air inlet 511 and the exhaust port respectively through pipelines to form a closed loop. The exhaust fan is used for gas circulation disinfection to ensure the safe control of the operating environment and samples and avoid possible cross contamination.

[0046] A control panel 11 is also provided on one side of the test device. A controller is provided and connected to the control panel 11. The control panel 11 is provided with an air supply filter device 7 of the half-body protective suit 2 and a start / stop button and a speed regulating device of the exhaust fan 523, which can realize the pressure control in the cabin and the operating environment control during operation; during the circulation disinfection process, it can also be used for gas flow and pressure control; the control panel 11 is set in a position that the half-body protective suit 2 can reach, and it can also facilitate the operator to effectively control the air intake, exhaust and cabin pressure during operation.

[0047] The hollowing in the middle of the work surface 3 inside the test device is a circular hollowing, which is convenient for the operator to move in a larger range, and also convenient for the half-body protective suit 2 to be sealed and connected to the flange raised at the lower part of the hollowing of the work surface 3 through the protective suit mounting base 12, and further sealed and connected to the flange through the cabin 1, forming a sealing structure of the test device. The circular hollowing facilitates flange sealing connection and also facilitates multi-angle operation of the operator, which improves the sealing effect and makes the operation more flexible.

[0048] A lighting device 14 is also provided on the top of the test device. The lighting device 14 is controlled by a control panel 11 and is used to turn on the lighting device when the test requires it.

[0049] The structural design of the present invention is ingenious. It adopts a flexible cabin and a hard frame support structure, which realizes flexible disassembly and assembly, easy transportation, and can be conveniently installed in an existing laboratory; a half-body protective suit is adopted as personnel isolation operation equipment, and gloves installed on the bottom are used as auxiliary operation equipment, which effectively improves the range of activities of personnel isolation operation and solves the problem of isolation operation of aerosol exposure infection equipment; based on the principles of negative pressure control, airtight isolation and high-level personnel protection, physical isolation of high-risk operations is realized, effectively solving the problem of protecting operators and preventing environmental pollution.

[0050] It should be noted that the term "comprises" or any other variation thereof is intended to cover non-exclusive inclusion, so that a process, method, article or device including a series of elements includes not only these elements, but also other elements not explicitly listed, or also includes elements inherent to such process, method, article or device. In the absence of further restrictions, the elements defined by the sentence "comprises..." do not exclude the existence of other identical elements in the process, method, article or device including the elements.

[0051] The above are only embodiments of the present application and are not intended to limit the present application. For those skilled in the art, the present application may have various changes and variations. Any modification, equivalent replacement, improvement, etc. made within the spirit and principle of the present application should be included within the scope of the claims of the present application.

Claims

1. An aerosol exposure test device, characterized in that: The invention comprises a cabin (1); a half-body protective suit (2) is arranged in the cabin (1); the half-body protective suit (2) is at least a double-layer structure; the half-body protective suit (2) is also provided with an air supply filter device (7), the air supply filter device (7) comprises a fan (701), a filter box (702) and a high-efficiency filter (703), and is used to provide clean air for the half-body protective suit (2); the high-efficiency filter (703) is installed in the filter box (702), and is used to filter the environment The air in the half-body protective suit (2) is sent into the half-body protective suit (2) after being filtered with high efficiency; the air supply filter device (7) is connected to the interior of the half-body protective suit (2) through an air pipe, and the half-body protective suit (2) is supported by positive pressure; the inner layer of the half-body protective suit (2) is provided with air outlets at the neck and sleeve positions respectively; a work surface (3) is provided at a horizontal position within the cabin (1) that is accessible to the half-body protective suit (2); and the side wall of the cabin (1) is provided with an air inlet device (4) and an air exhaust device (5).

2. The aerosol exposure test device according to claim 1, characterized in that: It also comprises a hard frame (6), wherein the hard frame (6) is fixedly connected by overlapping; the cabin (1) is a flexible cabin; and the cabin (1) is provided with a connecting edging at a corresponding position for connecting the hard frame (6).

3. The aerosol exposure test device according to claim 1 or 2, characterized in that: The work surface (3) is provided with a hollow in the middle to allow the operator to move around; the bottom side of the half-body protective suit (2) is sealedly connected to a flange protruding from the lower part of the hollow of the work surface (3), and the cabin (1) is sealedly connected to the flange.

4. The aerosol exposure test device according to claim 3, characterized in that: An isolation operation glove (8) is also provided on the test device at the bottom of the half-body protective suit (2). The isolation operation glove (8) is sealedly connected to the cabin (1) and is used to operate a bioaerosol exposure infection device placed at the bottom of the aerosol exposure test device.

5. The aerosol exposure test device according to claim 1 or 2, characterized in that: A sealing door (9) is also provided on the side of the cabin (1) away from the exhaust device (5), and the sealing door (9) is used for entry and exit of bioaerosol exposure infection equipment; A transfer device (10) is also provided on the upper part of the work surface (3) of the cabin (1) for transferring small items. The transfer device (10) is sealed with the cabin (1) and is externally sealed with a sealed bag. The transferred items are placed in the sealed bag and are removed after being sealed to complete the transfer of the items inside the test device to the outside during the experiment.

6. The aerosol exposure test device according to claim 1, characterized in that: The air intake device (4) is an air intake high-efficiency filtering device, which is sealed and connected to the cabin (1). The air intake high-efficiency filtering device is provided with an air inlet (401), and the air inlet (401) is provided with a quick interface (402). The quick interface (402) can be quickly connected to a disinfection pipeline, and a high-efficiency filter (403) is installed inside the quick interface.

7. The aerosol exposure test device according to claim 6, characterized in that: The exhaust device (5) is a high-efficiency exhaust filter device, comprising a first-stage exhaust high-efficiency filter device (501) and a second-stage exhaust high-efficiency filter device (502); The first-stage exhaust high-efficiency filter device (501) is provided with an air inlet (511), the air inlet (511) is sealed and connected to the cabin (1), a high-efficiency air filter (512) is installed inside the first-stage exhaust high-efficiency filter device (501), an exhaust port (513) is provided downstream, the exhaust port (513) is sealed and connected to the second-stage exhaust high-efficiency filter device (502) via a connecting pipeline, the connecting pipeline is provided with aerosol interfaces (503) near both ends, the aerosol interface (503) is divided into a front end interface (531) and a rear end interface (532), the front end interface (531) is used for injecting aerosol upstream of the second-stage exhaust high-efficiency filter device (502), and the rear end interface (532) is used for sampling aerosol downstream of the first-stage exhaust high-efficiency filter device (501) and sampling aerosol upstream of the second-stage exhaust high-efficiency filter device (502); The second-stage exhaust high-efficiency filter device (502) is provided with an exhaust high-efficiency filter (521) therein, and a downstream aerosol sampling port (522) and an exhaust fan (523) are provided downstream thereof. After the exhaust fan (523) is started, a negative pressure is present inside the aerosol exposure test device. Under the effect of the negative pressure, the air outside the test device enters the test device through the air inlet device (4) and gradually reaches equilibrium.

8. The aerosol exposure test device according to claim 7, characterized in that: The air inlet (401) of the air inlet device (4) and the air outlet of the air exhaust device (5) are both provided with quick flanges. When the internal space of the test device and the air inlet device (4) and the air exhaust device (5) are disinfected, the disinfection machine is connected to the air inlet (511) and the air outlet respectively through pipelines to form a closed loop, and gas circulation disinfection is performed through the exhaust fan.

9. The aerosol exposure test device according to claim 8, characterized in that: A control panel (11) is also provided on one side of the test device, and a controller is provided which is connected to the control panel (11). The control panel (11) is provided with a start / stop button and a speed regulating device for the air supply filter device (7) and the exhaust fan (523); The hollow in the middle of the work surface (3) is a circular hollow; A lighting device (14) is also provided at the top of the test device, and the lighting device (14) is connected to the control panel (11).

10. The aerosol exposure test device according to claim 2, characterized in that: The flexible material is a material that can be squeezed and deformed; the flexible material is a thermal insulation protective layer and an internal anti-scratch layer from the outside to the inside; or, the flexible material is a thermal insulation protective layer, a dimensional reinforcement layer and an internal anti-scratch layer from the outside to the inside.